| Year |
Citation |
Score |
| 2018 |
Valley HC, Bukis KM, Bell A, Cheng Y, Wong E, Jordan NJ, Allaire NE, Sivachenko A, Liang F, Bihler H, Thomas PJ, Mahiou J, Mense M. Isogenic cell models of cystic fibrosis-causing variants in natively expressing pulmonary epithelial cells. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 30563749 DOI: 10.1016/J.Jcf.2018.12.001 |
0.311 |
|
| 2018 |
Clancy JP, Cotton CU, Donaldson SH, Solomon GM, VanDevanter DR, Boyle MP, Gentzsch M, Nick JA, Illek B, Wallenburg JC, Sorscher EJ, Amaral MD, Beekman JM, Naren AP, Bridges RJ, ... Thomas PJ, et al. CFTR modulator theratyping: Current status, gaps and future directions. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 29934203 DOI: 10.1016/J.Jcf.2018.05.004 |
0.343 |
|
| 2018 |
Pinarbasi ES, Karamyshev AL, Tikhonova EB, Wu IH, Hudson H, Thomas PJ. Pathogenic Signal Sequence Mutations in Progranulin Disrupt SRP Interactions Required for mRNA Stability. Cell Reports. 23: 2844-2851. PMID 29874572 DOI: 10.1016/J.Celrep.2018.05.003 |
0.334 |
|
| 2018 |
Pinarbasi ES, Cağatay T, Fung HYJ, Li YC, Chook YM, Thomas PJ. Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization. Scientific Reports. 8: 7083. PMID 29728608 DOI: 10.1038/S41598-018-25008-4 |
0.338 |
|
| 2018 |
Peters-Hall JR, Coquelin ML, Torres MJ, LaRanger R, Alabi BR, Sho S, Calva-Moreno JF, Thomas PJ, Shay JW. Long-term Culture and Cloning of Primary Human Bronchial Basal Cells that Maintain Multipotent Differentiation Capacity and CFTR Channel Function. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29722564 DOI: 10.1152/Ajplung.00355.2017 |
0.337 |
|
| 2018 |
Seljeset S, Bright DP, Thomas P, Smart TG. Probing GABAreceptors with inhibitory neurosteroids. Neuropharmacology. PMID 29447845 DOI: 10.1016/J.Neuropharm.2018.02.008 |
0.303 |
|
| 2017 |
Hudson RP, Dawson JE, Chong PA, Yang Z, Millen L, Thomas PJ, Brouillette CG, Forman-Kay JD. Direct Binding of the Corrector VX-809 to human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 interface. Molecular Pharmacology. PMID 28546419 DOI: 10.1124/Mol.117.108373 |
0.327 |
|
| 2016 |
Vetter AJ, Karamyshev AL, Patrick AE, Hudson H, Thomas PJ. N-Alpha-Acetyltransferases and Regulation of CFTR Expression. Plos One. 11: e0155430. PMID 27182737 DOI: 10.1371/Journal.Pone.0155430 |
0.374 |
|
| 2015 |
Chua A, Thomas P, Clifton P, Fenech M. Chromosomal DNA damage in APOE ɛ4 carriers and noncarriers does not appear to be different. Environmental and Molecular Mutagenesis. PMID 25820038 DOI: 10.1002/Em.21949 |
0.304 |
|
| 2014 |
Zacchi LF, Wu HC, Bell SL, Millen L, Paton AW, Paton JC, Thomas PJ, Zolkiewski M, Brodsky JL. The BiP molecular chaperone plays multiple roles during the biogenesis of torsinA, an AAA+ ATPase associated with the neurological disease early-onset torsion dystonia. The Journal of Biological Chemistry. 289: 12727-47. PMID 24627482 DOI: 10.1074/Jbc.M113.529123 |
0.357 |
|
| 2014 |
