| Year |
Citation |
Score |
| 2024 |
Casini A, Pöthig A. Metals in Cancer Research: Beyond Platinum Metallodrugs. Acs Central Science. 10: 242-250. PMID 38435529 DOI: 10.1021/acscentsci.3c01340 |
0.316 |
|
| 2023 |
Park M, Schmidt C, Türck S, Hanusch F, Hirmer SV, Ott I, Casini A, Inoue S. Potent Anticancer Activity of a Dinuclear Gold(I) Bis-N-Heterocyclic Imine Complex Related to Thioredoxin Reductase Inhibition in Vitro. Chempluschem. e202300557. PMID 37937471 DOI: 10.1002/cplu.202300557 |
0.319 |
|
| 2023 |
Deiser S, Drexler M, Moreno-Alcántar G, Irl M, Schmidt C, Günther T, Casini A. Synthesis of Lu-Labeled, Somatostatin-2 Receptor-Targeted Metalla-Assemblies: Challenges in the Design of Supramolecular Radiotherapeutics. Inorganic Chemistry. PMID 37556427 DOI: 10.1021/acs.inorgchem.3c02090 |
0.78 |
|
| 2023 |
Scalcon V, Bonsignore R, Aupič J, Thomas SR, Folda A, Heidecker AA, Pöthig A, Magistrato A, Casini A, Rigobello MP. Exploring the Anticancer Activity of Tamoxifen-Based Metal Complexes Targeting Mitochondria. Journal of Medicinal Chemistry. PMID 37410388 DOI: 10.1021/acs.jmedchem.3c00617 |
0.322 |
|
| 2023 |
Kumar NM, Gruhs P, Casini A, Biedermann F, Moreno-Alcántar G, Picchetti P. Electrochemical Detection of Drugs via a Supramolecular Cucurbit[7]uril-Based Indicator Displacement Assay. Acs Sensors. PMID 37339775 DOI: 10.1021/acssensors.3c00008 |
0.771 |
|
| 2023 |
Moreno-Alcántar G, Picchetti P, Casini A. Gold Complexes in Anticancer Therapy: From New Design Principles to Particle-Based Delivery Systems. Angewandte Chemie (International Ed. in English). e202218000. PMID 36847211 DOI: 10.1002/anie.202218000 |
0.791 |
|
| 2022 |
Kaußler C, Wragg D, Schmidt C, Moreno-Alcántar G, Jandl C, Stephan J, Fischer RA, Leoni S, Casini A, Bonsignore R. "Dynamical Docking" of Cyclic Dinuclear Au(I) Bis-N-heterocyclic Complexes Facilitates Their Binding to G-Quadruplexes. Inorganic Chemistry. PMID 36484812 DOI: 10.1021/acs.inorgchem.2c03041 |
0.798 |
|
| 2022 |
Moreno-Alcántar G, Casini A. Bioinorganic Supramolecular Coordination Complexes and Their Biomedical Applications. Febs Letters. PMID 36345593 DOI: 10.1002/1873-3468.14535 |
0.778 |
|
| 2022 |
Schmidt C, Zollo M, Bonsignore R, Casini A, Hacker SM. Competitive profiling of ligandable cysteines in with an organogold compound. Chemical Communications (Cambridge, England). 58: 5526-5529. PMID 35420608 DOI: 10.1039/d2cc01259f |
0.326 |
|
| 2020 |
Meier-Menches S, Neuditschko B, Zappe K, Schaier M, Gerner M, Schmetterer K, Del Favero G, Bonsignore R, Cichna-Makl M, Koellensperger G, Casini A, Gerner C. An organometallic gold(I) bis-N-heterocyclic carbene complex with multimodal activity in ovarian cancer cells. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32902006 DOI: 10.1002/Chem.202003495 |
0.42 |
|
| 2020 |
Minori K, Rosa LB, Bonsignore R, Casini A, Miguel DC. Comparing the antileishmanial activity of gold(I) and gold(III) compounds in L. amazonensis and L. braziliensisin vitro. Chemmedchem. PMID 32830445 DOI: 10.1002/Cmdc.202000536 |
0.355 |
|
| 2020 |
Kaur G, Javed W, Ponomarenko O, Shekh K, Swanlund DP, Zhou JR, Summers KL, Casini A, Wenzel M, Casey JR, Cordat E, Pickering IJ, George GN, Leslie EM. Human Red Blood Cell Uptake and Sequestration of Arsenite and Selenite: Evidence of Seleno-bis(S-glutathionyl) Arsinium Ion Formation in Human Cells. Biochemical Pharmacology. 114141. PMID 32652143 DOI: 10.1016/J.Bcp.2020.114141 |
0.317 |
|
| 2020 |
Thomas SR, Bonsignore R, Escudero Sanchez J, Meier-Menches SM, Brown C, Wolf M, Barone G, Luk LY, Casini A. Exploring the chemoselectivity towards cysteine arylation by cyclometalated Au(III) compounds: new mechanistic insights. Chembiochem : a European Journal of Chemical Biology. PMID 32511840 DOI: 10.1002/Cbic.202000262 |
0.366 |
|
| 2020 |
Han J, Sun J, Song S, Beljaars L, Groothuis GMM, Permentier H, Bischoff R, Halmos GB, Verhoeven CJ, Amstalden van Hove ER, Horvatovich P, Casini A. Targeted imaging of integrins in cancer tissues using photocleavable Ru(ii) polypyridine complexes as mass-tags. Chemical Communications (Cambridge, England). PMID 32347235 DOI: 10.1039/D0Cc00774A |
0.308 |
|
| 2020 |
Thomas SR, Casini A. Gold compounds for catalysis and metal-mediated transformations in biological systems. Current Opinion in Chemical Biology. 55: 103-110. PMID 32086166 DOI: 10.1016/J.Cbpa.2019.12.007 |
0.351 |
|
| 2020 |
Daga M, de Graaf IAM, Argenziano M, Barranco ASM, Loeck M, Mohammed Y, Cucci MA, Caldera F, Trotta F, Barrera G, Casini A, Cavalli R, Pizzimenti S. Glutathione-responsive cyclodextrin-nanosponges as drug delivery systems for doxorubicin: Evaluation of toxicity and transport mechanisms in the liver. Toxicology in Vitro : An International Journal Published in Association With Bibra. 104800. PMID 32084521 DOI: 10.1016/J.Tiv.2020.104800 |
0.308 |
|
| 2020 |
Bonsignore R, Thomas S, Klooster W, Coles S, Bourissou D, Jenkins R, Barone G, Casini A. Carbon-Phosphorus Coupling from C^N Cyclometalated Au(III) Complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31994237 DOI: 10.1002/Chem.201905392 |
0.354 |
|
| 2020 |
Oberkofler J, Aikman B, Bonsignore R, Pöthig A, Platts J, Casini A, Kühn FE. Exploring the Reactivity and Biological Effects of Heteroleptic N-Heterocyclic Carbene Gold(I)-Alkynyl Complexes European Journal of Inorganic Chemistry. 2020: 1040-1051. DOI: 10.1002/Ejic.201901043 |
0.422 |
|
| 2019 |
Estrada-Ortiz N, Lopez-Gonzales E, Woods B, Stürup S, de Graaf IAM, Groothuis GMM, Casini A. toxicological evaluation of experimental anticancer gold(i) complexes with lansoprazole-type ligands. Toxicology Research. 8: 885-895. PMID 32190293 DOI: 10.1039/C9Tx00149B |
0.469 |
|
| 2019 |
Meier-Menches SM, Aikman B, Döllerer D, Klooster WT, Coles SJ, Santi N, Luk L, Casini A, Bonsignore R. Comparative biological evaluation and G-quadruplex interaction studies of two new families of organometallic gold(I) complexes featuring N-heterocyclic carbene and alkynyl ligands. Journal of Inorganic Biochemistry. 202: 110844. PMID 31739113 DOI: 10.1016/J.Jinorgbio.2019.110844 |
0.434 |
|
| 2019 |
Woods B, Döllerer D, Aikman B, Wenzel MN, Sayers EJ, Kühn FE, Jones AT, Casini A. Highly luminescent metallacages featuring bispyridyl ligands functionalised with BODIPY for imaging in cancer cells. Journal of Inorganic Biochemistry. 199: 110781. PMID 31357067 DOI: 10.1016/J.Jinorgbio.2019.110781 |
0.37 |
|
| 2019 |
Pöthig A, Casini A. Recent Developments of Supramolecular Metal-based Structures for Applications in Cancer Therapy and Imaging. Theranostics. 9: 3150-3169. PMID 31244947 DOI: 10.7150/Thno.31828 |
0.383 |
|
| 2019 |
Wragg D, de Almeida A, Casini A, Leoni S. Unveiling the mechanisms of aquaglyceroporin-3 water and glycerol permeation by metadynamics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31081563 DOI: 10.1002/Chem.201902121 |
0.712 |
|
| 2019 |
Mazzei L, Wenzel MN, Cianci M, Palombo M, Casini A, Ciurli S. Inhibition Mechanism of Urease by Au(III) Compounds Unveiled by X-ray Diffraction Analysis. Acs Medicinal Chemistry Letters. 10: 564-570. PMID 30996797 DOI: 10.1021/Acsmedchemlett.8B00585 |
0.431 |
|
| 2019 |
Wenzel M, Bonsignore R, Thomas S, Bourissou D, Barone G, Casini A. Cyclometalated Au(III) Complexes for Cysteine Arylation in Zinc Finger Protein Domains: Towards Controlled Reductive Elimination. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30990916 DOI: 10.1002/Chem.201901535 |
0.425 |
|
| 2019 |
Pinho JO, Amaral JD, Castro RE, Rodrigues CM, Casini A, Soveral G, Gaspar MM. Copper complex nanoformulations featuring highly promising therapeutic potential in murine melanoma models. Nanomedicine (London, England). PMID 30875274 DOI: 10.2217/Nnm-2018-0388 |
0.337 |
|
| 2019 |
Woods B, Wenzel MN, Williams T, Thomas SR, Jenkins RL, Casini A. -Functionalized Metallacages as Host-Guest Systems for the Anticancer Drug Cisplatin. Frontiers in Chemistry. 7: 68. PMID 30834242 DOI: 10.3389/Fchem.2019.00068 |
0.371 |
|
| 2019 |
Wenzel MN, Mósca AF, Graziani V, Aikman B, Thomas SR, de Almeida A, Platts JA, Re N, Coletti C, Marrone A, Soveral G, Casini A. Insights into the Mechanisms of Aquaporin-3 Inhibition by Gold(III) Complexes: the Importance of Non-Coordinative Adduct Formation. Inorganic Chemistry. PMID 30645101 DOI: 10.1021/Acs.Inorgchem.8B03233 |
