Michael B. Yaffe

Biology  Massachusetts Institute of Technology, Cambridge, MA, United States 
Signaling and Systems Biology
"Michael B. Yaffe"


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Himan Sternlicht grad student 1987 Case Western
 (Biophysical and biochemical properties of tubulin alpha chain by procaryotic and eucaryotic expression of a human alpha tubulin gene)
Lewis C. Cantley post-doc 1996-1998 Harvard Medical School


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Duaa H. Muhammad grad student 2002-2008 MIT
Jes Alexander grad student 2003-2008 MIT
Andrea R. Tentner grad student 2003-2009 MIT
Jonathan Rameseder grad student 2008-2014 MIT (Computational Biology Tree)
Daniel Durocher post-doc MIT (Cell Biology Tree)
Marcel A. van Vugt post-doc 2006-2008 MIT (Cell Biology Tree)
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Kang JH, Katsikis G, Li Z, et al. (2020) Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division. Nature Communications. 11: 4983
van de Kooij B, Creixell P, van Vlimmeren A, et al. (2019) Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs. Elife. 8
Miller CJ, Lou HJ, Simpson C, et al. (2019) Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output. Plos Biology. 17: e2006540
Barrett CD, Moore HB, Kong YW, et al. (2019) Tranexamic acid mediates proinflammatory and anti-inflammatory signaling via complement C5a regulation in a plasminogen activator-dependent manner. The Journal of Trauma and Acute Care Surgery. 86: 101-107
Lee MJ, Yaffe MB. (2016) Protein Regulation in Signal Transduction. Cold Spring Harbor Perspectives in Biology. 8
Lam FC, Yaffe MB. (2016) Kicking Genomic Profiling to the Curb: How Re-wiring the Phosphoproteome Can Explain Treatment Resistance in Glioma. Cancer Cell. 29: 435-6
Cannell IG, Merrick KA, Morandell S, et al. (2015) A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy. Cancer Cell
Dreaden EC, Kong YW, Morton SW, et al. (2015) Tumor-Targeted Synergistic Blockade of MAPK and PI3K From a Layer-by-Layer Nanoparticle. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Hsu AT, Barrett CD, DeBusk GM, et al. (2015) Kinetics and Role of Plasma Matrix Metalloproteinase-9 Expression in Acute Lung Injury and the Acute Respiratory Distress Syndrome. Shock (Augusta, Ga.). 44: 128-36
Rameseder J, Krismer K, Dayma Y, et al. (2015) A Multivariate Computational Method to Analyze High-Content RNAi Screening Data. Journal of Biomolecular Screening
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