Lee SL, Thomas P, Fenech M. Extracellular amyloid beta 42 causes necrosis, inhibition of nuclear division, and mitotic disruption under both folate deficient and folate replete conditions as measured by the cytokinesis-block micronucleus cytome assay. Environmental and Molecular Mutagenesis. 55: 1-14. PMID 24038346 DOI: 10.1002/Em.21811 |
0.312 |
|
| 2013 |
Bozoky Z, Krzeminski M, Muhandiram R, Birtley JR, Al-Zahrani A, Thomas PJ, Frizzell RA, Ford RC, Forman-Kay JD. Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions. Proceedings of the National Academy of Sciences of the United States of America. 110: E4427-36. PMID 24191035 DOI: 10.1073/Pnas.1315104110 |
0.343 |
|
| 2013 |
Sosnay PR, Siklosi KR, Van Goor F, Kaniecki K, Yu H, Sharma N, Ramalho AS, Amaral MD, Dorfman R, Zielenski J, Masica DL, Karchin R, Millen L, Thomas PJ, Patrinos GP, et al. Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene. Nature Genetics. 45: 1160-7. PMID 23974870 DOI: 10.1038/Ng.2745 |
0.31 |
|
| 2013 |
Fichman M, Schmidt A, Thomas PJ, Senderowitz H. WS4.2 Exploration of the ATP binding site in CFTR-NBD1 for enhanced ligand binding Journal of Cystic Fibrosis. 12. DOI: 10.1016/S1569-1993(13)60020-X |
0.353 |
|
| 2012 |
Patrick AE, Thomas PJ. Development of CFTR Structure. Frontiers in Pharmacology. 3: 162. PMID 22973227 DOI: 10.3389/Fphar.2012.00162 |
0.42 |
|
| 2012 |
Somalinga BR, Day CE, Wei S, Roth MG, Thomas PJ. TDP-43 identified from a genome wide RNAi screen for SOD1 regulators. Plos One. 7: e35818. PMID 22563406 DOI: 10.1371/Journal.Pone.0035818 |
0.316 |
|
| 2012 |
Mendoza JL, Schmidt A, Li Q, Nuvaga E, Barrett T, Bridges RJ, Feranchak AP, Brautigam CA, Thomas PJ. Requirements for efficient correction of ΔF508 CFTR revealed by analyses of evolved sequences. Cell. 148: 164-74. PMID 22265409 DOI: 10.1016/J.Cell.2011.11.023 |
0.615 |
|
| 2012 |
Zhu L, Millen L, Mendoza J, Thomas P. 1.270 A UNIQUE REDOX-SENSING SENSOR-II MOTIF IN TORSINA PLAYS A CRITICAL ROLE IN NUCLEOTIDE AND PARTNER BINDING Parkinsonism & Related Disorders. 18: S64. DOI: 10.1016/S1353-8020(11)70328-5 |
0.489 |
|
| 2011 |
Patrick AE, Karamyshev AL, Millen L, Thomas PJ. Alteration of CFTR transmembrane span integration by disease-causing mutations. Molecular Biology of the Cell. 22: 4461-71. PMID 21998193 DOI: 10.1091/Mbc.E11-05-0396 |
0.356 |
|
| 2011 |
Somalinga BR, Miller GA, Malik HT, Wigley WC, Thomas PJ. A screen to identify cellular modulators of soluble levels of an amyotrophic lateral sclerosis (ALS)-causing mutant SOD1. Journal of Biomolecular Screening. 16: 974-85. PMID 21875953 DOI: 10.1177/1087057111418505 |
0.313 |
|
| 2011 |
Schmidt A, Mendoza JL, Thomas PJ. Biochemical and biophysical approaches to probe CFTR structure. Methods in Molecular Biology (Clifton, N.J.). 741: 365-76. PMID 21594797 DOI: 10.1007/978-1-61779-117-8_24 |
0.633 |
|
| 2011 |
Mendoza JL, Schmidt A, Thomas PJ. Introduction to section IV: biophysical methods to approach CFTR structure. Methods in Molecular Biology (Clifton, N.J.). 741: 321-7. PMID 21594794 DOI: 10.1007/978-1-61779-117-8_21 |
