| Year |
Citation |
Score |
| 2008 |
Barchi JJ, Karki RG, Nicklaus MC, Siddiqui MA, George C, Mikhailopulo IA, Marquez VE. Comprehensive structural studies of 2′,3′-difluorinated nucleosides: Comparison of theory, solution, and solid state Journal of the American Chemical Society. 130: 9048-9057. PMID 18558684 DOI: 10.1021/Ja800964G |
0.368 |
|
| 2007 |
Khanolkar AD, Lu D, Ibrahim M, Duclos RI, Thakur GA, Malan TP, Porreca F, Veerappan V, Tian X, George C, Parrish DA, Papahatjis DP, Makriyannis A. Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity. Journal of Medicinal Chemistry. 50: 6493-500. PMID 18038967 DOI: 10.1021/Jm070441U |
0.348 |
|
| 2005 |
Marquez VE, Choi Y, Comin MJ, Russ P, George C, Huleihel M, Ben-Kasus T, Agbaria R. Understanding how the herpes thymidine kinase orchestrates optimal sugar and nucleobase conformations to accommodate its substrate at the active site: a chemical approach. Journal of the American Chemical Society. 127: 15145-50. PMID 16248655 DOI: 10.1021/Ja053789S |
0.323 |
|
| 2005 |
Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, Hurst DP, Reggio PH, Deschamps JR, Parrish DA, George C, Järbe TU, Lamb RJ, Makriyannis A. Adamantyl cannabinoids: a novel class of cannabinergic ligands. Journal of Medicinal Chemistry. 48: 4576-85. PMID 15999995 DOI: 10.1021/Jm058175C |
0.365 |
|
| 2005 |
Crisma M, Deschamps JR, George C, Flippen-Anderson JL, Kaptein B, Broxterman QB, Moretto A, Oancea S, Jost M, Formaggio F, Toniolo C. A topographically and conformationally constrained, spin-labeled, alpha-amino acid: crystallographic characterization in peptides. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 564-79. PMID 15885116 DOI: 10.1111/J.1399-3011.2005.00258.X |
0.342 |
|
| 2004 |
Saavedra JE, Bohle DS, Smith KN, George C, Deschamps JR, Parrish D, Ivanic J, Wang YN, Citro ML, Keefer LK. Chemistry of the diazeniumdiolates. O- versus N-alkylation of the RNH[N(O)NO](-) ion. Journal of the American Chemical Society. 126: 12880-7. PMID 15469285 DOI: 10.1021/Ja031538I |
0.315 |
|
| 2004 |
Siddiqui MA, Hughes SH, Boyer PL, Mitsuya H, Van QN, George C, Sarafinanos SG, Marquez VE. A 4'-C-ethynyl-2',3'-dideoxynucleoside analogue highlights the role of the 3'-OH in anti-HIV active 4'-C-ethynyl-2'-deoxy nucleosides. Journal of Medicinal Chemistry. 47: 5041-8. PMID 15456247 DOI: 10.1021/Jm049550O |
0.302 |
|
| 2004 |
Hashimoto A, Przybyl AK, Linders JT, Kodato S, Tian X, Deschamps JR, George C, Flippen-Anderson JL, Jacobson AE, Rice KC. Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans. The Journal of Organic Chemistry. 69: 5322-7. PMID 15287777 DOI: 10.1021/Jo040159K |
0.393 |
|
| 2004 |
Butcher RJ, George C, Purdy AP. Tetra‐μ‐chloro‐chloro(N,N,N′,N′‐tetramethylethane‐1,2‐diamine)(1,1,3‐trimethyl‐2‐imidazolium)dicopper(I)copper(II) Acta Crystallographica Section E: Crystallographic Communications. 60. DOI: 10.1107/S1600536803027752 |
0.321 |
|
| 2003 |
Choi Y, Sun G, George C, Nicklaus MC, Kelley JA, Marquez VE. Synthesis and conformational analysis of a locked analogue of carbovir built on a bicyclo[3.1.0]hex-2-enyl template. Nucleosides, Nucleotides & Nucleic Acids. 22: 2077-91. PMID 14714758 DOI: 10.1081/Ncn-120026631 |
0.332 |
|
| 2003 |
Kim IJ, Ullrich T, Janetka JW, Furness MS, Jacobson AE, Rothman RB, Dersch CM, Flippen-Anderson JL, George C, Rice KC. Diaryldimethylpiperazine ligands with μ- and δ-opioid receptor affinity: Synthesis of (+)-4-[(αR)-α -(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide and (-)-4-[(αR)-α -(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl] -N-ethyl-N-phenylbenzamide Bioorganic and Medicinal Chemistry. 11: 4761-4768. PMID 14556791 DOI: 10.1016/S0968-0896(03)00496-6 |
0.359 |
|
| 2003 |
