Year |
Citation |
Score |
2021 |
Schaupp CM, Botta D, White CC, Scoville DK, Srinouanprachanh S, Bammler TK, MacDonald J, Kavanagh TJ. Persistence of improved glucose homeostasis in Gclm null mice with age and cadmium treatment. Redox Biology. 49: 102213. PMID 34953454 DOI: 10.1016/j.redox.2021.102213 |
0.307 |
|
2020 |
Nicholas TP, Haick AK, Workman TW, Griffith WC, Nolin JD, Kavanagh TJ, Faustman EM, Altemeier WA. The effects of genotype × phenotype interactions on silver nanoparticle toxicity in organotypic cultures of murine tracheal epithelial cells. Nanotoxicology. 1-21. PMID 32574512 DOI: 10.1080/17435390.2020.1777475 |
0.344 |
|
2020 |
Fan X, Sell DR, Hao C, Liu S, Wang B, Wesson DW, Siedlak S, Zhu X, Kavanagh TJ, Harrison FE, Monnier VM. Vitamin C is a source of oxoaldehyde and glycative stress in age-related cataract and neurodegenerative diseases. Aging Cell. PMID 32567221 DOI: 10.1111/Acel.13176 |
0.34 |
|
2020 |
Breysse DH, Boone RM, Long CM, Merrill ME, Schaupp CM, White CC, Kavanagh TJ, Schmidt EE, Merrill GF. Carbonyl reductase 1 plays a significant role in converting doxorubicin to cardiotoxic doxorubicinol in mouse liver, but the majority of the doxorubicinol-forming activity remains unidentified. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31955137 DOI: 10.1124/Dmd.119.089326 |
0.373 |
|
2019 |
Mills MG, Ramsden R, Ma EY, Corrales J, Kristofco LA, Steele WB, Saari GN, Melnikov F, Kostal J, Kavanagh TJ, Zimmerman JB, Voutchkova-Kostal AM, Brooks BW, Coish P, Anastas PT, et al. CRISPR-generated Nrf2a loss- and gain-of-function mutants facilitate mechanistic analysis of chemical oxidative stress-mediated toxicity in zebrafish. Chemical Research in Toxicology. PMID 31858786 DOI: 10.1021/Acs.Chemrestox.9B00346 |
0.388 |
|
2019 |
Steele WB, Kristofco LA, Corrales J, Saari GN, Corcoran EJ, Hill BN, Mills MG, Gallagher E, Kavanagh TJ, Melnikov F, Zimmerman JB, Voutchkova-Kostal AM, Anastas PT, Kostal J, Brooks BW. Towards less hazardous industrial compounds: coupling quantum mechanical computations, biomarker responses and behavioral profiles identify bioactivity of SN2 electrophiles in alternative vertebrate models. Chemical Research in Toxicology. PMID 31789507 DOI: 10.1021/Acs.Chemrestox.9B00290 |
0.336 |
|
2019 |
Nicholas TP, Haick AK, Bammler TK, Workman TW, Kavanagh TJ, Faustman EM, Gharib SA, Altemeier WA. The Effects of Genotype × Phenotype Interactions on Transcriptional Response to Silver Nanoparticle Toxicity in Organotypic Cultures of Murine Tracheal Epithelial Cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31562762 DOI: 10.1093/Toxsci/Kfz209 |
0.33 |
|
2019 |
Martin ME, Reaves DK, Jeffcoat B, Enders JR, Costantini LM, Yeyeodu ST, Botta D, Kavanagh TJ, Fleming JM. Silver nanoparticles alter epithelial basement membrane integrity, cell adhesion molecule expression, and TGF-β1 secretion. Nanomedicine : Nanotechnology, Biology, and Medicine. 102070. PMID 31351238 DOI: 10.1016/J.Nano.2019.102070 |
0.303 |
|
2019 |
Scoville DK, Nolin JD, Ogden HL, An D, Afsharinejad Z, Johnson BW, Bammler TK, Gao X, Frevert CW, Altemeier WA, Hallstrand TS, Kavanagh TJ. Quantum dots and mouse strain influence house dust mite-induced allergic airway disease. Toxicology and Applied Pharmacology. PMID 30682383 DOI: 10.1016/J.Taap.2019.01.018 |
0.367 |
|
2018 |
Campbell MD, Duan J, Samuelson AT, Gaffrey MJ, Wang L, Bammler TK, Moore RJ, White CC, Kavanagh TJ, Voss JG, Szeto HH, Rabinovitch PS, Qian WJ, Marcinek DJ. Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radical Biology & Medicine. PMID 30597195 DOI: 10.1016/J.Freeradbiomed.2018.12.031 |
0.322 |
|
2018 |
Melnikov F, Botta D, White CC, Schmuck SC, Winfough M, Schaupp CM, Gallagher E, Brooks BW, Williams ES, Coish P, Anastas PT, Voutchkova A, Kostal J, Kavanagh TJ. Kinetics of Glutathione Depletion and Antioxidant Gene Expression as Indicators of Chemical Modes of Action Assessed in vitro in Mouse Hepatocytes with Enhanced Glutathione Synthesis. Chemical Research in Toxicology. PMID 30547568 DOI: 10.1021/Acs.Chemrestox.8B00259 |
0.443 |
|
2018 |
Weldon BA, Griffith WC, Workman T, Scoville DK, Kavanagh TJ, Faustman EM. In vitro to in vivo benchmark dose comparisons to inform risk assessment of quantum dot nanomaterials. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. PMID 29350469 DOI: 10.1002/Wnan.1507 |
0.302 |
|
2017 |
Wei Z, Caty J, Whitson J, Zhang AD, Srinivasagan R, Kavanagh TJ, Yan H, Fan X. Reduced glutathione level promotes epithelial-mesenchymal transition in lens epithelial cells via a Wnt/β-catenin-mediated pathway: relevance for cataract therapy. The American Journal of Pathology. PMID 28827139 DOI: 10.1016/J.Ajpath.2017.07.018 |
0.368 |
|
2017 |
Scoville DK, Botta D, Galdanes K, Schmuck SC, White CC, Stapleton PL, Bammler TK, MacDonald JW, Altemeier WA, Hernandez M, Kleeberger SR, Chen LC, Gordon T, Kavanagh TJ. Genetic determinants of susceptibility to silver nanoparticle-induced acute lung inflammation in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28716969 DOI: 10.1096/Fj.201700187R |
