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William B. Guggino - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Cell Biology
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Year Citation  Score
2019 Yanda MK, Guggino WB, Cebotaru L. A new role for heat shock factor 27 in the pathophysiology of Clostridium difficile toxin B. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31709831 DOI: 10.1152/Ajpgi.00166.2019  0.336
2019 Bergbower EAS, Sabirzhanova I, Boinot C, Guggino WB, Cebotaru L. Restoration of F508-del Function by Transcomplementation: The Partners Meet in the Endoplasmic Reticulum. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 52: 1267-1279. PMID 31026390 DOI: 10.33594/000000089  0.321
2018 Sabirzhanova I, Boinot C, Guggino WB, Cebotaru L. Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 51: 1489-1499. PMID 30485852 DOI: 10.1159/000495596  0.368
2018 Yanda MK, Liu Q, Cebotaru V, Guggino WB, Cebotaru L. Role of calcium in adult onset polycystic kidney disease. Cellular Signalling. PMID 30296477 DOI: 10.1016/J.Cellsig.2018.10.003  0.374
2018 Liu Q, Sabirzhanova I, Yanda MK, Bergbower EAS, Boinot C, Guggino WB, Cebotaru L. Rescue of CFTR NBD2 mutants N1303K and S1235R is influenced by the functioning of the autophagosome. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 29936070 DOI: 10.1016/J.Jcf.2018.05.016  0.394
2018 Krishnan V, Park SA, Shin SS, Alon L, Tressler CM, Stokes W, Banerjee J, Sorrell ME, Tian Y, Fridman GY, Celnik P, Pevsner J, Guggino WB, Gilad AA, Pelled G. Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields. Scientific Reports. 8: 8764. PMID 29884813 DOI: 10.1038/S41598-018-27087-9  0.316
2018 Bergbower E, Boinot C, Sabirzhanova I, Guggino WB, Cebotaru L. The CFTR-Associated Ligand Arrests the Trafficking of the Mutant ΔF508 CFTR Channel in the ER Contributing to Cystic Fibrosis Cellular Physiology and Biochemistry. 45: 639-655. PMID 29402832 DOI: 10.1159/000487120  0.797
2017 Yanda MK, Liu Q, Cebotaru V, Guggino WB, Cebotaru L. Histone deacetylase 6 Inhibition reduces cysts by decreasing via cAMP and Ca2+ in knockout mouse models of polycystic kidney disease. The Journal of Biological Chemistry. PMID 28887310 DOI: 10.1074/Jbc.M117.803775  0.353
2016 Wang H, Cebotaru L, Lee HW, Yang Q, Pollard BS, Pollard HB, Guggino WB. CFTR Controls the Activity of NF-κB by Enhancing the Degradation of TRADD. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 40: 1063-1078. PMID 27960153 DOI: 10.1159/000453162  0.489
2016 Cebotaru L, Liu Q, Yanda M, Boinot C, Outeda P, Huso DL, Watnick T, Guggino WB, Cebotaru V. Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease. Kidney International. PMID 27165822 DOI: 10.1016/J.Kint.2016.01.026  0.342
2016 Lopes-Pacheco M, Sabirzhanova I, Rapino D, Morales MM, Guggino WB, Cebotaru L. Correctors rescue CFTR mutations in nucleotide-binding domain 1 (NBD1) by modulating proteostasis. Chembiochem : a European Journal of Chemical Biology. PMID 26864378 DOI: 10.1002/Cbic.201500620  0.395
2016 Veit G, Avramescu RG, Chiang AN, Houck SA, Cai Z, Peters KW, Hong JS, Pollard HB, Guggino WB, Balch WE, Skach WR, Cutting GR, Frizzell RA, Sheppard DN, Cyr DM, et al. From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations. Molecular Biology of the Cell. 27: 424-33. PMID 26823392 DOI: 10.1091/Mbc.E14-04-0935  0.366
2016 Cebotaru L, Boinot C, Sabirzhanova I, Guggino W. 10 Gene therapy to rescue of premature stop mutations R1162X and W1282X Journal of Cystic Fibrosis. 15: S54. DOI: 10.1016/S1569-1993(16)30250-8  0.303
2015 Lopes-Pacheco M, Boinot C, Sabirzhanova I, Morales MM, Guggino WB, Cebotaru L. Combination of correctors rescue ΔF508-CFTR by reducing its association with Hsp 40 and 27. The Journal of Biological Chemistry. PMID 26336106 DOI: 10.1074/Jbc.M115.671925  0.389
2015 Sabirzhanova I, Lopes Pacheco M, Rapino D, Grover R, Handa JT, Guggino WB, Cebotaru L. Rescuing Trafficking Mutants of the ATP-binding Cassette Protein, ABCA4, with Small Molecule Correctors as a Treatment for Stargardt Eye Disease. The Journal of Biological Chemistry. 290: 19743-55. PMID 26092729 DOI: 10.1074/Jbc.M115.647685  0.368
2015 Rapino D, Sabirzhanova I, Lopes-Pacheco M, Grover R, Guggino WB, Cebotaru L. Rescue of NBD2 mutants N1303K and S1235R of CFTR by small-molecule correctors and transcomplementation. Plos One. 10: e0119796. PMID 25799511 DOI: 10.1371/Journal.Pone.0119796  0.356
2014 Cebotaru L, Guggino WB. Complement yourself: Transcomplementation rescues partially folded mutant proteins. Biophysical Reviews. 6: 169-180. PMID 24949105 DOI: 10.1007/S12551-014-0137-3  0.463
2014 Schuster BS, Kim AJ, Kays JC, Kanzawa MM, Guggino WB, Boyle MP, Rowe SM, Muzyczka N, Suk JS, Hanes J. Overcoming the cystic fibrosis sputum barrier to leading adeno-associated virus gene therapy vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1484-93. PMID 24869933 DOI: 10.1038/Mt.2014.89  0.304
2014 Peruchetti DB, Cheng J, Caruso-Neves C, Guggino WB. Mis-regulation of mammalian target of rapamycin (mTOR) complexes induced by albuminuria in proximal tubules. The Journal of Biological Chemistry. 289: 16790-801. PMID 24790108 DOI: 10.1074/Jbc.M114.549717  0.313
2014 Cebotaru V, Cebotaru L, Kim H, Chiaravalli M, Boletta A, Qian F, Guggino WB. Polycystin-1 negatively regulates Polycystin-2 expression via the aggresome/autophagosome pathway. The Journal of Biological Chemistry. 289: 6404-14. PMID 24459142 DOI: 10.1074/Jbc.M113.501205  0.362
2014 Suk JS, Kim AJ, Trehan K, Schneider CS, Cebotaru L, Woodward OM, Boylan NJ, Boyle MP, Lai SK, Guggino WB, Hanes J. Lung gene therapy with highly compacted DNA nanoparticles that overcome the mucus barrier. Journal of Controlled Release : Official Journal of the Controlled Release Society. 178: 8-17. PMID 24440664 DOI: 10.1016/J.Jconrel.2014.01.007  0.653
2013 Cheng J, Guggino W. Ubiquitination and degradation of CFTR by the E3 ubiquitin ligase MARCH2 through its association with adaptor proteins CAL and STX6. Plos One. 8: e68001. PMID 23818989 DOI: 10.1371/Journal.Pone.0068001  0.372
2013 Lee HW, Cheng J, Kovbasnjuk O, Donowitz M, Guggino WB. Insulin-like growth factor 1 (IGF-1) enhances the protein expression of CFTR. Plos One. 8: e59992. PMID 23555857 DOI: 10.1371/Journal.Pone.0059992  0.575
2013 Woodward OM, Tukaye DN, Cui J, Greenwell P, Constantoulakis LM, Parker BS, Rao A, Köttgen M, Maloney PC, Guggino WB. Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules. Proceedings of the National Academy of Sciences of the United States of America. 110: 5223-8. PMID 23493553 DOI: 10.1073/Pnas.1214530110  0.77
2013 Cebotaru L, Woodward O, Cebotaru V, Guggino WB. Transcomplementation by a truncation mutant of cystic fibrosis transmembrane conductance regulator (CFTR) EnhancesδF508 processing through a biomolecular interaction Journal of Biological Chemistry. 288: 10505-10512. PMID 23463513 DOI: 10.1074/Jbc.M112.420489  0.719
2013 Tukaye DN, Kwon SH, Guggino WB. The GAP portion of Pseudomonas aeruginosa type III secreted toxin ExoS upregulates total and surface levels of wild type CFTR. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 31: 153-65. PMID 23428533 DOI: 10.1159/000343357  0.763
2013 Ramalingam S, London V, Kandavelou K, Cebotaru L, Guggino W, Civin C, Chandrasegaran S. Generation and genetic engineering of human induced pluripotent stem cells using designed zinc finger nucleases. Stem Cells and Development. 22: 595-610. PMID 22931452 DOI: 10.1089/Scd.2012.0245  0.312
2013 Woodward OM, Guggino WB. Anion Channels Seldin and Geibisch's the Kidney. 1: 1019-1045. DOI: 10.1016/B978-0-12-381462-3.00031-8  0.639
2012 Prota LF, Cebotaru L, Cheng J, Wright J, Vij N, Morales MM, Guggino WB. Dexamethasone regulates CFTR expression in Calu-3 cells with the involvement of chaperones HSP70 and HSP90. Plos One. 7: e47405. PMID 23272037 DOI: 10.1371/Journal.Pone.0047405  0.401
2012 Ramsey BW, Banks-Schlegel S, Accurso FJ, Boucher RC, Cutting GR, Engelhardt JF, Guggino WB, Karp CL, Knowles MR, Kolls JK, LiPuma JJ, Lynch S, McCray PB, Rubenstein RC, Singh PK, et al. Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report. American Journal of Respiratory and Critical Care Medicine. 185: 887-92. PMID 22312017 DOI: 10.1164/Rccm.201111-2068Ws  0.311
2012 Cebotaru L, Woodward O, Guggino W. WS15.5 Transcomplementation by a truncation mutant of CFTR, Δ27-264 CFTR, rescues both trafficking and chloride channel function of ΔF508 CFTR Journal of Cystic Fibrosis. 11: S34. DOI: 10.1016/S1569-1993(12)60107-6  0.421
2011 Peruchetti DB, Pinheiro AA, Landgraf SS, Wengert M, Takiya CM, Guggino WB, Caruso-Neves C. (Na+ + K+)-ATPase is a target for phosphoinositide 3-kinase/protein kinase B and protein kinase C pathways triggered by albumin. The Journal of Biological Chemistry. 286: 45041-7. PMID 22057272 DOI: 10.1074/Jbc.M111.260737  0.339
2011 Liang L, Woodward OM, Chen Z, Cotter R, Guggino WB. A novel role of protein tyrosine kinase2 in mediating chloride secretion in human airway epithelial cells. Plos One. 6: e21991. PMID 21765932 DOI: 10.1371/Journal.Pone.0021991  0.714
2011 Santoso NG, Cebotaru L, Guggino WB. Polycystin-1, 2, and STIM1 interact with IP(3)R to modulate ER Ca release through the PI3K/Akt pathway. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 27: 715-26. PMID 21691089 DOI: 10.1159/000330080  0.72
2011 Bomberger JM, Guggino WB, Stanton BA. Methods to monitor cell surface expression and endocytic trafficking of CFTR in polarized epithelial cells. Methods in Molecular Biology (Clifton, N.J.). 741: 271-83. PMID 21594791 DOI: 10.1007/978-1-61779-117-8_18  0.414