Choi Y, George C, Comin MJ, Barchi JJ, Kim HS, Jacobson KA, Balzarini J, Mitsuya H, Boyer PL, Hughes SH, Marquez VE. A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Journal of Medicinal Chemistry. 46: 3292-9. PMID 12852759 DOI: 10.1021/Jm030116G |
0.301 |
|
| 2003 |
Kolhatkar RB, Ghorai SK, George C, Reith ME, Dutta AK. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine. Journal of Medicinal Chemistry. 46: 2205-15. PMID 12747792 DOI: 10.1021/Jm020561W |
0.398 |
|
| 2003 |
Ghorai SK, Cook C, Davis M, Venkataraman SK, George C, Beardsley PM, Reith ME, Dutta AK. High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo. Journal of Medicinal Chemistry. 46: 1220-8. PMID 12646032 DOI: 10.1021/Jm020275K |
0.31 |
|
| 2003 |
Deschamps JR, George C. Advances in X-ray crystallography Trac Trends in Analytical Chemistry. 22: 561-564. DOI: 10.1016/S0165-9936(03)00902-6 |
0.307 |
|
| 2003 |
Wei ZL, George C, Kozikowski AP. Synthesis of 5-endo-, 5-exo-, 6-endo- and 6-exo-hydroxylated analogues of epibatidine Tetrahedron Letters. 44: 3847-3850. DOI: 10.1016/S0040-4039(03)00737-8 |
0.312 |
|
| 2003 |
Wang X, Yao Z, Liu H, Zhang M, Yang D, George C, Burke TR. Synthesis of a phosphotyrosyl analogue having χ1, χ2 and φ angles constrained to values observed for an SH2 domain-bound phosphotyrosyl residue Tetrahedron. 59: 6087-6093. DOI: 10.1016/S0040-4020(03)00978-5 |
0.329 |
|
| 2003 |
Prisinzano T, Hsin L, Folk JE, Flippen-Anderson JL, George C, Jacobson AE, Rice KC. A concise synthesis of (S)-(+)-1-(4-{2-[bis-(4-fluorophenyl)methoxy]-ethyl}piperazin-1-yl)-2-phenylpropan-2-ol dimaleate Tetrahedron: Asymmetry. 14: 3285-3289. DOI: 10.1016/J.Tetasy.2003.05.001 |
0.347 |
|
| 2003 |
Francisco MEY, Burgess JP, George C, Bailey GS, Gilliam AF, Seltzman HH, Thomas BF. Structure elucidation of a novel ring-constrained biaryl pyrazole CB 1 cannabinoid receptor antagonist Magnetic Resonance in Chemistry. 41: 265-268. DOI: 10.1002/Mrc.1174 |
0.395 |
|
| 2003 |
Linders J, Mirsadeghi S, Flippen-Anderson J, George C, Jacobson A, Rice K. Probes for Narcotic Receptor Mediated Phenomena Helvetica Chimica Acta. 86: 484-493. DOI: 10.1002/Hlca.200390048 |
0.359 |
|
| 2002 |
Deschamps JR, Flippen-Anderson JL, George C. X-ray studies on ligands. Biopolymers. 66: 287-93. PMID 12539257 DOI: 10.1002/Bip.10308 |
0.302 |
|
| 2002 |
Bryant SD, George C, Flippen-Anderson JL, Deschamps JR, Salvadori S, Balboni G, Guerrini R, Lazarus LH. Crystal structures of dipeptides containing the Dmt-Tic pharmacophore Journal of Medicinal Chemistry. 45: 5506-5513. PMID 12459018 DOI: 10.1021/Jm020330P |
0.406 |
|
| 2002 |
Hashimoto A, Jacobson AE, Rothman RB, Dersch CM, George C, Flippen-Anderson JL, Rice KC. Probes for narcotic receptor mediated phenomena. Part 28: new opioid antagonists from enantiomeric analogues of 5-(3-hydroxyphenyl)-N-phenylethylmorphan. Bioorganic & Medicinal Chemistry. 10: 3319-29. PMID 12150879 DOI: 10.1016/S0968-0896(02)00219-5 |
0.326 |
|
| 2002 |
Deschamps JR, George C, Flippen-Anderson JL. (1R)-2-[(3R,4S)-3-Methyl-4-(N-phenyl-N-propionylamino)piperidin-1-yl]-1-phenylethyl p-bromobenzoate and N-[(3R,4S)-1-[(2S)-2-(4-bromophenyl)-2-hydroxyethyl]-3-methyl-piperidin-4-yl]-N-phenylacrylamide. Acta Crystallographica. Section C, Crystal Structure Communications. 58: o362-4. PMID 12050443 DOI: 10.1107/S0108270102006443 |
0.377 |
|
| 2002 |
Choi Y, George C, Strazewski P, Marquez VE. Synthesis of a conformationally locked version of puromycin amino nucleoside. Organic Letters. 4: 589-92. PMID 11843598 DOI: 10.1021/Ol010288C |
0.338 |
|
| 2002 |
Gilardi R, George C, Evans R. cis-2,4-Dinitro-6,8-dipropionyl-1H,5H-2,4,6,8-tetraazabicyclo[3.3.0]octane, a precursor of the energetic compound `bicyclo-HMX' Acta Crystallographica Section E Structure Reports Online. 58: o969-o971. DOI: 10.1107/S1600536802013570 |
0.343 |
|
| 2001 |
