Christian Heinis

Affiliations: 
2006- MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 
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"Christian Heinis"
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Parents

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Dario Neri grad student 2000-2003 ETH Zürich
Kai Johnsson post-doc 2004-2005 EPFL
Gregory Paul Winter post-doc 2006-2008 MRC-LMB

Children

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Shiyu Chen grad student 2013 EPFL
Xudong kong post-doc EPFL
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Publications

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Danková D, Nielsen AL, Zarda A, et al. (2025) Discovery of De Novo Macrocycle Inhibitors of Histone Deacetylase 11. Jacs Au. 5: 1299-1307
Nielsen AL, Bartling CRO, Zarda A, et al. (2025) Bulk measurement of membrane permeability for random cyclic peptides in living cells to guide drug development. Angewandte Chemie (International Ed. in English). e202500493
Nielsen AL, Bognar Z, Mothukuri GK, et al. (2024) Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation. Angewandte Chemie (International Ed. in English). e202400350
Schüttel M, Will E, Sangouard G, et al. (2024) Solid-phase peptide synthesis in 384-well plates. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3555
Merz ML, Habeshian S, Li B, et al. (2023) De novo development of small cyclic peptides that are orally bioavailable. Nature Chemical Biology
Schüttel M, Heinis C. (2023) High-Density Immobilization of TCEP on Silica Beads for Efficient Disulfide Reduction and Thiol Alkylation in Peptides. Chembiochem : a European Journal of Chemical Biology. e202300592
Ji X, Nielsen AL, Heinis C. (2023) Cyclic Peptides for Drug Development. Angewandte Chemie (International Ed. in English). e202308251
Liu XY, Ji X, Heinis C, et al. (2023) Peptide-Hypervalent Iodine Reagent Chimeras: Enabling Peptide Functionalization and Macrocyclization. Angewandte Chemie (International Ed. in English). e202306036
Díaz-Perlas C, Ricken B, Farrera-Soler L, et al. (2023) High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays. Nature Communications. 14: 2774
Bognar Z, Mothukuri GK, Nielsen AL, et al. (2022) Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides. Organic & Biomolecular Chemistry. 20: 5699-5703
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