2011 Peters KW, Okiyoneda T, Balch WE, Braakman I, Brodsky JL, Guggino WB, Penland CM, Pollard HB, Sorscher EJ, Skach WR, Thomas PJ, Lukacs GL, Frizzell RA. CFTR Folding Consortium: methods available for studies of CFTR folding and correction. Methods in Molecular Biology (Clifton, N.J.). 742: 335-53. PMID 21547742 DOI: 10.1007/978-1-61779-120-8_20  0.379
2011 Al-Shanti N, Faulkner SH, Saini A, Loram I, Stewart CE, Zhang Z, Li X, Liu G, Gao L, Guo C, Kong T, Wang H, Gao R, Wang Z, Zhu X, ... ... Guggino WB, et al. Contents Vol. 27, 2011 Cellular Physiology and Biochemistry. 27. DOI: 10.1159/000330089  0.674
2010 Lassance-Soares RM, Cheng J, Krasnov K, Cebotaru L, Cutting GR, Souza-Menezes J, Morales MM, Guggino WB. The hypertonic environment differentially regulates wild-type CFTR and TNR-CFTR chloride channels. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 26: 577-86. PMID 21063095 DOI: 10.1159/000322325  0.424
2010 Woodward OM, Li Y, Yu S, Greenwell P, Wodarczyk C, Boletta A, Guggino WB, Qian F. Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1. Plos One. 5: e12305. PMID 20808796 DOI: 10.1371/Journal.Pone.0012305  0.695
2010 Kwon Y, Kim SH, Ronderos DS, Lee Y, Akitake B, Woodward OM, Guggino WB, Smith DP, Montell C. Drosophila TRPA1 channel is required to avoid the naturally occurring insect repellent citronellal. Current Biology : Cb. 20: 1672-8. PMID 20797863 DOI: 10.1016/J.Cub.2010.08.016  0.689
2010 Gena P, Calamita G, Guggino WB. Cadmium impairs albumin reabsorption by down-regulating megalin and ClC5 channels in renal proximal tubule cells. Environmental Health Perspectives. 118: 1551-6. PMID 20576581 DOI: 10.1289/Ehp.0901874  0.303
2010 Kim SH, Lee Y, Akitake B, Woodward OM, Guggino WB, Montell C. Drosophila TRPA1 channel mediates chemical avoidance in gustatory receptor neurons. Proceedings of the National Academy of Sciences of the United States of America. 107: 8440-5. PMID 20404155 DOI: 10.1073/Pnas.1001425107  0.677
2010 Atwell S, Brouillette CG, Conners K, Emtage S, Gheyi T, Guggino WB, Hendle J, Hunt JF, Lewis HA, Lu F, Protasevich II, Rodgers LA, Romero R, Wasserman SR, Weber PC, et al. Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant. Protein Engineering, Design & Selection : Peds. 23: 375-84. PMID 20150177 DOI: 10.1093/Protein/Gzq004  0.355
2010 Cheng J, Cebotaru V, Cebotaru L, Guggino WB. Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator. Molecular Biology of the Cell. 21: 1178-87. PMID 20130090 DOI: 10.1091/Mbc.E09-03-0229  0.415
2010 Hoque KM, Woodward OM, van Rossum DB, Zachos NC, Chen L, Leung GP, Guggino WB, Guggino SE, Tse CM. Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion. The Journal of General Physiology. 135: 43-58. PMID 20038525 DOI: 10.1083/Jcb1877Oia18  0.704
2010 Lewis HA, Wang C, Zhao X, Hamuro Y, Conners K, Kearins MC, Lu F, Sauder JM, Molnar KS, Coales SJ, Maloney PC, Guggino WB, Wetmore DR, Weber PC, Hunt JF. Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry Journal of Molecular Biology. 396: 406-430. PMID 19944699 DOI: 10.1016/J.Jmb.2009.11.051  0.322
2010 Zhou B, Zhuang J, Gu D, Wang H, Cebotaru L, Guggino WB, Cai H. WNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathway. Journal of the American Society of Nephrology : Jasn. 21: 82-92. PMID 19875813 DOI: 10.1681/Asn.2008121275  0.361
2009 Li Y, Santoso NG, Yu S, Woodward OM, Qian F, Guggino WB. Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease. The Journal of Biological Chemistry. 284: 36431-41. PMID 19854836 DOI: 10.1074/Jbc.M109.068916  0.767
2009 Woodward OM, Köttgen A, Coresh J, Boerwinkle E, Guggino WB, Köttgen M. Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout. Proceedings of the National Academy of Sciences of the United States of America. 106: 10338-42. PMID 19506252 DOI: 10.1073/Pnas.0901249106  0.655
2009 Liang L, MacDonald K, Schwiebert EM, Zeitlin PL, Guggino WB. Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway. American Journal of Physiology. Cell Physiology. 296: C131-41. PMID 18987251 DOI: 10.1152/Ajpcell.00346.2008  0.414
2008 Krasnov KV, Tzetis M, Cheng J, Guggino WB, Cutting GR. Localization studies of rare missense mutations in cystic fibrosis transmembrane conductance regulator (CFTR) facilitate interpretation of genotype-phenotype relationships. Human Mutation. 29: 1364-72. PMID 18951463 DOI: 10.1002/Humu.20866  0.36
2008 Souza-Menezes J, Tukaye DN, Novaira HJ, Guggino WB, Morales MM. Small nuclear RNAs U11 and U12 modulate expression of TNR-CFTR mRNA in mammalian kidneys. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 22: 93-100. PMID 18769035 DOI: 10.1159/000149786  0.741
2008 Cebotaru L, Vij N, Ciobanu I, Wright J, Flotte T, Guggino WB. Cystic fibrosis transmembrane regulator missing the first four transmembrane segments increases wild type and DeltaF508 processing. The Journal of Biological Chemistry. 283: 21926-33. PMID 18508776 DOI: 10.1074/Jbc.M709156200  0.422
2008 Cebotaru L, Vij N, Ciobanu I, Wright J, Guggino W. CFTR missing the first four transmembrane segments enhances wild type and ΔF508 CFTR processing Journal of Cystic Fibrosis. 7: S16. DOI: 10.1016/S1569-1993(08)60060-0  0.303
2008 Wang Y, Guggino WB, Fong P. Anion Channels Seldin and Giebisch's the Kidney. 769-792. DOI: 10.1016/B978-012088488-9.50032-2  0.442
2007 Kwon SH, Pollard H, Guggino WB. Knockdown of NHERF1 enhances degradation of temperature rescued DeltaF508 CFTR from the cell surface of human airway cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 20: 763-72. PMID 17982258 DOI: 10.1159/000110436  0.697
2007 Souza-Menezes J, Morales MM, Tukaye DN, Guggino SE, Guggino WB. Absence of ClC5 in knockout mice leads to glycosuria, impaired renal glucose handling and low proximal tubule GLUT2 protein expression. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 20: 455-64. PMID 17762172 DOI: 10.1159/000107529  0.718
2007 Fischer AC, Smith CI, Cebotaru L, Zhang X, Askin FB, Wright J, Guggino SE, Adams RJ, Flotte T, Guggino WB. Expression of a truncated cystic fibrosis transmembrane conductance regulator with an AAV5-pseudotyped vector in primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 756-63. PMID 17299412 DOI: 10.1038/Sj.Mt.6300059  0.344
2007 Wolde M, Fellows A, Cheng J, Kivenson A, Coutermarsh B, Talebian L, Karlson K, Piserchio A, Mierke DF, Stanton BA, Guggino WB, Madden DR. Targeting CAL as a negative regulator of DeltaF508-CFTR cell-surface expression: an RNA interference and structure-based mutagenetic approach. The Journal of Biological Chemistry. 282: 8099-109. PMID 17158866 DOI: 10.1074/Jbc.M611049200  0.451
2006 Caruso-Neves C, Pinheiro AA, Cai H, Souza-Menezes J, Guggino WB. PKB and megalin determine the survival or death of renal proximal tubule cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 18810-5. PMID 17121993 DOI: 10.1073/Pnas.0605029103  0.331
2006 Ikeda M, Fong P, Cheng J, Boletta A, Qian F, Zhang XM, Cai H, Germino GG, Guggino WB. A regulatory role of polycystin-1 on cystic fibrosis transmembrane conductance regulator plasma membrane expression. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 18: 9-20. PMID 16914886 DOI: 10.1159/000095133  0.41
2006 Pollard HB, Eidelman O, Jozwik C, Huang W, Srivastava M, Ji XD, McGowan B, Norris CF, Todo T, Darling T, Mogayzel PJ, Zeitlin PL, Wright J, Guggino WB, Metcalf E, et al. De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells. Molecular & Cellular Proteomics : McP. 5: 1628-37. PMID 16829594 DOI: 10.1074/Mcp.M600091-Mcp200  0.36
2006 Guggino WB, Stanton BA. New insights into cystic fibrosis: molecular switches that regulate CFTR. Nature Reviews. Molecular Cell Biology. 7: 426-36. PMID 16723978 DOI: 10.1038/Nrm1949  0.398
2006 Cai H, Cebotaru V, Wang YH, Zhang XM, Cebotaru L, Guggino SE, Guggino WB. WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells. Kidney International. 69: 2162-70. PMID 16688122 DOI: 10.1038/Sj.Ki.5000333  0.545
2006 Novaira HJ, Ornellas DS, Ortiga-Carvalho TM, Zhang XM, Souza-Menezes J, Guggino SE, Guggino WB, Morales MM. Atrial natriuretic peptide modulates cystic fibrosis transmembrane conductance regulator chloride channel expression in rat proximal colon and human intestinal epithelial cells. The Journal of Endocrinology. 189: 155-65. PMID 16614390 DOI: 10.1677/Joe.1.06460  0.417
2006 Wright JM, Merlo CA, Reynolds JB, Zeitlin PL, Garcia JG, Guggino WB, Boyle MP. Respiratory epithelial gene expression in patients with mild and severe cystic fibrosis lung disease. American Journal of Respiratory Cell and Molecular Biology. 35: 327-36. PMID 16614352 DOI: 10.1165/Rcmb.2005-0359Oc  0.348
2006 van den Hove MF, Croizet-Berger K, Jouret F, Guggino SE, Guggino WB, Devuyst O, Courtoy PJ. The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland. Endocrinology. 147: 1287-96. PMID 16306076 DOI: 10.1210/En.2005-1149  0.353
2006 Beitz E, Liu K, Ikeda M, Guggino WB, Agre P, Yasui M. Determinants of AQP6 trafficking to intracellular sites versus the plasma membrane in transfected mammalian cells. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 98: 101-9. PMID 15892693 DOI: 10.1042/Bc20050025  0.305
2006 Cebotaru L, Flotté T, Guggino W. 56 AAV Δ264CFTR enhances wt CFTR expression and maturation of ΔF508CFTR Journal of Cystic Fibrosis. 5: S13. DOI: 10.1016/S1569-1993(06)80052-4  0.324
2006 Cebotaru L, Flotte TR, Guggino WB. 498. AAV Δ264CFTR Enhances Maturation of ΔF508CFTR and wt CFTR Expression Molecular Therapy. 13: S193. DOI: 10.1016/J.Ymthe.2006.08.568  0.344
