Leslie A. Leinwand - Publications

Affiliations: 
Molecular, Cellular and Developmental Biology University of Colorado, Boulder, Boulder, CO, United States 
Area:
Medical Biophysics, Physiology Biology, Biochemistry

227 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Vera CD, Johnson CA, Walklate J, Adhikari A, Svicevic M, Mijailovich SM, Combs AC, Langer SJ, Ruppel KM, Spudich JA, Geeves MA, Leinwand LA. Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties. The Journal of Biological Chemistry. PMID 31582565 DOI: 10.1074/jbc.RA119.010563  0.6
2019 Johnson CA, Walklate J, Svicevic M, Mijailovich SM, Vera CD, Karabina A, Leinwand LA, Geeves MA. The ATPase cycle of human muscle myosin II Isoforms: adaptation of a single mechanochemical cycle for different physiological roles. The Journal of Biological Chemistry. PMID 31387944 DOI: 10.1074/jbc.RA119.009825  0.6
2018 Ujfalusi Z, Vera CD, Mijailovich SM, Svicevic M, Yu EC, Kawana M, Ruppel K, Spudich JA, Geeves MA, Leinwand LA. Dilated cardiomyopathy myosin mutants have reduced force-generating capacity. The Journal of Biological Chemistry. PMID 29666183 DOI: 10.1074/jbc.RA118.001938  0.6
2017 Luckey SW, Haines CD, Konhilas JP, Luczak ED, Messmer-Kratzsch A, Leinwand LA. Cyclin D2 is a critical mediator of exercise-induced cardiac hypertrophy. Experimental Biology and Medicine (Maywood, N.J.). 1535370217731503. PMID 28901173 DOI: 10.1177/1535370217731503  0.36
2017 Vega RB, Konhilas JP, Kelly DP, Leinwand LA. Molecular Mechanisms Underlying Cardiac Adaptation to Exercise. Cell Metabolism. 25: 1012-1026. PMID 28467921 DOI: 10.1016/j.cmet.2017.04.025  0.36
2016 Peter AK, Bjerke MA, Leinwand LA. Biology of the cardiac myocyte in heart disease. Molecular Biology of the Cell. 27: 2149-60. PMID 27418636 DOI: 10.1091/mbc.E16-01-0038  1
2016 Pugach EK, Blenck CL, Dragavon JM, Langer SJ, Leinwand LA. Estrogen receptor profiling and activity in cardiac myocytes. Molecular and Cellular Endocrinology. PMID 27164442 DOI: 10.1016/j.mce.2016.05.004  1
2016 Blenck CL, Harvey PA, Reckelhoff JF, Leinwand LA. The Importance of Biological Sex and Estrogen in Rodent Models of Cardiovascular Health and Disease. Circulation Research. 118: 1294-312. PMID 27081111 DOI: 10.1161/CIRCRESAHA.116.307509  1
2016 Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, et al. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science (New York, N.Y.). 351: 617-21. PMID 26912705 DOI: 10.1126/science.aad3456  1
2015 Nag S, Sommese RF, Ujfalusi Z, Combs A, Langer S, Sutton S, Leinwand LA, Geeves MA, Ruppel KM, Spudich JA. Contractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function. Science Advances. 1: e1500511. PMID 26601291 DOI: 10.1126/sciadv.1500511  0.6
2015 Schiaffino S, Rossi AC, Smerdu V, Leinwand LA, Reggiani C. Developmental myosins: expression patterns and functional significance. Skeletal Muscle. 5: 22. PMID 26180627 DOI: 10.1186/s13395-015-0046-6  1
2015 Taylor KC, Buvoli M, Korkmaz EN, Buvoli A, Zheng Y, Heinze NT, Cui Q, Leinwand LA, Rayment I. Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly. Proceedings of the National Academy of Sciences of the United States of America. PMID 26150528 DOI: 10.1073/pnas.1505813112  1
2015 Pugach EK, Richmond PA, Azofeifa JG, Dowell RD, Leinwand LA. Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic. Journal of Molecular and Cellular Cardiology. 86: 54-61. PMID 26141530 DOI: 10.1016/j.yjmcc.2015.06.019  1
2015 Harvey PA, Leinwand LA. Oestrogen enhances cardiotoxicity induced by Sunitinib by regulation of drug transport and metabolism. Cardiovascular Research. 107: 66-77. PMID 26009590 DOI: 10.1093/cvr/cvv152  1
2015 Hajj GP, Chu Y, Lund DD, Magida JA, Funk ND, Brooks RM, Baumbach GL, Zimmerman KA, Davis MK, El Accaoui RN, Hameed T, Doshi H, Chen B, Leinwand LA, Song LS, et al. Spontaneous Aortic Regurgitation and Valvular Cardiomyopathy in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1653-62. PMID 25997932 DOI: 10.1161/ATVBAHA.115.305729  1
2015 Guess MG, Barthel KK, Harrison BC, Leinwand LA. miR-30 family microRNAs regulate myogenic differentiation and provide negative feedback on the microRNA pathway. Plos One. 10: e0118229. PMID 25689854 DOI: 10.1371/journal.pone.0118229  1
2015 Haizlip KM, Harrison BC, Leinwand LA. Sex-based differences in skeletal muscle kinetics and fiber-type composition. Physiology (Bethesda, Md.). 30: 30-9. PMID 25559153 DOI: 10.1152/physiol.00024.2014  1
2015 Harvey PA, Leinwand LA. Dietary phytoestrogens present in soy dramatically increase cardiotoxicity in male mice receiving a chemotherapeutic tyrosine kinase inhibitor. Molecular and Cellular Endocrinology. 399: 330-5. PMID 25458703 DOI: 10.1016/j.mce.2014.10.011  1
2015 Konhilas JP, Chen H, Luczak E, McKee LA, Regan J, Watson PA, Stauffer BL, Khalpey ZI, Mckinsey TA, Horn T, LaFleur B, Leinwand LA. Diet and sex modify exercise and cardiac adaptation in the mouse. American Journal of Physiology. Heart and Circulatory Physiology. 308: H135-45. PMID 25398983 DOI: 10.1152/ajpheart.00532.2014  1
2014 Harvey PA, Wall C, Luckey SW, Langer S, Leinwand LA. The python project: a unique model for extending research opportunities to undergraduate students. Cbe Life Sciences Education. 13: 698-710. PMID 25452492 DOI: 10.1187/cbe.14-05-0089  1
2014 Wang H, Leinwand LA, Anseth KS. Cardiac valve cells and their microenvironment--insights from in vitro studies. Nature Reviews. Cardiology. 11: 715-27. PMID 25311230 DOI: 10.1038/nrcardio.2014.162  1
2014 Wang H, Leinwand LA, Anseth KS. Roles of transforming growth factor-β1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4551-62. PMID 25008089 DOI: 10.1096/fj.14-254623  1
2014 Burns KM, Byrne BJ, Gelb BD, Kühn B, Leinwand LA, Mital S, Pearson GD, Rodefeld M, Rossano JW, Stauffer BL, Taylor MD, Towbin JA, Redington AN. New mechanistic and therapeutic targets for pediatric heart failure: report from a National Heart, Lung, and Blood Institute working group. Circulation. 130: 79-86. PMID 24982119 DOI: 10.1161/CIRCULATIONAHA.113.007980  1
2014 Magida JA, Leinwand LA. Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy. Embo Molecular Medicine. 6: 482-95. PMID 24567073 DOI: 10.1002/emmm.201302852  1
