Kyle Landgraf - Publications

Affiliations: 
Genentech Inc., Oceanside, CA, United States 

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Landgraf KE, Steffek M, Quan C, Tom J, Yu C, Santell L, Maun HR, Eigenbrot C, Lazarus RA. An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides. Nature Chemical Biology. 10: 567-73. PMID 24859116 DOI: 10.1038/nchembio.1533  0.92
2014 Ziemba BP, Li J, Landgraf KE, Knight JD, Voth GA, Falke JJ. Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α. Biochemistry. 53: 1697-713. PMID 24559055 DOI: 10.1021/bi4016082  0.92
2012 Chen HC, Ziemba BP, Landgraf KE, Corbin JA, Falke JJ. Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study. Plos One. 7: e33640. PMID 22479423 DOI: 10.1371/journal.pone.0033640  0.92
2011 Pilling C, Landgraf KE, Falke JJ. The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3). Biochemistry. 50: 9845-56. PMID 21932773 DOI: 10.1021/bi2011306  0.92
2010 Landgraf KE, Santell L, Billeci KL, Quan C, Young JC, Maun HR, Kirchhofer D, Lazarus RA. Allosteric peptide activators of pro-hepatocyte growth factor stimulate Met signaling. The Journal of Biological Chemistry. 285: 40362-72. PMID 20937841 DOI: 10.1074/jbc.M110.179721  0.92
2010 Lai CL, Landgraf KE, Voth GA, Falke JJ. Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCα C2 domain: a combined molecular dynamics and experimental study. Journal of Molecular Biology. 402: 301-10. PMID 20659476 DOI: 10.1016/j.jmb.2010.07.037  0.92
2010 Hutchinson MR, Loram LC, Zhang Y, Shridhar M, Rezvani N, Berkelhammer D, Phipps S, Foster PS, Landgraf K, Falke JJ, Rice KC, Maier SF, Yin H, Watkins LR. Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity. Neuroscience. 168: 551-63. PMID 20381591 DOI: 10.1016/j.neuroscience.2010.03.067  0.92
2010 Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, et al. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain, Behavior, and Immunity. 24: 83-95. PMID 19679181 DOI: 10.1016/j.bbi.2009.08.004  0.92
2008 Landgraf KE, Pilling C, Falke JJ. Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain. Biochemistry. 47: 12260-9. PMID 18954143 DOI: 10.1021/bi801683k  0.92
2008 Landgraf KE, Malmberg NJ, Falke JJ. Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study. Biochemistry. 47: 8301-16. PMID 18610985 DOI: 10.1021/bi800711t  0.92
2007 Corbin JA, Evans JH, Landgraf KE, Falke JJ. Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity. Biochemistry. 46: 4322-36. PMID 17367165 DOI: 10.1021/bi062140c  0.92
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