Year |
Citation |
Score |
2024 |
Bailey EP, Donohoe TJ, Smith MD. Functional group tolerant hydrogen borrowing C-alkylation. Nature Communications. 15: 5131. PMID 38879563 DOI: 10.1038/s41467-024-49249-2 |
0.514 |
|
2020 |
Popescu M, Mekareeya A, Alegre-Requena J, Paton R, Smith MD. Visible light mediated heterocycle functionalization via a geometrically interrupted [2+2] cycloaddition. Angewandte Chemie (International Ed. in English). PMID 32856748 DOI: 10.1002/Anie.202009704 |
0.322 |
|
2019 |
Jones B, Balan T, Jolliffe J, Campbell C, Smith MD. Practical and scalable kinetic resolution of BINOLs mediated by a chiral counterion. Angewandte Chemie (International Ed. in English). PMID 30779415 DOI: 10.1002/Anie.201814381 |
0.37 |
|
2019 |
Fugard A, Lahdenperä A, Mekareeya A, Tan J, Paton R, Smith MD. Hydrogen bond enabled dynamic kinetic resolution of axially chiral amides mediated by a chiral counterion. Angewandte Chemie (International Ed. in English). PMID 30644159 DOI: 10.1002/Anie.201814362 |
0.318 |
|
2018 |
Johnson TC, Elbert BL, Farley AJM, Gorman TW, Genicot C, Lallemand B, Pasau P, Flasz J, Castro JL, MacCoss M, Dixon DJ, Paton RS, Schofield CJ, Smith MD, Willis MC. Direct sulfonylation of anilines mediated by visible light. Chemical Science. 9: 629-633. PMID 29629128 DOI: 10.1039/C7Sc03891G |
0.644 |
|
2017 |
Gerken P, Wolstenhulme J, Tumber A, Hatch S, Zhang Y, Müller S, Chandler S, Mair B, Li F, Nijman S, Konietzny R, Szommer T, Yapp C, Fedorov O, Benesch J, ... ... Smith MD, et al. Discovery of a highly selective cell-active inhibitor of KDM2/7. Angewandte Chemie (International Ed. in English). PMID 28976073 DOI: 10.1002/Anie.201706788 |
0.396 |
|
2017 |
Elbert B, Farley A, Gorman T, Johnson T, Genicot C, Lallemand B, Pasau P, Flasz J, Castro J, Maccoss M, Paton R, Schofield C, Smith M, Willis M, Dixon DJ. A C-H Cyanation of 6-Ring N-Containing Heteroaromatics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28833674 DOI: 10.1002/Chem.201703931 |
0.64 |
|
2017 |
Smith MD, Münster N, Parker N, van Dijk L, Paton R. Visible light photocatalysis of 6π heterocyclization. Angewandte Chemie (International Ed. in English). PMID 28640479 DOI: 10.1002/Anie.201705333 |
0.328 |
|
2017 |
Jolliffe JD, Armstrong RJ, Smith MD. Catalytic enantioselective synthesis of atropisomeric biaryls by a cation-directed O-alkylation. Nature Chemistry. 9: 558-562. PMID 28537599 DOI: 10.1038/Nchem.2710 |
0.382 |
|
2017 |
Borissov A, Lim JY, Brown A, Christensen KE, Thompson AL, Smith MD, Beer PD. Neutral iodotriazole foldamers as tetradentate halogen bonding anion receptors. Chemical Communications (Cambridge, England). PMID 28181604 DOI: 10.1039/C7Cc00727B |
0.311 |
|
2016 |
Kiss E, Campbell CD, Driver RW, Jolliffe JD, Lang R, Sergeieva T, Okovytyy S, Paton RS, Smith MD. A Counterion-Directed Approach to the Diels-Alder Paradigm: Cascade Synthesis of Tricyclic Fused Cyclopropanes. Angewandte Chemie (International Ed. in English). PMID 27714921 DOI: 10.1002/Anie.201608534 |
0.354 |
|
2016 |
Lamb AD, Davey PD, Driver RW, Thompson AL, Smith MD. Enantioselective Synthesis of 4- and 6-Azaindolines by a Cation-Directed Cyclization. Organic Letters. PMID 27709963 DOI: 10.1021/Acs.Orglett.6B02744 |
0.369 |
|
2016 |
Rahemtulla BF, Clark HF, Smith MD. Catalytic Enantioselective Synthesis of C1 - and C2 -Symmetric Spirobiindanones through Counterion-Directed Enolate C-Acylation. Angewandte Chemie (International Ed. in English). PMID 27628946 DOI: 10.1002/Anie.201607731 |
