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David W. Taylor - Publications

Affiliations: 
2016- Molecular Biosciences University of Texas at Austin, Austin, Texas, U.S.A. 
Website:
http://cryoem.cns.utexas.edu/about.html
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bravo JPK, Ramos DA, Ocampo RF, Ingram C, Taylor DW. Plasmid targeting and destruction by the DdmDE bacterial defence system. Nature. PMID 38740055 DOI: 10.1038/s41586-024-07515-9  0.32
2024 Schwartz EA, Bravo JPK, Ahsan M, Macias LA, McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS, Palermo G, Fineran PC, Fagerlund RD, Taylor DW. RNA targeting and cleavage by the type III-Dv CRISPR effector complex. Nature Communications. 15: 3324. PMID 38637512 DOI: 10.1038/s41467-024-47506-y  0.456
2023 Taylor D, Schwartz E, Bravo J, Ahsan M, Macias L, McCafferty C, Dangerfield T, Walker J, Brodbelt J, Palermo G, Fineran P, Fagerlund R. Type III CRISPR-Cas effectors act as protein-assisted ribozymes during RNA cleavage. Research Square. PMID 37163044 DOI: 10.21203/rs.3.rs-2837968/v1  0.423
2023 O'Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright JT, Taylor DW. Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Molecular Cell. PMID 36805026 DOI: 10.1016/j.molcel.2023.01.024  0.321
2023 Bravo JPK, Hallmark T, Naegle B, Beisel CL, Jackson RN, Taylor DW. RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature. 613: 582-587. PMID 36599980 DOI: 10.1038/s41586-022-05560-w  0.48
2022 Yelland JN, Bravo JPK, Black JJ, Taylor DW, Johnson AW. A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome. Nature Structural & Molecular Biology. PMID 36536102 DOI: 10.1038/s41594-022-00891-8  0.302
2022 Bravo JPK, Aparicio-Maldonado C, Nobrega FL, Brouns SJJ, Taylor DW. Structural basis for broad anti-phage immunity by DISARM. Nature Communications. 13: 2987. PMID 35624106 DOI: 10.1038/s41467-022-30673-1  0.327
2022 Schwartz EA, McBride TM, Bravo JPK, Wrapp D, Fineran PC, Fagerlund RD, Taylor DW. Structural rearrangements allow nucleic acid discrimination by type I-D Cascade. Nature Communications. 13: 2829. PMID 35595728 DOI: 10.1038/s41467-022-30402-8  0.342
2022 Bravo JPK, Liu MS, Hibshman GN, Dangerfield TL, Jung K, McCool RS, Johnson KA, Taylor DW. Structural basis for mismatch surveillance by CRISPR-Cas9. Nature. PMID 35236982 DOI: 10.1038/s41586-022-04470-1  0.391
2021 Steens JA, Zhu Y, Taylor DW, Bravo JPK, Prinsen SHP, Schoen CD, Keijser BJF, Ossendrijver M, Hofstra LM, Brouns SJJ, Shinkai A, van der Oost J, Staals RHJ. SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. Nature Communications. 12: 5033. PMID 34413302 DOI: 10.1038/s41467-021-25337-5  0.364
2021 Zhou Y, Bravo JPK, Taylor HN, Steens JA, Jackson RN, Staals RHJ, Taylor DW. Structure of a type IV CRISPR-Cas ribonucleoprotein complex. Iscience. 24: 102201. PMID 33733066 DOI: 10.1016/j.isci.2021.102201  0.385
2021 Bravo JPK, Dangerfield TL, Taylor DW, Johnson KA. Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication. Molecular Cell. PMID 33631104 DOI: 10.1016/j.molcel.2021.01.035  0.392
2020 O'Brien RE, Santos IC, Wrapp D, Bravo JPK, Schwartz EA, Brodbelt JS, Taylor DW. Structural basis for assembly of non-canonical small subunits into type I-C Cascade. Nature Communications. 11: 5931. PMID 33230133 DOI: 10.1038/s41467-020-19785-8  0.315
2020 Liu MS, Gong S, Yu HH, Jung K, Johnson KA, Taylor DW. Engineered CRISPR/Cas9 enzymes improve discrimination by slowing DNA cleavage to allow release of off-target DNA. Nature Communications. 11: 3576. PMID 32681021 DOI: 10.1038/S41467-020-17411-1  0.403
