| Year |
Citation |
Score |
| 2023 |
Ballinger ML, Pattnaik S, Mundra PA, Zaheed M, Rath E, Priestley P, Baber J, Ray-Coquard I, Isambert N, Causeret S, van der Graaf WTA, Puri A, Duffaud F, Le Cesne A, Seddon B, ... ... Ludwig T, ... ... Ludwig T, et al. Heritable defects in telomere and mitotic function selectively predispose to sarcomas. Science (New York, N.Y.). 379: 253-260. PMID 36656928 DOI: 10.1126/science.abj4784 |
0.309 |
|
| 2020 |
Park D, Bergin SM, Jones D, Ru P, Koivisto CS, Jeon YJ, Sizemore GM, Kladney RD, Hadjis A, Shakya R, Ludwig T. Ablation of the Brca1-Palb2 interaction phenocopies Fanconi anemia in mice. Cancer Research. PMID 32732220 DOI: 10.1158/0008-5472.Can-20-0486 |
0.468 |
|
| 2019 |
Park D, Shakya R, Koivisto C, Pitarresi JR, Szabolcs M, Kladney R, Hadjis A, Mace TA, Ludwig T. Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains. Plos One. 14: e0226714. PMID 31877165 DOI: 10.1371/Journal.Pone.0226714 |
0.501 |
|
| 2018 |
Sizemore GM, Balakrishnan S, Thies KA, Hammer AM, Sizemore ST, Trimboli AJ, Cuitiño MC, Steck SA, Tozbikian G, Kladney RD, Shinde N, Das M, Park D, Majumder S, Krishnan S, ... ... Ludwig T, et al. Stromal PTEN determines mammary epithelial response to radiotherapy. Nature Communications. 9: 2783. PMID 30018330 DOI: 10.1038/S41467-018-05266-6 |
0.383 |
|
| 2018 |
Chiang HC, Zhang X, Zhao X, Zhang C, Chen J, Garza P, Smith S, Ludwig T, Baer RJ, Li R, Hu Y. Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development. Scientific Reports. 8: 2731. PMID 29426838 DOI: 10.1038/s41598-018-21044-2 |
0.471 |
|
| 2018 |
Vázquez-Arreguín K, Maddox J, Kang J, Park D, Cano RR, Factor RE, Ludwig T, Tantin D. BRCA1 through its E3 Ligase Activity Regulates the Transcription Factor Oct1 and Carbohydrate Metabolism. Molecular Cancer Research : McR. PMID 29330289 DOI: 10.1158/1541-7786.Mcr-17-0364 |
0.433 |
|
| 2017 |
Chen CC, Kass EM, Yen WF, Ludwig T, Moynahan ME, Chaudhuri J, Jasin M. ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair. Proceedings of the National Academy of Sciences of the United States of America. PMID 28659469 DOI: 10.1073/Pnas.1706392114 |
0.426 |
|
| 2016 |
Li M, Cole F, Patel DS, Misenko SM, Her J, Malhowski A, Alhamza A, Zheng H, Baer R, Ludwig T, Jasin M, Nussenzweig A, Serrano L, Bunting SF. 53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1. Embo Reports. PMID 27670884 DOI: 10.15252/Embr.201642497 |
0.436 |
|
| 2016 |
Pitarresi JR, Liu X, Sharma SM, Cuitiño MC, Kladney RD, Mace TA, Donohue S, Nayak SG, Qu C, Lee J, Woelke SA, Trela S, LaPak K, Yu L, McElroy J, ... ... Ludwig T, et al. Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia (New York, N.Y.). 18: 541-52. PMID 27659014 DOI: 10.1016/J.Neo.2016.07.006 |
0.316 |
|
| 2016 |
Reczek CR, Shakya R, Miteva Y, Szabolcs M, Ludwig T, Baer R. The DNA resection protein CtIP promotes mammary tumorigenesis. Oncotarget. PMID 27058754 DOI: 10.18632/Oncotarget.8605 |
0.519 |
|
| 2016 |
Palmieri D, Scarpa M, Tessari A, Uka R, Amari F, Lee C, Richmond T, Foray C, Sheetz T, Braddom A, Burd CE, Parvin JD, Ludwig T, Croce CM, Coppola V. Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells. Oncotarget. PMID 26943034 DOI: 10.18632/Oncotarget.7813 |
0.329 |
|
| 2015 |