2005 Caruso-Neves C, Kwon SH, Guggino WB. Albumin endocytosis in proximal tubule cells is modulated by angiotensin II through an AT2 receptor-mediated protein kinase B activation. Proceedings of the National Academy of Sciences of the United States of America. 102: 17513-8. PMID 16293694 DOI: 10.1073/Pnas.0507255102  0.663
2005 Li Y, Wright JM, Qian F, Germino GG, Guggino WB. Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling. The Journal of Biological Chemistry. 280: 41298-306. PMID 16223735 DOI: 10.1074/Jbc.M510082200  0.343
2005 Flotte TR, Schwiebert EM, Zeitlin PL, Carter BJ, Guggino WB. Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapy. Human Gene Therapy. 16: 921-8. PMID 16076250 DOI: 10.1089/Hum.2005.16.921  0.374
2005 Wang Y, Cai H, Cebotaru L, Hryciw DH, Weinman EJ, Donowitz M, Guggino SE, Guggino WB. ClC-5: role in endocytosis in the proximal tubule. American Journal of Physiology. Renal Physiology. 289: F850-62. PMID 15942052 DOI: 10.1152/Ajprenal.00011.2005  0.572
2005 Hara-Chikuma M, Wang Y, Guggino SE, Guggino WB, Verkman AS. Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. Biochemical and Biophysical Research Communications. 329: 941-6. PMID 15752747 DOI: 10.1016/J.Bbrc.2005.02.060  0.512
2005 Cheng J, Wang H, Guggino WB. Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10. The Journal of Biological Chemistry. 280: 3731-9. PMID 15546864 DOI: 10.1074/Jbc.M410026200  0.409
2005 Lewis HA, Zhao X, Wang C, Sauder JM, Rooney I, Noland BW, Lorimer D, Kearins MC, Conners K, Condon B, Maloney PC, Guggino WB, Hunt JF, Emtage S. Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure. The Journal of Biological Chemistry. 280: 1346-53. PMID 15528182 DOI: 10.1074/Jbc.M410968200  0.379
2004 Guggino WB. The cystic fibrosis transmembrane regulator forms macromolecular complexes with PDZ domain scaffold proteins. Proceedings of the American Thoracic Society. 1: 28-32. PMID 16113408 DOI: 10.1513/pats.2306011  0.309
2004 Kwon SH, Guggino WB. Multiple sequences in the C terminus of MaxiK channels are involved in expression, movement to the cell surface, and apical localization. Proceedings of the National Academy of Sciences of the United States of America. 101: 15237-42. PMID 15469924 DOI: 10.1073/Pnas.0404877101  0.703
2004 Guggino WB, Banks-Schlegel SP. Macromolecular interactions and ion transport in cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 170: 815-20. PMID 15447951 DOI: 10.1164/Rccm.200403-381Ws  0.401
2004 Sirninger J, Muller C, Braag S, Tang Q, Yue H, Detrisac C, Ferkol T, Guggino WB, Flotte TR. Functional characterization of a recombinant adeno-associated virus 5-pseudotyped cystic fibrosis transmembrane conductance regulator vector Human Gene Therapy. 15: 832-841. PMID 15353038 DOI: 10.1089/Hum.2004.15.832  0.362
2004 Zeitlin PL, Boyle MP, Guggino WB, Molina L. A phase I trial of intranasal Moli1901 for cystic fibrosis. Chest. 125: 143-9. PMID 14718433 DOI: 10.1378/Chest.125.1.143  0.339
2004 Lewis HA, Buchanan SG, Burley SK, Conners K, Dickey M, Dorwart M, Fowler R, Gao X, Guggino WB, Hendrickson WA, Hunt JF, Kearins MC, Lorimer D, Maloney PC, Post KW, et al. Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator. The Embo Journal. 23: 282-93. PMID 14685259 DOI: 10.1038/Sj.Emboj.7600040  0.369
2004 Wright JM, Zeitlin PL, Cebotaru L, Guggino SE, Guggino WB. Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins. Physiological Genomics. 16: 204-11. PMID 14583596 DOI: 10.1152/Physiolgenomics.00160.2003  0.381
2004 Cheng J, Wang H, Guggino WB. Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CAL. The Journal of Biological Chemistry. 279: 1892-8. PMID 14570915 DOI: 10.1074/Jbc.M308640200  0.429
2004 Fischer AC, Smith CI, Flotte TR, Guggino WB. 493. Enhanced Transgene Transfer and Expression by an Endobronchially Delivered Pseudotyped AAV2/5 Vector Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.412  0.31
2004 Munson KL, Tatalick LM, Smith CI, Fischer AC, Anklesaria P, Carter BJ, Guggino WB. 489. Comparison of AAV2 and AAV2/5 CFTR vectors in the lungs of cynomolgus macaques Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.399  0.367
2003 Santos Ornellas D, Grozovsky R, Goldenberg RC, Carvalho DP, Fong P, Guggino WB, Morales M. Thyroid hormone modulates CIC-2 chloride channel gene expression in rat renal proximal tubules Journal of Endocrinology. 178: 503-511. PMID 12967341 DOI: 10.1677/Joe.0.1780503  0.325
2003 Hryciw DH, Wang Y, Devuyst O, Pollock CA, Poronnik P, Guggino WB. Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines Journal of Biological Chemistry. 278: 40169-40176. PMID 12904289 DOI: 10.1074/Jbc.M307890200  0.509
2003 Christensen EI, Devuyst O, Dom G, Nielsen R, Van der Smissen P, Verroust P, Leruth M, Guggino WB, Courtoy PJ. Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules. Proceedings of the National Academy of Sciences of the United States of America. 100: 8472-7. PMID 12815097 DOI: 10.1073/Pnas.1432873100  0.353
2003 Nascimento DS, Reis CU, Goldenberg RC, Ortiga-Carvalho TM, Pazos-Moura CC, Guggino SE, Guggino WB, Morales MM. Estrogen modulates ClC-2 chloride channel gene expression in rat kidney. PflüGers Archiv : European Journal of Physiology. 446: 593-9. PMID 12811561 DOI: 10.1007/S00424-003-1095-Y  0.355
2003 Fong P, Argent BE, Guggino WB, Gray MA. Characterization of vectorial chloride transport pathways in the human pancreatic duct adenocarcinoma cell line HPAF. American Journal of Physiology. Cell Physiology. 285: C433-45. PMID 12711595 DOI: 10.1152/Ajpcell.00509.2002  0.408
2003 Wang SX, Ikeda M, Guggino WB. The cytoplasmic tail of large conductance, voltage- and Ca2+-activated K+ (MaxiK) channel is necessary for its cell surface expression. The Journal of Biological Chemistry. 278: 2713-22. PMID 12438308 DOI: 10.1074/Jbc.M208411200  0.412
2002 Devuyst O, Guggino WB. Chloride channels in the kidney: lessons learned from knockout animals. American Journal of Physiology. Renal Physiology. 283: F1176-91. PMID 12426234 DOI: 10.1152/Ajprenal.00184.2002  0.405
2002 Lebeau C, Hanaoka K, Moore-Hoon ML, Guggino WB, Beauwens R, Devuyst O. Basolateral chloride transporters in autosomal dominant polycystic kidney disease. PflüGers Archiv : European Journal of Physiology. 444: 722-31. PMID 12355171 DOI: 10.1007/s00424-002-0880-3  0.301
2002 Ikeda M, Guggino WB. Do polycystins function as cation channels? Current Opinion in Nephrology and Hypertension. 11: 539-45. PMID 12187319 DOI: 10.1097/00041552-200209000-00010  0.33
2002 Ikeda M, Beitz E, Kozono D, Guggino WB, Agre P, Yasui M. Characterization of aquaporin-6 as a nitrate channel in mammalian cells. Requirement of pore-lining residue threonine 63. The Journal of Biological Chemistry. 277: 39873-9. PMID 12177001 DOI: 10.1074/Jbc.M207008200  0.388
2002 Hazama A, Kozono D, Guggino WB, Agre P, Yasui M. Ion permeation of AQP6 water channel protein. Single channel recordings after Hg2+ activation. The Journal of Biological Chemistry. 277: 29224-30. PMID 12034750 DOI: 10.1074/Jbc.M204258200  0.353
2002 Ornellas DS, Nascimento DS, Christoph DH, Guggino WB, Morales MM. Aldosterone and high-NaCl diet modulate ClC-2 chloride channel gene expression in rat kidney. PflüGers Archiv : European Journal of Physiology. 444: 193-201. PMID 11976932 DOI: 10.1007/S00424-002-0788-Y  0.373
2002 Ketchum CJ, Yue H, Alessi KA, Devidas S, Guggino WB, Maloney PC. Intracellular cysteines of the cystic fibrosis transmembrane conductance regulator (CFTR) modulate channel gating. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 12: 1-8. PMID 11914543 DOI: 10.1159/000047821  0.435
2002 Schwiebert EM, Wallace DP, Braunstein GM, King SR, Peti-Peterdi J, Hanaoka K, Guggino WB, Guay-Woodford LM, Bell PD, Sullivan LP, Grantham JJ, Taylor AL. Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys. American Journal of Physiology. Renal Physiology. 282: F763-75. PMID 11880338 DOI: 10.1152/Ajprenal.0337.2000  0.391
2002 Edmonds RD, Silva IV, Guggino WB, Butler RB, Zeitlin PL, Blaisdell CJ. ClC-5: ontogeny of an alternative chloride channel in respiratory epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L501-7. PMID 11839544 DOI: 10.1152/Ajplung.00207.2001  0.375
2002 Morales MM, Nascimento DS, Capella MA, Lopes AG, Guggino WB. Arginine vasopressin regulates CFTR and ClC-2 mRNA expression in rat kidney cortex and medulla. Pflugers Archiv : European Journal of Physiology. 443: 202-11. PMID 11713645 DOI: 10.1007/S004240100671  0.369
2002 Cheng J, Moyer BD, Milewski M, Loffing J, Ikeda M, Mickle JE, Cutting GR, Li M, Stanton BA, Guggino WB. A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression. The Journal of Biological Chemistry. 277: 3520-9. PMID 11707463 DOI: 10.1074/Jbc.M110177200  0.382
2002 Boletta A, Qian F, Onuchic LF, Bhunia AK, Phakdeekitcharoen B, Hanaoka K, Guggino W, Monaco L, Germino GG. Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells. Molecular Cell. 6: 1267-73. PMID 11106764 DOI: 10.1016/S1097-2765(00)00123-4  0.348
2001 Boyle MP, Enke RA, Adams RJ, Guggino WB, Zeitlin PL. In utero AAV-mediated gene transfer to rabbit pulmonary epithelium. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 115-21. PMID 11482982 DOI: 10.1006/Mthe.2001.0428  0.333
2001 Guggino WB. Cystic fibrosis salt/fluid controversy: in the thick of it. Nature Medicine. 7: 888-9. PMID 11479614 DOI: 10.1038/90914  0.319
2001 Hanaoka K, Qian F, Boletta A, Bhunia AK, Piontek K, Tsiokas L, Sukhatme VP, Guggino WB, Germino GG. Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents. Nature. 408: 990-4. PMID 11140688 DOI: 10.1038/35050128  0.385