2014 Chung E, Leinwand LA. Pregnancy as a cardiac stress model. Cardiovascular Research. 101: 561-70. PMID 24448313 DOI: 10.1093/cvr/cvu013  1
2014 Harvey PA, Leinwand LA. Cardiac Atrophy and Remodeling Cellular and Molecular Pathobiology of Cardiovascular Disease. 37-50. DOI: 10.1016/B978-0-12-405206-2.00003-X  1
2013 Kucherlapati R, Leinwand LA. Frank Ruddle (1929-2013). American Journal of Human Genetics. 92: 839-40. PMID 24242788 DOI: 10.1016/j.ajhg.2013.05.012  1
2013 Wang H, Tibbitt MW, Langer SJ, Leinwand LA, Anseth KS. Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway. Proceedings of the National Academy of Sciences of the United States of America. 110: 19336-41. PMID 24218588 DOI: 10.1073/pnas.1306369110  1
2013 Chung E, Yeung F, Leinwand LA. Calcineurin activity is required for cardiac remodelling in pregnancy. Cardiovascular Research. 100: 402-10. PMID 23985902 DOI: 10.1093/cvr/cvt208  1
2013 Wang H, Sridhar B, Leinwand LA, Anseth KS. Characterization of cell subpopulations expressing progenitor cell markers in porcine cardiac valves. Plos One. 8: e69667. PMID 23936071 DOI: 10.1371/journal.pone.0069667  1
2013 Guess MG, Barthel KK, Pugach EK, Leinwand LA. Measuring microRNA reporter activity in skeletal muscle using hydrodynamic limb vein injection of plasmid DNA combined with in vivo imaging. Skeletal Muscle. 3: 19. PMID 23915674 DOI: 10.1186/2044-5040-3-19  1
2013 Bloemink MJ, Deacon JC, Resnicow DI, Leinwand LA, Geeves MA. The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms. The Journal of Biological Chemistry. 288: 27469-79. PMID 23908353 DOI: 10.1074/jbc.M113.488130  1
2013 Sommese RF, Sung J, Nag S, Sutton S, Deacon JC, Choe E, Leinwand LA, Ruppel K, Spudich JA. Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function. Proceedings of the National Academy of Sciences of the United States of America. 110: 12607-12. PMID 23798412 DOI: 10.1073/pnas.1309493110  1
2013 Leinwand LA, Harrison BC. Young at heart. Cell. 153: 743-5. PMID 23663775 DOI: 10.1016/j.cell.2013.04.038  1
2013 Xu R, Andres-Mateos E, Mejias R, MacDonald EM, Leinwand LA, Merriman DK, Fink RH, Cohn RD. Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization. Experimental Neurology. 247: 392-401. PMID 23333568 DOI: 10.1016/j.expneurol.2013.01.005  1
2013 Andres-Mateos E, Brinkmeier H, Burks TN, Mejias R, Files DC, Steinberger M, Soleimani A, Marx R, Simmers JL, Lin B, Finanger Hedderick E, Marr TG, Lin BM, Hourdé C, Leinwand LA, et al. Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy. Embo Molecular Medicine. 5: 80-91. PMID 23161797 DOI: 10.1002/emmm.201201443  1
2013 Barthel KKB, Harvey PA, Leinwand LA. Diet and exercise are potent modulators of cardiovascular disease in women Integrative Biology of Women's Health. 175-204. DOI: 10.1007/978-1-4614-8630-5_10  1
2012 Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, ... Leinwand LA, et al. A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 151: 1319-31. PMID 23217713 DOI: 10.1016/j.cell.2012.10.050  1
2012 Andres-Mateos E, Mejias R, Soleimani A, Lin BM, Burks TN, Marx R, Lin B, Zellars RC, Zhang Y, Huso DL, Marr TG, Leinwand LA, Merriman DK, Cohn RD. Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels. Plos One. 7: e48884. PMID 23155423 DOI: 10.1371/journal.pone.0048884  1
2012 Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 492: 285-9. PMID 23103865 DOI: 10.1038/nature11648  1
2012 Cosper PF, Harvey PA, Leinwand LA. Interferon-γ causes cardiac myocyte atrophy via selective degradation of myosin heavy chain in a model of chronic myocarditis. The American Journal of Pathology. 181: 2038-46. PMID 23058369 DOI: 10.1016/j.ajpath.2012.08.040  1
2012 Deacon JC, Bloemink MJ, Rezavandi H, Geeves MA, Leinwand LA. Erratum to: Identification of functional differences between recombinant human α and β cardiac myosin motors. Cellular and Molecular Life Sciences : Cmls. 69: 4239-55. PMID 23001010 DOI: 10.1007/s00018-012-1111-5  0.6
2012 Chung E, Heimiller J, Leinwand LA. Distinct cardiac transcriptional profiles defining pregnancy and exercise. Plos One. 7: e42297. PMID 22860109 DOI: 10.1371/journal.pone.0042297  1
2012 Wang H, Haeger SM, Kloxin AM, Leinwand LA, Anseth KS. Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. Plos One. 7: e39969. PMID 22808079 DOI: 10.1371/journal.pone.0039969  1
2012 Haines CD, Harvey PA, Luczak ED, Barthel KK, Konhilas JP, Watson PA, Stauffer BL, Leinwand LA. Estrogenic compounds are not always cardioprotective and can be lethal in males with genetic heart disease. Endocrinology. 153: 4470-9. PMID 22778230 DOI: 10.1210/en.2012-1391  1
2012 Leinwand LA, Tardiff JC, Gregorio CC. Mutations in the sensitive giant titin result in a broken heart. Circulation Research. 111: 158-61. PMID 22773424 DOI: 10.1161/RES.0b013e3182635ca2  1
2012 Haines CD, Harvey PA, Leinwand LA. Estrogens mediate cardiac hypertrophy in a stimulus-dependent manner. Endocrinology. 153: 4480-90. PMID 22759381 DOI: 10.1210/en.2012-1353  1
2012 Thompson RC, Buvoli M, Buvoli A, Leinwand LA. Myosin filament assembly requires a cluster of four positive residues located in the rod domain. Febs Letters. 586: 3008-12. PMID 22728135 DOI: 10.1016/j.febslet.2012.06.019  1
2012 Yeung F, Chung E, Guess MG, Bell ML, Leinwand LA. Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Research. 40: 7303-18. PMID 22638570 DOI: 10.1093/nar/gks466  1
2012 Spangenburg EE, Geiger PC, Leinwand LA, Lowe DA. Regulation of physiological and metabolic function of muscle by female sex steroids. Medicine and Science in Sports and Exercise. 44: 1653-62. PMID 22525764 DOI: 10.1249/MSS.0b013e31825871fa  1
2012 Deacon JC, Bloemink MJ, Rezavandi H, Geeves MA, Leinwand LA. Identification of functional differences between recombinant human α and β cardiac myosin motors. Cellular and Molecular Life Sciences : Cmls. 69: 2261-77. PMID 22349210 DOI: 10.1007/s00018-012-0927-3  1
2012 Chung E, Yeung F, Leinwand LA. Akt and MAPK signaling mediate pregnancy-induced cardiac adaptation. Journal of Applied Physiology (Bethesda, Md. : 1985). 112: 1564-75. PMID 22345431 DOI: 10.1152/japplphysiol.00027.2012  1
