Matthew F. Krummel - Publications

Affiliations: 
Biomedical Sciences University of California, San Francisco, San Francisco, CA 
Area:
Immunology, Cell Biology

146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Neyton LPA, Patel RK, Sarma A, Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK. Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19. Nature Communications. 15: 5483. PMID 38942804 DOI: 10.1038/s41467-024-49756-2  0.349
2023 Ray A, Hu KH, Kersten K, Kuhn NF, Samad B, Combes AJ, Krummel MF. Critical role of CD206+ macrophages in organizing anti-tumor immunity. Biorxiv : the Preprint Server For Biology. PMID 37961697 DOI: 10.1101/2023.10.31.560822  0.311
2023 Ray A, Bassette M, Hu KH, Pass LF, Samad B, Combes A, Johri V, Davidson B, Hernandez G, Zaleta-Linares I, Krummel MF. Multimodal identification of rare potent effector CD8 T cells in solid tumors. Biorxiv : the Preprint Server For Biology. PMID 37808790 DOI: 10.1101/2023.09.26.559470  0.473
2023 Reina-Campos M, Heeg M, Kennewick K, Mathews IT, Galletti G, Luna V, Nguyen Q, Huang H, Milner JJ, Hu KH, Vichaidit A, Santillano N, Boland BS, Chang JT, Jain M, ... ... Krummel MF, et al. Metabolic programs of T cell tissue residency empower tumour immunity. Nature. PMID 37648857 DOI: 10.1038/s41586-023-06483-w  0.446
2023 Juric V, Mayes E, Binnewies M, Lee T, Canaday P, Pollack JL, Rudolph J, Du X, Liu VM, Dash S, Palmer R, Jahchan NS, Ramoth ÅJ, Lacayo S, Mankikar S, ... ... Krummel MF, et al. TREM1 activation of myeloid cells promotes antitumor immunity. Science Translational Medicine. 15: eadd9990. PMID 37647386 DOI: 10.1126/scitranslmed.add9990  0.363
2023 Tanaka M, Lum L, Hu K, Ledezma-Soto C, Superville D, Ng K, Adams Z, Kersten K, Fong L, Krummel M, Reeves M. Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma. Biorxiv : the Preprint Server For Biology. PMID 37162860 DOI: 10.1101/2023.04.25.538140  0.38
2023 Rahim MK, Okholm TLH, Jones KB, McCarthy EE, Liu CC, Yee JL, Tamaki SJ, Marquez DM, Tenvooren I, Wai K, Cheung A, Davidson BR, Johri V, Samad B, O'Gorman WE, ... Krummel MF, et al. Dynamic CD8 T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes. Cell. 186: 1127-1143.e18. PMID 36931243 DOI: 10.1016/j.cell.2023.02.021  0.419
2022 Beppler C, Eichorst J, Marchuk K, Cai E, Castellanos CA, Sriram V, Roybal KT, Krummel MF. Hyperstabilization of T cell microvilli contacts by chimeric antigen receptors. The Journal of Cell Biology. 222. PMID 36520493 DOI: 10.1083/jcb.202205118  0.667
2022 Yi R, Chen E, Roberts EW, Krummel MF, Serwas NK. Impact of protein identity on tumor-associated antigen uptake into infiltrating immune cells: A comparison of different fluorescent proteins as model antigens. Plos One. 17: e0272857. PMID 35976946 DOI: 10.1371/journal.pone.0272857  0.321
2022 Cai E, Beppler C, Eichorst J, Marchuk K, Eastman SW, Krummel MF. T cells use distinct topographical and membrane receptor scanning strategies that individually coalesce during receptor recognition. Proceedings of the National Academy of Sciences of the United States of America. 119: e2203247119. PMID 35914144 DOI: 10.1073/pnas.2203247119  0.63
2022 Burnett CE, Okholm TLH, Tenvooren I, Marquez DM, Tamaki S, Munoz Sandoval P, Willmore A, Hendrickson CM, Kangelaris KN, Langelier CR, Krummel MF, Woodruff PG, Calfee CS, Erle DJ, Ansel KM, et al. Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients. Immunity. 55: 1284-1298.e3. PMID 35779527 DOI: 10.1016/j.immuni.2022.06.004  0.338
2022 Kersten K, Hu KH, Combes AJ, Samad B, Harwin T, Ray A, Rao AA, Cai E, Marchuk K, Artichoker J, Courau T, Shi Q, Belk J, Satpathy AT, Krummel MF. Spatiotemporal co-dependency between macrophages and exhausted CD8 T cells in cancer. Cancer Cell. 40: 624-638.e9. PMID 35623342 DOI: 10.1016/j.ccell.2022.05.004  0.735
2022 You R, Artichoker J, Ray A, Gonzalez Velozo H, Rock DA, Conner KP, Krummel MF. Visualizing Spatial and Stoichiometric Barriers to Bispecific T-Cell Engager Efficacy. Cancer Immunology Research. 10: 698-712. PMID 35413104 DOI: 10.1158/2326-6066.CIR-21-0594  0.373
2022 Mujal AM, Combes AJ, Rao AA, Binnewies M, Samad B, Tsui J, Boissonnas A, Pollack JL, Argüello RJ, Meng MV, Porten SP, Ruhland MK, Barry KC, Chan V, Krummel MF. Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer. Cancer Immunology Research. PMID 35181780 DOI: 10.1158/2326-6066.CIR-21-0588  0.715
2021 Combes AJ, Samad B, Tsui J, Chew NW, Yan P, Reeder GC, Kushnoor D, Shen A, Davidson B, Barczak AJ, Adkisson M, Edwards A, Naser M, Barry KC, Courau T, ... ... Krummel MF, et al. Discovering dominant tumor immune archetypes in a pan-cancer census. Cell. PMID 34963056 DOI: 10.1016/j.cell.2021.12.004  0.625