0.589 |
|
| 2011 |
Peters KW, Okiyoneda T, Balch WE, Braakman I, Brodsky JL, Guggino WB, Penland CM, Pollard HB, Sorscher EJ, Skach WR, Thomas PJ, Lukacs GL, Frizzell RA. CFTR Folding Consortium: methods available for studies of CFTR folding and correction. Methods in Molecular Biology (Clifton, N.J.). 742: 335-53. PMID 21547742 DOI: 10.1007/978-1-61779-120-8_20 |
0.368 |
|
| 2011 |
Yang D, Li Q, So I, Huang CL, Ando H, Mizutani A, Seki G, Mikoshiba K, Thomas PJ, Muallem S. IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway. The Journal of Clinical Investigation. 121: 956-65. PMID 21317537 DOI: 10.1172/Jci43475 |
0.306 |
|
| 2011 |
Thomas P, Mendoza JL, Schmidt A, Millen L. Mutations that Disrupt Formation of Functional CFTR Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.2177 |
0.636 |
|
| 2010 |
Hoelen H, Kleizen B, Schmidt A, Richardson J, Charitou P, Thomas PJ, Braakman I. The primary folding defect and rescue of ΔF508 CFTR emerge during translation of the mutant domain. Plos One. 5: e15458. PMID 21152102 DOI: 10.1371/Journal.Pone.0015458 |
0.397 |
|
| 2010 |
Kalid O, Mense M, Fischman S, Shitrit A, Bihler H, Ben-Zeev E, Schutz N, Pedemonte N, Thomas PJ, Bridges RJ, Wetmore DR, Marantz Y, Senderowitz H. Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening. Journal of Computer-Aided Molecular Design. 24: 971-91. PMID 20976528 DOI: 10.1007/S10822-010-9390-0 |
0.342 |
|
| 2010 |
Zhu L, Millen L, Mendoza JL, Thomas PJ. A unique redox-sensing sensor II motif in TorsinA plays a critical role in nucleotide and partner binding. The Journal of Biological Chemistry. 285: 37271-80. PMID 20861018 DOI: 10.1074/Jbc.M110.123471 |
0.601 |
|
| 2010 |
Thibodeau PH, Richardson JM, Wang W, Millen L, Watson J, Mendoza JL, Du K, Fischman S, Senderowitz H, Lukacs GL, Kirk K, Thomas PJ. The cystic fibrosis-causing mutation deltaF508 affects multiple steps in cystic fibrosis transmembrane conductance regulator biogenesis. The Journal of Biological Chemistry. 285: 35825-35. PMID 20667826 DOI: 10.1074/Jbc.M110.131623 |
0.616 |
|
| 2010 |
Lewis KA, Yaeger A, DeMartino GN, Thomas PJ. Accelerated formation of alpha-synuclein oligomers by concerted action of the 20S proteasome and familial Parkinson mutations. Journal of Bioenergetics and Biomembranes. 42: 85-95. PMID 20148295 DOI: 10.1007/S10863-009-9258-Y |
0.312 |
|
| 2010 |
Hutt DM, Herman D, Rodrigues AP, Noel S, Pilewski JM, Matteson J, Hoch B, Kellner W, Kelly JW, Schmidt A, Thomas PJ, Matsumura Y, Skach WR, Gentzsch M, Riordan JR, et al. Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nature Chemical Biology. 6: 25-33. PMID 19966789 DOI: 10.1038/Nchembio.275 |
0.342 |
|
| 2010 |
Kanelis V, Hudson RP, Thibodeau PH, Thomas PJ, Forman-Kay JD. NMR evidence for differential phosphorylation-dependent interactions in WT and DeltaF508 CFTR. The Embo Journal. 29: 263-77. PMID 19927121 DOI: 10.1038/Emboj.2009.329 |
0.382 |
|