2012 Buvoli M, Buvoli A, Leinwand LA. Effects of pathogenic proline mutations on myosin assembly. Journal of Molecular Biology. 415: 807-18. PMID 22155079 DOI: 10.1016/j.jmb.2011.11.042  1
2012 Cosper PF, Leinwand LA. Myosin heavy chain is not selectively decreased in murine cancer cachexia. International Journal of Cancer. 130: 2722-7. PMID 21796617 DOI: 10.1002/ijc.26298  1
2012 Solaro RJ, Leinwand LA. Role of sarcomeres in cellular tension, shortening, and signaling in cardiac muscle Muscle. 1: 161-172. DOI: 10.1016/B978-0-12-381510-1.00013-2  1
2011 Anderson WA, Amasino RM, Ares M, Banerjee U, Bartel B, Corces VG, Drennan CL, Elgin SC, Epstein IR, Fanning E, Guillette LJ, Handelsman J, Hatfull GF, Hoy RR, Kelley D, ... Leinwand LA, et al. Competencies: a cure for pre-med curriculum. Science (New York, N.Y.). 334: 760-1. PMID 22076362 DOI: 10.1126/science.334.6057.760-b  1
2011 Riquelme CA, Magida JA, Harrison BC, Wall CE, Marr TG, Secor SM, Leinwand LA. Fatty acids identified in the Burmese python promote beneficial cardiac growth. Science (New York, N.Y.). 334: 528-31. PMID 22034436 DOI: 10.1126/science.1210558  1
2011 Harvey PA, Leinwand LA. The cell biology of disease: cellular mechanisms of cardiomyopathy. The Journal of Cell Biology. 194: 355-65. PMID 21825071 DOI: 10.1083/jcb.201101100  1
2011 Harrison BC, Allen DL, Leinwand LA. IIb or not IIb? Regulation of myosin heavy chain gene expression in mice and men. Skeletal Muscle. 1: 5. PMID 21798083 DOI: 10.1186/2044-5040-1-5  1
2011 Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. Journal of Molecular and Cellular Cardiology. 51: 41-50. PMID 21539845 DOI: 10.1016/j.yjmcc.2011.04.005  1
2011 Luczak ED, Barthel KK, Stauffer BL, Konhilas JP, Cheung TH, Leinwand LA. Remodeling the cardiac transcriptional landscape with diet. Physiological Genomics. 43: 772-80. PMID 21487031 DOI: 10.1152/physiolgenomics.00237.2010  1
2011 Leinwand LA, Moss RL. Medicine. Chemically tuned myosin motors. Science (New York, N.Y.). 331: 1392-3. PMID 21415340 DOI: 10.1126/science.1204207  1
2011 Cosper PF, Leinwand LA. Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner. Cancer Research. 71: 1710-20. PMID 21163868 DOI: 10.1158/0008-5472.CAN-10-3145  1
2011 Wall CE, Cozza S, Riquelme CA, McCombie WR, Heimiller JK, Marr TG, Leinwand LA. Whole transcriptome analysis of the fasting and fed Burmese python heart: Insights into extreme physiological cardiac adaptation Physiological Genomics. 43: 69-76. PMID 21045117 DOI: 10.1152/physiolgenomics.00162.2010  1
2010 Konhilas JP, Boucek DM, Horn TR, Johnson GL, Leinwand LA. The role of MEKK1 in hypertrophic cardiomyopathy. International Heart Journal. 51: 277-84. PMID 20716846 DOI: JST.JSTAGE/ihj/51.277  1
2010 Bell ML, Buvoli M, Leinwand LA. Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping. Molecular and Cellular Biology. 30: 1937-45. PMID 20154144 DOI: 10.1128/MCB.01370-09  1
2010 Bhupathy P, Haines CD, Leinwand LA. Influence of sex hormones and phytoestrogens on heart disease in men and women Women's Health (London, England). 6: 77-95. PMID 20088732 DOI: 10.2217/whe.09.80  1
2010 Resnicow DI, Deacon JC, Warrick HM, Spudich JA, Leinwand LA. Functional diversity among a family of human skeletal muscle myosin motors. Proceedings of the National Academy of Sciences of the United States of America. 107: 1053-8. PMID 20080549 DOI: 10.1073/pnas.0913527107  1
2010 Armel TZ, Leinwand LA. A mutation in the beta-myosin rod associated with hypertrophic cardiomyopathy has an unexpected molecular phenotype. Biochemical and Biophysical Research Communications. 391: 352-6. PMID 19913502 DOI: 10.1016/j.bbrc.2009.11.062  1
2010 Armel TZ, Leinwand LA. Mutations at the same amino acid in myosin that cause either skeletal or cardiac myopathy have distinct molecular phenotypes. Journal of Molecular and Cellular Cardiology. 48: 1007-13. PMID 19854198 DOI: 10.1016/j.yjmcc.2009.10.011  1
2010 Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, ... ... Leinwand LA, et al. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain, Behavior, and Immunity. 24: 83-95. PMID 19679181 DOI: 10.1016/j.bbi.2009.08.004  0.32
2010 Hamady M, Buvoli M, Leinwand LA, Knight R. Estimate of the abundance of cardiomyopathic mutations in the β-myosin gene. International Journal of Cardiology. 144: 124-6. PMID 19174318 DOI: 10.1016/j.ijcard.2008.12.199  1
2010 Resnicow DI, Deacon JC, Warrick HM, Spudich JA, Leinwand LA. Functional diversity among a family of human skeletal muscle myosin motors (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 3 (1053-1058) DOI: 10.1073/pnas.0913527107) Proceedings of the National Academy of Sciences of the United States of America. 107: 10765. DOI: 10.1073/pnas.1005980107  1
2010 Chung E, Leinwand LA. Genetic Determinants of Exercise Performance: Evidence from Transgenic and Null Mouse Models Genetic and Molecular Aspects of Sport Performance. 185-194. DOI: 10.1002/9781444327335.ch16  1
2009 Benton JA, Kern HB, Leinwand LA, Mariner PD, Anseth KS. Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1950-7. PMID 19679827 DOI: 10.1161/ATVBAHA.109.195271  1
2009 Hughes TS, Langer SJ, Virtanen SI, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression. The Journal of Gene Medicine. 11: 782-90. PMID 19533588 DOI: 10.1002/jgm.1364  1
2009 Armel TZ, Leinwand LA. Mutations in the beta-myosin rod cause myosin storage myopathy via multiple mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 106: 6291-6. PMID 19336582 DOI: 10.1073/pnas.0900107106  1
2009 Luckey SW, Walker LA, Smyth T, Mansoori J, Messmer-Kratzsch A, Rosenzweig A, Olson EN, Leinwand LA. The role of Akt/GSK-3β signaling in familial hypertrophic cardiomyopathy Journal of Molecular and Cellular Cardiology. 46: 739-747. PMID 19233194 DOI: 10.1016/j.yjmcc.2009.02.010  1
2009 Hughes TS, Langer SJ, Johnson KW, Chavez RA, Watkins LR, Milligan ED, Leinwand LA. Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 88-94. PMID 18941439 DOI: 10.1038/mt.2008.230  1
2009 Luczak ED, Leinwand LA. Sex-based cardiac physiology. Annual Review of Physiology. 71: 1-18. PMID 18828746 DOI: 10.1146/annurev.physiol.010908.163156  1
