Year |
Citation |
Score |
2024 |
Childers MC, Geeves MA, Regnier M. An atomistic model of myosin interacting heads motif dynamics and their modification by 2'-deoxy-ADP. Biorxiv : the Preprint Server For Biology. PMID 38895221 DOI: 10.1101/2024.06.06.597809 |
0.345 |
|
2024 |
Rynkiewicz MJ, Childers MC, Karpicheva OE, Regnier M, Geeves MA, Lehman W. Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin. The Journal of General Physiology. 156. PMID 38607351 DOI: 10.1085/jgp.202413538 |
0.357 |
|
2023 |
Kao K, Geeves MA. Protocols for Myosin and Actin-Myosin Assays Using Rapid, Stopped-Flow Kinetics. Methods in Molecular Biology (Clifton, N.J.). 2735: 191-211. PMID 38038850 DOI: 10.1007/978-1-0716-3527-8_11 |
0.333 |
|
2022 |
Yampolskaya DS, Kopylova GV, Shchepkin DV, Nabiev SR, Nikitina LV, Walklate J, Ziganshin RH, Bershitsky SY, Geeves MA, Matyushenko AM, Levitsky DI. Pseudo-phosphorylation of essential light chains affects the functioning of skeletal muscle myosin. Biophysical Chemistry. 292: 106936. PMID 36436358 DOI: 10.1016/j.bpc.2022.106936 |
0.336 |
|
2022 |
Pilagov M, Heling LWHJ, Walklate J, Geeves MA, Kad NM. Single-molecule imaging reveals how mavacamten and PKA modulate ATP turnover in skeletal muscle myofibrils. The Journal of General Physiology. 155. PMID 36394553 DOI: 10.1085/jgp.202213087 |
0.309 |
|
2022 |
Lee LA, Barrick SK, Meller A, Walklate J, Lotthammer JM, Tay JW, Stump WT, Bowman G, Geeves MA, Greenberg MJ, Leinwand LA. Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles. The Journal of Biological Chemistry. 102657. PMID 36334627 DOI: 10.1016/j.jbc.2022.102657 |
0.304 |
|
2022 |
Walklate J, Kao K, Regnier M, Geeves MA. Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle. The Journal of Biological Chemistry. 298: 101640. PMID 35090895 DOI: 10.1016/j.jbc.2022.101640 |
0.317 |
|
2021 |
Mijailovich SM, Prodanovic M, Poggesi C, Geeves MA, Regnier M. Multiscale modeling of twitch contractions in cardiac trabeculae. The Journal of General Physiology. 153. PMID 33512405 DOI: 10.1085/jgp.202012604 |
0.301 |
|
2020 |
Childers MC, Geeves M, Daggett V, Regnier M. Modulation of post-powerstroke dynamics in myosin II by 2'-deoxy-ADP. Archives of Biochemistry and Biophysics. 699: 108733. PMID 33388313 DOI: 10.1016/j.abb.2020.108733 |
0.34 |
|
2020 |
Bloemink MJ, Hsu KH, Geeves MA, Bernstein SI. Alternative N-terminal regions of myosin heavy chain II regulate communication of the purine binding loop with the essential light chain. The Journal of Biological Chemistry. PMID 32817166 DOI: 10.1074/Jbc.Ra120.014684 |
0.434 |
|
2020 |
Doran MH, Pavadai E, Rynkiewicz MJ, Walklate J, Bullitt E, Moore JR, Regnier M, Geeves MA, Lehman W. Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. Biophysical Journal. PMID 32730789 DOI: 10.1016/J.Bpj.2020.07.006 |
0.473 |
|
2020 |
Heling LWHJ, Geeves MA, Kad NM. MyBP-C: one protein to govern them all Journal of Muscle Research and Cell Motility. 41: 91-101. PMID 31960266 DOI: 10.1007/S10974-019-09567-1 |
0.368 |
|
2019 |
Hellerschmied D, Lehner A, Franicevic N, Arnese R, Johnson C, Vogel A, Meinhart A, Kurzbauer R, Deszcz L, Gazda L, Geeves M, Clausen T. Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin. Nature Communications. 10: 4781. PMID 31636255 DOI: 10.1038/S41467-019-12667-8 |
0.464 |
|
2019 |
Vera CD, Johnson CA, Walklate J, Adhikari A, Svicevic M, Mijailovich SM, Combs AC, Langer SJ, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties. The Journal of Biological Chemistry. PMID 31582565 DOI: 10.1074/Jbc.Ra119.010563 |
0.344 |
|
2019 |
Geeves MA, Lehrer SS, Lehman W. The mechanism of thin filament regulation: Models in conflict? The Journal of General Physiology. PMID 31570503 DOI: 10.1085/Jgp.201912446 |
0.395 |
|
2019 |
Baker K, Gyamfi IA, Mashanov GI, Molloy JE, Geeves MA, Mulvihill DP. TORC2-Gad8 dependent myosin phosphorylation modulates regulation by calcium. Elife. 8. PMID 31566560 DOI: 10.7554/Elife.51150 |
0.339 |
|
2019 |
Johnson CA, Walklate J, Svicevic M, Mijailovich SM, Vera CD, Karabina A, Leinwand LA, Geeves MA. The ATPase cycle of human muscle myosin II Isoforms: adaptation of a single mechanochemical cycle for different physiological roles. The Journal of Biological Chemistry. PMID 31387944 DOI: 10.1074/Jbc.Ra119.009825 |
0.406 |
|
2019 |
Walklate J, Ujfalusi Z, Behrens V, King EJ, Geeves MA. A micro-volume adaptation of a stopped-flow system; use with μg quantities of muscle proteins. Analytical Biochemistry. PMID 31201789 DOI: 10.1016/J.Ab.2019.06.009 |
0.339 |
|
2019 |
Mijailovich SM, Stojanovic B, Nedic D, Svicevic M, Geeves MA, Irving TC, Granzier HL. Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity. The Journal of General Physiology. PMID 30948421 DOI: 10.1085/Jgp.201812165 |
0.448 |
|
2019 |
Mitrou GI, Sakkas GK, Poulianiti KP, Karioti A, Tepetes K, Christodoulidis G, Giakas G, Stefanidis I, Geeves MA, Koutedakis Y, Karatzaferi C. Evidence of functional deficits at the single muscle fiber level in experimentally-induced renal insufficiency. Journal of Biomechanics. 82: 259-265. PMID 30447801 DOI: 10.1016/J.Jbiomech.2018.10.035 |
0.317 |
|
2019 |
Mijailovich SM, Prodanovic M, Vasovic L, Stojanovic B, Maric M, Prodanovic D, Powers JD, Davis J, Geeves MA, Regnier M. Modulation of Calcium Sensitivity and Twitch Contractions in Cardiac Muscle with Troponin-C Mutations: Simulations and Experiments Biophysical Journal. 116: 116a. DOI: 10.1016/J.Bpj.2018.11.654 |
0.333 |
|
2018 |
Behrens VA, Walter WJ, Peters C, Wang T, Brenner B, Geeves MA, Scholz T, Steffen W. Mg -free ATP Regulates the Processivity of Native Cytoplasmic Dynein. Febs Letters. PMID 30575960 DOI: 10.1002/1873-3468.13319 |
0.343 |
|
2018 |
Ujfalusi Z, Vera CD, Mijailovich SM, Svicevic M, Yu EC, Kawana M, Ruppel K, Spudich JA, Geeves MA, Leinwand LA. Dilated cardiomyopathy myosin mutants have reduced force-generating capacity. The Journal of Biological Chemistry. PMID 29666183 DOI: 10.1074/Jbc.Ra118.001938 |
0.398 |
|
2018 |
Mijailovich SM, Nedic D, Stojanovic B, Powers JD, Davis J, Geeves MA, Regnier M. Influence of cTn Ca2+ Binding Properties and Cooperative Mechanisms on Cardiac Muscle Contractile Dynamics Biophysical Journal. 114: 500a. DOI: 10.1016/J.Bpj.2017.11.2737 |
0.367 |
|
2017 |
Johnson CA, Brooker HR, Gyamfi I, O'Brien J, Ashley B, Brazier JE, Dean A, Embling J, Grimsey E, Tomlinson AC, Wilson EG, Geeves MA, Mulvihill DP. Temperature sensitive point mutations in fission yeast tropomyosin have long range effects on protein stability that destabilise the actin-tropomyosin copolymer in vitro and in vivo. Biochemical and Biophysical Research Communications. PMID 29080743 DOI: 10.1016/J.Bbrc.2017.10.109 |
0.402 |
|
2017 |
