Ginger L. Milne, Ph.D. - Publications

Affiliations: 
2002 Vanderbilt University, Nashville, TN 
Area:
free radical chemistry

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Musiek ES, Brooks JD, Joo M, Brunoldi E, Porta A, Zanoni G, Vidari G, Blackwell TS, Montine TJ, Milne GL, McLaughlin B, Morrow JD. Correction: Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the ω -3 polyunsaturated fatty acid docosahexaenoic acid. The Journal of Biological Chemistry. 294: 6657. PMID 31003972 DOI: 10.1074/jbc.AAC119.008639  0.56
2015 Kirkby NS, Reed DM, Edin ML, Rauzi F, Mataragka S, Vojnovic I, Bishop-Bailey D, Milne GL, Longhurst H, Zeldin DC, Mitchell JA, Warner TD. Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26183771 DOI: 10.1096/fj.15-275065  0.96
2015 Frederiksen BN, Seifert J, Kroehl M, Lamb MM, Milne GL, Rewers M, Norris JM. Timing of solid food introduction is associated with urinary F2-isoprostane concentrations in childhood. Pediatric Research. 78: 451-6. PMID 26083762 DOI: 10.1038/pr.2015.116  0.96
2015 Zhang Y, Desai A, Yang SY, Bae KB, Antczak MI, Fink SP, Tiwari S, Willis JE, Williams NS, Dawson DM, Wald D, Chen WD, Wang Z, Kasturi L, Larusch GA, ... ... Milne GL, et al. TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration. Science (New York, N.Y.). 348: aaa2340. PMID 26068857 DOI: 10.1126/science.aaa2340  0.96
2015 Navarro SL, White E, Kantor ED, Zhang Y, Rho J, Song X, Milne GL, Lampe PD, Lampe JW. Randomized trial of glucosamine and chondroitin supplementation on inflammation and oxidative stress biomarkers and plasma proteomics profiles in healthy humans. Plos One. 10: e0117534. PMID 25719429 DOI: 10.1371/journal.pone.0117534  0.96
2014 Ramirez CE, Shuey MM, Milne GL, Gilbert K, Hui N, Yu C, Luther JM, Brown NJ. Arg287Gln variant of EPHX2 and epoxyeicosatrienoic acids are associated with insulin sensitivity in humans. Prostaglandins & Other Lipid Mediators. 113: 38-44. PMID 25173047 DOI: 10.1016/j.prostaglandins.2014.08.001  0.96
2014 Hulgan T, Boger MS, Liao DH, McComsey GA, Wanke CA, Mangili A, Walmsley SL, McCreath H, Milne GL, Sanchez SC, Currier JS, Lake JE. Urinary eicosanoid metabolites in HIV-infected women with central obesity switching to raltegravir: an analysis from the women, integrase, and fat accumulation trial. Mediators of Inflammation. 2014: 803095. PMID 24991090 DOI: 10.1155/2014/803095  0.96
2014 El-Khuffash A, Jain A, Corcoran D, Shah PS, Hooper CW, Brown N, Poole SD, Shelton EL, Milne GL, Reese J, McNamara PJ. Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies. Pediatric Research. 76: 238-44. PMID 24941212 DOI: 10.1038/pr.2014.82  0.96
2014 Guda K, Fink SP, Milne GL, Molyneaux N, Ravi L, Lewis SM, Dannenberg AJ, Montgomery CG, Zhang S, Willis J, Wiesner GL, Markowitz SD. Inactivating mutation in the prostaglandin transporter gene, SLCO2A1, associated with familial digital clubbing, colon neoplasia, and NSAID resistance. Cancer Prevention Research (Philadelphia, Pa.). 7: 805-12. PMID 24838973 DOI: 10.1158/1940-6207.CAPR-14-0108  0.96
2014 Savage WJ, Hamilton RG, Tobian AA, Milne GL, Kaufman RM, Savage JH, Borge PD, Ness PM. Defining risk factors and presentations of allergic reactions to platelet transfusion. The Journal of Allergy and Clinical Immunology. 133: 1772-5.e9. PMID 24794681 DOI: 10.1016/j.jaci.2014.03.030  0.96