2021 Mehta P, Gouirand V, Boda DP, Zhang J, Gearty SV, Zirak B, Lowe MM, Clancy S, Boothby I, Mahuron KM, Fries A, Krummel MF, Mankoo P, Chang HW, Liu J, et al. Layilin Anchors Regulatory T Cells in Skin. Journal of Immunology (Baltimore, Md. : 1950). PMID 34470859 DOI: 10.4049/jimmunol.2000970  0.383
2021 You R, Artichoker J, Fries A, Edwards AW, Combes AJ, Reeder GC, Samad B, Krummel MF. Active surveillance characterizes human intratumoral T cell exhaustion. The Journal of Clinical Investigation. PMID 34292884 DOI: 10.1172/JCI144353  0.479
2021 Cueto FJ, Del Fresno C, Brandi P, Combes AJ, Hernández-García E, Sánchez-Paulete AR, Enamorado M, Bromley CP, Gomez MJ, Conde-Garrosa R, Mañes S, Zelenay S, Melero I, Iborra S, Krummel MF, et al. DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells. Journal For Immunotherapy of Cancer. 9. PMID 33980589 DOI: 10.1136/jitc-2020-002054  0.348
2021 Seed RI, Kobayashi K, Ito S, Takasaka N, Cormier A, Jespersen JM, Publicover J, Trilok S, Combes AJ, Chew NW, Chapman J, Krummel MF, Lou J, Marks J, Cheng Y, et al. A tumor-specific mechanism of T enrichment mediated by the integrin αvβ8. Science Immunology. 6. PMID 33771888 DOI: 10.1126/sciimmunol.abf0558  0.395
2020 Bald T, Krummel MF, Smyth MJ, Barry KC. The NK cell-cancer cycle: advances and new challenges in NK cell-based immunotherapies. Nature Immunology. PMID 32690952 DOI: 10.1038/S41590-020-0728-Z  0.706
2020 Hu KH, Eichorst JP, McGinnis CS, Patterson DM, Chow ED, Kersten K, Jameson SC, Gartner ZJ, Rao AA, Krummel MF. ZipSeq: barcoding for real-time mapping of single cell transcriptomes. Nature Methods. PMID 32632238 DOI: 10.1038/S41592-020-0880-2  0.402
2020 Ruhland MK, Roberts EW, Cai E, Mujal AM, Marchuk K, Beppler C, Nam D, Serwas NK, Binnewies M, Krummel MF. Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells. Cancer Cell. 37: 786-799.e5. PMID 32516589 DOI: 10.1016/J.Ccell.2020.05.002  0.665
2020 Levine LS, Mahuron KM, Tsai KK, Wu C, Mattis DM, Pauli ML, Oglesby A, Lee JC, Spitzer MH, Krummel MF, Algazi AP, Rosenblum MD, Alvarado M, Daud AI. Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma. Annals of Surgical Oncology. PMID 32488521 DOI: 10.1245/S10434-020-08648-7  0.307
2020 Thumkeo D, Katsura Y, Nishimura Y, Kanchanawong P, Tohyama K, Ishizaki T, Kitajima S, Takahashi C, Hirata T, Watanabe N, Krummel MF, Narumiya S. mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse. Science Advances. 6: eaay2432. PMID 31911947 DOI: 10.1126/Sciadv.Aay2432  0.438
2020 Hu KH, Krummel MF. Carpet-bombing tumors with IFN-γ Nature Cancer. 1: 270-272. DOI: 10.1038/S43018-020-0042-6  0.401
2019 Lowe MM, Boothby I, Clancy S, Ahn RS, Liao W, Nguyen DN, Schumann K, Marson A, Mahuron KM, Kingsbury GA, Liu Z, Munoz Sandoval P, Rodriguez RS, Pauli ML, Taravati K, ... ... Krummel MF, et al. Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues. Jci Insight. 4. PMID 31852848 DOI: 10.1172/Jci.Insight.129756  0.342
2019 Wculek SK, Cueto FJ, Mujal AM, Melero I, Krummel MF, Sancho D. Dendritic cells in cancer immunology and immunotherapy. Nature Reviews. Immunology. PMID 31467405 DOI: 10.1038/S41577-019-0210-Z  0.357
2019 Jahchan NS, Mujal AM, Pollack JL, Binnewies M, Sriram V, Reyno L, Krummel MF. Tuning the Tumor Myeloid Microenvironment to Fight Cancer. Frontiers in Immunology. 10: 1611. PMID 31402908 DOI: 10.3389/Fimmu.2019.01611  0.408
2019 Puttur F, Denney L, Gregory LG, Vuononvirta J, Oliver R, Entwistle LJ, Walker SA, Headley MB, McGhee EJ, Pease JE, Krummel MF, Carlin LM, Lloyd CM. Pulmonary environmental cues drive group 2 innate lymphoid cell dynamics in mice and humans. Science Immunology. 4. PMID 31175176 DOI: 10.1126/Sciimmunol.Aav7638  0.316
2019 Binnewies M, Mujal AM, Pollack JL, Combes AJ, Hardison EA, Barry KC, Tsui J, Ruhland MK, Kersten K, Abushawish MA, Spasic M, Giurintano JP, Chan V, Daud AI, Ha P, ... ... Krummel MF, et al. Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4 T Cell Immunity. Cell. PMID 30955881 DOI: 10.1016/J.Cell.2019.02.005  0.752
2019 Dodagatta-Marri E, Meyer DS, Reeves MQ, Paniagua R, To MD, Binnewies M, Broz ML, Mori H, Wu D, Adoumie M, Del Rosario R, Li O, Buchmann T, Liang B, Malato J, ... ... Krummel MF, et al. α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas. Journal For Immunotherapy of Cancer. 7: 62. PMID 30832732 DOI: 10.1186/S40425-018-0493-9  0.357
