Steven Victor Ley, Ph.D. - Publications

Affiliations: 
Chemsitry University of Cambridge, Cambridge, England, United Kingdom 
Area:
Organic Chemistry, Total Synthesis, Flow Chemistry
Website:
http://www.leygroup.ch.cam.ac.uk

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Year Citation  Score
2020 Pastre JC, Murray PRD, Browne DL, Brancaglion GA, Galaverna RS, Pilli RA, Ley SV. Integrated Batch and Continuous Flow Process for the Synthesis of Goniothalamin. Acs Omega. 5: 18472-18483. PMID 32743225 DOI: 10.1021/acsomega.0c02390  0.651
2020 Cao L, Kabeshov M, Ley SV, Lapkin AA. In silico rationalisation of selectivity and reactivity in Pd-catalysed C-H activation reactions. Beilstein Journal of Organic Chemistry. 16: 1465-1475. PMID 32647548 DOI: 10.3762/Bjoc.16.122  0.346
2020 Fitzpatrick DE, O'Brien M, Ley SV. A tutored discourse on microcontrollers, single board computers and their applications to monitor and control chemical reactions Reaction Chemistry & Engineering. 5: 201-220. DOI: 10.1039/C9Re00407F  0.716
2020 Ley SV, Chen Y, Fitzpatrick DE, May OS. Living with our machines: Towards a more sustainable future Current Opinion in Green and Sustainable Chemistry. 25: 100353. DOI: 10.1016/J.Cogsc.2020.100353  0.732
2019 Watanabe E, Chen Y, May O, Ley SV. A Practical Method for Continuous Production of sp3-Rich Compounds from (Hetero)Aryl Halides and Redox-Active Esters. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31692149 DOI: 10.1002/Chem.201905048  0.396
2019 Lopatka P, Markovič M, Koóš P, Ley SV, Gracza T. Continuous Pd-Catalyzed Carbonylative Cyclization Using Iron Pentacarbonyl as a CO Source. The Journal of Organic Chemistry. PMID 31646860 DOI: 10.1021/Acs.Joc.9B02453  0.343
2019 Ley SV, Chen Y, Fitzpatrick DE, May O. A New World for Chemical Synthesis? Chimia. 73: 792-802. PMID 31645239 DOI: 10.2533/Chimia.2019.792  0.716
2019 Chen Y, May O, Blakemore DC, Ley SV. A Photoredox Coupling Reaction of Benzylboronic Esters and Carbonyl Compounds in Batch and Flow. Organic Letters. PMID 31335152 DOI: 10.1021/Acs.Orglett.9B02307  0.397
2019 Grainger R, Heightman TD, Ley SV, Lima F, Johnson CN. Enabling synthesis in fragment-based drug discovery by reactivity mapping: photoredox-mediated cross-dehydrogenative heteroarylation of cyclic amines. Chemical Science. 10: 2264-2271. PMID 30881651 DOI: 10.1039/C8Sc04789H  0.629
2019 Dixon DJ, Foster AC, Ley SV. A short and efficient stereoselective synthesis of the polyhydroxylated macrolactone (+)-aspicillin Organic Letters. 2: 123-5. PMID 10814262 DOI: 10.1021/Ol991214S  0.58
2019 Labes R, Mateos C, Battilocchio C, Chen Y, Dingwall P, Cumming GR, Rincón JA, Nieves-Remacha MJ, Ley SV. Fast continuous alcohol amination employing a hydrogen borrowing protocol Green Chemistry. 21: 59-63. DOI: 10.1039/C8Gc03328E  0.646
2018 Lesieur M, Battilocchio C, Labes R, Jacq J, Genicot C, Ley SV, Pasau P. Direct Oxidation of Csp -H bonds using in Situ Generated Trifluoromethylated Dioxirane in Flow. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30485562 DOI: 10.1002/Chem.201805657  0.665
2018 Chen Y, Leonardi M, Dingwall P, Labes R, Pasau P, Blakemore DC, Ley SV. Photochemical homologation for the preparation of aliphatic aldehydes in flow. The Journal of Organic Chemistry. PMID 30444967 DOI: 10.1021/Acs.Joc.8B02721  0.391
2018 Fitzpatrick DE, Maujean T, Evans A, Ley SV. Across-the-world automated optimization and continuous flow synthesis of pharmaceutical agents operating through a cloud-based server. Angewandte Chemie (International Ed. in English). PMID 30272384 DOI: 10.1002/Anie.201809080  0.723
2018 Chen Y, Blakemore DC, Pasau P, Ley SV. Three-Component Assembly of Multiply Substituted Homoallylic Alcohols and Amines Using a Flow Chemistry Photoreactor. Organic Letters. PMID 30270627 DOI: 10.1021/Acs.Orglett.8B02907  0.353
2018 Dingwall P, Greb A, Crespin LNS, Labes R, Musio B, Poh JS, Pasau P, Blakemore DC, Ley SV. C-H functionalisation of aldehydes using light generated, non-stabilised diazo compounds in flow. Chemical Communications (Cambridge, England). PMID 30203830 DOI: 10.1039/C8Cc06202A  0.398
2018 Ou X, Labes R, Battilocchio C, Ley SV. Preparation of homoallylic amines via a three-component coupling process. Organic & Biomolecular Chemistry. PMID 30183047 DOI: 10.1039/C8Ob01831F  0.719
2018 Lima F, Grunenberg L, Rahman HBA, Labes R, Sedelmeier J, Ley SV. Organic photocatalysis for the radical couplings of boronic acid derivatives in batch and flow. Chemical Communications (Cambridge, England). PMID 29767201 DOI: 10.1039/C8Cc02169D  0.619
2018 Ritson DJ, Battilocchio C, Ley SV, Sutherland JD. Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry. Nature Communications. 9: 1821. PMID 29739945 DOI: 10.1038/S41467-018-04147-2  0.691
2018 Ley SV. The Engineering of Chemical Synthesis: Humans and Machines Working in Harmony. Angewandte Chemie (International Ed. in English). PMID 29603525 DOI: 10.1002/Anie.201802383  0.308
2018 Fitzpatrick DE, Mutton RJ, Ley SV. In-line separation of multicomponent reaction mixtures using a new semi-continuous supercritical fluid chromatography system Reaction Chemistry & Engineering. 3: 799-806. DOI: 10.1039/C8Re00107C  0.705
2018 Scott CD, Labes R, Depardieu M, Battilocchio C, Davidson MG, Ley SV, Wilson CC, Robertson K. Integrated plug flow synthesis and crystallisation of pyrazinamide Reaction Chemistry & Engineering. 3: 631-634. DOI: 10.1039/C8Re00087E  0.689
2018 Godineau E, Battilocchio C, Lehmann M, Ley SV, Labes R, Birnoschi L, Subramanian S, Prasanna CS, Gorde A, Kalbagh M, Khade V, Scherrer A, O’Sullivan AC. A Convergent Continuous Multistep Process for the Preparation of C4-Oxime-Substituted Thiazoles Organic Process Research & Development. 22: 955-962. DOI: 10.1021/Acs.Oprd.8B00095  0.687
2018 O'Brien M, Weber A, Hardy G, Ley SV. Highly diastereoselective boron and titanium mediated aldol reactions of a mannitol derived 2,3-butanediacetal ethyl ketone Tetrahedron. 74: 5319-5329. DOI: 10.1016/J.Tet.2018.06.041  0.399
2018 Fitzpatrick D, Ley S. Engineering chemistry for the future of chemical synthesis Tetrahedron. 74: 3087-3100. DOI: 10.1016/J.Tet.2017.08.050  0.683
2018 Ley SV. Editorial: Harmonische Zusammenarbeit von Mensch und Maschine in der chemischen Synthese Angewandte Chemie. 130: 5278-5279. DOI: 10.1002/Ange.201802383  0.312
2017 Bomio C, Kabeshov MA, Lit AR, Lau SH, Ehlert J, Battilocchio C, Ley SV. Unveiling the role of boroxines in metal-free carbon-carbon homologations using diazo compounds and boronic acids. Chemical Science. 8: 6071-6075. PMID 29619197 DOI: 10.1039/C7Sc02264F  0.78
2017 Crespin LNS, Greb A, Blakemore DC, Ley SV. Visible-Light-Mediated Annulation of Electron-Rich Alkenes and Nitrogen-Centered Radicals from N-Sulfonylallylamines: Construction of Chloromethylated Pyrrolidine Derivatives. The Journal of Organic Chemistry. PMID 29121471 DOI: 10.1021/Acs.Joc.7B02146  0.309
2017 Greb A, Poh JS, Greed S, Battilocchio C, Pasau P, Blakemore DC, Ley SV. A New Versatile Route to Unstable Diazo Compounds via Oxadiazolines and Use In Aryl-Alkyl Cross-Coupling Reactions. Angewandte Chemie (International Ed. in English). PMID 29088512 DOI: 10.1002/Anie.201710445  0.703
2017 Lima F, Sharma UK, Grunenberg L, Saha D, Johannsen S, Sedelmeier J, Van der Eycken EV, Ley SV. A Lewis Base Catalysis Approach for the Photoredox Activation of Boronic Acids and Esters. Angewandte Chemie (International Ed. in English). PMID 29024307 DOI: 10.1002/Anie.201709690  0.612
2017 Crespin L, Biancalana L, Morack T, Blakemore DC, Ley SV. One-Pot Acid-Catalyzed Ring-Opening/Cyclization/Oxidation of Aziridines with N-Tosylhydrazones: Access to 1,2,4-Triazines. Organic Letters. PMID 28199120 DOI: 10.1021/Acs.Orglett.7B00101  0.411
2017 Poh JS, Makai S, von Keutz T, Tran DN, Battilocchio C, Pasau P, Ley SV. Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow-Generated Diazo Compounds and Propargylated Amines. Angewandte Chemie (International Ed. in English). PMID 28075518 DOI: 10.1002/Anie.201611067  0.726
2017 Ley S, Pastre J, Forni J, Lau S, Poh J, Battilocchio C. Diastereoselective Synthesis of Functionalized Indolines Using in situ Generated Allyl Boronic Species Synlett. 29: 825-829. DOI: 10.1055/S-0036-1589164  0.717
2017 Labes R, González-Calderón D, Battilocchio C, Mateos C, Cumming G, de Frutos O, Rincón J, Ley S. Rapid Continuous Ruthenium-Catalysed Transfer Hydrogenation of Aromatic Nitriles to Primary Amines Synlett. 28: 2855-2858. DOI: 10.1055/S-0036-1589096  0.679
2017 Kabeshov MA, Musio B, Ley SV. Continuous direct anodic flow oxidation of aromatic hydrocarbons to benzyl amides Reaction Chemistry & Engineering. 2: 822-825. DOI: 10.1039/C7Re00164A  0.335
2017 Battilocchio C, Iannucci G, Wang S, Godineau E, Kolleth A, De Mesmaeker A, Ley SV. Flow synthesis of cyclobutanones via [2 + 2] cycloaddition of keteneiminium salts and ethylene gas Reaction Chemistry & Engineering. 2: 295-298. DOI: 10.1039/C7Re00020K  0.699
2017 Musio B, Gala E, Ley SV. Real-Time Spectroscopic Analysis Enabling Quantitative and Safe Consumption of Fluoroform during Nucleophilic Trifluoromethylation in Flow Acs Sustainable Chemistry & Engineering. 6: 1489-1495. DOI: 10.1021/Acssuschemeng.7B04012  0.334
2017 Battilocchio C, Bosica F, Rowe SM, Abreu BL, Godineau E, Lehmann M, Ley SV. Continuous Preparation and Use of Dibromoformaldoxime as a Reactive Intermediate for the Synthesis of 3-Bromoisoxazolines Organic Process Research & Development. 21: 1588-1594. DOI: 10.1021/Acs.Oprd.7B00229  0.701
2017 Labes R, Battilocchio C, Mateos C, Cumming GR, de Frutos O, Rincón JA, Binder K, Ley SV. Chemoselective Continuous Ru-Catalyzed Hydrogen-Transfer Oppenauer-Type Oxidation of Secondary Alcohols Organic Process Research & Development. 21: 1419-1422. DOI: 10.1021/Acs.Oprd.7B00190  0.658
2017 Mohapatra SS, Wilson ZE, Roy S, Ley SV. Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis(indolyl)methanes Tetrahedron. 73: 1812-1819. DOI: 10.1016/J.Tet.2017.02.026  0.445
2016 Poh JS, Lau SH, Dykes IG, Tran DN, Battilocchio C, Ley SV. A multicomponent approach for the preparation of homoallylic alcohols. Chemical Science. 7: 6803-6807. PMID 28042466 DOI: 10.1039/C6Sc02581A  0.775
2016 Lima F, Kabeshov MA, Tran DN, Battilocchio C, Sedelmeier J, Sedelmeier G, Schenkel B, Ley SV. Visible Light Activation of Boronic Esters Enables Efficient Photoredox C(sp(2) )-C(sp(3) ) Cross-Couplings in Flow. Angewandte Chemie (International Ed. in English). PMID 27709749 DOI: 10.1002/Anie.201605548  0.752
2016 Fenner S, Wilson ZE, Ley SV. The Total Synthesis of the Bioactive Natural Product Plantazolicin A and Its Biosynthetic Precursor Plantazolicin B. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27619732 DOI: 10.1002/Chem.201603157  0.399
2016 Movsisyan M, Delbeke EI, Berton JK, Battilocchio C, Ley SV, Stevens CV. Taming hazardous chemistry by continuous flow technology. Chemical Society Reviews. PMID 27453961 DOI: 10.1039/C5Cs00902B  0.681
2016 Poh JS, Browne DL, Ley SV. A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process. Reaction Chemistry & Engineering. 1: 101-105. PMID 27398231 DOI: 10.1039/C5Re00082C  0.66
2016 Poh JS, García-Ruiz C, Zúñiga A, Meroni F, Blakemore DC, Browne DL, Ley SV. Synthesis of trifluoromethylated isoxazoles and their elaboration through inter- and intra-molecular C-H arylation. Organic & Biomolecular Chemistry. PMID 27225313 DOI: 10.1039/C6Ob00970K  0.675
2016 Fitzpatrick DE, Battilocchio C, Ley SV. Enabling Technologies for the Future of Chemical Synthesis. Acs Central Science. 2: 131-8. PMID 27163040 DOI: 10.1021/Acscentsci.6B00015  0.781
2016 Battilocchio C, Feist F, Hafner A, Simon M, Tran DN, Allwood DM, Blakemore DC, Ley SV. Iterative reactions of transient boronic acids enable sequential C-C bond formation. Nature Chemistry. 8: 360-7. PMID 27001732 DOI: 10.1038/Nchem.2439  0.79
2016 Lücke D, Dalton T, Ley SV, Wilson ZE. Synthesis of Natural and Unnatural Cyclooligomeric Depsipeptides Enabled by Flow Chemistry. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26844421 DOI: 10.1002/Chem.201504457  0.424
2016 Sutherell C, Ley S. On the Synthesis and Reactivity of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-ones Synthesis. 49: 135-144. DOI: 10.1055/S-0035-1562792  0.386
2016 Ley S, Musio B, Mariani F, Śliwiński E, Kabeshov M, Odajima H. Combination of Enabling Technologies to Improve and Describe the Stereoselectivity of Wolff–Staudinger Cascade Reaction Synthesis. 48: 3515-3526. DOI: 10.1055/S-0035-1562579  0.361
2016 Snieckus V, Miranzadeh M, Poh J-, García-Ruiz C, Zúñiga A, Meroni F, Blakemore DC, Browne DL, Ley SV. Synthesis of Trifluoromethylated Isoxazoles by [2+3] Cycloaddition Synfacts. 12: 900-900. DOI: 10.1055/S-0035-1562575  0.721
2016 Brahma A, Musio B, Ismayilova U, Nikbin N, Kamptmann SB, Siegert P, Jeromin GE, Ley SV, Pohl M. An orthogonal biocatalytic approach for the safe generation and use of HCN in a multistep continuous preparation of chiral O-acetylcyanohydrins Synlett. 27: 262-266. DOI: 10.1055/S-0035-1560644  0.344
2016 Fitzpatrick DE, Ley SV. Engineering chemistry: integrating batch and flow reactions on a single, automated reactor platform Reaction Chemistry & Engineering. 1: 629-635. DOI: 10.1039/C6Re00160B  0.737
2016 Ouchi T, Mutton RJ, Rojas V, Fitzpatrick DE, Cork DG, Battilocchio C, Ley SV. Solvent-Free Continuous Operations Using Small Footprint Reactors: A Key Approach for Process Intensification Acs Sustainable Chemistry and Engineering. 4: 1912-1916. DOI: 10.1021/Acssuschemeng.6B00287  0.794
2016 Ahmed-Omer B, Sliwinski E, Cerroti JP, Ley SV. Continuous Processing and Efficientin SituReaction Monitoring of a Hypervalent Iodine(III) Mediated Cyclopropanation Using Benchtop NMR Spectroscopy Organic Process Research & Development. 20: 1603-1614. DOI: 10.1021/Acs.Oprd.6B00177  0.78
2015 Tran DN, Battilocchio C, Lou SB, Hawkins JM, Ley SV. Flow chemistry as a discovery tool to access sp-spcross-coupling reactionsdiazo compounds. Chemical Science. 6: 1120-1125. PMID 29560199 DOI: 10.1039/C4Sc03072A  0.689
2015 Lau SH, Bourne SL, Martin B, Schenkel B, Penn G, Ley SV. Synthesis of a Precursor to Sacubitril Using Enabling Technologies. Organic Letters. 17: 5436-9. PMID 26509957 DOI: 10.1021/Acs.Orglett.5B02806  0.809
2015 Briggs ME, Slater AG, Lunt N, Jiang S, Little MA, Greenaway RL, Hasell T, Battilocchio C, Ley SV, Cooper AI. Dynamic flow synthesis of porous organic cages. Chemical Communications (Cambridge, England). PMID 26463103 DOI: 10.1039/C5Cc07447A  0.685