2008 Chung E, Leinwand LA. Rescuing cardiac malfunction: the roles of the chaperone-like small heat shock proteins. Circulation Research. 103: 1351-3. PMID 19059837 DOI: 10.1161/CIRCRESAHA.108.189720  1
2008 Buvoli M, Hamady M, Leinwand LA, Knight R. Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations. Trends in Cardiovascular Medicine. 18: 141-9. PMID 18555187 DOI: 10.1016/j.tcm.2008.04.001  1
2008 Resnicow DI, Hooft AM, Harrison BC, Baker JE, Leinwand LA. GFP fails to inhibit actin-myosin interactions in vitro. Nature Methods. 5: 212-3; author reply . PMID 18309305 DOI: 10.1038/nmeth0308-212  1
2008 Harrison BC, Leinwand LA. Fighting fat with muscle: bulking up to slim down. Cell Metabolism. 7: 97-8. PMID 18249167 DOI: 10.1016/j.cmet.2008.01.003  1
2008 Jensen DR, Knaub LA, Konhilas JP, Leinwand LA, MacLean PS, Eckel RH. Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: An avian phenotype? Journal of Lipid Research. 49: 870-879. PMID 18175800 DOI: 10.1194/jlr.M700519-JLR200  1
2007 Konhilas JP, Leinwand LA. The effects of biological sex and diet on the development of heart failure. Circulation. 116: 2747-59. PMID 18056540 DOI: 10.1161/CIRCULATIONAHA.106.672006  1
2007 Sheren J, Langer SJ, Leinwand LA. A randomized library approach to identifying functional lox site domains for the Cre recombinase. Nucleic Acids Research. 35: 5464-73. PMID 17702764 DOI: 10.1093/nar/gkm604  1
2007 Buvoli M, Buvoli A, Leinwand LA. Interplay between exonic splicing enhancers, mRNA processing, and mRNA surveillance in the dystrophic Mdx mouse. Plos One. 2: e427. PMID 17487273 DOI: 10.1371/journal.pone.0000427  1
2007 Watson PA, Reusch JE, McCune SA, Leinwand LA, Luckey SW, Konhilas JP, Brown DA, Chicco AJ, Sparagna GC, Long CS, Moore RL. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. American Journal of Physiology. Heart and Circulatory Physiology. 293: H246-59. PMID 17337597 DOI: 10.1152/ajpheart.00734.2006  1
2007 Benoit DS, Tripodi MC, Blanchette JO, Langer SJ, Leinwand LA, Anseth KS. Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells. Journal of Biomedical Materials Research. Part A. 81: 259-68. PMID 17335036 DOI: 10.1002/jbm.a.31292  1
2007 Leinwand LA. Molecular events underlying pregnancy-induced cardiomyopathy. Cell. 128: 437-8. PMID 17289564 DOI: 10.1016/j.cell.2007.01.020  1
2007 Ledeboer A, Jekich BM, Sloane EM, Mahoney JH, Langer SJ, Milligan ED, Martin D, Maier SF, Johnson KW, Leinwand LA, Chavez RA, Watkins LR. Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain, Behavior, and Immunity. 21: 686-98. PMID 17174526 DOI: 10.1016/j.bbi.2006.10.012  1
2007 Luckey SW, Mansoori J, Fair K, Antos CL, Olson EN, Leinwand LA. Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males. American Journal of Physiology. Heart and Circulatory Physiology. 292: H838-45. PMID 17012357 DOI: 10.1152/ajpheart.00615.2006  1
2006 Milligan ED, Soderquist RG, Malone SM, Mahoney JH, Hughes TS, Langer SJ, Sloane EM, Maier SF, Leinwand LA, Watkins LR, Mahoney MJ. Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. Neuron Glia Biology. 2: 293-308. PMID 18079973 DOI: 10.1017/S1740925X07000488  1
2006 Voelkel NF, Quaife RA, Leinwand LA, Barst RJ, McGoon MD, Meldrum DR, Dupuis J, Long CS, Rubin LJ, Smart FW, Suzuki YJ, Gladwin M, Denholm EM, Gail DB. Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation. 114: 1883-91. PMID 17060398 DOI: 10.1161/CIRCULATIONAHA.106.632208  1
2006 Geurts AM, Collier LS, Geurts JL, Oseth LL, Bell ML, Mu D, Lucito R, Godbout SA, Green LE, Lowe SW, Hirsch BA, Leinwand LA, Largaespada DA. Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. Plos Genetics. 2: e156. PMID 17009875 DOI: 10.1371/journal.pgen.0020156  1
2006 Milligan ED, Sloane EM, Langer SJ, Hughes TS, Jekich BM, Frank MG, Mahoney JH, Levkoff LH, Maier SF, Cruz PE, Flotte TR, Johnson KW, Mahoney MM, Chavez RA, Leinwand LA, et al. Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain. 126: 294-308. PMID 16949747 DOI: 10.1016/j.pain.2006.07.009  1
2006 Dennehey BK, Leinwand LA, Krauter KS. Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts. Journal of Muscle Research and Cell Motility. 27: 559-75. PMID 16819597 DOI: 10.1007/s10974-006-9071-8  1
2006 Konhilas JP, Leinwand LA. Partnering up for cardiac hypertrophy. Circulation Research. 98: 985-7. PMID 16645146 DOI: 10.1161/01.RES.0000221823.31424.47  1
2006 Beylkin DH, Allen DL, Leinwand LA. MyoD, Myf5, and the calcineurin pathway activate the developmental myosin heavy chain genes. Developmental Biology. 294: 541-53. PMID 16584724 DOI: 10.1016/j.ydbio.2006.02.049  1
2006 Konhilas JP, Watson PA, Maass A, Boucek DM, Horn T, Stauffer BL, Luckey SW, Rosenberg P, Leinwand LA. Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy. Circulation Research. 98: 540-8. PMID 16439687 DOI: 10.1161/01.RES.0000205766.97556.00  0.36
2006 Stauffer BL, Konhilas JP, Luczak ED, Leinwand LA. Soy diet worsens heart disease in mice. The Journal of Clinical Investigation. 116: 209-16. PMID 16395406 DOI: 10.1172/JCI24676  1
2005 Cushing MC, Jaeggli MP, Masters KS, Leinwand LA, Anseth KS. Serum deprivation improves seeding and repopulation of acellular matrices with valvular interstitial cells. Journal of Biomedical Materials Research. Part A. 75: 232-41. PMID 16088888 DOI: 10.1002/jbm.a.30412  1
2005 Milligan ED, Langer SJ, Sloane EM, He L, Wieseler-Frank J, O'Connor K, Martin D, Forsayeth JR, Maier SF, Johnson K, Chavez RA, Leinwand LA, Watkins LR. Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. The European Journal of Neuroscience. 21: 2136-48. PMID 15869510 DOI: 10.1111/j.1460-9568.2005.04057.x  1
2005 Milligan ED, Sloane EM, Langer SJ, Cruz PE, Chacur M, Spataro L, Wieseler-Frank J, Hammack SE, Maier SF, Flotte TR, Forsayeth JR, Leinwand LA, Chavez R, Watkins LR. Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Molecular Pain. 1: 9. PMID 15813997 DOI: 10.1186/1744-8069-1-9  1
2005 Konhilas JP, Widegren U, Allen DL, Paul AC, Cleary A, Leinwand LA. Loaded wheel running and muscle adaptation in the mouse. American Journal of Physiology. Heart and Circulatory Physiology. 289: H455-65. PMID 15734890 DOI: 10.1152/ajpheart.00085.2005  1