0.8 |
|
| 2018 |
Carboni S, Zucca A, Stoccoro S, Maiore L, Arca M, Ortu F, Artner C, Keppler BK, Meier-Menches SM, Casini A, Cinellu MA. New Variations on the Theme of Gold(III) CNN Cyclometalated Complexes as Anticancer Agents: Synthesis and Biological Characterization. Inorganic Chemistry. PMID 30457328 DOI: 10.1021/Acs.Inorgchem.8B02604 |
0.471 |
|
| 2018 |
Mósca AF, de Almeida A, Wragg D, Martins AP, Sabir F, Leoni S, Moura TF, Prista C, Casini A, Soveral G. Molecular Basis of Aquaporin-7 Permeability Regulation by pH. Cells. 7. PMID 30423801 DOI: 10.3390/Cells7110207 |
0.718 |
|
| 2018 |
Han J, Rader A, Reichart F, Aikman B, Wenzel MN, Woods B, Weinmüller M, Ludwig BS, Sturup S, Groothuis GMM, Permentier HP, Bischoff R, Kessler H, Horvatovich P, Casini A. Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin. Bioconjugate Chemistry. PMID 30380298 DOI: 10.1021/Acs.Bioconjchem.8B00682 |
0.372 |
|
| 2018 |
Spreckelmeyer S, van der Zee M, Bertrand B, Bodio E, Stürup S, Casini A. Relevance of Copper and Organic Cation Transporters in the Activity and Transport Mechanisms of an Anticancer Cyclometallated Gold(III) Compound in Comparison to Cisplatin. Frontiers in Chemistry. 6: 377. PMID 30234099 DOI: 10.3389/Fchem.2018.00377 |
0.41 |
|
| 2018 |
Wragg D, de Almeida A, Bonsignore R, Kuehn F, Leoni S, Casini A. On the mechanism of gold NHC compounds binding to DNA G- quadruplexes elucidated by combined metadynamics and biophysical methods. Angewandte Chemie (International Ed. in English). PMID 29972613 DOI: 10.1002/Anie.201805727 |
0.751 |
|
| 2018 |
Aikman B, de Almeida A, Meier-Menches SM, Casini A. Aquaporins in cancer development: opportunities for bioinorganic chemistry to contribute novel chemical probes and therapeutic agents. Metallomics : Integrated Biometal Science. PMID 29766198 DOI: 10.1039/C8Mt00072G |
0.761 |
|
| 2018 |
Boscutti G, Nardon C, Marchiò L, Crisma M, Biondi B, Dalzoppo D, Dalla Via L, Formaggio F, Casini A, Fregona D. Anticancer gold(III) peptidomimetics: from synthesis to in vitro and ex vivo biological evaluation. Chemmedchem. PMID 29570944 DOI: 10.1002/Cmdc.201800098 |
0.404 |
|
| 2018 |
Casini A, Sun RW, Ott I. Medicinal Chemistry of Gold Anticancer Metallodrugs. Metal Ions in Life Sciences. 18. PMID 29394026 DOI: 10.1515/9783110470734-013 |
0.351 |
|
| 2018 |
Wenzel MN, Meier-Menches SM, Williams TL, Rämisch E, Barone G, Casini A. Selective targeting of PARP-1 zinc finger recognition domains with Au(iii) organometallics. Chemical Communications (Cambridge, England). PMID 29292454 DOI: 10.1039/C7Cc08406D |
0.401 |
|
| 2017 |
Casini A, Woods B, Wenzel M. The Promise of Self-Assembled 3D Supramolecular Coordination Complexes for Biomedical Applications. Inorganic Chemistry. 56: 14715-14729. PMID 29172467 DOI: 10.1021/Acs.Inorgchem.7B02599 |
0.34 |
|
| 2017 |
Spreckelmeyer S, Estrada-Ortiz N, Prins GGH, van der Zee M, Gammelgaard B, Stürup S, de Graaf IAM, Groothuis GMM, Casini A. On the toxicity and transport mechanisms of cisplatin in kidney tissues in comparison to a gold-based cytotoxic agent. Metallomics : Integrated Biometal Science. PMID 29104982 DOI: 10.1039/C7Mt00271H |
0.386 |
|
| 2017 |
Karaca Ö, Scalcon V, Meier-Menches SM, Bonsignore R, Brouwer JMJL, Tonolo F, Folda A, Rigobello MP, Kühn FE, Casini A. Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric Approaches. Inorganic Chemistry. PMID 29095609 DOI: 10.1021/Acs.Inorgchem.7B02345 |
0.511 |
|
| 2017 |
Boorsma CE, van der Veen TA, Putri KSS, de Almeida A, Draijer C, Mauad T, Fejer G, Brandsma CA, van den Berge M, Bossé Y, Sin D, Hao K, Reithmeier A, Andersson G, Olinga P, ... ... Casini A, et al. A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages. Scientific Reports. 7: 12570. PMID 28974738 DOI: 10.1038/S41598-017-12623-W |
0.719 |
|
| 2017 |
Jürgens S, Scalcon V, Estrada-Ortiz N, Folda A, Tonolo F, Jandl C, Browne DL, Rigobello MP, Kühn FE, Casini A. Exploring the C^N^C theme: Synthesis and biological properties of tridentate cyclometalated gold(III) complexes. Bioorganic & Medicinal Chemistry. PMID 28823538 DOI: 10.1016/J.Bmc.2017.08.001 |
0.398 |
|
| 2017 |
Graziani V, Marrone A, Re N, Coletti C, Platts JA, Casini A. A multilevel theoretical study to disclose the binding mechanisms of gold(III) bipyridyl compounds as selective aquaglyceroporin inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28776779 DOI: 10.1002/Chem.201703092 |
0.44 |
|
| 2017 |
Casini A, Estrada-Ortiz N, Gabbiani C, Guarra F, Groothuis G, de Graaf I, de Jager M, Marchetti L. Anticancer gold N-heterocyclic carbene complexes: a comparative in vitro and ex vivo study. Chemmedchem. PMID 28741878 DOI: 10.1002/Cmdc.201700316 |
0.444 |
|
| 2017 |
Karaca Ö, Meier-Menches SM, Casini A, Kühn FE. On the binding modes of metal NHC complexes with DNA secondary structures: implications for therapy and imaging. Chemical Communications (Cambridge, England). PMID 28653066 DOI: 10.1039/C7Cc03074F |
0.397 |
|
| 2017 |
Jürgens S, Casini A. Mechanistic Insights into Gold Organometallic Compounds and their Biomedical Applications. Chimia. 71: 308. PMID 28576158 DOI: 10.2533/Chimia.2017.308 |
0.363 |
|
| 2017 |
Jürgens S, Kühn FE, Casini A. Cyclometalated complexes of platinum and gold with biological properties: state-of-the-art and future perspectives. Current Medicinal Chemistry. PMID 28554319 DOI: 10.2174/0929867324666170529125229 |
0.441 |
|
| 2017 |
Jürgens S, Casini A. Mechanistic Insights into Gold Organometallic Compounds and their Biomedical Applications. Chimia. 71: 92-101. PMID 28351454 DOI: 10.2533/Chimia.2017.92 |
0.425 |
|
| 2017 |
de Almeida A, Mósca AF, Wragg D, Wenzel M, Kavanagh P, Barone G, Leoni S, Soveral G, Casini A. The mechanism of aquaporin inhibition by gold compounds elucidated by biophysical and computational methods. Chemical Communications (Cambridge, England). PMID 28304043 DOI: 10.1039/C7Cc00318H |
0.77 |
|
| 2017 |
Wenzel M, Casini A. Mass spectrometry as a powerful tool to study therapeutic metallodrugs speciation mechanisms: Current frontiers and perspectives Coordination Chemistry Reviews. 352: 432-460. DOI: 10.1016/J.Ccr.2017.02.012 |
0.403 |
|
| 2017 |
Medrano MA, Morais M, Ferreira VFC, Correia JDG, Paulo A, Santos I, Navarro-Ranninger C, Valdes AA, Casini A, Mendes F, Quiroga AG. Nonconventionaltrans-Platinum Complexes Functionalized with RDG Peptides: Chemical and Cytototoxicity Studies European Journal of Inorganic Chemistry. 2017: 1835-1840. DOI: 10.1002/Ejic.201700072 |
0.338 |
|
| 2016 |
Muenzner JK, Biersack B, Albrecht A, Rehm T, Lacher U, Milius W, Casini A, Zhang JJ, Ott I, Brabec V, Stuchlikova O, Andronache IC, Schuppan D, Kaps L, Schobert R. Ferrocenyl-Coupled N-Heterocyclic Carbene Complexes of Gold(I): a Successful Approach to Multinuclear Anticancer Drugs. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27761940 DOI: 10.1002/Chem.201604246 |
0.389 |
|
| 2016 |
Khan RA, de Almeida A, Al-Farhan K, Alsalme A, Casini A, Ghazzali M, Reedijk J. Transition-metal norharmane compounds as possible cytotoxic agents: New insights based on a coordination chemistry perspective. Journal of Inorganic Biochemistry. PMID 27453532 DOI: 10.1016/J.Jinorgbio.2016.07.001 |
0.77 |
|
| 2016 |
Schmidt A, Hollering M, Han J, Casini A, Kühn FE. Self-assembly of highly luminescent heteronuclear coordination cages. Dalton Transactions (Cambridge, England : 2003). PMID 27436541 DOI: 10.1039/C6Dt02708C |
0.364 |
|
| 2016 |
Nave M, Castro RE, Rodrigues CM, Casini A, Soveral G, Gaspar MM. Nanoformulations of a potent copper-based aquaporin inhibitor with cytotoxic effect against cancer cells. Nanomedicine (London, England). 11: 1817-30. PMID 27388811 DOI: 10.2217/Nnm-2016-0086 |
0.314 |
|
| 2016 |
Gabbiani C, Pratesi A, Marchetti L, Casini A, Leoni P, Pillozzi S, Crociani O, Bartoli G, Messori L. Potent in vitro antiproliferative properties for a triplatinum cluster toward triple negative breast cancer cells. Journal of Inorganic Biochemistry. PMID 27381671 DOI: 10.1016/J.Jinorgbio.2016.06.024 |
0.56 |
|
| 2016 |
