Eric Meggers - Publications

Affiliations: 
2002-2007 Department of Chemistry University of Pennsylvania, Philadelphia, PA, United States 
 2007- Department of Chemistry University of Marburg, Marburg, Hessen, Germany 
Area:
Organic Chemistry, Inorganic Chemistry, Chemical Biology, Catalysis
Website:
https://www.uni-marburg.de/fb15/ag-meggers

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhang C, Chen S, Ye CX, Harms K, Zhang L, Houk KN, Meggers E. Asymmetric Photocatalysis by Intramolecular Hydrogen-Atom Transfer in Photoexcited Catalyst-Substrate Complex. Angewandte Chemie (International Ed. in English). PMID 31469211 DOI: 10.1002/anie.201905647  0.92
2019 Qin J, Zhou Z, Cui T, Hemming M, Meggers E. Enantioselective intramolecular C-H amination of aliphatic azides by dual ruthenium and phosphine catalysis. Chemical Science. 10: 3202-3207. PMID 30996902 DOI: 10.1039/c9sc00054b  1
2019 Huang X, Meggers E. Asymmetric Photocatalysis with Bis-cyclometalated Rhodium Complexes. Accounts of Chemical Research. PMID 30840435 DOI: 10.1021/acs.accounts.9b00028  0.56
2019 Hong Y, Jarrige L, Harms K, Meggers E. Chiral-at-Iron Catalyst: Expanding the Chemical Space for Asymmetric Earth-Abundant Metal Catalysis. Journal of the American Chemical Society. PMID 30839201 DOI: 10.1021/jacs.9b01352  0.92
2018 Zhou Z, Chen S, Qin J, Nie X, Zheng X, Harms K, Riedel R, Houk KN, Meggers E. Catalytic Enantioselective Intramolecular C(sp3)-H Amination of 2-Azidoacetamides. Angewandte Chemie (International Ed. in English). PMID 30475437 DOI: 10.1002/anie.201811927  1
2018 Qin J, Larionov VA, Harms K, Meggers E. Kinetic Resolution of Epoxides with CO2 Catalyzed by a Chiral-at-Iridium Complex. Chemsuschem. PMID 30324685 DOI: 10.1002/cssc.201802049  0.92
2018 de Assis FF, Huang X, Akiyama M, Pilli RA, Meggers E. Visible-Light-Activated Catalytic Enantioselective β-Alkylation of α,β-Unsaturated 2-Acyl Imidazoles Using Hantzsch Esters as Radical Reservoirs. The Journal of Organic Chemistry. PMID 30028138 DOI: 10.1021/acs.joc.8b01588  0.56
2018 Ma J, Lin J, Zhao L, Harms K, Marsch M, Xie X, Meggers E. Synthesis of beta-Substituted gamma-Aminobutyric Acid Derivatives via Enantioselective Photoredox Catalysis. Angewandte Chemie (International Ed. in English). PMID 29714818 DOI: 10.1002/anie.201804040  0.92
2018 Hu N, Jung H, Zheng Y, Lee J, Zhang L, Ullah Z, Xie X, Harms K, Baik MH, Meggers E. Catalytic Asymmetric Dearomatization by Visible-Light-Activated [2+2] Photocycloaddition. Angewandte Chemie (International Ed. in English). PMID 29624849 DOI: 10.1002/anie.201802891  0.92
2018 Chen S, Zheng Y, Cui T, Meggers E, Houk KN. Arylketone π-Conjugation Controls Enantioselectivity in Asymmetric Alkynylations Catalyzed by Centrochiral Ruthenium Complexes. Journal of the American Chemical Society. PMID 29577723 DOI: 10.1021/jacs.8b00485  0.72
2018 Huang X, Lin J, Shen T, Harms K, Marchini M, Ceroni P, Meggers E. Asymmetric [3+2] Photocycloadditions of Cyclopropanes with Alkenes or Alkynes via Visible Light Excitation of Catalyst-Bound Substrates. Angewandte Chemie (International Ed. in English). PMID 29543370 DOI: 10.1002/anie.201802316  0.92
2018 Ma J, Zhang X, Huang X, Luo S, Meggers E. Preparation of chiral-at-metal catalysts and their use in asymmetric photoredox chemistry. Nature Protocols. 13: 605-632. PMID 29494576 DOI: 10.1038/nprot.2017.138  0.72
2017 Huang X, Li X, Xie X, Harms K, Riedel R, Meggers E. Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state. Nature Communications. 8: 2245. PMID 29269853 DOI: 10.1038/s41467-017-02148-1  0.92
2017 Ma J, Rosales AR, Huang X, Harms K, Riedel R, Wiest O, Meggers E. Visible-Light-Activated Asymmetric β-C-H Functionalization of Acceptor-Substituted Ketones with 1,2-Dicarbonyl Compounds. Journal of the American Chemical Society. PMID 29161036 DOI: 10.1021/jacs.7b09152  0.92
2017 Huang X, Luo S, Burghaus O, Webster RD, Harms K, Meggers E. Combining the catalytic enantioselective reaction of visible-light-generated radicals with a by-product utilization system. Chemical Science. 8: 7126-7131. PMID 29147543 DOI: 10.1039/c7sc02621h  0.92