2015 Schotten C, Plaza D, Manzini S, Nolan SP, Ley SV, Browne DL, Lapkin A. Continuous Flow Metathesis for Direct Valorization of Food Waste: An Example of Cocoa Butter Triglyceride. Acs Sustainable Chemistry & Engineering. 3: 1453-1459. PMID 26322250 DOI: 10.1021/Acssuschemeng.5B00397  0.624
2015 Frost JR, Pearson CM, Snaddon TN, Booth RA, Turner RM, Gold J, Shaw DM, Gaunt MJ, Ley SV. Callipeltosides A, B and C: Total Syntheses and Structural Confirmation. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 13261-77. PMID 26230615 DOI: 10.1002/Chem.201501877  0.772
2015 De Lucia D, Lucio OM, Musio B, Bender A, Listing M, Dennhardt S, Koeberle A, Garscha U, Rizzo R, Manfredini S, Werz O, Ley SV. Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors. European Journal of Medicinal Chemistry. 101: 573-83. PMID 26197161 DOI: 10.1016/J.Ejmech.2015.07.011  0.325
2015 Ley SV, Fitzpatrick DE, Myers RM, Battilocchio C, Ingham RJ. Machine-Assisted Organic Synthesis. Angewandte Chemie (International Ed. in English). 54: 10122-36. PMID 26193360 DOI: 10.1002/Anie.201501618  0.784
2015 Lau SH, Galván A, Merchant RR, Battilocchio C, Souto JA, Berry MB, Ley SV. Machines vs Malaria: A Flow-Based Preparation of the Drug Candidate OZ439. Organic Letters. 17: 3218-21. PMID 26079282 DOI: 10.1021/Acs.Orglett.5B01307  0.772
2015 Poh JS, Tran DN, Battilocchio C, Hawkins JM, Ley SV. A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo Compounds. Angewandte Chemie (International Ed. in English). 54: 7920-3. PMID 26013774 DOI: 10.1002/Anie.201501538  0.702
2015 Alves LC, Desiderá AL, de Oliveira KT, Newton S, Ley SV, Brocksom TJ. A practical deca-gram scale ring expansion of (R)-(-)-carvone to (R)-(+)-3-methyl-6-isopropenyl-cyclohept-3-enone-1. Organic & Biomolecular Chemistry. PMID 25997609 DOI: 10.1039/C5Ob00525F  0.309
2015 Rouquet G, Moore DE, Spain M, Allwood DM, Battilocchio C, Blakemore DC, Fish PV, Jenkinson S, Jessiman AS, Ley SV, McMurray G, Storer RI. Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists. Acs Medicinal Chemistry Letters. 6: 329-33. PMID 25815155 DOI: 10.1021/Ml500507V  0.781
2015 Kabeshov MA, Sliwiński É, Fitzpatrick DE, Musio B, Newby JA, Blaylock WD, Ley SV. Development of a web-based platform for studying lithiation reactions in silico. Chemical Communications (Cambridge, England). 51: 7172-5. PMID 25811168 DOI: 10.1039/C5Cc00782H  0.776
2015 Souto JA, Stockman RA, Ley SV. Development of a flow method for the hydroboration/oxidation of olefins. Organic & Biomolecular Chemistry. 13: 3871-7. PMID 25714697 DOI: 10.1039/C5Ob00170F  0.306
2015 Brzozowski M, O'Brien M, Ley SV, Polyzos A. Flow chemistry: intelligent processing of gas-liquid transformations using a tube-in-tube reactor. Accounts of Chemical Research. 48: 349-62. PMID 25611216 DOI: 10.1021/Ar500359M  0.688
2015 Roda NM, Tran DN, Battilocchio C, Labes R, Ingham RJ, Hawkins JM, Ley SV. Cyclopropanation using flow-generated diazo compounds. Organic & Biomolecular Chemistry. 13: 2550-4. PMID 25600950 DOI: 10.1039/C5Ob00019J  0.677
2015 Ley SV, Fitzpatrick DE, Ingham RJ, Myers RM. Organic synthesis: march of the machines. Angewandte Chemie (International Ed. in English). 54: 3449-64. PMID 25586940 DOI: 10.1002/Anie.201410744  0.784
2015 Wilson ZE, Fenner S, Ley SV. Total syntheses of linear polythiazole/oxazole plantazolicin A and its biosynthetic precursor plantazolicin B. Angewandte Chemie (International Ed. in English). 54: 1284-8. PMID 25424526 DOI: 10.1002/Anie.201410063  0.386
2015 Ingham RJ, Battilocchio C, Fitzpatrick DE, Sliwinski E, Hawkins JM, Ley SV. A systems approach towards an intelligent and self-controlling platform for integrated continuous reaction sequences. Angewandte Chemie (International Ed. in English). 54: 144-8. PMID 25377747 DOI: 10.1002/Anie.201409356  0.79
2015 Glöckner S, Tran DN, Ingham RJ, Fenner S, Wilson ZE, Battilocchio C, Ley SV. The rapid synthesis of oxazolines and their heterogeneous oxidation to oxazoles under flow conditions. Organic & Biomolecular Chemistry. 13: 207-14. PMID 25370905 DOI: 10.1039/C4Ob02105C  0.692
2015 Kamptmann SB, Ley SV. Facilitating biomimetic syntheses of borrerine derived alkaloids by means of flow-chemical methods Australian Journal of Chemistry. 68: 693-696. DOI: 10.1071/Ch14530  0.399
2015 Hafner A, Ley SV. Generation of Reactive Ketenes under Flow Conditions through Zinc-Mediated Dehalogenation Synlett. 26: 1470-1474. DOI: 10.1055/S-0034-1380679  0.351
2015 Tran DN, Battilocchio C, Lou SB, Hawkins JM, Ley SV. Flow chemistry as a discovery tool to access sp2-sp3 cross-coupling reactions via diazo compounds Chemical Science. 6: 1120-1125. DOI: 10.1039/c4sc03072a  0.655
2015 Schotten C, Plaza D, Manzini S, Nolan SP, Ley SV, Browne DL, Lapkin A. Continuous Flow Metathesis for Direct Valorization of Food Waste: An Example of Cocoa Butter Triglyceride Acs Sustainable Chemistry and Engineering. 3: 1453-1459. DOI: 10.1021/acssuschemeng.5b00397  0.552
2015 Fitzpatrick DE, Battilocchio C, Ley SV. A Novel Internet-Based Reaction Monitoring, Control and Autonomous Self-Optimization Platform for Chemical Synthesis Organic Process Research & Development. 20: 386-394. DOI: 10.1021/Acs.Oprd.5B00313  0.788
2015 de Lucia D, Lucio OM, Musio B, Bender A, Listing M, Dennhardt S, Koeberle A, Garscha U, Rizzo R, Manfredini S, Werz O, Ley SV. Corrigendum to “Design, synthesis and evaluation of semi-synthetic triazole-containing caffeic acid analogues as 5-lipoxygenase inhibitors” [Eur. J. Med. Chem. 101 (2015) 573–583] European Journal of Medicinal Chemistry. 103: 223-225. DOI: 10.1016/J.Ejmech.2015.08.050  0.363
2015 Frost JR, Pearson CM, Snaddon TN, Booth RA, Turner RM, Gold J, Shaw DM, Gaunt MJ, Ley SV. Back Cover: Callipeltosides A, B and C: Total Syntheses and Structural Confirmation (Chem. Eur. J. 38/2015) Chemistry - a European Journal. 21: 13464-13464. DOI: 10.1002/Chem.201583804  0.745
2015 Frost JR, Pearson CM, Snaddon TN, Booth RA, Turner RM, Gold J, Shaw DM, Gaunt MJ, Ley SV. Callipeltosides A, B and C: Total Syntheses and Structural Confirmation Chemistry - a European Journal. DOI: 10.1002/chem.201501877  0.73
2015 Deadman BJ, Browne DL, Baxendale IR, Ley SV. Back pressure regulation of slurry-forming reactions in continuous flow Chemical Engineering and Technology. 38: 259-264. DOI: 10.1002/Ceat.201400445  0.629
2015 Ley SV, Fitzpatrick DE, Myers RM, Battilocchio C, Ingham RJ. Maschinengestützte organische Synthese Angewandte Chemie. 127: 10260-10275. DOI: 10.1002/Ange.201501618  0.794
2015 Ley SV, Fitzpatrick DE, Ingham RJ, Myers RM. Organische Synthese: Vormarsch der Maschinen Angewandte Chemie. 127: 3514-3530. DOI: 10.1002/Ange.201410744  0.794
2014 Myers RM, Fitzpatrick DE, Turner RM, Ley SV. Flow chemistry meets advanced functional materials. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 12348-66. PMID 25156609 DOI: 10.1002/Chem.201402801  0.788
2014 Merchant RR, Allwood DM, Blakemore DC, Ley SV. Regioselective preparation of saturated spirocyclic and ring-expanded fused pyrazoles. The Journal of Organic Chemistry. 79: 8800-11. PMID 25148419 DOI: 10.1021/Jo501624T  0.807
2014 Kabeshov MA, Musio B, Murray PR, Browne DL, Ley SV. Expedient preparation of nazlinine and a small library of indole alkaloids using flow electrochemistry as an enabling technology. Organic Letters. 16: 4618-21. PMID 25147957 DOI: 10.1021/Ol502201D  0.641
2014 Baumann M, Baxendale IR, Hornung CH, Ley SV, Rojo MV, Roper KA. Synthesis of riboflavines, quinoxalinones and benzodiazepines through chemoselective flow based hydrogenations. Molecules (Basel, Switzerland). 19: 9736-59. PMID 25006783 DOI: 10.3390/Molecules19079736  0.373
2014 Rouquet G, Blakemore DC, Ley SV. Highly regioselective lithiation of pyridines bearing an oxetane unit by n-butyllithium. Chemical Communications (Cambridge, England). 50: 8908-11. PMID 24969811 DOI: 10.1039/C4Cc03766A  0.314
2014 Allwood DM, Blakemore DC, Ley SV. Preparation of unsymmetrical ketones from tosylhydrazones and aromatic aldehydes via formyl C-H bond insertion. Organic Letters. 16: 3064-7. PMID 24819872 DOI: 10.1021/Ol5011714  0.797
2014 Ingham RJ, Battilocchio C, Hawkins JM, Ley SV. Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide. Beilstein Journal of Organic Chemistry. 10: 641-52. PMID 24778715 DOI: 10.3762/Bjoc.10.56  0.668
2014 Hartwig J, Metternich JB, Nikbin N, Kirschning A, Ley SV. Continuous flow chemistry: a discovery tool for new chemical reactivity patterns. Organic & Biomolecular Chemistry. 12: 3611-5. PMID 24763674 DOI: 10.1039/C4Ob00662C  0.345
2014 Newton S, Carter CF, Pearson CM, de C Alves L, Lange H, Thansandote P, Ley SV. Accelerating spirocyclic polyketide synthesis using flow chemistry. Angewandte Chemie (International Ed. in English). 53: 4915-20. PMID 24729438 DOI: 10.1002/Anie.201402056  0.449
2014 Battilocchio C, Hawkins JM, Ley SV. Mild and selective heterogeneous catalytic hydration of nitriles to amides by flowing through manganese dioxide. Organic Letters. 16: 1060-3. PMID 24495110 DOI: 10.1021/Ol403591C  0.695
2014 Newby JA, Huck L, Blaylock DW, Witt PM, Ley SV, Browne DL. Investigation of a lithium-halogen exchange flow process for the preparation of boronates by using a cryo-flow reactor. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 263-71. PMID 24339222 DOI: 10.1002/Chem.201303736  0.652
2014 Allwood DM, Blakemore DC, Brown AD, Ley SV. Metal-free coupling of saturated heterocyclic sulfonylhydrazones with boronic acids. The Journal of Organic Chemistry. 79: 328-38. PMID 24304206 DOI: 10.1021/Jo402526Z  0.786
2014 Knudsen KR, Ladlow M, Bandpey Z, Ley SV. Fully automated sequence-specific synthesis of α-peptides using flow chemistry Journal of Flow Chemistry. 4: 18-21. DOI: 10.1556/Jfc-D-13-00033  0.376
2014 Guetzoyan L, Ingham RJ, Nikbin N, Rossignol J, Wolling M, Baumert M, Burgess-Brown NA, Strain-Damerell CM, Shrestha L, Brennan PE, Fedorov O, Knapp S, Ley SV. Machine-assisted synthesis of modulators of the histone reader BRD9 using flow methods of chemistry and frontal affinity chromatography Medchemcomm. 5: 540-546. DOI: 10.1039/C4Md00007B  0.314
2014 Newby JA, Blaylock DW, Witt PM, Turner RM, Heider PL, Harji BH, Browne DL, Ley SV. Reconfiguration of a continuous flow platform for extended operation: Application to a cryogenic fluorine-directed ortho-lithiation reaction Organic Process Research and Development. 18: 1221-1228. DOI: 10.1021/Op500221S  0.649
2014 Newby JA, Blaylock DW, Witt PM, Pastre JC, Zacharova MK, Ley SV, Browne DL. Design and application of a low-temperature continuous flow chemistry platform Organic Process Research and Development. 18: 1211-1220. DOI: 10.1021/Op500213J  0.658
2014 Ouchi T, Battilocchio C, Hawkins JM, Ley SV. Process intensification for the continuous flow hydrogenation of ethyl nicotinate Organic Process Research and Development. 18: 1560-1566. DOI: 10.1021/Op500208J  0.649
2014 Battilocchio C, Bhawal BN, Chorghade R, Deadman BJ, Hawkins JM, Ley SV. Flow-based, cerium oxide enhanced, low-level palladium sonogashira and heck coupling reactions by perovskite catalysts Israel Journal of Chemistry. 54: 371-380. DOI: 10.1002/Ijch.201300049  0.69
2014 Gross U, Koos P, O'Brien M, Polyzos A, Ley SV. A general continuous flow method for palladium catalysed carbonylation reactions using single and multiple tube-in-tube gas-liquid microreactors European Journal of Organic Chemistry. 2014: 6418-6430. DOI: 10.1002/Ejoc.201402804  0.683
2013 Battilocchio C, Guetzoyan L, Cervetto C, Di Cesare Mannelli L, Frattaroli D, Baxendale IR, Maura G, Rossi A, Sautebin L, Biava M, Ghelardini C, Marcoli M, Ley SV. Flow Synthesis and Biological Studies of an Analgesic Adamantane Derivative That Inhibits P2X7-Evoked Glutamate Release. Acs Medicinal Chemistry Letters. 4: 704-9. PMID 24900736 DOI: 10.1021/Ml400079H  0.666
2013 Watts CA, Richards FM, Bender A, Bond PJ, Korb O, Kern O, Riddick M, Owen P, Myers RM, Raff J, Gergely F, Jodrell DI, Ley SV. Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes. Chemistry & Biology. 20: 1399-410. PMID 24210220 DOI: 10.1016/J.Chembiol.2013.09.012  0.699
2013 Chorghade R, Battilocchio C, Hawkins JM, Ley SV. Sustainable flow Oppenauer oxidation of secondary benzylic alcohols with a heterogeneous zirconia catalyst. Organic Letters. 15: 5698-701. PMID 24161124 DOI: 10.1021/Ol4027107  0.646
2013 Roper KA, Berry MB, Ley SV. The application of a monolithic triphenylphosphine reagent for conducting Ramirez gem-dibromoolefination reactions in flow. Beilstein Journal of Organic Chemistry. 9: 1781-90. PMID 24062843 DOI: 10.3762/Bjoc.9.207  0.372
2013 Pastre JC, Browne DL, Ley SV. Flow chemistry syntheses of natural products. Chemical Society Reviews. 42: 8849-69. PMID 23999700 DOI: 10.1039/C3Cs60246J  0.636
2013 Ley SV, Ingham RJ, O'Brien M, Browne DL. Camera-enabled techniques for organic synthesis. Beilstein Journal of Organic Chemistry. 9: 1051-72. PMID 23766820 DOI: 10.3762/Bjoc.9.118  0.638
2013 Baxendale IR, Cheung S, Kitching MO, Ley SV, Shearman JW. The synthesis of neurotensin antagonist SR 48692 for prostate cancer research. Bioorganic & Medicinal Chemistry. 21: 4378-87. PMID 23721919 DOI: 10.1016/J.Bmc.2013.04.075  0.691
2013 Battilocchio C, Deadman BJ, Nikbin N, Kitching MO, Baxendale IR, Ley SV. A machine-assisted flow synthesis of SR48692: a probe for the investigation of neurotensin receptor-1. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 7917-30. PMID 23592596 DOI: 10.1002/Chem.201300696  0.787
2013 Battilocchio C, Hawkins JM, Ley SV. A mild and efficient flow procedure for the transfer hydrogenation of ketones and aldehydes using hydrous zirconia. Organic Letters. 15: 2278-81. PMID 23590578 DOI: 10.1021/Ol400856G  0.681
2013 Hopkin MD, Baxendale IR, Ley SV. An expeditious synthesis of imatinib and analogues utilising flow chemistry methods. Organic & Biomolecular Chemistry. 11: 1822-39. PMID 23247615 DOI: 10.1039/C2Ob27002A  0.381
2013 Watts CA, Richards FM, Bender A, Bond PJ, Korb O, Kern O, Riddick M, Owen P, Myers RM, Raff J, Gergely F, Jodrell DI, Ley SV. Abstract B96: Design, synthesis and biological evaluation of a novel allosteric inhibitor of HSET that damages cancer cells with supernumerary centrosomes. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B96  0.686