Schmidt A, Hollering M, Drees M, Casini A, Kühn FE. Supramolecular exo-functionalized palladium cages: fluorescent properties and biological activity. Dalton Transactions (Cambridge, England : 2003). PMID 27126799 DOI: 10.1039/C6Dt00654J |
0.352 |
|
| 2016 |
de Almeida A, Martins AP, Mósca AF, Wijma HJ, Prista C, Soveral G, Casini A. Exploring the gating mechanisms of aquaporin-3: new clues for the design of inhibitors? Molecular Biosystems. 12: 1564-73. PMID 26960817 DOI: 10.1039/C6Mb00013D |
0.732 |
|
| 2016 |
Bazzicalupi C, Ferraroni M, Papi F, Massai L, Bertrand B, Messori L, Gratteri P, Casini A. Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation. Angewandte Chemie (International Ed. in English). PMID 26929051 DOI: 10.1002/Anie.201511999 |
0.582 |
|
| 2016 |
Wenzel M, de Almeida A, Bigaeva E, Kavanagh P, Picquet M, Le Gendre P, Bodio E, Casini A. New Luminescent Polynuclear Metal Complexes with Anticancer Properties: Toward Structure-Activity Relationships. Inorganic Chemistry. PMID 26867101 DOI: 10.1021/Acs.Inorgchem.5B02910 |
0.783 |
|
| 2016 |
Meier SM, Gerner C, Keppler BK, Cinellu MA, Casini A. Mass Spectrometry Uncovers Molecular Reactivities of Coordination and Organometallic Gold(III) Drug Candidates in Competitive Experiments That Correlate with Their Biological Effects. Inorganic Chemistry. 55: 4248-59. PMID 26866307 DOI: 10.1021/Acs.Inorgchem.5B03000 |
0.428 |
|
| 2016 |
Spinello A, de Almeida A, Casini A, Barone G. The inhibition of glycerol permeation through aquaglyceroporin-3 induced by mercury(II): A molecular dynamics study. Journal of Inorganic Biochemistry. 160: 78-84. PMID 26766001 DOI: 10.1016/J.Jinorgbio.2015.11.027 |
0.748 |
|
| 2016 |
Schmidt A, Molano V, Hollering M, Pöthig A, Casini A, Kühn FE. Evaluation of New Palladium Cages as Potential Delivery Systems for the Anticancer Drug Cisplatin. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26756963 DOI: 10.1002/Chem.201504930 |
0.314 |
|
| 2016 |
Citta A, Scalcon V, Göbel P, Bertrand B, Wenzel M, Folda A, Rigobello MP, Meggers E, Casini A. Toward anticancer gold-based compounds targeting PARP-1: a new case study Rsc Advances. 6: 79147-79152. DOI: 10.1039/C6Ra11606J |
0.484 |
|
| 2016 |
Tsitsa I, Tarushi A, Doukoume P, Perdih F, de Almeida A, Papadopoulos A, Kalogiannis S, Casini A, Turel I, Psomas G. Structure and biological activities of metal complexes of flumequine Rsc Advances. 6: 19555-19570. DOI: 10.1039/C5Ra25776J |
0.391 |
|
| 2016 |
Hahn EM, Estrada-Ortiz N, Han J, Ferreira VFC, Kapp TG, Correia JDG, Casini A, Kühn FE. Functionalization of Ruthenium(II) Terpyridine Complexes with Cyclic RGD Peptides To Target Integrin Receptors in Cancer Cells European Journal of Inorganic Chemistry. 2017: 1667-1672. DOI: 10.1002/Ejic.201601094 |
0.374 |
|
| 2016 |
Kaiser F, Schmidt A, Heydenreuter W, Altmann PJ, Casini A, Sieber SA, Kühn FE. Self-Assembled Palladium and Platinum Coordination Cages: Photophysical Studies and Anticancer Activity European Journal of Inorganic Chemistry. 2016: 5189-5196. DOI: 10.1002/Ejic.201600811 |
0.368 |
|
| 2015 |
Folda A, Scalcon V, Ghazzali M, Jaafar MH, Khan RA, Casini A, Citta A, Bindoli A, Rigobello MP, Al-Farhan K, Alsalme A, Reedijk J. Insights into the strong in-vitro anticancer effects for bis(triphenylphosphane)iminium compounds having perchlorate, tetrafluoridoborate and bis(chlorido)argentate anions. Journal of Inorganic Biochemistry. PMID 26384162 DOI: 10.1016/J.Jinorgbio.2015.08.030 |
0.439 |
|
| 2015 |
Rajaratnam R, Martin EK, Dörr M, Harms K, Casini A, Meggers E. Correlation between the Stereochemistry and Bioactivity in Octahedral Rhodium Prolinato Complexes. Inorganic Chemistry. 54: 8111-20. PMID 26251218 DOI: 10.1021/Acs.Inorgchem.5B01349 |
0.416 |
|
| 2015 |
Bertrand B, Citta A, Franken IL, Picquet M, Folda A, Scalcon V, Rigobello MP, Le Gendre P, Casini A, Bodio E. Gold(I) NHC-based homo- and heterobimetallic complexes: synthesis, characterization and evaluation as potential anticancer agents. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 20: 1005-20. PMID 26202908 DOI: 10.1007/S00775-015-1283-1 |
0.467 |
|
| 2015 |
Muenzner JK, Rehm T, Biersack B, Casini A, de Graaf IA, Worawutputtapong P, Noor A, Kempe R, Brabec V, Kasparkova J, Schobert R. Adjusting the DNA Interaction and Anticancer Activity of Pt(II) N-Heterocyclic Carbene Complexes by Steric Shielding of the Trans Leaving Group. Journal of Medicinal Chemistry. 58: 6283-92. PMID 26182125 DOI: 10.1021/Acs.Jmedchem.5B00896 |
0.388 |
|
| 2015 |
Bertrand B, Spreckelmeyer S, Bodio E, Cocco F, Picquet M, Richard P, Le Gendre P, Orvig C, Cinellu MA, Casini A. Exploring the potential of gold(iii) cyclometallated compounds as cytotoxic agents: variations on the C^N theme. Dalton Transactions (Cambridge, England : 2003). 44: 11911-8. PMID 26060937 DOI: 10.1039/C5Dt01023C |
0.439 |
|
| 2015 |
Jacques A, Lebrun C, Casini A, Kieffer I, Proux O, Latour JM, Sénèque O. Reactivity of Cys4 zinc finger domains with gold(III) complexes: Insights into the formation of "gold fingers" Inorganic Chemistry. 54: 4104-4113. PMID 25839236 DOI: 10.1021/Acs.Inorgchem.5B00360 |
0.428 |
|
| 2015 |
Laskay ÜA, Garino C, Tsybin YO, Salassa L, Casini A. Gold finger formation studied by high-resolution mass spectrometry and in silico methods. Chemical Communications (Cambridge, England). 51: 1612-5. PMID 25500668 DOI: 10.1039/C4Cc07490D |
0.355 |
|
| 2015 |
Bertrand B, Bodio E, Richard P, Picquet M, Le Gendre P, Casini A. Gold(I) N-heterocyclic carbene complexes with an "activable" ester moiety: Possible biological applications Journal of Organometallic Chemistry. 775: 124-129. DOI: 10.1016/J.Jorganchem.2014.03.020 |
0.46 |
|
| 2014 |
Frik M, Jiménez J, Vasilevski V, Carreira M, de Almeida A, Gascón E, Benoit F, Sanaú M, Casini A, Contel M. Luminescent iminophosphorane gold, palladium and platinum complexes as potential anticancer agents. Inorganic Chemistry Frontiers. 1: 231-241. PMID 27660713 DOI: 10.1039/C4Qi00003J |
0.784 |
|
| 2014 |
Spreckelmeyer S, Orvig C, Casini A. Cellular transport mechanisms of cytotoxic metallodrugs: an overview beyond cisplatin. Molecules (Basel, Switzerland). 19: 15584-610. PMID 25268716 DOI: 10.3390/Molecules191015584 |
0.429 |
|
| 2014 |
Wenzel M, Bigaeva E, Richard P, Le Gendre P, Picquet M, Casini A, Bodio E. New heteronuclear gold(I)-platinum(II) complexes with cytotoxic properties: are two metals better than one? Journal of Inorganic Biochemistry. 141: 10-6. PMID 25172993 DOI: 10.1016/J.Jinorgbio.2014.07.011 |
0.494 |
|
| 2014 |
Ahmad Khan R, Al-Farhan K, de Almeida A, Alsalme A, Casini A, Ghazzali M, Reedijk J. Light-stable bis(norharmane)silver(I) compounds: synthesis, characterization and antiproliferative effects in cancer cells. Journal of Inorganic Biochemistry. 140: 1-5. PMID 25042730 DOI: 10.1016/J.Jinorgbio.2014.06.019 |
0.769 |
|
| 2014 |
Madeira A, De Almeida A, De Graaf C, Camps M, Zorzano A, Moura TF, Casini A, Soveral G. A gold coordination compound as a chemical probe to unravel aquaporin-7 function Chembiochem. 15: 1487-1494. PMID 24891084 DOI: 10.1002/Cbic.201402103 |
0.763 |
|
| 2014 |
Rubbiani R, Salassa L, de Almeida A, Casini A, Ott I. Cytotoxic gold(I) N-heterocyclic carbene complexes with phosphane ligands as potent enzyme inhibitors. Chemmedchem. 9: 1205-10. PMID 24677779 DOI: 10.1002/Cmdc.201400056 |
0.78 |
|
| 2014 |
Serna A, Galán-Cobo A, Rodrigues C, Sánchez-Gomar I, Toledo-Aral JJ, Moura TF, Casini A, Soveral G, EchevarrÃa M. Functional inhibition of aquaporin-3 with a gold-based compound induces blockage of cell proliferation. Journal of Cellular Physiology. 229: 1787-801. PMID 24676973 DOI: 10.1002/Jcp.24632 |
0.34 |
|
| 2014 |
De March M, Demitri N, De Zorzi R, Casini A, Gabbiani C, Guerri A, Messori L, Geremia S. Nitrate as a probe of cytochrome c surface: crystallographic identification of crucial "hot spots" for protein-protein recognition. Journal of Inorganic Biochemistry. 135: 58-67. PMID 24662464 DOI: 10.1016/J.Jinorgbio.2014.02.015 |
0.521 |
|
| 2014 |
Bertrand B, Stefan L, Pirrotta M, Monchaud D, Bodio E, Richard P, Le Gendre P, Warmerdam E, de Jager MH, Groothuis GM, Picquet M, Casini A. Caffeine-based gold(I) N-heterocyclic carbenes as possible anticancer agents: synthesis and biological properties. Inorganic Chemistry. 53: 2296-303. PMID 24499428 DOI: 10.1021/Ic403011H |