0.328 |
|
2017 |
Vandivort TC, Birkland TP, Domiciano TP, Mitra S, Kavanagh TJ, Parks WC. Stromelysin-2 (MMP-10) facilitates clearance and moderates inflammation and cell death following lung exposure to long multiwalled carbon nanotubes. International Journal of Nanomedicine. 12: 1019-1031. PMID 28223796 DOI: 10.2147/Ijn.S123484 |
0.303 |
|
2017 |
Schaupp C, White C, Botta D, Scoville D, Merrill G, Kavanagh T. Plasticity of Antioxidant Defense Pathways in Response to Aging and Cadmium in Glutathione-Deficient Mice Free Radical Biology and Medicine. 112: 53. DOI: 10.1016/J.Freeradbiomed.2017.10.071 |
0.42 |
|
2016 |
Mischley LK, Conley KE, Shankland EG, Kavanagh TJ, Rosenfeld ME, Duda JE, White CC, Wilbur TK, De La Torre PU, Padowski JM. Central nervous system uptake of intranasal glutathione in Parkinson's disease. Npj Parkinson's Disease. 2: 16002. PMID 28725693 DOI: 10.1038/Npjparkd.2016.2 |
0.316 |
|
2016 |
Corrales J, Kristofco LA, Steele WB, Saari GN, Kostal J, Williams ES, Mills M, Gallagher EP, Kavanagh TJ, Simcox N, Shen LQ, Melnikov F, Zimmerman JB, Voutchkova-Kostal AM, Anastas PT, et al. Towards the design of less hazardous chemicals: Exploring comparative oxidative stress in two common animal models. Chemical Research in Toxicology. PMID 27750016 DOI: 10.1021/Acs.Chemrestox.6B00246 |
0.356 |
|
2016 |
Cartwright MM, Schmuck SC, Corredor C, Wang B, Scoville DK, Chisholm CR, Wilkerson HW, Afsharinejad Z, Bammler TK, Posner JD, Shutthanandan V, Baer DR, Mitra S, Altemeier WA, Kavanagh TJ. The pulmonary inflammatory response to multiwalled carbon nanotubes is influenced by gender and glutathione synthesis. Redox Biology. 9: 264-275. PMID 27596734 DOI: 10.1016/J.Redox.2016.08.009 |
0.409 |
|
2016 |
Kyriakides M, Maitre L, Stamper BD, Mohar I, Kavanagh TJ, Foster J, Wilson ID, Holmes E, Nelson SD, Coen M. Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer. Archives of Toxicology. PMID 26746206 DOI: 10.1007/S00204-015-1655-X |
0.744 |
|
2016 |
Schaupp CM, White CC, Botta D, Scoville DK, Kavanagh TJ. Age and Cadmium as Modifiers of Metabolic and Thiol-Based Redox Homeostasis in Glutathione-Deficient Mice Free Radical Biology and Medicine. 100. DOI: 10.1016/J.Freeradbiomed.2016.10.221 |
0.425 |
|
2015 |
Fox JR, Cox DP, Drury BE, Gould TR, Kavanagh TJ, Paulsen MH, Sheppard L, Simpson CD, Stewart JA, Larson TV, Kaufman JD. Chemical characterization and in vitro toxicity of diesel exhaust particulate matter generated under varying conditions. Air Quality, Atmosphere, & Health. 8: 507-519. PMID 26539254 DOI: 10.1007/S11869-014-0301-8 |
0.325 |
|
2015 |
Neal A, Rountree AM, Philips CW, Kavanagh TJ, Williams DP, Newham P, Khalil G, Cook DL, Sweet IR. Quantification of Low-Level Drug Effects Using Real-Time, in vitro Measurement of Oxygen Consumption Rate. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26396153 DOI: 10.1093/Toxsci/Kfv208 |
0.318 |
|
2015 |
Lim J, Nakamura BN, Mohar I, Kavanagh TJ, Luderer U. Glutamate cysteine ligase modifier subunit (Gclm) null mice have increased ovarian oxidative stress and accelerated age-related ovarian failure. Endocrinology. en20151206. PMID 26083875 DOI: 10.1210/En.2015-1206 |
0.781 |
|
2015 |
Stamper BD, Garcia ML, Nguyen DQ, Beyer RP, Bammler TK, Farin FM, Kavanagh TJ, Nelson SD. p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo. Gene Regulation and Systems Biology. 9: 1-14. PMID 26056430 DOI: 10.4137/Grsb.S25388 |
0.355 |
|
2015 |
Ye F, White CC, Jin Y, Hu X, Hayden S, Zhang X, Gao X, Kavanagh TJ, Chiu DT. Toxicity and oxidative stress induced by semiconducting polymer dots in RAW264.7 mouse macrophages. Nanoscale. 7: 10085-93. PMID 25978523 DOI: 10.1039/C5Nr01857A |
0.385 |
|
2015 |
Costa LG, Pellacani C, Dao K, Kavanagh TJ, Roque PJ. The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice. Neurotoxicology. 48: 68-76. PMID 25797475 DOI: 10.1016/J.Neuro.2015.03.008 |
0.443 |
|
2015 |
Ren X, Gaile DP, Gong Z, Qiu W, Ge Y, Zhang C, Huang C, Yan H, Olson JR, Kavanagh TJ, Wu H. Arsenic responsive microRNAs in vivo and their potential involvement in arsenic-induced oxidative stress. Toxicology and Applied Pharmacology. 283: 198-209. PMID 25625412 DOI: 10.1016/J.Taap.2015.01.014 |
0.539 |
|
2015 |
Harris IS, Treloar AE, Inoue S, Sasaki M, Gorrini C, Lee KC, Yung KY, Brenner D, Knobbe-Thomsen CB, Cox MA, Elia A, Berger T, Cescon DW, Adeoye A, Brüstle A, ... ... Kavanagh TJ, et al. Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression. Cancer Cell. 27: 211-22. PMID 25620030 DOI: 10.1016/J.Ccell.2014.11.019 |
0.301 |
|
2015 |
Schaupp CM, White CC, Merrill GF, Kavanagh TJ. Metabolism of doxorubicin to the cardiotoxic metabolite doxorubicinol is increased in a mouse model of chronic glutathione deficiency: A potential role for carbonyl reductase 3. Chemico-Biological Interactions. 234: 154-61. PMID 25446851 DOI: 10.1016/J.Cbi.2014.11.010 |