2013 Baxendale IR, Hornung C, Ley SV, De Mata Muñoz Molina J, Wikström A. Flow microwave technology and microreactors in synthesis Australian Journal of Chemistry. 66: 131-144. DOI: 10.1071/Ch12365  0.36
2013 Nakayama K, Browne DL, Baxendale IR, Ley SV. Studies of a diastereoselective electrophilic fluorination reaction employing a cryo-flow reactor Synlett. 24: 1298-1302. DOI: 10.1055/S-0033-1338455  0.636
2013 Fernández A, Levine ZG, Baumann M, Sulzer-Mossé S, Sparr C, Schläger S, Metzger A, Baxendale IR, Ley SV. Synthesis of (-)-hennoxazole A: Integrating batch and flow chemistry methods Synlett. 24: 514-518. DOI: 10.1055/S-0032-1318109  0.463
2013 Kraus H, Français A, O'Brien M, Frost J, Diéguez-Vázquez A, Polara A, Baricordi N, Horan R, Hsu DS, Tsunoda T, Ley SV. Synthesis of spongistatin 2 employing a new route to the EF fragment Chemical Science. 4: 1989-1994. DOI: 10.1039/C3Sc50304F  0.385
2013 Deadman BJ, Battilocchio C, Sliwinski E, Ley SV. A prototype device for evaporation in batch and flow chemical processes Green Chemistry. 15: 2050-2055. DOI: 10.1039/C3Gc40967H  0.772
2013 Guetzoyan L, Nikbin N, Baxendale IR, Ley SV. Flow chemistry synthesis of zolpidem, alpidem and other GABAA agonists and their biological evaluation through the use of in-line frontal affinity chromatography Chemical Science. 4: 764-769. DOI: 10.1039/C2Sc21850J  0.346
2013 Murray PRD, Browne DL, Pastre JC, Butters C, Guthrie D, Ley SV. Continuous flow-processing of organometallic reagents using an advanced peristaltic pumping system and the telescoped flow synthesis of (E/Z)-tamoxifen Organic Process Research and Development. 17: 1192-1208. DOI: 10.1021/Op4001548  0.668
2013 Pastre JC, Browne DL, O'Brien M, Ley SV. Scaling up of continuous flow processes with gases using a tube-in-tube reactor: Inline titrations and fanetizole synthesis with ammonia Organic Process Research and Development. 17: 1183-1191. DOI: 10.1021/Op400152R  0.619
2013 Browne DL, Harji BH, Ley SV. Continuous Cold without Cryogenic Consumables: Development of a Convenient Laboratory Tool for Low-Temperature Flow Processes Chemical Engineering and Technology. 36: 959-967. DOI: 10.1002/Ceat.201200581  0.647
2013 Bourne SL, O'Brien M, Kasinathan S, Koos P, Tolstoy P, Hu DX, Bates RW, Martin B, Schenkel B, Ley SV. Flow Chemistry Syntheses of Styrenes, Unsymmetrical Stilbenes and Branched Aldehydes Chemcatchem. 5: 159-172. DOI: 10.1002/Cctc.201200778  0.681
2013 Bourne SL, Ley SV. A continuous flow solution to achieving efficient aerobic anti-Markovnikov Wacker oxidation Advanced Synthesis and Catalysis. 355: 1905-1910. DOI: 10.1002/Adsc.201300278  0.342
2012 Beale TM, Allwood DM, Bender A, Bond PJ, Brenton JD, Charnock-Jones DS, Ley SV, Myers RM, Shearman JW, Temple J, Unger J, Watts CA, Xian J. A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles. Acs Medicinal Chemistry Letters. 3: 177-81. PMID 24900453 DOI: 10.1021/Ml200149G  0.764
2012 Tran G, Meier R, Harris L, Browne DL, Ley SV. Synthesis and use of a trifluoromethylated azomethine ylide precursor. The Journal of Organic Chemistry. 77: 11071-8. PMID 23176732 DOI: 10.1021/Jo302052M  0.665
2012 Tolstoy P, Lee SX, Sparr C, Ley SV. Synthesis of enantiomerically enriched 3-amino-2-oxindoles through a palladium-mediated asymmetric intramolecular arylation of α-ketimino amides. Organic Letters. 14: 4810-3. PMID 22946713 DOI: 10.1021/Ol302119J  0.424
2012 Frost JR, Pearson CM, Snaddon TN, Booth RA, Ley SV. Convergent total syntheses of callipeltosides A, B, and C. Angewandte Chemie (International Ed. in English). 51: 9366-71. PMID 22915468 DOI: 10.1002/Anie.201204868  0.696
2012 Hu DX, O'Brien M, Ley SV. Continuous multiple liquid-liquid separation: diazotization of amino acids in flow. Organic Letters. 14: 4246-9. PMID 22866828 DOI: 10.1021/Ol301930H  0.313
2012 O'Brien M, Koos P, Browne DL, Ley SV. A prototype continuous-flow liquid-liquid extraction system using open-source technology. Organic & Biomolecular Chemistry. 10: 7031-6. PMID 22858870 DOI: 10.1039/C2Ob25912E  0.6
2012 Browne DL, Wright S, Deadman BJ, Dunnage S, Baxendale IR, Turner RM, Ley SV. Continuous flow reaction monitoring using an on-line miniature mass spectrometer. Rapid Communications in Mass Spectrometry : Rcm. 26: 1999-2010. PMID 22847699 DOI: 10.1002/Rcm.6312  0.64
2012 Ingham RJ, Riva E, Nikbin N, Baxendale IR, Ley SV. A "catch-react-release" method for the flow synthesis of 2-aminopyrimidines and preparation of the Imatinib base. Organic Letters. 14: 3920-3. PMID 22812401 DOI: 10.1021/Ol301673Q  0.348
2012 Ley SV. On being green: can flow chemistry help? Chemical Record (New York, N.Y.). 12: 378-90. PMID 22711555 DOI: 10.1002/Tcr.201100041  0.384
2012 Cranwell PB, O'Brien M, Browne DL, Koos P, Polyzos A, Peña-López M, Ley SV. Flow synthesis using gaseous ammonia in a Teflon AF-2400 tube-in-tube reactor: Paal-Knorr pyrrole formation and gas concentration measurement by inline flow titration. Organic & Biomolecular Chemistry. 10: 5774-9. PMID 22532036 DOI: 10.1039/C2Ob25407G  0.762
2012 Beale TM, Bond PJ, Brenton JD, Charnock-Jones DS, Ley SV, Myers RM. Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A-1. Bioorganic & Medicinal Chemistry. 20: 1749-59. PMID 22304851 DOI: 10.1016/J.Bmc.2012.01.010  0.703
2012 Wegner J, Ley SV, Kirschning A, Hansen AL, Garcia JM, Baxendale IR. A total synthesis of millingtonine A. Organic Letters. 14: 696-9. PMID 22260734 DOI: 10.1021/Ol203158P  0.404
2012 Petersen TP, Polyzos A, O'Brien M, Ulven T, Baxendale IR, Ley SV. The oxygen-mediated synthesis of 1,3-butadiynes in continuous flow: using Teflon AF-2400 to effect gas/liquid contact. Chemsuschem. 5: 274-7. PMID 21948655 DOI: 10.1002/Cssc.201100339  0.657
2012 Koos P, Browne DL, Ley SV. Continuous stream processing: A prototype magnetic field induced flow mixer Green Processing and Synthesis. 1: 11-18. DOI: 10.1515/Greenps-2011-0501  0.602
2012 Ley SV, Newton S. Synthesis of (–)-Clavulactone Synfacts. 8: 937-937. DOI: 10.1055/S-0032-1317042  0.365
2012 Ley SV, Newton S. Synthesis of (–)-Polycavernoside A Synfacts. 8: 941-941. DOI: 10.1055/S-0032-1317041  0.365
2012 Ley SV, Newton S. Synthesis of (–)-Teucvidin Synfacts. 8: 933-933. DOI: 10.1055/S-0032-1317040  0.365
2012 Ley SV, Carter CF. Syntheses of Chelidonine and Norchelidonine Synfacts. 8: 930-930. DOI: 10.1055/S-0032-1317039  0.364
2012 Ley SV, Carter CF. Synthesis of (–)-Aurafuron A Synfacts. 8: 932-932. DOI: 10.1055/S-0032-1317038  0.365
2012 Ley SV, Browne DL. Total Synthesis and Reassignment of 11-Gorgiacerol and 11-Epigorgiacerol Synfacts. 8: 929-929. DOI: 10.1055/S-0032-1317037  0.674
2012 Ley SV, Browne DL. Total Synthesis of (±)−Agelastatin A Synfacts. 8: 946-946. DOI: 10.1055/S-0032-1317036  0.604
2012 Ley SV, Carter CF. Synthesis of (+)-Gelsemine Synfacts. 8: 818-818. DOI: 10.1055/S-0032-1316650  0.402
2012 Ley SV, Frost JR. Synthesis of (–)-Berkelic Acid Synfacts. 8: 813-813. DOI: 10.1055/S-0032-1316649  0.339
2012 Ley SV, Frost JR. Synthesis of (–)-13-Oxyingenol and Its Natural Derivative Synfacts. 8: 816-816. DOI: 10.1055/S-0032-1316648  0.384
2012 Ley SV, Browne DL. Synthesis of (–)-Mersicarpine Synfacts. 8: 827-827. DOI: 10.1055/S-0032-1316647  0.662
2012 Ley SV, Newton S. Synthesis of Pellasoren A Synfacts. 8: 820-820. DOI: 10.1055/S-0032-1316646  0.402
2012 Ley SV, Roper KA. Synthesis of Anominine and Tubingensin A Synfacts. 8: 814-814. DOI: 10.1055/S-0032-1316645  0.402
2012 Ley SV, Roper KA. Synthesis of (+)-Chimonanthine Synfacts. 8: 821-821. DOI: 10.1055/S-0032-1316644  0.402
2012 Ley SV, Roper KA. Synthesis of Hopeanol and Hopeahainol A Synfacts. 8: 699-699. DOI: 10.1055/S-0032-1289844  0.402
2012 Ley SV, Newton S. Synthesis of (+)-Merobatzelladine B Synfacts. 8: 695-695. DOI: 10.1055/S-0032-1289843  0.312
2012 Ley SV, Frost JR. Synthesis of (–)-Goniotrionin Synfacts. 8: 705-705. DOI: 10.1055/S-0032-1289842  0.365
2012 Ley SV, Cranwell PB. Synthesis of (+)-Amabiline Synfacts. 8: 706-706. DOI: 10.1055/S-0032-1289841  0.402
2012 Ley SV, Carter CF. Synthesis of (+)-Scholarisine A Synfacts. 8: 700-700. DOI: 10.1055/S-0032-1289840  0.402
2012 Ley SV, Browne DL. Synthesis of ent-Palmyrolide A Synfacts. 8: 708-708. DOI: 10.1055/S-0032-1289839  0.68
2012 Ley SV, Browne DL. Synthesis of (–)-Hanishin, (–)-Longamide B and (–)-Longamide B Methyl Ester Synfacts. 8: 696-696. DOI: 10.1055/S-0032-1289838  0.611
2012 Ley SV, Cranwell PB. Synthesis of (–)-GB17 Synfacts. 8: 589-589. DOI: 10.1055/S-0031-1291054  0.365
2012 Ley SV, Carter CF. Synthesis of (–)-Anisatin Synfacts. 8: 585-585. DOI: 10.1055/S-0031-1291053  0.365
2012 Ley SV, Roper KA. Synthesis of (–)-Dendrobine Synfacts. 8: 592-592. DOI: 10.1055/S-0031-1291052  0.365
2012 Ley SV, Newton S, Tang W, Prusov EV. Synthesis of Ripostatin B Synfacts. 8: 586-586. DOI: 10.1055/S-0031-1291051  0.312
2012 Ley SV, Browne DL. Synthesis of (S)-Bisoranjidiol Synfacts. 8: 588-588. DOI: 10.1055/S-0031-1291049  0.641
2012 Browne D, O'Brien M, Koos P, Cranwell PB, Polyzos A, Ley SV. Continuous-flow processing of gaseous ammonia using a Teflon AF-2400 tube-in-tube reactor: Synthesis of thioureas and in-line titrations Synlett. 23: 1402-1406. DOI: 10.1055/S-0031-1290963  0.763
2012 Ley SV, Browne DL. Formal Synthesis of Aspergillide B Synfacts. 8: 471-471. DOI: 10.1055/S-0031-1290898  0.629
2012 Ley SV, Browne DL. Enantioselective Synthesis of Pumiliotoxin C and trans-195A Synfacts. 8: 469-469. DOI: 10.1055/S-0031-1290897  0.626
2012 Ley SV, Newton S. Synthesis of (+)-Ambuic Acid Synfacts. 8: 474-474. DOI: 10.1055/S-0031-1290896  0.346
2012 Ley SV, Frost JR. Synthesis of (+)-Cyperolone Synfacts. 8: 479-479. DOI: 10.1055/S-0031-1290895  0.402
2012 Ley SV, Roper KA. Synthesis of the Amathaspiramides Synfacts. 8: 476-476. DOI: 10.1055/S-0031-1290892  0.402
2012 Ley SV, Roper KA. Synthesis of (+)-Lactiflorin Synfacts. 8: 353-353. DOI: 10.1055/S-0031-1290573  0.402
2012 Ley SV, Newton S. Total Synthesis of Carolacton Synfacts. 8: 363-363. DOI: 10.1055/S-0031-1290572  0.392
2012 Ley SV, Newton S. Total Synthesis of (–)-Apicularen A Synfacts. 8: 362-362. DOI: 10.1055/S-0031-1290571  0.362
2012 Ley SV, Carter CF. Synthesis of (–)-Stenine Synfacts. 8: 358-358. DOI: 10.1055/S-0031-1290568  0.365
2012 Ley SV, Cranwell PB. Synthesis of Hyperpapuanone Synfacts. 8: 234-234. DOI: 10.1055/S-0031-1290245  0.402
2012 Ley SV, Roper KA. Synthesis of (–)-Arabilin Synfacts. 8: 242-242. DOI: 10.1055/S-0031-1290244  0.365
2012 Ley SV, Roper KA. Synthesis of (+)-Saxitoxin Synfacts. 8: 235-235. DOI: 10.1055/S-0031-1290243  0.402
2012 Ley SV, Newton S. Synthesis of (+)-Taxadiene Synfacts. 8: 243-243. DOI: 10.1055/S-0031-1290242  0.402
2012 Ley SV, Frost JR. Synthesis of Tulearin C Synfacts. 8: 237-237. DOI: 10.1055/S-0031-1290241  0.35
2012 Ley SV, Frost JR. Synthesis of Brevianamide E Synfacts. 8: 241-241. DOI: 10.1055/S-0031-1290240  0.302
2012 Ley SV, Browne DL. Total Synthesis of (±)-γ-Lycorane Synfacts. 8: 131-131. DOI: 10.1055/S-0031-1290185  0.604
2012 Ley SV, Frost JR. Synthesis of Epoxykinamycin FL-120B′ Synfacts. 8: 128-128. DOI: 10.1055/S-0031-1290183  0.4
2012 Ley SV, Newton S. Synthesis of Cribrostatin 6 Synfacts. 8: 124-124. DOI: 10.1055/S-0031-1290181  0.402
2012 Ley SV, Browne DL. Total Synthesis and Structural Revision of the Piperarborenines Synfacts. 8: 119-119. DOI: 10.1055/S-0031-1290180  0.64
2012 Ley SV, Cranwell PB. Synthesis of (+)-Daphmanidin E Synfacts. 8: 118-118. DOI: 10.1055/S-0031-1290179  0.302
2012 Ley SV, Browne DL. Synthesis of (±)-Hamayne Synfacts. 8: 13-13. DOI: 10.1055/S-0031-1289923  0.601
2012 Ley SV, Cranwell PB. Synthesis of (–)-Huperzine A Synfacts. 8: 7-7. DOI: 10.1055/S-0031-1289922  0.366
2012 Ley SV, Newton S. Synthesis of (+)-Yohimbine Synfacts. 8: 11-11. DOI: 10.1055/S-0031-1289921  0.402
2012 Ley SV, Carter CF. Synthesis of Gelsemoxonine Synfacts. 8: 2-2. DOI: 10.1055/S-0031-1289920  0.402
2012 Ley SV, O’Brien M. Synthesis of Pyripyropene A Synfacts. 8: 3-3. DOI: 10.1055/S-0031-1289919  0.402
2012 Battilocchio C, Baumann M, Baxendale IR, Biava M, Kitching MO, Ley SV, Martin RE, Ohnmacht SA, Tappin NDC. Scale-up of flow-assisted synthesis of C 2-symmetric chiral PyBox ligands Synthesis. 44: 635-647. DOI: 10.1055/S-0031-1289676  0.795
2012 Battilocchio C, Baxendale IR, Biava M, Kitching MO, Ley SV. A flow-based synthesis of 2-aminoadamantane-2-carboxylic acid Organic Process Research and Development. 16: 798-810. DOI: 10.1021/Op300084Z  0.812
2012 Brodmann T, Koos P, Metzger A, Knochel P, Ley SV. Continuous preparation of arylmagnesium reagents in flow with inline IR monitoring Organic Process Research and Development. 16: 1102-1113. DOI: 10.1021/Op200275D  0.385
2012 Hu DX, Bielitza M, Koos P, Ley SV. A total synthesis of the ammonium ionophore, (-)-enniatin B Tetrahedron Letters. 53: 4077-4079. DOI: 10.1016/J.Tetlet.2012.05.110  0.43
2012 Newton S, Ley SV, Arcé EC, Grainger DM. Asymmetric homogeneous hydrogenation in flow using a tube-in-tube reactor Advanced Synthesis and Catalysis. 354: 1805-1812. DOI: 10.1002/Adsc.201200073  0.31
2012 Myers RM, Roper KA, Baxendale IR, Ley SV. The Evolution of Immobilized Reagents and their Application in Flow Chemistry for the Synthesis of Natural Products and Pharmaceutical Compounds Modern Tools For the Synthesis of Complex Bioactive Molecules. 359-393. DOI: 10.1002/9781118342886.ch11  0.729
2011 Roper KA, Lange H, Polyzos A, Berry MB, Baxendale IR, Ley SV. The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors. Beilstein Journal of Organic Chemistry. 7: 1648-55. PMID 22238543 DOI: 10.3762/Bjoc.7.194  0.7
2011 Koos P, Gross U, Polyzos A, O'Brien M, Baxendale I, Ley SV. Teflon AF-2400 mediated gas-liquid contact in continuous flow methoxycarbonylations and in-line FTIR measurement of CO concentration. Organic & Biomolecular Chemistry. 9: 6903-8. PMID 21874192 DOI: 10.1039/C1Ob06017A  0.666
2011 Oelke AJ, France DJ, Hofmann T, Wuitschik G, Ley SV. Piperazic acid-containing natural products: isolation, biological relevance and total synthesis. Natural Product Reports. 28: 1445-71. PMID 21731941 DOI: 10.1039/C1Np00041A  0.316
2011 Browne DL, Baumann M, Harji BH, Baxendale IR, Ley SV. A new enabling technology for convenient laboratory scale continuous flow processing at low temperatures. Organic Letters. 13: 3312-5. PMID 21615126 DOI: 10.1021/Ol2010006  0.646