0.365 |
|
2016 |
Johnston CP, Kothari A, Sergeieva T, Okovytyy SI, Jackson KE, Paton RS, Smith MD. Corrigendum: Catalytic enantioselective synthesis of indanes by a cation-directed 5-endo-trig cyclization. Nature Chemistry. 8: 281. PMID 26892563 DOI: 10.1038/Nchem.2457 |
0.357 |
|
2016 |
List B, Shevchenko GA, Rahemtulla BF, Clark HF, Smith MD. Asymmetric Synthesis of Spirobiindanones by Catalytic C-Acylation Synfacts. 12: 1302-1302. DOI: 10.1055/S-0036-1589456 |
0.359 |
|
2016 |
Armstrong RJ, D'Ascenzio M, Smith MD. Cation-Directed Enantioselective N-Functionalization of Pyrroles Synlett. 27: 6-10. DOI: 10.1055/S-0035-1560813 |
0.347 |
|
2015 |
Sharma K, Wolstenhulme JR, Painter PP, Yeo D, Grande-Carmona F, Johnston CP, Tantillo DJ, Smith MD. Cation-controlled enantio- and diastereoselective synthesis of indolines: an autoinductive phase-transfer initiated 5-endo-trig process. Journal of the American Chemical Society. PMID 26397716 DOI: 10.1021/Jacs.5B08834 |
0.363 |
|
2014 |
Chu S, Wallace S, Smith MD. A cascade strategy enables a total synthesis of (-)-gephyrotoxin. Angewandte Chemie (International Ed. in English). 53: 13826-9. PMID 25324224 DOI: 10.1002/Anie.201409038 |
0.564 |
|
2014 |
Armstrong RJ, Smith MD. Catalytic enantioselective synthesis of atropisomeric biaryls: a cation-directed nucleophilic aromatic substitution reaction. Angewandte Chemie (International Ed. in English). 53: 12822-6. PMID 25257677 DOI: 10.1002/Anie.201408205 |
0.392 |
|
2014 |
Wolstenhulme JR, Cavell A, Gredi?ak M, Driver RW, Smith MD. A cation-directed two-component cascade approach to enantioenriched pyrroloindolines. Chemical Communications (Cambridge, England). 50: 13585-8. PMID 25245762 DOI: 10.1039/C4Cc06683A |
0.354 |
|
2014 |
Knipe PC, Smith MD. Enantioselective one-pot synthesis of dihydroquinolones via BINOL-derived Lewis acid catalysis. Organic & Biomolecular Chemistry. 12: 5094-7. PMID 24927823 DOI: 10.1039/C4Ob00627E |
0.732 |
|
2014 |
Knipe PC, Gredi?ak M, Cernijenko A, Paton RS, Smith MD. Phase-transfer-catalysed synthesis of pyrroloindolines and pyridoindolines by a hydrogen-bond-assisted isocyanide cyclization cascade. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 3005-9. PMID 24523244 DOI: 10.1002/Chem.201400192 |
0.739 |
|
2013 |
Li M, Woods PA, Smith MD. Cation-directed enantioselective synthesis of quaternary-substituted indolenines Chemical Science. 4: 2907. DOI: 10.1039/C3Sc50592H |
0.409 |
|
2012 |
Jones CR, Baruah PK, Thompson AL, Scheiner S, Smith MD. Can a C-H···O interaction be a determinant of conformation? Journal of the American Chemical Society. 134: 12064-71. PMID 22789294 DOI: 10.1021/Ja301318A |
0.472 |
|
2012 |
MacIver EE, Knipe PC, Cridland AP, Thompson AL, Smith MD. Catalytic enantioselective electrocyclic cascades Chemical Science. 3: 537-540. DOI: 10.1039/C1Sc00697E |
0.728 |
|
2011 |
Thompson S, Coyne AG, Knipe PC, Smith MD. Asymmetric electrocyclic reactions. Chemical Society Reviews. 40: 4217-31. PMID 21566810 DOI: 10.1039/C1Cs15022G |
0.747 |
|
2010 |
Kolstoe SE, Mangione PP, Bellotti V, Taylor GW, Tennent GA, Deroo S, Morrison AJ, Cobb AJ, Coyne A, McCammon MG, Warner TD, Mitchell J, Gill R, Smith MD, Ley SV, et al. Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proceedings of the National Academy of Sciences of the United States of America. 107: 20483-8. PMID 21059958 DOI: 10.1073/Pnas.1008255107 |