2014 Kantor ED, Lampe JW, Navarro SL, Song X, Milne GL, White E. Associations between glucosamine and chondroitin supplement use and biomarkers of systemic inflammation. Journal of Alternative and Complementary Medicine (New York, N.Y.). 20: 479-85. PMID 24738579 DOI: 10.1089/acm.2013.0323  0.96
2014 Clayton DB, Stephany HA, Ching CB, Rahman SA, Tanaka ST, Thomas JC, Pope JC, Adams MC, Brock JW, Clark PE, Hayward SW, Matusik RJ, Milne GL. F2-isoprostanes as a biomarker of oxidative stress in the mouse bladder. The Journal of Urology. 191: 1597-601. PMID 24679873 DOI: 10.1016/j.juro.2013.09.027  0.96
2014 Nicastro HL, Grubbs CJ, Margaret Juliana M, Bode AM, Kim MS, Lu Y, You M, Milne GL, Boring D, Steele VE, Lubet RA. Preventive effects of NSAIDs, NO-NSAIDs, and NSAIDs plus difluoromethylornithine in a chemically induced urinary bladder cancer model. Cancer Prevention Research (Philadelphia, Pa.). 7: 246-54. PMID 24346344 DOI: 10.1158/1940-6207.CAPR-13-0164  0.96
2014 Timmons BC, Reese J, Socrate S, Ehinger N, Paria BC, Milne GL, Akins ML, Auchus RJ, McIntire D, House M, Mahendroo M. Prostaglandins are essential for cervical ripening in LPS-mediated preterm birth but not term or antiprogestin-driven preterm ripening. Endocrinology. 155: 287-98. PMID 24189143 DOI: 10.1210/en.2013-1304  0.96
2013 Sheikh SI, Nestorov I, Russell H, O'Gorman J, Huang R, Milne GL, Scannevin RH, Novas M, Dawson KT. Tolerability and pharmacokinetics of delayed-release dimethyl fumarate administered with and without aspirin in healthy volunteers. Clinical Therapeutics. 35: 1582-1594.e9. PMID 24139424 DOI: 10.1016/j.clinthera.2013.08.009  0.96
2013 Saraswathi V, Ramnanan CJ, Wilks AW, Desouza CV, Eller AA, Murali G, Ramalingam R, Milne GL, Coate KC, Edgerton DS. Impact of hematopoietic cyclooxygenase-1 deficiency on obesity-linked adipose tissue inflammation and metabolic disorders in mice. Metabolism: Clinical and Experimental. 62: 1673-85. PMID 23987235 DOI: 10.1016/j.metabol.2013.07.007  0.96
2013 Mohebati A, Milne GL, Zhou XK, Duffield-Lillico AJ, Boyle JO, Knutson A, Bosworth BP, Kingsley PJ, Marnett LJ, Brown PH, Akpa EG, Szabo E, Dannenberg AJ. Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers. Cancer Prevention Research (Philadelphia, Pa.). 6: 646-55. PMID 23682075 DOI: 10.1158/1940-6207.CAPR-13-0083  0.96
2013 Morris PG, Zhou XK, Milne GL, Goldstein D, Hawks LC, Dang CT, Modi S, Fornier MN, Hudis CA, Dannenberg AJ. Increased levels of urinary PGE-M, a biomarker of inflammation, occur in association with obesity, aging, and lung metastases in patients with breast cancer. Cancer Prevention Research (Philadelphia, Pa.). 6: 428-36. PMID 23531446 DOI: 10.1158/1940-6207.CAPR-12-0431  0.96
2013 Hoggatt J, Mohammad KS, Singh P, Hoggatt AF, Chitteti BR, Speth JM, Hu P, Poteat BA, Stilger KN, Ferraro F, Silberstein L, Wong FK, Farag SS, Czader M, Milne GL, et al. Differential stem- and progenitor-cell trafficking by prostaglandin E2. Nature. 495: 365-9. PMID 23485965 DOI: 10.1038/nature11929  0.96
2013 Grelli KN, Palubinsky AM, Kale AC, Lizama-Manibusan BN, Stankowski JN, Milne GL, Singer R, McLaughlin B. Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation. Cns & Neurological Disorders Drug Targets. 12: 849-60. PMID 23469839  0.96