2005 Allen DL, Weber JN, Sycuro LK, Leinwand LA. Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo. The Journal of Biological Chemistry. 280: 17126-34. PMID 15728583 DOI: 10.1074/jbc.M501207200  1
2005 Masters KS, Shah DN, Leinwand LA, Anseth KS. Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials. 26: 2517-25. PMID 15585254 DOI: 10.1016/j.biomaterials.2004.07.018  1
2005 Mariner PD, Luckey SW, Long CS, Sucharov CC, Leinwand LA. Yin Yang 1 represses alpha-myosin heavy chain gene expression in pathologic cardiac hypertrophy. Biochemical and Biophysical Research Communications. 326: 79-86. PMID 15567155 DOI: 10.1016/j.bbrc.2004.11.008  1
2004 Maass AH, Ikeda K, Oberdorf-Maass S, Maier SK, Leinwand LA. Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T. Circulation. 110: 2102-9. PMID 15466629 DOI: 10.1161/01.CIR.0000144460.84795.E3  1
2004 Masters KS, Shah DN, Walker G, Leinwand LA, Anseth KS. Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials. Journal of Biomedical Materials Research. Part A. 71: 172-80. PMID 15368267 DOI: 10.1002/jbm.a.30149  1
2004 Konhilas JP, Maass AH, Luckey SW, Stauffer BL, Olson EN, Leinwand LA. Sex modifies exercise and cardiac adaptation in mice. American Journal of Physiology. Heart and Circulatory Physiology. 287: H2768-76. PMID 15319208 DOI: 10.1152/ajpheart.00292.2004  1
2004 Walker GA, Masters KS, Shah DN, Anseth KS, Leinwand LA. Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circulation Research. 95: 253-60. PMID 15217906 DOI: 10.1161/01.RES.0000136520.07995.aa  1
2004 Stelzer JE, Patel JR, Olsson MC, Fitzsimons DP, Leinwand LA, Moss RL. Expression of cardiac troponin T with COOH-terminal truncation accelerates cross-bridge interaction kinetics in mouse myocardium. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1756-61. PMID 15165990 DOI: 10.1152/ajpheart.00172.2004  1
2004 Olsson MC, Palmer BM, Stauffer BL, Leinwand LA, Moore RL. Morphological and functional alterations in ventricular myocytes from male transgenic mice with hypertrophic cardiomyopathy. Circulation Research. 94: 201-7. PMID 14670849 DOI: 10.1161/01.RES.0000111521.40760.18  1
2004 Stauffer BL, Leinwand LA. Sex differences in cardiac muscle and remodeling Advances in Molecular and Cell Biology. 34: 131-145. DOI: 10.1016/S1569-2558(03)34010-X  1
2003 Rice NA, Leinwand LA. Skeletal myosin heavy chain function in cultured lung myofibroblasts. The Journal of Cell Biology. 163: 119-29. PMID 14557251 DOI: 10.1083/jcb.200303194  1
2003 Leinwand LA. Hope for a broken heart? Cell. 114: 658-9. PMID 14505565 DOI: 10.1016/S0092-8674(03)00718-9  1
2003 Maass AH, Leinwand LA. Mechanisms of the pathogenesis of troponin T-based familial hypertrophic cardiomyopathy. Trends in Cardiovascular Medicine. 13: 232-7. PMID 12922019 DOI: 10.1016/S1050-1738(03)00100-2  1
2003 Leinwand LA. Sex is a potent modifier of the cardiovascular system. The Journal of Clinical Investigation. 112: 302-7. PMID 12897194 DOI: 10.1172/JCI19429  1
2003 Haubold KW, Allen DL, Capetanaki Y, Leinwand LA. Loss of desmin leads to impaired voluntary wheel running and treadmill exercise performance. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 1617-22. PMID 12844497 DOI: 10.1152/japplphysiol.00408.2003  1
2003 Maass A, Langer SJ, Oberdorf-Maass S, Bauer S, Neyses L, Leinwand LA. Rational promoter selection for gene transfer into cardiac cells. Journal of Molecular and Cellular Cardiology. 35: 823-31. PMID 12818573 DOI: 10.1016/S0022-2828(03)00140-8  1
2003 Weisbart RH, Yang F, Chan G, Wakelin R, Ferreri K, Zack DJ, Harrison B, Leinwand LA, Cole GM. Cell type specific targeted intracellular delivery into muscle of a monoclonal antibody that binds myosin IIb. Molecular Immunology. 39: 783-9. PMID 12617993 DOI: 10.1016/S0161-5890(03)00003-8  1
2003 Buvoli M, Buvoli A, Leinwand LA. Suppressor tRNAs: protocols and applications for cardiac gene transfer. Methods in Molecular Biology (Clifton, N.J.). 219: 115-27. PMID 12597002  1
2003 Haubold K, Herrmann H, Langer SJ, Evans RM, Leinwand LA, Klymkowsky MW. Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes. Cell Motility and the Cytoskeleton. 54: 105-21. PMID 12529857 DOI: 10.1002/cm.10090  1
2003 Lucas DT, Aryal P, Szweda LI, Koch WJ, Leinwand LA. Alterations in mitochondrial function in a mouse model of hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 284: H575-83. PMID 12414446 DOI: 10.1152/ajpheart.00619.2002  1
2002 Maass A, Konhilas JP, Stauffer BL, Leinwand LA. From sarcomeric mutations to heart disease: Understanding familial hypertrophic cardiomyopathy Cold Spring Harbor Symposia On Quantitative Biology. 67: 409-415. PMID 12858566  1
2002 Allen DL, Leinwand LA. Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter. The Journal of Biological Chemistry. 277: 45323-30. PMID 12235157 DOI: 10.1074/jbc.M208302200  1
2002 Allen DL, Harrison BC, Leinwand LA. Molecular and genetic approaches to studying exercise performance and adaptation. Exercise and Sport Sciences Reviews. 30: 99-105. PMID 12150574  1
2002 Lerman I, Harrison BC, Freeman K, Hewett TE, Allen DL, Robbins J, Leinwand LA. Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 2245-55. PMID 12015333 DOI: 10.1152/japplphysiol.01045.2001  1
2002 Buvoli M, Leinwand LA. Direct gene transfer into mouse heart. Methods in Enzymology. 346: 134-42. PMID 11883064 DOI: 10.1016/S0076-6879(02)46053-3  1
2002 Buvoli M, Langer SJ, Bialik S, Leinwand LA. Potential limitations of transcription terminators used as transgene insulators in adenoviral vectors Gene Therapy. 9: 227-231. PMID 11859427 DOI: 10.1038/sj/gt/3301640  1
2002 Harrison BC, Bell ML, Allen DL, Byrnes WC, Leinwand LA. Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 313-22. PMID 11744674 DOI: 10.1152/japplphysiol.00832.2001  1
2001 Allen DL, Sartorius CA, Sycuro LK, Leinwand LA. Different pathways regulate expression of the skeletal myosin heavy chain genes. The Journal of Biological Chemistry. 276: 43524-33. PMID 11551968 DOI: 10.1074/jbc.M108017200  1
2001 Freeman K, Nakao K, Leinwand LA. Low sequence variation in the gene encoding the human β-myosin heavy chain Genomics. 76: 73-80. PMID 11549319 DOI: 10.1006/geno.2001.6573  1
2001 Maass A, Leinwand LA. A role for calreticulin in the adult heart? Journal of Clinical Investigation. 107: 1223-1225. PMID 11375411  1