2001 Hryciw DH, Guggino WB. Cystic fibrosis transmembrane conductance regulator and the outwardly rectifying chloride channel: a relationship between two chloride channels expressed in epithelial cells. Clinical and Experimental Pharmacology & Physiology. 27: 892-5. PMID 11071305 DOI: 10.1046/J.1440-1681.2000.03356.X  0.421
2000 Wang SS, Devuyst O, Courtoy PJ, Wang XT, Wang H, Wang Y, Thakker RV, Guggino S, Guggino WB. Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis. Human Molecular Genetics. 9: 2937-45. PMID 11115837 DOI: 10.1093/Hmg/9.20.2937  0.522
2000 Wang S, Yue H, Derin RB, Guggino WB, Li M. Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity. Cell. 103: 169-79. PMID 11051556 DOI: 10.1016/S0092-8674(00)00096-9  0.431
2000 Guggino WB, Guggino SE. Amiloride-sensitive sodium channels contribute to the woes of the flu. Proceedings of the National Academy of Sciences of the United States of America. 97: 9827-9. PMID 10963654 DOI: 10.1073/Pnas.97.18.9827  0.335
2000 Moyer BD, Duhaime M, Shaw C, Denton J, Reynolds D, Karlson KH, Pfeiffer J, Wang S, Mickle JE, Milewski M, Cutting GR, Guggino WB, Li M, Stanton BA. The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane. The Journal of Biological Chemistry. 275: 27069-74. PMID 10852925 DOI: 10.1074/Jbc.M004951200  0.373
2000 Yue H, Devidas S, Guggino WB. The two halves of CFTR form a dual-pore ion channel. The Journal of Biological Chemistry. 275: 10030-4. PMID 10744680 DOI: 10.1074/Jbc.275.14.10030  0.366
2000 Silva IV, Blaisdell CJ, Guggino SE, Guggino WB. PTH regulates expression of ClC-5 chloride channel in the kidney. American Journal of Physiology. Renal Physiology. 278: F238-45. PMID 10662728 DOI: 10.1152/Ajprenal.2000.278.2.F238  0.305
2000 Hanaoka K, Wright JM, Cheglakov IB, Morita T, Guggino WB. A 59 amino acid insertion increases Ca(2+) sensitivity of rbslo1, a Ca2+ -activated K(+) channel in renal epithelia. The Journal of Membrane Biology. 172: 193-201. PMID 10568789 DOI: 10.1007/S002329900596  0.333
1999 Wagner JA, Messner AH, Moran ML, Daifuku R, Kouyama K, Desch JK, Manley S, Norbash AM, Conrad CK, Friborg S, Reynolds T, Guggino WB, Moss RB, Carter BJ, Wine JJ, et al. Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus. The Laryngoscope. 109: 266-74. PMID 10890777 DOI: 10.1097/00005537-199902000-00017  0.304
1999 Moyer BD, Denton J, Karlson KH, Reynolds D, Wang S, Mickle JE, Milewski M, Cutting GR, Guggino WB, Li M, Stanton BA. A PDZ-interacting domain in CFTR is an apical membrane polarization signal. The Journal of Clinical Investigation. 104: 1353-61. PMID 10562297 DOI: 10.1172/Jci7453  0.399
1999 Beck SE, Jones LA, Chesnut K, Walsh SM, Reynolds TC, Carter BJ, Askin FB, Flotte TR, Guggino WB. Repeated delivery of adeno-associated virus vectors to the rabbit airway. Journal of Virology. 73: 9446-55. PMID 10516053 DOI: 10.1128/Jvi.73.11.9446-9455.1999  0.315
1999 Guggino WB. Cystic fibrosis and the salt controversy. Cell. 96: 607-10. PMID 10089875 DOI: 10.1016/S0092-8674(00)80570-X  0.324
1999 Schwiebert EM, Benos DJ, Egan ME, Stutts MJ, Guggino WB. CFTR is a conductance regulator as well as a chloride channel. Physiological Reviews. 79: S145-66. PMID 9922379 DOI: 10.1152/Physrev.1999.79.1.S145  0.387
1998 Guggino WB. Focus on "Exocytosis is not involved in activation of Clsecretion via CFTR in Calu-3 airway epithelial cells". American Journal of Physiology. Cell Physiology. 275: C911-C912. PMID 29585297 DOI: 10.1152/Ajpcell.1998.275.4.C911  0.399
1998 Taylor AL, Kudlow BA, Marrs KL, Gruenert DC, Guggino WB, Schwiebert EM. Bioluminescence detection of ATP release mechanisms in epithelia. The American Journal of Physiology. 275: C1391-406. PMID 9814989 DOI: 10.1152/Ajpcell.1998.275.5.C1391  0.325
1998 Jiang Q, Mak D, Devidas S, Schwiebert EM, Bragin A, Zhang Y, Skach WR, Guggino WB, Foskett JK, Engelhardt JF. Cystic fibrosis transmembrane conductance regulator-associated ATP release is controlled by a chloride sensor. The Journal of Cell Biology. 143: 645-57. PMID 9813087 DOI: 10.1083/Jcb.143.3.645  0.403
1998 Devidas S, Yue H, Guggino WB. The second half of the cystic fibrosis transmembrane conductance regulator forms a functional chloride channel. The Journal of Biological Chemistry. 273: 29373-80. PMID 9792638 DOI: 10.1074/Jbc.273.45.29373  0.371
1998 Tsukaguchi H, Shayakul C, Berger UV, Mackenzie B, Devidas S, Guggino WB, van Hoek AN, Hediger MA. Molecular characterization of a broad selectivity neutral solute channel. The Journal of Biological Chemistry. 273: 24737-43. PMID 9733774 DOI: 10.1074/Jbc.273.38.24737  0.318
1998 Schwiebert EM, Egan ME, Guggino WB. Assays of dynamics, mechanisms, and regulation of ATP transport and release: implications for study of ABC transporter function. Methods in Enzymology. 292: 664-75. PMID 9711590 DOI: 10.1016/S0076-6879(98)92051-1  0.326
1998 Moyer BD, Loffing J, Schwiebert EM, Loffing-Cueni D, Halpin PA, Karlson KH, Ismailov II, Guggino WB, Langford GM, Stanton BA. Membrane trafficking of the cystic fibrosis gene product, cystic fibrosis transmembrane conductance regulator, tagged with green fluorescent protein in Madin-Darby canine kidney cells Journal of Biological Chemistry. 273: 21759-21768. PMID 9705313 DOI: 10.1074/Jbc.273.34.21759  0.408
1998 Wang S, Raab RW, Schatz PJ, Guggino WB, Li M. Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR). Febs Letters. 427: 103-8. PMID 9613608 DOI: 10.1016/S0014-5793(98)00402-5  0.338
1998 Schwiebert EM, Cid-Soto LP, Stafford D, Carter M, Blaisdell CJ, Zeitlin PL, Guggino WB, Cutting GR. Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 3879-84. PMID 9520461 DOI: 10.1073/Pnas.95.7.3879  0.408
1998 Mickle JE, Macek M, Fulmer-Smentek SB, Egan MM, Schwiebert E, Guggino W, Moss R, Cutting GR. A mutation in the cystic fibrosis transmembrane conductance regulator gene associated with elevated sweat chloride concentrations in the absence of cystic fibrosis. Human Molecular Genetics. 7: 729-35. PMID 9499426 DOI: 10.1093/Hmg/7.4.729  0.401
1998 Woo JS, Inoue CN, Hanaoka K, Schwiebert EM, Guggino SE, Guggino WB. Adenylyl cyclase is involved in desensitization and recovery of ATP-stimulated Cl- secretion in MDCK cells. The American Journal of Physiology. 274: C371-8. PMID 9486126 DOI: 10.1152/Ajpcell.1998.274.2.C371  0.333
1998 Schwiebert EM, Morales MM, Devidas S, Egan ME, Guggino WB. Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator. Proceedings of the National Academy of Sciences of the United States of America. 95: 2674-9. PMID 9482946 DOI: 10.1073/Pnas.95.5.2674  0.431
1997 McNicholas CM, Nason MW, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. A functional CFTR-NBF1 is required for ROMK2-CFTR interaction. American Journal of Physiology. Renal Physiology. 273: F843-F848. PMID 29587108 DOI: 10.1152/ajprenal.1997.273.5.F843  0.301
1997 Morita T, Hanaoka K, Morales MM, Montrose-Rafizadeh C, Guggino WB. Cloning and characterization of maxi Kchannel α-subunit in rabbit kidney. American Journal of Physiology. Renal Physiology. 273: F615-F624. PMID 29587095 DOI: 10.1152/Ajprenal.1997.273.4.F615  0.336
1997 McNicholas CM, Nason MW, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. A functional CFTR-NBF1 is required for ROMK2-CFTR interaction. The American Journal of Physiology. 273: F843-8. PMID 9374850 DOI: 10.1152/Ajprenal.1997.273.5.F843  0.394
1997 Rubenstein RC, McVeigh U, Flotte TR, Guggino WB, Zeitlin PL. CFTR gene transduction in neonatal rabbits using an adeno-associated virus (AAV) vector. Gene Therapy. 4: 384-92. PMID 9274714 DOI: 10.1038/Sj.Gt.3300417  0.336
1997 Devidas S, Guggino WB. The cystic fibrosis transmembrane conductance regulator and ATP. Current Opinion in Cell Biology. 9: 547-52. PMID 9261051 DOI: 10.1016/S0955-0674(97)80032-4  0.384
1997 Inoue CN, Woo JS, Schwiebert EM, Morita T, Hanaoka K, Guggino SE, Guggino WB. Role of purinergic receptors in chloride secretion in Caco-2 cells. The American Journal of Physiology. 272: C1862-70. PMID 9227415 DOI: 10.1152/Ajpcell.1997.272.6.C1862  0.36
1997 Xu XZ, Li HS, Guggino WB, Montell C. Coassembly of TRP and TRPL produces a distinct store-operated conductance. Cell. 89: 1155-64. PMID 9215637 DOI: 10.1016/S0092-8674(00)80302-5  0.328
1997 Devuyst O, Golstein PE, Sanches MV, Piontek K, Wilson PD, Guggino WB, Dumont JE, Beauwens R. Expression of CFTR in human and bovine thyroid epithelium. The American Journal of Physiology. 272: C1299-308. PMID 9142856 DOI: 10.1152/Ajpcell.1997.272.4.C1299  0.389
1997 Schwiebert EM, Potter ED, Hwang TH, Woo JS, Ding C, Qiu W, Guggino WB, Levine MA, Guggino SE. CGMP stimulates sodium and chloride currents in rat tracheal airway epithelia American Journal of Physiology - Cell Physiology. 272: C911-C922. PMID 9124527 DOI: 10.1152/Ajpcell.1997.272.3.C911  0.384
1997 Mogayzel PJ, Henning KA, Bittner ML, Novotny EA, Schwiebert EM, Guggino WB, Jiang Y, Rosenfeld MA. Functional human CFTR produced by stable Chinese hamster ovary cell lines derived using yeast artificial chromosomes. Human Molecular Genetics. 6: 59-68. PMID 9002671 DOI: 10.1093/Hmg/6.1.59  0.392
1996 Devuyst O, Burrow CR, Schwiebert EM, Guggino WB, Wilson PD. Developmental regulation of CFTR expression during human nephrogenesis. The American Journal of Physiology. 271: F723-35. PMID 8853436 DOI: 10.1152/Ajprenal.1996.271.3.F723  0.386
1996 Hanaoka K, Devuyst O, Schwiebert EM, Wilson PD, Guggino WB. A role for CFTR in human autosomal dominant polycystic kidney disease. The American Journal of Physiology. 270: C389-99. PMID 8772467 DOI: 10.1152/Ajpcell.1996.270.1.C389  0.401