| 2008 |
Zhu L, Wrabl JO, Hayashi AP, Rose LS, Thomas PJ. The torsin-family AAA+ protein OOC-5 contains a critical disulfide adjacent to Sensor-II that couples redox state to nucleotide binding. Molecular Biology of the Cell. 19: 3599-612. PMID 18550799 DOI: 10.1091/Mbc.E08-01-0015 |
0.331 |
|
| 2008 |
Dorwart MR, Shcheynikov N, Baker JM, Forman-Kay JD, Muallem S, Thomas PJ. Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3. The Journal of Biological Chemistry. 283: 8711-22. PMID 18216024 DOI: 10.1074/Jbc.M704328200 |
0.389 |
|
| 2008 |
Pissarra LS, Farinha CM, Xu Z, Schmidt A, Thibodeau PH, Cai Z, Thomas PJ, Sheppard DN, Amaral MD. Solubilizing mutations used to crystallize one CFTR domain attenuate the trafficking and channel defects caused by the major cystic fibrosis mutation. Chemistry & Biology. 15: 62-9. PMID 18215773 DOI: 10.1016/J.Chembiol.2007.11.012 |
0.386 |
|
| 2007 |
Mendoza JL, Thomas PJ. Building an understanding of cystic fibrosis on the foundation of ABC transporter structures. Journal of Bioenergetics and Biomembranes. 39: 499-505. PMID 18080175 DOI: 10.1007/S10863-007-9117-7 |
0.606 |
|
| 2007 |
Baker JM, Hudson RP, Kanelis V, Choy WY, Thibodeau PH, Thomas PJ, Forman-Kay JD. CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices. Nature Structural & Molecular Biology. 14: 738-45. PMID 17660831 DOI: 10.1038/Nsmb1278 |
0.311 |
|
| 2007 |
Szebenyi G, Wigley WC, Hall B, Didier A, Yu M, Thomas P, Krämer H. Hook2 contributes to aggresome formation. Bmc Cell Biology. 8: 19. PMID 17540036 DOI: 10.1186/1471-2121-8-19 |
0.346 |
|
| 2006 |
Shcheynikov N, Ko SB, Zeng W, Choi JY, Dorwart MR, Thomas PJ, Muallem S. Regulatory interaction between CFTR and the SLC26 transporters. Novartis Foundation Symposium. 273: 177-86; discussion 1. PMID 17120768 DOI: 10.1002/0470029579.Ch12 |
0.349 |
|
| 2006 |
Wang Y, Soyombo AA, Shcheynikov N, Zeng W, Dorwart M, Marino CR, Thomas PJ, Muallem S. Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO3- secretion: relevance to cystic fibrosis. The Embo Journal. 25: 5049-57. PMID 17053783 DOI: 10.1038/Sj.Emboj.7601387 |
0.33 |
|
| 2006 |
Liu CW, Li X, Thompson D, Wooding K, Chang TL, Tang Z, Yu H, Thomas PJ, DeMartino GN. ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome. Molecular Cell. 24: 39-50. PMID 17018291 DOI: 10.1016/J.Molcel.2006.08.025 |
0.328 |
|
| 2005 |
Moody JE, Thomas PJ. Nucleotide binding domain interactions during the mechanochemical reaction cycle of ATP-binding cassette transporters. Journal of Bioenergetics and Biomembranes. 37: 475-9. PMID 16691486 DOI: 10.1007/S10863-005-9494-8 |
0.335 |
|
| 2005 |
Liu CW, Giasson BI, Lewis KA, Lee VM, Demartino GN, Thomas PJ. A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease. The Journal of Biological Chemistry. 280: 22670-8. PMID 15840579 DOI: 10.1074/Jbc.M501508200 |
0.306 |
|
| 2005 |
Thibodeau PH, Brautigam CA, Machius M, Thomas PJ. Side chain and backbone contributions of Phe508 to CFTR folding. Nature Structural & Molecular Biology. 12: 10-6. PMID 15619636 DOI: 10.1038/Nsmb881 |