0.442 |
|
2015 |
Lee V, McMahan RS, Hu X, Gao X, Faustman EM, Griffith WC, Kavanagh TJ, Eaton DL, McGuire JK, Parks WC. Amphiphilic polymer-coated CdSe/ZnS quantum dots induce pro-inflammatory cytokine expression in mouse lung epithelial cells and macrophages. Nanotoxicology. 9: 336-43. PMID 24983898 DOI: 10.3109/17435390.2014.930532 |
0.375 |
|
2014 |
Mohar I, Stamper BD, Rademacher PM, White CC, Nelson SD, Kavanagh TJ. Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6. Redox Biology. 2: 377-87. PMID 24563856 DOI: 10.1016/J.Redox.2014.01.008 |
0.768 |
|
2013 |
Riehle KJ, Haque J, McMahan RS, Kavanagh TJ, Fausto N, Campbell JS. Sustained Glutathione Deficiency Interferes with the Liver Response to TNF-α and Liver Regeneration after Partial Hepatectomy in Mice. Journal of Liver: Disease & Transplantation. 1. PMID 24611135 |
0.302 |
|
2013 |
Weldy CS, Luttrell IP, White CC, Morgan-Stevenson V, Cox DP, Carosino CM, Larson TV, Stewart JA, Kaufman JD, Kim F, Chitaley K, Kavanagh TJ. Glutathione (GSH) and the GSH synthesis gene Gclm modulate plasma redox and vascular responses to acute diesel exhaust inhalation in mice. Inhalation Toxicology. 25: 444-54. PMID 23808636 DOI: 10.3109/08958378.2013.801004 |
0.765 |
|
2013 |
Föller M, Harris IS, Elia A, John R, Lang F, Kavanagh TJ, Mak TW. Functional significance of glutamate-cysteine ligase modifier for erythrocyte survival in vitro and in vivo. Cell Death and Differentiation. 20: 1350-8. PMID 23787995 DOI: 10.1038/Cdd.2013.70 |
0.457 |
|
2013 |
McConnachie LA, Botta D, White CC, Weldy CS, Wilkerson HW, Yu J, Dills R, Yu X, Griffith WC, Faustman EM, Farin FM, Gill SE, Parks WC, Hu X, Gao X, ... ... Kavanagh TJ, et al. The Glutathione Synthesis Gene Gclm Modulates Amphiphilic Polymer-Coated CdSe/ZnS Quantum Dot-Induced Lung Inflammation in Mice Plos One. 8. PMID 23724032 DOI: 10.1371/Journal.Pone.0064165 |
0.764 |
|
2013 |
Liang LP, Kavanagh TJ, Patel M. Glutathione deficiency in Gclm null mice results in complex I inhibition and dopamine depletion following paraquat administration. Toxicological Sciences : An Official Journal of the Society of Toxicology. 134: 366-73. PMID 23704229 DOI: 10.1093/Toxsci/Kft112 |
0.361 |
|
2013 |
Bir SC, Shen X, Kavanagh TJ, Kevil CG, Pattillo CB. Control of angiogenesis dictated by picomolar superoxide levels. Free Radical Biology & Medicine. 63: 135-42. PMID 23685287 DOI: 10.1016/J.Freeradbiomed.2013.05.015 |
0.406 |
|
2013 |
Giordano G, Tait L, Furlong CE, Cole TB, Kavanagh TJ, Costa LG. Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression. Free Radical Biology & Medicine. 58: 98-108. PMID 23376469 DOI: 10.1016/J.Freeradbiomed.2013.01.019 |
0.343 |
|
2013 |
Giordano G, Kavanagh TJ, Faustman EM, White CC, Costa LG. Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 399-408. PMID 23315585 DOI: 10.1093/Toxsci/Kft002 |
0.462 |
|
2013 |
Lim J, Lawson GW, Nakamura BN, Ortiz L, Hur JA, Kavanagh TJ, Luderer U. Glutathione-deficient mice have increased sensitivity to transplacental benzo[a]pyrene-induced premature ovarian failure and ovarian tumorigenesis. Cancer Research. 73: 908-17. PMID 23135907 DOI: 10.1158/0008-5472.Can-12-3636 |
0.344 |
|
2013 |
McConnachie LA, White CC, Botta D, Zadworny ME, Cox DP, Beyer RP, Hu X, Eaton DL, Gao X, Kavanagh TJ. Heme oxygenase expression as a biomarker of exposure to amphiphilic polymer-coated CdSe/ZnS quantum dots. Nanotoxicology. 7: 181-91. PMID 22264017 DOI: 10.3109/17435390.2011.648224 |
0.327 |
|
2012 |
Smith WE, Brownell J, White CC, Afsharinejad Z, Tsai J, Hu X, Polyak SJ, Gao X, Kavanagh TJ, Eaton DL. In vitro toxicity assessment of amphiphillic polymer-coated CdSe/ZnS quantum dots in two human liver cell models. Acs Nano. 6: 9475-84. PMID 23039050 DOI: 10.1021/Nn302288R |
0.326 |
|
2012 |
Weldy CS, Luttrell IP, White CC, Morgan-Stevenson V, Bammler TK, Beyer RP, Afsharinejad Z, Kim F, Chitaley K, Kavanagh TJ. Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice. Free Radical Biology & Medicine. 53: 1264-78. PMID 22824862 DOI: 10.1016/J.Freeradbiomed.2012.07.006 |
0.768 |
|
2012 |
Bai N, Tranfield EM, Kavanagh TJ, Kaufman JD, Rosenfeld ME, van Eeden SF. Exposure to diesel exhaust upregulates COX-2 expression in ApoE knockout mice. Inhalation Toxicology. 24: 518-27. PMID 22746401 DOI: 10.3109/08958378.2012.696221 |
0.391 |
|
2012 |
Liu RM, Vayalil PK, Ballinger C, Dickinson DA, Huang WT, Wang S, Kavanagh TJ, Matthews QL, Postlethwait EM. Transforming growth factor β suppresses glutamate-cysteine ligase gene expression and induces oxidative stress in a lung fibrosis model. Free Radical Biology & Medicine. 53: 554-63. PMID 22634145 DOI: 10.1016/J.Freeradbiomed.2012.05.016 |
0.321 |
|
2012 |
Takakusa H, Mohar I, Kavanagh TJ, Kelly EJ, Kaspera R, Nelson SD. Protein tyrosine nitration of mitochondrial carbamoyl phosphate synthetase 1 and its functional consequences. Biochemical and Biophysical Research Communications. 420: 54-60. PMID 22402285 DOI: 10.1016/J.Bbrc.2012.02.114 |
