Zamaneh Kassiri, Ph.D. - Publications

2002 University of Toronto, Toronto, ON, Canada 
Animal Physiology Biology, Cell Biology

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chen X, Zhabyeyev P, Azad AK, Vanhaesebroeck B, Grueter CE, Murray AG, Kassiri Z, Oudit GY. Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction. Journal of Molecular and Cellular Cardiology. 157: 17-30. PMID 33887328 DOI: 10.1016/j.yjmcc.2021.04.004  0.36
2021 Hu M, Jana S, Kilic T, Wang F, Shen M, Winkelaar G, Oudit GY, Rayner K, Zhang DW, Kassiri Z. Loss of TIMP4 (Tissue Inhibitor of Metalloproteinase 4) Promotes Atherosclerotic Plaque Deposition in the Abdominal Aorta Despite Suppressed Plasma Cholesterol Levels. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315522. PMID 33792349 DOI: 10.1161/ATVBAHA.120.315522  0.36
2021 Jamieson KL, Darwesh AM, Sosnowski DK, Zhang H, Shah S, Zhabyeyev P, Yang J, Hammock BD, Edin ML, Zeldin DC, Oudit GY, Kassiri Z, Seubert JM. Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury. International Journal of Molecular Sciences. 22. PMID 33567578 DOI: 10.3390/ijms22041691  0.36
2020 Oh Y, Yang S, Liu X, Jana S, Izaddoustdar F, Gao X, Debi R, Kim DK, Kim KH, Yang P, Kassiri Z, Lakin R, Backx PH. Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vulnerability in Intensely Exercised Mice. Frontiers in Physiology. 11: 605671. PMID 33424629 DOI: 10.3389/fphys.2020.605671  0.44
2020 Zhang H, Viveiros A, Nikhanj A, Nguyen Q, Wang K, Wang W, Freed DH, Mullen JC, MacArthur R, Kim DH, Tymchak W, Sergi CM, Kassiri Z, Wang S, Oudit GY. The Human Explanted Heart Program: A translational bridge for cardiovascular medicine. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1867: 165995. PMID 33141063 DOI: 10.1016/j.bbadis.2020.165995  0.36
2020 Jana S, Chute M, Hu M, Winkelaar G, Owen CA, Oudit GY, Kassiri Z. ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)-Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314600. PMID 32522006 DOI: 10.1161/ATVBAHA.120.314600  0.36
2019 Masoud AG, Lin J, Azad AK, Farhan MA, Fischer C, Zhu LF, Zhang H, Sis B, Kassiri Z, Moore RB, Kim D, Anderson CC, Vederas JC, Adam BA, Oudit GY, et al. Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injury. The Journal of Clinical Investigation. PMID 31738185 DOI: 10.1172/Jci128469  0.36
2019 Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, ... Kassiri Z, et al. Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. Proceedings of the National Academy of Sciences of the United States of America. PMID 31189595 DOI: 10.1073/Pnas.1900152116  0.36
2018 Patel VB, Zhabyeyev P, Chen X, Wang F, Paul M, Fan D, McLean BA, Basu R, Zhang P, Shah S, Dawson JF, Pyle WG, Hazra M, Kassiri Z, Hazra S, et al. PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease. Nature Communications. 9: 5390. PMID 30568254 DOI: 10.1038/s41467-018-07812-8  0.36
2018 Chen X, Zhabyeyev P, Azad AK, Wang W, Minerath RA, DesAulniers J, Grueter CE, Murray AG, Kassiri Z, Vanhaesebroeck B, Oudit GY. Endothelial and Cardiomyocyte PI3Kβ Divergently Regulate Cardiac Remodeling in Response to Ischemic Injury. Cardiovascular Research. PMID 30496354 DOI: 10.1093/Cvr/Cvy298  0.36