Karatzaferi C, Adamek N, Geeves MA. Modulators of actin-myosin dissociation: basis for muscle type functional differences during fatigue. American Journal of Physiology. Cell Physiology. ajpcell.00023.2017. PMID 28931538 DOI: 10.1152/Ajpcell.00023.2017 |
0.396 |
|
2017 |
Mijailovich SM, Nedic D, Svicevic M, Stojanovic B, Walklate J, Ujfalusi Z, Geeves MA. Modeling the Actin.myosin ATPase Cross-Bridge Cycle for Skeletal and Cardiac Muscle Myosin Isoforms. Biophysical Journal. 112: 984-996. PMID 28297657 DOI: 10.1016/J.Bpj.2017.01.021 |
0.443 |
|
2017 |
Mijailovich SM, Nedic D, Stojanovic B, Irving TC, Geeves MA. Modulation of Fast Transients by Compliance of Crossbridges and Myofilaments Biophysical Journal. 112: 115a. DOI: 10.1016/J.Bpj.2016.11.649 |
0.383 |
|
2017 |
Inchingolo AV, Mihailescu MD, Dai H, Geeves MA, Kad NM. Single Molecule Imaging Reveals the Mechanism Ofactin.Tn.Tm Activation and Deactivation Biophysical Journal. 112: 10a. DOI: 10.1016/J.Bpj.2016.11.085 |
0.439 |
|
2016 |
Mijailovich SM, Kayser-Herold O, Stojanovic B, Nedic D, Irving TC, Geeves MA. Three-dimensional stochastic model of actin-myosin binding in the sarcomere lattice. The Journal of General Physiology. PMID 27864330 DOI: 10.1085/Jgp.201611608 |
0.45 |
|
2016 |
Brooker HR, Geeves MA, Mulvihill DP. Analysis of biophysical and functional consequences of tropomyosin-fluorescent protein fusions. Febs Letters. 590: 3111-21. PMID 27501521 DOI: 10.1002/1873-3468.12346 |
0.339 |
|
2016 |
Walklate J, Vera C, Bloemink MJ, Geeves MA, Leinwand L. The Most Prevalent Freeman-Sheldon Syndrome Mutations in the Embryonic Myosin Motor Share Functional Defects. The Journal of Biological Chemistry. 291: 10318-31. PMID 26945064 DOI: 10.1074/Jbc.M115.707489 |
0.407 |
|
2016 |
Walklate J, Ujfalusi Z, Geeves MA. Myosin isoforms and the mechanochemical cross-bridge cycle. The Journal of Experimental Biology. 219: 168-74. PMID 26792327 DOI: 10.1242/Jeb.124594 |
0.465 |
|
2016 |
Bloemink MJ, Melkani GC, Bernstein SI, Geeves MA. The Relay/Converter Interface Influences Hydrolysis of ATP by Skeletal Muscle Myosin II. The Journal of Biological Chemistry. 291: 1763-73. PMID 26586917 DOI: 10.1074/Jbc.M115.688002 |
0.429 |
|
2016 |
Vera Velazquez CD, Walklate J, Geeves MA, Leinwand LA. β-MYHC Mutations Linked to Early-Onset HCM and DCM Show Differences in Pre-Steady and Steady State Kinetic Parameters Biophysical Journal. 110: 614a. DOI: 10.1016/J.Bpj.2015.11.3295 |
0.356 |
|
2016 |
Mijailovich SM, Nedic D, Svicevic M, Stojanovic B, Regnier M, Geeves MA. Dynamic Transient Responses of Muscle Fibers with a Heterogeneous Populations of Isoforms and Mutation Biophysical Journal. 110: 299a. DOI: 10.1016/J.Bpj.2015.11.1611 |
0.412 |
|
2016 |
Mijailovich SM, Stojanovic B, Nedic D, Geeves MA. Myosin Binding to Actin in the 3D Sarcomere Lattice Biophysical Journal. 110: 299a. DOI: 10.1016/J.Bpj.2015.11.1610 |
0.45 |
|
2015 |
Nag S, Sommese RF, Ujfalusi Z, Combs A, Langer S, Sutton S, Leinwand LA, Geeves MA, Ruppel KM, Spudich JA. Contractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function. Science Advances. 1: e1500511. PMID 26601291 DOI: 10.1126/Sciadv.1500511 |
0.385 |
|
2015 |
Lehman W, Medlock G, Li XE, Suphamungmee W, Tu AY, Schmidtmann A, Ujfalusi Z, Fischer S, Moore JR, Geeves MA, Regnier M. Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain. Archives of Biochemistry and Biophysics. 571: 10-5. PMID 25726728 DOI: 10.1016/J.Abb.2015.02.026 |
0.425 |
|
2015 |
Desai R, Geeves MA, Kad NM. Using fluorescent myosin to directly visualize cooperative activation of thin filaments. The Journal of Biological Chemistry. 290: 1915-25. PMID 25429108 DOI: 10.1074/Jbc.M114.609743 |
0.447 |
|
2015 |
Geeves MA, Hitchcock-DeGregori SE, Gunning PW. A systematic nomenclature for mammalian tropomyosin isoforms. Journal of Muscle Research and Cell Motility. 36: 147-53. PMID 25369766 DOI: 10.1007/S10974-014-9389-6 |
0.392 |
|
2015 |
Mijailovich SM, Nedic D, Svicevic M, Stojanovic B, Geeves M. Modelling the Calcium Dependent Actin-Myosin ATP-ase Cycle in Solution Biophysical Journal. 108: 594a. DOI: 10.1016/J.Bpj.2014.11.3234 |
0.406 |
|
2015 |
Mijailovich SM, Stojanovic B, Nedic D, Geeves MA. Activation and Relaxation Kinetics in Skeletal and Cardiac Muscles Biophysical Journal. 108: 337a-338a. DOI: 10.1016/J.Bpj.2014.11.1843 |
0.419 |
|
2015 |
Velazquez CV, Walklate J, Deacon J, Geeves MA, Leinwand LA. Functional Analysis of Freeman-Sheldon Syndrome Causing Mutations on Embryonic Myosin Biophysical Journal. 108: 304a. DOI: 10.1016/J.Bpj.2014.11.1652 |
0.454 |
|
2015 |
Nedic D, Svicevic M, Stojanovic B, Geeves MA, Irving T, Gilbert RJ, Mijailovich SM. Effect of Mutations in cMyBP-C on Sarcomere Mechanical Function Biophysical Journal. 108: 200a. DOI: 10.1016/J.Bpj.2014.11.1108 |
0.407 |
|
2014 |
Geeves MA, Lehrer SS. Cross-talk, cross-bridges, and calcium activation of cardiac contraction. Biophysical Journal. 107: 543-545. PMID 25099792 DOI: 10.1016/J.Bpj.2014.06.019 |
0.387 |
|
2014 |
Adamek N, Geeves MA. Use of pyrene-labelled actin to probe actin-myosin interactions: kinetic and equilibrium studies. Experientia Supplementum (2012). 105: 87-104. PMID 25095992 DOI: 10.1007/978-3-0348-0856-9_5 |
0.416 |
|
2014 |
Lawrence AD, Taylor SL, Scott A, Rowe ML, Johnson CM, Rigby SE, Geeves MA, Pickersgill RW, Howard MJ, Warren MJ. FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR). Bioscience Reports. 34. PMID 24909839 DOI: 10.1042/Bsr20140060 |
0.312 |
|
2014 |
Lehrer SS, Geeves MA. The myosin-activated thin filament regulatory state, M- -open: A link to hypertrophic cardiomyopathy (HCM) Journal of Muscle Research and Cell Motility. 35: 153-160. PMID 24740688 DOI: 10.1007/S10974-014-9383-Z |
0.387 |
|
2014 |
Bloemink M, Deacon J, Langer S, Vera C, Combs A, Leinwand L, Geeves MA. The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac β-myosin. The Journal of Biological Chemistry. 289: 5158-67. PMID 24344137 DOI: 10.1074/Jbc.M113.511204 |
0.414 |
|
2014 |
Mijailovich SM, Nedic D, Stojanovic B, Geeves MA. Effect of Nonlinear Crossbridge Elasticity on Kinetics of Sarcomeric Contraction Biophysical Journal. 106: 158a. DOI: 10.1016/J.Bpj.2013.11.906 |
0.409 |
|
2014 |
Svicevic M, Mijailovich SM, Janco M, Geeves MA. Myosin Binding to Human Cardiac Thin Filaments Containing Tropomyosin Carrying DCM & HCM Mutations; Fitting of Complex Binding Transients Biophysical Journal. 106: 769a. DOI: 10.1016/J.Bpj.2013.11.4224 |
0.381 |
|
2014 |
Bloemink M, Deacon J, Langer S, Vera C, Combs A, Leinwand L, Geeves MA. The Hcm Mutation R453C in the Human Beta Myosin Motor Domain Alters the ATP-Binding and Hydrolysis Steps Biophysical Journal. 106: 561a. DOI: 10.1016/J.Bpj.2013.11.3119 |
0.456 |
|
2014 |
Medlock G, Suphamungmee W, Tu A, Li X(, Regnier M, Geeves MA, Lehman W. Effects of Phosphomimetic Mutations on the Persistence Length and Thin Filament Binding Properties of α and β-Tropomyosin Biophysical Journal. 106: 252a. DOI: 10.1016/J.Bpj.2013.11.1485 |