0.448 |
|
| 2014 |
Bertrand B, Casini A. A golden future in medicinal inorganic chemistry: the promise of anticancer gold organometallic compounds. Dalton Transactions (Cambridge, England : 2003). 43: 4209-19. PMID 24225667 DOI: 10.1039/C3Dt52524D |
0.469 |
|
| 2014 |
de Almeida A, Soveral G, Casini A. Gold compounds as aquaporin inhibitors: new opportunities for therapy and imaging Med. Chem. Commun.. 5: 1444-1453. DOI: 10.1039/C4Md00265B |
0.368 |
|
| 2014 |
Serratice M, Bertrand B, Janssen EFJ, Hemelt E, Zucca A, Cocco F, Cinellu MA, Casini A. Gold(i) compounds with lansoprazole-type ligands: synthesis, characterization and anticancer properties in vitro Med. Chem. Commun.. 5: 1418-1422. DOI: 10.1039/C4Md00241E |
0.408 |
|
| 2014 |
Hahn EM, Casini A, Kühn FE. Re(VII) and Tc(VII) trioxo complexes stabilized by tridentate ligands and their potential use as radiopharmaceuticals Coordination Chemistry Reviews. 276: 97-111. DOI: 10.1016/J.Ccr.2014.05.021 |
0.403 |
|
| 2014 |
Schmidt A, Casini A, Kühn FE. Self-assembled M2L4 coordination cages: Synthesis and potential applications Coordination Chemistry Reviews. 275: 19-36. DOI: 10.1016/J.Ccr.2014.03.037 |
0.344 |
|
| 2014 |
Bertrand B, Almeida Ad, Burgt EPMvd, Picquet M, Citta A, Folda A, Rigobello MP, Gendre PL, Bodio E, Casini A. New Gold(I) Organometallic Compounds with Biological Activity in Cancer Cells (Eur. J. Inorg. Chem. 27/2014) European Journal of Inorganic Chemistry. 2014. DOI: 10.1002/Ejic.201490137 |
0.371 |
|
| 2014 |
Bertrand B, Almeida Ad, Burgt EPMvd, Picquet M, Citta A, Folda A, Rigobello MP, Gendre PL, Bodio E, Casini A. New Gold(I) Organometallic Compounds with Biological Activity in Cancer Cells European Journal of Inorganic Chemistry. 2014: 4532-4536. DOI: 10.1002/Ejic.201402248 |
0.427 |
|
| 2014 |
Rubbiani R, Salassa L, Almeida Ad, Casini A, Ott I. Cover Picture: Cytotoxic Gold(I) N‐heterocyclic Carbene Complexes with Phosphane Ligands as Potent Enzyme Inhibitors (ChemMedChem 6/2014) Chemmedchem. 9: 1085-1085. DOI: 10.1002/Cmdc.201490020 |
0.377 |
|
| 2013 |
Hanif M, Meier SM, Nazarov AA, Risse J, Legin A, Casini A, Jakupec MA, Keppler BK, Hartinger CG. Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes. Frontiers in Chemistry. 1: 27. PMID 24790955 DOI: 10.3389/Fchem.2013.00027 |
0.471 |
|
| 2013 |
Lease N, Vasilevski V, Carreira M, de Almeida A, Sanaú M, Hirva P, Casini A, Contel M. Potential anticancer heterometallic Fe-Au and Fe-Pd agents: initial mechanistic insights. Journal of Medicinal Chemistry. 56: 5806-18. PMID 23786413 DOI: 10.1021/Jm4007615 |
0.758 |
|
| 2013 |
Citta A, Schuh E, Mohr F, Folda A, Massimino ML, Bindoli A, Casini A, Rigobello MP. Fluorescent silver(I) and gold(I)-N-heterocyclic carbene complexes with cytotoxic properties: mechanistic insights. Metallomics : Integrated Biometal Science. 5: 1006-15. PMID 23661165 DOI: 10.1039/C3Mt20260G |
0.392 |
|
| 2013 |
Hartinger CG, Groessl M, Meier SM, Casini A, Dyson PJ. Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs. Chemical Society Reviews. 42: 6186-99. PMID 23660626 DOI: 10.1039/C3Cs35532B |
0.366 |
|
| 2013 |
Martins AP, Ciancetta A, deAlmeida A, Marrone A, Re N, Soveral G, Casini A. Aquaporin inhibition by gold(III) compounds: New insights Chemmedchem. 8: 1086-1092. PMID 23653381 DOI: 10.1002/Cmdc.201300107 |
0.445 |
|
| 2013 |
Tasan S, Zava O, Bertrand B, Bernhard C, Goze C, Picquet M, Le Gendre P, Harvey P, Denat F, Casini A, Bodio E. BODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics. Dalton Transactions (Cambridge, England : 2003). 42: 6102-9. PMID 23232925 DOI: 10.1039/C2Dt32055J |
0.395 |
|
| 2013 |
De Luca A, Hartinger CG, Dyson PJ, Lo Bello M, Casini A. A new target for gold(I) compounds: glutathione-S-transferase inhibition by auranofin. Journal of Inorganic Biochemistry. 119: 38-42. PMID 23183361 DOI: 10.1016/J.Jinorgbio.2012.08.006 |
0.433 |
|
| 2013 |
Guidi F, Modesti A, Landini I, Nobili S, Mini E, Bini L, Puglia M, Casini A, Dyson PJ, Gabbiani C, Messori L. The molecular mechanisms of antimetastatic ruthenium compounds explored through DIGE proteomics. Journal of Inorganic Biochemistry. 118: 94-9. PMID 23142974 DOI: 10.1016/J.Jinorgbio.2012.10.003 |
0.564 |
|
| 2013 |
de Almeida A, Oliveira BL, Correia JD, Soveral G, Casini A. Emerging protein targets for metal-based pharmaceutical agents: An update Coordination Chemistry Reviews. 257: 2689-2704. DOI: 10.1016/J.Ccr.2013.01.031 |
0.411 |
|
| 2012 |
Martins AP, Marrone A, Ciancetta A, Galán Cobo A, EchevarrÃa M, Moura TF, Re N, Casini A, Soveral G. Targeting aquaporin function: potent inhibition of aquaglyceroporin-3 by a gold-based compound. Plos One. 7: e37435. PMID 22624030 DOI: 10.1371/Journal.Pone.0037435 |
0.47 |
|
| 2012 |
Schuh E, Pflüger C, Citta A, Folda A, Rigobello MP, Bindoli A, Casini A, Mohr F. Gold(I) carbene complexes causing thioredoxin 1 and thioredoxin 2 oxidation as potential anticancer agents. Journal of Medicinal Chemistry. 55: 5518-28. PMID 22621714 DOI: 10.1021/Jm300428V |
0.449 |
|
| 2012 |
Casini A. Exploring the mechanisms of metal-based pharmacological agents via an integrated approach. Journal of Inorganic Biochemistry. 109: 97-106. PMID 22342074 DOI: 10.1016/J.Jinorgbio.2011.12.007 |
0.38 |
|
| 2012 |
Serratrice M, Edafe F, Mendes F, Scopelliti R, Zakeeruddin SM, Grätzel M, Santos I, Cinellu MA, Casini A. Cytotoxic gold compounds: synthesis, biological characterization and investigation of their inhibition properties of the zinc finger protein PARP-1. Dalton Transactions (Cambridge, England : 2003). 41: 3287-93. PMID 22289927 DOI: 10.1039/C2Dt11913G |
0.49 |
|
| 2012 |
Komeda S, Casini A. Next-generation anticancer metallodrugs. Current Topics in Medicinal Chemistry. 12: 219-35. PMID 22236158 DOI: 10.2174/156802612799078964 |
0.436 |
|
| 2012 |
Messori L, Cubo L, Gabbiani C, Álvarez-Valdés A, Michelucci E, Pieraccini G, Ríos-Luci C, León LG, Padrón JM, Navarro-Ranninger C, Casini A, Quiroga AG. Reactivity and biological properties of a series of cytotoxic PtI2(amine)2 complexes, either cis or trans configured. Inorganic Chemistry. 51: 1717-26. PMID 22225466 DOI: 10.1021/Ic202036C |
0.602 |
|
| 2012 |
Casini A, Reedijk J. Interactions of anticancer Pt compounds with proteins: An overlooked topic in medicinal inorganic chemistry? Chemical Science. 3: 3135-3144. DOI: 10.1039/C2Sc20627G |
0.416 |
|
| 2011 |
Stepanenko IN, Casini A, Edafe F, Novak MS, Arion VB, Dyson PJ, Jakupec MA, Keppler BK. Conjugation of organoruthenium(II) 3-(1H-benzimidazol-2-yl)pyrazolo[3,4-b]pyridines and indolo[3,2-d]benzazepines to recombinant human serum albumin: a strategy to enhance cytotoxicity in cancer cells. Inorganic Chemistry. 50: 12669-79. PMID 22111668 DOI: 10.1021/Ic201801E |
0.369 |
|
| 2011 |
Casini A, Messori L. Molecular mechanisms and proposed targets for selected anticancer gold compounds. Current Topics in Medicinal Chemistry. 11: 2647-60. PMID 22039866 DOI: 10.2174/156802611798040732 |
0.606 |
|
| 2011 |
Vergara E, Cerrada E, Clavel C, Casini A, Laguna M. Thiolato gold(I) complexes containing water-soluble phosphane ligands: a characterization of their chemical and biological properties. Dalton Transactions (Cambridge, England : 2003). 40: 10927-35. PMID 21904768 DOI: 10.1039/C1Dt10892A |
0.431 |
|
| 2011 |
Gabbiani C, Casini A, Kelter G, Cocco F, Cinellu MA, Fiebig HH, Messori L. Mechanistic studies on two dinuclear organogold(III) compounds showing appreciable antiproliferative properties and a high redox stability. Metallomics : Integrated Biometal Science. 3: 1318-23. PMID 21887452 DOI: 10.1039/C1Mt00113B |
0.585 |
|
| 2011 |
Wenzel M, Bertrand B, Eymin MJ, Comte V, Harvey JA, Richard P, Groessl M, Zava O, Amrouche H, Harvey PD, Le Gendre P, Picquet M, Casini A. Multinuclear cytotoxic metallodrugs: physicochemical characterization and biological properties of novel heteronuclear gold-titanium complexes. Inorganic Chemistry. 50: 9472-80. PMID 21875041 DOI: 10.1021/Ic201155Y |
0.387 |
|
| 2011 |
Nowak-Sliwinska P, van Beijnum JR, Casini A, Nazarov AA, Wagnieres G, van den Bergh H, Dyson PJ, Griffioen AW. Organometallic ruthenium(II) arene compounds with antiangiogenic activity. Journal of Medicinal Chemistry. 54: 3895-902. PMID 21534534 DOI: 10.1021/Jm2002074 |