0.759 |
|
2012 |
Nakamura BN, Mohar I, Lawson GW, Cortés MM, Hoang YD, Ortiz L, Patel R, Rau BA, McConnachie LA, Kavanagh TJ, Luderer U. Increased sensitivity to testicular toxicity of transplacental benzo[a]pyrene exposure in male glutamate cysteine ligase modifier subunit knockout (Gclm-/-) mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 126: 227-41. PMID 22253057 DOI: 10.1093/Toxsci/Kfs017 |
0.759 |
|
2012 |
Kavanagh TJ. Compensatory gene expression in gluthathione deficient mice: implications for ageing and disease susceptibility Free Radical Biology and Medicine. 53. DOI: 10.1016/J.Freeradbiomed.2012.08.143 |
0.333 |
|
2011 |
Weldy CS, White CC, Wilkerson HW, Larson TV, Stewart JA, Gill SE, Parks WC, Kavanagh TJ. Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice. Inhalation Toxicology. 23: 724-35. PMID 21967497 DOI: 10.3109/08958378.2011.608095 |
0.751 |
|
2011 |
Weldy CS, Wilkerson HW, Larson TV, Stewart JA, Kavanagh TJ. DIESEL particulate exposed macrophages alter endothelial cell expression of eNOS, iNOS, MCP1, and glutathione synthesis genes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 25: 2064-73. PMID 21920430 DOI: 10.1016/J.Tiv.2011.08.008 |
0.748 |
|
2011 |
Callegari A, Liu Y, White CC, Chait A, Gough P, Raines EW, Cox D, Kavanagh TJ, Rosenfeld ME. Gain and loss of function for glutathione synthesis: impact on advanced atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2473-82. PMID 21868708 DOI: 10.1161/Atvbaha.111.229765 |
0.396 |
|
2011 |
Kisby GE, Fry RC, Lasarev MR, Bammler TK, Beyer RP, Churchwell M, Doerge DR, Meira LB, Palmer VS, Ramos-Crawford AL, Ren X, Sullivan RC, Kavanagh TJ, Samson LD, Zarbl H, et al. The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner. Plos One. 6: e20911. PMID 21731631 DOI: 10.1371/Journal.Pone.0020911 |
0.542 |
|
2011 |
Bai N, Kido T, Kavanagh TJ, Kaufman JD, Rosenfeld ME, van Breemen C, van Eeden SF. Exposure to diesel exhaust up-regulates iNOS expression in ApoE knockout mice. Toxicology and Applied Pharmacology. 255: 184-92. PMID 21722660 DOI: 10.1016/J.Taap.2011.06.013 |
0.361 |
|
2011 |
Cole TB, Giordano G, Co AL, Mohar I, Kavanagh TJ, Costa LG. Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative Stress. Journal of Toxicology. 2011: 157687. PMID 21559092 DOI: 10.1155/2011/157687 |
0.777 |
|
2011 |
Nakamura BN, Fielder TJ, Hoang YD, Lim J, McConnachie LA, Kavanagh TJ, Luderer U. Lack of maternal glutamate cysteine ligase modifier subunit (Gclm) decreases oocyte glutathione concentrations and disrupts preimplantation development in mice. Endocrinology. 152: 2806-15. PMID 21558310 DOI: 10.1210/En.2011-0207 |
0.357 |
|
2011 |
Stamper BD, Mohar I, Kavanagh TJ, Nelson SD. Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting. Chemical Research in Toxicology. 24: 549-58. PMID 21329376 DOI: 10.1021/Tx1004198 |
0.756 |
|
2011 |
Nakamura BN, Fielder TJ, Hoang YD, Lim J, McConnachie LA, Kavanagh TJ, Luderer U. Premature Ovarian Failure and Abnormal Preimplantation Development in Female Mice Deficient in Glutathione Synthesis. Biology of Reproduction. 85: 71-71. DOI: 10.1093/Biolreprod/85.S1.71 |
0.313 |
|
2011 |
Scoville DK, White CC, Botta D, McConnachie L, Zadworny M, Hu X, Gao X, Kavanagh TJ. Mouse Strain-Dependent Susceptibility To Quantum Dot Induced Lung Inflammation and Oxidative Stress Free Radical Biology and Medicine. 51: S115. DOI: 10.1016/J.Freeradbiomed.2011.10.361 |
0.31 |
|
2011 |
Marcinek DJ, Siegel MP, Knowels G, Kruse S, Kavanagh TJ, Syrjala KL. Reduced in Vivo Coupling of Oxidative Phosphorylation is an Early Marker of Oxidant-Induced Mitochondrial Toxicity Free Radical Biology and Medicine. 51: S136. DOI: 10.1016/J.Freeradbiomed.2011.10.286 |
0.352 |
|
2011 |
Weldy CS, Luttrell IP, White CC, Larson TV, Stewart JA, Chitaley K, Kavanagh TJ. Glutathione (GSH) and the GSH Synthesis Gene GCLM Modulate Vascular Reactivity and Diesel Exhaust-Induced Perturbations in Mice Free Radical Biology and Medicine. 51: S165. DOI: 10.1016/J.Freeradbiomed.2011.10.236 |
0.755 |
|
2010 |
Dabrowski MJ, Zolnerciks JK, Balogh LM, Greene RJ, Kavanagh TJ, Atkins WM. Stereoselective effects of 4-hydroxynonenal in cultured mouse hepatocytes. Chemical Research in Toxicology. 23: 1601-7. PMID 20873854 DOI: 10.1021/Tx100190K |
0.33 |
|
2010 |
Pattillo CB, Pardue S, Shen X, Fang K, Langston W, Jourd'heuil D, Kavanagh TJ, Patel RP, Kevil CG. ICAM-1 cytoplasmic tail regulates endothelial glutathione synthesis through a NOX4/PI3-kinase-dependent pathway. Free Radical Biology & Medicine. 49: 1119-28. PMID 20633529 DOI: 10.1016/J.Freeradbiomed.2010.06.030 |
0.345 |
|
2010 |
Haque JA, McMahan RS, Campbell JS, Shimizu-Albergine M, Wilson AM, Botta D, Bammler TK, Beyer RP, Montine TJ, Yeh MM, Kavanagh TJ, Fausto N. Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 90: 1704-17. PMID 20548286 DOI: 10.1038/Labinvest.2010.112 |
0.434 |
|
2010 |