0.42 |
|
2013 |
Bloemink MJ, Deacon JC, Resnicow DI, Leinwand LA, Geeves MA. The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms. The Journal of Biological Chemistry. 288: 27469-79. PMID 23908353 DOI: 10.1074/Jbc.M113.488130 |
0.415 |
|
2013 |
Janco M, Suphamungmee W, Li X, Lehman W, Lehrer SS, Geeves MA. Polymorphism in tropomyosin structure and function. Journal of Muscle Research and Cell Motility. 34: 177-87. PMID 23832280 DOI: 10.1007/S10974-013-9353-X |
0.346 |
|
2013 |
Mijailovich SM, Stojanovic B, Nedic D, Svicevic M, Gilbert RJ, Geeves MA, Irving T. Modulation of Crossbridge Cycling Kinetics and Length Dependent Calcium Sensitivity by Titin and Nebulin Biophysical Journal. 104: 310a. DOI: 10.1016/J.Bpj.2012.11.1723 |
0.422 |
|
2013 |
Nowakowski SG, Adamek N, Geeves MA, Gay E, Kolwicz SC, Murry CE, Daggett V, Regnier M. 2-deoxy-ATP Alters Myosin Structure to Enhance Cross-Bridge Cycling and Improve Cardiac Function Biophysical Journal. 104: 17a. DOI: 10.1016/J.Bpj.2012.11.125 |
0.466 |
|
2012 |
Janco M, Kalyva A, Scellini B, Piroddi N, Tesi C, Poggesi C, Geeves MA. α-Tropomyosin with a D175N or E180G mutation in only one chain differs from tropomyosin with mutations in both chains. Biochemistry. 51: 9880-90. PMID 23170982 DOI: 10.1021/Bi301323N |
0.341 |
|
2012 |
Mijailovich SM, Kayser-Herold O, Li X, Griffiths H, Geeves MA. Cooperative regulation of myosin-S1 binding to actin filaments by a continuous flexible Tm-Tn chain. European Biophysics Journal : Ebj. 41: 1015-32. PMID 23052974 DOI: 10.1007/S00249-012-0859-8 |
0.452 |
|
2012 |
Geeves MA, Ranatunga KW. Tuning the calcium sensitivity of cardiac muscle. Biophysical Journal. 103: 849-50. PMID 23009833 DOI: 10.1016/J.Bpj.2012.07.039 |
0.45 |
|
2012 |
Deacon JC, Bloemink MJ, Rezavandi H, Geeves MA, Leinwand LA. Erratum to: Identification of functional differences between recombinant human α and β cardiac myosin motors. Cellular and Molecular Life Sciences : Cmls. 69: 4239-55. PMID 23001010 DOI: 10.1007/S00018-012-1111-5 |
0.327 |
|
2012 |
Kalyva A, Schmidtmann A, Geeves MA. In vitro formation and characterization of the skeletal muscle α·β tropomyosin heterodimers. Biochemistry. 51: 6388-99. PMID 22812662 DOI: 10.1021/Bi300340R |
0.371 |
|
2012 |
Li XE, Suphamungmee W, Janco M, Geeves MA, Marston SB, Fischer S, Lehman W. The flexibility of two tropomyosin mutants, D175N and E180G, that cause hypertrophic cardiomyopathy Biochemical and Biophysical Research Communications. 424: 493-496. PMID 22789852 DOI: 10.1016/J.Bbrc.2012.06.141 |
0.459 |
|
2012 |
Canepari M, Maffei M, Longa E, Geeves M, Bottinelli R. Actomyosin kinetics of pure fast and slow rat myosin isoforms studied by in vitro motility assay approach. Experimental Physiology. 97: 873-81. PMID 22467761 DOI: 10.1113/Expphysiol.2012.064576 |
0.341 |
|
2012 |
Deacon JC, Bloemink MJ, Rezavandi H, Geeves MA, Leinwand LA. Identification of functional differences between recombinant human α and β cardiac myosin motors. Cellular and Molecular Life Sciences : Cmls. 69: 2261-77. PMID 22349210 DOI: 10.1007/S00018-012-0927-3 |
0.327 |
|
2012 |
Mijailovich SM, Li X, Griffiths RH, Geeves MA. The Hill model for binding myosin S1 to regulated actin is not equivalent to the McKillop-Geeves model. Journal of Molecular Biology. 417: 112-28. PMID 22306466 DOI: 10.1016/J.Jmb.2012.01.011 |
0.373 |
|
2012 |
Bloemink MJ, Melkani GC, Geeves MA, Bernstein SI. Kinetic Characterization of Converter and Relay Loop Domain Interaction in Drosophila Myosin Sub-Fragment 1 Biophysical Journal. 102: 149a. DOI: 10.1016/J.Bpj.2011.11.812 |
0.414 |
|
2012 |
Alexander CJ, Mulvihill DP, Geeves MA. Interactions of Calmodulin and the IQ Motifs of a Type I Myosin in Fission Yeast Biophysical Journal. 102: 566a. DOI: 10.1016/J.Bpj.2011.11.3086 |
0.441 |
|
2011 |
Bloemink MJ, Geeves MA. Shaking the myosin family tree: biochemical kinetics defines four types of myosin motor. Seminars in Cell & Developmental Biology. 22: 961-7. PMID 22001381 DOI: 10.1016/J.Semcdb.2011.09.015 |
0.394 |
|
2011 |
Korte FS, Dai J, Buckley K, Feest ER, Adamek N, Geeves MA, Murry CE, Regnier M. Upregulation of cardiomyocyte ribonucleotide reductase increases intracellular 2 deoxy-ATP, contractility, and relaxation. Journal of Molecular and Cellular Cardiology. 51: 894-901. PMID 21925507 DOI: 10.1016/J.Yjmcc.2011.08.026 |
0.367 |
|
2011 |
Preller M, Bauer S, Adamek N, Fujita-Becker S, Fedorov R, Geeves MA, Manstein DJ. Structural basis for the allosteric interference of myosin function by reactive thiol region mutations G680A and G680V. The Journal of Biological Chemistry. 286: 35051-60. PMID 21841195 DOI: 10.1074/Jbc.M111.265298 |
0.337 |
|
2011 |
Rayes RF, Kálai T, Hideg K, Geeves MA, Fajer PG. Dynamics of tropomyosin in muscle fibers as monitored by saturation transfer EPR of bi-functional probe. Plos One. 6: e21277. PMID 21701580 DOI: 10.1371/Journal.Pone.0021277 |
0.342 |
|
2011 |
Bloemink MJ, Melkani GC, Dambacher CM, Bernstein SI, Geeves MA. Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities. The Journal of Biological Chemistry. 286: 28435-43. PMID 21680742 DOI: 10.1074/Jbc.M111.258228 |
0.414 |
|
2011 |
Geeves M, Griffiths H, Mijailovich S, Smith D. Cooperative [Ca²+]-dependent regulation of the rate of myosin binding to actin: solution data and the tropomyosin chain model. Biophysical Journal. 100: 2679-87. PMID 21641313 DOI: 10.1016/J.Bpj.2011.04.020 |
0.464 |
|
2011 |
Adamek N, Geeves MA, Coluccio LM. Myo1c mutations associated with hearing loss cause defects in the interaction with nucleotide and actin. Cellular and Molecular Life Sciences : Cmls. 68: 139-50. PMID 20640478 DOI: 10.1007/S00018-010-0448-X |
0.409 |
|
2011 |
Rezavandi H, Geeves MA. Kinetics of Mouse Alpha-Myosin S1 a Fast Myosin Biophysical Journal. 100: 454a. DOI: 10.1016/J.Bpj.2010.12.2677 |
0.423 |
|
2011 |
Deacon JC, Bloemink MJ, Geeves MA, Leinwand LA. Kinetic Analysis of Human α and β Cardiac Myosin Motor Domains Biophysical Journal. 100: 369a-370a. DOI: 10.1016/J.Bpj.2010.12.2204 |
0.321 |
|
2010 |
Adamek N, Lieto-Trivedi A, Geeves MA, Coluccio LM. Modification of loop 1 affects the nucleotide binding properties of Myo1c, the adaptation motor in the inner ear. Biochemistry. 49: 958-71. PMID 20039646 DOI: 10.1016/J.Bpj.2008.12.3864 |
0.45 |
|
2010 |
Rayes RF, Geeves MA, Fajer PG. EPR as a Tool to Study the Dynamic of Tropomyosin in the Muscle Fiber - Use of a Bifunctional Spin Label Biophysical Journal. 98: 351a. DOI: 10.1016/J.Bpj.2009.12.1898 |
0.396 |
|
2009 |
Albet-Torres N, Bloemink MJ, Barman T, Candau R, Frölander K, Geeves MA, Golker K, Herrmann C, Lionne C, Piperio C, Schmitz S, Veigel C, Månsson A. Drug effect unveils inter-head cooperativity and strain-dependent ADP release in fast skeletal actomyosin. The Journal of Biological Chemistry. 284: 22926-37. PMID 19520847 DOI: 10.1074/Jbc.M109.019232 |