2011 Lupo G, Gestri G, O'Brien M, Denton RM, Chandraratna RA, Ley SV, Harris WA, Wilson SW. Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme. Proceedings of the National Academy of Sciences of the United States of America. 108: 8698-703. PMID 21555593 DOI: 10.1073/Pnas.1103802108  0.622
2011 Baumann M, Baxendale IR, Kuratli C, Ley SV, Martin RE, Schneider J. Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods. Acs Combinatorial Science. 13: 405-13. PMID 21528880 DOI: 10.1021/Co2000357  0.336
2011 Oelke AJ, Antonietti F, Bertone L, Cranwell PB, France DJ, Goss RJ, Hofmann T, Knauer S, Moss SJ, Skelton PC, Turner RM, Wuitschik G, Ley SV. Total synthesis of chloptosin: a dimeric cyclohexapeptide. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 4183-94. PMID 21412862 DOI: 10.1002/Chem.201003216  0.423
2011 Carter CF, Lange H, Sakai D, Baxendale IR, Ley SV. Diastereoselective chain-elongation reactions using microreactors for applications in complex molecule assembly. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 3398-405. PMID 21344524 DOI: 10.1002/Chem.201003148  0.372
2011 Qi X, Loiseau F, Chan WL, Yan Y, Wei Z, Milroy LG, Myers RM, Ley SV, Read RJ, Carrell RW, Zhou A. Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins. The Journal of Biological Chemistry. 286: 16163-73. PMID 21325280 DOI: 10.1074/Jbc.M110.171082  0.665
2011 Smith CJ, Nikbin N, Ley SV, Lange H, Baxendale IR. A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles. Organic & Biomolecular Chemistry. 9: 1938-47. PMID 21283874 DOI: 10.1039/C0Ob00815J  0.392
2011 Smith CJ, Smith CD, Nikbin N, Ley SV, Baxendale IR. Flow synthesis of organic azides and the multistep synthesis of imines and amines using a new monolithic triphenylphosphine reagent. Organic & Biomolecular Chemistry. 9: 1927-37. PMID 21283873 DOI: 10.1039/C0Ob00813C  0.584
2011 Polyzos A, O'Brien M, Petersen TP, Baxendale IR, Ley SV. The continuous-flow synthesis of carboxylic acids using CO2 in a tube-in-tube gas permeable membrane reactor. Angewandte Chemie (International Ed. in English). 50: 1190-3. PMID 21268224 DOI: 10.1002/Anie.201006618  0.661
2011 Français A, Leyva-Pérez A, Etxebarria-Jardi G, Peña J, Ley SV. Total synthesis of iso- and bongkrekic acids: natural antibiotics displaying potent antiapoptotic properties. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 329-43. PMID 21207629 DOI: 10.1002/Chem.201002380  0.41
2011 Martin LJ, Marzinzik AL, Ley SV, Baxendale IR. Safe and reliable synthesis of diazoketones and quinoxalines in a continuous flow reactor. Organic Letters. 13: 320-3. PMID 21162548 DOI: 10.1021/Ol1027927  0.369
2011 Baumann M, Baxendale IR, Ley SV. The flow synthesis of heterocycles for natural product and medicinal chemistry applications. Molecular Diversity. 15: 613-30. PMID 20960230 DOI: 10.1007/S11030-010-9282-1  0.37
2011 Shearman JW, Myers RM, Brenton JD, Ley SV. Total syntheses of subereamollines A and B. Organic & Biomolecular Chemistry. 9: 62-5. PMID 20953439 DOI: 10.1039/C0Ob00636J  0.719
2011 Kasinathan S, Bourne SL, Tolstoy P, Koos P, Obrien M, Bates RW, Baxendale IR, Ley SV. Syngas-mediated C-C bond formation in flow: Selective rhodium-catalysed hydroformylation of styrenes Synlett. 2648-2651. DOI: 10.1055/S-0031-1289292  0.632
2011 Bourne SL, Koos P, Obrien M, Martin B, Schenkel B, Baxendale IR, Ley SV. The continuous-flow synthesis of styrenes using ethylene in a palladium-catalysed heck cross-coupling reaction Synlett. 2643-2647. DOI: 10.1055/S-0031-1289291  0.397
2011 Lange H, Capener MJ, Jones AX, Smith CJ, Nikbin N, Baxendale IR, Ley SV. Flow Oxidation Reactions Using Polystyrene-Supported Reagents Synfacts. 2011: 794-794. DOI: 10.1055/S-0030-1260593  0.314
2011 Baumann M, Baxendale IR, Brasholz M, Hayward JJ, Ley SV, Nikbin N. An integrated flow and batch-based approach for the synthesis of O -methyl siphonazole Synlett. 1375-1380. DOI: 10.1055/S-0030-1260573  0.333
2011 O'Brien M, Denton R, Ley SV. Lesser-known enabling technologies for organic synthesis Synthesis. 1157-1192. DOI: 10.1055/S-0030-1259979  0.666
2011 Lange H, Capener MJ, Jones AX, Smith CJ, Nikbin N, Baxendale IR, Ley SV. Oxidation reactions in segmented and continuous flow chemical processing using an N -(tert -Butyl)phenylsulfinimidoyl chloride monolith Synlett. 869-873. DOI: 10.1055/S-0030-1259923  0.365
2011 O'Brien M, Taylor N, Polyzos A, Baxendale IR, Ley SV. Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas-liquid contact at elevated pressure Chemical Science. 2: 1250-1257. DOI: 10.1039/C1Sc00055A  0.661
2011 Lange H, Carter CF, Hopkin MD, Burke A, Goode JG, Baxendalea IR, Ley SV. A breakthrough method for the accurate addition of reagents in multi-step segmented flow processing Chemical Science. 2: 765-769. DOI: 10.1039/C0Sc00603C  0.347
2011 Browne DL, Deadman BJ, Ashe R, Baxendale IR, Ley SV. Continuous flow processing of slurries: Evaluation of an agitated cell reactor Organic Process Research and Development. 15: 693-697. DOI: 10.1021/Op2000223  0.633
2011 Browne DL, Baxendale IR, Ley SV. Piecing together the puzzle: Understanding a mild, metal free reduction method for the large scale synthesis of hydrazines Tetrahedron. 67: 10296-10303. DOI: 10.1016/J.Tet.2011.09.146  0.643
2010 Kolstoe SE, Mangione PP, Bellotti V, Taylor GW, Tennent GA, Deroo S, Morrison AJ, Cobb AJ, Coyne A, McCammon MG, Warner TD, Mitchell J, Gill R, Smith MD, Ley SV, et al. Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proceedings of the National Academy of Sciences of the United States of America. 107: 20483-8. PMID 21059958 DOI: 10.1073/Pnas.1008255107  0.687
2010 Malet-Sanz L, Madrzak J, Ley SV, Baxendale IR. Preparation of arylsulfonyl chlorides by chlorosulfonylation of in situ generated diazonium salts using a continuous flow reactor. Organic & Biomolecular Chemistry. 8: 5324-32. PMID 20877783 DOI: 10.1039/C0Ob00450B  0.377
2010 Qian Z, Baxendale IR, Ley SV. A continuous flow process using a sequence of microreactors with in-line IR analysis for the preparation of N,N-diethyl-4-(3-fluorophenylpiperidin-4-ylidenemethyl)benzamide as a potent and highly selective δ-opioid receptor agonist. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 12342-8. PMID 20859972 DOI: 10.1002/Chem.201002147  0.31
2010 Sedelmeier J, Ley SV, Baxendale IR, Baumann M. KMnO(4)-Mediated oxidation as a continuous flow process. Organic Letters. 12: 3618-21. PMID 20704404 DOI: 10.1021/Ol101345Z  0.334
2010 Oelke AJ, France DJ, Hofmann T, Wuitschik G, Ley SV. Total synthesis of chloptosin. Angewandte Chemie (International Ed. in English). 49: 6139-42. PMID 20645377 DOI: 10.1055/S-0030-1258880  0.401
2010 Venturoni F, Nikbin N, Ley SV, Baxendale IR. The application of flow microreactors to the preparation of a family of casein kinase I inhibitors. Organic & Biomolecular Chemistry. 8: 1798-806. PMID 20449482 DOI: 10.1039/B925327K  0.339
2010 Hopkin MD, Baxendale IR, Ley SV. A flow-based synthesis of imatinib: the API of Gleevec. Chemical Communications (Cambridge, England). 46: 2450-2. PMID 20309467 DOI: 10.1039/C001550D  0.383
2010 Carter CF, Baxendale IR, Pavey JB, Ley SV. The continuous flow synthesis of butane-2,3-diacetal protected building blocks using microreactors. Organic & Biomolecular Chemistry. 8: 1588-95. PMID 20237669 DOI: 10.1039/B924309G  0.394
2010 Francais A, Leyva A, Etxebarria-Jardi G, Ley SV. Total synthesis of the anti-apoptotic agents iso- and bongkrekic acids. Organic Letters. 12: 340-3. PMID 20014782 DOI: 10.1021/Ol902676T  0.38
2010 Baxendale IR, Schou SC, Sedelmeier J, Ley SV. Multi-step synthesis by using modular flow reactors: the preparation of yne--ones and their use in heterocycle synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 89-94. PMID 19938024 DOI: 10.1002/Chem.200902906  0.434
2010 Baumann M, Baxendale IR, Kirschning A, Ley SV, Wegner J. Synthesis of highly substituted nitropyrrolidines, nitropyrrolizines and nitropyrroles via multicomponent-multistep sequences within a flow reactor Heterocycles. 82: 1297-1316. DOI: 10.3987/Com-10-S(E)77  0.364
2010 Tozzi F, Ley SV, Kitching MO, Baxendale IR. Enzymatic oxidative cyclisation reactions leading to dibenzoazocanes Synlett. 1919-1922. DOI: 10.1055/S-0030-1258486  0.671
2010 Francais A, Leyva A, Etxebarria-Jardi G, Ley SV. Synthesis of Iso- and Bongkrekic Acids Synfacts. 2010: 509-509. DOI: 10.1055/S-0029-1219712  0.346
2010 Baxendale IR, Schou SC, Sedelmeier J, Ley SV. General Syntheses of Heterocycles Using Modular Flow Reactors Synfacts. 2010: 279-279. DOI: 10.1055/S-0029-1219431  0.328
2010 Qian Z, Baxendale IR, Ley SV. A flow process using microreactors for the preparation of a quinolone derivative as a potent 5HT1B antagonist Synlett. 505-508. DOI: 10.1055/S-0029-1219358  0.342
2010 Baumann M, Baxendale IR, Ley SV. Synthesis of 3-nitropyrrolidines via dipolar cycloaddition reactions using a modular flow reactor Synlett. 749-752. DOI: 10.1055/S-0029-1219344  0.395
2010 Beale TM, Myers RM, Shearman JW, Charnock-Jones DS, Brenton JD, Gergely FV, Ley SV. Antivascular and anticancer activity of dihalogenated A-ring analogues of combretastatin A-4 Medchemcomm. 1: 202-208. DOI: 10.1039/C0Md00095G  0.695
2010 Yasuda K, Ley SV. The Simultaneous Use of Immobilized Reagents for the One-Pot Conversion of Alcohols to Carboxylic Acids. Cheminform. 33: 48-48. DOI: 10.1039/B201776H  0.318
2010 Carter CF, Lange H, Ley SV, Baxendale IR, Wittkamp B, Goode JG, Gaunt NL. ReactIR flow cell: A new analytical tool for continuous flow chemical processing Organic Process Research and Development. 14: 393-404. DOI: 10.1021/Op900305V  0.322
2010 Shearman JW, Myers RM, Beale TM, Brenton JD, Ley SV. Total syntheses of the bromotyrosine-derived natural products ianthelline, 5-bromoverongamine and JBIR-44 Tetrahedron Letters. 51: 4812-4814. DOI: 10.1016/J.Tetlet.2010.07.016  0.705
2010 Bezuidenhoudt BCB, Castle GH, Innes JE, Ley SV. Dispiroketals in synthesis (Part 16): Functionalised dispiroketals as new chiral auxiliaries; the synthesis of dihydroxylated dispiroketals in optically pure form and their application as bifunctional, C2-symmetrical, chiral auxiliaries for highly stereos Recueil Des Travaux Chimiques Des Pays-Bas. 114: 184-194. DOI: 10.1002/Recl.19951140410  0.387
2010 Catalán-Muñoz S, Müller CA, Ley SV. An asymmetric tandem conjugative addition-intramolecular cyclisation process to provide functionalised 3,6-dihydropyrans and 4,5- epoxytetrahydropyrans European Journal of Organic Chemistry. 183-190. DOI: 10.1002/Ejoc.200901145  0.434
2010 Dixon DJ, Forster AC, Ley SV. ChemInform Abstract: The Total Synthesis of (+)-Aspicilin Using 2,3-Butane Diacetal Protected Butane Tetrols via a Chiral Memory Protocol. Cheminform. 33: no-no. DOI: 10.1002/chin.200226207  0.484
2010 Dixon DJ, Ley SV, Rodriguez F. ChemInform Abstract: Consecutive Three- and Four-Component Coupling Reactions with Anions Generated from a Butane Diacetal Desymmetrized Glycolic Acid Derivative. Cheminform. 33: no-no. DOI: 10.1002/chin.200219039  0.525
2010 Dixon DJ, Ley SV, Polara A, Sheppard T. ChemInform Abstract: Highly Diastereoselective Lithium Enolate Aldol Reactions of Butane-2,3-diacetal Desymmetrized Glycolic Acid and Deprotection to Enantiopure anti-2,3-Dihydroxy Esters. Cheminform. 33: no-no. DOI: 10.1002/chin.200217143  0.698
2010 Dixon DJ, Ley SV, Rodriguez F. ChemInform Abstract: Highly Diastereoselective Michael Addition Reactions of Butane-2,3-diacetal Desymmetrized Glycolic Acid. Preparation of α-Hydroxy-γ-amino Acid Derivatives. Cheminform. 33: no-no. DOI: 10.1002/chin.200216062  0.516
2010 Dixon DJ, Ley SV, Reynolds DJ, Chorghade MS. ChemInform Abstract: A Short and Efficient Stereoselective Synthesis of the Potent 5-Lipoxygenase Inhibitor CMI-977. Cheminform. 31: no-no. DOI: 10.1002/chin.200035093  0.527
2010 Ley SV, Burckhardt S, Cox LR, Worrall JM. ChemInform Abstract: Reductive Decomplexation of π-Allyltricarbonyliron Lactone Complexes: A New Route to Stereodefined Acyclic 1,5-Diols and 1,5,7-Triols. Cheminform. 31: no-no. DOI: 10.1002/chin.200019054  0.594
2010 Dixon DJ, Foster AC, Ley SV. ChemInform Abstract: A Short and Efficient Stereoselective Synthesis of the Polyhydroxylated Macrolactone (+)-Aspicilin. Cheminform. 31: no-no. DOI: 10.1002/chin.200015203  0.55
2010 Dixon DJ, Ley SV, Tate EW. ChemInform Abstract: Highly cis- or trans-Selective Oxygen to Carbon Rearrangements of Anomerically Linked 6-Substituted Tetrahydropyranyl Enol Ethers. Cheminform. 31: no-no. DOI: 10.1002/chin.200004150  0.633
2010 Bates RW, Fernandez-Megia E, Ley SV, Rueck-Braun K, Tilbrook DMG. ChemInform Abstract: Total Synthesis of the Cholesterol Biosynthesis Inhibitor 1233A via a (π-Allyl)tricarbonyliron Lactone Complex. Cheminform. 30: no-no. DOI: 10.1002/chin.199945284  0.575
2010 Dixon DJ, Foster AC, Ley SV, Reynolds DJ. ChemInform Abstract: A General and Efficient Procedure for the Preparation of Enantiopure anti-1,2-Diols. Synthesis and Utility of (R′,R′,S,R)-2,3-Butane Diacetal Protected Butane Tetrol. Cheminform. 30: no-no. DOI: 10.1002/chin.199945043  0.507
2010 Dixon DJ, Ley SV, Longbottom DA. ChemInform Abstract: Total Synthesis of the Plasmoidal Pigment Physarorubinic Acid, a Polyenoyl Tetramic Acid. Cheminform. 30: no-no. DOI: 10.1002/chin.199944189  0.494
2010 Barlow JS, Dixon DJ, Foster AC, Ley SV, Reynolds DJ. ChemInform Abstract: New Building Blocks for Efficient and Highly Diastereoselective Polyol Production. Synthesis and Utility of (R′,R′,S,S) and (S′,S′,R,R)-2,3-Butane Diacetal Protected Butane Tetrol Derivatives. Cheminform. 30: no-no. DOI: 10.1002/chin.199944157  0.488
2010 Dixon DJ, Foster AC, Ley SV, Reynolds DJ. ChemInform Abstract: Preparation of Desymmetrized meso-Tartrate Derivatives. Synthesis and Utility of (R′,R′,R,S)-2,3-Butane Diacetal Protected Dimethyl Tartrate. Cheminform. 30: no-no. DOI: 10.1002/chin.199944040  0.511
2010 Dixon DJ, Ley SV, Gracza T, Szolcsanyi P. ChemInform Abstract: Total Synthesis of the Polyenoyltetramic Acid Mycotoxin Erythroskyrine. Cheminform. 30: no-no. DOI: 10.1002/chin.199932255  0.531
2010 Ley SV, Cox LR, Middleton B, Worrall JM. ChemInform Abstract: 1,7-Induction of Chirality in Mukaiyama Aldol Reactions Using π-Allyltricarbonyliron Lactone and Lactam Complexes as Chiral Templates Cheminform. 30: no-no. DOI: 10.1002/chin.199931028  0.63
2010 DIXON DJ, LEY SV, TATE EW. ChemInform Abstract: A Total Synthesis of (+)-Goniodiol Using an Anomeric Oxygen-to-Carbon Rearrangement. Cheminform. 30: no-no. DOI: 10.1002/chin.199911276  0.643