0.652 |
|
2010 |
Cox DJ, Smith MD, Fairbanks AJ. Glycosylation catalyzed by a chiral Brønsted acid. Organic Letters. 12: 1452-5. PMID 20199058 DOI: 10.1021/Ol1001895 |
0.587 |
|
2009 |
Maciver EE, Thompson S, Smith MD. Catalytic asymmetric 6pi electrocyclization: enantioselective synthesis of functionalized indolines. Angewandte Chemie (International Ed. in English). 48: 9979-82. PMID 19890932 DOI: 10.1002/Anie.200905169 |
0.58 |
|
2009 |
Jones CR, Panto? GD, Morrison AJ, Smith MD. Plagiarizing proteins: enhancing efficiency in asymmetric hydrogen-bonding catalysis through positive cooperativity. Angewandte Chemie (International Ed. in English). 48: 7391-4. PMID 19728352 DOI: 10.1002/Anie.200903063 |
0.471 |
|
2009 |
Tomlin PM, Davies DJ, Smith MD. Favorskii rearrangement of a highly functionalized meso-dihaloketone Tetrahedron: Asymmetry. 20: 961-969. DOI: 10.1016/J.Tetasy.2009.03.020 |
0.376 |
|
2008 |
Jones CR, Qureshi MK, Truscott FR, Hsu ST, Morrison AJ, Smith MD. A nonpeptidic reverse turn that promotes parallel sheet structure stabilized by C-H...O hydrogen bonds in a cyclopropane gamma-peptide. Angewandte Chemie (International Ed. in English). 47: 7099-102. PMID 18666304 DOI: 10.1002/Anie.200802648 |
0.459 |
|
2007 |
Andrews SP, Ball M, Wierschem F, Cleator E, Oliver S, Högenauer K, Simic O, Antonello A, Hünger U, Smith MD, Ley SV. Total synthesis of five thapsigargins: guaianolide natural products exhibiting sub-nanomolar SERCA inhibition. Chemistry (Weinheim An Der Bergstrasse, Germany). 13: 5688-712. PMID 17508363 DOI: 10.1002/Chem.200700302 |
0.433 |
|
2007 |
Ball M, Andrews SP, Wierschem F, Cleator E, Smith MD, Ley SV. Total synthesis of thapsigargin, a potent SERCA pump inhibitor. Organic Letters. 9: 663-6. PMID 17256950 DOI: 10.1021/Ol062947X |
0.401 |
|
2007 |
Andrews SP, Ball M, Wierschem F, Cleator E, Oliver S, Högenauer K, Simic O, Antonello A, Hünger U, Smith MD, Ley SV. Synthesis of Thapsigargin Synfacts. 2007: 1229-1229. DOI: 10.1055/S-2007-991303 |
0.451 |
|
2007 |
Andrews S, Ball M, Wierschem F, Cleator E, Oliver S, Högenauer K, Simic O, Antonello A, Hünger U, Smith M, Ley S. Cover Picture: Total Synthesis of Five Thapsigargins: Guaianolide Natural Products Exhibiting Sub-Nanomolar SERCA Inhibition (Chem. Eur. J. 20/2007) Chemistry - a European Journal. 13: 5657-5657. DOI: 10.1002/Chem.200790070 |
0.413 |
|
2006 |
Pepys MB, Hirschfield GM, Tennent GA, Gallimore JR, Kahan MC, Bellotti V, Hawkins PN, Myers RM, Smith MD, Polara A, Cobb AJ, Ley SV, Aquilina JA, Robinson CV, Sharif I, et al. Targeting C-reactive protein for the treatment of cardiovascular disease. Nature. 440: 1217-21. PMID 16642000 DOI: 10.1038/Nature04672 |
0.683 |
|
2005 |
Søhoel H, Liljefors T, Ley SV, Oliver SF, Antonello A, Smith MD, Olsen CE, Isaacs JT, Christensen SB. Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase inhibitors designed by an analysis of the binding site of thapsigargin. Journal of Medicinal Chemistry. 48: 7005-11. PMID 16250659 DOI: 10.1021/Jm058036V |
0.396 |
|
2005 |
Brittain DE, Griffiths-Jones CM, Linder MR, Smith MD, McCusker C, Barlow JS, Akiyama R, Yasuda K, Ley SV. Total synthesis of antascomicin B. Angewandte Chemie (International Ed. in English). 44: 2732-7. PMID 15806607 DOI: 10.1002/Anie.200500174 |
0.395 |
|
2005 |
Claridge TD, Long DD, Baker CM, Odell B, Grant GH, Edwards AA, Tranter GE, Fleet GW, Smith MD. Helix-forming carbohydrate amino acids. The Journal of Organic Chemistry. 70: 2082-90. PMID 15760191 DOI: 10.1021/Jo0480040 |