2001 Allen DL, Harrison BC, Maass A, Bell ML, Byrnes WC, Leinwand LA. Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse. Journal of Applied Physiology (Bethesda, Md. : 1985). 90: 1900-8. PMID 11299284  1
2001 Leinwand LA. Calcineurin inhibition and cardiac hypertrophy: A matter of balance Proceedings of the National Academy of Sciences of the United States of America. 98: 2947-2949. PMID 11248009 DOI: 10.1073/pnas.051033698  1
2001 Walker GA, Guerrero IA, Leinwand LA. Myofibroblasts: molecular crossdressers. Current Topics in Developmental Biology. 51: 91-107. PMID 11236717  1
2001 Olsson MC, Palmer BM, Leinwand LA, Moore RL. Gender and aging in a transgenic mouse model of hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 280: H1136-44. PMID 11179057  1
2001 Allen DL, Harrison BC, Sartorius C, Byrnes WC, Leinwand LA. Mutation of the IIB myosin heavy chain gene results in muscle fiber loss and compensatory hypertrophy. American Journal of Physiology. Cell Physiology. 280: C637-45. PMID 11171584  1
2001 Chandra M, Rundell VLM, Tardiff JC, Leinwand LA, De Tombe PP, Solaro RJ. Ca2+ activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin t American Journal of Physiology - Heart and Circulatory Physiology. 280: H705-H713. PMID 11158969  1
2001 Allen DL, Leinwand LA. Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains. Developmental Biology. 229: 383-95. PMID 11150240 DOI: 10.1006/dbio.2000.9974  1
2000 Allen DL, Harrison BC, Leinwand LA. Inactivation of myosin heavy chain genes in the mouse: diverse and unexpected phenotypes. Microscopy Research and Technique. 50: 492-9. PMID 10998638 DOI: 10.1002/1097-0029(20000915)50:6<492::AID-JEMT6>3.0.CO;2-J  1
2000 Maass A, Leinwand LA. Animal models of hypertrophic cardiomyopathy Current Opinion in Cardiology. 15: 189-196. PMID 10952427 DOI: 10.1097/00001573-200005000-00012  1
2000 Buvoli A, Buvoli M, Leinwand LA. Enhanced detection of tRNA isoacceptors by combinatorial oligonucleotide hybridization Rna. 6: 912-918. PMID 10864048 DOI: 10.1017/S1355838200000339  1
2000 Buvoli M, Buvoli A, Leinwand LA. Suppression of nonsense mutations in cell culture and mice by multimerized suppressor tRNA genes Molecular and Cellular Biology. 20: 3116-3124. PMID 10757796 DOI: 10.1128/MCB.20.9.3116-3124.2000  1
2000 Miyata S, Minobe W, Bristow MR, Leinwand LA. Myosin heavy chain isoform expression in the failing and nonfailing human heart Circulation Research. 86: 386-390. PMID 10700442  1
2000 Tardiff JC, Hewett TE, Factor SM, Vikstrom KL, Robbins J, Leinwand LA. Expression of the β (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects American Journal of Physiology - Heart and Circulatory Physiology. 278. PMID 10666070  1
1999 Lu BD, Allen DL, Leinwand LA, Lyons GE. Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development. Developmental Biology. 216: 312-26. PMID 10588881 DOI: 10.1006/dbio.1999.9488  1
1999 Weiss A, Schiaffino S, Leinwand LA. Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: Implications for functional diversity Journal of Molecular Biology. 290: 61-75. PMID 10388558 DOI: 10.1006/jmbi.1999.2865  1
1998 Roopnarine O, Leinwand LA. Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy. Biophysical Journal. 75: 3023-30. PMID 9826622 DOI: 10.1016/S0006-3495(98)77743-4  1
1998 Sartorius CA, Lu BD, Acakpo-Satchivi L, Jacobsen RP, Byrnes WC, Leinwand LA. Myosin heavy chains IIa and IId are functionally distinct in the mouse Journal of Cell Biology. 141: 943-953. PMID 9585413 DOI: 10.1083/jcb.141.4.943  1
1998 Vikstrom KL, Bohlmeyer T, Factor SM, Leinwand LA. Hypertrophy, pathology, and molecular markers of cardiac pathogenesis Circulation Research. 82: 773-778. PMID 9562436  1
1997 Nakao K, Minobe W, Roden R, Bristow MR, Leinwand LA. Myosin heavy chain gene expression in human heart failure Journal of Clinical Investigation. 100: 2362-2370. PMID 9410916  1
1997 Mayer DCG, Leinwand LA. Sarcomeric gene expression and contractility in myofibroblasts Journal of Cell Biology. 139: 1477-1484. PMID 9396753 DOI: 10.1083/jcb.139.6.1477  1
1997 Kass-Eisler A, Leinwand LA. DNA- and adenovirus-mediated gene transfer into cardiac muscle Methods in Cell Biology. 423-437. PMID 9379963  1
1997 Li K, Welikson RE, Vikstrom KL, Leinwand LA. Direct gene transfer into the mouse heart Journal of Molecular and Cellular Cardiology. 29: 1499-1504. PMID 9201634 DOI: 10.1006/jmcc.1997.0389  1
1997 Li K, Buvoli M, Welikson RE, Vikstrom KL, Leinwand LA. Advances in cardiovascular gene transfer Cardiologia (Rome, Italy). 42: 39-46. PMID 9118153  1
1997 Vikstrom KL, Seiler SH, Sohn RL, Strauss M, Weiss A, Welikson RE, Leinwand LA. The vertebrate myosin heavy chain: Genetics and assembly properties Cell Structure and Function. 22: 123-129. PMID 9113398  1
1997 Sohn RL, Vikstrom KL, Strauss M, Cohen C, Szent-Gyorgyi AG, Leinwand LA. A 29 residue region of the sarcomeric myosin rod is necessary for filament formation. Journal of Molecular Biology. 266: 317-30. PMID 9047366 DOI: 10.1006/jmbi.1996.0790  1
1997 Siri FM, Jelicks LA, Leinwand LA, Gardin JM. Gated magnetic resonance imaging of normal and hypertrophied murine hearts American Journal of Physiology - Heart and Circulatory Physiology. 41.  1
1997 Weinberger HD, Vikstrom KL, Knudson OA, Valdes-Cruz LM, Leinwand LA. Gender specific dilation in transgenic mice with hypertrophic cardiomyopathy: An echocardiographic study Journal of the American Society of Echocardiography. 10: 427.  1
1996 Weiss A, Leinwand LA. The mammalian myosin heavy chain gene family Annual Review of Cell and Developmental Biology. 12: 417-439. PMID 8970733 DOI: 10.1146/annurev.cellbio.12.1.417  1
1996 Vatner SF, Berk BC, Leinwand LA, Libby P, Schwartz K, Strauss HC. A second term for the editors: Status and goals for the review process Circulation Research. 79: 1-3. PMID 8925556  1
1996 Vikstrom KL, Factor SM, Leinwand LA. Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy Molecular Medicine. 2: 556-567. PMID 8898372  1
1996 Vikstrom KL, Leinwand LA. Contractile protein mutations and heart disease Current Opinion in Cell Biology. 8: 97-105. PMID 8791411 DOI: 10.1016/S0955-0674(96)80053-6  1