2018 Jana S, Zhang H, Lopaschuk GD, Freed DH, Sergi C, Kantor PF, Oudit GY, Kassiri Z. Disparate Remodeling of the Extracellular Matrix and Proteoglycans in Failing Pediatric Versus Adult Hearts. Journal of the American Heart Association. 7: e010427. PMID 30371322 DOI: 10.1161/Jaha.118.010427  0.36
2018 Shen M, Hu M, Fedak PW, Oudit GY, Kassiri Z. Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic Aneurysm. Circulation Research. PMID 29930147 DOI: 10.1161/CIRCRESAHA.118.313181  0.36
2018 Zhabyeyev P, Das SK, Basu R, Shen M, Patel VB, Kassiri Z, Oudit GY. TIMP3 deficiency exacerbates iron-overload mediated cardiomyopathy and liver disease. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29373036 DOI: 10.1152/ajpheart.00597.2017  0.36
2017 Das SK, Zhabyeyev P, Basu R, Patel VB, Dyck JRB, Kassiri Z, Oudit GY. Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy. Bioscience Reports. PMID 29208771 DOI: 10.1042/BSR20171302  0.36
2017 Das SK, Patel VB, Basu R, Wang W, DesAulniers J, Kassiri Z, Oudit GY. Females Are Protected From Iron-Overload Cardiomyopathy Independent of Iron Metabolism: Key Role of Oxidative Stress. Journal of the American Heart Association. 6. PMID 28115312 DOI: 10.1161/JAHA.116.003456  0.36
2016 Fan D, Takawale A, Shen M, Samokhvalov V, Basu R, Patel V, Wang X, Fernandez-Patron C, Seubert JM, Oudit GY, Kassiri Z. A Disintegrin and Metalloprotease-17 Regulates Pressure Overload-Induced Myocardial Hypertrophy and Dysfunction Through Proteolytic Processing of Integrin β1. Hypertension (Dallas, Tex. : 1979). PMID 27550917 DOI: 10.1161/Hypertensionaha.116.07566  0.36
2016 Sakamuri SS, Takawale A, Basu R, Fedak PW, Freed D, Sergi C, Oudit GY, Kassiri Z. Differential impact of mechanical unloading on structural and nonstructural components of the extracellular matrix in advanced human heart failure. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 26963743 DOI: 10.1016/J.Trsl.2016.02.006  0.36
2015 Das SK, Wang W, Zhabyeyev P, Basu R, McLean B, Fan D, Parajuli N, DesAulniers J, Patel VB, Hajjar RJ, Dyck JR, Kassiri Z, Oudit GY. Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy. Scientific Reports. 5: 18132. PMID 26638758 DOI: 10.1038/srep18132  0.36
2015 Fan D, Takawale A, Shen M, Wang W, Wang X, Basu R, Oudit GY, Kassiri Z. Cardiomyocyte ADAM17 Is Essential in Post-Myocardial Infarction Repair by Regulating Angiogenesis. Circulation. Heart Failure. PMID 26136458 DOI: 10.1161/CIRCHEARTFAILURE.114.002029  0.36
2015 Das SK, DesAulniers J, Dyck JR, Kassiri Z, Oudit GY. Resveratrol mediates therapeutic hepatic effects in acquired and genetic murine models of iron-overload. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 26077449 DOI: 10.1111/liv.12893  0.36
2015 Patel VB, Takawale A, Ramprasath T, Das SK, Basu R, Grant MB, Hall DA, Kassiri Z, Oudit GY. Antagonism of angiotensin 1-7 prevents the therapeutic effects of recombinant human ACE2. Journal of Molecular Medicine (Berlin, Germany). PMID 25874965 DOI: 10.1007/S00109-015-1285-Z  0.36