Krejsa CM, Franklin CC, White CC, Ledbetter JA, Schieven GL, Kavanagh TJ. Rapid activation of glutamate cysteine ligase following oxidative stress. The Journal of Biological Chemistry. 285: 16116-24. PMID 20332089 DOI: 10.1074/Jbc.M110.116210 |
0.736 |
|
2010 |
Shao J, Dabrowski MJ, White CC, Kavanagh TJ, Gallagher EP. Flow cytometric analysis of BDE 47 mediated injury to rainbow trout gill epithelial cells. Aquatic Toxicology (Amsterdam, Netherlands). 97: 42-50. PMID 20053465 DOI: 10.1016/J.Aquatox.2009.11.013 |
0.38 |
|
2010 |
Weldy CS, Luttrell I, Morgan V, Cox D, Larson T, Stewart J, Kim F, Chitaley K, Kavanagh T. Acetylcholine-Stimulated Aortic Dilation is Impaired by Diesel Particulate Exposed Macrophages; Investigation of Susceptibility in Mice with Compromised Glutathione Synthesis Free Radical Biology and Medicine. 49: S31. DOI: 10.1016/J.Freeradbiomed.2010.10.057 |
0.735 |
|
2010 |
Cox DP, Drury BE, Kavanagh TJ. A Comparative Analysis of Diesel Exhaust Particulates with Varying Physicochemical Properties on Viability and Stress Response in Murine Endothelial Cells Free Radical Biology and Medicine. 49. DOI: 10.1016/J.Freeradbiomed.2010.10.017 |
0.307 |
|
2009 |
Mohar I, Botta D, White CC, McConnachie LA, Kavanagh TJ. Glutamate cysteine ligase (GCL) transgenic and gene-targeted mice for controlling glutathione synthesis. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit6.16. PMID 23045016 DOI: 10.1002/0471140856.Tx0616S39 |
0.794 |
|
2009 |
Thompson JA, White CC, Cox DP, Chan JY, Kavanagh TJ, Fausto N, Franklin CC. Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes. Free Radical Biology & Medicine. 46: 1614-25. PMID 19328227 DOI: 10.1016/J.Freeradbiomed.2009.03.016 |
0.471 |
|
2009 |
Giordano G, Li L, White CC, Farin FM, Wilkerson HW, Kavanagh TJ, Costa LG. Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells. Journal of Neurochemistry. 109: 525-38. PMID 19200344 DOI: 10.1111/J.1471-4159.2009.05969.X |
0.442 |
|
2009 |
Giordano G, Kavanagh TJ, Costa LG. Mouse cerebellar astrocytes protect cerebellar granule neurons against toxicity of the polybrominated diphenyl ether (PBDE) mixture DE-71. Neurotoxicology. 30: 326-9. PMID 19150461 DOI: 10.1016/J.Neuro.2008.12.009 |
0.364 |
|
2009 |
Franklin CC, Backos DS, Mohar I, White CC, Forman HJ, Kavanagh TJ. Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase. Molecular Aspects of Medicine. 30: 86-98. PMID 18812186 DOI: 10.1016/J.Mam.2008.08.009 |
0.774 |
|
2009 |
Bea F, Hudson FN, Neff-Laford H, White CC, Kavanagh TJ, Kreuzer J, Preusch MR, Blessing E, Katus HA, Rosenfeld ME. Homocysteine stimulates antioxidant response element-mediated expression of glutamate-cysteine ligase in mouse macrophages. Atherosclerosis. 203: 105-11. PMID 18691715 DOI: 10.1016/J.Atherosclerosis.2008.06.024 |
0.815 |
|
2009 |
Wu H, White CC, Isanhart JP, McBride TJ, Kavanagh TJ, Hooper MJ. Optimization and application of glutamate cysteine ligase measurement in wildlife species. Ecotoxicology and Environmental Safety. 72: 572-8. PMID 18403016 DOI: 10.1016/J.Ecoenv.2008.03.001 |
0.361 |
|
2008 |
Giordano G, Kavanagh TJ, Costa LG. Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels. Toxicology and Applied Pharmacology. 232: 161-8. PMID 18656495 DOI: 10.1016/J.Taap.2008.06.018 |
0.423 |
|
2008 |
Botta D, White CC, Vliet-Gregg P, Mohar I, Shi S, McGrath MB, McConnachie LA, Kavanagh TJ. Modulating GSH synthesis using glutamate cysteine ligase transgenic and gene-targeted mice. Drug Metabolism Reviews. 40: 465-77. PMID 18642143 DOI: 10.1080/03602530802186587 |
0.821 |
|
2008 |
Garry MR, Kavanagh TJ, Faustman EM, Sidhu JS, Liao R, Ware C, Vliet PA, Deeb SS. Sensitivity of mouse lung fibroblasts heterozygous for GPx4 to oxidative stress. Free Radical Biology & Medicine. 44: 1075-87. PMID 18206984 DOI: 10.1016/J.Freeradbiomed.2007.12.002 |
0.428 |
|
2008 |
Shao J, White CC, Dabrowski MJ, Kavanagh TJ, Eckert ML, Gallagher EP. The role of mitochondrial and oxidative injury in BDE 47 toxicity to human fetal liver hematopoietic stem cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 101: 81-90. PMID 17916640 DOI: 10.1093/Toxsci/Kfm256 |
0.375 |
|
2007 |
Giordano G, White CC, Mohar I, Kavanagh TJ, Costa LG. Glutathione levels modulate domoic acid induced apoptosis in mouse cerebellar granule cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 100: 433-44. PMID 17804861 DOI: 10.1093/Toxsci/Kfm236 |
0.772 |
|
2007 |
Shi S, Hudson FN, Botta D, McGrath MB, White CC, Neff-LaFord HD, Dabrowski MJ, Singh NP, Kavanagh TJ. Over expression of glutamate cysteine ligase increases cellular resistance to H2O2-induced DNA single-strand breaks. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 71: 686-92. PMID 17623891 DOI: 10.1002/Cyto.A.20434 |
0.798 |
|
2007 |
McConnachie LA, Mohar I, Hudson FN, Ware CB, Ladiges WC, Fernandez C, Chatterton-Kirchmeier S, White CC, Pierce RH, Kavanagh TJ. Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 628-36. PMID 17584759 DOI: 10.1093/Toxsci/Kfm165 |
0.79 |
|
2007 |