Mace TA, Shakya R, Elnaggar O, Wilson K, Komar HM, Yang J, Pitarresi JR, Young GS, Ostrowski MC, Ludwig T, Bekaii-Saab T, Bloomston M, Lesinski GB. Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer. Oncotarget. PMID 26575024 DOI: 10.18632/Oncotarget.6332 |
0.349 |
|
| 2015 |
Manuel ER, Chen J, D'Apuzzo M, Lampa MG, Kaltcheva TI, Thompson CB, Ludwig T, Chung V, Diamond DJ. Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors. Cancer Immunology Research. PMID 26134178 DOI: 10.1158/2326-6066.CIR-14-0214 |
0.31 |
|
| 2015 |
Chatterjee M, Ben-Josef E, Thomas DG, Morgan MA, Zalupski MM, Khan G, Andrew Robinson C, Griffith KA, Chen CS, Ludwig T, Bekaii-Saab T, Chakravarti A, Williams TM. Caveolin-1 is Associated with Tumor Progression and Confers a Multi-Modality Resistance Phenotype in Pancreatic Cancer. Scientific Reports. 5: 10867. PMID 26065715 DOI: 10.1038/Srep10867 |
0.357 |
|
| 2014 |
Simhadri S, Peterson S, Patel DS, Huo Y, Cai H, Bowman-Colin C, Miller S, Ludwig T, Ganesan S, Bhaumik M, Bunting SF, Jasin M, Xia B. Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice. The Journal of Biological Chemistry. 289: 24617-29. PMID 25016020 DOI: 10.1074/Jbc.M114.566141 |
0.459 |
|
| 2014 |
Polato F, Callen E, Wong N, Faryabi R, Bunting S, Chen HT, Kozak M, Kruhlak MJ, Reczek CR, Lee WH, Ludwig T, Baer R, Feigenbaum L, Jackson S, Nussenzweig A. CtIP-mediated resection is essential for viability and can operate independently of BRCA1. The Journal of Experimental Medicine. 211: 1027-36. PMID 24842372 DOI: 10.1084/Jem.20131939 |
0.345 |
|
| 2014 |
Sonabend AM, Bansal M, Guarnieri P, Lei L, Amendolara B, Soderquist C, Leung R, Yun J, Kennedy B, Sisti J, Bruce S, Bruce R, Shakya R, Ludwig T, Rosenfeld S, et al. The transcriptional regulatory network of proneural glioma determines the genetic alterations selected during tumor progression. Cancer Research. 74: 1440-51. PMID 24390738 DOI: 10.1158/0008-5472.Can-13-2150 |
0.326 |
|
| 2014 |
Mace T, Shakya R, Swanson B, Ludwig T, Elnaggar O, Komar H, Yang J, Young G, Frankel W, Muscarella P, Bekaii-Saab T, Bloomston M, Lesinski G. BMS-911543 inhibits viability of tumor and stromal cells and limits disease progression in genetically engineered mice with pancreatic cancer Journal For Immunotherapy of Cancer. 2. DOI: 10.1186/2051-1426-2-S3-P186 |
0.352 |
|
| 2013 |
Tian F, Sharma S, Zou J, Lin SY, Wang B, Rezvani K, Wang H, Parvin JD, Ludwig T, Canman CE, Zhang D. BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade. Proceedings of the National Academy of Sciences of the United States of America. 110: 13558-63. PMID 23901102 DOI: 10.1073/Pnas.1306534110 |
0.325 |
|
| 2013 |
Reczek CR, Szabolcs M, Stark JM, Ludwig T, Baer R. The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression. The Journal of Cell Biology. 201: 693-707. PMID 23712259 DOI: 10.1083/jcb.201302145 |
0.464 |
|
| 2013 |
Lucas AL, Shakya R, Lipsyc MD, Mitchel EB, Kumar S, Hwang C, Deng L, Devoe C, Chabot JA, Szabolcs M, Ludwig T, Chung WK, Frucht H. High prevalence of BRCA1 and BRCA2 germline mutations with loss of heterozygosity in a series of resected pancreatic adenocarcinoma and other neoplastic lesions. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3396-403. PMID 23658460 DOI: 10.1158/1078-0432.Ccr-12-3020 |
0.31 |
|
| 2013 |