0.407 |
|
| 2004 |
Dorwart M, Thibodeau P, Thomas P. Cystic fibrosis: recent structural insights. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 3: 91-4. PMID 15463935 DOI: 10.1016/J.Jcf.2004.05.020 |
0.399 |
|
| 2004 |
Lee RJ, Liu CW, Harty C, McCracken AA, Latterich M, Römisch K, DeMartino GN, Thomas PJ, Brodsky JL. Uncoupling retro-translocation and degradation in the ER-associated degradation of a soluble protein. The Embo Journal. 23: 2206-15. PMID 15152188 DOI: 10.1038/Sj.Emboj.7600232 |
0.31 |
|
| 2004 |
Ko SB, Zeng W, Dorwart MR, Luo X, Kim KH, Millen L, Goto H, Naruse S, Soyombo A, Thomas PJ, Muallem S. Gating of CFTR by the STAS domain of SLC26 transporters. Nature Cell Biology. 6: 343-50. PMID 15048129 DOI: 10.1038/Ncb1115 |
0.392 |
|
| 2004 |
Lewis HA, Buchanan SG, Burley SK, Conners K, Dickey M, Dorwart M, Fowler R, Gao X, Guggino WB, Hendrickson WA, Hunt JF, Kearins MC, Lorimer D, Maloney PC, Post KW, ... ... Thomas PJ, et al. Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator. The Embo Journal. 23: 282-93. PMID 14685259 DOI: 10.1038/Sj.Emboj.7600040 |
0.393 |
|
| 2003 |
Lee SF, Shah S, Yu C, Wigley WC, Li H, Lim M, Pedersen K, Han W, Thomas P, Lundkvist J, Hao YH, Yu G. A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gamma-secretase complex. The Journal of Biological Chemistry. 279: 4144-52. PMID 14627705 DOI: 10.1074/Jbc.M309745200 |
0.338 |
|
| 2003 |
Zhang XM, Wang XT, Yue H, Leung SW, Thibodeau PH, Thomas PJ, Guggino SE. Organic solutes rescue the functional defect in delta F508 cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 278: 51232-42. PMID 14532265 DOI: 10.1074/Jbc.M309076200 |
0.367 |
|
| 2003 |
Liu CW, Corboy MJ, DeMartino GN, Thomas PJ. Endoproteolytic activity of the proteasome. Science (New York, N.Y.). 299: 408-11. PMID 12481023 DOI: 10.1126/Science.1079293 |
0.304 |
|
| 2002 |
Ko SB, Shcheynikov N, Choi JY, Luo X, Ishibashi K, Thomas PJ, Kim JY, Kim KH, Lee MG, Naruse S, Muallem S. A molecular mechanism for aberrant CFTR-dependent HCO(3)(-) transport in cystic fibrosis. The Embo Journal. 21: 5662-72. PMID 12411484 DOI: 10.1093/Emboj/Cdf580 |
0.329 |
|
| 2002 |
Park M, Ko SB, Choi JY, Muallem G, Thomas PJ, Pushkin A, Lee MS, Kim JY, Lee MG, Muallem S, Kurtz I. The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3. The Journal of Biological Chemistry. 277: 50503-9. PMID 12403779 DOI: 10.1074/Jbc.M201862200 |
0.363 |
|
| 2002 |
Smith PC, Karpowich N, Millen L, Moody JE, Rosen J, Thomas PJ, Hunt JF. ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Molecular Cell. 10: 139-49. PMID 12150914 DOI: 10.1016/S1097-2765(02)00576-2 |
0.338 |
|
| 2002 |
Liu CW, Millen L, Roman TB, Xiong H, Gilbert HF, Noiva R, DeMartino GN, Thomas PJ. Conformational remodeling of proteasomal substrates by PA700, the 19 S regulatory complex of the 26 S proteasome. The Journal of Biological Chemistry. 277: 26815-20. PMID 12011044 DOI: 10.1074/Jbc.M201782200 |
