Danny Hung-Chieh Chou, Ph.D.

Affiliations: 
2007-2011 Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
 2011-2014 Chemical Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
 2014-2020 Biochemistry University of Utah, Salt Lake City, UT 
 2020- Pediatrics Stanford University, Palo Alto, CA 
Area:
Chemical biology
Website:
https://www.dannychoulab.com
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"Danny Chou"
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SNBCP

Parents

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Ken-Tsung Wong research assistant 2003-2006 National Taiwan University
Stuart L. Schreiber grad student 2007-2011 Harvard
 (Small-molecule suppressors of cytokine-induced beta-cell apoptosis.)
Daniel G. Anderson post-doc 2011-2014 MIT
Robert S. Langer post-doc 2011-2014 MIT
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Publications

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Li W, Jacobsen MT, Park C, et al. (2024) A cysteine-specific solubilizing tag strategy enables efficient chemical protein synthesis of difficult targets. Chemical Science. 15: 3214-3222
Zhang YW, Lin NP, Guo X, et al. (2024) Omniligase-1-Mediated Phage-Peptide Library Modification and Insulin Engineering. Acs Chemical Biology
Zhang YW, Zheng N, Chou DH. (2023) Serine-mediated hydrazone ligation displaying insulin-like peptides on M13 phage pIII. Organic & Biomolecular Chemistry
Meudom R, Zhang Y, VandenBerg MA, et al. (2023) Supramolecular approaches for insulin stabilization without prolonged duration of action. Acta Pharmaceutica Sinica. B. 13: 2281-2290
Park C, Zhang Y, Jung JU, et al. (2023) Antagonistic Insulin Derivative Suppresses Insulin-Induced Hypoglycemia. Journal of Medicinal Chemistry
Clauss ZS, Meudom R, Su B, et al. (2022) Supramolecular Protein Stabilization with Zwitterionic Polypeptide-Cucurbit[7]uril Conjugates. Biomacromolecules. 24: 481-488
Laugesen SH, Chou DH, Safavi-Hemami H. (2022) Unconventional insulins from predators and pathogens. Nature Chemical Biology. 18: 688-697
Lin NP, Zheng N, Purushottam L, et al. (2022) Synthesis and Characterization of Phenylboronic Acid-Modified Insulin With Glucose-Dependent Solubility. Frontiers in Chemistry. 10: 859133
Xiong X, Blakely A, Kim JH, et al. (2022) Symmetric and asymmetric receptor conformation continuum induced by a new insulin. Nature Chemical Biology
Disotuar MM, Smith JA, Li J, et al. (2021) Facile synthesis of insulin fusion derivatives through sortase A ligation. Acta Pharmaceutica Sinica. B. 11: 2719-2725
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