2017 Chen S, Huang X, Meggers E, Houk KN. Origins of Enantioselectivity in Asymmetric Radical Additions to Octahedral Chiral-at-Rhodium Enolates: A Computational Study. Journal of the American Chemical Society. PMID 29143527 DOI: 10.1021/jacs.7b08650  0.56
2017 Ma J, Xie X, Meggers E. Catalytic Asymmetric Synthesis of Fluoroalkyl-Containing Compounds Via Three-Component Photoredox Chemistry. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29105857 DOI: 10.1002/chem.201704619  0.76
2017 Zhou Z, Li Y, Han B, Gong L, Meggers E. Enantioselective catalytic β-amination through proton-coupled electron transfer followed by stereocontrolled radical-radical coupling. Chemical Science. 8: 5757-5763. PMID 28989615 DOI: 10.1039/c7sc02031g  1
2017 Zhang L, Meggers E. Stereogenic-Only-at-Metal Asymmetric Catalysts. Chemistry, An Asian Journal. PMID 28782915 DOI: 10.1002/asia.201700739  0.72
2017 Luo S, Zhang X, Zheng Y, Harms K, Zhang L, Meggers E. Enantioselective Alkynylation of Aromatic Aldehydes Catalyzed by a Sterically Highly Demanding Chiral-at-Rhodium Lewis Acid. The Journal of Organic Chemistry. PMID 28759724 DOI: 10.1021/acs.joc.7b01394  0.92
2017 Yuan W, Zhou Z, Gong L, Meggers E. Asymmetric alkylation of remote C(sp(3))-H bonds by combining proton-coupled electron transfer with chiral Lewis acid catalysis. Chemical Communications (Cambridge, England). PMID 28745750 DOI: 10.1039/c7cc04941b  1
2017 Li Y, Lei M, Yuan W, Meggers E, Gong L. An N-heterocyclic carbene iridium catalyst with metal-centered chirality for enantioselective transfer hydrogenation of imines. Chemical Communications (Cambridge, England). PMID 28677698 DOI: 10.1039/c7cc04691j  1
2017 Huang X, Quinn TR, Harms K, Webster RD, Zhang L, Wiest O, Meggers E. Direct Visible-Light-Excited Asymmetric Lewis Acid Catalysis of Intermolecular [2+2] Photocycloadditions. Journal of the American Chemical Society. PMID 28644024 DOI: 10.1021/jacs.7b04363  0.92
2017 Mietke T, Cruchter T, Winterling E, Tripp M, Harms K, Meggers E. Suzuki Cross-Coupling for Post-Complexation Derivatization of Non-Racemic Bis-Cyclometalated Iridium(III) Complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28560718 DOI: 10.1002/chem.201701758  0.92
2017 Tutkowski B, Meggers E, Wiest O. Understanding Rate Acceleration and Stereoinduction of an Asymmetric Giese Reaction Mediated by a Chiral Rhodium Catalyst. Journal of the American Chemical Society. PMID 28558465 DOI: 10.1021/jacs.7b01786  0.36
2017 Lin H, Zhou Z, Cai J, Han B, Gong L, Meggers E. Asymmetric Construction of 3,3-Disubstituted Oxindoles Bearing Vicinal Quaternary-Tertiary Carbon Stereocenters Catalyzed by a Chiral-at-Rhodium Complex. The Journal of Organic Chemistry. PMID 28551996 DOI: 10.1021/acs.joc.7b00793  1
2017 Feng L, Dai X, Meggers E, Gong L. Three-Component Asymmetric Mannich Reaction Catalyzed by a Lewis Acid with Rhodium-Centered Chirality. Chemistry, An Asian Journal. PMID 28299898 DOI: 10.1002/asia.201700189  1
2017 Zheng Y, Tan Y, Harms K, Zhang L, Meggers E. Octahedral Ruthenium Complex with Exclusive Metal-Centered Chirality for Highly Effective Asymmetric Catalysis. Journal of the American Chemical Society. PMID 28290685 DOI: 10.1021/jacs.7b01098  0.92
2017 Zhang L, Meggers E. Steering Asymmetric Lewis Acid Catalysis Exclusively with Octahedral Metal-Centered Chirality. Accounts of Chemical Research. PMID 28128920 DOI: 10.1021/acs.accounts.6b00586  0.72
2016 Zhou Z, Li Y, Gong L, Meggers E. Enantioselective 2-Alkylation of 3-Substituted Indoles with Dual Chiral Lewis Acid/Hydrogen-Bond-Mediated Catalyst. Organic Letters. PMID 28026183 DOI: 10.1021/acs.orglett.6b03500  1
2016 Wang C, Harms K, Meggers E. Catalytic Asymmetric Csp3 -H Functionalization under Photoredox Conditions by Radical Translocation and Stereocontrolled Alkene Addition. Angewandte Chemie (International Ed. in English). PMID 27667745 DOI: 10.1002/anie.201607305  0.92