0.544 |
|
2005 |
Lohmann S, Andrews SP, Burke BJ, Smith MD, Attfield JP, Tanaka H, Kaneko K, Ley SV. Copper- and palladium-containing perovskites: Catalysts for the Ullmann and Sonogashira reactions Synlett. 1291-1295. DOI: 10.1055/S-2005-865233 |
0.463 |
|
2005 |
Lohmann S, Andrews SP, Burke BJ, Smith MD, Attfield JP, Tanaka H, Kaneko K, Ley SV. Copper- and Palladium-Containing Perovskites: Catalysts for the Ullmann and Sonogashira Reactions. Cheminform. 36. DOI: 10.1002/chin.200542090 |
0.372 |
|
2005 |
Andrews SP, Stepan AF, Tanaka H, Ley SV, Smith MD. Heterogeneous or homogeneous? A case study involving palladium-containing perovskites in the Suzuki reaction Advanced Synthesis and Catalysis. 347: 647-654. DOI: 10.1002/Adsc.200404331 |
0.461 |
|
2004 |
Lemmon MT, Wolff MJ, Smith MD, Clancy RT, Banfield D, Landis GA, Ghosh A, Smith PH, Spanovich N, Whitney B, Whelley P, Greeley R, Thompson S, Bell JF, Squyres SW. Atmospheric imaging results from the Mars exploration rovers: Spirit and Opportunity. Science (New York, N.Y.). 306: 1753-6. PMID 15576613 DOI: 10.1126/Science.1104474 |
0.373 |
|
2004 |
Ley SV, Antonello A, Balskus EP, Booth DT, Christensen SB, Cleator E, Gold H, Högenauer K, Hünger U, Myers RM, Oliver SF, Simic O, Smith MD, Søhoel H, Woolford AJ. Synthesis of the thapsigargins. Proceedings of the National Academy of Sciences of the United States of America. 101: 12073-8. PMID 15226504 DOI: 10.1073/Pnas.0403300101 |
0.742 |
|
2003 |
Oliver SF, Högenauer K, Simic O, Antonello A, Smith MD, Ley SV. A route to the thapsigargins from (S)-carvone providing a substrate-controlled total synthesis of trilobolide, nortrilobolide, and thapsivillosin F. Angewandte Chemie (International Ed. in English). 42: 5996-6000. PMID 14679553 DOI: 10.1002/Anie.200353140 |
0.395 |
|
2003 |
Smith MD, Claridge TD, Sansom MS, Fleet GW. Bend ribbon-forming tetrahydrofuran amino acids. Organic & Biomolecular Chemistry. 1: 3647-55. PMID 14649895 DOI: 10.1039/B307707C |
0.533 |
|
2003 |
Smith MD, Stepan AF, Ramarao C, Brennan PE, Ley SV. Palladium-containing perovskites: recoverable and reuseable catalysts for Suzuki couplings. Chemical Communications (Cambridge, England). 2652-3. PMID 14649794 DOI: 10.1039/B308465E |
0.529 |
|
2003 |
Hirschfield GM, Smith MD, Ley SV, Kolstoe S, Thompson D, Wood SP, Pepys MB. Therapeutic Inhibition of C-Reactive Protein-Novel Drugs, Novel Mechanisms Clinical Science. 104. DOI: 10.1042/Cs104065Pb |
0.376 |
|
2003 |
Long DD, Smith MD, Martin A, Wheatley JR, Watkin DG, Mueller M, Fleet GWJ. Complex Tetrahydrofurans from Carbohydrate Lactones: THF Amino Acids as Building Blocks for Unnatural Biopolymers. Cheminform. 34. DOI: 10.1039/B111258A |
0.322 |
|
2003 |
Watterson MP, Edwards AA, Leach JA, Smith MD, Ichihara O, Fleet GWJ. Synthesis of all diastereomeric methyl 2,5-anhydro-3-deoxy-hexonates: Precursors to C-2-deoxynucleosides and THF-templated γ- and δ-amino acids Tetrahedron Letters. 44: 5853-5857. DOI: 10.1016/S0040-4039(03)01416-3 |
0.308 |
|
2002 |
Ley SV, Ramarao C, Gordon RS, Holmes AB, Morrison AJ, McConvey IF, Shirley IM, Smith SC, Smith MD. Polyurea-encapsulated palladium(II) acetate: a robust and recyclable catalyst for use in conventional and supercritical media. Chemical Communications (Cambridge, England). 1134-5. PMID 12122701 DOI: 10.1039/B200677B |
0.446 |
|
2001 |
