Charles M. Thompson - Publications

University of Montana, Missoula, MT 
Organic Chemistry, Pharmaceutical Chemistry, Biochemistry

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hayes TR, Blecha JE, Chao CK, Huynh TL, VanBrocklin HD, Zinn KR, Taylor PW, Gerdes JM, Thompson CM. Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[ F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [ F]-VXS. Annals of the New York Academy of Sciences. PMID 32436233 DOI: 10.1111/nyas.14363  0.92
2020 Thompson CM, Chao CK. VGLUT substrates and inhibitors: A computational viewpoint. Biochimica Et Biophysica Acta. Biomembranes. 183175. PMID 31923412 DOI: 10.1016/j.bbamem.2020.183175  0.92
2019 Bharate SB, Chao CK, Thompson CM. Comparison of the reactivation rates of acetylcholinesterase modified by structurally different organophosphates using novel pyridinium oximes. Environmental Toxicology and Pharmacology. 71: 103218. PMID 31302432 DOI: 10.1016/j.etap.2019.103218  0.92
2019 Hayes TR, Blecha JE, Thompson CM, Gerdes JM, VanBrocklin HF. Divergent synthesis of organophosphate [C]VX- and [C]Sarin-surrogates from a common set of starting materials. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 151: 182-186. PMID 31202183 DOI: 10.1016/j.apradiso.2019.05.033  0.68
2019 Thompson CM, Gerdes JM. Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures. Neurobiology of Disease. PMID 31022458 DOI: 10.1016/j.nbd.2019.04.011  0.68
2018 Hayes TR, Thompson CM, Blecha JE, Gerdes JM, VanBrocklin HF. Radiosynthesis of O-(1-[ F]fluoropropan-2-yl)-O-(4-nitrophenyl)methylphosphonate: a novel PET tracer surrogate of sarin. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 30347484 DOI: 10.1002/jlcr.3688  0.68
2018 Chao CK, Balasubramanian N, Gerdes JM, Thompson CM. The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE. Chemico-Biological Interactions. PMID 29920286 DOI: 10.1016/j.cbi.2018.06.019  0.92
2017 Neumann KD, Thompson CM, Blecha JE, Gerdes JM, VanBrocklin HF. An Improved Radiosynthesis of O-(2-[(18) F]Fluoroethyl)-O-(p-nitrophenyl)methylphosphonate: A First-in-Class Cholinesterase PET Tracer. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 28406525 DOI: 10.1002/jlcr.3511  0.68
2016 Chao CK, Ahmed SK, Gerdes JM, Thompson CM. The Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-nitrophenyl)methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases. Chemical Research in Toxicology. PMID 27551891 DOI: 10.1021/acs.chemrestox.6b00160  0.92
2016 Berkman CE, Fernandez EJ, Thompson CM, Pavkovic SF. Structure of 19-methylstrychninium (S)-{S-[(R)-1,2-di(ethoxycarbonyl)ethyl] O-methyl phosphorodithioate} Acta Crystallographica Section C: Crystal Structure Communications. 49: 554-556. DOI: 10.1107/S0108270192007637  0.68
2014 Belabassi Y, Chao CK, Holly R, George KM, Nagy JO, Thompson CM. Preparation and characterization of diethoxy- and monoethoxy phosphylated ('aged') serine haptens and use in the production of monoclonal antibodies. Chemico-Biological Interactions. 223: 134-140. PMID 25261769 DOI: 10.1016/j.cbi.2014.09.010  0.68
2014 Hitt DM, Belabassi Y, Suhy J, Berkman CE, Thompson CM. Chemoenzymatic resolution of rac-malathion. Tetrahedron, Asymmetry. 25: 529-533. PMID 24839353 DOI: 10.1016/j.tetasy.2014.02.013  0.68
2014 James SL, Ahmed SK, Murphy S, Braden MR, Belabassi Y, VanBrocklin HF, Thompson CM, Gerdes JM. A novel fluorine-18 β-fluoroethoxy organophosphate positron emission tomography imaging tracer targeted to central nervous system acetylcholinesterase. Acs Chemical Neuroscience. 5: 519-24. PMID 24716794 DOI: 10.1021/cn500024c  0.68