Kass EM, Helgadottir HR, Chen CC, Barbera M, Wang R, Westermark UK, Ludwig T, Moynahan ME, Jasin M. Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase. Proceedings of the National Academy of Sciences of the United States of America. 110: 5564-9. PMID 23509290 DOI: 10.1073/Pnas.1216824110 |
0.485 |
|
| 2013 |
González F, Georgieva D, Vanoli F, Shi ZD, Stadtfeld M, Ludwig T, Jasin M, Huangfu D. Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state. Cell Reports. 3: 651-60. PMID 23478019 DOI: 10.1016/J.Celrep.2013.02.005 |
0.333 |
|
| 2013 |
Gupta A, Hunt CR, Pandita RK, Pae J, Komal K, Singh M, Shay JW, Kumar R, Ariizumi K, Horikoshi N, Hittelman WN, Guha C, Ludwig T, Pandita TK. T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice. Mutagenesis. 28: 263-70. PMID 23386701 DOI: 10.1093/Mutage/Ges080 |
0.326 |
|
| 2013 |
Shakya R, Gonda T, Quante M, Salas M, Kim S, Brooks J, Hirsch S, Davies J, Cullo A, Olive K, Wang TC, Szabolcs M, Tycko B, Ludwig T. Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma. Cancer Research. 73: 885-96. PMID 23204224 DOI: 10.1158/0008-5472.Can-12-1880 |
0.341 |
|
| 2013 |
Xing L, Salas M, Zhang H, Gittler J, Ludwig T, Lin CS, Murty VV, Silverman W, Arancio O, Tycko B. Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1). Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 30-43. PMID 23096997 DOI: 10.1007/S00335-012-9436-9 |
0.346 |
|
| 2013 |
Mace TA, Pitaressi J, Shakya R, Frankel W, Eubank T, Bekaii-Saab T, Bloomston M, Phelps M, Ludwig T, Ostrowski M, Lesinski GB. Genetically engineered murine pancreatic cancer models approximate immunophenotypic properties of human patients Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P163 |
0.366 |
|
| 2012 |
Yamamoto K, Wang Y, Jiang W, Liu X, Dubois RL, Lin CS, Ludwig T, Bakkenist CJ, Zha S. Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice. The Journal of Cell Biology. 198: 305-13. PMID 22869596 DOI: 10.1083/Jcb.201204098 |
0.342 |
|
| 2012 |
Li T, Kon N, Jiang L, Tan M, Ludwig T, Zhao Y, Baer R, Gu W. Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell. 149: 1269-83. PMID 22682249 DOI: 10.1016/J.Cell.2012.04.026 |
0.401 |
|
| 2012 |
Bunting SF, Callén E, Kozak ML, Kim JM, Wong N, López-Contreras AJ, Ludwig T, Baer R, Faryabi RB, Malhowski A, Chen HT, Fernandez-Capetillo O, D'Andrea A, Nussenzweig A. BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair. Molecular Cell. 46: 125-35. PMID 22445484 DOI: 10.1016/J.Molcel.2012.02.015 |
0.314 |
|
| 2011 |
Ramadas RA, Roche MI, Moon JJ, Ludwig T, Xavier RJ, Medoff BD. CARMA1 is necessary for optimal T cell responses in a murine model of allergic asthma. Journal of Immunology (Baltimore, Md. : 1950). 187: 6197-207. PMID 22075698 DOI: 10.4049/Jimmunol.1101348 |
0.312 |
|
| 2011 |
Shakya R, Reid LJ, Reczek CR, Cole F, Egli D, Lin CS, deRooij DG, Hirsch S, Ravi K, Hicks JB, Szabolcs M, Jasin M, Baer R, Ludwig T. BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity. Science (New York, N.Y.). 334: 525-8. PMID 22034435 DOI: 10.1126/Science.1209909 |
0.685 |
|
| 2011 |
Lei L, Sonabend AM, Guarnieri P, Soderquist C, Ludwig T, Rosenfeld S, Bruce JN, Canoll P. Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype. Plos One. 6: e20041. PMID 21625383 DOI: 10.1371/Journal.Pone.0020041 |
0.458 |
|
| 2011 |