1996 Morales MM, Carroll TP, Morita T, Schwiebert EM, Devuyst O, Wilson PD, Lopes AG, Stanton BA, Dietz HC, Cutting GR, Guggino WB. Both the wild type and a functional isoform of CFTR are expressed in kidney. The American Journal of Physiology. 270: F1038-48. PMID 8764323 DOI: 10.1152/Ajprenal.1996.270.6.F1038  0.425
1996 Hwang TH, Schwiebert EM, Guggino WB. Apical and basolateral ATP stimulates tracheal epithelial chloride secretion via multiple purinergic receptors American Journal of Physiology - Cell Physiology. 270: C1611-C1623. PMID 8764143 DOI: 10.1152/Ajpcell.1996.270.6.C1611  0.397
1996 McNicholas CM, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. Proceedings of the National Academy of Sciences of the United States of America. 93: 8083-8. PMID 8755607 DOI: 10.1073/Pnas.93.15.8083  0.405
1996 Calamita G, Bishai WR, Preston GM, Guggino WB, Agre P. Molecular cloning and characterization of AqpZ, a water channel from Escherichia coli. The Journal of Biological Chemistry. 270: 29063-6. PMID 7493926 DOI: 10.1074/Jbc.270.49.29063  0.328
1995 Cid LP, Montrose-Rafizadeh C, Smith DI, Guggino WB, Cutting GR. Cloning of a putative human voltage-gated chloride channel (CIC-2) cDNA widely expressed in human tissues. Human Molecular Genetics. 4: 407-13. PMID 7795595 DOI: 10.1093/Hmg/4.3.407  0.361
1995 Bredt DS, Wang TL, Cohen NA, Guggino WB, Snyder SH. Cloning and expression of two brain-specific inwardly rectifying potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 92: 6753-7. PMID 7624316 DOI: 10.1073/Pnas.92.15.6753  0.324
1995 Fulmer SB, Schwiebert EM, Morales MM, Guggino WB, Cutting GR. Two cystic fibrosis transmembrane conductance regulator mutations have different effects on both pulmonary phenotype and regulation of outwardly rectified chloride currents. Proceedings of the National Academy of Sciences of the United States of America. 92: 6832-6. PMID 7542778 DOI: 10.1073/Pnas.92.15.6832  0.433
1995 Schwiebert EM, Egan ME, Hwang TH, Fulmer SB, Allen SS, Cutting GR, Guggino WB. CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell. 81: 1063-73. PMID 7541313 DOI: 10.1016/S0092-8674(05)80011-X  0.432
1995 Carroll TP, Morales MM, Fulmer SB, Allen SS, Flotte TR, Cutting GR, Guggino WB. Alternate translation initiation codons can create functional forms of cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 270: 11941-6. PMID 7538127 DOI: 10.1074/Jbc.270.20.11941  0.385
1995 Mulders SM, Preston GM, Deen PMT, Guggino WB, Van Os CH, Agre P. Water channel properties of major intrinsic protein of lens Journal of Biological Chemistry. 270: 9010-9016. PMID 7536742 DOI: 10.1074/Jbc.270.15.9010  0.372
1995 Egan ME, Schwiebert EM, Guggino WB. Differential expression of ORCC and CFTR induced by low temperature in CF airway epithelial cells. The American Journal of Physiology. 268: C243-51. PMID 7530908 DOI: 10.1152/Ajpcell.1995.268.1.C243  0.336
1995 Raina S, Preston GM, Guggino WB, Agre P. Molecular cloning and characterization of an aquaporin cDNA from salivary, lacrimal, and respiratory tissues. The Journal of Biological Chemistry. 270: 1908-12. PMID 7530250 DOI: 10.1074/Jbc.270.4.1908  0.337
1994 Jung JS, Bhat RV, Preston GM, Guggino WB, Baraban JM, Agre P. Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance. Proceedings of the National Academy of Sciences of the United States of America. 91: 13052-6. PMID 7528931 DOI: 10.1073/Pnas.91.26.13052  0.33
1994 Schwiebert EM, Flotte T, Cutting GR, Guggino WB. Both CFTR and outwardly rectifying chloride channels contribute to cAMP- stimulated whole cell chloride currents American Journal of Physiology - Cell Physiology. 266. PMID 7515570 DOI: 10.1152/Ajpcell.1994.266.5.C1464  0.427
1994 Rao MC, Bissonnette GB, Mahaffey T, Guggino WB, Goldstein JL. Rectal epithelial expression of protein kinase A phosphorylation of cystic fibrosis transmembrane conductance regulator. Gastroenterology. 106: 890-8. PMID 7511554 DOI: 10.1016/0016-5085(94)90747-1  0.344
1994 Carroll TP, McIntosh I, Egan ME, Zeitlin PL, Cutting GR, Guggino WB. Transmembrane mutations alter the channel characteristics of the cystic fibrosis transmembrane conductance regulator expressed in Xenopus oocytes Cellular Physiology and Biochemistry. 4: 10-18. DOI: 10.1159/000154705  0.365
1994 Schwiebert EM, Lopes AG, Guggino WB. Chapter 10 Chloride Channels along the Nephron Current Topics in Membranes. 42: 265-315. DOI: 10.1016/S0070-2161(08)60825-4  0.37
1993 Lu L, Yang T, Markakis D, Guggino WB, Craig RW. Alterations in a voltage-gated K+ current during the differentiation of ML-1 human myeloblastic leukemia cells. The Journal of Membrane Biology. 132: 267-74. PMID 8492309 DOI: 10.1007/Bf00235743  0.309
1993 Agre P, Preston GM, Smith BL, Jung JS, Raina S, Moon C, Guggino WB, Nielsen S. Aquaporin CHIP: the archetypal molecular water channel. The American Journal of Physiology. 265: F463-76. PMID 7694481 DOI: 10.1152/Ajprenal.1993.265.4.F463  0.319
1993 Lu L, Markakis D, Guggino WB. Identification and regulation of whole-cell Cl- and Ca(2+)-activated K+ currents in cultured medullary thick ascending limb cells. The Journal of Membrane Biology. 135: 181-9. PMID 7692066 DOI: 10.1007/Bf00231443  0.342
1993 Guggino WB. Outwardly rectifying chloride channels and CF: a divorce and remarriage. Journal of Bioenergetics and Biomembranes. 25: 27-35. PMID 7680029 DOI: 10.1007/Bf00768065  0.388
1993 Flotte TR, Afione SA, Conrad C, McGrath SA, Solow R, Oka H, Zeitlin PL, Guggino WB, Carter BJ. Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector. Proceedings of the National Academy of Sciences of the United States of America. 90: 10613-7. PMID 7504271 DOI: 10.1073/Pnas.90.22.10613  0.351
1993 Carroll TP, Schwiebert EM, Guggino WB. CFTR: Structure and Function Cellular Physiology and Biochemistry. 3: 388-399. DOI: 10.1159/000154700  0.311
1992 Egan M, Flotte T, Afione S, Solow R, Zeitlin PL, Carter BJ, Guggino WB. Defective regulation of outwardly rectifying Cl- channels by protein kinase a corrected by insertion of CFTR Nature. 358: 581-584. PMID 1380129 DOI: 10.1038/358581A0  0.43
1992 Preston GM, Carroll TP, Guggino WB, Agre P. Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science (New York, N.Y.). 256: 385-7. PMID 1373524 DOI: 10.1126/Science.256.5055.385  0.347
1992 Bargon J, Trapnell BC, Chu CS, Rosenthal ER, Yoshimura K, Guggino WB, Dalemans W, Pavirani A, Lecocq JP, Crystal RG. Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations. Molecular and Cellular Biology. 12: 1872-8. PMID 1372390 DOI: 10.1128/Mcb.12.4.1872  0.411
1992 Hwang TC, Egan ME, Guggino WB. Kinetic interaction of fatty acids with outwardly rectifying chloride channels Cellular Physiology and Biochemistry. 2: 308-315. DOI: 10.1159/000154653  0.354
1991 Montrose-Rafizadeh C, Guggino WB. Role of intracellular calcium in volume regulation by rabbit medullary thick ascending limb cells. The American Journal of Physiology. 260: F402-9. PMID 1900390 DOI: 10.1152/Ajprenal.1991.260.3.F402  0.334
1991 Hwang TC, Guggino WB. Regulation of epithelial chloride channels: roles of protein kinases and arachidonic acid. Advances in Experimental Medicine and Biology. 290: 209-23; discussion 2. PMID 1719759 DOI: 10.1007/978-1-4684-5934-0_21  0.348
1991 Crawford I, Maloney PC, Zeitlin PL, Guggino WB, Hyde SC, Turley H, Gatter KC, Harris A, Higgins CF. Immunocytochemical localization of the cystic fibrosis gene product CFTR Proceedings of the National Academy of Sciences of the United States of America. 88: 9262-9266. PMID 1718002 DOI: 10.1073/Pnas.88.20.9262  0.426
1991 Lu L, Markakis D, Guggino WB. Blockade of Ca2+-Dependent Cl– Current in Xenopus Oocytes by C– Channel Blockers and Antimalarial Drugs Cellular Physiology and Biochemistry. 1: 251-262. DOI: 10.1159/000154613  0.34
1990 Montrose-Rafizadeh C, Guggino WB. Cell volume regulation in the nephron. Annual Review of Physiology. 52: 761-72. PMID 2158770 DOI: 10.1146/Annurev.Ph.52.030190.003553  0.357
1990 Guggino WB. In Reply: Chloride Channels in Cystic Fibrosis Patients Science. 247: 222-222. DOI: 10.1126/Science.247.4939.222-A  0.342
1989 Cornejo M, Guggino SE, Guggino WB. Ca2+-activated K+ channels from cultured renal medullary thick ascending limb cells: effects of pH. The Journal of Membrane Biology. 110: 49-55. PMID 2795640 DOI: 10.1007/Bf01870992  0.348
1989 Taniguchi J, Guggino WB. Membrane stretch: a physiological stimulator of Ca2+-activated K+ channels in thick ascending limb. The American Journal of Physiology. 257: F347-52. PMID 2782419 DOI: 10.1152/Ajprenal.1989.257.3.F347  0.345
1989 Lu L, Zeitlin PL, Guggino WB, Craig RW. Gene transfer by lipofection in rabbit and human secretory epithelial cells PflüGers Archiv European Journal of Physiology. 415: 198-203. PMID 2594476 DOI: 10.1007/Bf00370592  0.32
1989 Hwang TC, Lu L, Zeitlin PL, Gruenert DC, Huganir R, Guggino WB. C1- channels in CF: Lack of activation by protein kinase C and cAMP-dependent protein kinase Science. 244: 1351-1353. PMID 2472005 DOI: 10.1126/Science.2472005  0.391
1988 Lopes AG, Guggino WB. Volume regulation in the early proximal tubule of the Necturus kidney. The Journal of Membrane Biology. 97: 117-25. PMID 3446818 DOI: 10.1007/Bf01869418  0.33
1988 Lopes AG, Amzel LM, Markakis D, Guggino WB. Cell volume regulation by the thin descending limb of Henle's loop Proceedings of the National Academy of Sciences of the United States of America. 85: 2873-2877. PMID 2833759 DOI: 10.1073/Pnas.85.8.2873  0.334
1985 Guggino WB, Oberleithner H, Giebisch G. Relationship between cell volume and ion transport in the early distal tubule of the Amphiuma kidney. The Journal of General Physiology. 86: 31-58. PMID 2411847 DOI: 10.1085/Jgp.86.1.31  0.328
