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Yuh Min Chook, Ph.D - Publications

Affiliations: 
Pharmacology and Biophysics University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
Nuclear Transport
Website:
http://www4.utsouthwestern.edu/chooklab/

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Springhower CE, Rosen MK, Chook YM. Karyopherins and condensates. Current Opinion in Cell Biology. 64: 112-123. PMID 32474299 DOI: 10.1016/j.ceb.2020.04.003  1
2019 Lee Y, Baumhardt JM, Pei J, Chook YM, Grishin NV. pCRM1exportome: database of predicted CRM1-dependent Nuclear Export Signal (NES) motifs in cancer-related genes. Bioinformatics (Oxford, England). PMID 31504173 DOI: 10.1093/bioinformatics/btz657  1
2019 Lee Y, Pei J, Baumhardt JM, Chook YM, Grishin NV. Structural prerequisites for CRM1-dependent nuclear export signaling peptides: accessibility, adapting conformation, and the stability at the binding site. Scientific Reports. 9: 6627. PMID 31036839 DOI: 10.1038/s41598-019-43004-0  1
2018 Zhang K, Shang G, Padavannil A, Wang J, Sakthivel R, Chen X, Kim M, Thompson MG, García-Sastre A, Lynch KW, Chen ZJ, Chook YM, Fontoura BMA. Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression. Proceedings of the National Academy of Sciences of the United States of America. PMID 30538201 DOI: 10.1073/pnas.1818012115  1
2018 Fu SC, Fung HYJ, Cağatay T, Baumhardt J, Chook YM. Correlation of CRM1-NES affinity with nuclear export activity. Molecular Biology of the Cell. mbcE18020096. PMID 29927350 DOI: 10.1091/mbc.E18-02-0096  1
2018 Pinarbasi ES, Cağatay T, Fung HYJ, Li YC, Chook YM, Thomas PJ. Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization. Scientific Reports. 8: 7083. PMID 29728608 DOI: 10.1038/s41598-018-25008-4  1
2018 Yoshizawa T, Ali R, Jiou J, Fung HYJ, Burke KA, Kim SJ, Lin Y, Peeples WB, Saltzberg D, Soniat M, Baumhardt JM, Oldenbourg R, Sali A, Fawzi NL, Rosen MK, ... Chook YM, et al. Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell. 173: 693-705.e22. PMID 29677513 DOI: 10.1016/j.cell.2018.03.003  1
2018 Guo L, Kim HJ, Wang H, Monaghan J, Freyermuth F, Sung JC, O'Donovan K, Fare CM, Diaz Z, Singh N, Zhang ZC, Coughlin M, Sweeny EA, DeSantis ME, Jackrel ME, ... ... Chook YM, et al. Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains. Cell. 173: 677-692.e20. PMID 29677512 DOI: 10.1016/j.cell.2018.03.002  1
2018 Chook YM, Fontoura BMA, Rout MP. Günter Blobel 1936-2018. Nature Structural & Molecular Biology. PMID 29610492 DOI: 10.1038/s41594-018-0053-5  1
2017 Fung HY, Fu SC, Chook YM. Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife. 6. PMID 28282025 DOI: 10.7554/eLife.23961  1
2016 Soniat M, Chook YM. Karyopherin-β2 Recognition of a PY-NLS Variant that Lacks the Proline-Tyrosine Motif. Structure (London, England : 1993). PMID 27618664 DOI: 10.1016/j.str.2016.07.018  1
2016 Soniat M, Cağatay T, Chook YM. Recognition elements in the histone H3 and H4 tails for seven different Importins. The Journal of Biological Chemistry. PMID 27528606 DOI: 10.1074/jbc.M116.730218  1
2016 Hing ZA, Fung HY, Ranganathan P, Mitchell S, El-Gamal D, Woyach JA, Williams K, Goettl VM, Smith J, Yu X, Meng X, Sun Q, Cagatay T, Lehman AM, Lucas DM, ... ... Chook YM, et al. Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies. Leukemia. PMID 27323910 DOI: 10.1038/leu.2016.136  1
2016 Volpon L, Culjkovic-Kraljacic B, Osborne MJ, Ramteke A, Sun Q, Niesman A, Chook YM, Borden KL. Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114554 DOI: 10.1073/pnas.1524291113  1
2015 Fung HY, Fu SC, Brautigam CA, Chook YM. Structural determinants of nuclear export signal orientation in binding to exportin CRM1. Elife. 4. PMID 26349033 DOI: 10.7554/eLife.10034  1
2015 Soniat M, Chook YM. Nuclear localization signals for four distinct karyopherin-β nuclear import systems. The Biochemical Journal. 468: 353-62. PMID 26173234 DOI: 10.1042/BJ20150368  1
2015 Haines JD, Herbin O, de la Hera B, Vidaurre OG, Moy GA, Sun Q, Fung HY, Albrecht S, Alexandropoulos K, McCauley D, Chook YM, Kuhlmann T, Kidd GJ, Shacham S, Casaccia P. Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Nature Neuroscience. 18: 511-20. PMID 25706475 DOI: 10.1038/nn.3953  1