2013 Stephany HA, Strand DW, Ching CB, Tanaka ST, Milne GL, Cajaiba MM, Thomas JC, Pope JC, Adams MC, Brock JW, Hayward SW, Matusik RJ, Clayton DB. Chronic cyclic bladder over distention up-regulates hypoxia dependent pathways. The Journal of Urology. 190: 1603-9. PMID 23429070 DOI: 10.1016/j.juro.2013.02.026  0.96
2013 Milne GL, Gao B, Terry ES, Zackert WE, Sanchez SC. Measurement of F2- isoprostanes and isofurans using gas chromatography-mass spectrometry. Free Radical Biology & Medicine. 59: 36-44. PMID 23044261 DOI: 10.1016/j.freeradbiomed.2012.09.030  0.56
2012 Kirkby NS, Lundberg MH, Harrington LS, Leadbeater PD, Milne GL, Potter CM, Al-Yamani M, Adeyemi O, Warner TD, Mitchell JA. Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system. Proceedings of the National Academy of Sciences of the United States of America. 109: 17597-602. PMID 23045674 DOI: 10.1073/pnas.1209192109  0.96
2012 Hileman CO, Longenecker CT, Carman TL, Milne GL, Labbato DE, Storer NJ, White CA, McComsey GA. Elevated D-dimer is independently associated with endothelial dysfunction: a cross-sectional study in HIV-infected adults on antiretroviral therapy. Antiviral Therapy. 17: 1345-9. PMID 22878464 DOI: 10.3851/IMP2297  0.96
2012 Murali G, Milne GL, Webb CD, Stewart AB, McMillan RP, Lyle BC, Hulver MW, Saraswathi V. Fish oil and indomethacin in combination potently reduce dyslipidemia and hepatic steatosis in LDLR(-/-) mice. Journal of Lipid Research. 53: 2186-97. PMID 22847176 DOI: 10.1194/jlr.M029843  0.96
2012 Liu T, Laidlaw TM, Feng C, Xing W, Shen S, Milne GL, Boyce JA. Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2 in house dust mite-induced allergic pulmonary inflammation. Proceedings of the National Academy of Sciences of the United States of America. 109: 12692-7. PMID 22802632 DOI: 10.1073/pnas.1207816109  0.96
2012 Hileman CO, Longenecker CT, Carman TL, Milne GL, Labbato DE, Storer NJ, White CA, McComsey GA. Relationship between total bilirubin and endothelial function, inflammation and oxidative stress in HIV-infected adults on stable antiretroviral therapy Hiv Medicine. 13: 609-616. PMID 22624591 DOI: 10.1111/j.1468-1293.2012.01026.x  0.96
2012 Brantley MA, Osborn MP, Sanders BJ, Rezaei KA, Lu P, Li C, Milne GL, Cai J, Sternberg P. The short-term effects of antioxidant and zinc supplements on oxidative stress biomarker levels in plasma: a pilot investigation. American Journal of Ophthalmology. 153: 1104-9.e2. PMID 22381365 DOI: 10.1016/j.ajo.2011.12.010  0.96
2012 Boger MS, Bian A, Shintani A, Milne GL, Morrow JD, Erdem H, Mitchell V, Haas DW, Hulgan T. Sex differences in urinary biomarkers of vascular and endothelial function in HIV-infected persons receiving antiretroviral therapy. Antiviral Therapy. 17: 485-93. PMID 22293574 DOI: 10.3851/IMP1990  0.96
2012 Laidlaw TM, Kidder MS, Bhattacharyya N, Xing W, Shen S, Milne GL, Castells MC, Chhay H, Boyce JA. Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes. Blood. 119: 3790-8. PMID 22262771 DOI: 10.1182/blood-2011-10-384826  0.96