2016 Huang X, Webster RD, Harms K, Meggers E. Asymmetric Catalysis with Organic Azides and Diazo Compounds Initiated by Photoinduced Electron Transfer. Journal of the American Chemical Society. PMID 27577929 DOI: 10.1021/jacs.6b07692  0.92
2016 Ma J, Harms K, Meggers E. Enantioselective rhodium/ruthenium photoredox catalysis en route to chiral 1,2-aminoalcohols. Chemical Communications (Cambridge, England). PMID 27462824 DOI: 10.1039/c6cc04397f  0.92
2016 Shannan B, Watters A, Chen Q, Mollin S, Dörr M, Meggers E, Xu X, Gimotty PA, Perego M, Li L, Benci J, Krepler C, Brafford P, Zhang J, Wei Z, et al. PIM kinases as therapeutic targets against advanced melanoma. Oncotarget. PMID 27448973 DOI: 10.18632/oncotarget.10703  0.6
2016 Xu W, Arieno M, Löw H, Huang K, Xie X, Cruchter T, Ma Q, Xi J, Huang B, Wiest O, Gong L, Meggers E. Metal-Templated Design: Enantioselective Hydrogen-Bond-Driven Catalysis Requiring Only Parts-per-Million Catalyst Loading. Journal of the American Chemical Society. PMID 27336458 DOI: 10.1021/jacs.6b02769  1
2016 Meggers E, Zheng Y, Zhang L, Harms K. Enantioselective Alkynylation of 2-Trifluoroacetyl Imidazoles Catalyzed by Bis-Cyclometalated Rhodium(III) Complexes Containing Pinene-Derived Ligands. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27312941 DOI: 10.1002/chem.201602372  0.92
2016 Song L, Gong L, Meggers E. Asymmetric dual catalysis via fragmentation of a single rhodium precursor complex. Chemical Communications (Cambridge, England). PMID 27231188 DOI: 10.1039/c6cc03157a  1
2016 Huo H, Harms K, Meggers E. Catalytic, Enantioselective Addition of Alkyl Radicals to Alkenes via Visible-Light-Activated Photoredox Catalysis with a Chiral Rhodium Complex. Journal of the American Chemical Society. PMID 27218134 DOI: 10.1021/jacs.6b03399  1
2016 Meggers E, Shen X, Harms K, Marsch M. Rhodium Catalyst Superior Over Iridium Congeners for Enantioselective Radical Amination Activated by Visible Light. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27145893 DOI: 10.1002/chem.201601572  0.92
2016 Ma J, Shen X, Harms K, Meggers E. Expanding the family of bis-cyclometalated chiral-at-metal rhodium(iii) catalysts with a benzothiazole derivative. Dalton Transactions (Cambridge, England : 2003). PMID 27143346 DOI: 10.1039/c6dt01063f  0.92
2016 Tian C, Gong L, Meggers E. Chiral-at-metal iridium complex for efficient enantioselective transfer hydrogenation of ketones. Chemical Communications (Cambridge, England). PMID 26911401 DOI: 10.1039/c6cc00972g  1
2015 Wang C, Chen LA, Huo H, Shen X, Harms K, Gong L, Meggers E. Asymmetric Lewis acid catalysis directed by octahedral rhodium centrochirality. Chemical Science. 6: 1094-1100. PMID 29560197 DOI: 10.1039/c4sc03101f  1
2015 Wang C, Qin J, Shen X, Riedel R, Harms K, Meggers E. Asymmetric Radical-Radical Cross-Coupling through Visible-Light-Activated Iridium Catalysis. Angewandte Chemie (International Ed. in English). PMID 26629641 DOI: 10.1002/anie.201509524  1
2015 Ritter C, Nett N, Acevedo-Rocha CG, Lonsdale R, Kräling K, Dempwolff F, Hoebenreich S, Graumann PL, Reetz MT, Meggers E. Bioorthogonal Enzymatic Activation of Caged Compounds. Angewandte Chemie (International Ed. in English). 54: 13440-3. PMID 26356324 DOI: 10.1002/anie.201506739  1
2015 Tan Y, Yuan W, Gong L, Meggers E. Aerobic Asymmetric Dehydrogenative Cross-Coupling between Two C sp 3H Groups Catalyzed by a Chiral-at-Metal Rhodium Complex. Angewandte Chemie (International Ed. in English). 54: 13045-8. PMID 26351096 DOI: 10.1002/anie.201506273  1
2015 Huang Y, Song L, Gong L, Meggers E. Asymmetric Synthesis of Hydrocarbazoles Catalyzed by an Octahedral Chiral-at-Rhodium Lewis Acid. Chemistry, An Asian Journal. PMID 26344422 DOI: 10.1002/asia.201500764  1
2015 Rajaratnam R, Martin EK, Dörr M, Harms K, Casini A, Meggers E. Correlation between the Stereochemistry and Bioactivity in Octahedral Rhodium Prolinato Complexes. Inorganic Chemistry. 54: 8111-20. PMID 26251218 DOI: 10.1021/acs.inorgchem.5b01349  1
