| Year |
Citation |
Score |
| 2020 |
Nilsson I, Lee SY, Sawyer WS, Baxter Rath CM, Lapointe G, Six D. Metabolic phospholipid labeling of intact bacteria enables a fluorescence assay that detects compromised outer membranes. Journal of Lipid Research. PMID 32156718 DOI: 10.1194/Jlr.Ra120000654 |
0.364 |
|
| 2019 |
Hamrick JC, Docquier JD, Uehara T, Myers CL, Six DA, Chatwin CL, John KJ, Vernacchio SF, Cusick SM, Trout REL, Pozzi C, De Luca F, Benvenuti M, Mangani S, Liu B, et al. VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- and metallo-β-lactamases, restores activity of cefepime in and . Antimicrobial Agents and Chemotherapy. PMID 31871094 DOI: 10.1128/Aac.01963-19 |
0.333 |
|
| 2019 |
Shen X, Johnson NV, Kreamer NNK, Barnes SW, Walker JR, Woods AL, Six DA, Dean CR. Genetic defects in efflux (), β-lactamase () and lipopolysaccharide transport () mediate antibiotic hypersusceptibility of strain Z61. Antimicrobial Agents and Chemotherapy. PMID 31036686 DOI: 10.1128/Aac.00784-19 |
0.339 |
|
| 2019 |
Widya M, Pasutti W, Sachdeva M, Simmons R, Tamrakar P, Krucker T, Six DA. Development and optimization of a higher throughput bacterial compound accumulation assay. Acs Infectious Diseases. PMID 30624052 DOI: 10.1021/Acsinfecdis.8B00299 |
0.338 |
|
| 2018 |
Nilsson I, Prathapam R, Grove K, Lapointe G, Six DA. The sialic acid transporter NanT is necessary and sufficient for uptake of 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) and its azido analog in Escherichia coli. Molecular Microbiology. PMID 30076772 DOI: 10.1111/Mmi.14098 |
0.361 |
|
| 2018 |
Spangler B, Dovala D, Sawyer WS, Thompson KV, Six DA, Reck F, Feng BY. Molecular probes for the determination of sub-cellular compound exposure profiles in Gram-negative bacteria. Acs Infectious Diseases. PMID 29846057 DOI: 10.1021/Acsinfecdis.8B00093 |
0.304 |
|
| 2018 |
Six DA, Krucker T, Leeds JA. Advances and challenges in bacterial compound accumulation assays for drug discovery. Current Opinion in Chemical Biology. 44: 9-15. PMID 29803973 DOI: 10.1016/J.Cbpa.2018.05.005 |
0.339 |
|
| 2018 |
Richie DL, Wang L, Chan H, De Pascale G, Six DA, Wei JR, Dean CR. A pathway-directed positive growth restoration assay to facilitate the discovery of lipid A and fatty acid biosynthesis inhibitors in Acinetobacter baumannii. Plos One. 13: e0193851. PMID 29505586 DOI: 10.1371/Journal.Pone.0193851 |
0.408 |
|
| 2017 |
Nilsson I, Grove K, Dovala D, Uehara T, Lapointe G, Six DA. Molecular characterization and verification of azido 3,8-dideoxy-D-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide. The Journal of Biological Chemistry. PMID 29018092 DOI: 10.1074/Jbc.M117.814962 |
0.383 |
|
| 2017 |
Tian H, Six DA, Krucker T, Leeds JA, Winograd N. Subcellular Chemical Imaging of Antibiotics in Single Bacteria Using C60-Secondary Ion Mass Spectrometry. Analytical Chemistry. 89: 5050-5057. PMID 28332827 DOI: 10.1021/Acs.Analchem.7B00466 |
0.312 |
|
| 2015 |
Bojkovic J, Richie DL, Six DA, Rath CM, Sawyer WS, Hu Q, Dean CR. Characterization of an Acinetobacter baumannii lptD Deletion Strain; Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis. Journal of Bacteriology. PMID 26668262 DOI: 10.1128/Jb.00639-15 |
0.446 |
|
| 2014 |