Beyer RP, Fry RC, Lasarev MR, McConnachie LA, Meira LB, Palmer VS, Powell CL, Ross PK, Bammler TK, Bradford BU, Cranson AB, Cunningham ML, Fannin RD, Higgins GM, Hurban P, ... ... Kavanagh TJ, et al. Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 326-37. PMID 17562736 DOI: 10.1093/Toxsci/Kfm150 |
0.307 |
|
2007 |
Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A. Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 115: 221-8. PMID 17479437 DOI: 10.1055/S-2007-970574 |
0.584 |
|
2007 |
Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicology and Applied Pharmacology. 219: 181-9. PMID 17084875 DOI: 10.1016/J.Taap.2006.09.016 |
0.431 |
|
2006 |
Giordano G, White CC, McConnachie LA, Fernandez C, Kavanagh TJ, Costa LG. Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency. Molecular Pharmacology. 70: 2116-26. PMID 17000861 DOI: 10.1124/Mol.106.027748 |
0.308 |
|
2006 |
Botta D, Shi S, White CC, Dabrowski MJ, Keener CL, Srinouanprachanh SL, Farin FM, Ware CB, Ladiges WC, Pierce RH, Fausto N, Kavanagh TJ. Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice. The Journal of Biological Chemistry. 281: 28865-75. PMID 16840778 DOI: 10.1074/Jbc.M605143200 |
0.629 |
|
2006 |
Bekris LM, Viernes HM, Farin FM, Maier LA, Kavanagh TJ, Takaro TK. Chronic beryllium disease and glutathione biosynthesis genes. Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine. 48: 599-606. PMID 16766924 DOI: 10.1097/01.Jom.0000201845.02369.Ba |
0.637 |
|
2006 |
Bekris LM, Kavanagh TJ, Lernmark A. Targeting type 1 diabetes before and at the clinical onset of disease. Endocrine, Metabolic & Immune Disorders Drug Targets. 6: 103-24. PMID 16611168 DOI: 10.2174/187153006776056576 |
0.585 |
|
2006 |
Dabrowski MJ, Maeda D, Zebala J, Lu WD, Mahajan S, Kavanagh TJ, Atkins WM. Glutathione S-transferase P1-1 expression modulates sensitivity of human kidney 293 cells to photodynamic therapy with hypericin. Archives of Biochemistry and Biophysics. 449: 94-103. PMID 16546115 DOI: 10.1016/J.Abb.2006.02.009 |
0.389 |
|
2005 |
Bekris LM, Shephard C, Peterson M, Hoehna J, Van Yserloo B, Rutledge E, Farin F, Kavanagh TJ, Lernmark A. Glutathione-s-transferase M1 and T1 polymorphisms and associations with type 1 diabetes age-at-onset. Autoimmunity. 38: 567-75. PMID 16390810 DOI: 10.1080/08916930500407238 |
0.628 |
|
2005 |
Ho HK, White CC, Fernandez C, Fausto N, Kavanagh TJ, Nelson SD, Bruschi SA. Nrf2 activation involves an oxidative-stress independent pathway in tetrafluoroethylcysteine-induced cytotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 86: 354-64. PMID 15901913 DOI: 10.1093/Toxsci/Kfi205 |
0.434 |
|
2004 |
Díaz D, Krejsa CM, White CC, Charleston JS, Kavanagh TJ. Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development. Reproductive Toxicology (Elmsford, N.Y.). 19: 117-29. PMID 15336720 DOI: 10.1016/J.Reprotox.2004.06.006 |
0.802 |
|
2004 |
Botta D, Franklin CC, White CC, Krejsa CM, Dabrowski MJ, Pierce RH, Fausto N, Kavanagh TJ. Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis. Free Radical Biology & Medicine. 37: 632-42. PMID 15288121 DOI: 10.1016/J.Freeradbiomed.2004.05.027 |
0.73 |
|
2004 |
Kevil CG, Pruitt H, Kavanagh TJ, Wilkerson J, Farin F, Moellering D, Darley-Usmar VM, Bullard DC, Patel RP. Regulation of endothelial glutathione by ICAM-1: implications for inflammation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1321-3. PMID 15180961 DOI: 10.1096/Fj.03-1401Fje |
0.395 |
|
2004 |
Krzywanski DM, Dickinson DA, Iles KE, Wigley AF, Franklin CC, Liu RM, Kavanagh TJ, Forman HJ. Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress. Archives of Biochemistry and Biophysics. 423: 116-25. PMID 14871475 DOI: 10.1016/J.Abb.2003.11.004 |
0.447 |
|
2003 |
Franklin CC, Rosenfeld-Franklin ME, White C, Kavanagh TJ, Fausto N. TGFbeta1-induced suppression of glutathione antioxidant defenses in hepatocytes: caspase-dependent post-translational and caspase-independent transcriptional regulatory mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1535-7. PMID 12824300 DOI: 10.1096/Fj.02-0867Fje |
0.416 |
|
2003 |
White CC, Viernes H, Krejsa CM, Botta D, Kavanagh TJ. Fluorescence-based microtiter plate assay for glutamate-cysteine ligase activity. Analytical Biochemistry. 318: 175-80. PMID 12814619 DOI: 10.1016/S0003-2697(03)00143-X |
0.708 |
|
2003 |
Luderer U, Diaz D, Faustman EM, Kavanagh TJ. Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis. Molecular Reproduction and Development. 65: 254-61. PMID 12784246 DOI: 10.1002/Mrd.10298 |
0.671 |
|
2003 |
Bea F, Hudson FN, Chait A, Kavanagh TJ, Rosenfeld ME. Induction of glutathione synthesis in macrophages by oxidized low-density lipoproteins is mediated by consensus antioxidant response elements. Circulation Research. 92: 386-93. PMID 12600891 DOI: 10.1161/01.Res.0000059561.65545.16 |
0.812 |
|
2002 |
Faustman EM, Ponce RA, Ou YC, Mendoza MA, Lewandowski T, Kavanagh T. Investigations of methylmercury-induced alterations in neurogenesis. Environmental Health Perspectives. 110: 859-64. PMID 12426147 DOI: 10.1289/Ehp.02110S5859 |