2015 Huo H, Wang C, Harms K, Meggers E. Enantioselective, Catalytic Trichloromethylation through Visible-Light-Activated Photoredox Catalysis with a Chiral Iridium Complex. Journal of the American Chemical Society. PMID 26193928 DOI: 10.1021/jacs.5b06010  1
2015 Shen X, Huo H, Wang C, Zhang B, Harms K, Meggers E. Octahedral Chiral-at-Metal Iridium Catalysts: Versatile Chiral Lewis Acids for Asymmetric Conjugate Additions. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 9720-6. PMID 26033287 DOI: 10.1002/chem.201500922  1
2015 Wang C, Zheng Y, Huo H, Röse P, Zhang L, Harms K, Hilt G, Meggers E. Merger of visible light induced oxidation and enantioselective alkylation with a chiral iridium catalyst. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 7355-9. PMID 25832794 DOI: 10.1002/chem.201500998  1
2015 Mollin S, Riedel R, Harms K, Meggers E. Octahedral rhodium(III) complexes as kinase inhibitors: Control of the relative stereochemistry with acyclic tridentate ligands. Journal of Inorganic Biochemistry. 148: 11-21. PMID 25660487 DOI: 10.1016/j.jinorgbio.2015.01.005  1
2015 Qin J, Rajaratnam R, Feng L, Salami J, Barber-Rotenberg JS, Domsic J, Reyes-Uribe P, Liu H, Dang W, Berger SL, Villanueva J, Meggers E, Marmorstein R. Development of organometallic S6K1 inhibitors. Journal of Medicinal Chemistry. 58: 305-14. PMID 25356520 DOI: 10.1021/jm5011868  1
2014 Huo H, Shen X, Wang C, Zhang L, Röse P, Chen LA, Harms K, Marsch M, Hilt G, Meggers E. Asymmetric photoredox transition-metal catalysis activated by visible light. Nature. 515: 100-3. PMID 25373679 DOI: 10.1038/nature13892  1
2014 Gong L, Chen LA, Meggers E. Asymmetric catalysis mediated by the ligand sphere of octahedral chiral-at-metal complexes. Angewandte Chemie (International Ed. in English). 53: 10868-74. PMID 25156957 DOI: 10.1002/anie.201404305  1
2014 Völker T, Dempwolff F, Graumann PL, Meggers E. Progress towards bioorthogonal catalysis with organometallic compounds. Angewandte Chemie (International Ed. in English). 53: 10536-40. PMID 25138780 DOI: 10.1002/anie.201404547  0.4
2014 Ma J, Ding X, Hu Y, Huang Y, Gong L, Meggers E. Metal-templated chiral Brønsted base organocatalysis. Nature Communications. 5: 4531. PMID 25072163 DOI: 10.1038/ncomms5531  1
2014 Huo H, Fu C, Wang C, Harms K, Meggers E. Metal-templated enantioselective enamine/H-bonding dual activation catalysis. Chemical Communications (Cambridge, England). 50: 10409-11. PMID 25068974 DOI: 10.1039/c4cc04636f  1
2014 Wähler K, Ludewig A, Szabo P, Harms K, Meggers E. Rhenium Complexes with Red-Light-Induced Anticancer Activity. European Journal of Inorganic Chemistry. 2014: 807-811. PMID 25050081 DOI: 10.1002/ejic.201301474  1
2014 Huo H, Fu C, Harms K, Meggers E. Asymmetric catalysis with substitutionally labile yet stereochemically stable chiral-at-metal iridium(III) complex. Journal of the American Chemical Society. 136: 2990-3. PMID 24754748 DOI: 10.1021/ja4132505  1
2014 Streib M, Kräling K, Richter K, Xie X, Steuber H, Meggers E. An organometallic inhibitor for the human repair enzyme 7,8-dihydro-8-oxoguanosine triphosphatase. Angewandte Chemie (International Ed. in English). 53: 305-9. PMID 24258965 DOI: 10.1002/anie.201307849  1
2013 Wähler K, Kräling K, Steuber H, Meggers E. Non-ATP-Mimetic Organometallic Protein Kinase Inhibitor. Chemistryopen. 2: 180-5. PMID 24551564 DOI: 10.1002/open.201300031  0.76
2013 Chen LA, Tang X, Xi J, Xu W, Gong L, Meggers E. Chiral-at-metal octahedral iridium catalyst for the asymmetric construction of an all-carbon quaternary stereocenter. Angewandte Chemie (International Ed. in English). 52: 14021-5. PMID 24214333 DOI: 10.1002/anie.201306997  1
2013 Cruchter T, Harms K, Meggers E. Strain-promoted azide-alkyne cycloaddition with ruthenium(II)-azido complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 16682-9. PMID 24173767 DOI: 10.1002/chem.201302502  1
2013 Huang B, Wang L, Gong L, Meggers E. Chiral enol oxazolines and thiazolines as auxiliary ligands for the asymmetric synthesis of ruthenium-polypyridyl complexes. Chemistry, An Asian Journal. 8: 2274-80. PMID 23818279 DOI: 10.1002/asia.201300598  1