0.418 |
|
| 2011 |
Mendes F, Groessl M, Nazarov AA, Tsybin YO, Sava G, Santos I, Dyson PJ, Casini A. Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA. Journal of Medicinal Chemistry. 54: 2196-206. PMID 21370912 DOI: 10.1021/Jm2000135 |
0.384 |
|
| 2011 |
Mügge C, Rothenburger C, Beyer A, Görls H, Gabbiani C, Casini A, Michelucci E, Landini I, Nobili S, Mini E, Messori L, Weigand W. Structure, solution chemistry, antiproliferative actions and protein binding properties of non-conventional platinum(II) compounds with sulfur and phosphorus donors. Dalton Transactions (Cambridge, England : 2003). 40: 2006-16. PMID 21212880 DOI: 10.1039/C0Dt00845A |
0.597 |
|
| 2011 |
Marcon G, Casini A, Mura P, Messori L, Bergamo A, Orioli P. Biological Properties of IRIM, the Iridium(III) Analogue of (Imidazolium (Bisimidazole) Tetrachlororuthenate) (ICR). Metal-Based Drugs. 7: 195-200. PMID 18475945 DOI: 10.1155/Mbd.2000.195 |
0.555 |
|
| 2011 |
Ascone I, Messori L, Balerna A, Castellano C, Gabbiani C, Casini A, Marchioni C, Castellano AC. XAS/XRD complementary data on metallodrugs and their proteins complexes Acta Crystallographica Section A. 67: 517-517. DOI: 10.1107/S0108767311086909 |
0.514 |
|
| 2011 |
Gabbiani C, Mastrobuoni G, Sorrentino F, Dani B, Rigobello MP, Bindoli A, Cinellu MA, Pieraccini G, Messori L, Casini A. Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(iii) compounds studied with combined mass spectrometry and biochemical assays Medchemcomm. 2: 50-54. DOI: 10.1039/C0Md00181C |
0.599 |
|
| 2011 |
Snelders DJM, Casini A, Edafe F, Van Koten G, Klein Gebbink RJM, Dyson PJ. Ruthenium(II) arene complexes with oligocationic triarylphosphine ligands: Synthesis, DNA interactions and in vitro properties Journal of Organometallic Chemistry. 696: 1108-1116. DOI: 10.1016/J.Jorganchem.2010.11.025 |
0.415 |
|
| 2011 |
Ang WH, Casini A, Sava G, Dyson PJ. Organometallic ruthenium-based antitumor compounds with novel modes of action Journal of Organometallic Chemistry. 696: 989-998. DOI: 10.1016/J.Jorganchem.2010.11.009 |
0.469 |
|
| 2010 |
Messori L, Casini A, Gabbiani C, Michelucci E, Cubo L, Ríos-Luci C, Padrón JM, Navarro-Ranninger C, Quiroga AG. Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II) Complex. Acs Medicinal Chemistry Letters. 1: 381-5. PMID 24900222 DOI: 10.1021/Ml100081E |
0.576 |
|
| 2010 |
Cinellu MA, Maiore L, Manassero M, Casini A, Arca M, Fiebig HH, Kelter G, Michelucci E, Pieraccini G, Gabbiani C, Messori L. [Au2(phen(2Me))2(μ-O)2](PF6)2, a Novel Dinuclear Gold(III) Complex Showing Excellent Antiproliferative Properties. Acs Medicinal Chemistry Letters. 1: 336-9. PMID 24900215 DOI: 10.1021/Ml100097F |
0.636 |
|
| 2010 |
Messori L, Balerna A, Ascone I, Castellano C, Gabbiani C, Casini A, Marchioni C, Jaouen G, Congiu Castellano A. X-ray absorption spectroscopy studies of the adducts formed between cytotoxic gold compounds and two major serum proteins. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 16: 491-9. PMID 21181484 DOI: 10.1007/S00775-010-0748-5 |
0.553 |
|
| 2010 |
Groessl M, Terenghi M, Casini A, Elviri L, Lobinski R, Dyson PJ. Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS. Journal of Analytical Atomic Spectrometry. 25: 305-313. PMID 21151827 DOI: 10.1039/B922701F |
0.324 |
|
| 2010 |
Casini A, Temperini C, Gabbiani C, Supuran CT, Messori L. The x-ray structure of the adduct between NAMI-A and carbonic anhydrase provides insights into the reactivity of this metallodrug with proteins. Chemmedchem. 5: 1989-94. PMID 20931644 DOI: 10.1002/Cmdc.201000331 |
0.521 |
|
| 2010 |
Pelletier F, Comte V, Massard A, Wenzel M, Toulot S, Richard P, Picquet M, Le Gendre P, Zava O, Edafe F, Casini A, Dyson PJ. Development of bimetallic titanocene-ruthenium-arene complexes as anticancer agents: relationships between structural and biological properties. Journal of Medicinal Chemistry. 53: 6923-33. PMID 20822096 DOI: 10.1021/Jm1004804 |
0.393 |
|
| 2010 |
Cubo L, Groessl M, Dyson PJ, Quiroga AG, Navarro-Ranninger C, Casini A. Proteins as possible targets for cytotoxic trans-platinum(II) complexes with aliphatic amine ligands: Further exceptions to the DNA paradigm. Chemmedchem. 5: 1335-43. PMID 20564276 DOI: 10.1002/Cmdc.201000104 |
0.4 |
|
| 2010 |
Casini A, Edafe F, Erlandsson M, Gonsalvi L, Ciancetta A, Re N, Ienco A, Messori L, Peruzzini M, Dyson PJ. Rationalization of the inhibition activity of structurally related organometallic compounds against the drug target cathepsin B by DFT. Dalton Transactions (Cambridge, England : 2003). 39: 5556-63. PMID 20467693 DOI: 10.1039/C003218B |
0.599 |
|
| 2010 |
Casini A, Diawara MC, Scopelliti R, Zakeeruddin SM, Grätzel M, Dyson PJ. Synthesis, characterisation and biological properties of gold(III) compounds with modified bipyridine and bipyridylamine ligands. Dalton Transactions (Cambridge, England : 2003). 39: 2239-45. PMID 20162197 DOI: 10.1039/B921019A |
0.458 |
|
| 2010 |
Innocenti M, Salvietti E, Guidotti M, Casini A, Bellandi S, Foresti ML, Gabbiani C, Pozzi A, Zatta P, Messori L. Trace copper(II) or zinc(II) ions drastically modify the aggregation behavior of amyloid-beta1-42: an AFM study. Journal of Alzheimer's Disease : Jad. 19: 1323-9. PMID 20061619 DOI: 10.3233/Jad-2010-1338 |
0.476 |
|
| 2010 |
Mura P, Camalli M, Casini A, Gabbiani C, Messori L. Trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2], (PMRu52), a novel ruthenium(II) compound acting as a strong inhibitor of cathepsin B. Journal of Inorganic Biochemistry. 104: 111-7. PMID 19939460 DOI: 10.1016/J.Jinorgbio.2009.10.002 |
0.593 |
|
| 2010 |
Vergara E, Casini A, Sorrentino F, Zava O, Cerrada E, Rigobello MP, Bindoli A, Laguna M, Dyson PJ. Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands. Chemmedchem. 5: 96-102. PMID 19937669 DOI: 10.1002/Cmdc.200900370 |
0.448 |
|
| 2010 |
Nobili S, Mini E, Landini I, Gabbiani C, Casini A, Messori L. Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies. Medicinal Research Reviews. 30: 550-80. PMID 19634148 DOI: 10.1002/Med.20168 |
0.609 |
|
| 2010 |
Vergara E, Cerrada E, Casini A, Zava O, Laguna M, Dyson PJ. Antiproliferative Activity of Gold(I) Alkyne Complexes Containing Water-Soluble Phosphane Ligands Organometallics. 29: 2596-2603. DOI: 10.1021/Om100300A |
0.457 |
|
| 2010 |
Gras M, Therrien B, Süss-Fink G, Casini A, Edafe F, Dyson PJ. Anticancer activity of new organo-ruthenium, rhodium and iridium complexes containing the 2-(pyridine-2-yl)thiazole N,N-chelating ligand Journal of Organometallic Chemistry. 695: 1119-1125. DOI: 10.1016/J.Jorganchem.2010.01.020 |
0.394 |
|
| 2010 |
Casini A, Hartinger CG, Nazarov AA, Dyson PJ. Organometallic Antitumour Agents with Alternative Modes of Action Topics in Organometallic Chemistry. 32: 57-80. DOI: 10.1007/978-3-642-13185-1_3 |
0.351 |
|
| 2010 |
Vergara E, Casini A, Sorrentino F, Zava O, Cerrada E, Rigobello M, Bindoli A, Laguna M, Dyson P. Inside Cover: Anticancer Therapeutics That Target Selenoenzymes: Synthesis, Characterization, inâ
vitro Cytotoxicity, and Thioredoxin Reductase Inhibition of a Series of Gold(I) Complexes Containing Hydrophilic Phosphine Ligands (ChemMedChem 1/2010) Chemmedchem. 5: 2-2. DOI: 10.1002/Cmdc.200990065 |
0.417 |
|
| 2009 |
Casini A, Karotki A, Gabbiani C, Rugi F, Vašák M, Messori L, Dyson PJ. Reactivity of an antimetastatic organometallic ruthenium compound with metallothionein-2: relevance to the mechanism of action. Metallomics : Integrated Biometal Science. 1: 434-41. PMID 21305148 DOI: 10.1039/B909185H |
0.554 |
|
| 2009 |
Cubo L, Casini A, Gabbiani C, Mastrobuoni G, Messori L, Jiménez-Barbero J, Navarro-Ranninger C, Quiroga AG. Solution behaviour and biomolecular interactions of two cytotoxic trans-platinum(II) complexes bearing aliphatic amine ligands Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 9139-9146. PMID 19655350 DOI: 10.1002/Chem.200901090 |
0.574 |
|
| 2009 |
Casini A, Kelter G, Gabbiani C, Cinellu MA, Minghetti G, Fregona D, Fiebig HH, Messori L. Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 14: 1139-49. PMID 19543922 DOI: 10.1007/S00775-009-0558-9 |
0.614 |
|
| 2009 |