1996 Seiler SH, Fischman DA, Leinwand LA. Modulation of myosin filament organization by C-protein family members Molecular Biology of the Cell. 7: 113-127. PMID 8741844  1
1996 Edwards JG, Lyons GE, Micales BK, Malhotra A, Factor S, Leinwand LA. Cardiomyopathy in transgenic myf5 mice. Circulation Research. 78: 379-87. PMID 8593696  1
1995 Vikstrom KL, Factor SM, Leinwand LA. A murine model for hypertrophic cardiomyopathy Zeitschrift Fur Kardiologie. 84: 49-54. PMID 8585273  1
1995 Kass-Eisler A, Li K, Leinwand LA. Prospects for gene therapy with direct injection of polynucleotides Annals of the New York Academy of Sciences. 772: 232-240. PMID 8546398 DOI: 10.1111/j.1749-6632.1995.tb44749.x  1
1995 Gardin JM, Siri FM, Kitsis RN, Edwards JG, Leinwand LA. Echocardiographic assessment of left ventricular mass and systolic function in mice. Circulation Research. 76: 907-14. PMID 7729009  1
1995 Vikstrom KL, Leinwand LA. The molecular genetic basis of familial hypertrophic cardiomyopathy Heart Failure. 11: 5-14.  1
1995 Vikstrom KL, Leinwand LA. Transgenic mice: A tool for altering the cell and molecular biology of the heart Heart Failure. 11: 39-47.  1
1994 Sweeney HL, Straceski AJ, Leinwand LA, Tikunov BA, Faust L. Heterologous expression of a cardiomyopathic myosin that is defective in its actin interaction. The Journal of Biological Chemistry. 269: 1603-5. PMID 8294404  1
1994 Straceski AJ, Geisterfer-Lowrance A, Seidman CE, Seidman JG, Leinwand LA. Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy Proceedings of the National Academy of Sciences of the United States of America. 91: 589-593. PMID 8290568  1
1994 Buttrick PM, Kaplan M, Leinwand LA, Scheuer J. Alterations in gene expressin in the rat heart after chronic pathological and physiological loads Journal of Molecular and Cellular Cardiology. 26: 61-67. PMID 8196070 DOI: 10.1006/jmcc.1994.1008  1
1994 Sindhwani R, Ismail-Beigi F, Leinwand LA. Post-transcriptional regulation of rat α cardiac myosin heavy chain gene expression Journal of Biological Chemistry. 269: 3272-3276. PMID 8106364  1
1994 LeBlanc-Straceski JM, Fukui Y, Sohn RL, Spudich JA, Leinwand LA. Functional analysis of a cardiac myosin rod in Dictyostelium discoideum. Cell Motility and the Cytoskeleton. 27: 313-26. PMID 8069939 DOI: 10.1002/cm.970270404  1
1994 Weiss A, Mayer DC, Leinwand LA. Diversity of myosin-based motility: multiple genes and functions Society of General Physiologists Series. 49: 159-171. PMID 7939894  1
1994 Cho M, Hughes SM, Karsch-Mizrachi I, Travis M, Leinwand LA, Blau HM. Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception Journal of Cell Science. 107: 2361-2371. PMID 7531198  1
1993 Buttrick PM, Kaplan ML, Kitsis RN, Leinwand LA. Distinct behavior of cardiac myosin heavy chain gene constructs in vivo: Discordance with in vitro results Circulation Research. 72: 1211-1217. PMID 8495550  1
1993 Vikstrom KL, Rovner AS, Saez CG, Bravo-Zehnder M, Straceski AJ, Leinwand LA. Sarcomeric myosin heavy chain expressed in nonmuscle cells forms thick filaments in the presence of substoichiometric amounts of light chains. Cell Motility and the Cytoskeleton. 26: 192-204. PMID 8293476 DOI: 10.1002/cm.970260303  1
1993 Vatner SF, Leinwand LA, Libby P, Nadal-Ginard B, Schwartz K, Strauss HC. All manuscripts are not created equal: The expedited publication Circulation Research. 73: 1-2.  1
1992 Feghali R, Karsch-Mizrachi I, Leinwand LA, Kohtz DS. Four sarcomeric myosin heavy chain genes are expressed by human fetal skeletal muscle cells differentiating in culture Gene Expression. 2: 49-58. PMID 1617302  1
1992 Nadal-Ginard B, Leinwand LA, Libby P, Schwartz K, Strauss HC, Vatner SF. Cellular and molecular biology of the cardiovascular system Circulation Research. 71: 1-2. PMID 1606658  1
1992 Kitsis RN, Leinwand LA. Discordance between gene regulation in vitro and in vivo Gene Expression. 2: 313-318. PMID 1472867  1
1992 Kraft R, Kadyk L, Leinwand LA. Sequence organization of variant mouse 4.5 S RNA genes and pseudogenes Genomics. 12: 555-566. PMID 1373121 DOI: 10.1016/0888-7543(92)90448-2  1
1991 Leinwand LA, Leiden JM. Gene transfer into cardiac myocytes in vivo. Trends in Cardiovascular Medicine. 1: 271-6. PMID 21239293 DOI: 10.1016/1050-1738(91)90042-D  1
1991 Kitsis RN, Buttrick PM, Mcnally EM, Kaplan ML, Leinwand LA. Hormonal modulation of a gene injected into rat heart in vivo Proceedings of the National Academy of Sciences of the United States of America. 88: 4138-4142. PMID 2034660  1
1991 McNally EM, Bravo-Zehnder MM, Leinwand LA. Identification of sequences necessary for the association of cardiac myosin subunits Journal of Cell Biology. 113: 585-590. PMID 2016338  1
1991 Fishman GI, Moreno AP, Spray DC, Leinwand LA. Functional analysis of human cardiac gap junction channel mutants. Proceedings of the National Academy of Sciences of the United States of America. 88: 3525-9. PMID 1850831  1
1991 Fishman GI, Hertzberg EL, Spray DC, Leinwand LA. Expression of connexin43 in the developing rat heart. Circulation Research. 68: 782-7. PMID 1660362  1
1991 Fishman GI, Eddy RL, Shows TB, Rosenthal L, Leinwand LA. The human connexin gene family of gap junction proteins: Distinct chromosomal locations but similar structures Genomics. 10: 250-256. PMID 1646158 DOI: 10.1016/0888-7543(91)90507-B  1
1991 Leblanc JM, Leinwand LA. The diversity of myosin-based contractile systems in eukaryotic cells Integrative and Comparative Biology. 31: 514-521. DOI: 10.1093/icb/31.3.514  1
1990 Karsch-Mizrachi I, Feghali R, Shows TB, Leinwand LA. Generation of a full-length human perinatal myosin heavy-chain-encoding cDNA Gene. 89: 289-294. PMID 2373371 DOI: 10.1016/0378-1119(90)90020-R  1
1990 Rovner AS, McNally EM, Leinwand LA. Complete cDNA sequence of rat atrial myosin light chain 1: patterns of expression during development and with hypertension. Nucleic Acids Research. 18: 1581-6. PMID 2326197  1
1990 Tsika RW, Bahl JJ, Leinwand LA, Morkin E. Thyroid hormone regulates expression of a transfected human α-myosin heavy-chain fusion gene in fetal rat heart cells Proceedings of the National Academy of Sciences of the United States of America. 87: 379-383. PMID 2296592 DOI: 10.1073/pnas.87.1.379  1
