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Lewis C. Cantley, Ph.D.

Affiliations: 
Systems Biology Harvard University, Cambridge, MA, United States 
Area:
PI3K and cancer metabolism
Website:
http://www.fas.harvard.edu/~biophys/Lewis_Cantley.htm
Google:
"Lewis C. Cantley"
Bio:

http://sysbio.med.harvard.edu/faculty/cantley/
http://cantley.hms.harvard.edu/
http://www.pnas.org/content/101/10/3327.full

Mean distance: 8.57
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Cross-listing: Cell Biology Tree - Evolution Tree

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Parents

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Gordon G. Hammes grad student 1975 Cornell
 (Characterization of effector binding sites on the coupling factors of oxidative phosphorylation and photophosphorylation)
Guido Guidotti post-doc 1978 Harvard

Children

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Daniel Avery Pollard research assistant 1998-2001 Harvard Medical School (Evolution Tree)
Seth J. Field grad student (Cell Biology Tree)
Bryan Ngo grad student Weil Cornell Medical College
Claudine M. Yballe grad student 2000 Harvard
Katja A. Lamia grad student 2003 Harvard
Andrew E. Elia grad student 2005 Harvard
Ji Luo grad student 2006 Harvard
Tina L. Yuan grad student 2010 Harvard
Cynthia V. Clower grad student 2011 Harvard
Peiling Tsou grad student 2011 Harvard
Shyh C. Ng grad student 2013 Harvard
Kevin D. Courtney post-doc Dana-Farber Cancer Institute (Neurotree)
Alex Toker post-doc (Cell Biology Tree)
Benjamin Turk post-doc Harvard Medical School
Matthew G. Vander Heiden post-doc Harvard Medical School
Orion D. Weiner post-doc (Neurotree)
Jihye Yun post-doc Weill Cornell Medical College
Michael B. Yaffe post-doc 1996-1998 Harvard Medical School
Jason W. Locasale post-doc 2008-2012 Harvard Medical School, Boston, USA (Cell Biology Tree)
Gina M DeNicola post-doc 2010-2015 Harvard Medical School - Beth Israel Deaconess Medical Center
Costas Lyssiotis post-doc 2010-2015 Harvard Medical School
Marcus DaSilva Goncalves post-doc 2014-2018 Weill Cornell Medicine (Neurotree)

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Publications

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Darabedian N, Ji W, Fan M, et al. (2023) Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor. Nature Chemical Biology
Stein BD, Ferrarone JR, Gardner EE, et al. (2023) LKB1-dependent regulation of TPI1 creates a divergent metabolic liability between human and mouse lung adenocarcinoma. Cancer Discovery
Johnson JL, Yaron TM, Huntsman EM, et al. (2023) An atlas of substrate specificities for the human serine/threonine kinome. Nature
Langer HT, Cantley LC, Goncalves MD. (2022) Live cold to grow old? Thermogenesis to fight cancer. Cell Research
Queiroz AL, Dantas E, Ramsamooj S, et al. (2022) Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer. Nature Communications. 13: 4633
Dibble CC, Barritt SA, Perry GE, et al. (2022) PI3K drives the de novo synthesis of coenzyme A from vitamin B5. Nature
Yoshida T, Kawabe T, Cantley LC, et al. (2022) Discovery and Characterization of a Novel Allosteric Small-Molecule Inhibitor of NADP-Dependent Malic Enzyme 1. Biochemistry. 61: 1548-1553
Taylor SR, Falcone JN, Cantley LC, et al. (2022) Developing dietary interventions as therapy for cancer. Nature Reviews. Cancer
Davdison SM, Schmidt DR, Heyman JE, et al. (2022) Pyruvate kinase M1 suppresses development and progression of prostate adenocarcinoma. Cancer Research
Gomes AP, Ilter D, Low V, et al. (2022) Altered propionate metabolism contributes to tumour progression and aggressiveness. Nature Metabolism
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