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Matthew D. Shair

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Organic synthesis
Website:
http://www.chem.harvard.edu/research/faculty/matthew_shair/people/shair/shair.html
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"Matthew Shair"
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Parents

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Samuel J. Danishefsky grad student 1995 Columbia
 (Total Synthesis of (±)-Dynemicin A)
Stuart L. Schreiber post-doc 1997 Harvard

Children

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Chuo Chen grad student 2001 Harvard
Mark Eric Layton grad student 2002 Harvard
Lawrence Kwan Chan grad student 2003 Harvard
Gregory Alan Korbel grad student 2003 Harvard
Allen Dennis Aloise grad student 2004 Harvard
Brian C. Goess grad student 2004 Harvard
Carl Andres Morales grad student 2004 Harvard
Henry Efrem Pelish grad student 2004 Harvard
Gojko Lalic grad student 1998-2004 Harvard
John D. Freed grad student 2005 Harvard
Oyindasola Omolara Oyelaran grad student 2005 Harvard
Ryan M. Spoering grad student 2005 Harvard
Katherine A. Mirica grad student 2004-2005 Harvard
Darryl L. Kato grad student 2007 Harvard
Evan S. Krygowski grad student 2008 Harvard
D. Ryan Anderson grad student 2009 Harvard
Kevin C. Fortner grad student 2009 Harvard
Hong M. Lee grad student 2009 Harvard
Hong Geun G. Lee grad student 2012 Harvard
Brian B. Liau grad student 2013 Harvard
Benjamin C. Milgram grad student 2013 Harvard
Brian A. Sparling grad student 2013 Harvard
Rocco Louis Policarpo grad student 2014-2019 Harvard
Craig W. Lindsley post-doc Harvard
Thomas B. Poulsen post-doc Harvard
Nick Westwood post-doc
Scott T. Phillips post-doc 2004-2006 Harvard
Anthony W.G. Burgett post-doc 2007-2010 Harvard
Olugbeminiyi Fadeyi post-doc 2012-2014 Harvard
Mahesh Vishe post-doc 2019-2020 Harvard
Robert D. Barrows post-doc 2020-2022 Harvard

Collaborators

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Publications

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Drilon A, Horan JC, Tangpeerachaikul A, et al. (2022) NVL-520 is a selective, TRK-sparing, and brain-penetrant inhibitor of ROS1 fusions and secondary resistance mutations. Cancer Discovery
Barrows RD, Jeffries DE, Vishe M, et al. (2022) Potent Uncompetitive Inhibitors of Nicotinamide -Methyltransferase (NNMT) as In Vivo Chemical Probes. Journal of Medicinal Chemistry
Decultot L, Policarpo RL, Wright BA, et al. (2020) Asymmetric Total Synthesis of C9'--Sinefungin. Organic Letters
Policarpo RL, Decultot L, May E, et al. (2019) High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT). Journal of Medicinal Chemistry
Tucker JK, Shair MD. (2019) Catalytic Allylic Oxidation to Generate Vinylogous Acyl Sulfonates from Vinyl Sulfonates. Organic Letters
Nitulescu II, Meyer SC, Wen QJ, et al. (2017) Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation. Ebiomedicine. 26: 112-125
Tahara T, Streit U, Pelish HE, et al. (2017) STAT3 Inhibitory Activity of Structurally Simplified Withaferin A Analogues. Organic Letters
Poss ZC, Ebmeier CC, Odell AT, et al. (2016) Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics. Cell Reports
Pelish HE, Liau BB, Nitulescu II, et al. (2015) Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature. 526: 273-6
Sparling BA, Tucker JK, Moebius DC, et al. (2015) Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin. Organic Letters. 17: 3398-401
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