1983 Oberleithner H, Ritter M, Lang F, Guggino W. Anthracene-9-carboxylic acid inhibits renal chloride reabsorption. Pflugers Archiv : European Journal of Physiology. 398: 172-4. PMID 6604902 DOI: 10.1007/Bf00581068  0.327
Low-probability matches (unlikely to be authored by this person)
1989 Zeitlin PL, Wagner M, Markakis D, Loughlin GM, Guggino WB. Steroid hormones: modulators of Na+ absorption and Cl- secretion in cultured tracheal epithelia. Proceedings of the National Academy of Sciences of the United States of America. 86: 2502-5. PMID 2928347 DOI: 10.1073/Pnas.86.7.2502  0.3
1991 Cutting GR, Lu L, O'Hara BF, Kasch LM, Montrose-Rafizadeh C, Donovan DM, Shimada S, Antonarakis SE, Guggino WB, Uhl GR. Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina. Proceedings of the National Academy of Sciences of the United States of America. 88: 2673-7. PMID 1849271 DOI: 10.1073/Pnas.88.7.2673  0.298
2020 Guggino WB, Yanda MK, Cebotaru CV, Cebotaru L. Transduction of Surface and Basal Cells in Rhesus Macaque Lung Following Repeat Dosing with AAV1CFTR. Human Gene Therapy. 31: 1010-1023. PMID 32862701 DOI: 10.1089/Hum.2020.207  0.298
2005 Cebotaru V, Kaul S, Devuyst O, Cai H, Racusen L, Guggino WB, Guggino SE. High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease. Kidney International. 68: 642-52. PMID 16014041 DOI: 10.1111/J.1523-1755.2005.00442.X  0.297
1992 Egan ME, Wagner MH, Zeitlin PL, Guggino WB. Modulation of ion transport in cultured rabbit tracheal epithelium by lipoxygenase metabolites. American Journal of Respiratory Cell and Molecular Biology. 7: 500-6. PMID 1419026 DOI: 10.1165/Ajrcmb/7.5.500  0.296
1997 Inoue CN, Ko YH, Guggino WB, Forster HG, Epstein M. Lysophosphatidic acid and platelet-derived growth factor synergistically stimulate growth of cultured rat mesangial cells. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 216: 370-9. PMID 9402141 DOI: 10.3181/00379727-216-44184  0.295
1997 Hackam AS, Wang TL, Guggino WB, Cutting GR. The N-terminal domain of human GABA receptor rho1 subunits contains signals for homooligomeric and heterooligomeric interaction. The Journal of Biological Chemistry. 272: 13750-7. PMID 9153229 DOI: 10.1074/Jbc.272.21.13750  0.293
1995 Wang T, Hackam A, Guggino W, Cutting G. A single histidine residue is essential for zinc inhibition of GABA rho 1 receptors. The Journal of Neuroscience. 15: 7684-7691. DOI: 10.1523/Jneurosci.15-11-07684.1995  0.293
1997 Hackam AS, Wang TL, Guggino WB, Cutting GR. A 100 amino acid region in the GABA rho 1 subunit confers robust homo-oligomeric expression. Neuroreport. 8: 1425-30. PMID 9172147 DOI: 10.1097/00001756-199704140-00020  0.292
2023 Yanda MK, Ciobanu C, Guggino WB, Cebotaru L. CFTR and PC2, partners in the primary cilia in autosomal dominant polycystic kidney disease. American Journal of Physiology. Cell Physiology. 325: C682-C693. PMID 37519231 DOI: 10.1152/ajpcell.00197.2023  0.292
1996 Afione SA, Conrad CK, Kearns WG, Chunduru S, Adams R, Reynolds TC, Guggino WB, Cutting GR, Carter BJ, Flotte TR. In vivo model of adeno-associated virus vector persistence and rescue. Journal of Virology. 70: 3235-41. PMID 8627804 DOI: 10.1128/Jvi.70.5.3235-3241.1996  0.291
1988 Guggino WB, Oberleithner H, Giebisch G. The amphibian diluting segment. The American Journal of Physiology. 254: F615-27. PMID 3284387 DOI: 10.1152/Ajprenal.1988.254.5.F615  0.291
2004 Karp CL, Flick LM, Park KW, Softic S, Greer TM, Keledjian R, Yang R, Uddin J, Guggino WB, Atabani SF, Belkaid Y, Xu Y, Whitsett JA, Accurso FJ, Wills-Karp M, et al. Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway. Nature Immunology. 5: 388-92. PMID 15034576 DOI: 10.1038/Ni1056  0.291
2010 Flotte TR, Fischer AC, Goetzmann J, Mueller C, Cebotaru L, Yan Z, Wang L, Wilson JM, Guggino WB, Engelhardt JF. Dual reporter comparative indexing of rAAV pseudotyped vectors in chimpanzee airway. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 594-600. PMID 19826405 DOI: 10.1038/Mt.2009.230  0.29
2009 Fan C, Su Q, Li Y, Liang L, Angelini DJ, Guggino WB, Johns RA. Hypoxia-induced mitogenic factor/FIZZ1 induces intracellular calcium release through the PLC-IP(3) pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L263-70. PMID 19429774 DOI: 10.1152/Ajplung.90416.2008  0.29
1999 Truong-Le VL, Walsh SM, Schweibert E, Mao HQ, Guggino WB, August JT, Leong KW. Gene transfer by DNA-gelatin nanospheres. Archives of Biochemistry and Biophysics. 361: 47-56. PMID 9882427 DOI: 10.1006/Abbi.1998.0975  0.289
2006 Boyle MP, Enke RA, Reynolds JB, Mogayzel PJ, Guggino WB, Zeitlin PL. Membrane-associated heparan sulfate is not required for rAAV-2 infection of human respiratory epithelia. Virology Journal. 3: 29. PMID 16630361 DOI: 10.1186/1743-422X-3-29  0.288
2018 Boinot C, Wang H, Sabirzhanova I, Cebotaru C, Guggino W, Cebotaru L. WS15.2 R334W CFTR, a severely compromised chloride conductance mutant, retains its bicarbonate conductance and responds to the corrector combination, C4 + C18 Journal of Cystic Fibrosis. 17: S27-S28. DOI: 10.1016/S1569-1993(18)30203-0  0.287
2017 Guggino WB, Cebotaru L. Adeno-Associated Virus (AAV) gene therapy for cystic fibrosis: current barriers and recent developments. Expert Opinion On Biological Therapy. PMID 28657358 DOI: 10.1080/14712598.2017.1347630  0.287
2007 Liu X, Luo M, Trygg C, Yan Z, Lei-Butters DC, Smith CI, Fischer AC, Munson K, Guggino WB, Bunnell BA, Engelhardt JF. Biological Differences in rAAV Transduction of Airway Epithelia in Humans and in Old World Non-human Primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 2114-23. PMID 17667945 DOI: 10.1038/Sj.Mt.6300277  0.284
1991 Zeitlin PL, Lu L, Rhim J, Cutting G, Stetten G, Kieffer KA, Craig R, Guggino WB. A cystic fibrosis bronchial epithelial cell line: immortalization by adeno-12-SV40 infection American Journal of Respiratory Cell and Molecular Biology. 4: 313-319. PMID 1849726 DOI: 10.1165/Ajrcmb/4.4.313  0.283
2003 Fischer AC, Beck SE, Smith CI, Laube BL, Askin FB, Guggino SE, Adams RJ, Flotte TR, Guggino WB. Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 918-26. PMID 14664794 DOI: 10.1016/J.Ymthe.2003.08.015  0.281
2005 Rebelo MA, Tostes V, Araújo NC, Martini SV, Botelho BF, Guggino WB, Morales MM. Screening for CLCN5 mutation in renal calcium stone formers patients. Anais Da Academia Brasileira De CiêNcias. 77: 95-101. PMID 15692680 DOI: 10.1590/S0001-37652005000100007  0.28
2004 Hryciw DH, Ekberg J, Lee A, Lensink IL, Kumar S, Guggino WB, Cook DI, Pollock CA, Poronnik P. Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells. The Journal of Biological Chemistry. 279: 54996-5007. PMID 15489223 DOI: 10.1074/Jbc.M411491200  0.28
2017 Guggino W, Benson J, Seagrave J, Yan Z, Engelhardt JF, Gao G, Conlon TJ, Cebotaru L. A PRECLINICAL STUDY IN RHESUS MACAQUES FOR CYSTIC FIBROSIS TO ASSESS GENE TRANSFER AND TRANSDUCTION BY AAV1 AND AAV5 WITH A DUAL-LUCIFERASE REPORTER SYSTEM. Human Gene Therapy. Clinical Development. PMID 28726496 DOI: 10.1089/Humc.2017.067  0.28
2014 Cebotaru L, Rapino D, Cebotaru V, Guggino WB. Correcting the cystic fibrosis disease mutant, A455E CFTR. Plos One. 9: e85183. PMID 24416359 DOI: 10.1371/Journal.Pone.0085183  0.279
2016 Yanda MK, Boinot C, Sabirzhanova I, Guggino W, Cebotaru L. Mo1284 C. difficile Toxin B Increases Chloride Secretion in CaCo2 Cells Gastroenterology. 150: S688. DOI: 10.1016/S0016-5085(16)32342-3  0.276
2020 Guggino WB, Cebotaru L. Gene Therapy for Cystic Fibrosis Paved the Way for the Use of Adeno-Associated Virus in Gene Therapy. Human Gene Therapy. 31: 538-541. PMID 32283956 DOI: 10.1089/Hum.2020.046  0.275
1990 Lu L, Montrose-Rafizadeh C, Hwang TC, Guggino WB. A delayed rectifier potassium current in Xenopus oocytes. Biophysical Journal. 57: 1117-23. PMID 2393700 DOI: 10.1016/S0006-3495(90)82632-1  0.274
2016 Cebotaru L, Cebotaru V, Wang H, Arend LJ, Guggino WB. STIM1fl/fl Ksp-Cre Mouse has Impaired Renal Water Balance. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 172-182. PMID 27336410 DOI: 10.1159/000445614  0.274
2002 Guggino W. ABC proteins as transport modifiers Kidney International. 62: 1519. DOI: 10.1046/J.1523-1755.2002.T01-7-00644.X  0.273
1996 Flotte T, Carter B, Conrad C, Guggino W, Reynolds T, Rosenstein B, Taylor G, Walden S, Wetzel R. A Phase I Study of an Adeno-Associated Virus-CFTR Gene Vector in Adult CF Patients with Mild Lung Disease. Johns Hopkins Children's Center, Baltimore, Maryland Human Gene Therapy. 7: 1145-1159. PMID 8773517 DOI: 10.1089/Hum.1996.7.9-1145  0.273
2016 Boinot C, Sabirzhanova I, Guggino W, Cebotaru L. Tu1463 The R122H Mutation Stabilizes the PRSS1 Protein in Pancreatitis Gastroenterology. 150: S908. DOI: 10.1016/S0016-5085(16)33076-1  0.272
2006 Rothwell SW, Eidelman O, Jozwik C, Mueller G, Poth M, Zeitlin PL, Guggino W, Jacobowitz DM, Srivastava M, Pollard HB. Signalling Pathways Have Different Expression Profiles in Human Platelets Isolated from Men and Women. Blood. 108: 1519-1519. DOI: 10.1182/Blood.V108.11.1519.1519  0.27
2016 de Lemos Barbosa CM, Souza-Menezes J, Amaral AG, Onuchic LF, Cebotaru L, Guggino WB, Morales MM. Regulation of CFTR Expression and Arginine Vasopressin Activity Are Dependent on Polycystin-1 in Kidney-Derived Cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 38: 28-39. PMID 26741910 DOI: 10.1159/000438606  0.27
2000 Morales MM, Capella MA, Sanches MV, Lopes AG, Guggino WB. Modulation of the mdr-1b gene in the kidney of rats subjected to dehydration or a high-salt diet. Pflugers Archiv : European Journal of Physiology. 439: 356-62. PMID 10650988 DOI: 10.1007/S004249900175  0.27