Ley SV, Ramarao C, Smith MD. Tetra-N-propylammonium perruthenate: a case study in catalyst recovery and re-use involving tetraalkylammonium salts. Chemical Communications (Cambridge, England). 2278-9. PMID 12240149 DOI: 10.1039/B107966M |
0.419 |
|
2001 |
Long DD, Tennant-Eyles RJ, Estevez JC, Wormald MR, Dwek RA, Smith MD, Fleet GWJ. Carbopeptoids: peptides and diketopiperazines incorporating the anomeric centre of mannopyranose Journal of the Chemical Society-Perkin Transactions 1. 807-813. DOI: 10.1039/B009940F |
0.327 |
|
2000 |
Brittain DEA, Watterson MP, Claridge TDW, Smith MD, Fleet GWJ. Tetrahydrofuran amino acids—versatile building blocks for unnatural biopolymers: lack of secondary structure in oligomeric carbopeptoids derived from a D-galacto-5-(aminomethyl) tetrahydrofuran-2-carboxylic acid Journal of the Chemical Society-Perkin Transactions 1. 3655-3665. DOI: 10.1039/B002995P |
0.315 |
|
1999 |
Smith MD, Fleet GW. Designing secondary structures: 5-azidomethyl tetrahydrofuran-2-carboxylates as carbohydrate-derived dipeptide isosteres. Journal of Peptide Science : An Official Publication of the European Peptide Society. 5: 425-41. PMID 10580642 DOI: 10.1002/(Sici)1099-1387(199910)5:10<425::Aid-Psc222>3.0.Co;2-O |
0.518 |
|
1999 |
Watterson MP, Pickering L, Smith MD, Hudson SJ, Marsh PR, Mordaunt JE, Watkin DJ, Newman CJ, Fleet GW. 3-Azidotetrahydrofuran-2-carboxylates: monomers for five-ring templated β-amino acid foldamers? Tetrahedron: Asymmetry. 10: 1855-1859. DOI: 10.1016/S0957-4166(99)00205-0 |
0.526 |
|
1999 |
Lee RE, Smith MD, Pickering L, Fleet GW. An approach to combinatorial library generation of galactofuranose mimics as potential inhibitors of mycobacterial cell wall biosynthesis: Synthesis of a peptidomimetic of uridine 5′-diphosphogalactofuranose (UDP-Galf) Tetrahedron Letters. 40: 8689-8692. DOI: 10.1016/S0040-4039(99)01844-4 |
0.532 |
|
1999 |
Claridge TDW, Long DD, Hungerford NL, Aplin RT, Smith MD, Marquess DG, Fleet GWJ. An octameric carbopeptoid; secondary structure in octameric and tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates Tetrahedron Letters. 40: 2199-2202. DOI: 10.1016/S0040-4039(99)00111-2 |
0.301 |
|
1999 |
Smith MD, Long DD, Martín A, Marquess DG, Claridge TDW, Fleet GWJ. Absence of secondary structure in a carbopeptoid tetramer of a trans-5- aminomethyl-tetrahydrofuran-2-carboxylate Tetrahedron Letters. 40: 2191-2194. DOI: 10.1016/S0040-4039(99)00109-4 |
0.309 |
|
1998 |
Smith MD, Claridge TDW, Fleet GWJ, Tranter GE, Sansom MSP. Secondary structure in oligomers of carbohydrate amino acids Chemical Communications. 2041-2042. DOI: 10.1039/A805401K |
0.3 |
|
1998 |
Smith MD, Long DD, Claridge TDW, Fleet GWJ, Marquess DG. Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids Chemical Communications. 2039-2040. DOI: 10.1039/A805364B |
0.341 |
|
1998 |
Long DD, Smith MD, Marquess DG, Claridge TD, Fleet GW. A solid phase approach to oligomers of carbohydrate amino-acids: Secondary structure in a trimeric furanose carbopeptoid Tetrahedron Letters. 39: 9293-9296. DOI: 10.1016/S0040-4039(98)02089-9 |
0.557 |
|
1996 |
Estevez JC, Smith MD, Wormald MR, Besra GS, Brennan PJ, Nash RJ, Fleet GWJ. Mimics of L-rhamnose: Analogues of rhamnopyranose containing a constituent α-amino acid at the anomeric position. A rhamnopyranose analogue of hydantocidin Tetrahedron Asymmetry. 7: 391-394. DOI: 10.1016/0957-4166(96)00014-6 |
0.302 |
|
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