2019 Dahlgren MW, Jones SW, Cautivo KM, Dubinin A, Ortiz-Carpena JF, Farhat S, Yu KS, Lee K, Wang C, Molofsky AV, Tward AD, Krummel MF, Peng T, Molofsky AB. Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches. Immunity. PMID 30824323 DOI: 10.1016/J.Immuni.2019.02.002  0.422
2019 Barry KC, Krummel MF. Abstract PR04: A natural killer–dendritic cell axis defines checkpoint therapy–responsive tumor microenvironments Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-Pr04  0.751
2019 Ruhland MK, Roberts EW, Krummel MF. Abstract B184: Modulating antigen flow to control immune tolerance Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B184  0.407
2019 Cai E, Marchuk K, Beppler C, Krummel M. Abstract B148: Microvilli enable efficient T-cell antigen search and ligand detection Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B148  0.763
2018 Krummel MF, Mahale JN, Uhl LFK, Hardison EA, Mujal AM, Mazet JM, Weber RJ, Gartner ZJ, Gérard A. Paracrine costimulation of IFN-γ signaling by integrins modulates CD8 T cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30348790 DOI: 10.1073/Pnas.1804556115  0.549
2018 Hung LY, Sen D, Oniskey TK, Katzen J, Cohen NA, Vaughan AE, Nieves W, Urisman A, Beers MF, Krummel MF, Herbert DR. Macrophages promote epithelial proliferation following infectious and non-infectious lung injury through a Trefoil factor 2-dependent mechanism. Mucosal Immunology. PMID 30337651 DOI: 10.1038/S41385-018-0096-2  0.316
2018 Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, ... ... Krummel MF, et al. A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments. Nature Medicine. PMID 29942093 DOI: 10.1038/S41591-018-0085-8  0.76
2018 Bąbała N, Bovens A, de Vries E, Iglesias-Guimarais V, Ahrends T, Krummel MF, Borst J, Bins AD. Subcellular localization of antigen dictates delivery of CD4+ T-cell help for the CTL response upon therapeutic DNA vaccination into the skin. Cancer Immunology Research. PMID 29764836 DOI: 10.1158/2326-6066.Cir-17-0408  0.423
2018 Binnewies M, Roberts EW, Kersten K, Chan V, Fearon DF, Merad M, Coussens LM, Gabrilovich DI, Ostrand-Rosenberg S, Hedrick CC, Vonderheide RH, Pittet MJ, Jain RK, Zou W, Howcroft TK, ... ... Krummel MF, et al. Understanding the tumor immune microenvironment (TIME) for effective therapy. Nature Medicine. PMID 29686425 DOI: 10.1038/S41591-018-0014-X  0.305
2018 Hung LY, Oniskey TK, Sen D, Krummel MF, Vaughan AE, Cohen NA, Herbert DR. Trefoil factor 2 promotes Type 2 immunity and lung repair through intrinsic roles in hematopoietic and non-hematopoietic cells. The American Journal of Pathology. PMID 29458008 DOI: 10.1016/J.Ajpath.2018.01.020  0.307
2018 de Mingo Pulido Á, Gardner A, Hiebler S, Soliman H, Rugo HS, Krummel MF, Coussens LM, Ruffell B. TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer. Cancer Cell. 33: 60-74.e6. PMID 29316433 DOI: 10.1016/J.Ccell.2017.11.019  0.416
2018 Mujal A, Barry K, Roberts E, Binnewies M, Ruhland M, Chan V, Krummel MF. Abstract IA05: Imaging- and single cell- based insights into the antitumor immune responses Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-Ia05  0.706
2017 Loo K, Tsai KK, Mahuron K, Liu J, Pauli ML, Sandoval PM, Nosrati A, Lee J, Chen L, Hwang J, Levine LS, Krummel MF, Algazi AP, Alvarado MD, Rosenblum MD, et al. Partially exhausted tumor-infiltrating lymphocytes predict response to combination immunotherapy. Jci Insight. 2. PMID 28724802 DOI: 10.1172/Jci.Insight.93433  0.383
2017 Cai E, Marchuk K, Beemiller P, Beppler C, Rubashkin MG, Weaver VM, Gérard A, Liu TL, Chen BC, Betzig E, Bartumeus F, Krummel MF. Visualizing dynamic microvillar search and stabilization during ligand detection by T cells. Science (New York, N.Y.). 356. PMID 28495700 DOI: 10.1126/Science.Aal3118  0.717
2017 Tumeh PC, Hellmann MD, Hamid O, Tsai KK, Loo KL, Gubens MA, Rosenblum M, Harview CL, Taube J, Handley N, Khurana N, Nosrati A, Krummel MF, Tucker A, Sosa E, et al. Liver Metastasis and Treatment Outcome with anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC. Cancer Immunology Research. PMID 28411193 DOI: 10.1158/2326-6066.Cir-16-0325  0.321
2016 Boldajipour B, Nelson A, Krummel MF. Tumor-infiltrating lymphocytes are dynamically desensitized to antigen but are maintained by homeostatic cytokine. Jci Insight. 1: e89289. PMID 27942588 DOI: 10.1172/Jci.Insight.89289  0.461
2016 Chong SZ, Evrard M, Devi S, Chen J, Lim JY, See P, Zhang Y, Adrover JM, Lee B, Tan L, Li JL, Liong KH, Phua C, Balachander A, Boey A, ... ... Krummel MF, et al. CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses. The Journal of Experimental Medicine. 213: 2293-2314. PMID 27811056 DOI: 10.1084/Jem.20160800  0.305