2014 Prins JM, Chao CK, Jacobson SM, Thompson CM, George KM. Oxidative stress resulting from exposure of a human salivary gland cells to paraoxon: an in vitro model for organophosphate oral exposure. Toxicology in Vitro : An International Journal Published in Association With Bibra. 28: 715-21. PMID 24486155 DOI: 10.1016/j.tiv.2014.01.009  0.68
2014 Carrigan CN, Patel SA, Cox HD, Bolstad ES, Gerdes JM, Smith WE, Bridges RJ, Thompson CM. The development of benzo- and naphtho-fused quinoline-2,4-dicarboxylic acids as vesicular glutamate transporter (VGLUT) inhibitors reveals a possible role for neuroactive steroids. Bioorganic & Medicinal Chemistry Letters. 24: 850-4. PMID 24424130 DOI: 10.1016/j.bmcl.2013.12.086  0.68
2013 Kaleem Ahmed S, Belabassi Y, Sankaranarayanan L, Chao CK, Gerdes JM, Thompson CM. Synthesis and anti-acetylcholinesterase properties of novel β- and γ-substituted alkoxy organophosphonates. Bioorganic & Medicinal Chemistry Letters. 23: 2048-51. PMID 23453838 DOI: 10.1016/j.bmcl.2013.02.010  0.68
2011 Ahmed SK, Etoga JL, Patel SA, Bridges RJ, Thompson CM. Use of the hydantoin isostere to produce inhibitors showing selectivity toward the vesicular glutamate transporter versus the obligate exchange transporter system x(c)(-). Bioorganic & Medicinal Chemistry Letters. 21: 4358-62. PMID 21669531 DOI: 10.1016/j.bmcl.2011.05.018  0.48
2010 Prins JM, Brooks DM, Thompson CM, Lurie DI. Chronic low-level Pb exposure during development decreases the expression of the voltage-dependent anion channel in auditory neurons of the brainstem. Neurotoxicology. 31: 662-73. PMID 20797405 DOI: 10.1016/j.neuro.2010.08.004  0.68
2010 Bharate SB, Prins JM, George KM, Thompson CM. Thionate versus Oxon: comparison of stability, uptake, and cell toxicity of ((14)CH(3)O)(2)-labeled methyl parathion and methyl paraoxon with SH-SY5Y cells. Journal of Agricultural and Food Chemistry. 58: 8460-6. PMID 20590114 DOI: 10.1021/jf100976v  0.68
2010 Proskocil BJ, Bruun DA, Thompson CM, Fryer AD, Lein PJ. Organophosphorus pesticides decrease M2 muscarinic receptor function in guinea pig airway nerves via indirect mechanisms. Plos One. 5: e10562. PMID 20479945 DOI: 10.1371/journal.pone.0010562  0.68
2010 Ye R, Rhoderick JF, Thompson CM, Bridges RJ. Functional expression, purification and high sequence coverage mass spectrometric characterization of human excitatory amino acid transporter EAAT2. Protein Expression and Purification. 74: 49-59. PMID 20399272 DOI: 10.1016/j.pep.2010.04.006  0.48
2010 Etoga JL, Ahmed SK, Patel S, Bridges RJ, Thompson CM. Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system x(c)(-) over the vesicular glutamate transporter. Bioorganic & Medicinal Chemistry Letters. 20: 2680-3. PMID 20303751 DOI: 10.1016/j.bmcl.2009.10.020  0.48
2010 Guo L, Suarez AI, Braden MR, Gerdes JM, Thompson CM. Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates. Bioorganic & Medicinal Chemistry Letters. 20: 1194-7. PMID 20034789 DOI: 10.1016/j.bmcl.2009.12.007  0.68
2010 Bharate SB, Guo L, Reeves TE, Cerasoli DM, Thompson CM. Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase. Bioorganic & Medicinal Chemistry. 18: 787-94. PMID 20005727 DOI: 10.1016/j.bmc.2009.11.052  0.68
2010 Guo L, Suarez AI, Thompson CM. Inactivation of acetylcholinesterase by various fluorophores. Journal of Enzyme Inhibition and Medicinal Chemistry. 25: 116-20. PMID 19842944 DOI: 10.3109/14756360903027816  0.6
2009 Mullins JE, Etoga JL, Gajewski M, Degraw JI, Thompson CM. Unexpected Formation of Highly Functionalized Dihydropyrans via Addition-Cyclization Reactions Between Dimethyl Oxoglutaconate and α,β-Unsaturated Hydrazones. Tetrahedron Letters. 50: 2298-2300. PMID 20161237 DOI: 10.1016/j.tetlet.2009.02.180  0.68