0.408 |
|
2009 |
Bloemink MJ, Dambacher CM, Knowles AF, Melkani GC, Geeves MA, Bernstein SI. Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head. Journal of Molecular Biology. 389: 707-21. PMID 19393244 DOI: 10.1016/J.Jmb.2009.04.036 |
0.384 |
|
2009 |
Rayes RF, Coulton AT, Geeves MA, Fajer PG. Dynamics of Bi-Functional Labeled Tropomyosin in Muscle Ghost Fiber Monitored by Saturation Transfer EPR Biophysical Journal. 96: 376a. DOI: 10.1016/J.Bpj.2008.12.2821 |
0.385 |
|
2009 |
Bloemink MJ, Dambacher CM, Melkani G, Geeves M, Bernstein SI. Kinetics Of Two Single Point Mutants Of Drosophila Myosin S1 Biophysical Journal. 96: 496a-497a. DOI: 10.1016/J.Bpj.2008.12.2563 |
0.378 |
|
2009 |
Albet-Torres N, Bloemink MJ, Barman T, Candau R, Geeves MA, Golker K, Herrmann C, Lionne C, Piperio C, Schmitz S, Veigel C, Mansson A. Drug Effects and Mechanism Underlying the Force-velocity Relationship of Skeletal Muscle Biophysical Journal. 96: 201a. DOI: 10.1016/J.Bpj.2008.12.1079 |
0.397 |
|
2008 |
Bernstein SI, Geeves MA. The XXXVII European muscle conference: Oxford September 2008. Journal of Muscle Research and Cell Motility. 29: 253-6. PMID 19034677 DOI: 10.1007/S10974-008-9151-Z |
0.336 |
|
2008 |
Pearson DS, Swartz DR, Geeves MA. Fast pressure jumps can perturb calcium and magnesium binding to troponin C F29W. Biochemistry. 47: 12146-58. PMID 18942859 DOI: 10.1021/Bi801150W |
0.372 |
|
2008 |
Smith DA, Geeves MA, Sleep J, Mijailovich SM. Towards a unified theory of muscle contraction. I: foundations. Annals of Biomedical Engineering. 36: 1624-40. PMID 18642081 DOI: 10.1007/S10439-008-9536-6 |
0.434 |
|
2008 |
Meshcheryakov V, Nitanai Y, Maytum R, Geeves MA, Maeda Y. Crystallization and preliminary X-ray crystallographic analysis of full-length yeast tropomyosin 2 from Saccharomyces cerevisiae. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 528-30. PMID 18540067 DOI: 10.1107/S1744309108013110 |
0.312 |
|
2008 |
Adamek N, Coluccio LM, Geeves MA. Calcium sensitivity of the cross-bridge cycle of Myo1c, the adaptation motor in the inner ear. Proceedings of the National Academy of Sciences of the United States of America. 105: 5710-5. PMID 18391215 DOI: 10.1073/Pnas.0710520105 |
0.359 |
|
2008 |
Tsiavaliaris G, Fujita-Becker S, Dürrwang U, Diensthuber RP, Geeves MA, Manstein DJ. Mechanism, regulation, and functional properties of Dictyostelium myosin-1B. The Journal of Biological Chemistry. 283: 4520-7. PMID 18089562 DOI: 10.1074/Jbc.M708113200 |
0.426 |
|
2008 |
Coulton AT, Koka K, Lehrer SS, Geeves MA. Role of the head-to-tail overlap region in smooth and skeletal muscle beta-tropomyosin. Biochemistry. 47: 388-97. PMID 18069797 DOI: 10.1021/Bi701144G |
0.402 |
|
2008 |
Maytum R, Hatch V, Konrad M, Lehman W, Geeves MA. Ultra short yeast tropomyosins show novel myosin regulation. The Journal of Biological Chemistry. 283: 1902-10. PMID 18006493 DOI: 10.1074/Jbc.M708593200 |
0.434 |
|
2007 |
Bloemink MJ, Adamek N, Reggiani C, Geeves MA. Kinetic analysis of the slow skeletal myosin MHC-1 isoform from bovine masseter muscle. Journal of Molecular Biology. 373: 1184-97. PMID 17900618 DOI: 10.1016/J.Jmb.2007.08.050 |
0.401 |
|
2007 |
Boussouf SE, Agianian B, Bullard B, Geeves MA. The regulation of myosin binding to actin filaments by Lethocerus troponin. Journal of Molecular Biology. 373: 587-98. PMID 17868693 DOI: 10.1016/J.Jmb.2007.07.066 |
0.392 |
|
2007 |
Skoumpla K, Coulton AT, Lehman W, Geeves MA, Mulvihill DP. Acetylation regulates tropomyosin function in the fission yeast Schizosaccharomyces pombe. Journal of Cell Science. 120: 1635-45. PMID 17452625 DOI: 10.1242/Jcs.001115 |
0.43 |
|
2007 |
Málnási-Csizmadia A, Tóth J, Pearson DS, Hetényi C, Nyitray L, Geeves MA, Bagshaw CR, Kovács M. Selective perturbation of the myosin recovery stroke by point mutations at the base of the lever arm affects ATP hydrolysis and phosphate release. The Journal of Biological Chemistry. 282: 17658-64. PMID 17449872 DOI: 10.1074/Jbc.M701447200 |
0.618 |
|
2007 |
Boussouf SE, Maytum R, Jaquet K, Geeves MA. Role of tropomyosin isoforms in the calcium sensitivity of striated muscle thin filaments. Journal of Muscle Research and Cell Motility. 28: 49-58. PMID 17436057 DOI: 10.1007/S10974-007-9103-Z |
0.39 |
|
2007 |
Miller BM, Bloemink MJ, Nyitrai M, Bernstein SI, Geeves MA. A variable domain near the ATP-binding site in Drosophila muscle myosin is part of the communication pathway between the nucleotide and actin-binding sites. Journal of Molecular Biology. 368: 1051-66. PMID 17379245 DOI: 10.1016/J.Jmb.2007.02.042 |
0.417 |
|
2007 |
Boussouf SE, Geeves MA. Tropomyosin and troponin cooperativity on the thin filament. Advances in Experimental Medicine and Biology. 592: 99-109. PMID 17278359 DOI: 10.1007/978-4-431-38453-3_10 |
0.431 |
|
2007 |
Kintses B, Gyimesi M, Pearson DS, Geeves MA, Zeng W, Bagshaw CR, Málnási-Csizmadia A. Reversible movement of switch 1 loop of myosin determines actin interaction. The Embo Journal. 26: 265-74. PMID 17213877 DOI: 10.1038/Sj.Emboj.7601482 |
0.655 |
|
2007 |
Iorga B, Adamek N, Geeves MA. The slow skeletal muscle isoform of myosin shows kinetic features common to smooth and non-muscle myosins. The Journal of Biological Chemistry. 282: 3559-70. PMID 17130133 DOI: 10.1074/Jbc.M608191200 |
0.458 |
|
2006 |
Coulton A, Lehrer SS, Geeves MA. Functional homodimers and heterodimers of recombinant smooth muscle tropomyosin. Biochemistry. 45: 12853-8. PMID 17042503 DOI: 10.1021/Bi0613224 |
0.393 |
|
2006 |
Adio S, Bloemink M, Hartel M, Leier S, Geeves MA, Woehlke G. Kinetic and mechanistic basis of the nonprocessive Kinesin-3 motor NcKin3. The Journal of Biological Chemistry. 281: 37782-93. PMID 17012747 DOI: 10.1074/Jbc.M605061200 |
0.332 |
|
2006 |
Herm-Götz A, Delbac F, Weiss S, Nyitrai M, Stratmann R, Tomavo S, Sibley LD, Geeves MA, Soldati D. Functional and biophysical analyses of the class XIV Toxoplasma gondii myosin D. Journal of Muscle Research and Cell Motility. 27: 139-51. PMID 16470333 DOI: 10.1007/S10974-005-9046-1 |
0.321 |
|
2006 |
Dürrwang U, Fujita-Becker S, Erent M, Kull FJ, Tsiavaliaris G, Geeves MA, Manstein DJ. Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis. Journal of Cell Science. 119: 550-8. PMID 16443752 DOI: 10.1242/Jcs.02774 |
0.377 |
|
2006 |
Kremneva E, Nikolaeva O, Maytum R, Arutyunyan AM, Kleimenov SY, Geeves MA, Levitsky DI. Thermal unfolding of smooth muscle and nonmuscle tropomyosin alpha-homodimers with alternatively spliced exons. The Febs Journal. 273: 588-600. PMID 16420482 DOI: 10.1111/J.1742-4658.2005.05092.X |
0.318 |
|
2006 |
Nyitrai M, Rossi R, Adamek N, Pellegrino MA, Bottinelli R, Geeves MA. What limits the velocity of fast-skeletal muscle contraction in mammals? Journal of Molecular Biology. 355: 432-42. PMID 16325202 DOI: 10.1016/J.Jmb.2005.10.063 |