2016 Starobinets H, Ye J, Broz M, Barry K, Goldsmith J, Marsh T, Rostker F, Krummel M, Debnath J. Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment. The Journal of Clinical Investigation. PMID 27775547 DOI: 10.1172/Jci85705  0.692
2016 Sen D, Jones SM, Oswald EM, Pinkard H, Corbin K, Krummel MF. Tracking the Spatial and Functional Gradient of Monocyte-To-Macrophage Differentiation in Inflamed Lung. Plos One. 11: e0165064. PMID 27755611 DOI: 10.1371/Journal.Pone.0165064  0.454
2016 Loyher PL, Rochefort J, Baudesson de Chanville C, Hamon P, Lescaille G, Bertolus C, Guillot-Delost M, Krummel M, Lemoine FM, Combadière C, Boissonnas A. CCR2 influences T regulatory cell migration to tumors and serves as a biomarker of cyclophosphamide sensitivity. Cancer Research. PMID 27680685 DOI: 10.1158/0008-5472.Can-16-0984  0.477
2016 Thanabalasuriar A, Neupane AS, Wang J, Krummel MF, Kubes P. iNKT Cell Emigration out of the Lung Vasculature Requires Neutrophils and Monocyte-Derived Dendritic Cells in Inflammation. Cell Reports. 16: 3260-72. PMID 27653688 DOI: 10.1016/J.Celrep.2016.07.052  0.471
2016 Roberts EW, Broz ML, Binnewies M, Headley MB, Nelson AE, Wolf DM, Kaisho T, Bogunovic D, Bhardwaj N, Krummel MF. Critical Role for CD103(+)/CD141(+) Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma. Cancer Cell. PMID 27424807 DOI: 10.1016/J.Ccell.2016.06.003  0.552
2016 Headley MB, Bins A, Nip A, Roberts EW, Looney MR, Gerard A, Krummel MF. Visualization of immediate immune responses to pioneer metastatic cells in the lung. Nature. PMID 26982733 DOI: 10.1038/Nature16985  0.432
2016 Krummel MF, Bartumeus F, Gérard A. T cell migration, search strategies and mechanisms. Nature Reviews. Immunology. PMID 26852928 DOI: 10.1038/Nri.2015.16  0.612
2016 Roberts EW, Headley MB, Broz M, Boldjipour B, Corbin K, Binnewies M, Bins A, Gerard AA, Krummel M. Abstract IA32: Visualizing tumor immune interaction in real time Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-Ia32  0.393
2016 Maller O, Cassereau L, Drain A, Ruffell B, Acerbi I, Broz M, Munson J, Swartz M, Krummel M, Coussens L, Weaver V. Abstract A098: A role for fibrosis in promoting pro-tumor immune response in breast cancer Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A098  0.392
2016 Jones LM, Broz M, Ranger J, Ursini-Siegel J, Krummel M, Muller WJ. Abstract A02: Stat3 plays a critical role in the establishment of immunosuppressive tumor microenvironment: Implications for tumor immunsurviellance and metastatic progression Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-A02  0.347
2015 Mujal AM, Gilden JK, Gérard A, Kinoshita M, Krummel MF. A septin requirement differentiates autonomous and contact-facilitated T cell proliferation. Nature Immunology. PMID 26692174 DOI: 10.1038/Ni.3330  0.849
2015 Plaks V, Boldajipour B, Linnemann JR, Nguyen NH, Kersten K, Wolf Y, Casbon AJ, Kong N, van den Bijgaart RJ, Sheppard D, Melton AC, Krummel MF, Werb Z. Adaptive Immune Regulation of Mammary Postnatal Organogenesis. Developmental Cell. 34: 493-504. PMID 26321127 DOI: 10.1016/J.Devcel.2015.07.015  0.41
2015 Hashimoto M, Yanagisawa H, Minagawa S, Sen D, Ma R, Murray LA, Tsui P, Lou J, Marks JD, Baron JL, Krummel MF, Nishimura SL. TGF-β-Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease. Journal of Immunology (Baltimore, Md. : 1950). 195: 1182-90. PMID 26109638 DOI: 10.4049/Jimmunol.1500348  0.316
2015 Broz ML, Krummel MF. The emerging understanding of myeloid cells as partners and targets in tumor rejection. Cancer Immunology Research. 3: 313-9. PMID 25847968 DOI: 10.1158/2326-6066.Cir-15-0041  0.489
2015 Bose O, Baluk P, Looney MR, Cheng LE, McDonald DM, Caughey GH, Krummel MF. Mast cells present protrusions into blood vessels upon tracheal allergen challenge in mice. Plos One. 10: e0118513. PMID 25789765 DOI: 10.1371/Journal.Pone.0118513  0.378
2015 Hashimoto M, Yanagisawa H, Minagawa S, Sen D, Goodsell A, Ma R, Moermans C, McKnelly KJ, Baron JL, Krummel MF, Nishimura SL. A critical role for dendritic cells in the evolution of IL-1β-mediated murine airway disease. Journal of Immunology (Baltimore, Md. : 1950). 194: 3962-9. PMID 25786688 DOI: 10.4049/Jimmunol.1403043  0.398
2015 Mujal AM, Krummel M. The subtle hands of self-reactivity in peripheral T cells. Nature Immunology. 16: 10-1. PMID 25521673 DOI: 10.1038/Ni.3060  0.48
