Christian Heinis
Affiliations: | 2006- | MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom |
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Parents
Sign in to add mentorDario Neri | grad student | 2000-2003 | ETH Zürich |
Kai Johnsson | post-doc | 2004-2005 | EPFL |
Gregory Paul Winter | post-doc | 2006-2008 | MRC-LMB |
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Publications
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Danková D, Nielsen AL, Zarda A, et al. (2025) Discovery of De Novo Macrocycle Inhibitors of Histone Deacetylase 11. Jacs Au. 5: 1299-1307 |
Nielsen AL, Bartling CRO, Zarda A, et al. (2025) Bulk measurement of membrane permeability for random cyclic peptides in living cells to guide drug development. Angewandte Chemie (International Ed. in English). e202500493 |
Nielsen AL, Bognar Z, Mothukuri GK, et al. (2024) Large Libraries of Structurally Diverse Macrocycles Suitable for Membrane Permeation. Angewandte Chemie (International Ed. in English). e202400350 |
Schüttel M, Will E, Sangouard G, et al. (2024) Solid-phase peptide synthesis in 384-well plates. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3555 |
Merz ML, Habeshian S, Li B, et al. (2023) De novo development of small cyclic peptides that are orally bioavailable. Nature Chemical Biology |
Schüttel M, Heinis C. (2023) High-Density Immobilization of TCEP on Silica Beads for Efficient Disulfide Reduction and Thiol Alkylation in Peptides. Chembiochem : a European Journal of Chemical Biology. e202300592 |
Ji X, Nielsen AL, Heinis C. (2023) Cyclic Peptides for Drug Development. Angewandte Chemie (International Ed. in English). e202308251 |
Liu XY, Ji X, Heinis C, et al. (2023) Peptide-Hypervalent Iodine Reagent Chimeras: Enabling Peptide Functionalization and Macrocyclization. Angewandte Chemie (International Ed. in English). e202306036 |
Díaz-Perlas C, Ricken B, Farrera-Soler L, et al. (2023) High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays. Nature Communications. 14: 2774 |
Bognar Z, Mothukuri GK, Nielsen AL, et al. (2022) Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides. Organic & Biomolecular Chemistry. 20: 5699-5703 |