2012 Fitzgerald DW, Bezak K, Ocheretina O, Riviere C, Wright TC, Milne GL, Zhou XK, Du B, Subbaramaiah K, Byrt E, Goodwin ML, Rafii A, Dannenberg AJ. The effect of HIV and HPV coinfection on cervical COX-2 expression and systemic prostaglandin E2 levels. Cancer Prevention Research (Philadelphia, Pa.). 5: 34-40. PMID 22135046 DOI: 10.1158/1940-6207.CAPR-11-0496  0.96
2012 Brantley MA, Osborn MP, Sanders BJ, Rezaei KA, Lu P, Li C, Milne GL, Cai J, Sternberg P. Plasma biomarkers of oxidative stress and genetic variants in age-related macular degeneration. American Journal of Ophthalmology. 153: 460-467.e1. PMID 22035603 DOI: 10.1016/j.ajo.2011.08.033  0.96
2011 Milne GL, Yin H, Hardy KD, Davies SS, Roberts LJ. Isoprostane generation and function. Chemical Reviews. 111: 5973-96. PMID 21848345 DOI: 10.1021/cr200160h  0.96
2011 Brooks JD, Musiek ES, Koestner TR, Stankowski JN, Howard JR, Brunoldi EM, Porta A, Zanoni G, Vidari G, Morrow JD, Milne GL, McLaughlin B. The fatty acid oxidation product 15-A3t-isoprostane is a potent inhibitor of NFκB transcription and macrophage transformation. Journal of Neurochemistry. 119: 604-16. PMID 21838782 DOI: 10.1111/j.1471-4159.2011.07422.x  0.96
2011 Leadbeater PD, Kirkby NS, Thomas S, Dhanji AR, Tucker AT, Milne GL, Mitchell JA, Warner TD. Aspirin has little additional anti-platelet effect in healthy volunteers receiving prasugrel. Journal of Thrombosis and Haemostasis : Jth. 9: 2050-6. PMID 21794076 DOI: 10.1111/j.1538-7836.2011.04450.x  0.96
2011 Noschka E, Werre SR, Crisman MV, Thatcher CD, Milne GL, Dahlgren LA. Implications of urine F2-isoprostane metabolite concentration in horses with colic and its potential use as a predictor for surgical intervention. Equine Veterinary Journal. Supplement. 34-41. PMID 21790752 DOI: 10.1111/j.2042-3306.2011.00384.x  0.96
2011 Menon R, Fortunato SJ, Milne GL, Brou L, Carnevale C, Sanchez SC, Hubbard L, Lappas M, Drobek CO, Taylor RN. Amniotic fluid eicosanoids in preterm and term births: effects of risk factors for spontaneous preterm labor. Obstetrics and Gynecology. 118: 121-34. PMID 21691170 DOI: 10.1097/AOG.0b013e3182204eaa  0.96
2011 Rosa JS, Oliver SR, Flores RL, Ngo J, Milne GL, Zaldivar FP, Galassetti PR. Altered inflammatory, oxidative, and metabolic responses to exercise in pediatric obesity and type 1 diabetes Pediatric Diabetes. 12: 464-472. PMID 21443585 DOI: 10.1111/j.1399-5448.2010.00724.x  0.96
2011 Hardy KD, Cox BE, Milne GL, Yin H, Roberts LJ. Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo. Journal of Lipid Research. 52: 113-24. PMID 20944061 DOI: 10.1194/jlr.M010264  0.56
2010 Kleman AM, Brown JE, Zeiger SL, Hettinger JC, Brooks JD, Holt B, Morrow JD, Musiek ES, Milne GL, McLaughlin B. p66(shc)'s role as an essential mitophagic molecule in controlling neuronal redox and energetic tone. Autophagy. 6: 948-9. PMID 20724835 DOI: 10.1523/j.neurosci.6366-09.2010  0.96
2010 Oliver SR, Rosa JS, Milne GL, Pontello AM, Borntrager HL, Heydari S, Galassetti PR. Increased oxidative stress and altered substrate metabolism in obese children International Journal of Pediatric Obesity. 5: 436-444. PMID 20233149 DOI: 10.3109/17477160903545163  0.96
2010 Bain G, King CD, Rewolinski M, Schaab K, Santini AM, Shapiro D, Moran M, van de Wetering de Rooij S, Roffel AF, Schuilenga-Hut P, Milne GL, Lorrain DS, Li Y, Arruda JM, Hutchinson JH, et al. Pharmacodynamics and pharmacokinetics of AM103, a novel inhibitor of 5-lipoxygenase-activating protein (FLAP). Clinical Pharmacology and Therapeutics. 87: 437-44. PMID 20182424 DOI: 10.1038/clpt.2009.301  0.96