2002 Beck SE, Laube BL, Barberena CI, Fischer AC, Adams RJ, Chesnut K, Flotte TR, Guggino WB. Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 546-54. PMID 12387250 DOI: 10.1006/Mthe.2002.0698  0.268
1994 Wang T, Guggino W, Cutting G. A novel gamma-aminobutyric acid receptor subunit (rho 2) cloned from human retina forms bicuculline-insensitive homooligomeric receptors in Xenopus oocytes The Journal of Neuroscience. 14: 6524-6531. DOI: 10.1523/Jneurosci.14-11-06524.1994  0.267
2003 Boyle MP, Enke RA, Mogayzel PJ, Guggino WB, Martin DB, Agarwal S, Zeitlin PL. Effect of adeno-associated virus-specific immunoglobulin G in human amniotic fluid on gene transfer. Human Gene Therapy. 14: 365-73. PMID 12659677 DOI: 10.1089/104303403321208961  0.266
1991 Hollunder-Reese F, Mohrmann M, Bleich M, Greger R, Lu L, Markakis D, Guggino WB, Granitzer M, Lyoussi B, Nagel W, Crabbé J, Leipziger J, Nitschke R, Schäfer C, Westphale H, et al. Efraim Racker 1913-1991 Cellular Physiology and Biochemistry. 1: 237-237. DOI: 10.1159/000154611  0.266
1995 Guay-Broder C, Jacobson KA, Barnoy S, Cabantchik ZI, Guggino WB, Zeitlin PL, Turner RJ, Vergara L, Eidelman O, Pollard HB. A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine selectively activates chloride efflux from human epithelial and mouse fibroblast cell lines expressing the cystic fibrosis transmembrane regulator delta F508 mutation. Biochemistry. 34: 9079-87. PMID 7542476 DOI: 10.1021/bi00028a017  0.266
1995 Wang TL, Hackam AS, Guggino WB, Cutting GR. A single amino acid in gamma-aminobutyric acid rho 1 receptors affects competitive and noncompetitive components of picrotoxin inhibition. Proceedings of the National Academy of Sciences of the United States of America. 92: 11751-5. PMID 8524842 DOI: 10.1073/Pnas.92.25.11751  0.264
1995 Vandorpe D, Kizer N, Ciampollilo F, Moyer B, Karlson K, Guggino WB, Stanton BA. CFTR mediates electrogenic chloride secretion in mouse inner medullary collecting duct (mIMCD-K2) cells. The American Journal of Physiology. 269: C683-9. PMID 7573398 DOI: 10.1152/ajpcell.1995.269.3.C683  0.264
1992 Wiebke JL, Montrose-Rafizadeh C, Zeitlin PL, Guggino WB. Effect of hypoxia on endothelin-1 production by pulmonary vascular endothelial cells. Biochimica Et Biophysica Acta. 1134: 105-11. PMID 1554747 DOI: 10.1016/0167-4889(92)90033-8  0.263
2003 Silva IV, Cebotaru V, Wang H, Wang XT, Wang SS, Guo G, Devuyst O, Thakker RV, Guggino WB, Guggino SE. The ClC-5 knockout mouse model of Dent's disease has renal hypercalciuria and increased bone turnover. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 615-23. PMID 12674322 DOI: 10.1359/Jbmr.2003.18.4.615  0.262
2008 Lassance RM, Pássaro CP, Martini SV, Castiglione RC, Gutierrez TM, Abreu SC, Antunes MA, Xisto DG, Cebotaru L, Petrs-Silva H, Zin WA, Guggino WB, Linden R, Rocco PR, Morales MM. Does the use of recombinant AAV2 in pulmonary gene therapy damage lung function? Respiratory Physiology & Neurobiology. 160: 91-8. PMID 17950048 DOI: 10.1016/J.Resp.2007.09.002  0.262
1998 Hackam AS, Wang TL, Guggino WB, Cutting GR. Sequences in the amino termini of GABA rho and GABA(A) subunits specify their selective interaction in vitro. Journal of Neurochemistry. 70: 40-6. PMID 9422345 DOI: 10.1046/J.1471-4159.1998.70010040.X  0.26
1988 Zeitlin PL, Loughlin GM, Guggino WB. Ion transport in cultured fetal and adult rabbit tracheal epithelia. The American Journal of Physiology. 254: C691-8. PMID 2834958 DOI: 10.1152/Ajpcell.1988.254.5.C691  0.26
1998 Devidas S, Guggino WB. CFTR: domains, structure, and function. Journal of Bioenergetics and Biomembranes. 29: 443-51. PMID 9511929 DOI: 10.1023/A:1022430906284  0.26
1999 Schneider SW, Egan ME, Jena BP, Guggino WB, Oberleithner H, Geibel JP. Continuous detection of extracellular ATP on living cells by using atomic force microscopy. Proceedings of the National Academy of Sciences of the United States of America. 96: 12180-5. PMID 10518596 DOI: 10.1073/Pnas.96.21.12180  0.256
1998 Wagner JA, Moran ML, Messner AH, Daifuku R, Conrad CK, Reynolds T, Guggino WB, Moss RB, Carter BJ, Wine JJ, Flotte TR, Gardner P. A phase I/II study of tgAAV-CF for the treatment of chronic sinusitis in patients with cystic fibrosis. Human Gene Therapy. 9: 889-909. PMID 9581911 DOI: 10.1089/Hum.1998.9.6-889  0.253
1999 Afione SA, Wang J, Walsh S, Guggino WB, Flotte TR. Delayed expression of adeno-associated virus vector DNA Intervirology. 42: 213-220. PMID 10567839 DOI: 10.1159/000024980  0.251
1989 Hilden SA, Johns CA, Guggino WB, Madias NE. Techniques for isolation of brush-border and basolateral membrane vesicles from dog kidney cortex Biochimica Et Biophysica Acta. 983: 77-81. PMID 2758052 DOI: 10.1016/0005-2736(89)90382-9  0.25
1985 Guggino SE, Suarez-Isla BA, Guggino WB, Sacktor B. Forskolin and antidiuretic hormone stimulate a Ca2+-activated K+ channel in cultured kidney cells. The American Journal of Physiology. 249: F448-55. PMID 2412453 DOI: 10.1152/ajprenal.1985.249.3.F448  0.248
2007 Pollard HB, Srivastava M, Eidelman O, Jozwik C, Rothwell SW, Mueller GP, Jacobowitz DM, Darling T, Guggino WB, Wright J, Zeitlin PL, Paweletz CP. Protein microarray platforms for clinical proteomics. Proteomics. Clinical Applications. 1: 934-52. PMID 21136748 DOI: 10.1002/Prca.200700154  0.245
2016 Cebotaru L, Boinot C, Sabirzhanova I, Guggino W. 33 Rescue of premature stop mutations R1162X and W1282X by a combination of small molecule correctors Journal of Cystic Fibrosis. 15: S60. DOI: 10.1016/S1569-1993(16)30273-9  0.243
2002 Swiatecka-Urban A, Duhaime M, Coutermarsh B, Karlson KH, Collawn J, Milewski M, Cutting GR, Guggino WB, Langford G, Stanton BA. PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 277: 40099-105. PMID 12167629 DOI: 10.1074/Jbc.M206964200  0.241
1993 Kusama T, Wang TL, Guggino WB, Cutting GR, Uhl GR. GABA rho 2 receptor pharmacological profile: GABA recognition site similarities to rho 1. European Journal of Pharmacology. 245: 83-4. PMID 8386671 DOI: 10.1016/0922-4106(93)90174-8  0.24
1987 Guggino SE, Guggino WB, Green N, Sacktor B. Ca2+-activated K+ channels in cultured medullary thick ascending limb cells. The American Journal of Physiology. 252: C121-7. PMID 2435160 DOI: 10.1152/ajpcell.1987.252.2.C121  0.24
2004 Chikhlikar P, Barros de Arruda L, Agrawal S, Byrne B, Guggino W, August JT, Marques ET. Inverted terminal repeat sequences of adeno-associated virus enhance the antibody and CD8(+) responses to a HIV-1 p55Gag/LAMP DNA vaccine chimera. Virology. 323: 220-32. PMID 15193918 DOI: 10.1016/J.Virol.2004.02.025  0.239
1987 Guggino SE, Guggino WB, Green N, Sacktor B. Blocking agents of Ca2+-activated K+ channels in cultured medullary thick ascending limb cells. The American Journal of Physiology. 252: C128-37. PMID 2435161 DOI: 10.1152/ajpcell.1987.252.2.C128  0.236
1989 Guggino WB, Guggino SE. Renal anion transport. Kidney International. 36: 385-91. PMID 2687565 DOI: 10.1038/Ki.1989.207  0.235
1990 Guggino WB, Markakis D, Amzel LM. Measurements of volume and shape changes in isolated tubules. Methods in Enzymology. 191: 371-9. PMID 2074767 DOI: 10.1016/0076-6879(90)91024-Z  0.23
2017 Guggino W, Engelhardt J, Yan Z, Cebotaru L. EPS1.2 Transduction of rhesus macaque lung by AAV1 Journal of Cystic Fibrosis. 16: S36. DOI: 10.1016/S1569-1993(17)30275-8  0.227
2018 Yanda M, Wang H, Guggino W, Cebotaru L. EPS3.01 Transduction of rhesus macaque lung following repeat dosing by adeno-associated virus serotype 1 Journal of Cystic Fibrosis. 17: S41. DOI: 10.1016/S1569-1993(18)30246-7  0.225
1995 Schwiebert EM, Gruenert DC, Guggino WB, Stanton BA. G protein G alpha i-2 inhibits outwardly rectifying chloride channels in human airway epithelial cells. The American Journal of Physiology. 269: C451-6. PMID 7544531 DOI: 10.1152/Ajpcell.1995.269.2.C451  0.213
1982 Oberleithner H, Guggino W, Giebisch G. Mechanism of distal tubular chloride transport in Amphiuma kidney. The American Journal of Physiology. 242: F331-9. PMID 7065243 DOI: 10.1152/Ajprenal.1982.242.4.F331  0.208
1986 Guggino WB. Functional heterogeneity in the early distal tubule of the Amphiuma kidney: evidence for two modes of Cl- and K+ transport across the basolateral cell membrane. The American Journal of Physiology. 250: F430-40. PMID 3953823 DOI: 10.1152/ajprenal.1986.250.3.F430  0.206
1983 London R, Cohen B, Guggino WB, Giebisch G. Regulation of intracellular chloride activity during perfusion with hypertonic solutions in the Necturus proximal tubule. The Journal of Membrane Biology. 75: 253-8. PMID 6313931 DOI: 10.1007/Bf01871956  0.204
2000 Hanaoka K, Guggino WB. cAMP regulates cell proliferation and cyst formation in autosomal polycystic kidney disease cells. Journal of the American Society of Nephrology : Jasn. 11: 1179-1187. PMID 10864573 DOI: 10.1681/ASN.V1171179  0.204
1987 Cornejo M, Guggino SE, Guggino WB. Modification of Ca2+-activated K+ channels in cultured medullary thick ascending limb cells by N-bromoacetamide. The Journal of Membrane Biology. 99: 147-55. PMID 2448473 DOI: 10.1007/BF01871234  0.203
2003 Flotte TR, Zeitlin PL, Reynolds TC, Heald AE, Pedersen P, Beck S, Conrad CK, Brass-Ernst L, Humphries M, Sullivan K, Wetzel R, Taylor G, Carter BJ, Guggino WB. Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study. Human Gene Therapy. 14: 1079-88. PMID 12885347 DOI: 10.1089/104303403322124792  0.202