2013 Gong L, Wenzel M, Meggers E. Chiral-auxiliary-mediated asymmetric synthesis of ruthenium polypyridyl complexes. Accounts of Chemical Research. 46: 2635-44. PMID 23730834 DOI: 10.1021/ar400083u  1
2013 Rao L, Zhang IY, Guo W, Feng L, Meggers E, Xu X. Nonfitting protein-ligand interaction scoring function based on first-principles theoretical chemistry methods: development and application on kinase inhibitors. Journal of Computational Chemistry. 34: 1636-46. PMID 23681957 DOI: 10.1002/jcc.23303  0.6
2013 Chen LA, Xu W, Huang B, Ma J, Wang L, Xi J, Harms K, Gong L, Meggers E. Asymmetric catalysis with an inert chiral-at-metal iridium complex. Journal of the American Chemical Society. 135: 10598-601. PMID 23672419 DOI: 10.1021/ja403777k  1
2013 Kastl A, Dieckmann S, Wähler K, Völker T, Kastl L, Merkel AL, Vultur A, Shannan B, Harms K, Ocker M, Parak WJ, Herlyn M, Meggers E. Rhenium complexes with visible-light-induced anticancer activity. Chemmedchem. 8: 924-7. PMID 23568508 DOI: 10.1002/cmdc.201300060  1
2013 Chen LA, Ding X, Gong L, Meggers E. Thioether-based anchimeric assistance for asymmetric coordination chemistry with ruthenium(II) and osmium(II). Dalton Transactions (Cambridge, England : 2003). 42: 5623-6. PMID 23503568 DOI: 10.1039/c3dt00015j  1
2013 Sasmal PK, Streu CN, Meggers E. Metal complex catalysis in living biological systems. Chemical Communications (Cambridge, England). 49: 1581-7. PMID 23250079 DOI: 10.1039/c2cc37832a  1
2012 Fu C, Wenzel M, Treutlein E, Harms K, Meggers E. Proline as chiral auxiliary for the economical asymmetric synthesis of ruthenium(II) polypyridyl complexes. Inorganic Chemistry. 51: 10004-11. PMID 22946499 DOI: 10.1021/ic3015157  1
2012 Chen LA, Ma J, Celik MA, Yu HL, Cao Z, Frenking G, Gong L, Meggers E. Active versus passive substituent participation in the auxiliary-mediated asymmetric synthesis of an octahedral metal complex. Chemistry, An Asian Journal. 7: 2523-6. PMID 22915359 DOI: 10.1002/asia.201200532  1
2012 John JK, Paraiso KH, Rebecca VW, Cantini LP, Abel EV, Pagano N, Meggers E, Mathew R, Krepler C, Izumi V, Fang B, Koomen JM, Messina JL, Herlyn M, Smalley KS. GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation. The Journal of Investigative Dermatology. 132: 2818-27. PMID 22810307 DOI: 10.1038/jid.2012.237  1
2012 Blanck S, Geisselbrecht Y, Kräling K, Middel S, Mietke T, Harms K, Essen LO, Meggers E. Bioactive cyclometalated phthalimides: design, synthesis and kinase inhibition. Dalton Transactions (Cambridge, England : 2003). 41: 9337-48. PMID 22733119 DOI: 10.1039/c2dt30940h  1
2012 Xiang Y, Fu C, Breiding T, Sasmal PK, Liu H, Shen Q, Harms K, Zhang L, Meggers E. Hydrolytically stable octahedral silicon complexes as bioactive scaffolds: application to the design of DNA intercalators. Chemical Communications (Cambridge, England). 48: 7131-3. PMID 22588541 DOI: 10.1039/c2cc32506c  1
2012 Sasmal PK, Carregal-Romero S, Han AA, Streu CN, Lin Z, Namikawa K, Elliott SL, Köster RW, Parak WJ, Meggers E. Catalytic azide reduction in biological environments. Chembiochem : a European Journal of Chemical Biology. 13: 1116-20. PMID 22514188 DOI: 10.1002/cbic.201100719  1
2012 Blanck S, Maksimoska J, Baumeister J, Harms K, Marmorstein R, Meggers E. The art of filling protein pockets efficiently with octahedral metal complexes. Angewandte Chemie (International Ed. in English). 51: 5244-6. PMID 22383326 DOI: 10.1002/anie.201108865  1
2012 Kastl A, Wilbuer A, Merkel AL, Feng L, Di Fazio P, Ocker M, Meggers E. Dual anticancer activity in a single compound: visible-light-induced apoptosis by an antiangiogenic iridium complex. Chemical Communications (Cambridge, England). 48: 1863-5. PMID 22057186 DOI: 10.1039/c1cc15378a  1
2011 Lin Z, Celik MA, Fu C, Harms K, Frenking G, Meggers E. N-sulfinylcarboximidates as a new class of chiral bidentate ligands: application to asymmetric coordination chemistry. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 12602-5. PMID 21956729 DOI: 10.1002/chem.201101886  0.92