Six DA, Yuan Y, Leeds JA, Meredith TC. Deletion of the β-acetoacetyl synthase FabY in Pseudomonas aeruginosa induces hypoacylation of lipopolysaccharide and increases antimicrobial susceptibility. Antimicrobial Agents and Chemotherapy. 58: 153-61. PMID 24145528 DOI: 10.1128/Aac.01804-13 |
0.456 |
|
| 2013 |
Moon K, Six DA, Lee HJ, Raetz CR, Gottesman S. Complex transcriptional and post-transcriptional regulation of an enzyme for lipopolysaccharide modification. Molecular Microbiology. 89: 52-64. PMID 23659637 DOI: 10.1111/Mmi.12257 |
0.537 |
|
| 2013 |
Sun W, Six DA, Reynolds CM, Chung HS, Raetz CR, Curtiss R. Pathogenicity of Yersinia pestis synthesis of 1-dephosphorylated lipid A. Infection and Immunity. 81: 1172-85. PMID 23357387 DOI: 10.1128/Iai.01403-12 |
0.608 |
|
| 2012 |
Kong Q, Six DA, Liu Q, Gu L, Wang S, Alamuri P, Raetz CR, Curtiss R. Phosphate groups of lipid A are essential for Salmonella enterica serovar Typhimurium virulence and affect innate and adaptive immunity. Infection and Immunity. 80: 3215-24. PMID 22753374 DOI: 10.1128/Iai.00123-12 |
0.635 |
|
| 2012 |
Six DA, Lambert B, Raetz CR, Doerrler WT. Density gradient enrichment of Escherichia coli lpxL mutants. Biochimica Et Biophysica Acta. 1821: 989-93. PMID 22554681 DOI: 10.1016/J.Bbalip.2012.04.003 |
0.572 |
|
| 2011 |
Kong Q, Six DA, Liu Q, Gu L, Roland KL, Raetz CR, Curtiss R. Palmitoylation state impacts induction of innate and acquired immunity by the Salmonella enterica serovar typhimurium msbB mutant. Infection and Immunity. 79: 5027-38. PMID 21930761 DOI: 10.1128/Iai.05524-11 |
0.586 |
|
| 2011 |
Delucia AM, Six DA, Caughlan RE, Gee P, Hunt I, Lam JS, Dean CR. Lipopolysaccharide (LPS) inner-core phosphates are required for complete LPS synthesis and transport to the outer membrane in Pseudomonas aeruginosa PAO1. Mbio. 2. PMID 21810964 DOI: 10.1128/Mbio.00142-11 |
0.394 |
|
| 2011 |
Kong Q, Six DA, Roland KL, Liu Q, Gu L, Reynolds CM, Wang X, Raetz CR, Curtiss R. Salmonella synthesizing 1-dephosphorylated [corrected] lipopolysaccharide exhibits low endotoxic activity while retaining its immunogenicity. Journal of Immunology (Baltimore, Md. : 1950). 187: 412-23. PMID 21632711 DOI: 10.4049/Jimmunol.1100339 |
0.6 |
|
| 2011 |
Sun W, Six D, Kuang X, Roland KL, Raetz CR, Curtiss R. A live attenuated strain of Yersinia pestis KIM as a vaccine against plague. Vaccine. 29: 2986-98. PMID 21320544 DOI: 10.1016/J.Vaccine.2011.01.099 |
0.599 |
|
| 2010 |
Quehenberger O, Armando AM, Brown AH, Milne SB, Myers DS, Merrill AH, Bandyopadhyay S, Jones KN, Kelly S, Shaner RL, Sullards CM, Wang E, Murphy RC, Barkley RM, Leiker TJ, ... ... Six DA, et al. Lipidomics reveals a remarkable diversity of lipids in human plasma. Journal of Lipid Research. 51: 3299-305. PMID 20671299 DOI: 10.1194/Jlr.M009449 |
0.631 |
|
| 2009 |
Barb AW, Leavy TM, Robins LI, Guan Z, Six DA, Zhou P, Hangauer MJ, Bertozzi CR, Raetz CR. Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC. Biochemistry. 48: 3068-77. PMID 19256534 DOI: 10.1021/Bi900167Q |
0.704 |
|
| 2009 |
Karbarz MJ, Six DA, Raetz CR. Purification and characterization of the lipid A 1-phosphatase LpxE of Rhizobium leguminosarum. The Journal of Biological Chemistry. 284: 414-25. PMID 18984595 DOI: 10.1074/Jbc.M808390200 |
0.731 |
|
| 2009 |