1995 Murray CB, Morales MM, Flotte TR, McGrath-Morrow SA, Guggino WB, Zeitlin PL. CIC-2: a developmentally dependent chloride channel expressed in the fetal lung and downregulated after birth. American Journal of Respiratory Cell and Molecular Biology. 12: 597-604. PMID 7766424 DOI: 10.1165/ajrcmb.12.6.7766424  0.202
1993 Eismann E, Bönigk W, Kaupp B, Macdonald RL, Angelotti TP, Paulmichl M, Gschwentner M, Wöll E, Schmarda A, Ritter M, Kanin G, Ellemunter H, Waitz W, Deetjen P, Carroll TP, ... ... Guggino WB, et al. Contents, Vol. 3, 1993 Cellular Physiology and Biochemistry. 3. DOI: 10.1159/000154687  0.192
1992 Palfrey C, O’Donnell ME, Hwang T, Egan ME, Guggino WB, Hurst AM, Duplain M, Lapointe J, White S, Boulpaep E, Giebisch G, Nonnotte G, Truchot J-, Bayad J, Sabolovic N, et al. Contents, Vol. 2, 1992 Cellular Physiology and Biochemistry. 2. DOI: 10.1159/000154651  0.192
1991 Hollunder-Reese F, Mohrmann M, Bleich M, Greger R, Lu L, Markakis D, Guggino WB, Granitzer M, Lyoussi B, Nagel W, Crabbé J, Leipziger J, Nitschke R, Schäfer C, Westphale H, et al. Contents, Vol. 1, 1991 Cellular Physiology and Biochemistry. 1. DOI: 10.1159/000154610  0.192
1998 Taylor AL, Kudlow BA, Marrs KL, Gruenert DC, Guggino WB, Schwiebert EM. Bioluminescence detection of ATP release mechanisms in epithelia. American Journal of Physiology. Cell Physiology. 275: C1391-C1406. PMID 29585383 DOI: 10.1152/ajpcell.1998.275.5.C1391  0.192
1983 Guggino WB, London R, Boulpaep EL, Giebisch G. Chloride transport across the basolateral cell membrane of the Necturus proximal tubule: Dependence on bicarbonate and sodium The Journal of Membrane Biology. 71: 227-240. PMID 6302263 DOI: 10.1007/Bf01875464  0.19
1998 Woo JS, Inoue CN, Hanaoka K, Schwiebert EM, Guggino SE, Guggino WB. Adenylyl cyclase is involved in desensitization and recovery of ATP-stimulated Clsecretion in MDCK cells. American Journal of Physiology. Cell Physiology. 274: C371-C378. PMID 29590930 DOI: 10.1152/ajpcell.1998.274.2.C371  0.187
2023 Yanda MK, Zeidan A, Ciobanu C, Izzi J, Guggino W, Cebotaru L. Transduction of ferret surface and basal cells of airways, lung, liver and pancreas via intratracheal or intravenous delivery of AA1 or 6. Human Gene Therapy. PMID 37650819 DOI: 10.1089/hum.2023.095  0.186
1982 Guggino WB, Boulpaep EL, Giebisch G. Electrical properties of chloride transport across the Necturus proximal tubule The Journal of Membrane Biology. 65: 185-196. PMID 7062339 DOI: 10.1007/Bf01869962  0.182
1999 Beck SE, Jones LA, Chesnut K, Walsh SM, Reynolds TC, Carter BJ, Askin FB, Flotte TR, Guggino WB. Repeated Delivery of Adeno-Associated Virus Vectors to the Rabbit Airway Journal of Virology. 73: 9446-9455. DOI: 10.1128/jvi.73.11.9446-9455.1999  0.181
2021 Yanda MK, Tomar V, Cole R, Guggino WB, Cebotaru L. The Mitochondrial Ca import complex is altered in ADPKD. Cell Calcium. 101: 102501. PMID 34823104 DOI: 10.1016/j.ceca.2021.102501  0.179
2019 Cebotaru L, Guggino W. P025 The PDZ-containing domain protein, CAL links CFTR to the regulation of inflammation Journal of Cystic Fibrosis. 18: S64. DOI: 10.1016/S1569-1993(19)30320-0  0.178
1984 Matsumura Y, Cohen B, Guggino WB, Giebisch G. Regulation of the basolateral potassium conductance of the Necturus proximal tubule. The Journal of Membrane Biology. 79: 153-61. PMID 6086932 DOI: 10.1007/Bf01872119  0.176
1989 Cornejo M, Guggino SE, Sastre A, Guggino WB. Isomeric yohimbine alkaloids block calcium-activated K+ channels in medullary thick ascending limb cells of rabbit kidney. The Journal of Membrane Biology. 107: 25-33. PMID 2921768 DOI: 10.1007/BF01871080  0.175
1993 Eismann E, Bönigk W, Kaupp B, Macdonald RL, Angelotti TP, Paulmichl M, Gschwentner M, Wöll E, Schmarda A, Ritter M, Kanin G, Ellemunter H, Waitz W, Deetjen P, Carroll TP, ... ... Guggino WB, et al. Subject Index, Vol. 3, 1993 Cellular Physiology and Biochemistry. 3: 401-402. DOI: 10.1159/000154702  0.175
1991 Hollunder-Reese F, Mohrmann M, Bleich M, Greger R, Lu L, Markakis D, Guggino WB, Granitzer M, Lyoussi B, Nagel W, Crabbé J, Leipziger J, Nitschke R, Schäfer C, Westphale H, et al. Subject Index, Vol. 1, 1991 Cellular Physiology and Biochemistry. 1: 306-307. DOI: 10.1159/000154619  0.175
2008 Wright J, Morales MM, Sousa-Menzes J, Ornellas D, Sipes J, Cui Y, Cui I, Hulamm P, Cebotaru V, Cebotaru L, Guggino WB, Guggino SE. Transcriptional adaptation to Clcn5 knockout in proximal tubules of mouse kidney. Physiological Genomics. 33: 341-54. PMID 18349385 DOI: 10.1152/physiolgenomics.00024.2008  0.171
2022 Yanda MK, Tomar V, Cebotaru CV, Guggino WB, Cebotaru L. Short-Term Steroid Treatment of Rhesus Macaque Increases Transduction. Human Gene Therapy. PMID 34806411 DOI: 10.1089/hum.2021.239  0.16
2010 Cebotaru L, Guggino W. CFTR missing the last four transmembrane segments and nucleotide binding domain 2 resides in the ER but escapes the cell's quality control mechanism Journal of Cystic Fibrosis. 9: S14. DOI: 10.1016/S1569-1993(10)60053-7  0.156
1990 Hwang TC, Guggino SE, Guggino WB. Direct modulation of secretory chloride channels by arachidonic and other cis unsaturated fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 87: 5706-9. PMID 1696009 DOI: 10.1073/pnas.87.15.5706  0.145
1984 Matsumura Y, Cohen B, Guggino WB, Giebisch G. Electrical effects of potassium and bicarbonate on proximal tubule cells of Necturus. The Journal of Membrane Biology. 79: 145-52. PMID 6748054 DOI: 10.1007/Bf01872118  0.141
1980 Guggino WB. Salt balance in embryos of Fundulus heteroclitus and F. bermudae adapted to seawater. The American Journal of Physiology. 238: R42-9. PMID 7356047 DOI: 10.1152/ajpregu.1980.238.1.R42  0.14
2021 Peruchetti DB, Barahuna-Filho PFR, Silva-Aguiar RP, Abreu TP, Takiya CM, Cheng J, Pinheiro AAS, Cebotaru L, Guggino WB, Caruso-Neves C. Megalin-mediated albumin endocytosis in renal proximal tubules is involved in the antiproteinuric effect of angiotensin II type 1 receptor blocker in a subclinical acute kidney injury animal model. Biochimica Et Biophysica Acta. General Subjects. 1865: 129950. PMID 34144121 DOI: 10.1016/j.bbagen.2021.129950  0.139
2010 Balch WE, Braakman I, Brodsky J, Frizzell R, Guggino W, Lukacs GL, Penland C, Pollard H, Skach W, Sorscher E, Thomas P. Folding Biology of Cystic Fibrosis: A Consortium-Based Approach to Disease Protein Misfolding Diseases: Current and Emerging Principles and Therapies. 425-452. DOI: 10.1002/9780470572702.ch19  0.12
1983 Oberleithner H, Guggino W, Giebisch G. The effect of furosemide on luminal sodium, chloride and potassium transport in the early distal tubule of Amphiuma kidney. Effects of potassium adaptation. Pflugers Archiv : European Journal of Physiology. 396: 27-33. PMID 6835805 DOI: 10.1007/Bf00584694  0.12
1982 Guggino WB, Windhager EE, Boulpaep EL, Giebisch G. Cellular and paracellular resistances of the Necturus proximal tubule The Journal of Membrane Biology. 67: 143-154. PMID 7097759 DOI: 10.1007/Bf01868657  0.114
1997 Flotte TR, Zeitlin PL, Daifuku R, Afione S, Schwiebert E, Allen S, Beck S, Reynolds T, Wagner M, Brass-Ernst L, Taylor G, Wetzel R, Sullivan K, Friborg S, Humphries M, ... ... Guggino WB, et al. A Phase I Study of AAV-CFTR Administration in Adult Cystic Fibrosis Patients 1794 Pediatric Research. 41: 301-301. DOI: 10.1203/00006450-199704001-01813  0.11
1986 Oberleithner H, Guggino W, Giebisch G. Resistance properties of the diluting segment of Amphiuma kidney: influence of potassium adaptation. The Journal of Membrane Biology. 88: 139-47. PMID 4093957 DOI: 10.1007/Bf01868428  0.107
2002 Wagner JA, Nepomuceno IB, Messner AH, Moran ML, Batson EP, Dimiceli S, Brown BW, Desch JK, Norbash AM, Conrad CK, Guggino WB, Flotte TR, Wine JJ, Carter BJ, Reynolds TC, et al. A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies. Human Gene Therapy. 13: 1349-59. PMID 12162817 DOI: 10.1089/104303402760128577  0.104
1983 Oberleithner H, Guggino W, Giebisch G. Potassium transport in the early distal tubule of Amphiuma kidney. Effects of potassium adaptation. Pflugers Archiv : European Journal of Physiology. 396: 185-91. PMID 6302633 DOI: 10.1007/Bf00587854  0.087
2008 Pollard HB, Eidelman O, Srivastava M, Joswik C, Rothwell S, Mueller GP, Jacobowitz DM, Guggino WB, Wright J, Zeitlin PL, Paweletz CP. Antibody and Reverse Capture Protein Microarrays for Clinical Proteomics Clinical Proteomics: From Diagnosis to Therapy. 549-569. DOI: 10.1002/9783527622153.ch30  0.074
1997 Byrne BJ, Pauly DF, Zhang G, Chen X, Guggino WB, Kurtzman GJ, Kessler PD. Gene Replacement in Acid Maltase Deficiency Using DNA Viral Vectors. • 98 Pediatric Research. 41: 19-19. DOI: 10.1203/00006450-199704001-00119  0.069
1996 Afione SA, Conrad CK, Kearns WG, Chunduru S, Adams R, Reynolds TC, Guggino WB, Cutting GR, Carter BJ, Flotte TR. In vivo model of adeno-associated virus vector persistence and rescue. Journal of Virology. 70: 3235-3241. DOI: 10.1128/jvi.70.5.3235-3241.1996  0.063
2010 Eidelman O, Jozwik C, Huang W, Srivastava M, Rothwell SW, Jacobowitz DM, Ji X, Zhang X, Guggino W, Wright J, Kiefer J, Olsen C, Adimi N, Mueller GP, Pollard HB. Gender dependence for a subset of the low-abundance signaling proteome in human platelets. Human Genomics and Proteomics : Hgp. 2010: 164906. PMID 20981232 DOI: 10.4061/2010/164906  0.061
1980 Guggino WB. Water balance in embryos of Fundulus heteroclitus and F. bermudae in seawater. The American Journal of Physiology. 238: R36-41. PMID 7356046 DOI: 10.1152/ajpregu.1980.238.1.R36  0.056
1997 Agre P, Lee MD, Devidas S, Guggino WB. Aquaporins and ion conductance. Science (New York, N.Y.). 275: 1490; author reply 1. PMID 9045617 DOI: 10.1126/science.275.5305.1490  0.04
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