2010 Norman KG, Canter JA, Shi M, Milne GL, Morrow JD, Sligh JE. Cyclosporine A suppresses keratinocyte cell death through MPTP inhibition in a model for skin cancer in organ transplant recipients. Mitochondrion. 10: 94-101. PMID 19836469 DOI: 10.1016/j.mito.2009.10.001  0.96
2010 Brooks JD, Cox BE, Hardy KD, Sanchez SC, Tourino S, Koestner TH, Hyman-Howard JR, Milne GL. The Isoprostanes: Accurate Markers and Potent Mediators of Oxidant Injury in Vivo Biomarkers For Antioxidant Defense and Oxidative Damage: Principles and Practical Applications. 65-84. DOI: 10.1002/9780813814438.ch5  0.96
2009 Watters JL, Satia JA, da Costa KA, Boysen G, Collins LB, Morrow JD, Milne GL, Swenberg JA. Comparison of three oxidative stress biomarkers in a sample of healthy adults. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 14: 587-95. PMID 20001708 DOI: 10.3109/13547500903183954  0.96
2009 Wada M, Saunders TL, Morrow J, Milne GL, Walker KP, Dey SK, Brock TG, Opp MR, Aronoff DM, Smith WL. Two pathways for cyclooxygenase-2 protein degradation in vivo. The Journal of Biological Chemistry. 284: 30742-53. PMID 19758985 DOI: 10.1074/jbc.M109.052415  0.96
2009 Duffield-Lillico AJ, Boyle JO, Zhou XK, Ghosh A, Butala GS, Subbaramaiah K, Newman RA, Morrow JD, Milne GL, Dannenberg AJ. Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway. Cancer Prevention Research (Philadelphia, Pa.). 2: 322-9. PMID 19336727 DOI: 10.1158/1940-6207.CAPR-09-0005  0.96
2009 Li MH, Sanchez T, Milne GL, Morrow JD, Hla T, Ferrer F. S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor. The Journal of Urology. 181: 1347-52. PMID 19157443 DOI: 10.1016/j.juro.2008.10.140  0.96
2009 Adler DH, Phillips JA, Cogan JD, Iverson TM, Schnetz-Boutaud N, Stein JA, Brenner DA, Milne GL, Morrow JD, Boutaud O, Oates JA. The enteropathy of prostaglandin deficiency. Journal of Gastroenterology. 44: 1-7. PMID 19148786 DOI: 10.1007/s00535-008-2253-y  0.96
2009 Yin H, Cox BE, Liu W, Porter NA, Morrow JD, Milne GL. Identification of intact oxidation products of glycerophospholipids in vitro and in vivo using negative ion electrospray iontrap mass spectrometry. Journal of Mass Spectrometry : Jms. 44: 672-80. PMID 19125398 DOI: 10.1002/jms.1542  0.96
2009 Chung CP, Titova D, Oeser A, Randels M, Avalos I, Milne GL, Morrow JD, Stein CM. Oxidative stress in fibromyalgia and its relationship to symptoms. Clinical Rheumatology. 28: 435-8. PMID 19089486 DOI: 10.1007/s10067-008-1072-0  0.96
2009 Adler DH, Cogan JD, Phillips JA, Schnetz-Boutaud N, Milne GL, Iverson T, Stein JA, Brenner DA, Morrow JD, Boutaud O, Oates JA. Inherited human cPLA2α deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction (Journal of Clinical Investigation (2008) 118, (2121-2131) DOI: 10.1172/JCI30473) Journal of Clinical Investigation. 119: 2844. DOI: 10.1172/JCI30473E1  0.96
2009 Milne GL, Morrow JD. Measurement of Biological Materials Clinical and Translational Science. 69-86. DOI: 10.1016/B978-0-12-373639-0.00005-4  0.96