2010 LEY SV, COX LR, WORRALL JM. ChemInform Abstract: Double Diastereodifferentiation in the Mukaiyama Aldol Reactions of π-Allyltricarbonyliron Lactone Complexes: 1,7- vs. 1,2-Asymmetric Induction. Cheminform. 30: no-no. DOI: 10.1002/chin.199908039  0.62
2010 DIXON DJ, LEY SV, TATE EW. ChemInform Abstract: Diastereoselective Anomeric Oxygen to Carbon Rearrangements of Silyl Enol Ether Derivatives of Lactols. Cheminform. 30: no-no. DOI: 10.1002/chin.199904137  0.634
2010 BUFFET MF, DIXON DJ, LEY SV, TATE EW. ChemInform Abstract: Anomeric Oxygen to Carbon Rearrangements of Alkynyl Tributylstannane Derivatives of Lactols. Cheminform. 30: no-no. DOI: 10.1002/chin.199904136  0.615
2010 COX LR, LEY SV. ChemInform Abstract: Tricarbonyliron Complexes: An Approach to Acyclic Stereocontrol Cheminform. 30: no-no. DOI: 10.1002/chin.199902297  0.552
2010 LEY SV, BROWN DS, CLASE JA, FAIRBANKS AJ, LENNON IC, OSBORN HMI, STOKES ESE, WADSWORTH DJ. ChemInform Abstract: Synthesis of the Acyltetronic Acid Ionophore Tetronasin (ICI M139603). Cheminform. 29: no-no. DOI: 10.1002/chin.199852291  0.531
2010 LEY SV, COX LR, MIDDLETON B, WORRALL JM. ChemInform Abstract: Mukaiyama Aldol Reactions of π-Allyltricarbonyliron Lactone and Lactam Complexes Bearing Trimethylsilyl Enol Ether Side-Chains. Not Just Formal, but Genuine 1,7-Induction of Chirality. Cheminform. 29: no-no. DOI: 10.1002/chin.199845184  0.632
2010 LEY SV, COX LR. ChemInform Abstract: Highly Diastereoselective Synthesis of β-Hydroxy Carbonyl Compounds Using π-Allyltricarbonyliron Lactone Complexes: A Formal 1,7-Asymmetric Induction of Chirality in a Mukaiyama Aldol Reaction. Cheminform. 29: no-no. DOI: 10.1002/chin.199820053  0.654
2010 LEY SV, BURCKHARDT S, COX LR, WORRALL JM. ChemInform Abstract: A Novel Decomplexation of π-Allyltricarbonyliron Lactone Complexes Using Borohydride Reagents: A New Route to Stereodefined Acyclic 1,5-Diols and 1,5,7-Triols. Cheminform. 29: no-no. DOI: 10.1002/chin.199819034  0.608
2010 LEY SV, COX LR. ChemInform Abstract: 1,5-Asymmetric Induction of Chirality: Highly Diastereoselective Synthesis of Homoallylic Tertiary Alcohols by the Lewis Acid-Mediated Addition of Allylstannanes into Ketones in the Side-Chain of π-Allyltricarbonyliron Lactone Complex Cheminform. 29: no-no. DOI: 10.1002/chin.199814038  0.627
2010 LEY SV, COX LR, MEEK G, METTEN K, PIQUE C, WORRALL JM. ChemInform Abstract: 1,5-Asymmetric Induction of Chirality: Highly Diastereoselective Addition Reactions of Organoaluminum Reagents into Ketone Groups in the Side-Chain of π-Allyltricarbonyliron Lactone Complexes. Cheminform. 29: no-no. DOI: 10.1002/chin.199814037  0.633
2010 LEY SV, BURCKHARDT S, COX LR, MEEK G. ChemInform Abstract: 1,5-Asymmetric Induction of Chirality: Diastereoselective Addition of Organoaluminum Reagents and Allylstannanes into Aldehyde Groups in the Side-Chain of π-Allyltricarbonyliron Lactone Complexes. Cheminform. 29: no-no. DOI: 10.1002/chin.199813040  0.608
2010 BUFFET MF, DIXON DJ, EDWARDS GL, LEY SV, TATE E. ChemInform Abstract: A General C-Glycosidation Procedure via Anomeric Oxygen to Carbon Rearrangements of Tetrahydropyranyl Ether Derivatives. Cheminform. 29: no-no. DOI: 10.1002/chin.199803144  0.632
2010 DE LA PUENTE ML, GROSSMAN RB, LEY SV, SIMMONDS MSJ, BLANEY WM. ChemInform Abstract: Chemistry of Insect Antifeedants from Azadirachta indica. Part 20. Synthesis of Biologically Active, Simple Analogues of Azadirachtin, Containing the Hydroxytetrahydrofurancarboxylate Hemiketal Moiety. Cheminform. 27: no-no. DOI: 10.1002/chin.199640104  0.595
2010 LEY SV, COX LR. ChemInform Abstract: Diastereoselective Addition Reactions of Allylstannanes to Carbonyl Groups in the Side-Chain of π-Allyltricarbonyliron Lactone Complexes. Cheminform. 27: no-no. DOI: 10.1002/chin.199629033  0.605
2010 LEY SV, COX LR, MEEK G. ChemInform Abstract: (π-Allyl)tricarbonyliron Lactone Complexes in Organic Synthesis: A Useful and Conceptually Unusual Route to Lactones and Lactams Cheminform. 27: no-no. DOI: 10.1002/chin.199622294  0.632
2010 GENICOT C, LEY SV. ChemInform Abstract: Dispiroketals in Synthesis. Part 15. Simultaneous Enantioselective and Regioselective Protection of Glycerol by Reaction with C2 Symmetric ( 4S,4′S)-Dimethyl-bis-dihydropyran. Cheminform. 26: no-no. DOI: 10.1002/chin.199515060  0.317
2010 GROSSMAN RB, LEY SV. ChemInform Abstract: Chemistry of Insect Antifeedants from Azadirachta indica. Part 17. Synthesis of Model Compounds of Azadirachtin. Unusual Effect of Remote Substituents on the Course of the Oxidative Ring Contraction Reaction. Cheminform. 26: no-no. DOI: 10.1002/chin.199511231  0.584
2010 BEZUIDENHOUDT BCB, CASTLE GH, GEDEN JV, LEY SV. ChemInform Abstract: Dispiroketals in Synthesis. Part 13. Functionalized Dispiroketals as New Chiral Auxiliaries: Highly Stereoselective Diels-Alder Reactions Using a Bifunctional, C2-Symmetrical Chiral Auxiliary. Cheminform. 26: no-no. DOI: 10.1002/chin.199510179  0.306
2010 EDWARDS PJ, ENTWISTLE DA, GENICOT C, KIM KS, LEY SV. ChemInform Abstract: Dispiroketals in Synthesis. Part 11. Concomitant Enantioselective and Regioselective Protection of 2,5-Dibenzoyl-myo-inositol. Cheminform. 26: no-no. DOI: 10.1002/chin.199510177  0.312
2010 LEY SV. ChemInform Abstract: Synthesis and Chemistry of the Insect Antifeedant Azadirachtin. Cheminform. 26: no-no. DOI: 10.1002/chin.199507301  0.315
2010 BOONS G, DOWNHAM R, KIM KS, LEY SV, WOODS M. ChemInform Abstract: Dispiroketals in Synthesis. Part 10. Further Reactions of Dispoke Protected Lactate and Glycolate Enolates. Cheminform. 25: no-no. DOI: 10.1002/chin.199446078  0.542
2010 ANDERSON JC, LEY SV, MARSDEN SP. ChemInform Abstract: Studies Towards the Total Synthesis of Rapamycin: A Convergent and Stereoselective Synthesis of the C22-C32 Carbon Framework Cheminform. 25: no-no. DOI: 10.1002/chin.199429291  0.604
2010 TURNER RM, LEY SV, LINDELL SD. ChemInform Abstract: Synthesis of 4-Substituted Imidazoles via 4-Metalloimidazole Intermediates. Cheminform. 25: no-no. DOI: 10.1002/chin.199425125  0.33
2010 DOWNHAM R, KIM KS, LEY SV, WOODS M. ChemInform Abstract: Dispiroketals in Synthesis. Part 6. Highly Stereoselective Alkylation of Dispiroketal-Protected Lactate (III) and Glycolate Enolates (XIII). Cheminform. 25: no-no. DOI: 10.1002/chin.199424057  0.308
2010 BOONS G, LENNON IC, LEY SV, OWEN ESE, STAUNTON J, WADSWORTH DJ. ChemInform Abstract: Novel Polyene Cyclization Routes to the Acyl Tetronic Acid Ionophore Tetronasin (ICI M139603). Cheminform. 25: no-no. DOI: 10.1002/chin.199418242  0.453
2010 BOONS G, BROWN DS, CLASE JA, LENNON IC, LEY SV. ChemInform Abstract: Two New Routes to the C19-C26 Tetrahydrofuran Fragment (VI) of the Acyl Tetronic Acid Ionophore Tetronasin (ICI M139603). Cheminform. 25: no-no. DOI: 10.1002/chin.199418241  0.438
2010 BOONS G, GRICE P, LESLIE R, LEY SV, YEUNG LL. ChemInform Abstract: Dispiroketals in Synthesis. Part 5. A New Opportunity for Oligosaccharide Synthesis Using Differentially Activated Glycosyl Donors and Acceptors. Cheminform. 25: no-no. DOI: 10.1002/chin.199416246  0.509
2010 LEY SV, BOONS G, LESLIE R, WOODS M, HOLLINSHEAD DM. ChemInform Abstract: Dispiroketals in Synthesis. Part 3. Selective Protection of Diequatorial Vicinal Diols in Carbohydrates. Cheminform. 25: no-no. DOI: 10.1002/chin.199415106  0.504
2010 BOONS G, ENTWISTLE DA, LEY SV, WOODS M. ChemInform Abstract: Dispiroketals in Synthesis. Part 4. Enantioselective Desymmetrization of Glycerol Using a C2-Symmetric Disubstituted Bisdihydropyran. Cheminform. 25: no-no. DOI: 10.1002/chin.199401049  0.519
2010 KOLB HC, LEY SV, SHEPPARD RN, SLAWIN AMZ, SMITH SC, WILLIAMS DJ, WOOD A. ChemInform Abstract: Chemistry of Insect Antifeedants from Azadirachta indica. Part 13. On the Use of the Intramolecular Diels-Alder Reaction for the Construction of trans-Fused Hydrobenzofuran Fragments for Azadirachtin Synthesis. Cheminform. 24: no-no. DOI: 10.1002/chin.199310283  0.627
2010 KOLB HC, LEY SV, SLAWIN AMZ, WILLIAMS DJ. ChemInform Abstract: Chemistry of Insect Antifeedants from Azadirachta indica. Part 12. Use of Silicon as a Control Element in the Synthesis of a Highly Functionalized Decalin Fragment of Azadirachtin. Cheminform. 24: no-no. DOI: 10.1002/chin.199310282  0.56
2010 DIEZ-MARTIN D, KOTECHA NR, LEY SV, MANTEGANI S, MENENDEZ JC, ORGAN HM, WHITE AD, BANKS BJ. ChemInform Abstract: Total Synthesis of the Ionophore Antibiotic CP-61,405 (Routiennocin). Cheminform. 24: no-no. DOI: 10.1002/chin.199301276  0.521
2010 LEY SV, ARMSTRONG A. ChemInform Abstract: The Champagne Route to Avermectins and Milbemycins Cheminform. 23: no-no. DOI: 10.1002/chin.199230271  0.451
2010 LEY SV, WOODS M, ZANOTTI-GEROSA A. ChemInform Abstract: Dispiroketals in Synthesis: Preparation of a Stable, Sterically Demanding Glyceraldehyde Ketal and Diastereoselective Reactions with Simple Organometallic Reagents. Cheminform. 23: no-no. DOI: 10.1002/chin.199230165  0.343
2010 BATES RW, FERNANDEZ-MORO R, LEY SV. ChemInform Abstract: The Use of π-Allyltricarbonyliron Lactone Complexes in the Synthesis of the β-Lactone Esterase Inhibitor (-)-Valilactone. Cheminform. 23: no-no. DOI: 10.1002/chin.199211277  0.58
2010 LEY SV, ANDERSON JC, BLANEY WM, MORGAN ED, SHEPPARD RN, SIMMONDS MSJ, SLAWIN AMZ, SMITH SC, WILLIAMS DJ, WOOD A. ChemInform Abstract: Chemistry of Insect Antifeedants from Azadirachta indica. Part 11. Characterization and Structure Activity Relationships of Some Novel Rearranged Azadirachtins. Cheminform. 23: no-no. DOI: 10.1002/chin.199209306  0.55
2010 LEY SV, TRUDELL ML, WADSWORTH DJ. ChemInform Abstract: Total Synthesis of Agglomerin A and (.+-.)-Carolinic Acid. A General Method for the Preparation of 3-Acyl Tetronic Acids via Direct Acylation of O-Methyl 3-Stannyl Tetronates. Cheminform. 23: no-no. DOI: 10.1002/chin.199204288  0.559
2010 CHARREAU P, LEY SV, VETTIGER TM, VILE S. ChemInform Abstract: Use of Phenylsulfonylmethano Ethers in Synthesis: A New Versatile Route to Substituted Cyclic Ethers. Cheminform. 23: no-no. DOI: 10.1002/chin.199204223  0.32
2010 ANDERSON JC, LEY SV, SANTAFIANOS D, SHEPPARD RN. ChemInform Abstract: Chemistry of Insect Antifeedants from Azadirachta indica. Part 8. Synthesis of Hydroxydihydrofuran Acetal Fragments for Biological Evaluation and Azadirachtin Total Synthesis Studies. Cheminform. 22: no-no. DOI: 10.1002/chin.199148224  0.634
2010 LEY SV, ARMSTRONG A, DIEZ-MARTIN D, FORD MJ, GRICE P, KNIGHT JG, KOLB HC, MADIN A, MARBY CA, MUKHERJEE S, SHAW AN, SLAWIN AMZ, VILE S, WHITE AD, WILLIAMS DJ, et al. ChemInform Abstract: Total Synthesis of the Anthelmintic Macrolide Avermectin B1a. Cheminform. 22: no-no. DOI: 10.1002/chin.199128240  0.614
2010 BROWN DS, CHARREAU P, HANSSON T, LEY SV. ChemInform Abstract: Substitution Reactions of 2-Phenylsulfonyl-piperidines and - pyrrolidines with Carbon Nucleophiles: Synthesis of the Pyrrolidine Alkaloids Norruspoline and Ruspolinone. Cheminform. 22: no-no. DOI: 10.1002/chin.199123066  0.306
2010 ANDERSON JC, LEY SV. ChemInform Abstract: Chemistry of Insect Antifeedants from Azadirachta indica. Part 7. Preparation of an Optically Pure Hydroxyacetal Epoxide (II) Related to Azadirachtin. Cheminform. 22: no-no. DOI: 10.1002/chin.199118295  0.534
2010 Ley SV. New Routes to Biologically Active Heterocyclic Natural Products Bulletin Des SociéTéS Chimiques Belges. 101: 641-642. DOI: 10.1002/Bscb.19921010711  0.306
2009 Carter CF, Baxendale IR, O'Brien M, Pavey JB, Ley SV. Synthesis of acetal protected building blocks using flow chemistry with flow I.R. analysis: preparation of butane-2,3-diacetal tartrates. Organic & Biomolecular Chemistry. 7: 4594-7. PMID 19865693 DOI: 10.1039/B917289K  0.345
2009 Baxendale IR, Ley SV, Piutti C. Total synthesis of the amaryllidaceae alkaloid (+)-plicamine and its unnatural enantiomer by using solid-supported reagents and scavengers in a multistep sequence of reactions. Angewandte Chemie (International Ed. in English). 41: 2194-7. PMID 19746642 DOI: 10.1002/1521-3773(20020617)41:12<2194::Aid-Anie2194>3.0.Co;2-4  0.39
2009 Palmieri A, Ley SV, Polyzos A, Ladlow M, Baxendale IR. Continuous flow based catch and release protocol for the synthesis of alpha-ketoesters. Beilstein Journal of Organic Chemistry. 5: 23. PMID 19590738 DOI: 10.3762/Bjoc.5.23  0.677
2009 Myers RM, Shearman JW, Kitching MO, Ramos-Montoya A, Neal DE, Ley SV. Cancer, chemistry, and the cell: molecules that interact with the neurotensin receptors. Acs Chemical Biology. 4: 503-25. PMID 19462983 DOI: 10.1021/Cb900038E  0.761
2009 Baxendale IR, Ley SV, Mansfield AC, Smith CD. Multistep synthesis using modular flow reactors: Bestmann-Ohira reagent for the formation of alkynes and triazoles. Angewandte Chemie (International Ed. in English). 48: 4017-21. PMID 19388020 DOI: 10.1002/Anie.200900970  0.556
2009 Ley SV, Tackett MN, Maddess ML, Anderson JC, Brennan PE, Cappi MW, Heer JP, Helgen C, Kori M, Kouklovsky C, Marsden SP, Norman J, Osborn DP, Palomero MA, Pavey JB, et al. Total synthesis of rapamycin. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 2874-914. PMID 19204960 DOI: 10.1002/Chem.200801656  0.782
2009 Evans AC, Longbottom DA, Matsuoka M, Davies JE, Turner R, Franckevicius V, Ley SV. Highly diastereoselective desymmetrisation of cyclic meso-anhydrides and derivatisation for use in natural product synthesis. Organic & Biomolecular Chemistry. 7: 747-60. PMID 19194591 DOI: 10.1039/B813494D  0.412
2009 Boyer A, Veitch GE, Beckmann E, Ley SV. Second-generation synthesis of azadirachtin: a concise preparation of the propargylic mesylate fragment. Angewandte Chemie (International Ed. in English). 48: 1317-20. PMID 19140148 DOI: 10.1002/Anie.200805395  0.797
2009 Enríquez-García A, Ley SV. Total synthesis of the potent antifungal agents bengazole C and E Collection of Czechoslovak Chemical Communications. 74: 887-900. DOI: 10.1135/Cccc2009016  0.402
2009 Webb D, Van Den Heuvel A, Kögl M, Ley SV. Enantioselective synthesis of the lyngbouilloside macrolactone core Synlett. 2320-2324. DOI: 10.1055/S-0029-1217707  0.379
2009 Baxendale IR, Buckle CD, Ley SV, Tamborini L. A base-catalysed one-pot three-component coupling reaction leading to nitrosubstituted pyrroles Synthesis. 1485-1493. DOI: 10.1055/S-0028-1087991  0.382
2009 Sedelmeier J, Ley SV, Baxendale IR. An efficient and transition metal free protocol for the transfer hydrogenation of ketones as a continuous flow process Green Chemistry. 11: 683-685. DOI: 10.1039/B821752A  0.321
