| Year |
Citation |
Score |
| 2020 |
Ciccone D, Lazari V, Linney I, Briggs M, Carreiro S, McElwee J, Waddell I, Hill C, Loh C, Tummino P, Collis A, Kaila N. 685 A highly selective and potent HPK1 inhibitor enhances immune cell activation and induces robust tumor growth inhibition in a murine syngeneic tumor model Journal For Immunotherapy of Cancer. 8: A724-A724. DOI: 10.1136/jitc-2020-sitc2020.0685 |
0.402 |
|
| 2020 |
Ciccone D, Lazari V, Linney I, Briggs M, Carreiro S, Waddell I, Hill C, Loh C, Tummino P, Collis A, Kaila N. A highly selective and potent HPK1 inhibitor enhances immune cell activation and induces robust tumor growth inhibition in a murine syngeneic tumor model European Journal of Cancer. 138: S20. DOI: 10.1016/s0959-8049(20)31118-7 |
0.305 |
|
| 2019 |
Csibi F, Ji N, Yang B, Yuan K, Mayo M, Rong H, Rusin S, Sharma K, Loh C, Li H, Townson S, Chen J, Kamadurai H, Walker D, Gollob J, et al. Small Molecule-Induced, Selective STAT3 Degradation Leads to Anti-Tumor Activity in STAT3-Dependent Heme Malignancies Blood. 134: 3803-3803. DOI: 10.1182/Blood-2019-128981 |
0.313 |
|
| 2019 |
Kelleher JF, Campbell V, Chen J, Gollob J, Ji N, Kamadurai H, Klaus C, Li H, Loh C, McDonald A, Rong H, Rusin S, Sharma K, Vigil D, Walker D, et al. Abstract LB-272: KYM-001, a first-in-class oral IRAK4 protein degrader, induces tumor regression in xenograft models of MYD88-mutant ABC DLBCL alone and in combination with BTK inhibition Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-272 |
0.383 |
|
| 2019 |
Csibi F, Ji N, Yang B, Yuan K, Mayo M, Rong H, Rusin S, Sharma K, Loh C, Li H, Townson S, Kamadurai H, Chen J, Walker D, Gollob J, et al. Abstract C054: Discovery of KYM-003, a potent and selective STAT3 degrader with antitumor activity in heme malignancies Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-C054 |
0.319 |
|
| 2018 |
Henry KL, Kellner D, Bajrami B, Anderson JE, Beyna M, Bhisetti G, Cameron T, Capacci AG, Bertolotti-Ciarlet A, Feng J, Gao B, Hopkins B, Jenkins T, Li K, May-Dracka T, ... ... Loh C, et al. CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling. Science Signaling. 11. PMID 30065029 DOI: 10.1126/Scisignal.Aam8216 |
0.404 |
|
| 2012 |
Yang H, Zhang W, Pan H, Feldser HG, Lainez E, Miller C, Leung S, Zhong Z, Zhao H, Sweitzer S, Considine T, Riera T, Suri V, White B, Ellis JL, ... ... Loh C, et al. SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity. Plos One. 7: e46364. PMID 23029496 DOI: 10.1371/Journal.Pone.0046364 |
0.399 |
|
| 2012 |
Pau E, Cheung YH, Loh C, Lajoie G, Wither JE. TLR tolerance reduces IFN-alpha production despite plasmacytoid dendritic cell expansion and anti-nuclear antibodies in NZB bicongenic mice. Plos One. 7: e36761. PMID 22574220 DOI: 10.1371/Journal.Pone.0036761 |
0.314 |
|
| 2010 |
NIWAYAMA S, LOH C, TURK BE, LIU JO, MIYACHI H, HASHIMOTO Y. ChemInform Abstract: Enhanced Potency of Perfluorinated Thalidomide Derivatives for Inhibition of LPS-Induced Tumor Necrosis Factor-α Production is Associated with a Change of Mechanism of Action. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199836166 |
0.601 |
|
| 1998 |
Niwayama S, Loh C, Turk BE, Liu JO, Miyachi H, Hashimoto Y. Enhanced potency of perfluorinated thalidomide derivatives for inhibition of LPS-induced tumor necrosis factor-α production is associated with a change of mechanism of action Bioorganic and Medicinal Chemistry Letters. 8: 1071-1076. PMID 9871710 DOI: 10.1016/S0960-894X(98)00171-1 |
0.588 |
|
| 1998 |
Sun L, Youn HD, Loh C, Stolow M, He W, Liu JO. Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes Immunity. 8: 703-711. PMID 9655484 DOI: 10.1016/S1074-7613(00)80575-0 |
0.47 |
|
| 1996 |
Loh C, Carew JA, Kim J, Hogan PG, Rao A. T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFAT1. Molecular and Cellular Biology. 16: 3945-54. PMID 8668212 DOI: 10.1128/MCB.16.7.3945 |
0.319 |
|
| 1996 |
Loh C, Shaw KTY, Carew J, Viola JPB, Luo C, Perrino BA, Rao A. Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity Journal of Biological Chemistry. 271: 10884-10891. PMID 8631904 DOI: 10.1074/Jbc.271.18.10884 |
0.316 |
|
| Show low-probability matches. |