2015 Lindsay RS, Corbin K, Mahne A, Levitt BE, Gebert MJ, Wigton EJ, Bradley BJ, Haskins K, Jacobelli J, Tang Q, Krummel MF, Friedman RS. Antigen recognition in the islets changes with progression of autoimmune islet infiltration. Journal of Immunology (Baltimore, Md. : 1950). 194: 522-30. PMID 25505281 DOI: 10.4049/Jimmunol.1400626  0.767
2015 Loo K, Tsai KK, Rosenblum M, Khurana N, Hwang J, Sanchez R, Broz M, Krummel M, Tumeh P, Algazi AP, Daud A. Deep profiling of tumor immune microenvironment (TME) with fluorescence activated cell sorting (FACS) in advanced melanoma. Journal of Clinical Oncology. 33: 9012-9012. DOI: 10.1200/Jco.2015.33.15_Suppl.9012  0.343
2015 Broz M, Binnewies M, Boldajipour B, Nelson A, Pollock J, Erle D, Barczak A, Rosenblum M, Daud A, Barber D, Amigorena S, Veer LJv', Sperling A, Wolf D, Krummel MF. Abstract B65: Dissecting the tumor myeloid compartment reveals rare activating antigen presenting cells, critical for T cell immunity Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-B65  0.536
2014 Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity. Cancer Cell. 26: 938. PMID 28898680 DOI: 10.1016/j.ccell.2014.11.010  0.478
2014 Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity. Cancer Cell. 26: 638-52. PMID 25446897 DOI: 10.1016/J.Ccell.2014.09.007  0.525
2014 Gérard A, Patino-Lopez G, Beemiller P, Nambiar R, Ben-Aissa K, Liu Y, Totah FJ, Tyska MJ, Shaw S, Krummel MF. Detection of rare antigen-presenting cells through T cell-intrinsic meandering motility, mediated by Myo1g. Cell. 158: 492-505. PMID 25083865 DOI: 10.1016/J.Cell.2014.05.044  0.568
2014 Friedman RS, Lindsay RS, Lilly JK, Nguyen V, Sorensen CM, Jacobelli J, Krummel MF. An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function. Proceedings of the National Academy of Sciences of the United States of America. 111: 9223-8. PMID 24927530 DOI: 10.1073/Pnas.1322193111  0.797
2014 Krummel MF, Friedman RS, Jacobelli J. Modes and mechanisms of T cell motility: roles for confinement and Myosin-IIA. Current Opinion in Cell Biology. 30: 9-16. PMID 24905977 DOI: 10.1016/J.Ceb.2014.05.003  0.765
2014 Patnode ML, Bando JK, Krummel MF, Locksley RM, Rosen SD. Leukotriene B4 amplifies eosinophil accumulation in response to nematodes. The Journal of Experimental Medicine. 211: 1281-8. PMID 24889202 DOI: 10.1084/Jem.20132336  0.336
2014 Van Dyken SJ, Mohapatra A, Nussbaum JC, Molofsky AB, Thornton EE, Ziegler SF, McKenzie AN, Krummel MF, Liang HE, Locksley RM. Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and γδ T cells. Immunity. 40: 414-24. PMID 24631157 DOI: 10.1016/J.Immuni.2014.02.003  0.349
2014 Boldajipour BA, Krummel MF. Abstract LB-150: Local maturation and inhibition of antitumor CD8 T-cell responses in a model of immunoevasive breast cancer Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-150  0.548
2013 Beemiller P, Krummel MF. Regulation of T-cell receptor signaling by the actin cytoskeleton and poroelastic cytoplasm. Immunological Reviews. 256: 148-59. PMID 24117819 DOI: 10.1111/Imr.12120  0.583
2013 Jacobelli J, Estin Matthews M, Chen S, Krummel MF. Activated T cell trans-endothelial migration relies on myosin-IIA contractility for squeezing the cell nucleus through endothelial cell barriers. Plos One. 8: e75151. PMID 24069389 DOI: 10.1371/Journal.Pone.0075151  0.561
2013 Nussbaum JC, Van Dyken SJ, von Moltke J, Cheng LE, Mohapatra A, Molofsky AB, Thornton EE, Krummel MF, Chawla A, Liang HE, Locksley RM. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature. 502: 245-8. PMID 24037376 DOI: 10.1038/Nature12526  0.345
2013 Gérard A, Khan O, Beemiller P, Oswald E, Hu J, Matloubian M, Krummel MF. Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells. Nature Immunology. 14: 356-63. PMID 23475183 DOI: 10.1038/Ni.2547  0.608
2013 Cheng LE, Hartmann K, Roers A, Krummel MF, Locksley RM. Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E. Immunity. 38: 166-75. PMID 23290520 DOI: 10.1016/J.Immuni.2012.09.022  0.472
2013 Gérard A, Beemiller P, Friedman RS, Jacobelli J, Krummel MF. Evolving immune circuits are generated by flexible, motile, and sequential immunological synapses. Immunological Reviews. 251: 80-96. PMID 23278742 DOI: 10.1111/Imr.12021  0.73
2013 Lelkes E, Looney MR, Krummel MF. 162 Cytokine. 63: 281. DOI: 10.1016/J.Cyto.2013.06.165  0.323
2013 Gérard A, Khan O, Beemiller P, Oswald E, Hu J, Matloubian M, Krummel MF. 91 Cytokine. 63: 264. DOI: 10.1016/J.Cyto.2013.06.094  0.57
2012 Zhang Y, Chen YC, Krummel MF, Rosen SD. Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 3914-24. PMID 22962684 DOI: 10.4049/Jimmunol.1201604  0.508