Gambardella L, Anderson KE, Nussbaum C, Segonds-Pichon A, Margarido T, Norton L, Ludwig T, Sperandio M, Hawkins PT, Stephens L, Vermeren S. The GTPase-activating protein ARAP3 regulates chemotaxis and adhesion-dependent processes in neutrophils. Blood. 118: 1087-98. PMID 21490342 DOI: 10.1182/Blood-2010-10-312959 |
0.327 |
|
| 2011 |
Kon N, Zhong J, Kobayashi Y, Li M, Szabolcs M, Ludwig T, Canoll PD, Gu W. Roles of HAUSP-mediated p53 regulation in central nervous system development. Cell Death and Differentiation. 18: 1366-75. PMID 21350561 DOI: 10.1038/Cdd.2011.12 |
0.385 |
|
| 2011 |
Kumar R, Hunt CR, Gupta A, Nannepaga S, Pandita RK, Shay JW, Bachoo R, Ludwig T, Burns DK, Pandita TK. Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 3636-41. PMID 21321203 DOI: 10.1073/Pnas.1016524108 |
0.385 |
|
| 2010 |
Wu-Baer F, Ludwig T, Baer R. The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function. Molecular and Cellular Biology. 30: 2787-98. PMID 20351172 DOI: 10.1128/MCB.01056-09 |
0.391 |
|
| 2010 |
Su F, Smilenov LB, Ludwig T, Zhou L, Zhu J, Zhou G, Hall EJ. Hemizygosity for Atm and Brca1 influence the balance between cell transformation and apoptosis. Radiation Oncology (London, England). 5: 15. PMID 20175908 DOI: 10.1186/1748-717X-5-15 |
0.366 |
|
| 2009 |
Kon N, Kobayashi Y, Li M, Brooks CL, Ludwig T, Gu W. Inactivation of HAUSP in vivo modulates p53 function. Oncogene. 29: 1270-9. PMID 19946331 DOI: 10.1038/Onc.2009.427 |
0.354 |
|
| 2009 |
Jin N, Cho SN, Raso MG, Wistuba I, Smith Y, Yang Y, Kurie JM, Yen R, Evans CM, Ludwig T, Jeong JW, DeMayo FJ. Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis. Development (Cambridge, England). 136: 3347-56. PMID 19710174 DOI: 10.1242/Dev.032979 |
0.346 |
|
| 2008 |
Reid LJ, Shakya R, Modi AP, Lokshin M, Cheng JT, Jasin M, Baer R, Ludwig T. E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proceedings of the National Academy of Sciences of the United States of America. 105: 20876-81. PMID 19088202 DOI: 10.1073/Pnas.0811203106 |
0.685 |
|
| 2008 |
Xiang T, Ohashi A, Huang Y, Pandita TK, Ludwig T, Powell SN, Yang Q. Negative Regulation of AKT Activation by BRCA1. Cancer Research. 68: 10040-4. PMID 19074868 DOI: 10.1158/0008-5472.Can-08-3009 |
0.502 |
|
| 2008 |
Shakya R, Szabolcs M, McCarthy E, Ospina E, Basso K, Nandula S, Murty V, Baer R, Ludwig T. The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression. Proceedings of the National Academy of Sciences of the United States of America. 105: 7040-5. PMID 18443292 DOI: 10.1073/Pnas.0711032105 |
0.776 |
|
| 2008 |
Saal LH, Gruvberger-Saal SK, Persson C, Lövgren K, Jumppanen M, Staaf J, Jönsson G, Pires MM, Maurer M, Holm K, Koujak S, Subramaniyam S, Vallon-Christersson J, Olsson H, Su T, ... ... Ludwig T, et al. Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. Nature Genetics. 40: 102-7. PMID 18066063 DOI: 10.1038/Ng.2007.39 |
0.583 |
|
| 2008 |
Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK. The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Molecular and Cellular Biology. 28: 397-409. PMID 17967868 DOI: 10.1128/Mcb.01045-07 |
0.439 |
|
| 2007 |
Laufer M, Nandula SV, Modi AP, Wang S, Jasin M, Murty VV, Ludwig T, Baer R. Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair. The Journal of Biological Chemistry. 282: 34325-33. PMID 17848578 DOI: 10.1074/Jbc.M705198200 |
0.491 |
|
| 2007 |
