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María Julieta Comin - Publications

Affiliations: 
2000-2004 Universidad de Buenos Aires, Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina 
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Elhalem E, Bellomo A, Cooke M, Scravaglieri A, Pearce LV, Peach ML, Gandolfi Donadío L, Kazanietz MG, Comin MJ. Design, Synthesis, and Characterization of Novel -1 Heterocyclic DAG-Lactones as PKC Activators. Journal of Medicinal Chemistry. PMID 34279947 DOI: 10.1021/acs.jmedchem.1c00739  0.77
2017 Elhalem E, Donadío LG, Zhou X, Lewin NE, Garcia LC, Lai CC, Kelley JA, Peach ML, Blumberg PM, Comin MJ. Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP. Bioorganic & Medicinal Chemistry. PMID 28392275 DOI: 10.1016/J.Bmc.2017.03.022  0.759
2017 Elhalem E, Donadío LG, Zhou X, Lewin NE, Garcia LC, Lai CC, Kelley JA, Peach ML, Blumberg PM, Comin MJ. Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP. Bioorganic & Medicinal Chemistry. PMID 28392275 DOI: 10.1016/J.Bmc.2017.03.022  0.759
2014 Garcia LC, Donadío LG, Mann E, Kolusheva S, Kedei N, Lewin NE, Hill CS, Kelsey JS, Yang J, Esch TE, Santos M, Peach ML, Kelley JA, Blumberg PM, Jelinek R, ... ... Comin MJ, et al. Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP. Bioorganic & Medicinal Chemistry. 22: 3123-40. PMID 24794745 DOI: 10.1016/J.Bmc.2014.04.024  0.587
2014 Garcia LC, Donadío LG, Mann E, Kolusheva S, Kedei N, Lewin NE, Hill CS, Kelsey JS, Yang J, Esch TE, Santos M, Peach ML, Kelley JA, Blumberg PM, Jelinek R, ... ... Comin MJ, et al. Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP. Bioorganic & Medicinal Chemistry. 22: 3123-40. PMID 24794745 DOI: 10.1016/J.Bmc.2014.04.024  0.587
2010 Raifman O, Kolusheva S, Comin MJ, Kedei N, Lewin NE, Blumberg PM, Marquez VE, Jelinek R. Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities. The Febs Journal. 277: 233-43. PMID 19961537 DOI: 10.1111/J.1742-4658.2009.07477.X  0.525
2010 Comin MJ, Pujol CA, Damonte EB, Rodriguez JB. ChemInform Abstract: Synthesis of C-5′-nor-Dideoxycarbanucleosides Structurally Related to Neplanocin C. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200010208  0.546
2009 Comin MJ, Czifra G, Kedei N, Telek A, Lewin NE, Kolusheva S, Velasquez JF, Kobylarz R, Jelinek R, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths. Journal of Medicinal Chemistry. 52: 3274-83. PMID 19379015 DOI: 10.1021/Jm900186M  0.523
2009 Comin MJ, Czifra G, Kedei N, Telek A, Lewin NE, Kolusheva S, Velasquez JF, Kobylarz R, Jelinek R, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths. Journal of Medicinal Chemistry. 52: 3274-83. PMID 19379015 DOI: 10.1021/Jm900186M  0.523
2008 Philosof-Mazor L, Volinsky R, Comin MJ, Lewin NE, Kedei N, Blumberg PM, Marquez VE, Jelinek R. Self-assembly and lipid interactions of diacylglycerol lactone derivatives studied at the air/water interface. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 11043-52. PMID 18788772 DOI: 10.1021/La802204N  0.48
2008 Philosof-Mazor L, Volinsky R, Comin MJ, Lewin NE, Kedei N, Blumberg PM, Marquez VE, Jelinek R. Self-assembly and lipid interactions of diacylglycerol lactone derivatives studied at the air/water interface. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 11043-52. PMID 18788772 DOI: 10.1021/La802204N  0.48
2008 Comin MJ, Vu BC, Boyer PL, Liao C, Hughes SH, Marquez VE. D-(+)-iso-methanocarbathymidine: a high-affinity substrate for herpes simplex virus 1 thymidine kinase. Chemmedchem. 3: 1129-34. PMID 18399509 DOI: 10.1002/cmdc.200800027  0.51
2008 Comin MJ, Vu BC, Boyer PL, Liao C, Hughes SH, Marquez VE. D-(+)-iso-methanocarbathymidine: a high-affinity substrate for herpes simplex virus 1 thymidine kinase. Chemmedchem. 3: 1129-34. PMID 18399509 DOI: 10.1002/cmdc.200800027  0.51
2007 Marquez VE, Comin MJ. Rearranging the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve binding recognition by kinases. Nucleosides, Nucleotides & Nucleic Acids. 26: 585-8. PMID 18066860 DOI: 10.1080/15257770701490175  0.305
2007 Marquez VE, Comin MJ. Rearranging the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve binding recognition by kinases. Nucleosides, Nucleotides & Nucleic Acids. 26: 585-8. PMID 18066860 DOI: 10.1080/15257770701490175  0.566