1990 Goodwin EB, Leinwand LA, Szent-Györgyi AG. Regulation of scallop myosin by mutant regulatory light chains. Journal of Molecular Biology. 216: 85-93. PMID 2146399 DOI: 10.1016/S0022-2836(05)80062-2  1
1990 Saez CG, Myers JC, Shows TB, Leinwand LA. Human nonmuscle myosin heavy chain mRNA: generation of diversity through alternative polyadenylylation. Proceedings of the National Academy of Sciences of the United States of America. 87: 1164-8. PMID 1967836  1
1990 Fishman GI, Spray DC, Leinwand LA. Molecular characterization and functional expression of the human cardiac gap junction channel. The Journal of Cell Biology. 111: 589-98. PMID 1696265  1
1990 Buttrick PM, Kass A, Kitsis RN, Kaplan ML, Leinwand LA. Behavior of genes directly injected into the rat heart in vivo Circulation Research. 70: 193-198. PMID 1309314  1
1989 Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat beta cardiac myosin heavy chain. Nucleic Acids Research. 17: 7529-30. PMID 2798112 DOI: 10.1093/nar/17.18.7529  1
1989 Mcnally EM, Gianola KM, Leinwand LA. Complete nucleotide sequence of full length cDNA for rat α cardiac myosin hea chain Nucleic Acids Research. 17: 7527-7528. PMID 2798111 DOI: 10.1093/nar/17.18.7527  1
1989 Karsch-Mizrachi I, Travis M, Blau H, Leinwand LA. Expression and DNA sequence analysis of a human embryonic skeletal muscle mvosin heavy chain gene Nucleic Acids Research. 17: 6167-6179. PMID 2771643 DOI: 10.1093/nar/17.15.6167  1
1989 Mcnally EM, Buttrick PM, Leinwand LA. Ventricular myosin light chain 1 is developmentally regulated and does not change in hypertension Nucleic Acids Research. 17: 2753-2768. PMID 2717409 DOI: 10.1093/nar/17.7.2753  1
1989 Feghali R, Leinwand LA. Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain Journal of Cell Biology. 108: 1791-1797. PMID 2715179  1
1989 Leinwand LA, Sohn R, Frankel SA, Goodwin EB, McNally EM. Bacterial expression of eukaryotic contractile proteins Cell Motility and the Cytoskeleton. 14: 3-11. PMID 2684424  1
1989 McNally EM, Kraft R, Bravo-Zehnder M, Taylor DA, Leinwand LA. Full-length rat alpha and beta cardiac myosin heavy chain sequences. Comparisons suggest a molecular basis for functional differences. Journal of Molecular Biology. 210: 665-71. PMID 2614840 DOI: 10.1016/0022-2836(89)90141-1  1
1988 Heller DL, Gianola KM, Leinwand LA. A highly conserved mouse gene with a propensity to form pseudogenes in mammals Molecular and Cellular Biology. 8: 2797-2803. PMID 3405219  1
1988 Kraft R, Tardiff J, Krauter KS, Leinwand LA. Using mini-prep plasmid DNA for sequencing double stranded templates with sequenase(TM) Biotechniques. 6: 544-549. PMID 3273187  1
1988 McNally EM, Goodwin EB, Spudich JA, Leinwand LA. Coexpression and assembly of myosin heavy chain and myosin light chain in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 85: 7270-7273. PMID 3050991  1
1988 Deka N, Wong E, Matera AG, Kraft R, Leinwand LA, Schmid CW. Repetitive nucleotide sequence insertions into a novel calmodulin-related gene and its processed pseudogene. Gene. 71: 123-34. PMID 2463956 DOI: 10.1016/0378-1119(88)90084-4  1
1987 De Lozanne A, Berlot CH, Leinwand LA, Spudich JA. Expression in Escherichia coli of a functional Dictyostelium myosin tail fragment Journal of Cell Biology. 105: 2999-3005. PMID 3320060  1
1987 Saez LJ, Gianola KM, McNally EM, Feghali R, Eddy R, Shows TB, Leinwand LA. Human cardiac myosin heavy chain genes and their linkage in the genome Nucleic Acids Research. 15: 5443-5459. PMID 3037493  1
1987 Goodwin EB, Szent-Gyorgyi AG, Leinwand LA. Cloning and characterization of the scallop essential and regulatory myosin light chain cDNAs. The Journal of Biological Chemistry. 262: 11052-6. PMID 2440882  1
1987 Kraft R, Leinwand LA. Sequence of the complete P protein gene and part of the M protein gene from the histidine transport operon of Escherichia coli compared to that of Salmonella typhimurium Nucleic Acids Research. 15: 8568. DOI: 10.1093/nar/15.20.8568  1
1986 Warrick HM, De Lozanne A, Leinwand LA, Spudich JA. Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum Proceedings of the National Academy of Sciences of the United States of America. 83: 9433-9437. PMID 3540939  1
1986 Saez L, Leinwand LA. Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle Nucleic Acids Research. 14: 2951-2969. PMID 2421254 DOI: 10.1093/nar/14.7.2951  1
1985 DeLozanne A, Lewis M, Spudich JA, Leinwand LA. Cloning and characterization of a nonmuscle myosin heavy chain cDNA Proceedings of the National Academy of Sciences of the United States of America. 82: 6807-6810. PMID 3901008  1
1983 Leinwand LA, Fournier REK, Nadal Ginard B, Shows TB. Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: Localization on a single chromosome Science. 221: 766-769. PMID 6879174  1
1983 Leinwand LA, Saez L, McNally E, Nadal-Ginard B. Isolation and characterization of human myosin heavy chain genes Proceedings of the National Academy of Sciences of the United States of America. 80: 3716-3720. PMID 6304733  1
1982 Pease LR, Nathenson SG, Leinwand LA. Mapping class I gene sequences in the major histocompatibility complex Nature. 298: 382-385. PMID 6283386 DOI: 10.1038/298382a0  1
1982 Leinwand LA, Wydro RM, Nadal Ginard B. Small RNA molecules related to the Alu family of repetitive DNA sequences Molecular and Cellular Biology. 2: 1320-1330. PMID 6186902  1
1979 Kozak CA, Fournier REK, Leinwand LA, Ruddle FH. Assignment of the gene governing cellular ouabain resistance to Mus musculus chromosome 3 using human/mouse microcell hybrids Biochemical Genetics. 17: 23-34. PMID 454358 DOI: 10.1007/BF00484471  1
1978 Leinwand LA, Ruddle FH. Assignment of the gene for dipeptidase 2 to Mus musculus chromosome 18 by somatic cell hybridization Biochemical Genetics. 16: 477-484. PMID 736882 DOI: 10.1007/BF00484213  1
1978 Leinwand LA, Kozak CA, Ruddle FH. Assignment of the genes for triose phosphate isomerase to chromosome 6 and tripeptidase-1 to chromosome 10 in Mus musculus by somatic cell hybridization Somatic Cell Genetics. 4: 233-240. PMID 566475 DOI: 10.1007/BF01538987  1
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