2015 Xu D, Marquis K, Pei J, Fu SC, Ca?atay T, Grishin NV, Chook YM. LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins. Bioinformatics (Oxford, England). 31: 1357-65. PMID 25515756 DOI: 10.1093/bioinformatics/btu826  1
2015 Soniat M, Chook YM. Nuclear localization signals for four distinct Karyopherin-β nuclear import systems Biochemical Journal. 468: 353-362. DOI: 10.1042/BJ20150368  1
2014 Fung HY, Chook YM. Atomic basis of CRM1-cargo recognition, release and inhibition. Seminars in Cancer Biology. 27: 52-61. PMID 24631835 DOI: 10.1016/j.semcancer.2014.03.002  1
2014 Bernis C, Swift-Taylor B, Nord M, Carmona S, Chook YM, Forbes DJ. Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration. Molecular Biology of the Cell. 25: 992-1009. PMID 24478460 DOI: 10.1091/mbc.E13-08-0506  1
2013 Soniat M, Sampathkumar P, Collett G, Gizzi AS, Banu RN, Bhosle RC, Chamala S, Chowdhury S, Fiser A, Glenn AS, Hammonds J, Hillerich B, Khafizov K, Love JD, Matikainen B, ... ... Chook YM, et al. Crystal structure of human Karyopherin β2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2. Journal of Structural and Functional Genomics. 14: 31-5. PMID 23535894 DOI: 10.1007/s10969-013-9150-1  1
2013 Sun Q, Carrasco YP, Hu Y, Guo X, Mirzaei H, Macmillan J, Chook YM. Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proceedings of the National Academy of Sciences of the United States of America. 110: 1303-8. PMID 23297231 DOI: 10.1073/pnas.1217203110  1
2013 Etchin J, Sun Q, Kentsis A, Farmer A, Zhang ZC, Sanda T, Mansour MR, Barcelo C, McCauley D, Kauffman M, Shacham S, Christie AL, Kung AL, Rodig SJ, Chook YM, et al. Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells. Leukemia. 27: 66-74. PMID 22847027 DOI: 10.1038/leu.2012.219  1
2012 Lapalombella R, Sun Q, Williams K, Tangeman L, Jha S, Zhong Y, Goettl V, Mahoney E, Berglund C, Gupta S, Farmer A, Mani R, Johnson AJ, Lucas D, Mo X, ... ... Chook YM, et al. Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood. 120: 4621-34. PMID 23034282 DOI: 10.1182/blood-2012-05-429506  1
2012 Xu D, Farmer A, Collett G, Grishin NV, Chook YM. Sequence and structural analyses of nuclear export signals in the NESdb database. Molecular Biology of the Cell. 23: 3677-93. PMID 22833565 DOI: 10.1091/mbc.E12-01-0046  1
2012 Xu D, Grishin NV, Chook YM. NESdb: a database of NES-containing CRM1 cargoes. Molecular Biology of the Cell. 23: 3673-6. PMID 22833564 DOI: 10.1091/mbc.E12-01-0045  1
2012 Zhang ZC, Chook YM. Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS). Proceedings of the National Academy of Sciences of the United States of America. 109: 12017-21. PMID 22778397 DOI: 10.1073/pnas.1207247109  1
2011 Zhang ZC, Satterly N, Fontoura BM, Chook YM. Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1. Molecular Biology of the Cell. 22: 4657-68. PMID 21965294 DOI: 10.1091/mbc.E11-03-0222  1
2011 Ge Q, Nakagawa T, Wynn RM, Chook YM, Miller BC, Uyeda K. Importin-alpha protein binding to a nuclear localization signal of carbohydrate response element-binding protein (ChREBP). The Journal of Biological Chemistry. 286: 28119-27. PMID 21665952 DOI: 10.1074/jbc.M111.237016  1
2011 Chook YM, Süel KE. Nuclear import by karyopherin-βs: recognition and inhibition. Biochimica Et Biophysica Acta. 1813: 1593-606. PMID 21029754 DOI: 10.1016/j.bbamcr.2010.10.014  1
2010 Xu D, Farmer A, Chook YM. Recognition of nuclear targeting signals by Karyopherin-β proteins. Current Opinion in Structural Biology. 20: 782-90. PMID 20951026 DOI: 10.1016/j.sbi.2010.09.008  1
2009 Süel KE, Chook YM. Kap104p imports the PY-NLS-containing transcription factor Tfg2p into the nucleus. The Journal of Biological Chemistry. 284: 15416-24. PMID 19366694 DOI: 10.1074/jbc.M809384200  1
2009 Dong X, Biswas A, Chook YM. Structural basis for assembly and disassembly of the CRM1 nuclear export complex. Nature Structural & Molecular Biology. 16: 558-60. PMID 19339972 DOI: 10.1038/nsmb.1586  1