2015 McLean BA, Zhabyeyev P, Patel VB, Basu R, Parajuli N, DesAulniers J, Murray AG, Kassiri Z, Vanhaesebroeck B, Oudit GY. PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart. Cardiovascular Research. 105: 292-303. PMID 25618408 DOI: 10.1093/cvr/cvv016  0.36
2014 Haddad G, Zhabyeyev P, Farhan M, Zhu LF, Kassiri Z, Rayner DC, Vanhaesebroeck B, Oudit GY, Murray AG. Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy. Blood. 124: 2142-9. PMID 25139353 DOI: 10.1182/blood-2014-02-557975  0.36
2014 Ezekowitz JA, Becher H, Belenkie I, Clark AM, Duff HJ, Friedrich MG, Haykowsky MJ, Howlett JG, Kassiri Z, Kaul P, Kim DH, Knudtson ML, Light PE, Lopaschuk GD, McAlister FA, et al. The Alberta Heart Failure Etiology and Analysis Research Team (HEART) study. Bmc Cardiovascular Disorders. 14: 91. PMID 25063541 DOI: 10.1186/1471-2261-14-91  0.36
2014 Putko BN, Wang Z, Lo J, Anderson T, Becher H, Dyck JR, Kassiri Z, Oudit GY. Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology. Plos One. 9: e99495. PMID 24923671 DOI: 10.1371/journal.pone.0099495  0.36
2014 Lee J, Shen M, Parajuli N, Oudit GY, McMurtry MS, Kassiri Z. Gender-dependent aortic remodelling in patients with bicuspid aortic valve-associated thoracic aortic aneurysm. Journal of Molecular Medicine (Berlin, Germany). 92: 939-49. PMID 24893666 DOI: 10.1007/s00109-014-1178-6  0.36
2014 Takawale A, Fan D, Basu R, Shen M, Parajuli N, Wang W, Wang X, Oudit GY, Kassiri Z. Myocardial recovery from ischemia-reperfusion is compromised in the absence of tissue inhibitor of metalloproteinase 4. Circulation. Heart Failure. 7: 652-62. PMID 24842912 DOI: 10.1161/CIRCHEARTFAILURE.114.001113  0.36
2014 Patel VB, Zhong JC, Fan D, Basu R, Morton JS, Parajuli N, McMurtry MS, Davidge ST, Kassiri Z, Oudit GY. Angiotensin-converting enzyme 2 is a critical determinant of angiotensin II-induced loss of vascular smooth muscle cells and adverse vascular remodeling. Hypertension. 64: 157-64. PMID 24799609 DOI: 10.1161/HYPERTENSIONAHA.114.03388  0.36
2014 Wang W, Patel VB, Parajuli N, Fan D, Basu R, Wang Z, Ramprasath T, Kassiri Z, Penninger JM, Oudit GY. Heterozygote loss of ACE2 is sufficient to increase the susceptibility to heart disease. Journal of Molecular Medicine (Berlin, Germany). 92: 847-58. PMID 24728465 DOI: 10.1007/S00109-014-1149-Y  0.36
2014 Fan D, Takawale A, Basu R, Patel V, Lee J, Kandalam V, Wang X, Oudit GY, Kassiri Z. Differential role of TIMP2 and TIMP3 in cardiac hypertrophy, fibrosis, and diastolic dysfunction. Cardiovascular Research. 103: 268-80. PMID 24692173 DOI: 10.1093/cvr/cvu072  0.36
2014 Mori J, Patel VB, Abo Alrob O, Basu R, Altamimi T, Desaulniers J, Wagg CS, Kassiri Z, Lopaschuk GD, Oudit GY. Angiotensin 1-7 ameliorates diabetic cardiomyopathy and diastolic dysfunction in db/db mice by reducing lipotoxicity and inflammation. Circulation. Heart Failure. 7: 327-39. PMID 24389129 DOI: 10.1161/CIRCHEARTFAILURE.113.000672  0.36
2014 Patel VB, Clarke N, Wang Z, Fan D, Parajuli N, Basu R, Putko B, Kassiri Z, Turner AJ, Oudit GY. Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: a positive feedback mechanism in the RAS. Journal of Molecular and Cellular Cardiology. 66: 167-76. PMID 24332999 DOI: 10.1016/j.yjmcc.2013.11.017  0.36