2008 Musiek ES, Brooks JD, Joo M, Brunoldi E, Porta A, Zanoni G, Vidari G, Blackwell TS, Montine TJ, Milne GL, McLaughlin B, Morrow JD. Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid. The Journal of Biological Chemistry. 283: 19927-35. PMID 18490445 DOI: 10.1074/jbc.M803625200  0.96
2008 Block G, Jensen CD, Morrow JD, Holland N, Norkus EP, Milne GL, Hudes M, Dalvi TB, Crawford PB, Fung EB, Schumacher L, Harmatz P. The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level. Free Radical Biology & Medicine. 45: 377-84. PMID 18455517 DOI: 10.1016/j.freeradbiomed.2008.04.005  0.96
2008 Adler DH, Cogan JD, Phillips JA, Schnetz-Boutaud N, Milne GL, Iverson T, Stein JA, Brenner DA, Morrow JD, Boutaud O, Oates JA. Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction. The Journal of Clinical Investigation. 118: 2121-31. PMID 18451993 DOI: 10.1172/JCI30473  0.96
2008 Dostalek M, Hardy KD, Milne GL, Morrow JD, Chen C, Gonzalez FJ, Gu J, Ding X, Johnson DA, Johnson JA, Martin MV, Guengerich FP. Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems. The Journal of Biological Chemistry. 283: 17147-57. PMID 18442974 DOI: 10.1074/jbc.M802447200  0.96
2008 McAnulty SR, McAnulty LS, Nieman DC, Quindry JC, Hosick PA, Hudson MH, Still L, Henson DA, Milne GL, Morrow JD, Dumke CL, Utter AC, Triplett NT, Dibarnardi A. Chronic quercetin ingestion and exercise-induced oxidative damage and inflammation. Applied Physiology, Nutrition, and Metabolism = Physiologie AppliquéE, Nutrition Et MéTabolisme. 33: 254-62. PMID 18347680 DOI: 10.1139/H07-177  0.96
2008 Milne GL, Yin H, Morrow JD. Human biochemistry of the isoprostane pathway. The Journal of Biological Chemistry. 283: 15533-7. PMID 18285331 DOI: 10.1074/jbc.R700047200  0.96
2008 Brooks JD, Milne GL, Yin H, Sanchez SC, Porter NA, Morrow JD. Formation of highly reactive cyclopentenone isoprostane compounds (A3/J3-isoprostanes) in vivo from eicosapentaenoic acid. The Journal of Biological Chemistry. 283: 12043-55. PMID 18263929 DOI: 10.1074/jbc.M800122200  0.96
2008 Long EK, Murphy TC, Leiphon LJ, Watt J, Morrow JD, Milne GL, Howard JR, Picklo MJ. Trans-4-hydroxy-2-hexenal is a neurotoxic product of docosahexaenoic (22:6; n-3) acid oxidation. Journal of Neurochemistry. 105: 714-24. PMID 18194211 DOI: 10.1111/j.1471-4159.2007.05175.x  0.96
2008 Kelly PJ, Morrow JD, Ning M, Koroshetz W, Lo EH, Terry E, Milne GL, Hubbard J, Lee H, Stevenson E, Lederer M, Furie KL. Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study. Stroke; a Journal of Cerebral Circulation. 39: 100-4. PMID 18063832 DOI: 10.1161/STROKEAHA.107.488189  0.96
2007 McAnulty SR, Hosick PA, McAnulty LS, Quindry JC, Still L, Hudson MB, Dibarnardi AN, Milne GL, Morrow JD, Austin MD. Effect of pharmacological lowering of plasma urate on exercise-induced oxidative stress. Applied Physiology, Nutrition, and Metabolism = Physiologie AppliquéE, Nutrition Et MéTabolisme. 32: 1148-55. PMID 18059589 DOI: 10.1139/H07-131  0.96
2007 Avalos I, Chung CP, Oeser A, Milne GL, Borntrager H, Morrow JD, Raggi P, Solus J, Stein CM. Aspirin therapy and thromboxane biosynthesis in systemic lupus erythematosus. Lupus. 16: 981-6. PMID 18042592 DOI: 10.1177/0961203307083313  0.56