2009 Palmieri A, Ley SV, Hammond K, Polyzos A, Baxendale IR. A microfluidic flow chemistry platform for organic synthesis: the Hofmann rearrangement Tetrahedron Letters. 50: 3287-3289. DOI: 10.1016/J.Tetlet.2009.02.059  0.71
2009 Baumann M, Baxendale IR, Martin LJ, Ley SV. Development of fluorination methods using continuous-flow microreactors Tetrahedron. 65: 6611-6625. DOI: 10.1016/J.Tet.2009.05.083  0.335
2009 Sedelmeier J, Ley SV, Lange H, Baxendale IR. Pd-EnCat™ TPP30 as a catalyst for the generation of highly functionalized aryl- and alkenyl-substituted acetylenes via microwave-assisted sonogashira type reactions European Journal of Organic Chemistry. 4412-4420. DOI: 10.1002/Ejoc.200900344  0.354
2009 Diéguez-Vázquez A, Tzschucke CC, Creeente-Campo J, McGrath S, Ley SV. AuCl3-catalyzed hydroalkoxylatlon of conjugated alkynoates: Synthesis of five- and six-membered cyclic acetals European Journal of Organic Chemistry. 1698-1706. DOI: 10.1002/Ejoc.200801221  0.728
2008 Veitch GE, Boyer A, Ley SV. The azadirachtin story. Angewandte Chemie (International Ed. in English). 47: 9402-29. PMID 19031481 DOI: 10.1002/Anie.200802675  0.759
2008 Ley SV, Abad-Somovilla A, Anderson JC, Ayats C, Bänteli R, Beckmann E, Boyer A, Brasca MG, Brice A, Broughton HB, Burke BJ, Cleator E, Craig D, Denholm AA, Denton RM, et al. The synthesis of azadirachtin: a potent insect antifeedant. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 10683-704. PMID 18821532 DOI: 10.1002/Chem.200801103  0.803
2008 Bridgwood KL, Tzschucke CC, O'Brien M, Wittrock S, Goodman JM, Davies JE, Logan AW, Hüttl MR, Ley SV. Enantiopure 2-substituted glyceraldehyde derivatives by aza-Claisen rearrangement or C-alkylation of enamines. Organic Letters. 10: 4537-40. PMID 18816124 DOI: 10.1021/Ol8018242  0.793
2008 Baxendale IR, Ley SV, Smith CD, Tamborini L, Voica AF. A bifurcated pathway to thiazoles and imidazoles using a modular flow microreactor. Journal of Combinatorial Chemistry. 10: 851-7. PMID 18783277 DOI: 10.1021/Cc800070A  0.55
2008 Bridgwood KL, Veitch GE, Ley SV. Magnesium nitride as a convenient source of ammonia: preparation of dihydropyridines. Organic Letters. 10: 3627-9. PMID 18642824 DOI: 10.1021/Ol801399W  0.344
2008 Veitch GE, Bridgwood KL, Ley SV. Magnesium nitride as a convenient source of ammonia: preparation of primary amides. Organic Letters. 10: 3623-5. PMID 18642822 DOI: 10.1021/Ol801398Z  0.319
2008 Wascholowski V, Knudsen KR, Mitchell CE, Ley SV. A general organocatalytic enantioselective malonate addition to alpha,beta-unsaturated enones. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 6155-65. PMID 18512863 DOI: 10.1002/Chem.200800673  0.373
2008 Baumann M, Baxendale IR, Ley SV, Nikbin N, Smith CD. Azide monoliths as convenient flow reactors for efficient Curtius rearrangement reactions. Organic & Biomolecular Chemistry. 6: 1587-93. PMID 18421390 DOI: 10.1039/B801634H  0.565
2008 Baumann M, Baxendale IR, Ley SV, Nikbin N, Smith CD, Tierney JP. A modular flow reactor for performing Curtius rearrangements as a continuous flow process. Organic & Biomolecular Chemistry. 6: 1577-86. PMID 18421389 DOI: 10.1039/B801631N  0.539
2008 Maddess ML, Tackett MN, Ley SV. Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. ProgrèS Des Recherches Pharmaceutiques. 66: 13, 15-186. PMID 18416305 DOI: 10.1007/978-3-7643-8595-8_2  0.359
2008 O'Brien M, Diéguez-Vázquez A, Hsu DS, Kraus H, Sumino Y, Ley SV. Azeotropic reflux chromatography: an efficient solution to a difficult separation in the scale-up synthesis of spongistatin 1. Organic & Biomolecular Chemistry. 6: 1159-64. PMID 18362951 DOI: 10.1039/B719569A  0.325
2008 Raja R, Thomas JM, Greenhill-Hooper M, Ley SV, Almeida Paz FA. Facile, one-step production of niacin (vitamin B3) and other nitrogen-containing pharmaceutical chemicals with a single-site heterogeneous catalyst. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 2340-8. PMID 18228543 DOI: 10.1002/Chem.200701679  0.305
2008 Veitch GE, Pinto A, Boyer A, Beckmann E, Anderson JC, Ley SV. Synthesis of natural products from the Indian neem tree Azadirachta indica. Organic Letters. 10: 569-72. PMID 18193879 DOI: 10.1021/Ol7027898  0.798
2008 Diéguez-Vázquez A, Tzschucke CC, Lam WY, Ley SV. PtCl4-catalyzed domino synthesis of fused bicyclic acetals. Angewandte Chemie (International Ed. in English). 47: 209-12. PMID 18061909 DOI: 10.1002/Anie.200704595  0.728
2008 Baumann M, Baxendale IR, Ley SV. The use of diethylaminosulfur trifluoride (DAST) for fluorination in a continuous-flow microreactor Synlett. 2111-2114. DOI: 10.1055/S-2008-1078026  0.317
2008 Hopkin MD, Baxendale IR, Ley SV. Synthesis of Pyrroloisoquinolines via Multicomponent Condensation Synfacts. 2008: 803-803. DOI: 10.1055/S-2008-1077934  0.418
2008 Tzschucke CC, Pradidphol N, Diéguez-Vázquez A, Kongkathip B, Kongkathip N, Ley SV. FeCl3-catalysed cleavage of 1,2-butanediacetal protected diols Synlett. 1293-1296. DOI: 10.1055/S-2008-1072752  0.658
2008 Hopkin MD, Baxendale IR, Ley SV. A new focused microwave approach to the synthesis of amino-substituted pyrroloisoquinolines and pyrroloquinolines via a sequential multi-component coupling process Synthesis. 1688-1702. DOI: 10.1055/S-2008-1067048  0.407
2008 Wascholowski V, Hansen HM, Longbottom DA, Ley SV. A general organocatalytic enantioselective nitrocyclopropanation reaction Synthesis. 1269-1275. DOI: 10.1055/S-2008-1042944  0.427
2008 Veitch GE, Beckmann E, Burke BJ, Boyer A, Maslen SL, Ley SV. Relay Synthesis of Azadirachtin Synfacts. 2008: 111-111. DOI: 10.1055/S-2007-992496  0.38
2008 Veitch GE, Bridgwood KL, Rands-Trevor K, Ley SV. Magnesium nitride as a convenient source of ammonia: Preparation of pyrroles Synlett. 2597-2600. DOI: 10.1055/S-0028-1083504  0.361
2008 Ley S, Veitch G, Bridgwood K. Simple Conversion of Esters to Primary Amides Using Magnesium Nitride Synfacts. 2008: 1212-1212. DOI: 10.1055/S-0028-1083455  0.313
2008 Leyva A, Blum FE, Ley SV. A new synthesis of (-)-epipyriculol: a phytotoxic metabolite Tetrahedron. 64: 4711-4717. DOI: 10.1016/J.Tet.2008.01.115  0.394
2008 Leyva A, Blum FE, Hewitt PR, Ley SV. Functionalised butanediacetal-protected 1,2-diols as suitable partners for Pd-catalysed cross-coupling reactions Tetrahedron. 64: 2348-2358. DOI: 10.1016/J.Tet.2008.01.010  0.349
2008 Åberg G, Aigbirhio FI, Alexakis E, Al-Maharik N, Almi M, Ambacher Y, Andersson S, Athlan A, Badman G, Baldwin SA, Baumann M, Baxendale IR, Botting NP, Bragg RA, Brown JA, ... ... Ley SV, et al. 16th International Isotope Society (UK group) Symposium Journal of Labelled Compounds and Radiopharmaceuticals. 51: 247-261. DOI: 10.1002/Jlcr.1513  0.625
2008 Tzschucke CC, Pradidphol N, Dieguez-Vazquez A, Kongkathip B, Kongkathip N, Ley SV. ChemInform Abstract: FeCl3-Catalyzed Cleavage of 1,2-Butanediacetal Protected Diols. Cheminform. 39. DOI: 10.1002/chin.200840054  0.651
2008 Ley SV, Baxendale IR, Myers RM. ChemInform Abstract: Polymer-Supported Reagents and Scavengers in Synthesis Cheminform. 39. DOI: 10.1002/chin.200835258  0.681
2008 Ley S, Abad-Somovilla A, Anderson J, Ayats C, Bänteli R, Beckmann E, Boyer A, Brasca M, Brice A, Broughton H, Burke B, Cleator E, Craig D, Denholm A, Denton R, et al. Cover Picture: The Synthesis of Azadirachtin: A Potent Insect Antifeedant (Chem. Eur. J. 34/2008) Chemistry - a European Journal. 14: 10503-10503. DOI: 10.1002/Chem.200890139  0.798
2008 Fukuyama T, Rahman MT, Ryu I, Baxendale IR, Hayward JJ, Lanners S, Ley SV, Smith CD, Ahmed-Omer B, Wirth T, Hessel V, Löb P, Löwe H, Koch K, Rutjes FPJT, et al. Organic Chemistry in Microreactors Microreactors in Organic Synthesis and Catalysis. 59-209. DOI: 10.1002/9783527622856.ch4  0.37
2008 Aureggi V, Franckevičius V, Kitching MO, Ley SV, Longbottom DA, Oelke AJ, Sedelmeier G. (S)‐5‐Pyrrolidin‐2‐Yl‐1H‐Tetrazole Organic Syntheses. 72-87. DOI: 10.1002/0471264229.Os085.09  0.691
2007 Baxendale IR, Hayward JJ, Ley SV. Microwave reactions under continuous flow conditions. Combinatorial Chemistry & High Throughput Screening. 10: 802-36. PMID 18288946 DOI: 10.2174/138620707783220374  0.388
2007 Kumarn S, Oelke AJ, Shaw DM, Longbottom DA, Ley SV. A sequential enantioselective, organocatalytic route to chiral 1,2-oxazines and chiral pyridazines. Organic & Biomolecular Chemistry. 5: 2678-89. PMID 18019543 DOI: 10.1039/B708646F  0.367
2007 Smith CJ, Iglesias-Sigüenza FJ, Baxendale IR, Ley SV. Flow and batch mode focused microwave synthesis of 5-amino-4-cyanopyrazoles and their further conversion to 4-aminopyrazolopyrimidines. Organic & Biomolecular Chemistry. 5: 2758-61. PMID 17700841 DOI: 10.1039/B709043A  0.354
2007 Veitch GE, Beckmann E, Burke BJ, Boyer A, Maslen SL, Ley SV. Synthesis of azadirachtin: a long but successful journey. Angewandte Chemie (International Ed. in English). 46: 7629-32. PMID 17665403 DOI: 10.1002/Anie.200703027  0.773
2007 Veitch GE, Beckmann E, Burke BJ, Boyer A, Ayats C, Ley SV. A relay route for the synthesis of azadirachtin. Angewandte Chemie (International Ed. in English). 46: 7633-5. PMID 17665383 DOI: 10.1002/Anie.200703028  0.781
2007 Smith CD, Baxendale IR, Tranmer GK, Baumann M, Smith SC, Lewthwaite RA, Ley SV. Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor. Organic & Biomolecular Chemistry. 5: 1562-8. PMID 17571185 DOI: 10.1039/B703033A  0.544
2007 Smith CD, Baxendale IR, Lanners S, Hayward JJ, Smith SC, Ley SV. [3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor. Organic & Biomolecular Chemistry. 5: 1559-61. PMID 17571184 DOI: 10.1039/B702995K  0.522
2007 Andrews SP, Ball M, Wierschem F, Cleator E, Oliver S, Högenauer K, Simic O, Antonello A, Hünger U, Smith MD, Ley SV. Total synthesis of five thapsigargins: guaianolide natural products exhibiting sub-nanomolar SERCA inhibition. Chemistry (Weinheim An Der Bergstrasse, Germany). 13: 5688-712. PMID 17508363 DOI: 10.1002/Chem.200700302  0.519
2007 Andrews SP, Tait MM, Ball M, Ley SV. Design and total synthesis of unnatural analogues of the sub-nanomolar SERCA inhibitor thapsigargin. Organic & Biomolecular Chemistry. 5: 1427-36. PMID 17464412 DOI: 10.1039/B702481A  0.345
2007 Bull JA, Balskus EP, Horan RA, Langner M, Ley SV. Total synthesis of potent antifungal marine bisoxazole natural products bengazoles A and B. Chemistry (Weinheim An Der Bergstrasse, Germany). 13: 5515-38. PMID 17440905 DOI: 10.1002/Chem.200700033  0.42
2007 Ley SV, Polara A. A fascination with 1,2-diacetals. The Journal of Organic Chemistry. 72: 5943-59. PMID 17430000 DOI: 10.1021/Jo0703451  0.4
2007 Griffiths-Jones CM, Hopkin MD, Jönsson D, Ley SV, Tapolczay DJ, Vickerstaffe E, Ladlow M. Fully automated flow-through synthesis of secondary sulfonamides in a binary reactor system. Journal of Combinatorial Chemistry. 9: 422-30. PMID 17348713 DOI: 10.1021/Cc060152B  0.4
2007 Milroy LG, Zinzalla G, Prencipe G, Michel P, Ley SV, Gunaratnam M, Beltran M, Neidle S. Chemical variation of natural-product-like scaffolds: Design, synthesis, and biological activity of fused bicyclic acetal derivatives Angewandte Chemie - International Edition. 46: 2493-2496. PMID 17318936 DOI: 10.1002/Anie.200604688  0.363
2007 Ball M, Andrews SP, Wierschem F, Cleator E, Smith MD, Ley SV. Total synthesis of thapsigargin, a potent SERCA pump inhibitor. Organic Letters. 9: 663-6. PMID 17256950 DOI: 10.1021/Ol062947X  0.563
2007 Maddess ML, Tackett MN, Watanabe H, Brennan PE, Spilling CD, Scott JS, Osborn DP, Ley SV. Total synthesis of rapamycin. Angewandte Chemie (International Ed. in English). 46: 591-7. PMID 17154218 DOI: 10.1002/Anie.200604053  0.653
2007 Longbottom DA, Franckevicius V, Ley SV. (S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric Organocatalysts of Broad Utility in Organic Synthesis Cheminform. 38. DOI: 10.2533/Chimia.2007.247  0.363
2007 Ley SV, Sheppard TD, Myers RM, Chorghade MS. Chiral glycolate equivalents for the asymmetric synthesis of α-hydroxycarbonyl compounds Bulletin of the Chemical Society of Japan. 80: 1451-1472. DOI: 10.1246/Bcsj.80.1451  0.81
2007 Andrews SP, Ball M, Wierschem F, Cleator E, Oliver S, Högenauer K, Simic O, Antonello A, Hünger U, Smith MD, Ley SV. Synthesis of Thapsigargin Synfacts. 2007: 1229-1229. DOI: 10.1055/S-2007-991303  0.561
2007 Vickerstaffe E, Villard A, Ladlow M, Ley SV. Chromatography-Free Suzuki Reactions Using a Polymer-Assisted Solution-Phase (PASP) Approach. Cheminform. 38. DOI: 10.1055/S-2007-977457  0.352
2007 Ley S, Baxendale I, Smith C, Tranmer G. Synthesis of Di- and Tripeptides Using A Flow Process Synfacts. 2007: 0441-0441. DOI: 10.1055/S-2007-968300  0.356
2007 Ley S, Bull J, Balskus E, Horan R, Langner M. Synthesis of Bengazole A Synfacts. 2007: 0351-0351. DOI: 10.1055/S-2007-968283  0.411
2007 Oelke AJ, Kumarn S, Longbottom DA, Ley SV. An Enantioselective Organocatalytic Route to Chiral 3,6-Dihydropyridazines from Aldehydes. Cheminform. 38. DOI: 10.1055/S-2006-951486  0.391
2007 Nikbin N, Ladlow M, Ley SV. Continuous Flow Ligand-Free Heck Reactions Using Monolithic Pd [0] Nanoparticles Organic Process Research & Development. 11: 458-462. DOI: 10.1021/Op7000436  0.3
2007 Hornung CH, Mackley MR, Baxendale IR, Ley SV. A Microcapillary Flow Disc Reactor for Organic Synthesis Organic Process Research & Development. 11: 399-405. DOI: 10.1021/Op700015F  0.377
2007 Andrews S, Ball M, Wierschem F, Cleator E, Oliver S, Högenauer K, Simic O, Antonello A, Hünger U, Smith M, Ley S. Cover Picture: Total Synthesis of Five Thapsigargins: Guaianolide Natural Products Exhibiting Sub-Nanomolar SERCA Inhibition (Chem. Eur. J. 20/2007) Chemistry - a European Journal. 13: 5657-5657. DOI: 10.1002/Chem.200790070  0.502
2007 Veitch G, Beckmann E, Burke B, Boyer A, Maslen S, Ley S. Cover Picture: Synthesis of Azadirachtin: A Long but Successful Journey (Angew. Chem. Int. Ed. 40/2007) Angewandte Chemie International Edition. 46: 7519-7519. DOI: 10.1002/Anie.200790198  0.331
2007 Veitch G, Beckmann E, Burke B, Boyer A, Maslen S, Ley S. Titelbild: Synthesis of Azadirachtin: A Long but Successful Journey (Angew. Chem. 40/2007) Angewandte Chemie. 119: 7663-7663. DOI: 10.1002/Ange.200790198  0.342
2007 Knudsen KR, Holden J, Ley S, Ladlow M. Optimisation of Conditions forO-Benzyl andN-Benzyloxycarbonyl Protecting Group Removal using an Automated Flow Hydrogenator Advanced Synthesis & Catalysis. 349: 535-538. DOI: 10.1002/Adsc.200600558  0.305
2006 Hansen HM, Longbottom DA, Ley SV. A new asymmetric organocatalytic nitrocyclopropanation reaction. Chemical Communications (Cambridge, England). 4838-40. PMID 17345746 DOI: 10.1039/B612436B  0.349