2012 Beemiller P, Jacobelli J, Krummel MF. Integration of the movement of signaling microclusters with cellular motility in immunological synapses. Nature Immunology. 13: 787-95. PMID 22751140 DOI: 10.1038/Ni.2364  0.481
2012 Thornton EE, Looney MR, Bose O, Sen D, Sheppard D, Locksley R, Huang X, Krummel MF. Spatiotemporally separated antigen uptake by alveolar dendritic cells and airway presentation to T cells in the lung. The Journal of Experimental Medicine. 209: 1183-99. PMID 22585735 DOI: 10.1084/Jem.20112667  0.445
2012 Engelhardt JJ, Boldajipour B, Beemiller P, Pandurangi P, Sorensen C, Werb Z, Egeblad M, Krummel MF. Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells. Cancer Cell. 21: 402-17. PMID 22439936 DOI: 10.1016/J.Ccr.2012.01.008  0.541
2012 Gilden JK, Peck S, Chen YC, Krummel MF. The septin cytoskeleton facilitates membrane retraction during motility and blebbing. The Journal of Cell Biology. 196: 103-14. PMID 22232702 DOI: 10.1083/Jcb.201105127  0.776
2012 Beemiller P, Jacobelli J, Krummel M. Imaging and Analysis of OT1 T Cell Activation on Lipid Bilayers Protocol Exchange. DOI: 10.1038/Protex.2012.028  0.451
2011 Khan O, Headley M, Gerard A, Wei W, Liu L, Krummel MF. Regulation of T cell priming by lymphoid stroma. Plos One. 6: e26138. PMID 22110583 DOI: 10.1371/Journal.Pone.0026138  0.588
2011 Krummel MF, Allison JP. Pillars article: CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. The journal of experimental medicine. 1995. 182: 459-465. Journal of Immunology (Baltimore, Md. : 1950). 187: 3459-65. PMID 21934097  0.345
2011 Looney MR, Thornton EE, Sen D, Lamm WJ, Glenny RW, Krummel MF. Stabilized imaging of immune surveillance in the mouse lung. Nature Methods. 8: 91-6. PMID 21151136 DOI: 10.1038/Nmeth.1543  0.325
2010 Friedman RS, Beemiller P, Sorensen CM, Jacobelli J, Krummel MF. Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics. The Journal of Experimental Medicine. 207: 2733-49. PMID 21041455 DOI: 10.1084/Jem.20091201  0.776
2010 Katzman SD, O'Gorman WE, Villarino AV, Gallo E, Friedman RS, Krummel MF, Nolan GP, Abbas AK. Duration of antigen receptor signaling determines T-cell tolerance or activation. Proceedings of the National Academy of Sciences of the United States of America. 107: 18085-90. PMID 20921406 DOI: 10.1073/Pnas.1010560107  0.788
2010 Jacobelli J, Friedman RS, Conti MA, Lennon-Dumenil AM, Piel M, Sorensen CM, Adelstein RS, Krummel MF. Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions. Nature Immunology. 11: 953-61. PMID 20835229 DOI: 10.1038/Ni.1936  0.739
2010 Beemiller P, Krummel MF. Mediation of T-cell activation by actin meshworks. Cold Spring Harbor Perspectives in Biology. 2: a002444. PMID 20702599 DOI: 10.1101/Cshperspect.A002444  0.443
2010 Gilden J, Krummel MF. Control of cortical rigidity by the cytoskeleton: emerging roles for septins. Cytoskeleton (Hoboken, N.J.). 67: 477-86. PMID 20540086 DOI: 10.1002/Cm.20461  0.785
2010 Krummel MF, Cahalan MD. The immunological synapse: a dynamic platform for local signaling. Journal of Clinical Immunology. 30: 364-72. PMID 20390326 DOI: 10.1007/S10875-010-9393-6  0.449
2010 Doh J, Kim M, Krummel MF. Cell-laden microwells for the study of multicellularity in lymphocyte fate decisions. Biomaterials. 31: 3422-8. PMID 20117834 DOI: 10.1016/J.Biomaterials.2010.01.018  0.496
2010 Doh J, Krummel MF. Immunological synapses within context: patterns of cell-cell communication and their application in T-T interactions. Current Topics in Microbiology and Immunology. 340: 25-50. PMID 19960307 DOI: 10.1007/978-3-642-03858-7_2  0.564
2009 Fife BT, Pauken KE, Eagar TN, Obu T, Wu J, Tang Q, Azuma M, Krummel MF, Bluestone JA. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nature Immunology. 10: 1185-92. PMID 19783989 DOI: 10.1038/Ni.1790  0.44
2009 Bullen A, Friedman RS, Krummel MF. Two-photon imaging of the immune system: a custom technology platform for high-speed, multicolor tissue imaging of immune responses. Current Topics in Microbiology and Immunology. 334: 1-29. PMID 19521679 DOI: 10.1007/978-3-540-93864-4_1  0.637
2009 Melli K, Friedman RS, Martin AE, Finger EB, Miao G, Szot GL, Krummel MF, Tang Q. Amplification of autoimmune response through induction of dendritic cell maturation in inflamed tissues. Journal of Immunology (Baltimore, Md. : 1950). 182: 2590-600. PMID 19234153 DOI: 10.4049/Jimmunol.0803543  0.739
2009 Jacobelli J, Bennett FC, Pandurangi P, Tooley AJ, Krummel MF. Myosin-IIA and ICAM-1 regulate the interchange between two distinct modes of T cell migration. Journal of Immunology (Baltimore, Md. : 1950). 182: 2041-50. PMID 19201857 DOI: 10.4049/Jimmunol.0803267  0.831