2020 McCafferty CL, Verbeke EJ, Marcotte EM, Taylor DW. Structural Biology in the Multi-Omics Era. Journal of Chemical Information and Modeling. PMID 32129623 DOI: 10.1021/Acs.Jcim.9B01164  0.333
2019 Verbeke EJ, Zhou Y, Horton AP, Mallam AL, Taylor DW, Marcotte EM. Separating distinct structures of multiple macromolecular assemblies from cryo-EM projections. Journal of Structural Biology. 107416. PMID 31726096 DOI: 10.1016/J.Jsb.2019.107416  0.334
2019 Taylor DW. The final cut: Cas9 editing. Nature Structural & Molecular Biology. PMID 31285603 DOI: 10.1038/S41594-019-0267-1  0.463
2019 Zhou Y, Musalgaonkar S, Johnson AW, Taylor DW. Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nature Communications. 10: 958. PMID 30814529 DOI: 10.1038/s41467-019-08880-0  0.447
2019 Liu MS, Gong S, Yu HH, Taylor DW, Johnson KA. Kinetic characterization of Cas9 enzymes. Methods in Enzymology. 616: 289-311. PMID 30691648 DOI: 10.1016/Bs.Mie.2018.10.022  0.502
2019 Simon AJ, Zhou Y, Ramasubramani V, Glaser J, Pothukuchy A, Gollihar J, Gerberich JC, Leggere JC, Morrow BR, Jung C, Glotzer SC, Taylor DW, Ellington AD. Supercharging enables organized assembly of synthetic biomolecules. Nature Chemistry. PMID 30643229 DOI: 10.2210/Pdb6Mdr/Pdb  0.315
2018 Yi X, Verbeke EJ, Chang Y, Dickinson DJ, Taylor DW. Electron microscopy snapshots of single particles from single cells. The Journal of Biological Chemistry. PMID 30541924 DOI: 10.1074/Jbc.Ra118.006686  0.333
2018 Verbeke EJ, Mallam AL, Drew K, Marcotte EM, Taylor DW. Classification of Single Particles from Human Cell Extract Reveals Distinct Structures. Cell Reports. 24: 259-268.e3. PMID 29972786 DOI: 10.1016/J.Celrep.2018.06.022  0.341
2018 Lee H, Zhou Y, Taylor DW, Sashital DG. Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays. Molecular Cell. PMID 29602742 DOI: 10.1016/J.Molcel.2018.03.003  0.69
2018 Gong S, Yu HH, Johnson KA, Taylor DW. DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity. Cell Reports. 22: 359-371. PMID 29320733 DOI: 10.1016/J.Celrep.2017.12.041  0.534
2018 Gong S, Yu HH, Johnson KA, Taylor DW. DNA Unwinding is the Primary Determinant of CRISPR-Cas9 Specificity Biophysical Journal. 114: 251a. DOI: 10.1016/J.Bpj.2017.11.1395  0.355
2016 Conley M, Emmott E, Orton R, Taylor D, Carneiro D, Murata K, Goodfellow I, Hansman G, Bhella D. Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures. The Journal of General Virology. PMID 27902397 DOI: 10.1099/Jgv.0.000658  0.355
2016 Hochstrasser ML, Taylor DW, Kornfeld JE, Nogales E, Doudna JA. DNA Targeting by a Minimal CRISPR RNA-Guided Cascade. Molecular Cell. 63: 840-51. PMID 27588603 DOI: 10.1016/J.Molcel.2016.07.027  0.776
2016 Yip WS, Shigematsu H, Taylor DW, Baserga SJ. Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs. Nucleic Acids Research. PMID 27342279 DOI: 10.1093/Nar/Gkw576  0.34
2016 Jiang F, Taylor DW, Chen JS, Kornfeld JE, Zhou K, Thompson AJ, Nogales E, Doudna JA. Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage. Science (New York, N.Y.). 351: 867-71. PMID 26841432 DOI: 10.1126/Science.Aad8282  0.74
2015 Tomko RJ, Taylor DW, Chen ZA, Wang HW, Rappsilber J, Hochstrasser M. A Single α Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly. Cell. 163: 432-44. PMID 26451487 DOI: 10.1016/J.Cell.2015.09.022  0.581
2015 Taylor DW, Zhu Y, Staals RH, Kornfeld JE, Shinkai A, van der Oost J, Nogales E, Doudna JA. Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning. Science (New York, N.Y.). 348: 581-5. PMID 25837515 DOI: 10.1126/Science.Aaa4535  0.773
