Year |
Citation |
Score |
2013 |
Tantravedi S, Chakraborty S, Shah NH, Fishbein JC, Hosmane RS. Analogs of iso-azepinomycin as potential transition-state analog inhibitors of guanase: synthesis, biochemical screening, and structure-activity correlations of various selectively substituted imidazo[4,5-e][1,4]diazepines. Bioorganic & Medicinal Chemistry. 21: 4893-903. PMID 23891230 DOI: 10.1016/J.Bmc.2013.06.069 |
0.717 |
|
2013 |
Koissi N, Fishbein JC. Trapping of a cross-link formed by a major purine adduct of a metabolite of the carcinogen N-nitrosomorpholine by inorganic and biological reductants. Chemical Research in Toxicology. 26: 732-40. PMID 23587048 DOI: 10.1021/Tx3005289 |
0.464 |
|
2012 |
Chakraborty S, Shah NH, Fishbein JC, Hosmane RS. Investigations into specificity of azepinomycin for inhibition of guanase: discrimination between the natural heterocyclic inhibitor and its synthetic nucleoside analogues. Bioorganic & Medicinal Chemistry Letters. 22: 7214-8. PMID 23084905 DOI: 10.1016/J.Bmcl.2012.09.053 |
0.652 |
|
2012 |
Koissi N, Shah NH, Ginevan B, Eck WS, Roebuck BD, Fishbein JC. Lactone metabolite common to the carcinogens dioxane, diethylene glycol, and N-nitrosomorpholine: aqueous chemistry and failure to mediate liver carcinogenesis in the F344 rat. Chemical Research in Toxicology. 25: 1022-8. PMID 22458541 DOI: 10.1021/Tx3000076 |
0.551 |
|
2011 |
Chakraborty S, Shah NH, Fishbein JC, Hosmane RS. A novel transition state analog inhibitor of guanase based on azepinomycin ring structure: Synthesis and biochemical assessment of enzyme inhibition. Bioorganic & Medicinal Chemistry Letters. 21: 756-9. PMID 21183343 DOI: 10.1016/J.Bmcl.2010.11.109 |
0.634 |
|
2011 |
Pence MG, Blans P, Zink CN, Fishbein JC, Perrino FW. Bypass of N²-ethylguanine by human DNA polymerase κ. Dna Repair. 10: 56-64. PMID 20952260 DOI: 10.1016/J.Dnarep.2010.09.007 |
0.735 |
|
2010 |
Holland R, Fishbein JC. Chemistry of the cysteine sensors in Kelch-like ECH-associated protein 1. Antioxidants & Redox Signaling. 13: 1749-61. PMID 20486763 DOI: 10.1089/Ars.2010.3273 |
0.568 |
|
2010 |
Zink CN, Soissons N, Fishbein JC. Products of the direct reaction of the diazonium ion of a metabolite of the carcinogen N-nitrosomorpholine with purines of nucleosides and DNA. Chemical Research in Toxicology. 23: 1223-33. PMID 20443589 DOI: 10.1021/Tx100093A |
0.747 |
|
2009 |
Holland R, Navamal M, Velayutham M, Zweier JL, Kensler TW, Fishbein JC. Hydrogen peroxide is a second messenger in phase 2 enzyme induction by cancer chemopreventive dithiolethiones. Chemical Research in Toxicology. 22: 1427-34. PMID 19785463 DOI: 10.1021/Tx900110N |
0.596 |
|
2009 |
Pence MG, Blans P, Zink CN, Hollis T, Fishbein JC, Perrino FW. Lesion bypass of N2-ethylguanine by human DNA polymerase iota. The Journal of Biological Chemistry. 284: 1732-40. PMID 18984581 DOI: 10.1074/Jbc.M807296200 |
0.737 |
|
2008 |
Holland R, Hawkins AE, Eggler AL, Mesecar AD, Fabris D, Fishbein JC. Prospective type 1 and type 2 disulfides of Keap1 protein. Chemical Research in Toxicology. 21: 2051-60. PMID 18729328 DOI: 10.1021/Tx800226M |
0.581 |
|
2006 |
Upton DC, Wang X, Blans P, Perrino FW, Fishbein JC, Akman SA. Replication of N2-ethyldeoxyguanosine DNA adducts in the human embryonic kidney cell line 293. Chemical Research in Toxicology. 19: 960-7. PMID 16841965 DOI: 10.1021/Tx060084A |
0.512 |
|
2006 |