0.416 |
|
2005 |
Geeves MA, Holmes KC. The molecular mechanism of muscle contraction. Advances in Protein Chemistry. 71: 161-93. PMID 16230112 DOI: 10.1016/S0065-3233(04)71005-0 |
0.455 |
|
2005 |
Nalavadi V, Nyitrai M, Bertolini C, Adamek N, Geeves MA, Bähler M. Kinetic mechanism of myosin IXB and the contributions of two class IX-specific regions. The Journal of Biological Chemistry. 280: 38957-68. PMID 16179355 DOI: 10.1074/Jbc.M507161200 |
0.467 |
|
2005 |
Clark R, Ansari MA, Dash S, Geeves MA, Coluccio LM. Loop 1 of transducer region in mammalian class I myosin, Myo1b, modulates actin affinity, ATPase activity, and nucleotide access. The Journal of Biological Chemistry. 280: 30935-42. PMID 15980431 DOI: 10.1074/Jbc.M504698200 |
0.466 |
|
2005 |
Geeves MA, Fedorov R, Manstein DJ. Molecular mechanism of actomyosin-based motility. Cellular and Molecular Life Sciences : Cmls. 62: 1462-77. PMID 15924264 DOI: 10.1007/S00018-005-5015-5 |
0.418 |
|
2005 |
Fujita-Becker S, Dürrwang U, Erent M, Clark RJ, Geeves MA, Manstein DJ. Changes in Mg2+ ion concentration and heavy chain phosphorylation regulate the motor activity of a class I myosin. The Journal of Biological Chemistry. 280: 6064-71. PMID 15579903 DOI: 10.1074/Jbc.M412473200 |
0.371 |
|
2004 |
Nyitrai M, Geeves MA. Adenosine diphosphate and strain sensitivity in myosin motors. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 359: 1867-77. PMID 15647162 DOI: 10.1098/Rstb.2004.1560 |
0.399 |
|
2004 |
Kremneva E, Boussouf S, Nikolaeva O, Maytum R, Geeves MA, Levitsky DI. Effects of two familial hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on the thermal unfolding of actin-bound tropomyosin. Biophysical Journal. 87: 3922-33. PMID 15454401 DOI: 10.1529/Biophysj.104.048793 |
0.309 |
|
2004 |
Shimada A, Nyitrai M, Vetter IR, Kühlmann D, Bugyi B, Narumiya S, Geeves MA, Wittinghofer A. The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization. Molecular Cell. 13: 511-22. PMID 14992721 DOI: 10.1016/S1097-2765(04)00059-0 |
0.381 |
|
2004 |
Maytum R, Bathe F, Konrad M, Geeves MA. Tropomyosin exon 6b is troponin-specific and required for correct acto-myosin regulation. The Journal of Biological Chemistry. 279: 18203-9. PMID 14752114 DOI: 10.1074/Jbc.M311636200 |
0.422 |
|
2004 |
Crevel IM, Nyitrai M, Alonso MC, Weiss S, Geeves MA, Cross RA. What kinesin does at roadblocks: the coordination mechanism for molecular walking. The Embo Journal. 23: 23-32. PMID 14685258 DOI: 10.1038/Sj.Emboj.7600042 |
0.375 |
|
2004 |
Málnási-Csizmadia A, Pearson DS, Kovács M, Woolley RJ, Geeves MA, Bagshaw CR. Kinetic Resolution of a Conformational Transition and the ATP Hydrolysis Step Using Relaxation Methods with aDictyosteliumMyosin II Mutant Containing a Single Tryptophan Residue Biochemistry. 43: 14316-14316. DOI: 10.1021/Bi040043I |
0.603 |
|
2003 |
Silva R, Sparrow JC, Geeves MA. Isolation and kinetic characterisation of myosin and myosin S1 from the Drosophila indirect flight muscles. Journal of Muscle Research and Cell Motility. 24: 489-98. PMID 14870964 DOI: 10.1023/B:Jure.0000009809.69829.74 |
0.473 |
|
2003 |
Clark RJ, Nyitrai M, Webb MR, Geeves MA. Probing nucleotide dissociation from myosin in vitro using microgram quantities of myosin. Journal of Muscle Research and Cell Motility. 24: 315-21. PMID 14620745 DOI: 10.1023/A:1025481908301 |
0.466 |
|
2003 |
Miller BM, Nyitrai M, Bernstein SI, Geeves MA. Kinetic analysis of Drosophila muscle myosin isoforms suggests a novel mode of mechanochemical coupling. The Journal of Biological Chemistry. 278: 50293-300. PMID 14506231 DOI: 10.1074/Jbc.M308318200 |
0.479 |
|
2003 |
Nyitrai M, Stafford WF, Szent-Györgyi AG, Geeves MA. Ionic interactions play a role in the regulatory mechanism of scallop heavy meromyosin. Biophysical Journal. 85: 1053-62. PMID 12885652 DOI: 10.1016/S0006-3495(03)74544-5 |
0.361 |
|
2003 |
Smith DA, Geeves MA. Cooperative regulation of myosin-actin interactions by a continuous flexible chain II: actin-tropomyosin-troponin and regulation by calcium. Biophysical Journal. 84: 3168-80. PMID 12719246 DOI: 10.1016/S0006-3495(03)70041-1 |
0.444 |
|
2003 |
Smith DA, Maytum R, Geeves MA. Cooperative regulation of myosin-actin interactions by a continuous flexible chain I: actin-tropomyosin systems. Biophysical Journal. 84: 3155-67. PMID 12719245 DOI: 10.1016/S0006-3495(03)70040-X |
0.457 |
|
2003 |
Maytum R, Westerdorf B, Jaquet K, Geeves MA. Differential regulation of the actomyosin interaction by skeletal and cardiac troponin isoforms. The Journal of Biological Chemistry. 278: 6696-701. PMID 12475978 DOI: 10.1074/Jbc.M210690200 |
0.414 |
|
2003 |
Nyitrai M, Szent-Györgyi AG, Geeves MA. Interactions of the two heads of scallop (Argopecten irradians) heavy meromyosin with actin: influence of calcium and nucleotides. The Biochemical Journal. 370: 839-48. PMID 12441001 DOI: 10.1042/Bj20021519 |
0.442 |
|
2002 |
Tsiavaliaris G, Fujita-Becker S, Batra R, Levitsky DI, Kull FJ, Geeves MA, Manstein DJ. Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium. Embo Reports. 3: 1099-105. PMID 12393751 DOI: 10.1093/Embo-Reports/Kvf214 |
0.371 |
|
2002 |
Geeves MA, Trentham DR. Proteins: from chemical to physiological mechanism. European Biophysics Journal : Ebj. 31: 243-4. PMID 12122470 DOI: 10.1007/S00249-002-0231-5 |
0.546 |
|
2002 |
Nyitrai M, Szent-Györgyi AG, Geeves MA. A kinetic model of the co-operative binding of calcium and ADP to scallop (Argopecten irradians) heavy meromyosin. The Biochemical Journal. 365: 19-30. PMID 12071838 DOI: 10.1042/Bj20020099 |
0.336 |
|
2002 |
Maytum R, Geeves MA, Lehrer SS. A modulatory role for the troponin T tail domain in thin filament regulation. The Journal of Biological Chemistry. 277: 29774-80. PMID 12045197 DOI: 10.1074/Jbc.M201761200 |
0.484 |
|
2002 |
Pearson DS, Holtermann G, Ellison P, Cremo C, Geeves MA. A novel pressure-jump apparatus for the microvolume analysis of protein-ligand and protein-protein interactions: its application to nucleotide binding to skeletal-muscle and smooth-muscle myosin subfragment-1. The Biochemical Journal. 366: 643-51. PMID 12010120 DOI: 10.1042/Bj20020462 |
0.436 |
|
2002 |
Herm-Götz A, Weiss S, Stratmann R, Fujita-Becker S, Ruff C, Meyhöfer E, Soldati T, Manstein DJ, Geeves MA, Soldati D. Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor. The Embo Journal. 21: 2149-58. PMID 11980712 DOI: 10.1093/Emboj/21.9.2149 |
0.381 |
|
2002 |
Geeves MA, Lehrer SS. Modeling thin filament cooperativity [1] (multiple letters) Biophysical Journal. 82: 1677-1681. PMID 11898795 DOI: 10.1016/S0006-3495(02)75518-5 |
0.326 |
|
2002 |
Geeves MA, Lehrer SS. Cooperativity in the Ca2+ regulation of muscle contraction Results and Problems in Cell Differentiation. 36: 111-132. PMID 11892276 DOI: 10.1007/978-3-540-46558-4_10 |