2006 Baxendale IR, Ley SV, Smith CD, Tranmer GK. A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols. Chemical Communications (Cambridge, England). 4835-7. PMID 17345745 DOI: 10.1039/B612197G  0.539
2006 Baumann M, Baxendale IR, Ley SV, Smith CD, Tranmer GK. Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles. Organic Letters. 8: 5231-4. PMID 17078685 DOI: 10.1021/Ol061975C  0.589
2006 Kumarn S, Shaw DM, Ley SV. A highly selective, organocatalytic route to chiral 1,2-oxazines from ketones. Chemical Communications (Cambridge, England). 3211-3. PMID 17028746 DOI: 10.1039/B606338A  0.403
2006 Bull JA, Balskus EP, Horan RA, Langner M, Ley SV. Stereocontrolled total synthesis of bengazole a: a marine bisoxazole natural product displaying potent antifungal properties. Angewandte Chemie (International Ed. in English). 45: 6714-8. PMID 16986186 DOI: 10.1002/Anie.200602050  0.359
2006 Johansson CC, Bremeyer N, Ley SV, Owen DR, Smith SC, Gaunt MJ. Enantioselective catalytic intramolecular cyclopropanation using modified cinchona alkaloid organocatalysts. Angewandte Chemie (International Ed. in English). 45: 6024-8. PMID 16888822 DOI: 10.1002/Anie.200602129  0.576
2006 Baxendale IR, Deeley J, Griffiths-Jones CM, Ley SV, Saaby S, Tranmer GK. A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly. Chemical Communications (Cambridge, England). 2566-8. PMID 16779479 DOI: 10.1039/B600382F  0.407
2006 Mitchell CE, Brenner SE, García-Fortanet J, Ley SV. An efficient, asymmetric organocatalyst-mediated conjugate addition of nitroalkanes to unsaturated cyclic and acyclic ketones. Organic & Biomolecular Chemistry. 4: 2039-49. PMID 16688349 DOI: 10.1039/B601877G  0.646
2006 Zinzalla G, Milroy LG, Ley SV. Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives. Organic & Biomolecular Chemistry. 4: 1977-2002. PMID 16688343 DOI: 10.1039/B603015G  0.402
2006 Pepys MB, Hirschfield GM, Tennent GA, Gallimore JR, Kahan MC, Bellotti V, Hawkins PN, Myers RM, Smith MD, Polara A, Cobb AJ, Ley SV, Aquilina JA, Robinson CV, Sharif I, et al. Targeting C-reactive protein for the treatment of cardiovascular disease. Nature. 440: 1217-21. PMID 16642000 DOI: 10.1038/Nature04672  0.719
2006 Tate EW, Dixon DJ, Ley SV. A highly enantioselective total synthesis of (+)-goniodiol. Organic & Biomolecular Chemistry. 4: 1698-706. PMID 16633562 DOI: 10.1039/B602805E  0.725
2006 Knudsen KR, Stepan AF, Michel P, Ley SV. Diastereoselective aldol reactions with butane-2,3-diacetal protected glyceraldehyde derivatives. Organic & Biomolecular Chemistry. 4: 1471-3. PMID 16604212 DOI: 10.1039/B601888B  0.418
2006 Baxendale IR, Griffiths-Jones CM, Ley SV, Tranmer GK. Microwave-assisted Suzuki coupling reactions with an encapsulated palladium catalyst for batch and continuous-flow transformations. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 4407-16. PMID 16586523 DOI: 10.1002/Chem.200501400  0.38
2006 Sneddon HF, van den Heuvel A, Hirsch AK, Booth RA, Shaw DM, Gaunt MJ, Ley SV. Double conjugate addition of dithiols to propargylic carbonyl systems to generate protected 1,3-dicarbonyl compounds. The Journal of Organic Chemistry. 71: 2715-25. PMID 16555825 DOI: 10.1021/Jo052514S  0.78
2006 Knudsen KR, Mitchell CE, Ley SV. Asymmetric organocatalytic conjugate addition of malonates to enones using a proline tetrazole catalyst. Chemical Communications (Cambridge, England). 66-8. PMID 16353094 DOI: 10.1039/B514636D  0.329
2006 Franckevičius V, Longbottom DA, Turner RM, Ley SV. 8,9,10,10a-tetrahydro-6H-tetrazolo[1,5-a]pyrrolo[2,1-c]pyrazines: New heterocyclic frameworks generated by an Ugi-type multicomponent reaction Synthesis. 3215-3223. DOI: 10.1055/S-2006-950219  0.365
2006 Gaunt M, Johansson C, Bremeyer N, Ley S, Owen D, Smith S. Enantioselective Intramolecular Cyclopro-panation Using Modified Cinchona Alkaloids Synfacts. 2006: 1059-1059. DOI: 10.1055/S-2006-949376  0.589
2006 Ley S, Baxendale I, Griffiths-Jones C, Tranmer G. A Continuous-Flow Process for Natural Product Synthesis Synfacts. 2006: 0622-0622. DOI: 10.1055/S-2006-941806  0.36
2006 Ley S, Franckevičius V, Knudsen K, Ladlow M, Longbottom D. Practical Synthesis of (S)-Pyrrolidin-2-yl-1H-tetrazole, Incorporating Efficient Protecting Group Removal by Flow-Reactor Hydrogenolysis Synlett. 2006: 889-892. DOI: 10.1055/S-2006-939036  0.374
2006 Baxendale IR, Griffiths-Jones CM, Ley SV, Tranmer GK. Preparation of the Neolignan Natural Product Grossamide by a Continuous-Flow Process. Cheminform. 37. DOI: 10.1055/S-2006-926244  0.374
2006 Grice P, Ley SV, Pietruszka J, Osborn HMI, Priepke HWM, Warriner SL. A New Strategy for Oligosaccharide Assembly Exploiting Cyclohexane-1,2-diacetal Methodology: An Efficient Synthesis of a High Mannose Type Nonasaccharide Chemistry - a European Journal. 3: 431-440. DOI: 10.1002/Chem.19970030315  0.338
2005 Ley SV, Dixon DJ, Guy RT, Rodríguez F, Sheppard TD. Michael, Michael-aldol and Michael-Michael reactions of enolate equivalents of butane-2,3-diacetal protected glycolic acid derivatives. Organic & Biomolecular Chemistry. 3: 4095-107. PMID 16267589 DOI: 10.1039/B512410G  0.726
2005 Søhoel H, Liljefors T, Ley SV, Oliver SF, Antonello A, Smith MD, Olsen CE, Isaacs JT, Christensen SB. Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase inhibitors designed by an analysis of the binding site of thapsigargin. Journal of Medicinal Chemistry. 48: 7005-11. PMID 16250659 DOI: 10.1021/Jm058036V  0.45
2005 Mitchell CE, Brenner SE, Ley SV. A versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones. Chemical Communications (Cambridge, England). 5346-8. PMID 16244750 DOI: 10.1039/B511441A  0.623
2005 Kumarn S, Shaw DM, Longbottom DA, Ley SV. A highly selective, organocatalytic route to chiral dihydro-1,2-oxazines. Organic Letters. 7: 4189-91. PMID 16146384 DOI: 10.1021/Ol051577U  0.43
2005 Siu J, Baxendale IR, Lewthwaite RA, Ley SV. A phase-switch purification approach for the expedient removal of tagged reagents and scavengers following their application in organic synthesis Organic and Biomolecular Chemistry. 3: 3140-3160. PMID 16106295 DOI: 10.1039/B503778F  0.342
2005 Ball M, Gaunt MJ, Hook DF, Jessiman AS, Kawahara S, Orsini P, Scolaro A, Talbot AC, Tanner HR, Yamanoi S, Ley SV. Total synthesis of spongistatin 1: a synthetic strategy exploiting its latent pseudo-symmetry. Angewandte Chemie (International Ed. in English). 44: 5433-8. PMID 16059947 DOI: 10.1002/Anie.200502008  0.579
2005 Baxendale IR, Ley SV. Formation of 4-aminopyrimidines via the trimerization of nitriles using focused microwave heating. Journal of Combinatorial Chemistry. 7: 483-9. PMID 15877477 DOI: 10.1021/Cc049826D  0.363
2005 Lee CK, Holmes AB, Ley SV, McConvey IF, Al-Duri B, Leeke GA, Santos RC, Seville JP. Efficient batch and continuous flow Suzuki cross-coupling reactions under mild conditions, catalysed by polyurea-encapsulated palladium (II) acetate and tetra-n-butylammonium salts. Chemical Communications (Cambridge, England). 2175-7. PMID 15846438 DOI: 10.1039/B418669A  0.349
2005 Brittain DE, Griffiths-Jones CM, Linder MR, Smith MD, McCusker C, Barlow JS, Akiyama R, Yasuda K, Ley SV. Total synthesis of antascomicin B. Angewandte Chemie (International Ed. in English). 44: 2732-7. PMID 15806607 DOI: 10.1002/Anie.200500174  0.492
2005 Burke LT, Dixon DJ, Ley SV, Rodríguez F. Total synthesis of the Fusarium toxin equisetin. Organic & Biomolecular Chemistry. 3: 274-80. PMID 15632969 DOI: 10.1039/B411350K  0.561
2005 Cobb AJ, Shaw DM, Longbottom DA, Gold JB, Ley SV. Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions. Organic & Biomolecular Chemistry. 3: 84-96. PMID 15602602 DOI: 10.1039/B414742A  0.381
2005 Nattrass GL, Díez E, McLachlan MM, Dixon DJ, Ley SV. The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin. Angewandte Chemie (International Ed. in English). 44: 580-4. PMID 15597387 DOI: 10.1002/Anie.200462264  0.6
2005 Ley SV. Development of Methods Suitable for Natural Product Synthesis: The Azadirachtin Story Cheminform. 36. DOI: 10.1351/Pac200577071115  0.424
2005 Ley SV. Development of methods suitable for natural product synthesis: The azadirachtin story Pure and Applied Chemistry. 77: 1115-1130. DOI: 10.1351/pac200577071115  0.313
2005 Kumarn S, Shaw DM, Longbottom DA, Ley SV. A One-Pot Synthesis of Chiral Dihydro-1,2-oxazines Synfacts. 2005: 346-346. DOI: 10.1055/S-2005-921647  0.387
2005 Saaby S, Baxendale IR, Ley SV. [2+2+2] Cyclotrimerization to Benzofurans, Benzothiophenes and Isoindoles Synfacts. 2005: 297-297. DOI: 10.1055/S-2005-921584  0.368
2005 Kawahara S, Gaunt MJ, Scolaro A, Yamanoi S, Ley SV. Synthesis of the EF fragment of spongistatin 1 Synlett. 2031-2034. DOI: 10.1055/S-2005-871960  0.531
2005 Lohmann S, Andrews SP, Burke BJ, Smith MD, Attfield JP, Tanaka H, Kaneko K, Ley SV. Copper- and palladium-containing perovskites: Catalysts for the Ullmann and Sonogashira reactions Synlett. 1291-1295. DOI: 10.1055/S-2005-865233  0.518
2005 Evans AC, Longbottom DA, Matsuoka M, Ley SV. Highly Diastereoselective Desymmetrization of Cyclic meso-Anhydrides and Derivatization to Mono-Protected 1,4-Diols. Cheminform. 36. DOI: 10.1055/S-2005-862393  0.397
2005 Mitchell CET, Cobb AJA, Ley SV. A homo-proline tetrazole as an improved organocatalyst for the asymmetric Michael addition of carbonyl compounds to nitro-olefins Synlett. 611-614. DOI: 10.1055/S-2005-862392  0.356
2005 Dixon DJ, Ley SV, Lohmann S, Sheppard TD. Synthesis of a ceramide sphingolipid as a potential sex pheromone of the hair crab Erimacrus isenbeckii using butane-2,3-diacetal desymmetrised glycolic acid building blocks Synlett. 481-484. DOI: 10.1055/S-2005-862361  0.73
2005 Baxendale IR, Ley SV. Synthesis of the Alkaloid Natural Products (+)-Plicane and (−)-Obliquine, Using Polymer-Supported Reagents and Scavengers† Industrial & Engineering Chemistry Research. 44: 8588-8592. DOI: 10.1021/Ie048822I  0.312
2005 Sharma G, Punna S, Hymavathi L, Reddy NY, Radha Krishna P, Chorghade MS, Ley SV. Stereoselective synthesis of (2R,3S,4S,5R)-trans-3,4-dihydroxy-5-(4-fluorophenoxymethyl)-2-(1-N-hydroxyureidyl-3-butyn-4-yl)tetrahydrofuran and (2R,3S,4S,5R)-trans-5-ethynyl-2-(4-fluorophenoxymethyl)-3,4-O-isopropylidene tetrahydrofuran from mannose diacetonide Tetrahedron: Asymmetry. 16: 1135-1140. DOI: 10.1016/J.Tetasy.2005.01.046  0.333
2005 Sharma G, Punna S, Radha Krishna P, Chorghade MS, Ley SV. Stereoselective synthesis of chiral tetrahydrofurans with potent 5-LO inhibitory activity Tetrahedron: Asymmetry. 16: 1125-1133. DOI: 10.1016/J.Tetasy.2005.01.045  0.437
2005 Sharma G, Punna S, Rajendra Prasad T, Radha Krishna P, Chorghade MS, Ley SV. Stereoselective syntheses of pharmaceutically relevant chiral tetrahydrofurans from (S)- and (R)-glyceraldehyde derivatives Tetrahedron: Asymmetry. 16: 1113-1123. DOI: 10.1016/J.Tetasy.2005.01.044  0.355
2005 Gurjar MK, Rao BV, Krishna LM, Chorghade MS, Ley SV. Stereoselective synthesis of (2S,7S)-7-(4-phenoxymethyl)-2-(1-N-hydroxyureidyl-3-butyn-4-yl)oxepane: a potential anti-asthmatic drug candidate Tetrahedron: Asymmetry. 16: 935-939. DOI: 10.1016/J.Tetasy.2005.01.024  0.379
2005 Baxendale IR, Ley SV, Martinelli M. The Rapid Preparation of 2-Aminosulfonamide-1,3,4-oxadiazoles Using Polymer-Supported Reagents and Microwave Heating. Cheminform. 36. DOI: 10.1016/J.Tet.2005.03.062  0.343
2005 Lohmann S, Andrews SP, Burke BJ, Smith MD, Attfield JP, Tanaka H, Kaneko K, Ley SV. Copper- and Palladium-Containing Perovskites: Catalysts for the Ullmann and Sonogashira Reactions. Cheminform. 36. DOI: 10.1002/chin.200542090  0.421
2005 Andrews SP, Stepan AF, Tanaka H, Ley SV, Smith MD. Heterogeneous or homogeneous? A case study involving palladium-containing perovskites in the Suzuki reaction Advanced Synthesis and Catalysis. 347: 647-654. DOI: 10.1002/Adsc.200404331  0.483
2004 Bremeyer N, Smith SC, Ley SV, Gaunt MJ. An intramolecular organocatalytic cyclopropanation reaction. Angewandte Chemie (International Ed. in English). 43: 2681-4. PMID 18629989 DOI: 10.1002/Anie.200454007  0.612
2004 Ley SV, Dixon DJ, Guy RT, Palomero MA, Polara A, Rodriguez F, Sheppard TD. Studies on the generation of enolate anions from butane-2,3-diacetal protected glycolic acid derivatives and subsequent highly diastereoselective coupling reactions with aldehydes and acid chlorides. Organic & Biomolecular Chemistry. 2: 3618-27. PMID 15592620 DOI: 10.1039/B412790K  0.723
2004 Ley SV, Diez E, Dixon DJ, Guy RT, Michel P, Nattrass GL, Sheppard TD. Preparation of enantiopure butane-2,3-diacetals of glycolic acid and alkylation reactions leading to alpha-hydroxyacid and amide derivatives. Organic & Biomolecular Chemistry. 2: 3608-17. PMID 15592619 DOI: 10.1039/B412788A  0.692
2004 Papageorgiou CD, Cubillo de Dios MA, Ley SV, Gaunt MJ. Enantioselective organocatalytic cyclopropanation via ammonium ylides. Angewandte Chemie (International Ed. in English). 43: 4641-4. PMID 15352192 DOI: 10.1002/Anie.200460234  0.575
2004 Hewitt PR, Cleator E, Ley SV. A concise total synthesis of (+)-okaramine C. Organic & Biomolecular Chemistry. 2: 2415-7. PMID 15326519 DOI: 10.1039/B410180D  0.348
2004 Cobb AJ, Longbottom DA, Shaw DM, Ley SV. 5-Pyrrolidin-2-yltetrazole as an asymmetric organocatalyst for the addition of ketones to nitro-olefins. Chemical Communications (Cambridge, England). 1808-9. PMID 15306894 DOI: 10.1039/B409646K  0.358
2004 Ley SV, Antonello A, Balskus EP, Booth DT, Christensen SB, Cleator E, Gold H, Högenauer K, Hünger U, Myers RM, Oliver SF, Simic O, Smith MD, Søhoel H, Woolford AJ. Synthesis of the thapsigargins. Proceedings of the National Academy of Sciences of the United States of America. 101: 12073-8. PMID 15226504 DOI: 10.1073/Pnas.0403300101  0.747
2004 Storer RI, Takemoto T, Jackson PS, Brown DS, Baxendale IR, Ley SV. Multi-step application of immobilized reagents and scavengers: A total synthesis of epothilone C Chemistry - a European Journal. 10: 2529-2547. PMID 15146525 DOI: 10.1002/Chem.200305669  0.382
2004 Vickerstaffe E, Warrington BH, Ladlow M, Ley SV. Fully automated polymer-assisted synthesis of 1,5-biaryl pyrazoles. Journal of Combinatorial Chemistry. 6: 332-9. PMID 15132592 DOI: 10.1021/Cc049977G  0.346
2004 Buffet MF, Dixon DJ, Ley SV, Reynolds DJ, Storer RI. Anomeric oxygen to carbon rearrangements of alkynyl tributylstannane derivatives of furanyl (gamma)- and pyranyl (delta)-lactols. Organic & Biomolecular Chemistry. 2: 1145-54. PMID 15064790 DOI: 10.1039/B316858A  0.528