2011 Blanck S, Cruchter T, Vultur A, Riedel R, Harms K, Herlyn M, Meggers E. Organometallic Pyridylnaphthalimide Complexes as Protein Kinase Inhibitors. Organometallics. 30: 4598-4606. PMID 21918590 DOI: 10.1021/om200366r  0.92
2011 Johnson AT, Schlegel MK, Meggers E, Essen LO, Wiest O. On the structure and dynamics of duplex GNA. The Journal of Organic Chemistry. 76: 7964-74. PMID 21838272 DOI: 10.1021/jo201469b  1
2011 Feng L, Geisselbrecht Y, Blanck S, Wilbuer A, Atilla-Gokcumen GE, Filippakopoulos P, Kräling K, Celik MA, Harms K, Maksimoska J, Marmorstein R, Frenking G, Knapp S, Essen LO, Meggers E. Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors. Journal of the American Chemical Society. 133: 5976-86. PMID 21446733 DOI: 10.1021/ja1112996  1
2011 Lin Z, Gong L, Celik MA, Harms K, Frenking G, Meggers E. Asymmetric coordination chemistry by chiral-auxiliary-mediated dynamic resolution under thermodynamic control. Chemistry, An Asian Journal. 6: 474-81. PMID 21254425 DOI: 10.1002/asia.201000555  1
2011 Atilla-Gokcumen GE, Di Costanzo L, Meggers E. Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3β. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 16: 45-50. PMID 20821241 DOI: 10.1007/s00775-010-0699-x  0.96
2010 Mulcahy SP, Gründler K, Frias C, Wagner L, Prokop A, Meggers E. Discovery of a strongly apoptotic ruthenium complex through combinatorial coordination chemistry. Dalton Transactions (Cambridge, England : 2003). 39: 8177-82. PMID 20689887 DOI: 10.1039/c0dt00034e  1
2010 Gong L, Lin Z, Harms K, Meggers E. Isomerization-induced asymmetric coordination chemistry: from auxiliary control to asymmetric catalysis. Angewandte Chemie (International Ed. in English). 49: 7955-7. PMID 20672273 DOI: 10.1002/anie.201003139  1
2010 Gong L, Mulcahy SP, Devarajan D, Harms K, Frenking G, Meggers E. Chiral salicyloxazolines as auxiliaries for the asymmetric synthesis of ruthenium polypyridyl complexes. Inorganic Chemistry. 49: 7692-9. PMID 20666500 DOI: 10.1021/ic100229e  1
2010 He X, Gong L, Kräling K, Gründler K, Frias C, Webster RD, Meggers E, Prokop A, Xia H. Unusual eta2-allene osmacycle with apoptotic properties. Chembiochem : a European Journal of Chemical Biology. 11: 1607-13. PMID 20575131 DOI: 10.1002/cbic.201000055  1
2010 Wilbuer A, Vlecken DH, Schmitz DJ, Kräling K, Harms K, Bagowski CP, Meggers E. Iridium complex with antiangiogenic properties. Angewandte Chemie (International Ed. in English). 49: 3839-42. PMID 20437440 DOI: 10.1002/anie.201000682  1
2010 Meggers E, Zhang L. Synthesis and properties of the simplified nucleic acid glycol nucleic acid. Accounts of Chemical Research. 43: 1092-102. PMID 20405911 DOI: 10.1021/ar900292q  0.72
2010 Schlegel MK, Essen LO, Meggers E. Atomic resolution duplex structure of the simplified nucleic acid GNA. Chemical Communications (Cambridge, England). 46: 1094-6. PMID 20126724 DOI: 10.1039/b916851f  1
2009 Meggers E, Atilla-Gokcumen GE, Gründler K, Frias C, Prokop A. Inert ruthenium half-sandwich complexes with anticancer activity. Dalton Transactions (Cambridge, England : 2003). 10882-8. PMID 20023918 DOI: 10.1039/b917792b  1
2009 Pagano N, Wong EY, Breiding T, Liu H, Wilbuer A, Bregman H, Shen Q, Diamond SL, Meggers E. From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors. The Journal of Organic Chemistry. 74: 8997-9009. PMID 19886617 DOI: 10.1021/jo901641k  1
2009 Bullock AN, Russo S, Amos A, Pagano N, Bregman H, Debreczeni JE, Lee WH, von Delft F, Meggers E, Knapp S. Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor. Plos One. 4: e7112. PMID 19841674 DOI: 10.1371/journal.pone.0007112  1
2009 Gong L, Mulcahy SP, Harms K, Meggers E. Chiral-auxiliary-mediated asymmetric synthesis of tris-heteroleptic ruthenium polypyridyl complexes. Journal of the American Chemical Society. 131: 9602-3. PMID 19555100 DOI: 10.1021/ja9031665  1
2009 Schlegel MK, Meggers E. Improved phosphoramidite building blocks for the synthesis of the simplified nucleic acid GNA. The Journal of Organic Chemistry. 74: 4615-8. PMID 19441799 DOI: 10.1021/jo900365a  1