0.39 |
|
2001 |
Málnási-Csizmadia A, Pearson DS, Kovács M, Woolley RJ, Geeves MA, Bagshaw CR. Kinetic resolution of a conformational transition and the ATP hydrolysis step using relaxation methods with a Dictyostelium myosin II mutant containing a single tryptophan residue. Biochemistry. 40: 12727-37. PMID 11601998 DOI: 10.1021/Bi010963Q |
0.638 |
|
2001 |
Weiss S, Rossi R, Pellegrino MA, Bottinelli R, Geeves MA. Differing ADP release rates from myosin heavy chain isoforms define the shortening velocity of skeletal muscle fibers. The Journal of Biological Chemistry. 276: 45902-8. PMID 11590173 DOI: 10.1074/Jbc.M107434200 |
0.386 |
|
2001 |
Rogers KR, Weiss S, Crevel I, Brophy PJ, Geeves M, Cross R. KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry. The Embo Journal. 20: 5101-13. PMID 11566875 DOI: 10.1093/Emboj/20.18.5101 |
0.354 |
|
2001 |
Maytum R, Konrad M, Lehrer SS, Geeves MA. Regulatory properties of tropomyosin effects of length, isoform, and N-terminal sequence. Biochemistry. 40: 7334-41. PMID 11401582 DOI: 10.1021/Bi010072I |
0.416 |
|
2001 |
Berger CE, Fagnant PM, Heizmann S, Trybus KM, Geeves MA. ADP binding induces an asymmetry between the heads of unphosphorylated myosin. The Journal of Biological Chemistry. 276: 23240-5. PMID 11301326 DOI: 10.1074/Jbc.M100524200 |
0.456 |
|
2001 |
Lohmann K, Westerdorf B, Maytum R, Geeves MA, Jaquet K. Overexpression of human cardiac troponin in Escherichia coli: its purification and characterization. Protein Expression and Purification. 21: 49-59. PMID 11162386 DOI: 10.1006/Prep.2000.1328 |
0.35 |
|
2000 |
Weiss S, Chizhov I, Geeves MA. A flash photolysis fluorescence/light scattering apparatus for use with sub microgram quantities of muscle proteins. Journal of Muscle Research and Cell Motility. 21: 423-32. PMID 11129433 DOI: 10.1023/A:1005690106951 |
0.452 |
|
2000 |
Maytum R, Geeves MA, Konrad M. Actomyosin regulatory properties of yeast tropomyosin are dependent upon N-terminal modification. Biochemistry. 39: 11913-20. PMID 11009604 DOI: 10.1021/Bi000977G |
0.424 |
|
2000 |
Furch M, Remmel B, Geeves MA, Manstein DJ. Stabilization of the actomyosin complex by negative charges on myosin. Biochemistry. 39: 11602-8. PMID 10995227 DOI: 10.1021/Bi000985X |
0.348 |
|
2000 |
Lehman W, Hatch V, Korman V, Rosol M, Thomas L, Maytum R, Geeves MA, Van Eyk JE, Tobacman LS, Craig R. Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments. Journal of Molecular Biology. 302: 593-606. PMID 10986121 DOI: 10.1006/Jmbi.2000.4080 |
0.489 |
|
2000 |
Geeves MA, Chai M, Lehrer SS. Inhibition of actin-myosin subfragment 1 ATPase activity by troponin I and IC: Relationship to the thin filament states of muscle Biochemistry. 39: 9345-9350. PMID 10924128 DOI: 10.1021/Bi0002232 |
0.38 |
|
2000 |
Holmes KC, Geeves MA. The structural basis of muscle contraction. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 419-31. PMID 10836495 DOI: 10.1098/Rstb.2000.0583 |
0.494 |
|
2000 |
Geeves MA, Perreault-Micale C, Coluccio LM. Kinetic analyses of a truncated mammalian myosin I suggest a novel isomerization event preceding nucleotide binding. The Journal of Biological Chemistry. 275: 21624-30. PMID 10781577 DOI: 10.1074/Jbc.M000342200 |
0.405 |
|
2000 |
Schmitz S, Clayton J, Nongthomba U, Prinz H, Veigel C, Geeves M, Sparrow J. Drosophila ACT88F indirect flight muscle-specific actin is not N-terminally acetylated: a mutation in N-terminal processing affects actin function. Journal of Molecular Biology. 295: 1201-10. PMID 10653697 DOI: 10.1006/Jmbi.1999.3407 |
0.373 |
|
1999 |
Geeves MA, Holmes KC. Structural mechanism of muscle contraction. Annual Review of Biochemistry. 68: 687-728. PMID 10872464 DOI: 10.1146/Annurev.Biochem.68.1.687 |
0.451 |
|
1999 |
Geeves MA, Coluccio LM. The XXVIII European Muscle conference. York, UK, 4-7 September 1999. Journal of Muscle Research and Cell Motility. 20: 807-9. PMID 10730583 DOI: 10.1023/A:1005604902375 |
0.334 |
|
1999 |
Vawda F, Geeves MA, Ranatunga KW. Force generation upon hydrostatic pressure release in tetanized intact frog muscle fibres. Journal of Muscle Research and Cell Motility. 20: 477-88. PMID 10555066 DOI: 10.1023/A:1005565917768 |
0.33 |
|
1999 |
Razzaq A, Schmitz S, Veigel C, Molloy JE, Geeves MA, Sparrow JC. Actin residue glu(93) is identified as an amino acid affecting myosin binding. The Journal of Biological Chemistry. 274: 28321-8. PMID 10497190 DOI: 10.1074/Jbc.274.40.28321 |
0.457 |
|
1999 |
Coluccio LM, Geeves MA. Transient kinetic analysis of the 130-kDa myosin I (MYR-1 gene product) from rat liver. A myosin I designed for maintenance of tension? The Journal of Biological Chemistry. 274: 21575-80. PMID 10419463 DOI: 10.1074/Jbc.274.31.21575 |
0.461 |
|
1999 |
Schaertl S, Geeves MA, Konrad M. Human nucleoside diphosphate kinase B (Nm23-H2) from melanoma cells shows altered phosphoryl transfer activity due to the S122P mutation. The Journal of Biological Chemistry. 274: 20159-64. PMID 10400630 DOI: 10.1074/Jbc.274.29.20159 |
0.325 |
|
1999 |
Furch M, Fujita-Becker S, Geeves MA, Holmes KC, Manstein DJ. Role of the salt-bridge between switch-1 and switch-2 of Dictyostelium myosin. Journal of Molecular Biology. 290: 797-809. PMID 10395830 DOI: 10.1006/Jmbi.1999.2921 |
0.404 |
|
1999 |
Batra R, Geeves MA, Manstein DJ. Kinetic analysis of Dictyostelium discoideum myosin motor domains with glycine-to-alanine mutations in the reactive thiol region. Biochemistry. 38: 6126-34. PMID 10320339 DOI: 10.1021/Bi982251E |
0.38 |
|
1999 |
Reiffert S, Maytum R, Geeves M, Lohmann K, Greis T, Blüggel M, Meyer HE, Heilmeyer LM, Jaquet K. Characterization of the cardiac holotroponin complex reconstituted from native cardiac troponin T and recombinant I and C. European Journal of Biochemistry. 261: 40-7. PMID 10103031 DOI: 10.1046/J.1432-1327.1999.00261.X |
0.347 |
|
1999 |
Jacob M, Holtermann G, Perl D, Reinstein J, Schindler T, Geeves MA, Schmid FX. Microsecond folding of the cold shock protein measured by a pressure- jump technique Biochemistry. 38: 2882-2891. PMID 10074340 DOI: 10.1021/Bi982487I |
0.333 |
|
1999 |
Maytum R, Lehrer SS, Geeves MA. Cooperativity and switching within the three-state model of muscle regulation. Biochemistry. 38: 1102-10. PMID 9894007 DOI: 10.1021/Bi981603E |
0.419 |
|
1998 |
Geeves MA, Chizhov I. The use of fast kinetic systems for the study of ng-microgram quantities of purified muscle proteins. Advances in Experimental Medicine and Biology. 453: 79-88; discussion 88. PMID 9889817 DOI: 10.1007/978-1-4684-6039-1_10 |
0.437 |
|
1998 |
Conibear PB, Geeves MA. Cooperativity between the two heads of rabbit skeletal muscle heavy meromyosin in binding to actin. Biophysical Journal. 75: 926-37. PMID 9675193 DOI: 10.1016/S0006-3495(98)77581-2 |