2007 Milne GL, Yin H, Brooks JD, Sanchez S, Jackson Roberts L, Morrow JD. Quantification of F2-isoprostanes in biological fluids and tissues as a measure of oxidant stress. Methods in Enzymology. 433: 113-26. PMID 17954231 DOI: 10.1016/S0076-6879(07)33006-1  0.96
2007 Dostalek M, Brooks JD, Hardy KD, Milne GL, Moore MM, Sharma S, Morrow JD, Guengerich FP. In vivo oxidative damage in rats is associated with barbiturate response but not other cytochrome P450 inducers. Molecular Pharmacology. 72: 1419-24. PMID 17898314 DOI: 10.1124/mol.107.040238  0.96
2007 Brunoldi EM, Zanoni G, Vidari G, Sasi S, Freeman ML, Milne GL, Morrow JD. Cyclopentenone prostaglandin, 15-deoxy-Delta12,14-PGJ2, is metabolized by HepG2 cells via conjugation with glutathione. Chemical Research in Toxicology. 20: 1528-35. PMID 17854155 DOI: 10.1021/tx700231a  0.96
2007 McAnulty SR, Owens JT, McAnulty LS, Nieman DC, Morrow JD, Dumke CL, Milne GL. Ibuprofen use during extreme exercise: effects on oxidative stress and PGE2. Medicine and Science in Sports and Exercise. 39: 1075-9. PMID 17596774 DOI: 10.1249/mss.0b13e31804a8611  0.96
2007 Avalos I, Chung CP, Oeser A, Milne GL, Morrow JD, Gebretsadik T, Shintani A, Yu C, Stein CM. Oxidative stress in systemic lupus erythematosus: relationship to disease activity and symptoms. Lupus. 16: 195-200. PMID 17432105 DOI: 10.1177/0961203306075802  0.56
2007 Milne GL, Sanchez SC, Musiek ES, Morrow JD. Quantification of F2-isoprostanes as a biomarker of oxidative stress. Nature Protocols. 2: 221-6. PMID 17401357 DOI: 10.1038/nprot.2006.375  0.96
2006 Kozak KR, Milne GL, Morrow JD, Cuiffo BP. Hypertrophic osteoarthropathy pathogenesis: a case highlighting the potential role for cyclo-oxygenase-2-derived prostaglandin E2. Nature Clinical Practice. Rheumatology. 2: 452-6; quiz followin. PMID 16932737 DOI: 10.1038/ncprheum0252  0.96
2006 Milne GL, Morrow JD. Isoprostanes and related compounds: update 2006. Antioxidants & Redox Signaling. 8: 1379-84. PMID 16910785 DOI: 10.1089/ars.2006.8.1379  0.56
2006 Milne GL, Morrow JD, Picklo MJ. Elevated oxidation of docosahexaenoic acid, 22:6 (n-3), in brain regions of rats undergoing ethanol withdrawal. Neuroscience Letters. 405: 172-4. PMID 16875780 DOI: 10.1016/j.neulet.2006.06.058  0.56
2006 Reckamp KL, Krysan K, Morrow JD, Milne GL, Newman RA, Tucker C, Elashoff RM, Dubinett SM, Figlin RA. A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3381-8. PMID 16740761 DOI: 10.1158/1078-0432.CCR-06-0112  0.96
2006 Musiek ES, Breeding RS, Milne GL, Zanoni G, Morrow JD, McLaughlin B. Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration. Journal of Neurochemistry. 97: 1301-13. PMID 16638022 DOI: 10.1111/j.1471-4159.2006.03797.x  0.96
2006 Gao L, Yin H, Milne GL, Porter NA, Morrow JD. Formation of F-ring isoprostane-like compounds (F3-isoprostanes) in vivo from eicosapentaenoic acid. The Journal of Biological Chemistry. 281: 14092-9. PMID 16569632 DOI: 10.1074/jbc.M601035200  0.96
2006 Landar A, Zmijewski JW, Dickinson DA, Le Goffe C, Johnson MS, Milne GL, Zanoni G, Vidari G, Morrow JD, Darley-Usmar VM. Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species. American Journal of Physiology. Heart and Circulatory Physiology. 290: H1777-87. PMID 16387790 DOI: 10.1152/ajpheart.01087.2005  0.96