0.306 |
|
| 2002 |
Moody JE, Millen L, Binns D, Hunt JF, Thomas PJ. Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters. The Journal of Biological Chemistry. 277: 21111-4. PMID 11964392 DOI: 10.1074/Jbc.C200228200 |
0.34 |
|
| 2002 |
Wigley WC, Corboy MJ, Cutler TD, Thibodeau PH, Oldan J, Lee MG, Rizo J, Hunt JF, Thomas PJ. A protein sequence that can encode native structure by disfavoring alternate conformations. Nature Structural Biology. 9: 381-8. PMID 11938353 DOI: 10.1038/Nsb784 |
0.323 |
|
| 2002 |
Stidham RD, Wigley WC, Thomas PJ. In vitro CFTR folding assays. Methods in Molecular Medicine. 70: 311-22. PMID 11917534 DOI: 10.1385/1-59259-187-6:311 |
0.306 |
|
| 2002 |
Berger AL, Ikuma M, Hunt JF, Thomas PJ, Welsh MJ. Mutations that change the position of the putative gamma-phosphate linker in the nucleotide binding domains of CFTR alter channel gating. The Journal of Biological Chemistry. 277: 2125-31. PMID 11788611 DOI: 10.1074/Jbc.M109539200 |
0.359 |
|
| 2001 |
Thomas PJ, Hunt JF. A snapshot of Nature's favorite pump. Nature Structural Biology. 8: 920-3. PMID 11685233 DOI: 10.1038/Nsb1101-920 |
0.338 |
|
| 2001 |
Karpowich N, Martsinkevich O, Millen L, Yuan YR, Dai PL, MacVey K, Thomas PJ, Hunt JF. Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter. Structure (London, England : 1993). 9: 571-86. PMID 11470432 DOI: 10.1016/S0969-2126(01)00617-7 |
0.337 |
|
| 2001 |
Yuan YR, Blecker S, Martsinkevich O, Millen L, Thomas PJ, Hunt JF. The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter. The Journal of Biological Chemistry. 276: 32313-21. PMID 11402022 DOI: 10.1074/Jbc.M100758200 |
0.334 |
|
| 2001 |
Choi JY, Muallem D, Kiselyov K, Lee MG, Thomas PJ, Muallem S. Aberrant CFTR-dependent HCO3- transport in mutations associated with cystic fibrosis. Nature. 410: 94-7. PMID 11242048 DOI: 10.1038/35065099 |
0.378 |
|
| 2000 |
Strickland E, Hakala K, Thomas PJ, DeMartino GN. Recognition of misfolding proteins by PA700, the regulatory subcomplex of the 26 S proteasome. The Journal of Biological Chemistry. 275: 5565-72. PMID 10681537 DOI: 10.1074/Jbc.275.8.5565 |
0.323 |
|
| 2000 |
Fabunmi RP, Wigley WC, Thomas PJ, DeMartino GN. Activity and regulation of the centrosome-associated proteasome. The Journal of Biological Chemistry. 275: 409-13. PMID 10617632 DOI: 10.1074/Jbc.275.1.409 |
0.323 |
|
| 1999 |
Harvey RJ, Thomas P, James CH, Wilderspin A, Smart TG. Identification of an inhibitory Zn2+ binding site on the human glycine receptor alpha1 subunit. The Journal of Physiology. 520: 53-64. PMID 10517800 DOI: 10.1111/J.1469-7793.1999.00053.X |
0.315 |
|
| 1999 |
Lee MG, Choi JY, Luo X, Strickland E, Thomas PJ, Muallem S. Cystic fibrosis transmembrane conductance regulator regulates luminal Cl-/HCO3- exchange in mouse submandibular and pancreatic ducts. The Journal of Biological Chemistry. 274: 14670-7. PMID 10329661 DOI: 10.1074/Jbc.274.21.14670 |
0.325 |
|
| 1999 |
