Auinash Kalsotra, Ph.D. - Publications

Affiliations: 
2005 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Molecular Biology, Neuroscience Biology, Pharmacology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Goo YH, Plakkal Ayyappan J, Cheeran FD, Bangru S, Saha PK, Baar P, Schulz S, Lydic TA, Spengler B, Wagner AH, Kalsotra A, Yechoor VK, Paul A. Lipid droplet-associated hydrolase mobilizes stores of liver X receptor sterol ligands and protects against atherosclerosis. Nature Communications. 15: 6540. PMID 39095402 DOI: 10.1038/s41467-024-50949-y  0.747
2024 Bangru S, Chen J, Baker N, Das D, Chembazhi UV, Derham JM, Chorghade S, Arif W, Alencastro F, Duncan AW, Carstens RP, Kalsotra A. ESRP2-microRNA-122 axis directs the postnatal onset of liver polyploidization and maturation. Biorxiv : the Preprint Server For Biology. PMID 39026848 DOI: 10.1101/2024.07.06.602336  0.787
2024 Wang Y, Chembazhi UV, Yee D, Chen S, Ji J, Wang Y, Nguyen KL, Lin P, Ratti A, Hess R, Qiao H, Ko C, Yang J, Kalsotra A, Mei W. PTBP1 mediates Sertoli cell actin cytoskeleton organization by regulating alternative splicing of actin regulators. Biorxiv : the Preprint Server For Biology. PMID 38915624 DOI: 10.1101/2024.06.12.598725  0.781
2024 Adesanya O, Das D, Kalsotra A. Emerging roles of RNA-binding proteins in fatty liver disease. Wiley Interdisciplinary Reviews. Rna. 15: e1840. PMID 38613185 DOI: 10.1002/wrna.1840  0.347
2023 Piersma SJ, Bangru S, Yoon J, Liu TW, Yang L, Hsieh CS, Plougastel-Douglas B, Kalsotra A, Yokoyama WM. NK cell expansion requires HuR and mediates control of solid tumors and long-term virus infection. The Journal of Experimental Medicine. 220. PMID 37698554 DOI: 10.1084/jem.20231154  0.719
2023 Derham JM, Kalsotra A. The discovery, function, and regulation of epithelial splicing regulatory proteins (ESRP) 1 and 2. Biochemical Society Transactions. PMID 37314029 DOI: 10.1042/BST20221124  0.306
2023 Arif W, Mathur B, Saikali MF, Chembazhi UV, Toohill K, Song YJ, Hao Q, Karimi S, Blue SM, Yee BA, Van Nostrand EL, Bangru S, Guzman G, Yeo GW, Prasanth KV, ... ... Kalsotra A, et al. Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death. Nature Communications. 14: 551. PMID 36759613 DOI: 10.1038/s41467-023-35932-3  0.799
2023 Chembazhi UV, Tung WS, Hwang H, Wang Y, Lalwani A, Nguyen KL, Bangru S, Yee D, Chin K, Yang J, Kalsotra A, Mei W. PTBP1 controls intestinal epithelial regeneration through post-transcriptional regulation of gene expression. Nucleic Acids Research. PMID 36744439 DOI: 10.1093/nar/gkad042  0.781
2022 Sonam S, Bangru S, Perry KJ, Chembazhi UV, Kalsotra A, Henry JJ. Cellular and molecular profiles of larval and adult Xenopus corneal epithelia resolved at the single-cell level. Developmental Biology. PMID 36049533 DOI: 10.1016/j.ydbio.2022.08.007  0.788
2022 Peng J, Serrano G, Traniello IM, Calleja-Cervantes ME, Chembazhi UV, Bangru S, Ezponda T, Rodriguez-Madoz JR, Kalsotra A, Prosper F, Ochoa I, Hernaez M. SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes. Communications Biology. 5: 351. PMID 35414121 DOI: 10.1038/s42003-022-03319-7  0.785
2021 Mathur B, Shajahan A, Arif W, Chen Q, Hand NJ, Abramowitz LK, Schoonjans K, Rader DJ, Kalsotra A, Hanover JA, Azadi P, Anakk S. Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver. Science Advances. 7. PMID 33883138 DOI: 10.1126/sciadv.abf4865  0.805
2021 Chembazhi UV, Bangru S, Hernaez M, Kalsotra A. Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver. Genome Research. PMID 33649154 DOI: 10.1101/gr.267013.120  0.809
2020 Eagleman DE, Zhu J, Liu DC, Seimetz J, Kalsotra A, Tsai NP. Unbiased Proteomic Screening Identifies a Novel Role for the E3 Ubiquitin Ligase Nedd4-2 in Translational Suppression During ER Stress. Journal of Neurochemistry. PMID 33064840 DOI: 10.1111/jnc.15219  0.779
