Danny Hung-Chieh Chou, Ph.D.

2007-2011 Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
 2011-2014 Chemical Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
 2014-2020 Biochemistry University of Utah, Salt Lake City, UT 
 2020- Pediatrics Stanford University, Palo Alto, CA 
Chemical biology
"Danny Chou"
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Ken-Tsung Wong research assistant 2003-2006 National Taiwan University
Stuart L. Schreiber grad student 2007-2011 Harvard
 (Small-molecule suppressors of cytokine-induced beta-cell apoptosis.)
Daniel G. Anderson post-doc 2011-2014 MIT
Robert S. Langer post-doc 2011-2014 MIT
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Laugesen SH, Chou DH, Safavi-Hemami H. (2022) Unconventional insulins from predators and pathogens. Nature Chemical Biology. 18: 688-697
Lin NP, Zheng N, Purushottam L, et al. (2022) Synthesis and Characterization of Phenylboronic Acid-Modified Insulin With Glucose-Dependent Solubility. Frontiers in Chemistry. 10: 859133
Xiong X, Blakely A, Kim JH, et al. (2022) Symmetric and asymmetric receptor conformation continuum induced by a new insulin. Nature Chemical Biology
Disotuar MM, Smith JA, Li J, et al. (2021) Facile synthesis of insulin fusion derivatives through sortase A ligation. Acta Pharmaceutica Sinica. B. 11: 2719-2725
Zheng N, Christensen SB, Dowell C, et al. (2021) Discovery of Methylene Thioacetal-Incorporated α-RgIA Analogues as Potent and Stable Antagonists of the Human α9α10 Nicotinic Acetylcholine Receptor for the Treatment of Neuropathic Pain. Journal of Medicinal Chemistry
Zheng N, Christensen S, Blakely A, et al. (2020) Development of Conformationally Constrained α-RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine Receptors. Journal of Medicinal Chemistry
Xiong X, Menting JG, Disotuar MM, et al. (2020) A structurally minimized yet fully active insulin based on cone-snail venom insulin principles. Nature Structural & Molecular Biology
Xiong X, Blakely A, Karra P, et al. (2020) Novel four-disulfide insulin analog with high aggregation stability and potency. Chemical Science. 11: 195-200
Zheng N, Karra P, VandenBerg M, et al. (2019) Synthesis and Characterization of an A6-A11 Methylene Thioacetal Human Insulin Analog with Enhanced Stability. Journal of Medicinal Chemistry
Disotuar MM, Chen D, Lin NP, et al. (2019) Glucose-Responsive Insulin Through Bioconjugation Approaches. Journal of Diabetes Science and Technology. 1932296819854105
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