2004 Ley SV, Michel P, Trapella C. A convenient route to enantiomerically pure 2-substituted methyl glycerate derivatives. Organic Letters. 5: 4553-5. PMID 14627381 DOI: 10.1021/Ol035567+  0.426
2004 Ley SV, Thomas AW. Modern synthetic methods for copper-mediated C(aryl)[bond]O, C(aryl)[bond]N, and C(aryl)[bond]S bond formation. Angewandte Chemie (International Ed. in English). 42: 5400-49. PMID 14618572 DOI: 10.1002/Anie.200300594  0.335
2004 Ley SV, Baxendale IR. Organic synthesis in a changing world. Chemical Record (New York, N.Y.). 2: 377-88. PMID 12469349 DOI: 10.1002/Tcr.10033  0.325
2004 Cleator E, Harter J, Ley SV. The Synthesis of (-)-Gloeosporone, a Potent Fungal Autoinhibitor of Spore Germination Using a π-Allyltricarbonylation Lactone Complex and a New Reductive Decomplexation Procedure for the Installation of the Embedded 1,7-Diol Component of the Natural Product. Cheminform. 35. DOI: 10.3987/Com-03-S(P)55  0.386
2004 Cobb AJA, Shaw DM, Ley SV. 5-Pyrrolidin-2-yltetrazole: A New, Catalytic, More Soluble Alternative to Proline in an Organocatalytic Asymmetric Mannich-Type Reaction. Cheminform. 35. DOI: 10.1055/S-2004-817745  0.337
2004 Siu J, Baxendale IR, Ley SV. Microwave-Assisted Leimgruber—Batcho Reaction for the Preparation of Indoles, Azaindoles and Pyrroylquinolines. Cheminform. 35. DOI: 10.1039/B313012F  0.424
2004 Cleator E, McCusker CF, Steltzer F, Ley SV. Grignard additions to 2-uloses: synthesis of stereochemically pure tertiary alcohols Tetrahedron Letters. 45: 3077-3080. DOI: 10.1016/J.Tetlet.2004.02.106  0.315
2004 Harding CI, Dixon DJ, Ley SV. The Preparation and Alkylation of a Butanedione-Derived Chiral Glycine Equivalent and Its Use for the Synthesis of α-Amino Acids and α,α-Disubstituted Amino Acids. Cheminform. 35. DOI: 10.1016/J.Tet.2004.06.063  0.553
2004 Harding CI, Dixon DJ, Ley SV. The preparation and alkylation of a butanedione-derived chiral glycine equivalent and its use for the synthesis of α-amino acids and α,α-disubstituted amino acids Tetrahedron. 60: 7679-7692. DOI: 10.1016/j.tet.2004.06.063  0.485
2004 Buffet MF, Dixon DJ, Ley SV, Reynolds DJ, Storer RI. Anomeric Oxygen to Carbon Rearrangements of Alkynyl Tributylstannane Derivatives of Furanyl (γ)- and Pyranyl (δ)-Lactols. Cheminform. 35. DOI: 10.1002/chin.200434039  0.444
2004 Storer RI, Takemoto T, Jackson PS, Brown DS, Baxendale IR, Ley SV. Cover Picture: Multi-Step Application of Immobilized Reagents and Scavengers: A Total Synthesis of Epothilone C (Chem. Eur. J. 10/2004) Chemistry - a European Journal. 10: 2355-2355. DOI: 10.1002/Chem.200490030  0.38
2003 Siu J, Baxendale IR, Ley SV. Microwave assisted Leimgruber-Batcho reaction for the preparation of indoles, azaindoles and pyrroylquinolines. Organic & Biomolecular Chemistry. 2: 160-7. PMID 14737637 DOI: 10.1039/b313012f  0.309
2003 Oliver SF, Högenauer K, Simic O, Antonello A, Smith MD, Ley SV. A route to the thapsigargins from (S)-carvone providing a substrate-controlled total synthesis of trilobolide, nortrilobolide, and thapsivillosin F. Angewandte Chemie (International Ed. in English). 42: 5996-6000. PMID 14679553 DOI: 10.1002/Anie.200353140  0.471
2003 Lee AL, Ley SV. The synthesis of the anti-malarial natural product polysphorin and analogues using polymer-supported reagents and scavengers Organic and Biomolecular Chemistry. 1: 3957-3966. PMID 14664385 DOI: 10.1039/B308761A  0.35
2003 Gaunt MJ, Jessiman AS, Orsini P, Tanner HR, Hook DF, Ley SV. Synthesis of the C-1-C-28 ABCD unit of spongistatin 1. Organic Letters. 5: 4819-22. PMID 14653682 DOI: 10.1021/Ol035849+  0.568
2003 Gaunt MJ, Hook DF, Tanner HR, Ley SV. A practical and efficient synthesis of the C-16-C-28 spiroketal fragment (CD) of the spongistatins. Organic Letters. 5: 4815-8. PMID 14653681 DOI: 10.1021/Ol035848H  0.568
2003 Smith MD, Stepan AF, Ramarao C, Brennan PE, Ley SV. Palladium-containing perovskites: recoverable and reuseable catalysts for Suzuki couplings. Chemical Communications (Cambridge, England). 2652-3. PMID 14649794 DOI: 10.1039/B308465E  0.467
2003 Ley SV, Cleator E, Harter J, Hollowood CJ. Synthesis of (-)-gloeosporone, a fungal autoinhibitor of spore germination using a pi-allyltricarbonyliron lactone complex as a templating architecture for 1,7-diol construction. Organic & Biomolecular Chemistry. 1: 3263-4. PMID 14584786 DOI: 10.1039/B308793J  0.389
2003 Hollowood CJ, Ley SV, Wright EA. 1,5-asymmetric induction of chirality using pi-allyltricarbonyliron lactone complexes: highly diastereoselective synthesis of alpha-functionalised carbonyl compounds. Organic & Biomolecular Chemistry. 1: 3208-16. PMID 14527153 DOI: 10.1039/B306862E  0.406
2003 MacCoss RN, Brennan PE, Ley SV. Synthesis of carbohydrate derivatives using solid-phase work-up and scavenging techniques. Organic & Biomolecular Chemistry. 1: 2029-31. PMID 12945889 DOI: 10.1039/B303951J  0.324
2003 Gaunt MJ, Sneddon HF, Hewitt PR, Orsini P, Hook DF, Ley SV. Development of beta-keto 1,3-dithianes as versatile intermediates for organic synthesis. Organic & Biomolecular Chemistry. 1: 15-6. PMID 12929380 DOI: 10.1002/chin.200321136  0.517
2003 Hollowood CJ, Yamanoi S, Ley SV. Use of pi-allyltricarbonyliron lactone complexes in the synthesis of taurospongin A: a potent inhibitor of DNA polymerase beta and HIV revers transcriptase. Organic & Biomolecular Chemistry. 1: 1664-75. PMID 12926353 DOI: 10.1039/B301676P  0.32
2003 Storer RI, Takemoto T, Jackson PS, Ley SV. A total synthesis of epothilones using solid-supported reagents and scavengers Angewandte Chemie - International Edition. 42: 2521-2525. PMID 12800176 DOI: 10.1002/Anie.200351413  0.417
2003 Yu JQ, Wu HC, Ramarao C, Spencer JB, Ley SV. Transfer hydrogenation using recyclable polyurea-encapsulated palladium: efficient and chemoselective reduction of aryl ketones. Chemical Communications (Cambridge, England). 678-9. PMID 12703769 DOI: 10.1039/B300074P  0.311
2003 Sneddon HF, Gaunt MJ, Ley SV. Addition of dithiols to bis-ynones: development of a versatile platform for the synthesis of polyketide natural products. Organic Letters. 5: 1147-50. PMID 12659595 DOI: 10.1021/Ol034248F  0.614
2003 Dixon DJ, Harding CI, Ley SV, Tilbrook DM. A 2,3-butanedione protected chiral glycine equivalent--a new building block for the stereoselective synthesis of enantiopure N-protected alpha-amino acids. Chemical Communications (Cambridge, England). 468-9. PMID 12638953 DOI: 10.1039/B210673F  0.577
2003 Papageorgiou CD, Ley SV, Gaunt MJ. Organic-catalyst-mediated cyclopropanation reaction. Angewandte Chemie (International Ed. in English). 42: 828-31. PMID 12596214 DOI: 10.1002/Anie.200390222  0.525
2003 Scicinski JJ, Congreveb MS, Kay C, Ley SV. Analytical techniques for small molecule solid phase synthesis. Current Medicinal Chemistry. 9: 2103-27. PMID 12470250 DOI: 10.2174/0929867023368737  0.321
2003 Ley SV, Taylor SJ. A polymer-supported [1,3,2]oxazaphospholidine for the conversion of isothiocyanates to isocyanides and their subsequent use in an ugi reaction. Bioorganic & Medicinal Chemistry Letters. 12: 1813-6. PMID 12086823 DOI: 10.1016/S0960-894X(02)00269-X  0.33
2003 Diez E, Dixon DJ, Ley SV, Polara A, Rodriguez F. Total Synthesis of the Phytotoxic Agent Herbarumin II Using Butane Diacetals of Glycolic Acid as Building Blocks. Cheminform. 34. DOI: 10.1055/S-2003-39892  0.543
2003 Baxendale IR, Ernst M, Krahnert W, Ley SV. Application of Polymer-Supported Enzymes and Reagents in the Synthesis of γ-Aminobutyric Acid (GABA) Analogues. Cheminform. 34. DOI: 10.1055/S-2002-34249  0.343
2003 Hirschfield GM, Smith MD, Ley SV, Kolstoe S, Thompson D, Wood SP, Pepys MB. Therapeutic Inhibition of C-Reactive Protein-Novel Drugs, Novel Mechanisms Clinical Science. 104. DOI: 10.1042/Cs104065Pb  0.434
2003 Gaunt MJ, Sneddon HF, Hewitt PR, Orsini P, Hook DF, Ley SV. Development of β-keto 1,3-dithianes as versatile intermediates for organic synthesis Organic and Biomolecular Chemistry. 1: 15-16. DOI: 10.1039/b208982c  0.473
2003 Bream RN, Ley SV, McDermott B, Procopiou PA. A Mild, Enantioselective Synthesis of (R)-Salmeterol via Sodium Borohydride—Calcium Chloride Asymmetric Reduction of a Phenacyl Phenylglycinol Derivative. Cheminform. 34. DOI: 10.1039/B207068P  0.359
2003 Baxendale IR, Lee A, Ley SV. A Concise Synthesis of Carpanone Using Solid-Supported Reagents and Scavengers. Cheminform. 34. DOI: 10.1039/B203388G  0.344
2003 Congreve MS, Kay C, Scicinski JJ, Ley SV, Williams G, Murray PJ, McKeown SC, Watson SP. Versatile solid-phase synthesis of secondary amines from alcohols. Development of an N-Boc-(o-nitrobenzene)sulfonamide linker Tetrahedron Letters. 44: 4153-4156. DOI: 10.1016/S0040-4039(03)00574-4  0.339
2003 Longbottom DA, Morrison AJ, Dixon DJ, Ley SV. Total Synthesis of the Polyenoyltetramic Acid Polycephalin C. Cheminform. 34. DOI: 10.1016/S0040-4020(03)00816-0  0.622
2003 Longbottom DA, Morrison AJ, Dixon DJ, Ley SV. Total synthesis of the polyenoyltetramic acid polycephalin C Tetrahedron. 59: 6955-6966. DOI: 10.1016/S0040-4020(03)00816-0  0.515
2003 Díez E, Dixon D, Ley S, Polara A, Rodríguez F. The Use of Butane Diacetals of Glycolic Acid as Precursors for the Synthesis of the Phytotoxic Calmodulin Inhibitor Herbarumin II Helvetica Chimica Acta. 86: 3717-3729. DOI: 10.1002/Hlca.200390314  0.602
2003 Dixon DJ, Guarna A, Ley SV, Polara A, Rodriguez F. Highly Diastereoselective Ketone Aldol Reactions of Butane-2,3-diacetal Desymmetrized Glycolic Acid. Cheminform. 34. DOI: 10.1002/chin.200306089  0.535
2003 Dixon DJ, Ley SV, Longbottom DA. Copper(I)‐Catalyzed Preparation of (E)‐3‐Iodoprop‐2‐enoic Acid Organic Syntheses. 80: 129-132. DOI: 10.1002/0471264180.Os080.15  0.513
2003 Ley SV, Osborn HMI. Methyl 2,3‐O‐(6,6′‐Octahydro‐6,6′‐Bi‐2H‐Pyran‐2,2′‐Diyl)‐α‐D‐Galactopyranoside Organic Syntheses. 212-212. DOI: 10.1002/0471264180.Os077.22  0.34
2003 Brown DS, Ley SV. Substitution Reactions of 2‐Benzenesulfonyl Cyclic Ethers: Tetrahydro‐2‐(Phenylethynyl)‐2H‐Pyran Organic Syntheses. 157-157. DOI: 10.1002/0471264180.Os070.18  0.387
2003 Fox CMJ, Ley SV. tert‐Butyl Acetothioacetate and Its Use in Synthesis: 3‐Acetyl‐4‐hydroxy‐5,5‐dimethylfuran‐2(4H)‐one Organic Syntheses. 108-108. DOI: 10.1002/0471264180.Os066.14  0.387
2002 Durand-Reville T, Gobbi LB, Gray BL, Ley SV, Scott JS. Highly Selective Entry to the Azadirachtin Skeleton via a Claisen Rearrangement/Radical Cyclization Sequence Organic Letters. 4: 3847-3850. PMID 12599474 DOI: 10.1021/Ol0201557  0.338
2002 Ley SV, Baxendale IR. New tools and concepts for modern organic synthesis. Nature Reviews. Drug Discovery. 1: 573-86. PMID 12402498 DOI: 10.1038/Nrd871  0.326
2002 Hollowood CJ, Ley SV. Reductive decomplexation of pi-allyltricarbonyliron lactone complexes; a new route to stereo-defined 1,7-diols and 2,3-diene-1,7-diols. Chemical Communications (Cambridge, England). 2130-1. PMID 12357809 DOI: 10.1039/B206406P  0.331
2002 Kiyota H, Dixon DJ, Luscombe CK, Hettstedt S, Ley SV. Synthesis, structure revision, and absolute configuration of (+)-didemniserinolipid B, a serinol marine natural product from a tunicate Didemnum sp. Organic Letters. 4: 3223-6. PMID 12227754 DOI: 10.1021/Ol026421Y  0.536
2002 Longbottom DA, Morrison AJ, Dixon DJ, Ley SV. Total synthesis of polycephalin C and determination of the absolute configurations at the 3",4" ring junction. Angewandte Chemie (International Ed. in English). 41: 2786-90. PMID 12203486 DOI: 10.1002/1521-3773(20020802)41:15<2786::Aid-Anie2786>3.0.Co;2-Z  0.571
2002 Hollowood CJ, Ley SV, Yamanoi S. Synthesis of taurospongin A: a potent inhibitor of DNA polymerase and HIV reverse transcriptase, using pi-allyltricarbonyliron lactone complexes. Chemical Communications (Cambridge, England). 1624-5. PMID 12170813 DOI: 10.1039/B204994P  0.327
2002 Ley SV, Ramarao C, Gordon RS, Holmes AB, Morrison AJ, McConvey IF, Shirley IM, Smith SC, Smith MD. Polyurea-encapsulated palladium(II) acetate: a robust and recyclable catalyst for use in conventional and supercritical media. Chemical Communications (Cambridge, England). 1134-5. PMID 12122701 DOI: 10.1039/B200677B  0.474
2002 Ley SV, Baxendale IR, Brusotti G, Caldarelli M, Massi A, Nesi M. Solid-supported reagents for multi-step organic synthesis: preparation and application. Farmaco (Societa Chimica Italiana : 1989). 57: 321-30. PMID 11989811 DOI: 10.1016/S0014-827X(02)01210-7  0.358
2002 Baxendale IR, Ley SV, Lumeras W, Nesi M. Synthesis of trifluoromethyl ketones using polymer-supported reagents. Combinatorial Chemistry & High Throughput Screening. 5: 197-9. PMID 11966427 DOI: 10.2174/1386207024607220  0.34
2002 Congreve MS, Ley SV, Scicinski JJ. Analytical construct resins for analysis of solid-phase chemistry. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 1768-76. PMID 11933104 DOI: 10.1002/1521-3765(20020415)8:8<1768::Aid-Chem1768>3.0.Co;2-J  0.351
2002 Dixon DJ, Ley SV, Reynolds DJ. The total synthesis of the annonaceous acetogenin, muricatetrocin C. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 1621-36. PMID 11933090 DOI: 10.1002/1521-3765(20020402)8:7<1621::Aid-Chem1621>3.0.Co;2-8  0.612
2002 Ley SV, Priour A, Heusser C. Total synthesis of the cyclic heptapeptide Argyrin B: a new potent inhibitor of T-cell independent antibody formation. Organic Letters. 4: 711-4. PMID 11869108 DOI: 10.1021/Ol017184M  0.374
2002 Dixon DJ, Ley SV, Rodríguez F. Highly diastereoselective Michael addition reactions of butane-2,3-diacetal desymmetrized glycolic acid. Preparation of alpha-hydroxy-gamma-amino acid derivatives. Organic Letters. 3: 3753-5. PMID 11700130 DOI: 10.1021/Ol016708F  0.555
2002 Dixon DJ, Ley SV, Polara A, Sheppard T. Highly diastereoselective lithium enolate aldol reactions of butane-2,3-diacetal desymmetrized glycolic acid and deprotection to enantiopure anti-2,3-dihydroxy esters. Organic Letters. 3: 3749-52. PMID 11700129 DOI: 10.1021/Ol016707N  0.727
2002 Ley SV, Myers RM. Sir Derek Harold Richard Barton. 8 September 1918 – 16 March 1998 Biographical Memoirs of Fellows of the Royal Society. 48: 1-23. DOI: 10.1098/Rsbm.2002.0001  0.664
2002 Ley S, Dixon D, Guarna A, Polara A, Rodríguez F. Highly Diastereoselective Ketone Aldol Reactions of Butane-2,3-diacetal Desymmetrised­ Glycolic Acid Synthesis. 2002. DOI: 10.1055/S-2002-34377  0.583
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