Grossi C, Francese S, Casini A, Rosi MC, Luccarini I, Fiorentini A, Gabbiani C, Messori L, Moneti G, Casamenti F. Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 17: 423-40. PMID 19363260 DOI: 10.3233/Jad-2009-1063 |
0.496 |
|
| 2009 |
Casini A, Gabbiani C, Michelucci E, Pieraccini G, Moneti G, Dyson PJ, Messori L. Exploring metallodrug-protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 14: 761-70. PMID 19288144 DOI: 10.1007/S00775-009-0489-5 |
0.567 |
|
| 2009 |
Gabbiani C, Messori L, Cinellu MA, Casini A, Mura P, Sannella AR, Severini C, Majori G, Bilia AR, Vincieri FF. Outstanding plasmodicidal properties within a small panel of metallic compounds: Hints for the development of new metal-based antimalarials. Journal of Inorganic Biochemistry. 103: 310-2. PMID 19027959 DOI: 10.1016/J.Jinorgbio.2008.10.004 |
0.601 |
|
| 2009 |
Bindoli A, Rigobello MP, Scutari G, Gabbiani C, Casini A, Messori L. Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs Coordination Chemistry Reviews. 253: 1692-1707. DOI: 10.1016/J.Ccr.2009.02.026 |
0.609 |
|
| 2008 |
Hartinger CG, Casini A, Duhot C, Tsybin YO, Messori L, Dyson PJ. Stability of an organometallic ruthenium-ubiquitin adduct in the presence of glutathione: relevance to antitumour activity. Journal of Inorganic Biochemistry. 102: 2136-41. PMID 18834634 DOI: 10.1016/J.Jinorgbio.2008.08.002 |
0.566 |
|
| 2008 |
Casini A, Gabbiani C, Sorrentino F, Rigobello MP, Bindoli A, Geldbach TJ, Marrone A, Re N, Hartinger CG, Dyson PJ, Messori L. Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds. Journal of Medicinal Chemistry. 51: 6773-81. PMID 18834187 DOI: 10.1021/Jm8006678 |
0.592 |
|
| 2008 |
Chiellini C, Casini A, Cochet O, Gabbiani C, Ailhaud G, Dani C, Messori L, Amri EZ. The influence of auranofin, a clinically established antiarthritic gold drug, on bone metabolism: analysis of its effects on human multipotent adipose-derived stem cells, taken as a model. Chemistry & Biodiversity. 5: 1513-20. PMID 18729088 DOI: 10.1002/Cbdv.200890140 |
0.495 |
|
| 2008 |
Ascone I, Messori L, Casini A, Gabbiani C, Balerna A, Dell'Unto F, Castellano AC. Exploiting soft and hard X-ray absorption spectroscopy to characterize metallodrug/protein interactions: the binding of [trans-RuCl4(Im)(dimethylsulfoxide)][ImH] (Im = imidazole) to bovine serum albumin. Inorganic Chemistry. 47: 8629-34. PMID 18722420 DOI: 10.1021/Ic8001477 |
0.506 |
|
| 2008 |
Gabbiani C, Casini A, Mastrobuoni G, Kirshenbaum N, Moshel O, Pieraccini G, Moneti G, Messori L, Gibson D. Peculiar mechanistic and structural features of the carboplatin-cytochrome c system revealed by ESI-MS analysis Journal of Biological Inorganic Chemistry. 13: 755-764. PMID 18350322 DOI: 10.1007/S00775-008-0361-Z |
0.533 |
|
| 2008 |
Gabbiani C, Casini A, Messori L, Guerri A, Cinellu MA, Minghetti G, Corsini M, Rosani C, Zanello P, Arca M. Structural characterization, solution studies, and DFT calculations on a series of binuclear gold(III) oxo complexes: relationships to biological properties. Inorganic Chemistry. 47: 2368-79. PMID 18314951 DOI: 10.1021/Ic701254S |
0.557 |
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| 2008 |
Sannella AR, Casini A, Gabbiani C, Messori L, Bilia AR, Vincieri FF, Majori G, Severini C. New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications. Febs Letters. 582: 844-7. PMID 18294965 DOI: 10.1016/J.Febslet.2008.02.028 |
0.537 |
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| 2008 |
Casini A, Guerri A, Gabbiani C, Messori L. Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: new insights from X-ray diffraction and mass spectrometry studies. Journal of Inorganic Biochemistry. 102: 995-1006. PMID 18289690 DOI: 10.1016/J.Jinorgbio.2007.12.022 |
0.557 |
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| 2008 |
Casini A, Hartinger C, Gabbiani C, Mini E, Dyson PJ, Keppler BK, Messori L. Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action. Journal of Inorganic Biochemistry. 102: 564-75. PMID 18177942 DOI: 10.1016/J.Jinorgbio.2007.11.003 |
0.606 |
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| 2008 |
Drago D, Bettella M, Bolognin S, Cendron L, Scancar J, Milacic R, Ricchelli F, Casini A, Messori L, Tognon G, Zatta P. Potential pathogenic role of beta-amyloid(1-42)-aluminum complex in Alzheimer's disease. The International Journal of Biochemistry & Cell Biology. 40: 731-46. PMID 18060826 DOI: 10.1016/J.Biocel.2007.10.014 |
0.468 |
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| 2008 |
Bilia AR, Sannella AR, Vincieri FF, Messori L, Casini A, Gabbiani C, Severini C, Majori G. Antiplasmodial Effects of a few Selected Natural Flavonoids and their Modulation of Artemisinin Activity Natural Product Communications. 3: 1934578X0800301. DOI: 10.1177/1934578X0800301212 |
0.491 |
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| 2008 |
Muniz-Miranda M, Pagliai M, Cardini G, Messori L, Bruni B, Casini A, Vaira MD, Schettino V. A multi-technique approach to predicting the molecular structure of cuprizone in the gas phase and in the crystalline state Crystengcomm. 10: 416-422. DOI: 10.1039/B715131D |
0.495 |
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| 2007 |
Pratesi A, Zanello P, Giorgi G, Messori L, Laschi F, Casini A, Corsini M, Gabbiani C, Orfei M, Rosani C, Ginanneschi M. New copper(II)/cyclic tetrapeptide system that easily oxidizes to copper(III) under atmospheric oxygen. Inorganic Chemistry. 46: 10038-40. PMID 17979273 DOI: 10.1021/Ic701411Y |
0.519 |
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| 2007 |
Mura P, Camalli M, Bindoli A, Sorrentino F, Casini A, Gabbiani C, Corsini M, Zanello P, Rigobello MP, Messori L. Activity of rat cytosolic thioredoxin reductase is strongly decreased by trans-[bis(2-amino-5- methylthiazole)tetrachlororuthenate(III)]: first report of relevant thioredoxin reductase inhibition for a ruthenium compound. Journal of Medicinal Chemistry. 50: 5871-4. PMID 17975904 DOI: 10.1021/Jm0708578 |
0.602 |
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| 2007 |
Casini A, Gabbiani C, Mastrobuoni G, Pellicani RZ, Intini FP, Arnesano F, Natile G, Moneti G, Francese S, Messori L. Insights into the molecular mechanisms of protein platination from a case study: The reaction of anticancer platinum(II) iminoethers with horse heart cytochrome C Biochemistry. 46: 12220-12230. PMID 17924668 DOI: 10.1021/Bi701516Q |
0.527 |
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| 2007 |
Casini A, Mastrobuoni G, Terenghi M, Gabbiani C, Monzani E, Moneti G, Casella L, Messori L. Ruthenium anticancer drugs and proteins: A study of the interactions of the ruthenium(III) complex imidazolium trans-[tetrachloro(dimethyl sulfoxide)(imidazole)ruthenate(III)] with hen egg white lysozyme and horse heart cytochrome c Journal of Biological Inorganic Chemistry. 12: 1107-1117. PMID 17680283 DOI: 10.1007/S00775-007-0280-4 |
0.563 |
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| 2007 |
Messori L, Casini A, Gabbiani C, Sorace L, Muniz-Miranda M, Zatta P. Unravelling the chemical nature of copper cuprizone. Dalton Transactions (Cambridge, England : 2003). 2112-4. PMID 17514330 DOI: 10.1039/B701896G |
0.51 |
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| 2007 |
Casini A, Mastrobuoni G, Ang WH, Gabbiani C, Pieraccini G, Moneti G, Dyson PJ, Messori L. ESI-MS characterisation of protein adducts of anticancer ruthenium(II)-arene PTA (RAPTA) complexes Chemmedchem. 2: 631-635. PMID 17366652 DOI: 10.1002/Cmdc.200600258 |
0.565 |
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| 2007 |
Ciani L, Casini A, Gabbiani C, Ristori S, Messori L, Martini G. DOTAP/DOPE and DC-Chol/DOPE lipoplexes for gene delivery studied by circular dichroism and other biophysical techniques. Biophysical Chemistry. 127: 213-20. PMID 17350156 DOI: 10.1016/J.Bpc.2007.02.003 |
0.493 |
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| 2007 |
Cini R, Defazio S, Tamasi G, Casolaro M, Messori L, Casini A, Morpurgo M, Hursthouse M. fac-{Ru(CO)3}2+-core complexes and design of metal-based drugs. synthesis, structure, and reactivity of Ru-thiazole derivative with serum proteins and absorption-release studies with acryloyl and silica hydrogels as carriers in physiological media. Inorganic Chemistry. 46: 79-92. PMID 17198415 DOI: 10.1021/Ic060755S |