0.455 |
|
1998 |
Friedman AL, Geeves MA, Manstein DJ, Spudich JA. Kinetic characterization of myosin head fragments with long-lived myosin.ATP states. Biochemistry. 37: 9679-87. PMID 9657680 DOI: 10.1021/Bi973143F |
0.464 |
|
1998 |
Kurzawa-Goertz SE, Perreault-Micale CL, Trybus KM, Szent-Györgyi AG, Geeves MA. Loop I can modulate ADP affinity, ATPase activity, and motility of different scallop myosins. Transient kinetic analysis of S1 isoforms. Biochemistry. 37: 7517-25. PMID 9585566 DOI: 10.1021/Bi972844+ |
0.449 |
|
1998 |
Furch M, Geeves MA, Manstein DJ. Modulation of actin affinity and actomyosin adenosine triphosphatase by charge changes in the myosin motor domain. Biochemistry. 37: 6317-26. PMID 9572846 DOI: 10.1021/Bi972851Y |
0.43 |
|
1998 |
Lehrer SS, Geeves MA. The muscle thin filament as a classical cooperative/allosteric regulatory system Journal of Molecular Biology. 277: 1081-1089. PMID 9571024 DOI: 10.1006/Jmbi.1998.1654 |
0.493 |
|
1998 |
Levitsky DI, Ponomarev MA, Geeves MA, Shnyrov VL, Manstein DJ. Differential scanning calorimetric study of the thermal unfolding of the motor domain fragments of Dictyostelium discoideum myosin II. European Journal of Biochemistry. 251: 275-80. PMID 9492294 DOI: 10.1046/J.1432-1327.1998.2510275.X |
0.384 |
|
1998 |
Schaertl S, Konrad M, Geeves MA. Substrate specificity of human nucleoside-diphosphate kinase revealed by transient kinetic analysis. The Journal of Biological Chemistry. 273: 5662-9. PMID 9488696 DOI: 10.1074/Jbc.273.10.5662 |
0.315 |
|
1998 |
Cremo CR, Geeves MA. Interaction of actin and ADP with the head domain of smooth muscle myosin: implications for strain-dependent ADP release in smooth muscle. Biochemistry. 37: 1969-78. PMID 9485324 DOI: 10.1021/Bi9722406 |
0.446 |
|
1997 |
Lehrer SS, Golitsina NL, Geeves MA. Actin-tropomyosin activation of myosin subfragment 1 ATPase and thin filament cooperativity. The role of tropomyosin flexibility and end-to-end interactions. Biochemistry. 36: 13449-54. PMID 9354612 DOI: 10.1021/Bi971568W |
0.433 |
|
1997 |
Kurzawa SE, Manstein DJ, Geeves MA. Dictyostelium discoideum myosin II: characterization of functional myosin motor fragments. Biochemistry. 36: 317-23. PMID 9003183 DOI: 10.1021/Bi962166B |
0.345 |
|
1996 |
Kurzawa SE, Geeves MA. A novel stopped-flow method for measuring the affinity of actin for myosin head fragments using microgram quantities of protein. Journal of Muscle Research and Cell Motility. 17: 669-76. PMID 8994086 DOI: 10.1007/Bf00154061 |
0.4 |
|
1996 |
Vawda F, Ranatunga KW, Geeves MA. Effects of hydrostatic pressure on fatiguing frog muscle fibres. Journal of Muscle Research and Cell Motility. 17: 631-6. PMID 8994082 DOI: 10.1007/Bf00154057 |
0.32 |
|
1996 |
Reiffert SU, Jaquet K, Heilmeyer LM, Ritchie MD, Geeves MA. Bisphosphorylation of cardiac troponin I modulates the Ca(2+)-dependent binding of myosin subfragment S1 to reconstituted thin filaments. Febs Letters. 384: 43-7. PMID 8797800 DOI: 10.1016/0014-5793(96)00274-8 |
0.429 |
|
1996 |
Anson M, Geeves MA, Kurzawa SE, Manstein DJ. Myosin motors with artificial lever arms. The Embo Journal. 15: 6069-6074. DOI: 10.1002/J.1460-2075.1996.Tb00995.X |
0.394 |
|
1995 |
Smith DA, Geeves MA. Strain-dependent cross-bridge cycle for muscle. II. Steady-state behavior. Biophysical Journal. 69: 538-52. PMID 8527668 DOI: 10.1016/S0006-3495(95)79927-1 |
0.42 |
|
1995 |
Smith DA, Geeves MA. Strain-dependent cross-bridge cycle for muscle. Biophysical Journal. 69: 524-37. PMID 8527667 DOI: 10.1016/S0006-3495(95)79926-X |
0.394 |
|
1995 |
Woodward SK, Geeves MA, Manstein DJ. Kinetic characterization of the catalytic domain of Dictyostelium discoideum myosin. Biochemistry. 34: 16056-64. PMID 8519762 DOI: 10.1021/Bi00049A020 |
0.429 |
|
1995 |
Schaertl S, Lehrer SS, Geeves MA. Separation and characterization of the two functional regions of troponin involved in muscle thin filament regulation. Biochemistry. 34: 15890-4. PMID 8519745 DOI: 10.1021/Bi00049A003 |
0.438 |
|
1995 |
Head JG, Ritchie MD, Geeves MA. Characterization of the equilibrium between blocked and closed states of muscle thin filaments. European Journal of Biochemistry. 227: 694-9. PMID 7867627 DOI: 10.1111/J.1432-1033.1995.0694P.X |
0.394 |
|
1995 |
Geeves MA, Conibear PB, Lombardi V, Kawai M, Cooke R, Baskin R, Huxley H, Moore K, Hackney D. The role of three-state docking of myosin S1 with actin in force generation Biophysical Journal. 68: 194s-201s. PMID 7787067 |
0.334 |
|
1995 |
Anson M, Drummond DR, Geeves MA, Hennessey ES, Ritchie MD, Sparrow JC. Actomyosin kinetics and in vitro motility of wild-type Drosophila actin and the effects of two mutations in the Act88F gene. Biophysical Journal. 68: 1991-2003. PMID 7612841 DOI: 10.1016/S0006-3495(95)80376-0 |
0.46 |
|
1995 |
Geeves MA, Branson JP, Attwood PV. Kinetics of nucleotide binding to pyruvate carboxylase. Biochemistry. 34: 11846-54. PMID 7547919 DOI: 10.1021/Bi00037A024 |
0.374 |
|
1995 |
Vawda F, Ranatunga KW, Geeves MA. Pressure-induced changes in the isometric contractions of single intact frog muscle fibres at low temperatures. Journal of Muscle Research and Cell Motility. 16: 412-9. PMID 7499481 DOI: 10.1007/Bf00114506 |
0.326 |
|
1994 |
Fortune NS, Geeves MA, Ranatunga KW. Contractile activation and force generation in skinned rabbit muscle fibres: effects of hydrostatic pressure. The Journal of Physiology. 474: 283-90. PMID 8006815 DOI: 10.1113/Jphysiol.1994.Sp020021 |
0.363 |
|
1994 |
McKillop DF, Fortune NS, Ranatunga KW, Geeves MA. The influence of 2,3-butanedione 2-monoxime (BDM) on the interaction between actin and myosin in solution and in skinned muscle fibres. Journal of Muscle Research and Cell Motility. 15: 309-18. PMID 7929796 DOI: 10.1007/Bf00123483 |
0.459 |
|
1994 |
Geeves MA, Lehrer SS. Dynamics of the muscle thin filament regulatory switch: The size of the cooperative unit Biophysical Journal. 67: 273-282. PMID 7918995 DOI: 10.1016/S0006-3495(94)80478-3 |
0.461 |
|
1993 |
Ritchie MD, Geeves MA, Woodward SK, Manstein DJ. Kinetic characterization of a cytoplasmic myosin motor domain expressed in Dictyostelium discoideum. Proceedings of the National Academy of Sciences of the United States of America. 90: 8619-23. PMID 8378339 DOI: 10.1073/Pnas.90.18.8619 |
0.493 |
|
1993 |
Knight PJ, Fortune NS, Geeves MA. Effects of pressure on equatorial x-ray fiber diffraction from skeletal muscle fibers. Biophysical Journal. 65: 814-22. PMID 8218906 DOI: 10.1016/S0006-3495(93)81111-1 |
0.332 |
|
1993 |
McKillop DF, Geeves MA. Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament. Biophysical Journal. 65: 693-701. PMID 8218897 DOI: 10.1016/S0006-3495(93)81110-X |
0.401 |
|
1992 |
Ranatunga KW, Geeves MA. Changes produced by increased hydrostatic pressure in isometric contractions of rat fast muscle. The Journal of Physiology. 441: 423-31. PMID 1816380 DOI: 10.1113/Jphysiol.1991.Sp018759 |