2009 Dong X, Biswas A, Süel KE, Jackson LK, Martinez R, Gu H, Chook YM. Structural basis for leucine-rich nuclear export signal recognition by CRM1. Nature. 458: 1136-41. PMID 19339969 DOI: 10.1038/nature07975  1
2008 Süel KE, Gu H, Chook YM. Modular organization and combinatorial energetics of proline-tyrosine nuclear localization signals. Plos Biology. 6: e137. PMID 18532879 DOI: 10.1371/journal.pbio.0060137  1
2007 Cansizoglu AE, Chook YM. Conformational heterogeneity of karyopherin beta2 is segmental. Structure (London, England : 1993). 15: 1431-41. PMID 17997969 DOI: 10.1016/j.str.2007.09.009  1
2007 Cansizoglu AE, Lee BJ, Zhang ZC, Fontoura BM, Chook YM. Structure-based design of a pathway-specific nuclear import inhibitor. Nature Structural & Molecular Biology. 14: 452-4. PMID 17435768 DOI: 10.1038/nsmb1229  1
2006 Süel KE, Cansizoglu AE, Chook YM. Atomic resolution structures in nuclear transport. Methods (San Diego, Calif.). 39: 342-55. PMID 16938467 DOI: 10.1016/j.ymeth.2006.06.015  1
2006 Lee BJ, Cansizoglu AE, Süel KE, Louis TH, Zhang Z, Chook YM. Rules for nuclear localization sequence recognition by karyopherin beta 2. Cell. 126: 543-58. PMID 16901787 DOI: 10.1016/j.cell.2006.05.049  1
2006 Faria AM, Levay A, Wang Y, Kamphorst AO, Rosa ML, Nussenzveig DR, Balkan W, Chook YM, Levy DE, Fontoura BM. The nucleoporin Nup96 is required for proper expression of interferon-regulated proteins and functions. Immunity. 24: 295-304. PMID 16546098 DOI: 10.1016/j.immuni.2006.01.014  1
2004 Wang W, Yang X, Kawai T, López de Silanes I, Mazan-Mamczarz K, Chen P, Chook YM, Quensel C, Köhler M, Gorospe M. AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR. The Journal of Biological Chemistry. 279: 48376-88. PMID 15342649 DOI: 10.1074/jbc.M409014200  0.01
2002 Chook YM, Jung A, Rosen MK, Blobel G. Uncoupling Kapbeta2 substrate dissociation and ran binding. Biochemistry. 41: 6955-66. PMID 12033928 DOI: 10.1021/bi012122p  1
2001 Chook YM, Blobel G. Karyopherins and nuclear import. Current Opinion in Structural Biology. 11: 703-15. PMID 11751052 DOI: 10.1016/S0959-440X(01)00264-0  1
1999 Chook YM, Cingolani G, Conti E, Stewart M, Vetter I, Wittinghofer A. Pictures in cell biology. Structures of nuclear-transport components. Trends in Cell Biology. 9: 310-1. PMID 10490335 DOI: 10.1016/S0962-8924(99)01610-4  1
1999 Chook YM, Blobel G. Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp. Nature. 399: 230-7. PMID 10353245 DOI: 10.1038/20375  1
1998 Chook YM, Lipscomb WN, Ke H. Detection and use of pseudo-translation in determination of protein structures. Acta Crystallographica. Section D, Biological Crystallography. 54: 822-7. PMID 9757096 DOI: 10.1107/S0907444997020064  1
1997 Kubiseski TJ, Chook YM, Parris WE, Rozakis-Adcock M, Pawson T. High affinity binding of the pleckstrin homology domain of mSos1 to phosphatidylinositol (4,5)-bisphosphate. The Journal of Biological Chemistry. 272: 1799-804. PMID 8999863 DOI: 10.1074/jbc.272.3.1799  1
1996 Chook YM, Gish GD, Kay CM, Pai EF, Pawson T. The Grb2-mSos1 complex binds phosphopeptides with higher affinity than Grb2. The Journal of Biological Chemistry. 271: 30472-8. PMID 8940013 DOI: 10.1074/jbc.271.48.30472  1
1994 Chook YM, Gray JV, Ke H, Lipscomb WN. The monofunctional chorismate mutase from Bacillus subtilis. Structure determination of chorismate mutase and its complexes with a transition state analog and prephenate, and implications for the mechanism of the enzymatic reaction. Journal of Molecular Biology. 240: 476-500. PMID 8046752 DOI: 10.1006/jmbi.1994.1462  1
1993 Chook YM, Ke H, Lipscomb WN. Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog. Proceedings of the National Academy of Sciences of the United States of America. 90: 8600-3. PMID 8378335  1
1991 Stevens RC, Chook YM, Cho CY, Lipscomb WN, Kantrowitz ER. Escherichia coli aspartate carbamoyltransferase: the probing of crystal structure analysis via site-specific mutagenesis. Protein Engineering. 4: 391-408. PMID 1881865 DOI: 10.1093/protein/4.4.391  1
1990 Chey J, Choe HS, Chook YM, Jensen E, Seida PR, Francl MM. π-Complexes of alkenes to trivalent aluminum Organometallics. 9: 2430-2436.  1
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