2009 Bharate SB, Guo L, Reeves TE, Cerasoli DM, Thompson CM. New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase. Bioorganic & Medicinal Chemistry Letters. 19: 5101-4. PMID 19640713 DOI: 10.1016/j.bmcl.2009.07.035  0.68
2009 Li B, Schopfer LM, Grigoryan H, Thompson CM, Hinrichs SH, Masson P, Lockridge O. Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: a new motif for binding to proteins that have no active site serine. Toxicological Sciences : An Official Journal of the Society of Toxicology. 107: 144-55. PMID 18930948 DOI: 10.1093/toxsci/kfn211  0.68
2008 Ding SJ, Carr J, Carlson JE, Tong L, Xue W, Li Y, Schopfer LM, Li B, Nachon F, Asojo O, Thompson CM, Hinrichs SH, Masson P, Lockridge O. Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin Chemical Research in Toxicology. 21: 1787-1794. PMID 18707141 DOI: 10.1021/tx800144z  0.68
2008 Cox HD, Chao CK, Patel SA, Thompson CM. Efficient digestion and mass spectral analysis of vesicular glutamate transporter 1: a recombinant membrane protein expressed in yeast. Journal of Proteome Research. 7: 570-8. PMID 18179165 DOI: 10.1021/pr070452b  0.68
2007 Patel SA, Nagy JO, Bolstad ED, Gerdes JM, Thompson CM. Tetrapeptide inhibitors of the glutamate vesicular transporter (VGLUT). Bioorganic & Medicinal Chemistry Letters. 17: 5125-8. PMID 17662605 DOI: 10.1016/j.bmcl.2007.07.006  0.68
2006 Santos SS, Gibson GE, Cooper AJ, Denton TT, Thompson CM, Bunik VI, Alves PM, Sonnewald U. Inhibitors of the alpha-ketoglutarate dehydrogenase complex alter [1-13C]glucose and [U-13C]glutamate metabolism in cerebellar granule neurons. Journal of Neuroscience Research. 83: 450-8. PMID 16416424 DOI: 10.1002/jnr.20749  0.68
2005 Thompson CM, Davis E, Carrigan CN, Cox HD, Bridges RJ, Gerdes JM. Inhibitor of the glutamate vesicular transporter (VGLUT). Current Medicinal Chemistry. 12: 2041-56. PMID 16101493 DOI: 10.2174/0929867054637635  0.68
2005 Bunik VI, Denton TT, Xu H, Thompson CM, Cooper AJ, Gibson GE. Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells. Biochemistry. 44: 10552-61. PMID 16060664 DOI: 10.1021/bi0503100  0.68
2005 Thullbery MD, Cox HD, Schule T, Thompson CM, George KM. Differential localization of acetylcholinesterase in neuronal and non-neuronal cells. Journal of Cellular Biochemistry. 96: 599-610. PMID 16052514 DOI: 10.1002/jcb.20530  0.68
2004 Coughenour HD, Spaulding RS, Thompson CM. The synaptic vesicle proteome: a comparative study in membrane protein identification. Proteomics. 4: 3141-55. PMID 15378707 DOI: 10.1002/pmic.200300817  0.68
2004 Tongcharoensirikul P, Suarez AI, Voelker T, Thompson CM. Stereoselective addition of dimethyl thiophosphite to imines. The Journal of Organic Chemistry. 69: 2322-6. PMID 15049625 DOI: 10.1021/jo035707t  0.6
2003 George KM, Schule T, Sandoval LE, Jennings LL, Taylor P, Thompson CM. Differentiation between acetylcholinesterase and the organophosphate-inhibited form using antibodies and the correlation of antibody recognition with reactivation mechanism and rate. The Journal of Biological Chemistry. 278: 45512-8. PMID 12933813 DOI: 10.1074/jbc.M304781200  0.68
2003 Doorn JA, Thompson CM, Christner RB, Richardson RJ. Stereoselective inactivation of Torpedo californica acetylcholinesterase by isomalathion: inhibitory reactions with (1R)- and (1S)-isomers proceed by different mechanisms. Chemical Research in Toxicology. 16: 958-65. PMID 12924923 DOI: 10.1021/tx030026e  0.68
2002 Carrigan CN, Bartlett RD, Esslinger CS, Cybulski KA, Tongcharoensirikul P, Bridges RJ, Thompson CM. Synthesis and in vitro pharmacology of substituted quinoline-2,4-dicarboxylic acids as inhibitors of vesicular glutamate transport. Journal of Medicinal Chemistry. 45: 2260-76. PMID 12014964 DOI: 10.1021/jm010261z  0.68