0.585 |
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| 2007 |
Casini A, Mastrobuoni G, Temperini C, Gabbiani C, Francese S, Moneti G, Supuran CT, Scozzafava A, Messori L. ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme Chemical Communications. 156-158. PMID 17180231 DOI: 10.1039/B611122J |
0.507 |
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| 2007 |
Sannella AR, Messori L, Casini A, Francesco Vincieri F, Bilia AR, Majori G, Severini C. Antimalarial properties of green tea. Biochemical and Biophysical Research Communications. 353: 177-81. PMID 17174271 DOI: 10.1016/J.Bbrc.2006.12.005 |
0.503 |
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| 2007 |
Sannella A, Messori L, Casini A, Vincieri F, Maiori G, Severini C, Bilia A. Modulation of the in vitro antimalarial effects of artemisinin by selected flavonoids and by reducing agents Planta Medica. 73. DOI: 10.1055/S-2007-986916 |
0.496 |
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| 2007 |
Hartinger CG, Ang WH, Casini A, Messori L, Keppler BK, Dyson PJ. Mass spectrometric analysis of ubiquitin–platinum interactions of leading anticancer drugs: MALDI versus ESI Journal of Analytical Atomic Spectrometry. 22: 960-967. DOI: 10.1039/B703350H |
0.538 |
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| 2007 |
Gabbiani C, Casini A, Messori L. Gold(III) compounds as anticancer drugs Gold Bulletin. 40: 73-81. DOI: 10.1007/Bf03215296 |
0.628 |
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| 2006 |
Casini A, Cinellu MA, Minghetti G, Gabbiani C, Coronnello M, Mini E, Messori L. Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands. Journal of Medicinal Chemistry. 49: 5524-31. PMID 16942025 DOI: 10.1021/Jm060436A |
0.61 |
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| 2006 |
Casini A, Gabbiani C, Mastrobuoni G, Messori L, Moneti G, Pieraccini G. Exploring metallodrug-protein interactions by ESI mass spectrometry: the reaction of anticancer platinum drugs with horse heart cytochrome c Chemmedchem. 1: 413-417. PMID 16892376 DOI: 10.1002/Cmdc.200500079 |
0.495 |
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| 2006 |
Calderone V, Casini A, Mangani S, Messori L, Orioli PL. Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase. Angewandte Chemie (International Ed. in English). 45: 1267-9. PMID 16416478 DOI: 10.1002/Anie.200502599 |
0.507 |
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| 2006 |
Messori L, Gabbiani C, Casini A, Siragusa M, Vincieri FF, Bilia AR. The reaction of artemisinins with hemoglobin: a unified picture. Bioorganic & Medicinal Chemistry. 14: 2972-7. PMID 16412643 DOI: 10.1016/J.Bmc.2005.12.038 |
0.504 |
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| 2005 |
Mincione F, Starnotti M, Masini E, Bacciottini L, Scrivanti C, Casini A, Vullo D, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma. Bioorganic & Medicinal Chemistry Letters. 15: 3821-7. PMID 16039853 DOI: 10.1016/J.Bmcl.2005.06.054 |
0.303 |
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| 2005 |
De Simone G, Di Fiore A, Menchise V, Pedone C, Antel J, Casini A, Scozzafava A, Wurl M, Supuran CT. Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry Letters. 15: 2315-20. PMID 15837316 DOI: 10.1016/J.Bmcl.2005.03.032 |
0.34 |
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| 2005 |
Di Fiore A, De Simone G, Menchise V, Pedone C, Casini A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II. Bioorganic & Medicinal Chemistry Letters. 15: 1937-42. PMID 15780637 DOI: 10.1016/J.Bmcl.2005.01.086 |
0.352 |
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| 2005 |
Winum JY, Dogné JM, Casini A, de Leval X, Montero JL, Scozzafava A, Vullo D, Innocenti A, Supuran CT. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/membrane-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating hydrazino moieties. Journal of Medicinal Chemistry. 48: 2121-5. PMID 15771455 DOI: 10.1021/Jm0494826 |
0.32 |
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| 2004 |
Zimmerman S, Innocenti A, Casini A, Ferry JG, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides. Bioorganic & Medicinal Chemistry Letters. 14: 6001-6. PMID 15546717 DOI: 10.1016/J.Bmcl.2004.09.085 |
0.317 |
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| 2004 |
Bonnac L, Innocenti A, Winum JY, Casini A, Montero JL, Scozzafava A, Barragan V, Supuran CT. Carbonic anhydrase inhibitors: aliphatic N-phosphorylated sulfamates--a novel zinc-anchoring group leading to nanomolar inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 19: 275-8. PMID 15500000 DOI: 10.1080/14756360410001689522 |
0.347 |
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| 2004 |
Galli A, Ceni E, Crabb DW, Mello T, Salzano R, Grappone C, Milani S, Surrenti E, Surrenti C, Casini A. Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms. Gut. 53: 1688-97. PMID 15479693 DOI: 10.1136/Gut.2003.031997 |
0.32 |
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| 2004 |
Innocenti A, Casini A, Alcaro MC, Papini AM, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: the first on-resin screening of a 4-sulfamoylphenylthiourea library. Journal of Medicinal Chemistry. 47: 5224-9. PMID 15456265 DOI: 10.1021/Jm049692I |
0.306 |
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| 2004 |
Supuran CT, Vullo D, Manole G, Casini A, Scozzafava A. Designing of novel carbonic anhydrase inhibitors and activators. Current Medicinal Chemistry. Cardiovascular and Hematological Agents. 2: 49-68. PMID 15328829 DOI: 10.2174/1568016043477305 |
0.3 |
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| 2004 |
Supuran CT, Casini A, Mastrolorenzo A, Scozzafava A. COX-2 selective inhibitors, carbonic anhydrase inhibition and anticancer properties of sulfonamides belonging to this class of pharmacological agents. Mini Reviews in Medicinal Chemistry. 4: 625-32. PMID 15279596 DOI: 10.2174/1389557043403792 |
0.337 |
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| 2004 |
Lehtonen JM, Parkkila S, Vullo D, Casini A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design. Bioorganic & Medicinal Chemistry Letters. 14: 3757-62. PMID 15203157 DOI: 10.1016/J.Bmcl.2004.04.106 |
0.326 |
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| 2004 |
de Leval X, Ilies M, Casini A, Dogné JM, Scozzafava A, Masini E, Mincione F, Starnotti M, Supuran CT. Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity. Journal of Medicinal Chemistry. 47: 2796-804. PMID 15139757 DOI: 10.1021/Jm031116J |
0.349 |
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| 2004 |
Dogné JM, de Leval X, Hanson J, Frederich M, Lambermont B, Ghuysen A, Casini A, Masereel B, Ruan KH, Pirotte B, Kolh P. New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators. Current Medicinal Chemistry. 11: 1223-41. PMID 15134516 DOI: 10.2174/0929867043365260 |
0.314 |
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| 2004 |
Abbate F, Casini A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide. Bioorganic & Medicinal Chemistry Letters. 14: 2357-2361. PMID 15081040 DOI: 10.1016/J.Bmcl.2004.01.096 |
0.356 |
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| 2004 |
Weber A, Casini A, Heine A, Kuhn D, Supuran CT, Scozzafava aA, Klebe G. Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition. Journal of Medicinal Chemistry. 47: 550-557. PMID 14736236 DOI: 10.1021/Jm030912M |
0.33 |
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| 2004 |
Abbate F, Coetzee A, Casini A, Ciattini S, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride. Bioorganic & Medicinal Chemistry Letters. 14: 337-341. PMID 14698154 DOI: 10.1016/J.Bmcl.2003.11.014 |
0.393 |
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| 2004 |
Abbate F, Winum JY, Potter BV, Casini A, Montero JL, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase. Bioorganic & Medicinal Chemistry Letters. 14: 231-4. PMID 14684333 DOI: 10.1016/J.Bmcl.2003.09.064 |
0.352 |
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| 2004 |
Abbate F, Casini A, Owa T, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Bioorganic & Medicinal Chemistry Letters. 14: 217-23. PMID 14684331 DOI: 10.1016/J.Bmcl.2003.09.062 |