2020 Mathur B, Arif W, Patton ME, Faiyaz R, Liu J, Yeh J, Harpavat S, Schoonjans K, Kalsotra A, Wheatley AM, Anakk S. Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis. Jhep Reports : Innovation in Hepatology. 2: 100140. PMID 32875282 DOI: 10.1016/j.jhepr.2020.100140  0.781
2020 Sun Q, Hao Q, Lin YC, Song YJ, Bangru S, Arif W, Tripathi V, Zhang Y, Cho JH, Freier SM, Jenkins L, Ma J, Yoon JH, Kalsotra A, Lal A, et al. Antagonism between Splicing and Microprocessor complex Dictates the Serum-induced Processing of Lnc-MIRHG for Efficient Cell Cycle Re-entry. Rna (New York, N.Y.). PMID 32675111 DOI: 10.1261/Rna.075309.120  0.803
2020 Wen Y, Chen J, Li J, Arif W, Kalsotra A, Irudayaraj J. Effect of PFOA on DNA Methylation and Alternative Splicing in Mouse Liver. Toxicology Letters. PMID 32320774 DOI: 10.1016/J.Toxlet.2020.04.012  0.809
2020 Srivastava I, Misra SK, Bangru S, Boateng K, Soares JANT, Schwartz-Duval AS, Kalsotra A, Pan D. Complementary Oligonucleotide Conjugated Multi-Color Carbon Dots for Intracellular Recognition of Biological Events. Acs Applied Materials & Interfaces. PMID 32182420 DOI: 10.1021/Acsami.0C02463  0.715
2020 Misra C, Bangru S, Lin F, Lam K, Koenig SN, Lubbers ER, Hedhli J, Murphy NP, Parker DJ, Dobrucki LW, Cooper TA, Tajkhorshid E, Mohler PJ, Kalsotra A. Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy. Developmental Cell. PMID 32109384 DOI: 10.1016/J.Devcel.2020.01.037  0.787
2020 Bangru S, Kalsotra A. Cellular and molecular basis of liver regeneration. Seminars in Cell & Developmental Biology. PMID 31980376 DOI: 10.1016/J.Semcdb.2019.12.004  0.778
2020 Hyun J, Sun Z, Ahmadi AR, Bangru S, Chembazhi UV, Du K, Chen T, Tsukamoto H, Rusyn I, Kalsotra A, Diehl AM. Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis. The Journal of Clinical Investigation. PMID 31945016 DOI: 10.1172/Jci132691  0.799
2019 Lee J, Bai Y, Chembazhi UV, Peng S, Yum K, Luu LM, Hagler LD, Serrano JF, Chan HYE, Kalsotra A, Zimmerman SC. Intrinsically cell-penetrating multivalent and multitargeting ligands for myotonic dystrophy type 1. Proceedings of the National Academy of Sciences of the United States of America. PMID 30975744 DOI: 10.1073/Pnas.1820827116  0.788
2018 Seimetz J, Arif W, Bangru S, Hernaez M, Kalsotra A. Cell-type specific polysome profiling from mammalian tissues. Methods (San Diego, Calif.). PMID 30500367 DOI: 10.1016/J.Ymeth.2018.11.015  0.779
2018 Bangru S, Arif W, Seimetz J, Bhate A, Chen J, Rashan EH, Carstens RP, Anakk S, Kalsotra A. Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration. Nature Structural & Molecular Biology. PMID 30250226 DOI: 10.1038/S41594-018-0129-2  0.792
2018 Misra C, Lin F, Kalsotra A. Deregulation of RNA Metabolism in Microsatellite Expansion Diseases. Advances in Neurobiology. 20: 213-238. PMID 29916021 DOI: 10.1007/978-3-319-89689-2_8  0.372
2018 Jaiswal M, Haelterman NA, Sandoval H, Xiong B, Donti T, Kalsotra A, Yamamoto S, Cooper TA, Graham BH, Bellen HJ. Correction: Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress. Plos Biology. 16: e1002622. PMID 29509758 DOI: 10.1371/Journal.Pbio.1002622  0.505
2018 MISRA C, BANGRU S, PARKER DJ, KOENIG S, LUBBERS E, HEDHLI J, COOPER TA, DOBRUCKI WL, MOHLER P, KALSOTRA A. Abstract 520: Overexpression of a Non-muscle RBFOX2 Splice Isoform Induce Cardiac Arrhythmias in Myotonic Dystrophy Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.520  0.758
2018 Goo Y, Lee I, Lydic TA, Bangru S, Saha P, Kalsotra A, Chan LC, Paul A. Abstract 447: Lipid Droplet Associated Hydrolase (LDAH) Impacts Oxysterol Metabolism and Prevents Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.447  0.721
2017 Liu DC, Seimetz J, Lee KY, Kalsotra A, Chung HJ, Lu H, Tsai NP. Mdm2 mediates FMRP- and Gp1 mGluR-dependent protein translation and neural network activity. Human Molecular Genetics. 26: 3895-3908. PMID 29016848 DOI: 10.1093/Hmg/Ddx276  0.769