0.321 |
|
1992 |
Geeves MA. The actomyosin ATPase: a two-state system. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 336: 63-70; discussion 70. PMID 1351298 DOI: 10.1098/Rstb.1992.0045 |
0.45 |
|
1991 |
Geeves MA, Goldmann WH. The influence of anions, ionic strength and organic solvents on the interaction between actin and myosin subfragment 1. Biochemical Society Transactions. 18: 584-5. PMID 2276448 DOI: 10.1042/Bst0180584 |
0.318 |
|
1991 |
Ranatunga KW, Fortune NS, Geeves MA. Hydrostatic compression in glycerinated rabbit muscle fibers. Biophysical Journal. 58: 1401-10. PMID 2275960 DOI: 10.1016/S0006-3495(90)82486-3 |
0.315 |
|
1991 |
McKillop DF, Geeves MA. Regulation of the acto.myosin subfragment 1 interaction by troponin/tropomyosin. Evidence for control of a specific isomerization between two acto.myosin subfragment 1 states. The Biochemical Journal. 279: 711-8. PMID 1953663 DOI: 10.1042/Bj2790711 |
0.462 |
|
1991 |
Geeves MA. The influence of pressure on actin and myosin interactions in solution and in single muscle fibres. Journal of Cell Science. Supplement. 14: 31-5. PMID 1885656 DOI: 10.1242/Jcs.1991.Supplement_14.7 |
0.378 |
|
1991 |
Fortune NS, Geeves MA, Ranatunga KW. Tension responses to rapid pressure release in glycerinated rabbit muscle fibers. Proceedings of the National Academy of Sciences of the United States of America. 88: 7323-7. PMID 1871140 DOI: 10.1073/Pnas.88.16.7323 |
0.336 |
|
1991 |
McKillop DF, Geeves MA, Balny C. The effect of hydrostatic pressure on the interaction of actomyosin subfragment 1 with nucleotides. Biochemical and Biophysical Research Communications. 180: 552-7. PMID 1835384 DOI: 10.1016/S0006-291X(05)81100-3 |
0.361 |
|
1991 |
Geeves MA. The dynamics of actin and myosin association and the crossbridge model of muscle contraction. The Biochemical Journal. 1-14. PMID 1825780 DOI: 10.1042/Bj2740001 |
0.398 |
|
1991 |
Woodward SK, Eccleston JF, Geeves MA. Kinetics of the interaction of 2'(3')-O-(N-methylanthraniloyl)-ATP with myosin subfragment 1 and actomyosin subfragment 1: characterization of two acto-S1-ADP complexes. Biochemistry. 30: 422-30. PMID 1824820 DOI: 10.1021/Bi00216A017 |
0.335 |
|
1991 |
Cross RA, Geeves MA, Kendrick-Jones J. A nucleation - Elongation mechanism for the self-assembly of side polar sheets of smooth muscle myosin Embo Journal. 10: 747-756. DOI: 10.1002/J.1460-2075.1991.Tb08006.X |
0.395 |
|
1990 |
McKillop DF, Geeves MA. Effect of phosphate and sulphate on the interaction of actin and myosin subfragment 1. Biochemical Society Transactions. 18: 585-6. PMID 2276449 DOI: 10.1042/Bst0180585 |
0.378 |
|
1990 |
Nesterov VP, Peiper U, Hiller J, Krienke B, Schüttler K, Szymanski C, Bottinelli R, Cappelli V, Minelli R, Reggiani C, Schiaffino S, Carlhoff D, D'Haese J, Dabrowska R, Nowak E, ... ... Geeves MA, ... ... Geeves M, et al. Abstracts of the XVIII European Conference on Muscle and Motility Journal of Muscle Research & Cell Motility. 11: 56-78. DOI: 10.1007/Bf01833326 |
0.61 |
|
1989 |
Geeves MA. Dynamic interaction between actin and myosin subfragment 1 in the presence of ADP. Biochemistry. 28: 5864-71. PMID 2528376 DOI: 10.1021/Bi00440A024 |
0.359 |
|
1988 |
Millar NC, Geeves MA. Protein fluorescence changes associated with ATP and adenosine 5'-[gamma-thio]triphosphate binding to skeletal muscle myosin subfragment 1 and actomyosin subfragment 1. The Biochemical Journal. 249: 735-43. PMID 3355494 DOI: 10.1042/Bj2490735 |
0.404 |
|
1988 |
Geeves MA, Jeffries TE. The effect of nucleotide upon a specific isomerization of actomyosin subfragment 1 Biochemical Journal. 256: 41-46. PMID 3223909 DOI: 10.1042/Bj2560041 |
0.47 |
|
1988 |
Geeves MA, Ranatunga KW. Tension responses to increased hydrostatic pressure in glycerinated rabbit psoas muscle fibres. Proceedings of the Royal Society of London. Series B, Biological Sciences. 232: 217-26. PMID 2892206 DOI: 10.1098/Rspb.1987.0070 |
0.344 |
|
1987 |
Geeves MA, Jeffries TE, Millar NC. ATP-induced dissociation of rabbit skeletal actomyosin subfragment 1. Characterization of an isomerization of the ternary acto-S1-ATP complex. Biochemistry. 25: 8454-8. PMID 3828289 DOI: 10.1021/Bi00374A020 |
0.381 |
|
1987 |
Geeves MA, Halsall DJ. Two-step ligand binding and cooperativity. A model to describe the cooperative binding of myosin subfragment 1 to regulated actin. Biophysical Journal. 52: 215-20. PMID 3663829 DOI: 10.1016/S0006-3495(87)83208-3 |
0.433 |
|
1986 |
Geeves MA, Halsall DJ. The dynamics of the interaction between myosin subfragment 1 and pyrene-labelled thin filaments, from rabbit skeletal muscle. Proceedings of the Royal Society of London. Series B, Biological Sciences. 229: 85-95. PMID 2878438 DOI: 10.1098/Rspb.1986.0076 |
0.443 |
|
1985 |
Coates JH, Criddle AH, Geeves MA. Pressure-relaxation studies of pyrene-labelled actin and myosin subfragment 1 from rabbit skeletal muscle. Evidence for two states of acto-subfragment 1. The Biochemical Journal. 232: 351-6. PMID 4091793 DOI: 10.1042/Bj2320351 |
0.419 |
|
1985 |
Criddle AH, Geeves MA, Jeffries T. The use of actin labelled with N-(1-pyrenyl)iodoacetamide to study the interaction of actin with myosin subfragments and troponin/tropomyosin Biochemical Journal. 232: 343-349. PMID 3911945 DOI: 10.1042/Bj2320343 |
0.406 |
|
1984 |
Geeves MA, Goody RS, Gutfreund H. Kinetics of acto-S1 interaction as a guide to a model for the crossbridge cycle. Journal of Muscle Research and Cell Motility. 5: 351-61. PMID 6237117 DOI: 10.1007/Bf00818255 |
0.752 |
|
1983 |
Millar NC, Geeves MA. The limiting rate of the ATP-mediated dissociation of actin from rabbit skeletal muscle myosin subfragment 1. Febs Letters. 160: 141-8. PMID 6884503 DOI: 10.1016/0014-5793(83)80954-5 |
0.435 |
|
1982 |
Geeves MA, Gutfreund H. The use of pressure perturbations to investigate the interaction of rabbit muscle myosin subfragment 1 with actin in the presence of MgADP. Febs Letters. 140: 11-5. PMID 7084449 DOI: 10.1016/0014-5793(82)80509-7 |
0.406 |
|
1982 |
Geeves MA, Trentham DR. Protein-bound adenosine 5'-triphosphate: properties of a key intermediate of the magnesium-dependent subfragment 1 adenosinetriphosphatase from rabbit skeletal muscle. Biochemistry. 21: 2782-9. PMID 6124272 DOI: 10.1021/Bi00540A032 |
0.653 |
|
1980 |
Geeves MA, Webb MR, Midelfort CF, Trentham DR. Mechanism of adenosine 5'-triphosphate cleavage by myosin: studies with oxygen-18-labeled adenosine 5'-triphosphate. Biochemistry. 19: 4748-54. PMID 6448633 |
0.552 |
|
1979 |
Fink AL, Geeves MA. Cryoenzymology: the study of enzyme catalysis at subzero temperatures. Methods in Enzymology. 63: 336-70. PMID 41158 DOI: 10.1016/0076-6879(79)63015-X |
0.503 |
|
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