Gabriele Varani

Affiliations: 
1992-2001 MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 
 2001- Chemistry University of Washington, Seattle, Seattle, WA 
Area:
NMR spectroscopy to elucidate the structure and the dynamics of protein-RNA complexes
Website:
http://depts.washington.edu/chem/people/faculty/varani.html
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"Gabriele Varani"
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http://f1000.com/prime/thefaculty/member/1532918533791161

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Publications

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Ye X, Yang W, Yi S, et al. (2023) Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity. Nature Communications. 14: 701
Sharma S, Pisignano G, Merulla J, et al. (2022) A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript. Nucleic Acids Research. 50: 11331-11343
Shortridge MD, Olsen GL, Yang W, et al. (2022) A slow dynamic RNA switch regulates processing of microRNA-21. Journal of Molecular Biology. 167694
Sun YT, Varani G. (2022) Structure of the Dengue Virus RNA Promoter. Rna (New York, N.Y.)
Shortridge MD, Varani G. (2021) Efficient NMR Screening Approach to Discover Small Molecule Fragments Binding Structured RNA. Acs Medicinal Chemistry Letters. 12: 1253-1260
Sharma S, Varani G. (2020) NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication. Biochemical and Biophysical Research Communications
Chen B, Dragomir MP, Fabris L, et al. (2020) The Long Noncoding RNA CCAT2 induces chromosomal instability through BOP1 - AURKB signaling. Gastroenterology
Longo LM, Despotović D, Weil-Ktorza O, et al. (2020) Primordial emergence of a nucleic acid-binding protein via phase separation and statistical ornithine-to-arginine conversion. Proceedings of the National Academy of Sciences of the United States of America
Jones AN, Pisignano G, Pavelitz T, et al. (2020) An evolutionarily-conserved RNA structure in the functional core of the lincRNA Cyrano. Rna (New York, N.Y.)
Walker MJ, Shortridge MD, Albin DD, et al. (2020) Structure of the RNA specialized translation initiation element that recruits eIF3 to the 5'-UTR of c-Jun. Journal of Molecular Biology
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