Katja A. Lamia, Ph.D. - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
PI3K and cancer metabolism

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio MA, Hidalgo A, ... ... Lamia K, et al. Embracing cancer complexity: Hallmarks of systemic disease. Cell. 187: 1589-1616. PMID 38552609 DOI: 10.1016/j.cell.2024.02.009  0.474
2020 Pariollaud M, Lamia KA. Cancer in the Fourth Dimension: What Is the Impact of Circadian Disruption? Cancer Discovery. 10: 1455-1464. PMID 32934020 DOI: 10.1158/2159-8290.Cd-20-0413  0.345
2020 Vaughan ME, Wallace M, Handzlik MK, Chan AB, Metallo CM, Lamia KA. Cryptochromes Suppress HIF1α in Muscles. Iscience. 23: 101338. PMID 32683313 DOI: 10.1016/J.Isci.2020.101338  0.332
2020 Porcu A, Vaughan M, Nilsson A, Arimoto N, Lamia K, Welsh DK. Vulnerability to helpless behavior is regulated by the circadian clock component CRYPTOCHROME in the mouse nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. PMID 32487727 DOI: 10.1073/Pnas.2000258117  0.317
2020 Bekki H, Duffy T, Okubo N, Olmer M, Alvarez-Garcia O, Lamia K, Kay S, Lotz M. Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis. Osteoarthritis and Cartilage. PMID 32339698 DOI: 10.1016/J.Joca.2020.04.004  0.315
2020 Chan AB, Lamia KA. Cancer, hear my battle CRY. Journal of Pineal Research. e12658. PMID 32291799 DOI: 10.1111/Jpi.12658  0.346
2020 Chan AB, Huber AL, Lamia KA. Cryptochromes modulate E2F family transcription factors. Scientific Reports. 10: 4077. PMID 32139766 DOI: 10.1038/S41598-020-61087-Y  0.334
2019 Vaughan M, Jordan SD, Duglan D, Chan AB, Afetian M, Lamia KA. Phosphorylation of CRY1 Serine 71 Alters Voluntary Activity but not Circadian Rhythms in Vivo. Journal of Biological Rhythms. 748730419858525. PMID 31258021 DOI: 10.1177/0748730419858525  0.397
2019 Duglan D, Lamia KA. Clocking In, Working Out: Circadian Regulation of Exercise Physiology. Trends in Endocrinology and Metabolism: Tem. PMID 31054802 DOI: 10.1016/J.Tem.2019.04.003  0.317
2019 Correia SP, Chan AB, Vaughan M, Zolboot N, Perea V, Huber AL, Kriebs A, Moresco JJ, Yates JR, Lamia KA. The circadian E3 ligase complex SCF targets TLK2. Scientific Reports. 9: 198. PMID 30655559 DOI: 10.1038/S41598-018-36618-3  0.388
2017 Lamia KA. Ticking time bombs: connections between circadian clocks and cancer. F1000research. 6: 1910. PMID 29152229 DOI: 10.12688/F1000Research.11770.1  0.379
2017 Henriksson E, Huber AL, Soto EK, Kriebs A, Vaughan ME, Duglan D, Chan AB, Papp SJ, Nguyen M, Afetian ME, Lamia KA. The Liver Circadian Clock Modulates Biochemical and Physiological Responses to Metformin. Journal of Biological Rhythms. 32: 345-358. PMID 28816632 DOI: 10.1177/0748730417710348  0.333
2017 Kriebs A, Jordan SD, Soto E, Henriksson E, Sandate CR, Vaughan ME, Chan AB, Duglan D, Papp SJ, Huber AL, Afetian ME, Yu RT, Zhao X, Downes M, Evans RM, ... Lamia KA, et al. Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28751364 DOI: 10.1073/Pnas.1704955114  0.344
2017 Jordan SD, Kriebs A, Vaughan M, Duglan D, Fan W, Henriksson E, Huber AL, Papp SJ, Nguyen M, Afetian M, Downes M, Yu RT, Kralli A, Evans RM, Lamia KA. CRY1/2 Selectively Repress PPARδ and Limit Exercise Capacity. Cell Metabolism. 26: 243-255.e6. PMID 28683290 DOI: 10.1016/J.Cmet.2017.06.002  0.305
2016 Huber AL, Papp SJ, Chan AB, Henriksson E, Jordan SD, Kriebs A, Nguyen M, Wallace M, Li Z, Metallo CM, Lamia KA. CRY2 and FBXL3 Cooperatively Degrade c-MYC. Molecular Cell. PMID 27840026 DOI: 10.1016/J.Molcel.2016.10.012  0.341
