Ben Shen, Ph.D.

Affiliations: 
Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Natural Product Biosynthesis
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"Ben Shen"
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Publications

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Gui C, Kalkreuter E, Lauterbach L, et al. (2024) Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate. Nature Chemical Biology
Jalali E, Wang F, Overbay BR, et al. (2024) Biochemical and Structural Studies of the Carminomycin 4--Methyltransferase DnrK. Journal of Natural Products
Steele AD, Jiang H, Pan G, et al. (2024) Discrete Acyltransferases and Thioesterases in Iso-Migrastatin and Lactimidomycin Biosynthesis. Biochemistry
Fluegel LL, Deng MR, Su P, et al. (2024) Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization. Journal of Industrial Microbiology & Biotechnology
Kalkreuter E, Kautsar SA, Yang D, et al. (2023) The Natural Products Discovery Center: Release of the First 8490 Sequenced Strains for Exploring Actinobacteria Biosynthetic Diversity. Biorxiv : the Preprint Server For Biology
Gui C, Kalkreuter E, Liu YC, et al. (2023) Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis. Nature Chemical Biology
Bhardwaj M, Cui Z, Daniel Hankore E, et al. (2023) A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220468120
Gui C, Kalkreuter E, Liu YC, et al. (2022) Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis. Journal of the American Chemical Society. 144: 20452-20462
Kalkreuter E, Shen B. (2021) MIO-containing aminomutases for α- to β-amino acids. Trends in Chemistry. 4: 91-92
Meng S, Steele AD, Yan W, et al. (2021) Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase. Nature Communications. 12: 5672
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