Guo K, McMinn JE, Ludwig T, Yu YH, Yang G, Chen L, Loh D, Li C, Chua S, Zhang Y. Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities. Endocrinology. 148: 3987-97. PMID 17495001 DOI: 10.1210/En.2007-0261 |
0.326 |
|
| 2006 |
Ning Y, Schuller AG, Bradshaw S, Rotwein P, Ludwig T, Frystyk J, Pintar JE. Diminished growth and enhanced glucose metabolism in triple knockout mice containing mutations of insulin-like growth factor binding protein-3, -4, and -5. Molecular Endocrinology (Baltimore, Md.). 20: 2173-86. PMID 16675541 DOI: 10.1210/Me.2005-0196 |
0.361 |
|
| 2005 |
de Luca C, Kowalski TJ, Zhang Y, Elmquist JK, Lee C, Kilimann MW, Ludwig T, Liu SM, Chua SC. Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes. The Journal of Clinical Investigation. 115: 3484-93. PMID 16284652 DOI: 10.1172/Jci24059 |
0.315 |
|
| 2005 |
Ludwig T. Local proteolytic activity in tumor cell invasion and metastasis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 27: 1181-91. PMID 16237672 DOI: 10.1002/bies.20306 |
0.308 |
|
| 2005 |
Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature. 436: 725-30. PMID 16079851 DOI: 10.1038/Nature03918 |
0.338 |
|
| 2005 |
Coppari R, Ichinose M, Lee CE, Pullen AE, Kenny CD, McGovern RA, Tang V, Liu SM, Ludwig T, Chua SC, Lowell BB, Elmquist JK. The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity. Cell Metabolism. 1: 63-72. PMID 16054045 DOI: 10.1016/J.Cmet.2004.12.004 |
0.323 |
|
| 2005 |
Gupta A, Sharma GG, Young CS, Agarwal M, Smith ER, Paull TT, Lucchesi JC, Khanna KK, Ludwig T, Pandita TK. Involvement of human MOF in ATM function. Molecular and Cellular Biology. 25: 5292-305. PMID 15923642 DOI: 10.1128/Mcb.25.12.5292-5305.2005 |
0.414 |
|
| 2005 |
McMinn JE, Liu SM, Liu H, Dragatsis I, Dietrich P, Ludwig T, Boozer CN, Chua SC. Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertility. American Journal of Physiology. Endocrinology and Metabolism. 289: E403-11. PMID 15870101 DOI: 10.1152/Ajpendo.00535.2004 |
0.312 |
|
| 2005 |
Choudhury AD, Xu H, Modi AP, Zhang W, Ludwig T, Baer R. Hyperphosphorylation of the BARD1 tumor suppressor in mitotic cells. The Journal of Biological Chemistry. 280: 24669-79. PMID 15855157 DOI: 10.1074/jbc.M502446200 |
0.342 |
|
| 2005 |
Easton RM, Cho H, Roovers K, Shineman DW, Mizrahi M, Forman MS, Lee VM, Szabolcs M, de Jong R, Oltersdorf T, Ludwig T, Efstratiadis A, Birnbaum MJ. Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Molecular and Cellular Biology. 25: 1869-78. PMID 15713641 DOI: 10.1128/Mcb.25.5.1869-1878.2005 |
0.324 |
|
| 2005 |
Ludwig T, Püttmann S, Bertram H, Tatenhorst L, Paulus W, Oberleithner H, Senner V. Functional measurement of local proteolytic activity in living cells of invasive and non-invasive tumors. Journal of Cellular Physiology. 202: 690-7. PMID 15389570 DOI: 10.1002/Jcp.20168 |
0.321 |
|
| 2005 |
Klein U, Casola S, Cattoretti G, Shen Q, Lia M, Mo T, Ludwig T, Rajewsky K, Dalla-Favera R. IRF-4/MUM-1 Expression Is a Critical Switch in the Generation of Plasma Cells Versus Memory B-Cells. Blood. 106: 337-337. DOI: 10.1182/Blood.V106.11.337.337 |
0.357 |
|
| 2004 |
McMinn JE, Liu SM, Dragatsis I, Dietrich P, Ludwig T, Eiden S, Chua SC. An allelic series for the leptin receptor gene generated by CRE and FLP recombinase. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 677-85. PMID 15389315 DOI: 10.1007/S00335-004-2340-1 |
