Roberta F. Colman

1973-2009 Chemistry and Biochemistry University of Delaware, Newark, DE, United States 
enzyme active sites
"Roberta Colman"

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Thévenin AF, Zony CL, Bahnson BJ, et al. (2011) GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2. Protein Science : a Publication of the Protein Society. 20: 834-48
De Zoysa Ariyananda L, Antonopoulos C, Currier J, et al. (2011) In vitro hybridization and separation of hybrids of human adenylosuccinate lyase from wild-type and disease-associated mutant enzymes. Biochemistry. 50: 1336-46
Thévenin AF, Zony CL, Bahnson BJ, et al. (2011) Activation by phosphorylation and purification of human c-Jun N-terminal kinase (JNK) isoforms in milligram amounts. Protein Expression and Purification. 75: 138-46
Dange M, Colman RF. (2010) Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function. The Journal of Biological Chemistry. 285: 20520-5
Ariyananda Lde Z, Lee P, Antonopoulos C, et al. (2009) Biochemical and biophysical analysis of five disease-associated human adenylosuccinate lyase mutants. Biochemistry. 48: 5291-302
Hartong DT, Dange M, McGee TL, et al. (2008) Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. Nature Genetics. 40: 1230-4
Huang YC, Misquitta S, Blond SY, et al. (2008) Catalytically active monomer of glutathione S-transferase pi and key residues involved in the electrostatic interaction between subunits. The Journal of Biological Chemistry. 283: 32880-8
Sivendran S, Colman RF. (2008) Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens. Protein Science : a Publication of the Protein Society. 17: 1162-74
Hung SH, Liu AH, Pixley RA, et al. (2008) A new nonhydrolyzable reactive cGMP analogue, (Rp)-guanosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate, which targets the cGMP binding site of human platelet PDE3A. Bioorganic Chemistry. 36: 141-7
Ralat LA, Misquitta SA, Manevich Y, et al. (2008) Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin. Archives of Biochemistry and Biophysics. 474: 109-18
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