2014 Wang Z, Famulski K, Lee J, Das SK, Wang X, Halloran P, Oudit GY, Kassiri Z. TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury. Kidney International. 85: 82-93. PMID 23760282 DOI: 10.1038/Ki.2013.225  0.36
2013 Song B, Zhang ZZ, Zhong JC, Yu XY, Oudit GY, Jin HY, Lu L, Xu YL, Kassiri Z, Shen WF, Gao PJ, Zhu DL. Loss of angiotensin-converting enzyme 2 exacerbates myocardial injury via activation of the CTGF-fractalkine signaling pathway. Circulation Journal : Official Journal of the Japanese Circulation Society. 77: 2997-3006. PMID 24161906 DOI: 10.1253/circj.CJ-13-0805  0.36
2013 Wang W, McKinnie SM, Patel VB, Haddad G, Wang Z, Zhabyeyev P, Das SK, Basu R, McLean B, Kandalam V, Penninger JM, Kassiri Z, Vederas JC, Murray AG, Oudit GY. Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues. Journal of the American Heart Association. 2: e000249. PMID 23817469 DOI: 10.1161/Jaha.113.000249  0.36
2013 Patel VB, Wang Z, Fan D, Zhabyeyev P, Basu R, Das SK, Wang W, Desaulniers J, Holland SM, Kassiri Z, Oudit GY. Loss of p47phox subunit enhances susceptibility to biomechanical stress and heart failure because of dysregulation of cortactin and actin filaments. Circulation Research. 112: 1542-56. PMID 23553616 DOI: 10.1161/CIRCRESAHA.111.300299  0.36
2013 Zhabyeyev P, Gandhi M, Mori J, Basu R, Kassiri Z, Clanachan A, Lopaschuk GD, Oudit GY. Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload. Cardiovascular Research. 97: 676-85. PMID 23257023 DOI: 10.1093/cvr/cvs424  0.36
2012 Rueda-Clausen CF, Morton JS, Oudit GY, Kassiri Z, Jiang Y, Davidge ST. Effects of hypoxia-induced intrauterine growth restriction on cardiac siderosis and oxidative stress. Journal of Developmental Origins of Health and Disease. 3: 350-7. PMID 25102264 DOI: 10.1017/S2040174412000219  0.36
2012 Basu R, Fan D, Kandalam V, Lee J, Das SK, Wang X, Baldwin TA, Oudit GY, Kassiri Z. Loss of Timp3 gene leads to abdominal aortic aneurysm formation in response to angiotensin II. The Journal of Biological Chemistry. 287: 44083-96. PMID 23144462 DOI: 10.1074/Jbc.M112.425652  0.36
2012 Basu R, Lee J, Wang Z, Patel VB, Fan D, Das SK, Liu GC, John R, Scholey JW, Oudit GY, Kassiri Z. Loss of TIMP3 selectively exacerbates diabetic nephropathy. American Journal of Physiology. Renal Physiology. 303: F1341-52. PMID 22896043 DOI: 10.1152/ajprenal.00349.2012  0.36
2012 Mori J, Basu R, McLean BA, Das SK, Zhang L, Patel VB, Wagg CS, Kassiri Z, Lopaschuk GD, Oudit GY. Agonist-induced hypertrophy and diastolic dysfunction are associated with selective reduction in glucose oxidation: a metabolic contribution to heart failure with normal ejection fraction. Circulation. Heart Failure. 5: 493-503. PMID 22705769 DOI: 10.1161/CIRCHEARTFAILURE.112.966705  0.36
2012 Jin HY, Song B, Oudit GY, Davidge ST, Yu HM, Jiang YY, Gao PJ, Zhu DL, Ning G, Kassiri Z, Penninger JM, Zhong JC. ACE2 deficiency enhances angiotensin II-mediated aortic profilin-1 expression, inflammation and peroxynitrite production. Plos One. 7: e38502. PMID 22693641 DOI: 10.1371/Journal.Pone.0038502  0.36