2017 Aguero T, Jin Z, Chorghade S, Kalsotra A, King ML, Yang J. Maternal dead-end 1 promotes translation of nanos1 through binding the eIF3 complex. Development (Cambridge, England). PMID 28870987 DOI: 10.1242/Dev.152611  0.396
2017 Skariah G, Seimetz J, Norsworthy M, Lannom MC, Kenny PJ, Elrakhawy M, Forsthoefel C, Drnevich J, Kalsotra A, Ceman S. Mov10 suppresses retroelements and regulates neuronal development and function in the developing brain. Bmc Biology. 15: 54. PMID 28662698 DOI: 10.1186/S12915-017-0387-1  0.794
2017 Chorghade S, Seimetz J, Emmons R, Yang J, Bresson SM, Lisio M, Parise G, Conrad NK, Kalsotra A. Poly(A) tail length regulates PABPC1 expression to tune translation in the heart. Elife. 6. PMID 28653618 DOI: 10.7554/Elife.24139  0.795
2017 Lewis CJ, Pan T, Kalsotra A. RNA modifications and structures cooperate to guide RNA-protein interactions. Nature Reviews. Molecular Cell Biology. PMID 28144031 DOI: 10.1038/Nrm.2016.163  0.388
2017 Arif W, Datar G, Kalsotra A. Intersections of Post-Transcriptional Gene Regulatory Mechanisms with Intermediary Metabolism. Biochimica Et Biophysica Acta. PMID 28088440 DOI: 10.1016/J.Bbagrm.2017.01.004  0.796
2017 Chorghade S, Seimetz J, Emmons R, Yang J, Bresson SM, Lisio MD, Parise G, Conrad NK, Kalsotra A. Author response: Poly(A) tail length regulates PABPC1 expression to tune translation in the heart Elife. DOI: 10.7554/Elife.24139.022  0.777
2016 Bangru S, Kalsotra A. Advances in analyzing RNA diversity in eukaryotic transcriptomes: peering through the Omics lens. F1000research. 5: 2668. PMID 27909578 DOI: 10.12688/F1000Research.9511.1  0.746
2015 Bhate A, Parker DJ, Bebee TW, Ahn J, Arif W, Rashan EH, Chorghade S, Chau A, Lee JH, Anakk S, Carstens RP, Xiao X, Kalsotra A. ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation. Nature Communications. 6: 8768. PMID 26531099 DOI: 10.1038/Ncomms9768  0.818
2015 Jaiswal M, Haelterman NA, Sandoval H, Xiong B, Donti T, Kalsotra A, Yamamoto S, Cooper TA, Graham BH, Bellen HJ. Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress. Plos Biology. 13: e1002197. PMID 26176594 DOI: 10.1371/Journal.Pbio.1002197  0.543
2015 Li W, You B, Hoque M, Zheng D, Luo W, Ji Z, Park JY, Gunderson SI, Kalsotra A, Manley JL, Tian B. Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation. Plos Genetics. 11: e1005166. PMID 25906188 DOI: 10.1371/Journal.Pgen.1005166  0.382
2015 Chaturvedi P, Neelamraju Y, Arif W, Kalsotra A, Janga SC. Uncovering RNA binding proteins associated with age and gender during liver maturation. Scientific Reports. 5: 9512. PMID 25824884 DOI: 10.1038/Srep09512  0.799
2015 Chau A, Kalsotra A. Developmental insights into the pathology of and therapeutic strategies for DM1: Back to the basics. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 244: 377-90. PMID 25504326 DOI: 10.1002/Dvdy.24240  0.436
2014 Singh RK, Xia Z, Bland CS, Kalsotra A, Scavuzzo MA, Curk T, Ule J, Li W, Cooper TA. Rbfox2-coordinated alternative splicing of Mef2d and Rock2 controls myoblast fusion during myogenesis. Molecular Cell. 55: 592-603. PMID 25087874 DOI: 10.1016/J.Molcel.2014.06.035  0.643
2014 Giudice J, Xia Z, Wang ET, Scavuzzo MA, Ward AJ, Kalsotra A, Wang W, Wehrens XH, Burge CB, Li W, Cooper TA. Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development. Nature Communications. 5: 3603. PMID 24752171 DOI: 10.1038/Ncomms4603  0.644
2014 Kalsotra A, Singh RK, Gurha P, Ward AJ, Creighton CJ, Cooper TA. The Mef2 transcription network is disrupted in myotonic dystrophy heart tissue, dramatically altering miRNA and mRNA expression. Cell Reports. 6: 336-45. PMID 24412363 DOI: 10.1016/J.Celrep.2013.12.025  0.559
2011 Kalsotra A, Cooper TA. Functional consequences of developmentally regulated alternative splicing. Nature Reviews. Genetics. 12: 715-29. PMID 21921927 DOI: 10.1038/Nrg3052  0.641