2002 George KM, Montgomery MA, Sandoval LE, Thompson CM. Examination of cross-antigenicity of acetylcholinesterase and butyrylcholinesterase using anti-acetylcholinesterase antibodies. Toxicology Letters. 126: 99-105. PMID 11751014 DOI: 10.1016/S0378-4274(01)00449-0  0.68
2001 Denton TT, Thompson CM, Cooper AJ. Analysis of conformationally restricted alpha-ketoglutarate analogues as substrates of dehydrogenases and aminotransferases. Analytical Biochemistry. 298: 265-74. PMID 11700982 DOI: 10.1006/abio.2001.5366  0.68
2001 Doorn JA, Schall M, Gage DA, Talley TT, Thompson CM, Richardson RJ. Identification of butyrylcholinesterase adducts after inhibition with isomalathion using mass spectrometry: difference in mechanism between (1R)- and (1S)-stereoisomers. Toxicology and Applied Pharmacology. 176: 73-80. PMID 11601883 DOI: 10.1006/taap.2001.9279  0.68
2001 Doorn JA, Talley TT, Thompson CM, Richardson RJ. Probing the active sites of butyrylcholinesterase and cholesterol esterase with isomalathion: conserved stereoselective inactivation of serine hydrolases structurally related to acetylcholinesterase. Chemical Research in Toxicology. 14: 807-13. PMID 11453726 DOI: 10.1021/tx015501s  0.68
2000 Doorn JA, Gage DA, Schall M, Talley TT, Thompson CM, Richardson RJ. Inhibition of acetylcholinesterase by (1S,3S)-isomalathion proceeds with loss of thiomethyl: kinetic and mass spectral evidence for an unexpected primary leaving group. Chemical Research in Toxicology. 13: 1313-20. PMID 11123973 DOI: 10.1021/tx000184v  0.68
2000 Saltmarsh JR, Boyd AE, Rodriguez OP, Radić Z, Taylor P, Thompson CM. Synthesis of fluorescent probes directed to the active site gorge of acetylcholinesterase. Bioorganic & Medicinal Chemistry Letters. 10: 1523-6. PMID 10915041 DOI: 10.1016/S0960-894X(00)00275-4  0.68
1999 Carrigan CN, Esslinger CS, Bartlett RD, Bridges RJ, Thompson CM. Quinoline-2,4-dicarboxylic acids: synthesis and evaluation as inhibitors of the glutamate vesicular transport system. Bioorganic & Medicinal Chemistry Letters. 9: 2607-12. PMID 10498218 DOI: 10.1016/S0960-894X(99)00444-8  0.68
1999 Jianmongkol S, Marable BR, Berkman CE, Talley TT, Thompson CM, Richardson RJ. Kinetic evidence for different mechanisms of acetylcholinesterase inhibition by (1R)- and (1S)-stereoisomers of isomalathion. Toxicology and Applied Pharmacology. 155: 43-53. PMID 10036217 DOI: 10.1006/taap.1998.8608  0.68
1999 Hamed O, Henry PM, Thompson C. Palladium(II)-catalyzed exchange and isomerization reactions. 17. Exchange of chiral allyl alcohols with hydroxide, methoxide, and phenyl at high [Cl-]. Stereochemistry of the Wacker reaction Journal of Organic Chemistry. 64: 7745-7750. DOI: 10.1021/jo9906274  0.68
1998 Esslinger CS, Koch HP, Kavanaugh MP, Philips DP, Chamberlin AR, Thompson CM, Bridges RJ. Structural determinants of substrates and inhibitors: probing glutamate transporters with 2,4-methanopyrrolidine-2,4-dicarboxylate. Bioorganic & Medicinal Chemistry Letters. 8: 3101-6. PMID 9873684 DOI: 10.1016/S0960-894X(98)00560-5  0.68
1992 Bierer DE, O'Connell JF, Parquette JR, Thompson CM, Rapoport H. Regiospecific synthesis of the aminoimidazoquinoxaline (IQx) mutagens from cooked foods Journal of Organic Chemistry. 57: 1390-1405.  0.68
1986 Rapoport H, Waterhouse AL, Thompson CM, O'Connell JF. Synthesis and radiolabeling of heterocyclic food mutagens. Environmental Health Perspectives. 67: 41-5. PMID 3757958  0.68
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