| Year |
Citation |
Score |
| 2024 |
Shorrock HK, Aliyeva A, Frias JA, DeMeo VA, Lennon CD, DeMeo CC, Mascorro AK, Shaughnessy S, Mazdiyasni H, Cleary JD, Reddy K, Vangaveti S, Shin DS, Berglund JA. CAG repeat-selective compounds reduce abundance of expanded CAG RNAs in patient cell and murine models of SCAs. Biorxiv : the Preprint Server For Biology. PMID 39211226 DOI: 10.1101/2024.08.17.608349 |
0.728 |
|
| 2024 |
Louis JM, Frias JA, Schroader JH, Jones LA, Davey EE, Lennon CD, Chacko J, Cleary JD, Berglund JA, Reddy K. Expression levels of core spliceosomal proteins modulate the MBNL-mediated spliceopathy in DM1. Human Molecular Genetics. PMID 39180495 DOI: 10.1093/hmg/ddae125 |
0.718 |
|
| 2023 |
Shorrock HK, Lennon CD, Aliyeva A, Davey EE, DeMeo CC, Pritchard CE, Planco L, Velez JM, Mascorro-Huamancaja A, Shin DS, Cleary JD, Berglund JA. Widespread alternative splicing dysregulation occurs presymptomatically in CAG expansion spinocerebellar ataxias. Brain : a Journal of Neurology. PMID 37776516 DOI: 10.1093/brain/awad329 |
0.341 |
|
| 2023 |
Mishra SK, Hicks SM, Frias JA, Vangaveti S, Nakamori M, Cleary JD, Reddy K, Berglund JA. Quercetin selectively reduces expanded repeat RNA levels in models of myotonic dystrophy. Biorxiv : the Preprint Server For Biology. PMID 36778282 DOI: 10.1101/2023.02.02.526846 |
0.719 |
|
| 2022 |
Jenquin JR, O'Brien AP, Poukalov K, Lu Y, Frias JA, Shorrock HK, Richardson JI, Mazdiyasni H, Yang H, Huigens RW, Boykin D, Ranum LPW, Cleary JD, Wang ET, Berglund JA. Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening. Iscience. 25: 104198. PMID 35479399 DOI: 10.1016/j.isci.2022.104198 |
0.311 |
|
| 2020 |
Reddy K, Cleary JD, Berglund JA. Drug Screen Tugs at Common Thread for Repeat Disorders. Trends in Pharmacological Sciences. PMID 31926601 DOI: 10.1016/J.Tips.2019.12.004 |
0.676 |
|
| 2019 |
Reddy K, Jenquin JR, McConnell OL, Cleary JD, Richardson JI, Pinto BS, Haerle MC, Delgado E, Planco L, Nakamori M, Wang ET, Berglund JA. A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570586 DOI: 10.1073/Pnas.1901893116 |
0.72 |
|
| 2019 |
Reddy K, Jenquin JR, Cleary JD, Berglund JA. Mitigating RNA Toxicity in Myotonic Dystrophy using Small Molecules. International Journal of Molecular Sciences. 20. PMID 31426500 DOI: 10.3390/Ijms20164017 |
0.703 |
|
| 2018 |
Wang Y, Hao L, Wang H, Santostefano K, Thapa A, Cleary J, Li H, Guo X, Terada N, Ashizawa T, Xia G. Therapeutic Genome Editing for Myotonic Dystrophy Type 1 Using CRISPR/Cas9. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30274788 DOI: 10.1016/J.Ymthe.2018.09.003 |
0.31 |
|
| 2017 |
Pinto BS, Saxena T, Oliveira R, Méndez-Gómez HR, Cleary JD, Denes LT, McConnell O, Arboleda J, Xia G, Swanson MS, Wang ET. Impeding Transcription of Expanded Microsatellite Repeats by Deactivated Cas9. Molecular Cell. PMID 29056323 DOI: 10.1016/J.Molcel.2017.09.033 |
0.325 |
|
| 2014 |
Cleary JD, Ranum LP. Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders. Current Opinion in Genetics & Development. 26: 6-15. PMID 24852074 DOI: 10.1016/j.gde.2014.03.002 |
0.331 |
|
| 2013 |
Cleary JD, Ranum LP. Repeat-associated non-ATG (RAN) translation in neurological disease. Human Molecular Genetics. 22: R45-51. PMID 23918658 DOI: 10.1093/hmg/ddt371 |
0.319 |
|
| 2010 |
Cleary JD, Tomé S, López Castel A, Panigrahi GB, Foiry L, Hagerman KA, Sroka H, Chitayat D, Gourdon G, Pearson CE. Tissue- and age-specific DNA replication patterns at the CTG/CAG-expanded human myotonic dystrophy type 1 locus. Nature Structural & Molecular Biology. 17: 1079-87. PMID 20711191 DOI: 10.1038/Nsmb.1876 |
0.717 |
|
| 2010 |
López Castel A, Cleary JD, Pearson CE. Repeat instability as the basis for human diseases and as a potential target for therapy. Nature Reviews. Molecular Cell Biology. 11: 165-70. PMID 20177394 DOI: 10.1038/Nrm2854 |
0.622 |
|
| 2008 |
Libby RT, Hagerman KA, Pineda VV, Lau R, Cho DH, Baccam SL, Axford MM, Cleary JD, Moore JM, Sopher BL, Tapscott SJ, Filippova GN, Pearson CE, La Spada AR. CTCF cis-regulates trinucleotide repeat instability in an epigenetic manner: a novel basis for mutational hot spot determination. Plos Genetics. 4: e1000257. PMID 19008940 DOI: 10.1371/Journal.Pgen.1000257 |
0.643 |
|
| 2005 |
Pearson CE, Nichol Edamura K, Cleary JD. Repeat instability: mechanisms of dynamic mutations. Nature Reviews. Genetics. 6: 729-42. PMID 16205713 DOI: 10.1038/Nrg1689 |
0.622 |
|
| 2005 |
Cleary JD, Pearson CE. Replication fork dynamics and dynamic mutations: the fork-shift model of repeat instability. Trends in Genetics : Tig. 21: 272-80. PMID 15851063 DOI: 10.1016/J.Tig.2005.03.008 |
0.614 |
|
| 2003 |
Cleary JD, Pearson CE. The contribution of cis-elements to disease-associated repeat instability: clinical and experimental evidence. Cytogenetic and Genome Research. 100: 25-55. PMID 14526163 DOI: 10.1159/000072837 |
0.614 |
|
| 2002 |
Pearson CE, Tam M, Wang YH, Montgomery SE, Dar AC, Cleary JD, Nichol K. Slipped-strand DNAs formed by long (CAG)*(CTG) repeats: slipped-out repeats and slip-out junctions. Nucleic Acids Research. 30: 4534-47. PMID 12384601 DOI: 10.1093/Nar/Gkf572 |
0.57 |
|
| 2002 |
Cleary JD, Nichol K, Wang YH, Pearson CE. Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells. Nature Genetics. 31: 37-46. PMID 11967533 DOI: 10.1038/Ng870 |
0.616 |
|
| 2002 |
Panigrahi GB, Cleary JD, Pearson CE. In vitro (CTG)*(CAG) expansions and deletions by human cell extracts. The Journal of Biological Chemistry. 277: 13926-34. PMID 11832482 DOI: 10.1074/Jbc.M109761200 |
0.628 |
|
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