Raetz CR, Guan Z, Ingram BO, Six DA, Song F, Wang X, Zhao J. Discovery of new biosynthetic pathways: the lipid A story. Journal of Lipid Research. 50: S103-8. PMID 18974037 DOI: 10.1194/Jlr.R800060-Jlr200 |
0.616 |
|
| 2009 |
Barb AW, Leavy TM, Robins LI, Guan Z, Six DA, Zhou P, Hangauer MJ, Bertozzi CR, Raetz C. Correction to uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC (Biochemistry (2009) 48, (3068) DOI: 10.1021/bi900167q) Biochemistry. 48: 7776. DOI: 10.1021/Bi9012066 |
0.675 |
|
| 2008 |
Six DA, Carty SM, Guan Z, Raetz CR. Purification and mutagenesis of LpxL, the lauroyltransferase of Escherichia coli lipid A biosynthesis. Biochemistry. 47: 8623-37. PMID 18656959 DOI: 10.1021/Bi800873N |
0.636 |
|
| 2007 |
Six DA, Barbayianni E, Loukas V, Constantinou-Kokotou V, Hadjipavlou-Litina D, Stephens D, Wong AC, Magrioti V, Moutevelis-Minakakis P, Baker SF, Dennis EA, Kokotos G. Structure-activity relationship of 2-oxoamide inhibition of group IVA cytosolic phospholipase A2 and group V secreted phospholipase A2. Journal of Medicinal Chemistry. 50: 4222-35. PMID 17672443 DOI: 10.1021/jm0613673 |
0.486 |
|
| 2006 |
Stephens D, Barbayianni E, Constantinou-Kokotou V, Peristeraki A, Six DA, Cooper J, Harkewicz R, Deems RA, Dennis EA, Kokotos G. Differential inhibition of group IVA and group VIA phospholipases A2 by 2-oxoamides. Journal of Medicinal Chemistry. 49: 2821-8. PMID 16640343 DOI: 10.1021/Jm050993H |
0.524 |
|
| 2005 |
Constantinou-Kokotou V, Peristeraki A, Kokotos CG, Six DA, Dennis EA. Synthesis and activity of 2-oxoamides containing long chain beta-amino acids. Journal of Peptide Science : An Official Publication of the European Peptide Society. 11: 431-5. PMID 15635664 DOI: 10.1002/Psc.628 |
0.493 |
|
| 2004 |
Kokotos G, Six DA, Loukas V, Smith T, Constantinou-Kokotou V, Hadjipavlou-Litina D, Kotsovolou S, Chiou A, Beltzner CC, Dennis EA. Inhibition of group IVA cytosolic phospholipase A2 by novel 2-oxoamides in vitro, in cells, and in vivo. Journal of Medicinal Chemistry. 47: 3615-28. PMID 15214789 DOI: 10.1021/Jm030485C |
0.548 |
|
| 2003 |
Phillips RM, Six DA, Dennis EA, Ghosh P. In vivo phospholipase activity of the Pseudomonas aeruginosa cytotoxin ExoU and protection of mammalian cells with phospholipase A2 inhibitors. The Journal of Biological Chemistry. 278: 41326-32. PMID 12915403 DOI: 10.1074/Jbc.M302472200 |
0.567 |
|
| 2003 |
Six DA, Dennis EA. Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity. The Journal of Biological Chemistry. 278: 23842-50. PMID 12672805 DOI: 10.1074/Jbc.M301386200 |
0.5 |
|
| 2002 |
Kokotos G, Kotsovolou S, Six DA, Constantinou-Kokotou V, Beltzner CC, Dennis EA. Novel 2-oxoamide inhibitors of human group IVA phospholipase A(2). Journal of Medicinal Chemistry. 45: 2891-3. PMID 12086476 DOI: 10.1021/Jm025538P |
0.526 |
|
| 2000 |
Six DA, Dennis EA. The expanding superfamily of phospholipase A(2) enzymes: classification and characterization. Biochimica Et Biophysica Acta. 1488: 1-19. PMID 11080672 DOI: 10.1016/S1388-1981(00)00105-0 |
0.533 |
|
| 1998 |
Mosior M, Six DA, Dennis EA. Group IV cytosolic phospholipase A2 binds with high affinity and specificity to phosphatidylinositol 4,5-bisphosphate resulting in dramatic increases in activity. The Journal of Biological Chemistry. 273: 2184-91. PMID 9442060 DOI: 10.1074/Jbc.273.4.2184 |
0.554 |
|
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