Brian B. Liau, Ph.D.

Affiliations: 
2013 Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
Organic synthesis
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Parents

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Elias James Corey research assistant Harvard
Matthew D. Shair grad student 2013 Harvard
 (Total syntheses of fastigiatine and the hibarimicin aglycons.)
Bradley E. Bernstein post-doc Harvard Medical School (Cell Biology Tree)
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Publications

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Kato S, Weng QY, Insco ML, et al. (2020) Gain-of-function genetic alterations of G9a drive oncogenesis. Cancer Discovery
Vinyard ME, Su C, Siegenfeld AP, et al. (2019) CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML. Nature Chemical Biology. 15: 529-539
Park Y, Koga Y, Su C, et al. (2019) A Versatile Synthetic Route to Cycloheximide and Analogues that Potently Inhibit Translation Elongation. Angewandte Chemie (International Ed. in English)
Miller TE, Liau BB, Wallace LC, et al. (2017) Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. Nature
Park Y, Liau BB. (2017) Uncovering the Cellular Target of Agelastatin A. Cell Chemical Biology. 24: 542-543
Liau BB, Sievers C, Donohue LK, et al. (2016) Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. Cell Stem Cell
Xie Q, Wu Q, Kim L, et al. (2016) RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation. The Journal of Clinical Investigation
Flavahan WA, Drier Y, Liau BB, et al. (2015) Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature
van Galen P, Viny AD, Ram O, et al. (2015) A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes. Molecular Cell
Pelish HE, Liau BB, Nitulescu II, et al. (2015) Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature. 526: 273-6
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