0.362 |
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| 2004 |
Abbate F, Casini A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the perfluorobenzoyl analogue of methazolamide. Implications for the drug design of fluorinated inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 18: 303-8. PMID 14567544 DOI: 10.1080/1475636031000119337 |
0.376 |
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| 2003 |
Winum †J, Vullo D, Casini A, Montero †J, Scozzafava aA, Supuran CT. Carbonic Anhydrase Inhibitors: Inhibition of Transmembrane, Tumor-Associated Isozyme IX, and Cytosolic Isozymes I and II with Aliphatic Sulfamates Journal of Medicinal Chemistry. 46: 5471-5477. PMID 14640555 DOI: 10.1021/Jm030911U |
0.308 |
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| 2003 |
Casini A, Scozzafava A, Mincione F, Menabuoni L, Starnotti M, Supuran CT. Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide. Bioorganic & Medicinal Chemistry Letters. 13: 2867-2873. PMID 14611846 DOI: 10.1016/S0960-894X(03)00580-8 |
0.32 |
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| 2003 |
Casini A, Caccia S, Scozzafava A, Supuran CT. Carbonic anhydrase activators. The selective serotonin reuptake inhibitors fluoxetine, sertraline and citalopram are strong activators of isozymes I and II. Bioorganic & Medicinal Chemistry Letters. 13: 2765-2768. PMID 12873510 DOI: 10.1016/S0960-894X(03)00507-9 |
0.317 |
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| 2003 |
Casini A, Abbate F, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a bis-sulfonamide-two heads are better than one? Bioorganic & Medicinal Chemistry Letters. 13: 2759-2763. PMID 12873509 DOI: 10.1016/S0960-894X(03)00508-0 |
0.338 |
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| 2003 |
Supuran CT, Casini A, Scozzafava A. Protease inhibitors of the sulfonamide type: Anticancer, antiinflammatory, and antiviral agents Medicinal Research Reviews. 23: 535-558. PMID 12789686 DOI: 10.1002/Med.10047 |
0.354 |
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| 2003 |
Winum †J, Vullo D, Casini A, Montero †J, Scozzafava aA, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors. Journal of Medicinal Chemistry. 46: 2197-2204. PMID 12747791 DOI: 10.1021/Jm021124K |
0.305 |
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| 2003 |
Casini A, Antel J, Abbate F, Scozzafava A, David S, Waldeck H, Schäfer S, Supuran CT. Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV. Bioorganic & Medicinal Chemistry Letters. 13: 841-5. PMID 12617904 DOI: 10.1016/S0960-894X(03)00029-5 |
0.379 |
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| 2003 |
Casini A, Winum J, Montero J, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: inhibition of cytosolic isozymes I and II with sulfamide derivatives. Bioorganic & Medicinal Chemistry Letters. 13: 837-840. PMID 12617903 DOI: 10.1016/S0960-894X(03)00028-3 |
0.356 |
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| 2003 |
Maestrelli F, Mura P, Casini A, Mincione F, Scozzafava A, Supuran CT. Cyclodextrin complexes of sulfonamide carbonic anhydrase inhibitors as long-lasting topically acting antiglaucoma agents. Journal of Pharmaceutical Sciences. 91: 2211-9. PMID 12226848 DOI: 10.1002/Jps.10215 |
0.322 |
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| 2002 |
Casini A, Scozzafava A, Supuran CT. Cysteine-modifying agents: a possible approach for effective anticancer and antiviral drugs. Environmental Health Perspectives. 110: 801-806. PMID 12426135 DOI: 10.1289/Ehp.02110S5801 |
0.339 |
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| 2002 |
Casini A, Mincione F, Vullo D, Menabuoni L, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors with strong topical antiglaucoma properties incorporating a 4-(2-aminopyrimidin-4-yl-amino)-benzenesulfonamide scaffold. Journal of Enzyme Inhibition and Medicinal Chemistry. 17: 9-18. PMID 12365464 DOI: 10.1080/14756360290018602 |
0.303 |
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| 2002 |
casini A, Scozzafava A, Mastrolorenzo A, Supuran CT. Sulfonamides and sulfonylated derivatives as anticancer agents. Current Cancer Drug Targets. 2: 55-75. PMID 12188921 DOI: 10.2174/1568009023334060 |
0.38 |
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| 2002 |
Scozzafava A, Casini A, Supuran CT. Targeting cysteine residues of biomolecules: new approaches for the design of antiviral and anticancer drugs. Current Medicinal Chemistry. 9: 1167-1185. PMID 12052170 DOI: 10.2174/0929867023370077 |
0.339 |
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| 2002 |
Casini A, Scozzafava A, Supuran CT. Sulfonamide derivatives with protease inhibitory action as anticancer, anti-inflammatory and antiviral agents Expert Opinion On Therapeutic Patents. 12: 1307-1327. DOI: 10.1517/13543776.12.9.1307 |
0.332 |
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| 2001 |
Casini A, Messori L, Orioli P, Gielen M, Kemmer M, Willem R. Interactions of two cytotoxic organotin(IV) compounds with calf thymus DNA. Journal of Inorganic Biochemistry. 85: 297-300. PMID 11551387 DOI: 10.1016/S0162-0134(01)00215-X |
0.553 |
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| 2001 |
Mincione F, Starnotti M, Menabuoni L, Scozzafava A, Casini A, Supuran CT. Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties Bioorganic & Medicinal Chemistry Letters. 11: 1787-1791. PMID 11425561 DOI: 10.1016/S0960-894X(01)00303-1 |
0.312 |
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| 2001 |
Casini A, Mincione F, Ilies MA, Menabuoni L, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: synthesis and inhibition against isozymes I, II and IV of topically acting antiglaucoma sulfonamides incorporating cis-5-norbornene-endo-3-carboxy-2-carboxamido moieties. Journal of Enzyme Inhibition. 16: 113-23. PMID 11342280 DOI: 10.1080/14756360109162361 |
0.354 |
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| 2001 |
Mura P, Casini A, Marcon G, Messori L. Synthesis, molecular structure and solution chemistry of the iridium(III) complex imidazolium [trans(bisimidazole)tetrachloro iridate(III)] (IRIM) Inorganica Chimica Acta. 312: 74-80. DOI: 10.1016/S0020-1693(00)00330-3 |
0.562 |
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| 2000 |
Casini A, Scozzafava A, Mincione F, Menabuoni L, Ilies MA, Supuran CT. Carbonic anhydrase inhibitors: water-soluble 4-sulfamoylphenylthioureas as topical intraocular pressure-lowering agents with long-lasting effects. Journal of Medicinal Chemistry. 43: 4884-92. PMID 11123998 DOI: 10.1021/Jm001051+ |
0.328 |
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| 2000 |
Ilies M, Supuran CT, Scozzafava A, Casini A, Mincione F, Menabuoni L, Caproiu MT, Maganu M, Banciu MD. Carbonic anhydrase inhibitors: sulfonamides incorporating furan-, thiophene- and pyrrole-carboxamido groups possess strong topical intraocular pressure lowering properties as aqueous suspensions. Bioorganic & Medicinal Chemistry. 8: 2145-2155. PMID 11003159 DOI: 10.1016/S0968-0896(00)00143-7 |
0.362 |
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| 2000 |
Gallori E, Vettori C, Alessio E, Vilchez FG, Vilaplana R, Orioli P, Casini A, Messori L. DNA as a Possible Target for Antitumor Ruthenium(III) Complexes: A Spectroscopic and Molecular Biology Study of the Interactions of Two Representative Antineoplastic Ruthenium(III) Complexes with DNA Archives of Biochemistry and Biophysics. 376: 156-162. PMID 10729201 DOI: 10.1006/Abbi.1999.1654 |
0.556 |
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| 2000 |
Ottaviani MF, Furini F, Casini A, Turro NJ, Jockusch S, Tomalia DA, Messori L. Formation of supramolecular structures between DNA and starburst dendrimers studied by EPR, CD, UV, and melting profiles Macromolecules. 33: 7842-7851. DOI: 10.1021/Ma000877I |
0.504 |
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| 2000 |
Messori L, Casini A, Vullo D, Haroutiunian S, Dalian E, Orioli P. Effects of two representative antitumor ruthenium(III) complexes on thermal denaturation profiles of DNA Inorganica Chimica Acta. 303: 283-286. DOI: 10.1016/S0020-1693(99)00528-9 |
0.546 |
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