2009 Tooley AJ, Gilden J, Jacobelli J, Beemiller P, Trimble WS, Kinoshita M, Krummel MF. Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility. Nature Cell Biology. 11: 17-26. PMID 19043408 DOI: 10.1038/Ncb1808  0.792
2008 Egeblad M, Ewald AJ, Askautrud HA, Truitt ML, Welm BE, Bainbridge E, Peeters G, Krummel MF, Werb Z. Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy. Disease Models & Mechanisms. 1: 155-67; discussion 1. PMID 19048079 DOI: 10.1242/Dmm.000596  0.462
2008 Mamchak AA, Sullivan BM, Hou B, Lee LM, Gilden JK, Krummel MF, Locksley RM, DeFranco AL. Normal development and activation but altered cytokine production of Fyn-deficient CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 5374-85. PMID 18832694 DOI: 10.4049/Jimmunol.181.8.5374  0.827
2008 Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science (New York, N.Y.). 321: 843-7. PMID 18687966 DOI: 10.1126/Science.1159407  0.761
2008 Sabatos CA, Doh J, Chakravarti S, Friedman RS, Pandurangi PG, Tooley AJ, Krummel MF. A synaptic basis for paracrine interleukin-2 signaling during homotypic T cell interaction. Immunity. 29: 238-48. PMID 18674934 DOI: 10.1016/J.Immuni.2008.05.017  0.825
2008 Beemiller P, Krummel MF. Distinct functions for HS1 in chemosensory versus adhesive signaling. Nature Immunology. 9: 833-4. PMID 18645589 DOI: 10.1038/Ni0808-833  0.454
2008 Engelhardt JJ, Krummel MF. The importance of prolonged binding to antigen-presenting cells for T cell fate decisions. Immunity. 28: 143-5. PMID 18275826 DOI: 10.1016/J.Immuni.2008.01.006  0.57
2007 Krummel MF. Testing the organization of the immunological synapse. Current Opinion in Immunology. 19: 460-2. PMID 17689061 DOI: 10.1016/J.Coi.2007.06.006  0.444
2007 Krummel MF. Immunological synapses: breaking up may be good to do. Cell. 129: 653-5. PMID 17512399 DOI: 10.1016/J.Cell.2007.05.008  0.546
2006 Krummel MF, Macara I. Maintenance and modulation of T cell polarity. Nature Immunology. 7: 1143-9. PMID 17053799 DOI: 10.1038/Ni1404  0.529
2006 Friedman RS, Jacobelli J, Krummel MF. Surface-bound chemokines capture and prime T cells for synapse formation. Nature Immunology. 7: 1101-8. PMID 16964261 DOI: 10.1038/Ni1384  0.8
2006 Tang Q, Krummel MF. Imaging the function of regulatory T cells in vivo. Current Opinion in Immunology. 18: 496-502. PMID 16765579 DOI: 10.1016/J.Coi.2006.05.007  0.531
2006 Moldovan MC, Sabbagh L, Breton G, Sékaly RP, Krummel MF. Triggering of T cell activation via CD4 dimers. Journal of Immunology (Baltimore, Md. : 1950). 176: 5438-45. PMID 16622011 DOI: 10.4049/Jimmunol.176.9.5438  0.4
2006 Tang Q, Adams JY, Tooley AJ, Bi M, Fife BT, Serra P, Santamaria P, Locksley RM, Krummel MF, Bluestone JA. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nature Immunology. 7: 83-92. PMID 16311599 DOI: 10.1038/Ni1289  0.848
2006 Friedman RS, Jacobelli J, Krummel MF. Erratum: Corrigendum: Surface-bound chemokines capture and prime T cells for synapse formation Nature Immunology. 7: 1234-1234. DOI: 10.1038/Ni1106-1234A  0.662
2005 Friedman RS, Jacobelli J, Krummel MF. Mechanisms of T cell motility and arrest: deciphering the relationship between intra- and extracellular determinants. Seminars in Immunology. 17: 387-99. PMID 16219473 DOI: 10.1016/J.Smim.2005.09.006  0.795
2005 Okada T, Miller MJ, Parker I, Krummel MF, Neighbors M, Hartley SB, O'Garra A, Cahalan MD, Cyster JG. Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. Plos Biology. 3: e150. PMID 15857154 DOI: 10.1371/Journal.Pbio.0030150  0.561
2005 Tooley AJ, Jacobelli J, Moldovan MC, Douglas A, Krummel MF. T cell synapse assembly: proteins, motors and the underlying cell biology. Seminars in Immunology. 17: 65-75. PMID 15582489 DOI: 10.1016/J.Smim.2004.09.006  0.831
2004 Boisvert J, Edmondson S, Krummel MF. Immunological synapse formation licenses CD40-CD40L accumulations at T-APC contact sites. Journal of Immunology (Baltimore, Md. : 1950). 173: 3647-52. PMID 15356109 DOI: 10.4049/Jimmunol.173.6.3647  0.51
2004 Jacobelli J, Andres PG, Boisvert J, Krummel MF. New views of the immunological synapse: variations in assembly and function. Current Opinion in Immunology. 16: 345-52. PMID 15134784 DOI: 10.1016/J.Coi.2004.03.008  0.488
2004 Andres PG, Howland KC, Dresnek D, Edmondson S, Abbas AK, Krummel MF. CD28 signals in the immature immunological synapse. Journal of Immunology (Baltimore, Md. : 1950). 172: 5880-6. PMID 15128767 DOI: 10.4049/Jimmunol.172.10.5880  0.44
2004 Jacobelli J, Chmura SA, Buxton DB, Davis MM, Krummel MF. A single class II myosin modulates T cell motility and stopping, but not synapse formation. Nature Immunology. 5: 531-8. PMID 15064761 DOI: 10.1038/Ni1065  0.55