2007 Comin MJ, Agbaria R, Ben-Kasus T, Huleihel M, Liao C, Sun G, Nicklaus MC, Deschamps JR, Parrish DA, Marquez VE. Sculpting the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve recognition by herpes thymidine kinase. Journal of the American Chemical Society. 129: 6216-22. PMID 17451242 DOI: 10.1021/ja0688732  0.566
2007 Comin MJ, Agbaria R, Ben-Kasus T, Huleihel M, Liao C, Sun G, Nicklaus MC, Deschamps JR, Parrish DA, Marquez VE. Sculpting the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve recognition by herpes thymidine kinase. Journal of the American Chemical Society. 129: 6216-22. PMID 17451242 DOI: 10.1021/ja0688732  0.566
2006 Comin MJ, Parrish DA, Deschamps JR, Marquez VE. Synthesis of bicyclo[3.1.0]hexanes functionalized at the tip of the cyclopropane ring. Application to the synthesis of carbocyclic nucleosides. Organic Letters. 8: 705-8. PMID 16468747 DOI: 10.1021/ol052886n  0.562
2006 Comin MJ, Parrish DA, Deschamps JR, Marquez VE. Synthesis of bicyclo[3.1.0]hexanes functionalized at the tip of the cyclopropane ring. Application to the synthesis of carbocyclic nucleosides. Organic Letters. 8: 705-8. PMID 16468747 DOI: 10.1021/ol052886n  0.562
2006 Elhalem E, Comin MJ, Rodriguez JB. Synthesis of Conformationally Locked Carbocyclic Nucleosides Built on a Thiabicyclo[3.1.0]hexane System as a Pseudosugar Surrogate European Journal of Organic Chemistry. 2006: 4473-4482. DOI: 10.1002/EJOC.200600488  0.744
2005 Marquez VE, Choi Y, Comin MJ, Russ P, George C, Huleihel M, Ben-Kasus T, Agbaria R. Understanding how the herpes thymidine kinase orchestrates optimal sugar and nucleobase conformations to accommodate its substrate at the active site: a chemical approach. Journal of the American Chemical Society. 127: 15145-50. PMID 16248655 DOI: 10.1021/Ja053789S  0.543
2005 Elhalem E, Comin MJ, Leitofuter J, García-Liñares G, Rodriguez JB. Synthetic studies toward the preparation of (4R,5R)-(−)-3-[(benzyloxy)methyl]-4,5-O-isopropylidene-cyclopenten-2-one: an important synthetic intermediate for carbanucleosides Tetrahedron: Asymmetry. 16: 425-431. DOI: 10.1016/J.TETASY.2004.11.069  0.704
2004 Gao ZG, Jeong LS, Moon HR, Kim HO, Choi WJ, Shin DH, Elhalem E, Comin MJ, Melman N, Mamedova L, Gross AS, Rodriguez JB, Jacobson KA. Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety. Biochemical Pharmacology. 67: 893-901. PMID 15104242 DOI: 10.1016/J.Bcp.2003.10.006  0.716
2004 Comin MJ, Elhalem E, Rodriguez JB. Cerium ammonium nitrate: a new catalyst for regioselective protection of glycols Tetrahedron. 60: 11851-11860. DOI: 10.1016/J.TET.2004.09.097  0.705
2003 Choi Y, George C, Comin MJ, Barchi JJ, Kim HS, Jacobson KA, Balzarini J, Mitsuya H, Boyer PL, Hughes SH, Marquez VE. A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Journal of Medicinal Chemistry. 46: 3292-9. PMID 12852759 DOI: 10.1021/Jm030116G  0.475
2003 Choi Y, George C, Comin MJ, Barchi JJ, Kim HS, Jacobson KA, Balzarini J, Mitsuya H, Boyer PL, Hughes SH, Marquez VE. A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Journal of Medicinal Chemistry. 46: 3292-9. PMID 12852759 DOI: 10.1021/Jm030116G  0.475
2003 Rodríguez JB, Comin MJ. New progresses in the enantioselective synthesis and biological properties of carbocyclic nucleosides. Mini Reviews in Medicinal Chemistry. 3: 95-114. PMID 12570843 DOI: 10.2174/1389557033405331  0.59
2003 Rodríguez JB, Comin MJ. New progresses in the enantioselective synthesis and biological properties of carbocyclic nucleosides. Mini Reviews in Medicinal Chemistry. 3: 95-114. PMID 12570843 DOI: 10.2174/1389557033405331  0.59
2003 Comin MJ, Rodriguez JB, Russ P, Marquez VE. Synthesis of conformationally locked carbocyclic nucleosides built on an oxabicyclo[3.1.0]hexane system Tetrahedron. 59: 295-301. DOI: 10.1016/S0040-4020(02)01528-4  0.594
2003 Rodriguez JB, Comin MJ. New Progresses in the Enantioselective Synthesis and Biological Properties of Carbocyclic Nucleosides Cheminform. 34. DOI: 10.1002/CHIN.200336234  0.577
2002 Comin MJ, Leitofuter J, Rodrı́guez JB. Enantioselective synthesis of (+)-neplanocin F Tetrahedron. 58: 3129-3136. DOI: 10.1016/S0040-4020(02)00287-9  0.507
2000 Comin MJ, Rodriguez JB. ChemInform Abstract: First Synthesis of (-)-Neplanocin C. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200042214  0.56
1999 Comin MJ, Pujol CA, Damonte EB, Rodriguez JB. Synthesis of C-5'-nor-dideoxycarbanucleosides structurally related to neplanocin C. Nucleosides & Nucleotides. 18: 2219-31. PMID 10616727 DOI: 10.1080/07328319908044877  0.333
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