2016 Zhao X, Hirota T, Han X, Cho H, Chong LW, Lamia K, Liu S, Atkins AR, Banayo E, Liddle C, Yu RT, Yates JR, Kay SA, Downes M, Evans RM. Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation. Cell. 165: 1644-57. PMID 27238018 DOI: 10.1016/J.Cell.2016.05.012  0.413
2015 Henriksson E, Lamia KA. Adipose Clocks: Burning the Midnight Oil. Journal of Biological Rhythms. 30: 364-73. PMID 25926681 DOI: 10.1177/0748730415581234  0.325
2015 Papp SJ, Huber AL, Jordan SD, Kriebs A, Nguyen M, Moresco JJ, Yates JR, Lamia KA. DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. Elife. 4. PMID 25756610 DOI: 10.7554/Elife.04883  0.316
2014 Emerling BM, Hurov JB, Poulogiannis G, Choo-Wing R, Wulf GM, Shim H, Lamia KA, Rameh LE, Yuan X, Bullock A, DeNicola GM, Song J, Signoretti S, Cantley LC. Abstract NG05: Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53 null tumors Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Ng05  0.608
2013 Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Choo-Wing R, Wulf GM, Bell EL, Shim HS, Lamia KA, Rameh LE, Bellinger G, Sasaki AT, Asara JM, Yuan X, Bullock A, et al. Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors. Cell. 155: 844-57. PMID 24209622 DOI: 10.1016/J.Cell.2013.09.057  0.626
2013 Jordan SD, Lamia KA. AMPK at the crossroads of circadian clocks and metabolism. Molecular and Cellular Endocrinology. 366: 163-9. PMID 22750052 DOI: 10.1016/J.Mce.2012.06.017  0.407
2011 Lamia KA, Papp SJ, Yu RT, Barish GD, Uhlenhaut NH, Jonker JW, Downes M, Evans RM. Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Nature. 480: 552-6. PMID 22170608 DOI: 10.1038/Nature10700  0.355
2011 Sadacca LA, Lamia KA, deLemos AS, Blum B, Weitz CJ. An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice. Diabetologia. 54: 120-4. PMID 20890745 DOI: 10.1007/S00125-010-1920-8  0.308
2010 Lamia KA, Evans RM. Metabolism: Tick, tock, a beta-cell clock. Nature. 466: 571-2. PMID 20671699 DOI: 10.1038/466571A  0.333
2009 Lamia KA, Sachdeva UM, DiTacchio L, Williams EC, Alvarez JG, Egan DF, Vasquez DS, Juguilon H, Panda S, Shaw RJ, Thompson CB, Evans RM. AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. Science (New York, N.Y.). 326: 437-40. PMID 19833968 DOI: 10.1126/Science.1172156  0.414
2008 Lamia KA, Storch KF, Weitz CJ. Physiological significance of a peripheral tissue circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 105: 15172-7. PMID 18779586 DOI: 10.1073/Pnas.0806717105  0.343
2007 Yang X, Lamia KA, Evans RM. Nuclear receptors, metabolism, and the circadian clock. Cold Spring Harbor Symposia On Quantitative Biology. 72: 387-94. PMID 18419296 DOI: 10.1101/Sqb.2007.72.058  0.323
2005 Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science (New York, N.Y.). 310: 1642-6. PMID 16308421 DOI: 10.1126/Science.1120781  0.493
2004 Lamia KA, Peroni OD, Kim YB, Rameh LE, Kahn BB, Cantley LC. Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- mice. Molecular and Cellular Biology. 24: 5080-7. PMID 15143198 DOI: 10.1128/Mcb.24.11.5080-5087.2004  0.47
2003 Carricaburu V, Lamia KA, Lo E, Favereaux L, Payrastre B, Cantley LC, Rameh LE. The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation. Proceedings of the National Academy of Sciences of the United States of America. 100: 9867-72. PMID 12897244 DOI: 10.1073/Pnas.1734038100  0.489
2002 Field SJ, Lamia KA, Rameh LE, Cantley LC. Lipid research picks up speed on the slopes of Taos. Developmental Cell. 2: 407-10. PMID 11970891 DOI: 10.1016/S1534-5807(02)00150-8  0.602
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