Upton DC, Wang X, Blans P, Perrino FW, Fishbein JC, Akman SA. Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli. Mutation Research. 599: 1-10. PMID 16488449 DOI: 10.1016/J.Mrfmmm.2005.12.014 |
0.481 |
|
2006 |
Zink CN, Kim HJ, Fishbein JC. Synthesis and aqueous chemistry of alpha-acetoxy-N-nitrosomorpholine: reactive intermediates and products. The Journal of Organic Chemistry. 71: 202-9. PMID 16388636 DOI: 10.1021/Jo051936Z |
0.722 |
|
2005 |
Lu X, Heilman JM, Blans P, Fishbein JC. The structure of DNA dictates purine atom site selectivity in alkylation by primary diazonium ions. Chemical Research in Toxicology. 18: 1462-70. PMID 16167839 DOI: 10.1021/Tx0501334 |
0.693 |
|
2005 |
Perrino FW, Harvey S, Blans P, Gelhaus S, Lacourse WR, Fishbein JC. Polymerization past the N2-isopropylguanine and the N6-isopropyladenine DNA lesions with the translesion synthesis DNA polymerases eta and iota and the replicative DNA polymerase alpha. Chemical Research in Toxicology. 18: 1451-61. PMID 16167838 DOI: 10.1021/Tx050114U |
0.525 |
|
2005 |
Velayutham M, Villamena FA, Navamal M, Fishbein JC, Zweier JL. Glutathione-mediated formation of oxygen free radicals by the major metabolite of oltipraz. Chemical Research in Toxicology. 18: 970-5. PMID 15962931 DOI: 10.1021/Tx049687H |
0.358 |
|
2004 |
Blans P, Fishbein JC. Determinants of selectivity in alkylation of nucleosides and DNA by secondary diazonium ions: evidence for, and consequences of, a preassociation mechanism. Chemical Research in Toxicology. 17: 1531-9. PMID 15540951 DOI: 10.1021/Tx0498004 |
0.527 |
|
2004 |
Agnew TE, Kim H, Fishbein JC. Diazonium ion chemistry: replacement of H by alkyl at the central carbon accelerates anSN2 substitution reaction Journal of Physical Organic Chemistry. 17: 483-488. DOI: 10.1002/Poc.768 |
0.354 |
|
2003 |
Perrino FW, Blans P, Harvey S, Gelhaus SL, McGrath C, Akman SA, Jenkins GS, LaCourse WR, Fishbein JC. The N2-ethylguanine and the O6-ethyl- and O6-methylguanine lesions in DNA: contrasting responses from the "bypass" DNA polymerase eta and the replicative DNA polymerase alpha. Chemical Research in Toxicology. 16: 1616-23. PMID 14680376 DOI: 10.1021/Tx034164F |
0.508 |
|
2003 |
Kim HJ, Fishbein JC. Reexamination of the aqueous chemistry of N-Nitroso-3-hydroxymorpholine, a metabolite of the carcinogen N-nitrosomorpholine. Chemical Research in Toxicology. 16: 715-20. PMID 12807354 DOI: 10.1021/Tx020114J |
0.487 |
|
2002 |
Navamal M, McGrath C, Stewart J, Blans P, Villamena F, Zweier J, Fishbein JC. Thiolytic chemistry of alternative precursors to the major metabolite of the cancer chemopreventive oltipraz. The Journal of Organic Chemistry. 67: 9406-13. PMID 12492345 DOI: 10.1021/Jo020588N |
0.381 |
|
2001 |
Carey KA, Kensler TW, Fishbein JC. Kinetic constraints for the thiolysis of 4-methyl-5-(pyrazin-2-yl)-1,2-dithiole-3-thione (oltipraz) and related dithiole-3-thiones in aqueous solution Chemical Research in Toxicology. 14: 939-945. PMID 11511166 DOI: 10.1021/Tx0100340 |
0.339 |
|
2000 |
Mesic M, Peuralahti J, Blans P, Fishbein JC. Mechanisms of decomposition of α-hydroxydialkylnitrosamines in aqueous solution Chemical Research in Toxicology. 13: 983-992. PMID 11080047 DOI: 10.1021/Tx000084P |
0.307 |
|
2000 |
Blans P, Fishbein JC. Predicted exocyclic amino group alkylation of 2'-deoxyadenosine and 2'- deoxyguanosine by the isopropyl cation Chemical Research in Toxicology. 13: 431-435. PMID 10858315 DOI: 10.1021/Tx000059J |
0.475 |
|
1999 |