2005 Musiek ES, Yin H, Milne GL, Morrow JD. Recent advances in the biochemistry and clinical relevance of the isoprostane pathway. Lipids. 40: 987-94. PMID 16382569 DOI: 10.1007/s11745-005-1460-7  0.96
2005 Milne GL, Musiek ES, Morrow JD. F2-isoprostanes as markers of oxidative stress in vivo: an overview. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 10: S10-23. PMID 16298907 DOI: 10.1080/13547500500216546  0.96
2005 Musiek ES, Gao L, Milne GL, Han W, Everhart MB, Wang D, Backlund MG, DuBois RN, Zanoni G, Vidari G, Blackwell TS, Morrow JD. Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages. The Journal of Biological Chemistry. 280: 35562-70. PMID 16100121 DOI: 10.1074/jbc.M504785200  0.96
2005 Musiek ES, Milne GL, McLaughlin B, Morrow JD. Cyclopentenone eicosanoids as mediators of neurodegeneration: a pathogenic mechanism of oxidative stress-mediated and cyclooxygenase-mediated neurotoxicity. Brain Pathology (Zurich, Switzerland). 15: 149-58. PMID 15912888  0.96
2005 Milne GL, Gao L, Porta A, Zanoni G, Vidari G, Morrow JD. Identification of the major urinary metabolite of the highly reactive cyclopentenone isoprostane 15-A(2t)-isoprostane in vivo. The Journal of Biological Chemistry. 280: 25178-84. PMID 15878849 DOI: 10.1074/jbc.M502891200  0.56
2005 Milne GL, Musiek ES, Morrow JD. The cyclopentenone (A2/J2) isoprostanes--unique, highly reactive products of arachidonate peroxidation. Antioxidants & Redox Signaling. 7: 210-20. PMID 15650409 DOI: 10.1089/ars.2005.7.210  0.96
2005 Milne GL, Seal JR, Havrilla CM, Wijtmans M, Porter NA. Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins. Journal of Lipid Research. 46: 307-19. PMID 15547297 DOI: 10.1194/jlr.M400311-JLR200  0.96
2005 Backlund MG, Mann JR, Holla VR, Buchanan FG, Tai HH, Musiek ES, Milne GL, Katkuri S, DuBois RN. 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. The Journal of Biological Chemistry. 280: 3217-23. PMID 15542609 DOI: 10.1074/jbc.M411221200  0.96
2004 Milne GL, Zanoni G, Porta A, Sasi S, Vidari G, Musiek ES, Freeman ML, Morrow JD. The cyclopentenone product of lipid peroxidation, 15-A2t-isoprostane, is efficiently metabolized by HepG2 cells via conjugation with glutathione. Chemical Research in Toxicology. 17: 17-25. PMID 14727915 DOI: 10.1021/tx034213o  0.96
2003 Gao L, Zackert WE, Hasford JJ, Danekis ME, Milne GL, Remmert C, Reese J, Yin H, Tai HH, Dey SK, Porter NA, Morrow JD. Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase. The Journal of Biological Chemistry. 278: 28479-89. PMID 12746435 DOI: 10.1074/jbc.M303984200  0.96
2002 Fam SS, Murphey LJ, Terry ES, Zackert WE, Chen Y, Gao L, Pandalai S, Milne GL, Roberts LJ, Porter NA, Montine TJ, Morrow JD. Formation of highly reactive A-ring and J-ring isoprostane-like compounds (A4/J4-neuroprostanes) in vivo from docosahexaenoic acid. The Journal of Biological Chemistry. 277: 36076-84. PMID 12133837 DOI: 10.1074/jbc.M205638200  0.96
2002 Culbertson SM, Antunes F, Havrilla CM, Milne GL, Porter NA. Determination of the alpha-tocopherol inhibition rate constant for peroxidation in low-density lipoprotein. Chemical Research in Toxicology. 15: 870-6. PMID 12067255 DOI: 10.1021/tx020012t  0.96
2001 Milne GL, Porter NA. Separation and identification of phospholipid peroxidation products. Lipids. 36: 1265-75. PMID 11795860  0.96
Show low-probability matches.