0.378 |
|
| 2004 |
Politi K, Szabolcs M, Fisher P, Kljuic A, Ludwig T, Efstratiadis A. A mouse model of uterine leiomyosarcoma. The American Journal of Pathology. 164: 325-36. PMID 14695345 DOI: 10.1016/S0002-9440(10)63122-7 |
0.365 |
|
| 2004 |
Politi K, Kljuic A, Szabolcs M, Fisher P, Ludwig T, Efstratiadis A. 'Designer' tumors in mice. Oncogene. 23: 1558-65. PMID 14661057 DOI: 10.1038/Sj.Onc.1207275 |
0.471 |
|
| 2003 |
Horiuchi K, Weskamp G, Lum L, Hammes HP, Cai H, Brodie TA, Ludwig T, Chiusaroli R, Baron R, Preissner KT, Manova K, Blobel CP. Potential role for ADAM15 in pathological neovascularization in mice. Molecular and Cellular Biology. 23: 5614-24. PMID 12897135 DOI: 10.1128/Mcb.23.16.5614-5624.2003 |
0.42 |
|
| 2003 |
McCarthy EE, Celebi JT, Baer R, Ludwig T. Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability. Molecular and Cellular Biology. 23: 5056-63. PMID 12832489 DOI: 10.1128/Mcb.23.14.5056-5063.2003 |
0.764 |
|
| 2002 |
Weskamp G, Cai H, Brodie TA, Higashyama S, Manova K, Ludwig T, Blobel CP. Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life. Molecular and Cellular Biology. 22: 1537-44. PMID 11839819 DOI: 10.1128/Mcb.22.5.1537-1544.2002 |
0.38 |
|
| 2002 |
Baer R, Ludwig T. The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity. Current Opinion in Genetics & Development. 12: 86-91. PMID 11790560 DOI: 10.1016/S0959-437X(01)00269-6 |
0.553 |
|
| 2001 |
Ludwig T, Fisher P, Murty V, Efstratiadis A. Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice. Oncogene. 20: 3937-48. PMID 11494122 DOI: 10.1038/Sj.Onc.1204512 |
0.564 |
|
| 2001 |
Ludwig T, Fisher P, Ganesan S, Efstratiadis A. Tumorigenesis in mice carrying a truncating Brca1 mutation. Genes & Development. 15: 1188-93. PMID 11358863 DOI: 10.1101/Gad.879201 |
0.589 |
|
| 1998 |
Sohar I, Sleat D, Gong Liu C, Ludwig T, Lobel P. Mouse mutants lacking the cation-independent mannose 6-phosphate/insulin-like growth factor II receptor are impaired in lysosomal enzyme transport: comparison of cation-independent and cation-dependent mannose 6-phosphate receptor-deficient mice. The Biochemical Journal. 330: 903-8. PMID 9480908 DOI: 10.1042/Bj3300903 |
0.337 |
|
| 1997 |
Ludwig T, Chapman DL, Papaioannou VE, Efstratiadis A. Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos. Genes & Development. 11: 1226-41. PMID 9171368 DOI: 10.1101/Gad.11.10.1226 |
0.546 |
|
| 1996 |
Ludwig T, Eggenschwiler J, Fisher P, D'Ercole AJ, Davenport ML, Efstratiadis A. Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds. Developmental Biology. 177: 517-35. PMID 8806828 DOI: 10.1006/Dbio.1996.0182 |
0.323 |
|
| 1994 |
Ludwig T, Munier-Lehmann H, Bauer U, Hollinshead M, Ovitt C, Lobel P, Hoflack B. Differential sorting of lysosomal enzymes in mannose 6-phosphate receptor-deficient fibroblasts. The Embo Journal. 13: 3430-3437. DOI: 10.1002/J.1460-2075.1994.Tb06648.X |
0.341 |
|
| 1993 |
Ludwig T, Ovitt C, Bauer U, Hollinshead M, Remmler J, Lobel P, Rüther U, Hoflack B. Targeted disruption of the mouse cation-dependent mannose 6-phosphate receptor results in partial missorting of multiple lysosomal enzymes. The Embo Journal. 12: 5225-5235. DOI: 10.1002/J.1460-2075.1993.Tb06218.X |
0.354 |
|
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