2012 Patel VB, Bodiga S, Fan D, Das SK, Wang Z, Wang W, Basu R, Zhong J, Kassiri Z, Oudit GY. Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice. Hypertension. 59: 1195-203. PMID 22508831 DOI: 10.1161/HYPERTENSIONAHA.112.191650  0.36
2012 Patel VB, Bodiga S, Basu R, Das SK, Wang W, Wang Z, Lo J, Grant MB, Zhong J, Kassiri Z, Oudit GY. Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axis. Circulation Research. 110: 1322-35. PMID 22474255 DOI: 10.1161/Circresaha.112.268029  0.36
2012 Rey-Parra GJ, Vadivel A, Coltan L, Hall A, Eaton F, Schuster M, Loibner H, Penninger JM, Kassiri Z, Oudit GY, Thébaud B. Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury Journal of Molecular Medicine. 90: 637-647. PMID 22246130 DOI: 10.1007/S00109-012-0859-2  0.36
2011 Kandalam V, Basu R, Moore L, Fan D, Wang X, Jaworski DM, Oudit GY, Kassiri Z. Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress. Circulation. 124: 2094-105. PMID 21986284 DOI: 10.1161/CIRCULATIONAHA.111.030338  0.36
2011 Bodiga S, Zhong JC, Wang W, Basu R, Lo J, Liu GC, Guo D, Holland SM, Scholey JW, Penninger JM, Kassiri Z, Oudit GY. Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit. Cardiovascular Research. 91: 151-61. PMID 21285291 DOI: 10.1093/Cvr/Cvr036  0.36
2011 Guo D, Thiyam G, Bodiga S, Kassiri Z, Oudit GY. Uncoupling between enhanced excitation-contraction coupling and the response to heart disease: lessons from the PI3Kγ knockout murine model. Journal of Molecular and Cellular Cardiology. 50: 606-12. PMID 21276799 DOI: 10.1016/j.yjmcc.2011.01.011  0.36
2011 Zhong J, Guo D, Chen CB, Wang W, Schuster M, Loibner H, Penninger JM, Scholey JW, Kassiri Z, Oudit GY. Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2. Hypertension. 57: 314-22. PMID 21189404 DOI: 10.1161/Hypertensionaha.110.164244  0.36
2010 Guo D, Kassiri Z, Basu R, Chow FL, Kandalam V, Damilano F, Liang W, Izumo S, Hirsch E, Penninger JM, Backx PH, Oudit GY. Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress. Circulation Research. 107: 1275-89. PMID 20847309 DOI: 10.1161/Circresaha.110.229054  0.44
2010 Zhong J, Basu R, Guo D, Chow FL, Byrns S, Schuster M, Loibner H, Wang XH, Penninger JM, Kassiri Z, Oudit GY. Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction. Circulation. 122: 717-28, 18 p followi. PMID 20679547 DOI: 10.1161/Circulationaha.110.955369  0.36
2010 Kandalam V, Basu R, Abraham T, Wang X, Awad A, Wang W, Lopaschuk GD, Maeda N, Oudit GY, Kassiri Z. Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1012-23. PMID 20675565 DOI: 10.1152/Ajpheart.00246.2010  0.36
2010 Koskivirta I, Kassiri Z, Rahkonen O, Kiviranta R, Oudit GY, McKee TD, Kytö V, Saraste A, Jokinen E, Liu PP, Vuorio E, Khokha R. Mice with tissue inhibitor of metalloproteinases 4 (Timp4) deletion succumb to induced myocardial infarction but not to cardiac pressure overload. The Journal of Biological Chemistry. 285: 24487-93. PMID 20516072 DOI: 10.1074/Jbc.M110.136820  0.44
2010 Kandalam V, Basu R, Abraham T, Wang X, Soloway PD, Jaworski DM, Oudit GY, Kassiri Z. TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation. Circulation Research. 106: 796-808. PMID 20056917 DOI: 10.1161/CIRCRESAHA.109.209189  0.36