2015 Wright AV, Sternberg SH, Taylor DW, Staahl BT, Bardales JA, Kornfeld JE, Doudna JA. Rational design of a split-Cas9 enzyme complex. Proceedings of the National Academy of Sciences of the United States of America. 112: 2984-9. PMID 25713377 DOI: 10.1073/Pnas.1501698112  0.779
2014 Staals RH, Zhu Y, Taylor DW, Kornfeld JE, Sharma K, Barendregt A, Koehorst JJ, Vlot M, Neupane N, Varossieau K, Sakamoto K, Suzuki T, Dohmae N, Yokoyama S, Schaap PJ, et al. RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus. Molecular Cell. 56: 518-30. PMID 25457165 DOI: 10.1016/J.Molcel.2014.10.005  0.727
2014 Hochstrasser ML, Taylor DW, Bhat P, Guegler CK, Sternberg SH, Nogales E, Doudna JA. CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference. Proceedings of the National Academy of Sciences of the United States of America. 111: 6618-23. PMID 24748111 DOI: 10.1073/Pnas.1405079111  0.795
2014 Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA. Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science (New York, N.Y.). 343: 1247997. PMID 24505130 DOI: 10.1126/Science.1247997  0.801
2014 Yip WSV, Shigematsu H, Taylor DW, Wang HW, Baserga SJ. Cryo-electron microscopic study of the enzymatic mechanism of the RNA 2'-O-methyltransferase Box C\D sRNP Microscopy and Microanalysis. 20: 1284-1285. DOI: 10.1017/S1431927614008150  0.549
2014 Hochstrasser ML, Taylor DW, Bhat P, Guegler CK, Doudna JA. Target Recognition and Degradation by an Adaptive Bacterial Immune System Biophysical Journal. 106: 695a. DOI: 10.1016/J.Bpj.2013.11.3847  0.624
2013 Staals RH, Agari Y, Maki-Yonekura S, Zhu Y, Taylor DW, van Duijn E, Barendregt A, Vlot M, Koehorst JJ, Sakamoto K, Masuda A, Dohmae N, Schaap PJ, Doudna JA, Heck AJ, et al. Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilus. Molecular Cell. 52: 135-45. PMID 24119403 DOI: 10.1016/J.Molcel.2013.09.013  0.599
2013 Wolin SL, Belair C, Boccitto M, Chen X, Sim S, Taylor DW, Wang HW. Non-coding Y RNAs as tethers and gates: Insights from bacteria. Rna Biology. 10: 1602-8. PMID 24036917 DOI: 10.4161/Rna.26166  0.674
2013 Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW. Substrate-specific structural rearrangements of human Dicer. Nature Structural & Molecular Biology. 20: 662-70. PMID 23624860 DOI: 10.1038/Nsmb.2564  0.775
2013 Chen X, Taylor DW, Fowler CC, Galan JE, Wang HW, Wolin SL. An RNA degradation machine sculpted by Ro autoantigen and noncoding RNA. Cell. 153: 166-77. PMID 23540697 DOI: 10.1016/J.Cell.2013.02.037  0.684
2013 Yip W, Shigematsu H, Taylor D, Wang H, Baserga S. Structural Elucidation of Archaeal Box C/D sRNP by Cryo-Electron Microscopy Microscopy and Microanalysis. 19: 126-127. DOI: 10.1017/S1431927613002626  0.539
2012 Bower-Phipps KR, Taylor DW, Wang HW, Baserga SJ. The box C/D sRNP dimeric architecture is conserved across domain Archaea. Rna (New York, N.Y.). 18: 1527-40. PMID 22753779 DOI: 10.1261/Rna.033134.112  0.611
2012 Hansman GS, Taylor DW, McLellan JS, Smith TJ, Georgiev I, Tame JR, Park SY, Yamazaki M, Gondaira F, Miki M, Katayama K, Murata K, Kwong PD. Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle. Journal of Virology. 86: 3635-46. PMID 22278249 DOI: 10.1128/Jvi.06868-11  0.315
2009 Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, Doudna JA, Nogales E. Structural insights into RNA processing by the human RISC-loading complex. Nature Structural & Molecular Biology. 16: 1148-53. PMID 19820710 DOI: 10.1038/Nsmb.1673  0.754
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