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Thomas E. Prisinzano

Affiliations: 
University of Kansas, Lawrence, KS, United States 
Area:
Opioids, Pain, Drug abuse
Website:
http://medchem.ku.edu/thomas-prisinzano
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"Thomas Prisinzano"
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Parents

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Richard A. Glennon grad student 2000 VCU
 (Development of h5-HT(10) serotonergic ligands as potential antimigraine agents.)
Kenner C. Rice post-doc 2000-2003 NIH - NIDDK

Children

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Kevin J. Tidgewell grad student 2003-2007 University of Iowa
Anthony Lozama grad student 2010 University of Iowa
Kimberly M. Lovell grad student 2011 University of Kansas
Katherine M. Prevatt-Smith grad student 2012 University of Kansas
Tamara Vasiljevikj grad student 2013 University of Kansas
Andrew P Riley grad student 2010-2015 University of Kansas
Wayne W. Harding post-doc University of Iowa
Christopher W. Cunningham post-doc 2008-2011 University of Kansas

Collaborators

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William E. Fantegrossi collaborator 1999- University of Kansas School of Pharmacy
Trey A Ronnebaum collaborator 2016-2018 University of Kansas
BETA: Related publications

Publications

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Vu LY, Luo D, Johnson K, et al. (2024) Searching for Synthetic Opioid Rescue Agents: Identification of a Potent Opioid Agonist with Reduced Respiratory Depression. Journal of Medicinal Chemistry
Roth HG, Das M, Sulima A, et al. (2024) Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy--phenethyl-5-phenylmorphans. Molecules (Basel, Switzerland). 29
Zamarripa CA, Huskinson SL, Townsend EA, et al. (2023) Contingent administration of typical and biased kappa opioid agonists reduces cocaine and oxycodone choice in a drug vs. food choice procedure in male rhesus monkeys. Psychopharmacology
Huskinson SL, Platt DM, Smith ZR, et al. (2023) Quantification of observable behaviors following oral administration of oxycodone and nalfurafine in male rhesus monkeys. Drug and Alcohol Dependence. 252: 110953
Chambers DR, Sulima A, Luo D, et al. (2023) A MOR Antagonist with High Potency and Antagonist Efficacy among Diastereomeric C9-Alkyl-Substituted -Phenethyl-5-(3-hydroxy)phenylmorphans. Molecules (Basel, Switzerland). 28
van de Wetering R, Ewald A, Welsh S, et al. (2023) The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland). 28
Lutz JA, Sulima A, Gutman ES, et al. (2023) Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans. Molecules (Basel, Switzerland). 28
Chambers DR, Sulima A, Luo D, et al. (2022) A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists. Molecules (Basel, Switzerland). 27
Shelton CL, Meneely KM, Ronnebaum TA, et al. (2022) Rational inhibitor design for Pseudomonas aeruginosa salicylate adenylation enzyme PchD. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry
Huskinson SL, Platt DM, Zamarripa CA, et al. (2022) The G-protein biased kappa opioid agonists, triazole 1.1 and nalfurafine, produce non-uniform behavioral effects in male rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 217: 173394
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