Chahoua L, Vigroux A, Chiang Y, Fishbein JC. Formation and nucleophilic capture of N-nitrosiminium ions Canadian Journal of Chemistry. 77: 1148-1161. DOI: 10.1139/V99-108 |
0.473 |
|
1999 |
Chahoua L, Cai H, Fishbein JC. Cyclic α-acetoxynitrosamines: Mechanisms of decomposition and stability of α-hydroxynitrosamine and nitrosiminium ion reactive intermediates Journal of the American Chemical Society. 121: 5161-5169. DOI: 10.1021/Ja9902975 |
0.385 |
|
1999 |
Cai H, Fishbein JC. α-(acyloxy)dialkylnitrosamines: Effects of structure on the formation of N-nitrosiminium ions and a predicted change in mechanism Journal of the American Chemical Society. 121: 1826-1833. DOI: 10.1021/Ja9833218 |
0.381 |
|
1997 |
Chahoua L, Mesic M, Revis CL, Vigroux A, Fishbein JC. Evidence for the Formation of alpha-Hydroxydialkylnitrosamines in the pH-Independent Solvolysis of alpha-(Acyloxy)dialkylnitrosamines. The Journal of Organic Chemistry. 62: 2500-2504. PMID 11671589 DOI: 10.1021/Jo962003T |
0.336 |
|
1997 |
Cai H, Fishbein JC. Secondary α-deuterium kinetic isotope effects in the decomposition of simple α-acetoxydialkylnitrosamines: Nitrosiminium ion intermediates Tetrahedron. 53: 10671-10676. DOI: 10.1016/S0040-4020(97)00687-X |
0.326 |
|
1996 |
Chahoua L, Mesić M, Fishbein JC. Failure to isolate the first N-nitrosiminium cation Journal of Organic Chemistry. 61: 1512. DOI: 10.1021/Jo951545S |
0.323 |
|
1996 |
Finneman JI, Fishbein JC. Mechanisms of decomposition of (Z)-2,2,2-trifluoro-1-arylethanediazoates in aqueous media Journal of the American Chemical Society. 118: 7134-7138. DOI: 10.1021/Ja9614629 |
0.409 |
|
1995 |
Rajamäki M, Vigroux A, Chahoua L, Fishbein JC. N-nitrosiminium ions are ambident electrophiles Journal of Organic Chemistry. 60: 2324-2325. DOI: 10.1021/Jo00113A007 |
0.393 |
|
1995 |
Vigroux A, Kresge AJ, Fishbein JC. Generation and direct measurement of the reactivity of an N-nitrosiminium cation with nucleophiles in aqueous media Journal of the American Chemical Society. 117: 4433-4434. DOI: 10.1021/Ja00120A040 |
0.418 |
|
1995 |
Revis CL, Rajamäki M, Fishbein JC. Reexamination of the mechanisms of decomposition of simple α-acetoxynitrosamines in the physiological pH range Journal of Organic Chemistry. 60: 7733-7738. |
0.359 |
|
1995 |
Fishbein JC, McClelland RA. Cyclohexadienes from the rearrangement of O-aroyl-N-acetyl-N-(2,6- dimethylphenyl)hydroxylamines. Reaction in aqueous solution to meta- and para-substituted 2,6-dimethylacetanilides Journal of the Chemical Society, Perkin Transactions 2. 653-662. |
0.392 |
|
1992 |
Wichems DN, Nag S, Mills J, Fishbein JC. Evidence for intermediates and a change in rate-limiting step in the aminolysis of the carcinogen N-methyl-N′-nitro-N-nitrosoguanidine by cyclic amines Journal of the American Chemical Society. 114: 8846-8851. |
0.332 |
|
1992 |
Santala T, Fishbein JC. Thiolytic decomposition of the carcinogen N-methyl-N′-nitro-N-nitrosoguanidine. A change in rate-limiting step with nucleophile basicity controls alkylating activity Journal of the American Chemical Society. 114: 8852-8857. |
0.363 |
|
1992 |
Galtress CL, Morrow PR, Nag S, Smalley TL, Tschantz MF, Vaughn JS, Wichems DN, Ziglar SK, Fishbein JC. Mechanism for the solvolytic decomposition of the carcinogen N-methyl-n′-nitro-N-nitrosoguanidine in aqueous solutions Journal of the American Chemical Society. 114: 1406-1411. |
0.377 |
|
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