0.367 |
|
2002 |
Franklin CC, Krejsa CM, Pierce RH, White CC, Fausto N, Kavanagh TJ. Caspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell Death. The American Journal of Pathology. 160: 1887-94. PMID 12000740 DOI: 10.1016/S0002-9440(10)61135-2 |
0.708 |
|
2002 |
Díaz D, Krejsa CM, Kavanagh TJ. Expression of glutamate-cysteine ligase during mouse development. Molecular Reproduction and Development. 62: 83-91. PMID 11933164 DOI: 10.1002/Mrd.10076 |
0.799 |
|
2001 |
White CC, Krejsa CJ, Eaton DL, Kavanagh TJ. HPLC-based assays for enzymes of glutathione biosynthesis. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit6.5. PMID 23045057 DOI: 10.1002/0471140856.Tx0605S00 |
0.332 |
|
2001 |
Luderer U, Kavanagh TJ, White CC, Faustman EM. Gonadotropin regulation of glutathione synthesis in the rat ovary. Reproductive Toxicology (Elmsford, N.Y.). 15: 495-504. PMID 11780957 DOI: 10.1016/S0890-6238(01)00157-5 |
0.363 |
|
2001 |
Díaz D, Krejsa CM, Kavanagh TJ. Localization of glutamate-cysteine ligase mRNA and protein in mouse kidney and induction with methylmercury. Toxicology Letters. 123: 33-41. PMID 11514103 DOI: 10.1016/S0378-4274(01)00377-0 |
0.738 |
|
2001 |
Díaz D, Krejsa CM, White CC, Keener CL, Farin FM, Kavanagh TJ. Tissue specific changes in the expression of glutamate-cysteine ligase mRNAs in mice exposed to methylmercury. Toxicology Letters. 122: 119-29. PMID 11439218 DOI: 10.1016/S0378-4274(01)00341-1 |
0.744 |
|
2000 |
Thompson SA, White CC, Krejsa CM, Eaton DL, Kavanagh TJ. Modulation of glutathione and glutamate-L-cysteine ligase by methylmercury during mouse development. Toxicological Sciences : An Official Journal of the Society of Toxicology. 57: 141-6. PMID 10966520 DOI: 10.1093/Toxsci/57.1.141 |
0.743 |
|
2000 |
Hudson FN, Kavanagh TJ. Cloning and characterization of the proximal promoter region of the mouse glutamate-L-cysteine ligase regulatory subunit gene. Biochimica Et Biophysica Acta. 1492: 447-51. PMID 10899580 DOI: 10.1016/S0167-4781(00)00128-7 |
0.775 |
|
2000 |
Pierce RH, Campbell JS, Stephenson AB, Franklin CC, Chaisson M, Poot M, Kavanagh TJ, Rabinovitch PS, Fausto N. Disruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell line. The American Journal of Pathology. 157: 221-36. PMID 10880392 DOI: 10.1016/S0002-9440(10)64533-6 |
0.379 |
|
2000 |
Järvinen K, Pietarinen-Runtti P, Linnainmaa K, Raivio KO, Krejsa CM, Kavanagh T, Kinnula VL. Antioxidant defense mechanisms of human mesothelioma and lung adenocarcinoma cells American Journal of Physiology - Lung Cellular and Molecular Physiology. 278. PMID 10749746 DOI: 10.1152/Ajplung.2000.278.4.L696 |
0.709 |
|
1999 |
Kirlin WG, Cai J, Thompson SA, Diaz D, Kavanagh TJ, Jones DP. Glutathione redox potential in response to differentiation and enzyme inducers. Free Radical Biology & Medicine. 27: 1208-18. PMID 10641713 DOI: 10.1016/S0891-5849(99)00145-8 |
0.685 |
|
1999 |
Siitonen T, Alaruikka P, Mäntymaa P, Savolainen ER, Kavanagh TJ, Krejsa CM, Franklin CC, Kinnula V, Koistinen P. Protection of acute myeloblastic leukemia cells against apoptotic cell death by high glutathione and gamma-glutamylcysteine synthetase levels during etoposide-induced oxidative stress. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 10: 1361-7. PMID 10631466 DOI: 10.1023/A:1008382912096 |
0.733 |
|
1999 |
Thompson SA, White CC, Krejsa CM, Diaz D, Woods JS, Eaton DL, Kavanagh TJ. Induction of glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) in the brains of adult female mice subchronically exposed to methylmercury. Toxicology Letters. 110: 1-9. PMID 10593589 DOI: 10.1016/S0378-4274(99)00133-2 |
0.803 |
|
1999 |
Ou YC, White CC, Krejsa CM, Ponce RA, Kavanagh TJ, Faustman EM. The role of intracellular glutathione in methylmercury-induced toxicity in embryonic neuronal cells. Neurotoxicology. 20: 793-804. PMID 10591515 |
0.723 |
|
1999 |
Woods JS, Kavanagh TJ, Corral J, Reese AW, Diaz D, Ellis ME. The role of glutathione in chronic adaptation to oxidative stress: studies in a normal rat kidney epithelial (NRK52E) cell model of sustained upregulation of glutathione biosynthesis. Toxicology and Applied Pharmacology. 160: 207-16. PMID 10544055 DOI: 10.1006/Taap.1999.8774 |
0.686 |
|
1999 |
Nelson KC, Carlson JL, Newman ML, Sternberg P, Jones DP, Kavanagh TJ, Diaz D, Cai J, Wu M. Effect of dietary inducer dimethylfumarate on glutathione in cultured human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 40: 1927-35. PMID 10440245 |
0.607 |
|
1999 |
Ou YC, Thompson SA, Ponce RA, Schroeder J, Kavanagh TJ, Faustman EM. Induction of the cell cycle regulatory gene p21 (Waf1, Cip1) following methylmercury exposure in vitro and in vivo. Toxicology and Applied Pharmacology. 157: 203-12. PMID 10373404 DOI: 10.1006/Taap.1999.8685 |
0.394 |
|
1997 |