2009 Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase. Biochemistry. 48: 5187-98. PMID 19371126 DOI: 10.1021/bi802067u  1
2009 Anand R, Maksimoska J, Pagano N, Wong EY, Gimotty PA, Diamond SL, Meggers E, Marmorstein R. Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor. Journal of Medicinal Chemistry. 52: 1602-11. PMID 19226137 DOI: 10.1021/jm8005806  1
2009 Schlegel MK, Zhang L, Pagano N, Meggers E. Metal-mediated base pairing within the simplified nucleic acid GNA. Organic & Biomolecular Chemistry. 7: 476-82. PMID 19156312 DOI: 10.1039/b816142a  1
2009 Schlegel MK, Xie X, Zhang L, Meggers E. Insight into the high duplex stability of the simplified nucleic acid GNA. Angewandte Chemie (International Ed. in English). 48: 960-3. PMID 19130516 DOI: 10.1002/anie.200803472  1
2009 Xie X, Mulcahy SP, Meggers E. Strategy for the stereochemical assignment of tris-heteroleptic Ru(II) complexes by NMR spectroscopy. Inorganic Chemistry. 48: 1053-61. PMID 19105744 DOI: 10.1021/ic801744a  1
2008 Streu C, Carroll PJ, Kohli RK, Meggers E. Synthesis of cyclopentadienyl ruthenium complexes bearing pendant chelating picolinates through an electrophilic precursor. Journal of Organometallic Chemistry. 693: 551-556. PMID 19190711 DOI: 10.1016/j.jorganchem.2007.11.024  1
2008 Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E. Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3. Chembiochem : a European Journal of Chemical Biology. 9: 2933-6. PMID 19035373 DOI: 10.1002/cbic.200800489  1
2008 Maksimoska J, Feng L, Harms K, Yi C, Kissil J, Marmorstein R, Meggers E. Targeting large kinase active site with rigid, bulky octahedral ruthenium complexes. Journal of the American Chemical Society. 130: 15764-5. PMID 18973295 DOI: 10.1021/ja805555a  1
2008 Schlegel MK, Essen LO, Meggers E. Duplex structure of a minimal nucleic acid. Journal of the American Chemical Society. 130: 8158-9. PMID 18529005 DOI: 10.1021/ja802788g  1
2008 Xie P, Williams DS, Atilla-Gokcumen GE, Milk L, Xiao M, Smalley KS, Herlyn M, Meggers E, Marmorstein R. Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity. Acs Chemical Biology. 3: 305-16. PMID 18484710 DOI: 10.1021/cb800039y  1
2008 Maksimoska J, Williams DS, Atilla-Gokcumen GE, Smalley KS, Carroll PJ, Webster RD, Filippakopoulos P, Knapp S, Herlyn M, Meggers E. Similar biological activities of two isostructural ruthenium and osmium complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 4816-22. PMID 18425743 DOI: 10.1002/chem.200800294  1
2008 David SS, Meggers E. Inorganic chemical biology: from small metal complexes in biological systems to metalloproteins. Current Opinion in Chemical Biology. 12: 194-6. PMID 18374664 DOI: 10.1016/j.cbpa.2008.03.008  1
2008 Mulcahy SP, Li S, Korn R, Xie X, Meggers E. Solid-phase synthesis of tris-heteroleptic ruthenium(II) complexes and application to acetylcholinesterase inhibition. Inorganic Chemistry. 47: 5030-2. PMID 18373338 DOI: 10.1021/ic800080b  1
2007 Schlegel MK, Peritz AE, Kittigowittana K, Zhang L, Meggers E. Duplex formation of the simplified nucleic acid GNA. Chembiochem : a European Journal of Chemical Biology. 8: 927-32. PMID 17465439 DOI: 10.1002/cbic.200600435  1
2007 Pagano N, Maksimoska J, Bregman H, Williams DS, Webster RD, Xue F, Meggers E. Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand. Organic & Biomolecular Chemistry. 5: 1218-27. PMID 17406720 DOI: 10.1039/b700433h  1
2007 Williams DS, Carroll PJ, Meggers E. Platinum complex as a nanomolar protein kinase inhibitor. Inorganic Chemistry. 46: 2944-6. PMID 17375909 DOI: 10.1021/ic062055t  1
2007 Smalley KS, Contractor R, Haass NK, Kulp AN, Atilla-Gokcumen GE, Williams DS, Bregman H, Flaherty KT, Soengas MS, Meggers E, Herlyn M. An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells. Cancer Research. 67: 209-17. PMID 17210701 DOI: 10.1158/0008-5472.CAN-06-1538  1