2010 Kalsotra A, Wang K, Li PF, Cooper TA. MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development. Genes & Development. 24: 653-8. PMID 20299448 DOI: 10.1101/Gad.1894310  0.599
2008 Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, Burge CB, Cooper TA. A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart Proceedings of the National Academy of Sciences of the United States of America. 105: 20333-20338. PMID 19075228 DOI: 10.1073/Pnas.0809045105  0.599
2008 Castle JC, Zhang C, Shah JK, Kulkarni AV, Kalsotra A, Cooper TA, Johnson JM. Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines. Nature Genetics. 40: 1416-25. PMID 18978788 DOI: 10.1038/Ng.264  0.632
2008 Wang Y, Zhao J, Kalsotra A, Turman CM, Grill RJ, Dash PK, Strobel HW. CYP4Fs expression in rat brain correlates with changes in LTB4 levels after traumatic brain injury. Journal of Neurotrauma. 25: 1187-94. PMID 18847377 DOI: 10.1089/Neu.2008.0542  0.773
2008 Kalsotra A, Du L, Wang Y, Ladd PA, Kikuta Y, Duvic M, Boyd AS, Keeney DS, Strobel HW. Inflammation resolved by retinoid X receptor-mediated inactivation of leukotriene signaling pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 538-47. PMID 17884973 DOI: 10.1096/Fj.07-9244Com  0.613
2007 Kalsotra A, Anakk S, Brommer CL, Kikuta Y, Morgan ET, Strobel HW. Catalytic characterization and cytokine mediated regulation of cytochrome P450 4Fs in rat hepatocytes. Archives of Biochemistry and Biophysics. 461: 104-12. PMID 17418803 DOI: 10.1016/J.Abb.2007.02.027  0.744
2007 Kalsotra A, Zhao J, Anakk S, Dash PK, Strobel HW. Brain trauma leads to enhanced lung inflammation and injury: evidence for role of P4504Fs in resolution. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 963-74. PMID 16985506 DOI: 10.1038/Sj.Jcbfm.9600396  0.734
2006 Kalsotra A, Strobel HW. Cytochrome P450 4F subfamily: at the crossroads of eicosanoid and drug metabolism. Pharmacology & Therapeutics. 112: 589-611. PMID 16926051 DOI: 10.1016/J.Pharmthera.2006.03.008  0.605
2005 Kalsotra A, Cui X, Anakk S, Hinojos CA, Doris PA, Strobel HW. Renal localization, expression, and developmental regulation of P450 4F cytochromes in three substrains of spontaneously hypertensive rats. Biochemical and Biophysical Research Communications. 338: 423-31. PMID 16182239 DOI: 10.1016/J.Bbrc.2005.08.101  0.776
2004 Kalsotra A, Turman CM, Kikuta Y, Strobel HW. Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids. Toxicology and Applied Pharmacology. 199: 295-304. PMID 15364545 DOI: 10.1016/J.Taap.2003.12.033  0.772
2004 Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11. The Pharmacogenomics Journal. 4: 91-101. PMID 14770174 DOI: 10.1038/Sj.Tpj.6500222  0.773
2003 Kalsotra A, Turman CM, Dash PK, Strobel HW. Differential effects of traumatic brain injury on the cytochrome p450 system: a perspective into hepatic and renal drug metabolism. Journal of Neurotrauma. 20: 1339-50. PMID 14748982 DOI: 10.1089/089771503322686139  0.788
2003 Kalsotra A, Cui X, Antonovic L, Robida AM, Morgan ET, Strobel HW. Inflammatory prompts produce isoform-specific changes in the expression of leukotriene B(4) omega-hydroxylases in rat liver and kidney. Febs Letters. 555: 236-42. PMID 14644421 DOI: 10.1016/S0014-5793(03)01240-7  0.791
2003 Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJA, Strobel HW. Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1736-1738. PMID 12958193 DOI: 10.1096/Fj.02-1004Fje  0.763
2003 Cui X, Kalsotra A, Robida AM, Matzilevich D, Moore AN, Boehme CL, Morgan ET, Dash PK, Strobel HW. Expression of cytochromes P450 4F4 and 4F5 in infection and injury models of inflammation. Biochimica Et Biophysica Acta. 1619: 325-31. PMID 12573492 DOI: 10.1016/S0304-4165(02)00491-9  0.676
2002 Kalsotra A, Anakk S, Boehme CL, Strobel HW. Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 1022-8. PMID 12167568 DOI: 10.1124/Dmd.30.9.1022  0.758
Show low-probability matches.