Amy H. Andreotti
Affiliations: | Biochemistry, Biophysics & Molecular Biology | Iowa State University, Ames, IA, United States |
Area:
Nuclear magnetic resonance, Macromolecular structure and recognitionWebsite:
http://www.bbmb.iastate.edu/amy-andreotti/Google:
"Amy H. Andreotti"Bio:
http://www.bb.iastate.edu/andreotti/
http://www.bcb.iastate.edu/CV/Andreotti_CV.pdf
Mean distance: 6.93
Parents
Sign in to add mentor| Daniel E. Kahne | grad student | 1994 | Princeton | |
| (Part I. The effects of glycosylation on peptide backbone conformation; Part II. An NMR study of calicheamicin bound to DNA) | ||||
| Stuart L. Schreiber | post-doc | 1994-1996 | Harvard | |
Children
Sign in to add trainee| Kristine N. Brazin | grad student | 2002 | Iowa State |
| Alain T. Laederach | grad student | 2003 | Iowa State |
| Lie Min | grad student | 2008 | Iowa State |
| Andrew J. Severin | grad student | 2009 | Iowa State |
| Scott E. Boyken | grad student | 2013 | Iowa State |
| Qian Xie | grad student | 2014 | Iowa State |
| Ekaterina V. Pletneva | post-doc | Iowa State |
BETA: Related publications
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Publications
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| Rathnayake UM, Wada J, Wall VE, et al. (2025) Purification and characterization of full-length monomeric TEC family kinase, ITK. Protein Expression and Purification. 106682 |
| Moraru R, Valle-Argos B, Minton A, et al. (2024) Exploring 2-Sulfonylpyrimidine Warheads as Acrylamide Surrogates for Targeted Covalent Inhibition: A BTK Story. Journal of Medicinal Chemistry |
| Andreotti AH, Dötsch V. (2024) Allosteric regulation of kinase activity. Elife. 13 |
| Lin DY, Kueffer LE, Juneja P, et al. (2024) Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife. 12 |
| Kueffer LE, Lin DY, Amatya N, et al. (2023) Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase. Biochemistry |
| Lin DY, Kueffer LE, Juneja P, et al. (2023) Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Biorxiv : the Preprint Server For Biology |
| Lin DY, Andreotti AH. (2023) Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib. Plos One. 18: e0290872 |
| Aryal M, Lin D, Regan K, et al. (2022) The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction. Science Signaling. 15: eabn8359 |
| Brunner C, Betzler AC, Brown JR, et al. (2022) Editorial: Targeting Bruton Tyrosine Kinase. Frontiers in Cell and Developmental Biology. 10: 909655 |
| Lowe J, Joseph RE, Andreotti AH. (2022) Conformational switches that control the TEC kinase - PLCγ signaling axis. Journal of Structural Biology: X. 6: 100061 |