2002 Ehrlich LI, Ebert PJ, Krummel MF, Weiss A, Davis MM. Dynamics of p56lck translocation to the T cell immunological synapse following agonist and antagonist stimulation. Immunity. 17: 809-22. PMID 12479826 DOI: 10.1016/S1074-7613(02)00481-8  0.445
2002 Moss WC, Irvine DJ, Davis MM, Krummel MF. Quantifying signaling-induced reorientation of T cell receptors during immunological synapse formation. Proceedings of the National Academy of Sciences of the United States of America. 99: 15024-9. PMID 12415110 DOI: 10.1073/Pnas.192573999  0.544
2002 Richie LI, Ebert PJ, Wu LC, Krummel MF, Owen JJ, Davis MM. Imaging synapse formation during thymocyte selection: inability of CD3zeta to form a stable central accumulation during negative selection. Immunity. 16: 595-606. PMID 11970882 DOI: 10.1016/S1074-7613(02)00299-6  0.462
2002 Krummel MF, Davis MM. Dynamics of the immunological synapse: finding, establishing and solidifying a connection. Current Opinion in Immunology. 14: 66-74. PMID 11790534 DOI: 10.1016/S0952-7915(01)00299-0  0.415
2000 Krummel M, Wülfing C, Sumen C, Davis MM. Thirty-six views of T-cell recognition. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 1071-6. PMID 11186308 DOI: 10.1098/Rstb.2000.0644  0.569
2000 Krummel MF, Sjaastad MD, Wülfing C, Davis MM. Differential clustering of CD4 and CD3zeta during T cell recognition. Science (New York, N.Y.). 289: 1349-52. PMID 10958781 DOI: 10.1126/Science.289.5483.1349  0.434
2000 Kurts C, Carbone FR, Krummel MF, Koch KM, Miller JFAP, Heath WR. Correction: Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells Nature. 407: 413-413. DOI: 10.1038/35030185  0.346
1999 Davis MM, Wülfing C, Krummel MF, Savage PA, Xu J, Sumen C, Dustin ML, Chien YH. Visualizing T-cell recognition. Cold Spring Harbor Symposia On Quantitative Biology. 64: 243-51. PMID 11232292 DOI: 10.1101/Sqb.1999.64.243  0.468
1999 Kurts C, Carbone FR, Krummel MF, Koch KM, Miller JF, Heath WR. Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells. Nature. 398: 341-4. PMID 10192335 DOI: 10.1038/18692  0.436
1998 Allison JP, Chambers C, Hurwitz A, Sullivan T, Boitel B, Fournier S, Brunner M, Krummel M. A role for CTLA-4-mediated inhibitory signals in peripheral T cell tolerance? Novartis Foundation Symposium. 215: 92-8; discussion 98-. PMID 9760573 DOI: 10.1002/9780470515525.Ch7  0.582
1998 Allison J, Stephens LA, Kay TW, Kurts C, Heath WR, Miller JFAP, Krummel MF. The threshold for autoimmune T cell killing is influenced by B7-1 European Journal of Immunology. 28: 949-960. PMID 9541590 DOI: 10.1002/(Sici)1521-4141(199803)28:03<949::Aid-Immu949>3.0.Co;2-H  0.46
1997 Winkel KD, Kronin V, Krummel MF, Shortman K. The nature of the signals regulating CD8 T cell proliferative responses to CD8alpha+ or CD8alpha- dendritic cells. European Journal of Immunology. 27: 3350-9. PMID 9464823 DOI: 10.1002/Eji.1830271234  0.432
1997 Hurwitz AA, Sullivan TJ, Krummel MF, Sobel RA, Allison JP. Specific blockade of CTLA-4/B7 interactions results in exacerbated clinical and histologic disease in an actively-induced model of experimental allergic encephalomyelitis. Journal of Neuroimmunology. 73: 57-62. PMID 9058759 DOI: 10.1016/S0165-5728(96)00168-3  0.369
1996 Chambers CA, Krummel MF, Boitel B, Hurwitz A, Sullivan TJ, Fournier S, Cassell D, Brunner M, Allison JP. The role of CTLA-4 in the regulation and initiation of T-Cell responses Immunological Reviews. 27-46. PMID 9010718 DOI: 10.1111/J.1600-065X.1996.Tb00919.X  0.464
1996 Krummel MF, Allison JP. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. The Journal of Experimental Medicine. 183: 2533-40. PMID 8676074 DOI: 10.1084/Jem.183.6.2533  0.534
1996 Krummel MF, Sullivan TJ, Allison JP. Superantigen responses and co-stimulation: CD28 and CTLA-4 have opposing effects on T cell expansion in vitro and in vivo. International Immunology. 8: 519-23. PMID 8671638 DOI: 10.1093/Intimm/8.4.519  0.409
1996 Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science (New York, N.Y.). 271: 1734-6. PMID 8596936 DOI: 10.1126/Science.271.5256.1734  0.489
1995 Krummel MF, Allison JP. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. The Journal of Experimental Medicine. 182: 459-65. PMID 7543139 DOI: 10.1084/Jem.182.2.459  0.548
1995 Allison JP, Krummel MF. The Yin and Yang of T cell costimulation. Science (New York, N.Y.). 270: 932-3. PMID 7481795 DOI: 10.1126/Science.270.5238.932  0.501
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