Ou YC, Thompson SA, Kirchner SC, Kavanagh TJ, Faustman EM. Induction of growth arrest and DNA damage-inducible genes Gadd45 and Gadd153 in primary rodent embryonic cells following exposure to Methylmercury Toxicology and Applied Pharmacology. 147: 31-38. PMID 9356304 DOI: 10.1006/Taap.1997.8235 |
0.392 |
|
1997 |
Reid LL, Botta D, Shao J, Hudson FN, Kavanagh TJ. Molecular cloning and sequencing of the cDNA encoding mouse glutamate-cysteine ligase regulatory subunit. Biochimica Et Biophysica Acta. 1353: 107-10. PMID 9294003 DOI: 10.1016/S0167-4781(97)00092-4 |
0.762 |
|
1997 |
Reid LL, Botta D, Lu Y, Gallagher EP, Kavanagh TJ. Molecular cloning and sequencing of the cDNA encoding the catalytic subunit of mouse glutamate-cysteine ligase. Biochimica Et Biophysica Acta. 1352: 233-7. PMID 9224945 DOI: 10.1016/S0167-4781(97)00058-4 |
0.311 |
|
1997 |
Krejsa CM, Nadler SG, Esselstyn JM, Kavanagh TJ, Ledbetter JA, Schieven GL. Role of oxidative stress in the action of vanadium phosphotyrosine phosphatase inhibitors. Redox independent activation of NF-kappaB. The Journal of Biological Chemistry. 272: 11541-9. PMID 9111069 DOI: 10.1074/Jbc.272.17.11541 |
0.717 |
|
1996 |
Poot M, Hudson FN, Grossmann A, Rabinovitch PS, Kavanagh TJ. Probenicid inhibition of fluorescence extrusion after MCB-staining of rat-1 fibroblasts. Cytometry. 23: 78-81. PMID 14650445 DOI: 10.1002/(Sici)1097-0320(19960101)23:1<78::Aid-Cyto12>3.0.Co;2-T |
0.768 |
|
1996 |
Sopher BL, Fukuchi KI, Kavanagh TJ, Furlong CE, Martin GM. Neurodegenerative mechanisms in alzheimer disease - A role for oxidative damage in amyloid β protein precursor-mediated cell death Molecular and Chemical Neuropathology. 29: 153-168. PMID 8971693 DOI: 10.1007/Bf02814999 |
0.375 |
|
1996 |
Li S, Thompson SA, Kavanagh TJ, Woods JS. Localization by in situ hybridization of γ-glutamylcysteine synthetase mRNA expression in rat kidney following acute methylmercury treatment Toxicology and Applied Pharmacology. 141: 59-67. PMID 8917676 DOI: 10.1016/S0041-008X(96)80009-3 |
0.366 |
|
1996 |
Heinonen JT, Sidhu JS, Reilly MT, Farin FM, Omiecinski CJ, Eaton DL, Kavanagh TJ. Assessment of regional cytochrome P450 activities in rat liver slices using resorufin substrates and fluorescence confocal laser cytometry Environmental Health Perspectives. 104: 536-543. PMID 8743442 DOI: 10.1289/Ehp.96104536 |
0.316 |
|
1996 |
Krejsa CM, Nadler SG, Esselstyn JM, Kavanagh TJ, Ledbtter JA, Schieven GL. The differential role of oxidative stress in the inactivation of protein tyrosine kinases, map kinase, and nfκb by vanadium phosphotyrosine phosphatase inhibitors Faseb Journal. 10. |
0.692 |
|
1995 |
Poot M, Teubert H, Rabinovitch PS, Kavanagh TJ. De novo synthesis of glutathione is required for both entry into and progression through the cell cycle Journal of Cellular Physiology. 163: 555-560. PMID 7539813 DOI: 10.1002/Jcp.1041630316 |
0.325 |
|
1994 |
Ponce RA, Kavanagh TJ, Mottet NK, Whittaker SG, Faustman EM. Effects of methyl mercury on the cell cycle of primary rat CNS cells in vitro. Toxicology and Applied Pharmacology. 127: 83-90. PMID 8048057 DOI: 10.1006/Taap.1994.1142 |
0.31 |
|
1994 |
Kavanagh TJ, Raghu G, White CC, Martin GM, Rabinovitch PS, Eaton DL. Enhancement of glutathione content in glutathione synthetase-deficient fibroblasts from a patient with 5-oxoprolinuria via metabolic cooperation with normal fibroblasts. Experimental Cell Research. 212: 69-76. PMID 7909755 DOI: 10.1006/Excr.1994.1119 |
0.356 |
|
1993 |
Kavanagh TJ, Grossmann A, Jinneman JC, Kanner SB, White CC, Eaton DL, Ledbetter JA, Rabinovitch PS. The effect of 1-chloro-2,4-dinitrobenzene exposure on antigen receptor (CD3)-stimulated transmembrane signal transduction in purified subsets of human peripheral blood lymphocytes. Toxicology and Applied Pharmacology. 119: 91-9. PMID 8470127 DOI: 10.1006/Taap.1993.1047 |
0.309 |
|
1993 |
Sidhu JS, Kavanagh TJ, Reilly MT. Direct determination of functional activity of cytochrome p-4501 a1 and nadph dt-diaphorase in hepatoma cell lines using noninvasive scanning laser cytometry Journal of Toxicology and Environmental Health. 40: 177-194. PMID 7693959 DOI: 10.1080/15287399309531786 |
0.327 |
|
1992 |
Kanner SB, Kavanagh TJ, Grossmann A, Hu SL, Bolen JB, Rabinovitch PS, Ledbetter JA. Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase Cγ1 Proceedings of the National Academy of Sciences of the United States of America. 89: 300-304. PMID 1370350 DOI: 10.1073/Pnas.89.1.300 |
0.325 |
|
1990 |
Kavanagh TJ, Grossmann A, Jaecks EP, Jinneman JC, Eaton DL, Martin GM, Rabinovitch PS. Proliferative capacity of human peripheral blood lymphocytes sorted on the basis of glutathione content Journal of Cellular Physiology. 145: 472-480. PMID 1703168 DOI: 10.1002/Jcp.1041450312 |
0.311 |
|
1988 |
Kavanagh TJ, Martin GM, Livesey JC, Rabinovitch PS. Direct evidence of intercellular sharing of glutathione via metabolic cooperation Journal of Cellular Physiology. 137: 353-359. PMID 3192619 DOI: 10.1002/Jcp.1041370220 |
0.345 |
|
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