2010 Awad AE, Kandalam V, Chakrabarti S, Wang X, Penninger JM, Davidge ST, Oudit GY, Kassiri Z. Tumor necrosis factor induces matrix metalloproteinases in cardiomyocytes and cardiofibroblasts differentially via superoxide production in a PI3Kgamma-dependent manner. American Journal of Physiology. Cell Physiology. 298: C679-92. PMID 20007453 DOI: 10.1152/Ajpcell.00351.2009  0.36
2010 Oudit GY, Liu GC, Zhong J, Basu R, Chow FL, Zhou J, Loibner H, Janzek E, Schuster M, Penninger JM, Herzenberg AM, Kassiri Z, Scholey JW. Human recombinant ACE2 reduces the progression of diabetic nephropathy. Diabetes. 59: 529-38. PMID 19934006 DOI: 10.2337/Db09-1218  0.36
2009 Kassiri Z, Zhong J, Guo D, Basu R, Wang X, Liu PP, Scholey JW, Penninger JM, Oudit GY. Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction. Circulation. Heart Failure. 2: 446-55. PMID 19808375 DOI: 10.1161/Circheartfailure.108.840124  0.44
2009 Basu R, Oudit GY, Wang X, Zhang L, Ussher JR, Lopaschuk GD, Kassiri Z. Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function. American Journal of Physiology. Heart and Circulatory Physiology. 297: H2096-108. PMID 19801494 DOI: 10.1152/ajpheart.00452.2009  0.36
2009 Kassiri Z, Defamie V, Hariri M, Oudit GY, Anthwal S, Dawood F, Liu P, Khokha R. Simultaneous transforming growth factor beta-tumor necrosis factor activation and cross-talk cause aberrant remodeling response and myocardial fibrosis in Timp3-deficient heart. The Journal of Biological Chemistry. 284: 29893-904. PMID 19625257 DOI: 10.1074/Jbc.M109.028449  0.36
2009 Oudit GY, Kassiri Z, Jiang C, Liu PP, Poutanen SM, Penninger JM, Butany J. SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS European Journal of Clinical Investigation. 39: 618-625. PMID 19453650 DOI: 10.1111/J.1365-2362.2009.02153.X  0.44
2009 Kassiri Z, Oudit GY, Kandalam V, Awad A, Wang X, Ziou X, Maeda N, Herzenberg AM, Scholey JW. Loss of TIMP3 enhances interstitial nephritis and fibrosis. Journal of the American Society of Nephrology : Jasn. 20: 1223-35. PMID 19406980 DOI: 10.1681/Asn.2008050492  0.36
2008 Oudit GY, Kassiri Z, Zhou J, Liu QC, Liu PP, Backx PH, Dawood F, Crackower MA, Scholey JW, Penninger JM. Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress. Cardiovascular Research. 78: 505-14. PMID 18281373 DOI: 10.1093/Cvr/Cvn041  0.44
2007 Oudit GY, Kassiri Z. Role of PI3 kinase gamma in excitation-contraction coupling and heart disease. Cardiovascular & Hematological Disorders Drug Targets. 7: 295-304. PMID 18220729  0.36
2007 Wong DW, Oudit GY, Reich H, Kassiri Z, Zhou J, Liu QC, Backx PH, Penninger JM, Herzenberg AM, Scholey JW. Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. The American Journal of Pathology. 171: 438-51. PMID 17600118 DOI: 10.2353/Ajpath.2007.060977  0.44
2007 Oudit GY, Kassiri Z, Patel MP, Chappell M, Butany J, Backx PH, Tsushima RG, Scholey JW, Khokha R, Penninger JM. Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovascular Research. 75: 29-39. PMID 17499227 DOI: 10.1016/J.Cardiores.2007.04.007  0.44
2007 Sun M, Chen M, Dawood F, Zurawska U, Li JY, Parker T, Kassiri Z, Kirshenbaum LA, Arnold M, Khokha R, Liu PP. Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state. Circulation. 115: 1398-407. PMID 17353445 DOI: 10.1161/Circulationaha.106.643585  0.44