2006 Mulcahy SP, Carroll PJ, Meggers E. Synthesis and cyclometalation of a pyrido[3,2-e]-2,10b-diaza-cyclopenta[c]fluorene-1,3-dione scaffold. Tetrahedron Letters. 47: 8877-8880. PMID 18071577 DOI: 10.1016/j.tetlet.2006.10.054  1
2006 Bregman H, Meggers E. Ruthenium half-sandwich complexes as protein kinase inhibitors: an N-succinimidyl ester for rapid derivatizations of the cyclopentadienyl moiety. Organic Letters. 8: 5465-8. PMID 17107048 DOI: 10.1021/ol0620646  0.96
2006 Atilla-Gokcumen GE, Williams DS, Bregman H, Pagano N, Meggers E. Organometallic compounds with biological activity: a very selective and highly potent cellular inhibitor for glycogen synthase kinase 3. Chembiochem : a European Journal of Chemical Biology. 7: 1443-50. PMID 16858717 DOI: 10.1002/cbic.200600117  1
2006 Streu C, Meggers E. Ruthenium-induced allylcarbamate cleavage in living cells. Angewandte Chemie (International Ed. in English). 45: 5645-8. PMID 16856188 DOI: 10.1002/anie.200601752  0.6
2006 Bregman H, Carroll PJ, Meggers E. Rapid access to unexplored chemical space by ligand scanning around a ruthenium center: discovery of potent and selective protein kinase inhibitors. Journal of the American Chemical Society. 128: 877-84. PMID 16417378 DOI: 10.1021/ja055523r  0.96
2006 Debreczeni JE, Bullock AN, Atilla GE, Williams DS, Bregman H, Knapp S, Meggers E. Ruthenium half-sandwich complexes bound to protein kinase Pim-1. Angewandte Chemie (International Ed. in English). 45: 1580-5. PMID 16381041 DOI: 10.1002/anie.200503468  0.96
2005 Zhang L, Peritz A, Meggers E. A simple glycol nucleic acid. Journal of the American Chemical Society. 127: 4174-5. PMID 15783191 DOI: 10.1021/ja042564z  0.72
2005 Williams DS, Atilla GE, Bregman H, Arzoumanian A, Klein PS, Meggers E. Switching on a signaling pathway with an organoruthenium complex. Angewandte Chemie (International Ed. in English). 44: 1984-7. PMID 15742314 DOI: 10.1002/anie.200462501  0.96
2005 Zhang L, Meggers E. An extremely stable and orthogonal DNA base pair with a simplified three-carbon backbone. Journal of the American Chemical Society. 127: 74-5. PMID 15631455 DOI: 10.1021/ja043904j  0.72
2004 Bregman H, Williams DS, Atilla GE, Carroll PJ, Meggers E. An organometallic inhibitor for glycogen synthase kinase 3. Journal of the American Chemical Society. 126: 13594-5. PMID 15493898 DOI: 10.1021/ja046049c  0.96
2004 Zhang L, Carroll P, Meggers E. Ruthenium complexes as protein kinase inhibitors. Organic Letters. 6: 521-3. PMID 14961613 DOI: 10.1021/ol036283s  0.72
2004 Zimmermann N, Meggers E, Schultz PG. A second-generation copper(II)-mediated metallo-DNA-base pair. Bioorganic Chemistry. 32: 13-25. PMID 14700559  0.68
2003 Chin JW, Cropp TA, Chu S, Meggers E, Schultz PG. Progress toward an expanded eukaryotic genetic code. Chemistry & Biology. 10: 511-9. PMID 12837384 DOI: 10.1016/S1074-5521(03)00123-6  1
2002 Zimmermann N, Meggers E, Schultz PG. A novel silver(i)-mediated DNA base pair. Journal of the American Chemical Society. 124: 13684-5. PMID 12431092  0.68
2001 Atwell S, Meggers E, Spraggon G, Schultz PG. Structure of a copper-mediated base pair in DNA. Journal of the American Chemical Society. 123: 12364-7. PMID 11734038  0.68
2000 Meggers E, Dussy A, Schäfer T, Giese B. Electron transfer in DNA from guanine and 8-oxoguanine to a radical cation of the carbohydrate backbone. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 485-92. PMID 10747415 DOI: 10.1002/(SICI)1521-3765(20000204)6:3<485::AID-CHEM485>3.0.CO;2-A  1
1999 Giese B, Wessely S, Spormann M, Lindemann U, Meggers E, Michel-Beyerle ME. On the Mechanism of Long-Range Electron Transfer through DNA. Angewandte Chemie (International Ed. in English). 38: 996-998. PMID 29711867 DOI: 10.1002/(SICI)1521-3773(19990401)38:7<996::AID-ANIE996>3.0.CO;2-4  0.76
1998 Meggers E, Kusch D, Spichty M, Wille U, Giese B. Electron Transfer through DNA in the Course of Radical-Induced Strand Cleavage. Angewandte Chemie (International Ed. in English). 37: 460-462. PMID 29711175 DOI: 10.1002/(SICI)1521-3773(19980302)37:4<460::AID-ANIE460>3.0.CO;2-U  0.76
Show low-probability matches.