Thomas E. Smithgall

University of Pittsburgh, Pittsburgh, PA, United States 
Molecular Biology, Oncology, Biochemistry
"Thomas Smithgall"
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Weir MC, Shu ST, Patel RK, et al. (2018) Selective inhibition of the myeloid Src-family kinase Fgr potently suppresses AML cell growth in vitro and in vivo. Acs Chemical Biology
Weir MC, Hellwig S, Tan L, et al. (2017) Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth. Plos One. 12: e0181178
Tan R, Nakajima S, Wang Q, et al. (2017) Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1. Molecular Cell
Wales TE, Poe JA, Emert-Sedlak L, et al. (2016) Hydrogen Exchange Mass Spectrometry of Related Proteins with Divergent Sequences: A Comparative Study of HIV-1 Nef Allelic Variants. Journal of the American Society For Mass Spectrometry
Emert-Sedlak LA, Loughran HM, Shi H, et al. (2016) Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists. Bioorganic & Medicinal Chemistry Letters. 26: 1480-4
Roberts JM, Tarafdar S, Joseph RE, et al. (2016) Dynamics of the Tec-family Tyrosine Kinase SH3 domains. Protein Science : a Publication of the Protein Society
Grover P, Shi H, Baumgartner M, et al. (2015) Fluorescence Polarization Screening Assays for Small Molecule Allosteric Modulators of ABL Kinase Function. Plos One. 10: e0133590
Pirrone GF, Emert-Sedlak LA, Wales TE, et al. (2015) Membrane-Associated Conformation of HIV-1 Nef Investigated with Hydrogen Exchange Mass Spectrometry at a Langmuir Monolayer. Analytical Chemistry
Moroco JA, Baumgartner MP, Rust HL, et al. (2015) A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding Region. Chemical Biology & Drug Design. 86: 144-55
Bayer A, Delorme-Axford E, Sleigher C, et al. (2015) Human trophoblasts confer resistance to viruses implicated in perinatal infection. American Journal of Obstetrics and Gynecology. 212: 71.e1-8
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