2006 Oudit GY, Herzenberg AM, Kassiri Z, Wong D, Reich H, Khokha R, Crackower MA, Backx PH, Penninger JM, Scholey JW. Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis. The American Journal of Pathology. 168: 1808-20. PMID 16723697 DOI: 10.2353/Ajpath.2006.051091  0.44
2005 Joza N, Oudit GY, Brown D, Bénit P, Kassiri Z, Vahsen N, Benoit L, Patel MM, Nowikovsky K, Vassault A, Backx PH, Wada T, Kroemer G, Rustin P, Penninger JM. Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy. Molecular and Cellular Biology. 25: 10261-72. PMID 16287843 DOI: 10.1128/Mcb.25.23.10261-10272.2005  0.44
2005 Kassiri Z, Oudit GY, Sanchez O, Dawood F, Mohammed FF, Nuttall RK, Edwards DR, Liu PP, Backx PH, Khokha R. Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice. Circulation Research. 97: 380-90. PMID 16037568 DOI: 10.1161/01.Res.0000178789.16929.Cf  0.44
2005 Ricci R, Eriksson U, Oudit GY, Eferl R, Akhmedov A, Sumara I, Sumara G, Kassiri Z, David JP, Bakiri L, Sasse B, Idarraga MH, Rath M, Kurz D, Theussl HC, et al. Distinct functions of junD in cardiac hypertrophy and heart failure. Genes & Development. 19: 208-13. PMID 15655111 DOI: 10.1101/Gad.327005  0.36
2002 Zobel C, Kassiri Z, Nguyen TT, Meng Y, Backx PH. Prevention of hypertrophy by overexpression of Kv4.2 in cultured neonatal cardiomyocytes. Circulation. 106: 2385-91. PMID 12403671 DOI: 10.1161/01.Cir.0000033970.22130.93  0.44
2002 Kassiri Z, Hajjar R, Backx PH. Molecular components of transient outward potassium current in cultured neonatal rat ventricular myocytes. Journal of Molecular Medicine (Berlin, Germany). 80: 351-8. PMID 12072910 DOI: 10.1007/S00109-002-0325-7  0.44
2002 Kassiri Z, Zobel C, Nguyen TT, Molkentin JD, Backx PH. Reduction of I(to) causes hypertrophy in neonatal rat ventricular myocytes. Circulation Research. 90: 578-85. PMID 11909822 DOI: 10.1161/01.Res.0000012223.86441.A1  0.44
2001 Oudit GY, Kassiri Z, Sah R, Ramirez RJ, Zobel C, Backx PH. The molecular physiology of the cardiac transient outward potassium current (I(to)) in normal and diseased myocardium. Journal of Molecular and Cellular Cardiology. 33: 851-72. PMID 11343410 DOI: 10.1006/Jmcc.2001.1376  0.44
2000 Kassiri Z, Myers R, Kaprielian R, Banijamali HS, Backx PH. Rate-dependent changes of twitch force duration in rat cardiac trabeculae: a property of the contractile system. The Journal of Physiology. 524: 221-31. PMID 10747194 DOI: 10.1111/J.1469-7793.2000.T01-3-00221.X  0.44
1999 Kaprielian R, Wickenden AD, Kassiri Z, Parker TG, Liu PP, Backx PH. Relationship between K+ channel down-regulation and [Ca2+]i in rat ventricular myocytes following myocardial infarction. The Journal of Physiology. 517: 229-45. PMID 10226162 DOI: 10.1111/J.1469-7793.1999.0229Z.X  0.44
1998 Wickenden AD, Kaprielian R, Kassiri Z, Tsoporis JN, Tsushima R, Fishman GI, Backx PH. The role of action potential prolongation and altered intracellular calcium handling in the pathogenesis of heart failure. Cardiovascular Research. 37: 312-23. PMID 9614488 DOI: 10.1016/S0008-6363(97)00256-3  0.44
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