Wigley WC, Fabunmi RP, Lee MG, Marino CR, Muallem S, DeMartino GN, Thomas PJ. Dynamic association of proteasomal machinery with the centrosome. The Journal of Cell Biology. 145: 481-90. PMID 10225950 DOI: 10.1083/Jcb.145.3.481 |
0.335 |
|
| 1999 |
Lee MG, Wigley WC, Zeng W, Noel LE, Marino CR, Thomas PJ, Muallem S. Regulation of Cl-/ HCO3- exchange by cystic fibrosis transmembrane conductance regulator expressed in NIH 3T3 and HEK 293 cells. The Journal of Biological Chemistry. 274: 3414-21. PMID 9920885 DOI: 10.1074/Jbc.274.6.3414 |
0.364 |
|
| 1997 |
Qu BH, Strickland E, Thomas PJ. Cystic fibrosis: a disease of altered protein folding. Journal of Bioenergetics and Biomembranes. 29: 483-90. PMID 9511933 DOI: 10.1023/A:1022439108101 |
0.431 |
|
| 1997 |
Strickland E, Qu BH, Millen L, Thomas PJ. The molecular chaperone Hsc70 assists the in vitro folding of the N-terminal nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 272: 25421-4. PMID 9325249 DOI: 10.1074/Jbc.272.41.25421 |
0.384 |
|
| 1997 |
Zeng W, Lee MG, Yan M, Diaz J, Benjamin I, Marino CR, Kopito R, Freedman S, Cotton C, Muallem S, Thomas P. Immuno and functional characterization of CFTR in submandibular and pancreatic acinar and duct cells. The American Journal of Physiology. 273: C442-55. PMID 9277342 DOI: 10.1152/Ajpcell.1997.273.2.C442 |
0.359 |
|
| 1997 |
Qu BH, Strickland EH, Thomas PJ. Localization and suppression of a kinetic defect in cystic fibrosis transmembrane conductance regulator folding. The Journal of Biological Chemistry. 272: 15739-44. PMID 9188468 DOI: 10.1074/Jbc.272.25.15739 |
0.398 |
|
| 1996 |
Qu BH, Thomas PJ. Alteration of the cystic fibrosis transmembrane conductance regulator folding pathway. The Journal of Biological Chemistry. 271: 7261-4. PMID 8631737 DOI: 10.1074/Jbc.271.13.7261 |
0.422 |
|
| 1995 |
Thomas PJ, Qu BH, Pedersen PL. Defective protein folding as a basis of human disease. Trends in Biochemical Sciences. 20: 456-9. PMID 8578588 DOI: 10.1016/S0968-0004(00)89100-8 |
0.357 |
|
| 1993 |
Thomas PJ, Pedersen PL. Effects of the delta F508 mutation on the structure, function, and folding of the first nucleotide-binding domain of CFTR. Journal of Bioenergetics and Biomembranes. 25: 11-9. PMID 7680027 DOI: 10.1007/Bf00768063 |
0.394 |
|
| 1992 |
Thomas PJ, Ko YH, Pedersen PL. Altered protein folding may be the molecular basis of most cases of cystic fibrosis. Febs Letters. 312: 7-9. PMID 1385213 DOI: 10.1016/0014-5793(92)81399-7 |
0.385 |
|
| 1992 |
Thomas PJ, Bianchet MA, Garboczi DN, Hullihen J, Amzel ML, Pedersen PL. ATP synthase: structure-function relationships Biochimica Et Biophysica Acta. 1101: 228-231. DOI: 10.1016/S0005-2728(05)80027-1 |
0.312 |
|
| 1991 |
Thomas PJ, Shenbagamurthi P, Ysern X, Pedersen PL. Cystic fibrosis transmembrane conductance regulator: nucleotide binding to a synthetic peptide. Science (New York, N.Y.). 251: 555-7. PMID 1703660 DOI: 10.1126/Science.1703660 |
0.331 |
|
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