Keefer LK, Flippen-Anderson JL, George C, Shanklin AP, Dunams TM, Christodoulou D, Saavedra JE, Sagan ES, Bohle DS. Chemistry of the diazeniumdiolates. I. Structural and spectral characteristics of the [N(O)NO]- functional group. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 5: 377-94. PMID 11485376 DOI: 10.1006/Niox.2001.0359 |
0.339 |
|
| 2001 |
Meltzer PC, Wang B, Chen Z, Blundell P, Jayaraman M, Gonzalez MD, George C, Madras BK. Synthesis of 6- and 7- hydroxy-8-azabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters. Journal of Medicinal Chemistry. 44: 2619-35. PMID 11472216 DOI: 10.1021/Jm0101242 |
0.317 |
|
| 2001 |
Newman AH, Robarge MJ, Howard IM, Wittkopp SL, George C, Kopajtic T, Izenwasser S, Katz JL. Structure-activity relationships at monoamine transporters and muscarinic receptors for N-substituted-3alpha-(3'-chloro-, 4'-chloro-, and 4',4''-dichloro-substituted-diphenyl)methoxytropanes. Journal of Medicinal Chemistry. 44: 633-40. PMID 11170654 DOI: 10.1021/Jm000417F |
0.361 |
|
| 2001 |
Deschamps JR, Flippen-Anderson JL, Brine GA, Hayes JP, George C. Boc-tyrosyl-D-alanyl-glycyl-N-methyl-phenylalanyl-O-methyl-methionine hydrate: a protected analog of metkephamid Acta Crystallographica Section E Structure Reports Online. 58: o13-o15. DOI: 10.1107/S1600536801020475 |
0.335 |
|
| 2001 |
Ferrer JR, Lahti PM, George C, Oliete P, Julier M, Palacio F. Role of hydrogen bonds in benzimidazole-based organic magnetic materials: Crystal scaffolding or exchange linkers? Chemistry of Materials. 13: 2447-2454. DOI: 10.1021/Cm010322H |
0.304 |
|
| 2000 |
Froimowitz M, Wu KM, Moussa A, Haidar RM, Jurayj J, George C, Gardner EL. Slow-onset, long-duration 3-(3′,4′-dichlorophenyl)-1-indanamine monoamine reuptake blockers as potential medications to treat cocaine abuse Journal of Medicinal Chemistry. 43: 4981-4992. PMID 11150168 DOI: 10.1021/Jm000201D |
0.338 |
|
| 2000 |
Kozikowski AP, Tückmantel W, George C. Studies in polyphenol chemistry and bioactivity. 2. Establishment of interflavan linkage regio- and stereochemistry by oxidative degradation of an O-alkylated derivative of procyanidin B2 to (R)-(-)-2,4-diphenylbutyric acid Journal of Organic Chemistry. 65: 5371-5381. PMID 10993368 DOI: 10.1021/Jo000485+ |
0.381 |
|
| 2000 |
Hrabie JA, Arnold EV, Citro ML, George C, Keefer LK. Reaction of nitric oxide at the beta-carbon of enamines. A new method of preparing compounds containing the diazeniumdiolate functional group. The Journal of Organic Chemistry. 65: 5745-51. PMID 10970319 DOI: 10.1021/Jo000600G |
0.332 |
|
| 2000 |
Hoepping A, Johnson KM, George C, Flippen-Anderson J, Kozikowski AP. Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter. Journal of Medicinal Chemistry. 43: 2064-71. PMID 10821718 DOI: 10.1021/Jm0001121 |
0.372 |
|
| 2000 |
Robarge MJ, Agoston GE, Izenwasser S, Kopajtic T, George C, Katz JL, Newman AH. Highly selective chiral N-substituted 3alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues for the dopamine transporter: synthesis and comparative molecular field analysis. Journal of Medicinal Chemistry. 43: 1085-93. PMID 10737741 DOI: 10.1021/Jm990265S |
0.319 |
|
| 2000 |
Froimowitz M, Wu KM, Rodrigo J, George C. Conformational preferences of the potent dopamine reuptake blocker BTCP and its analogs and their incorporation into a pharmacophore model. Journal of Computer-Aided Molecular Design. 14: 135-46. PMID 10721502 DOI: 10.1023/A:1008144707255 |
0.355 |
|
| 2000 |
Deschamps JR, Flippen-Anderson JL, George C. 2-[N-(tert-Butoxycarbonyl)tyrosyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid nitromethane solvate Acta Crystallographica Section E Structure Reports Online. 57: o87-o90. DOI: 10.1107/S1600536800020109 |
0.352 |
|
| 2000 |
Hoepping A, George C, Flippen-Anderson J, Kozikowski AP. Radical cyclization strategies for the formation of ring constrained tricyclic tropane analogues Tetrahedron Letters. 41: 7427-7432. DOI: 10.1016/S0040-4039(00)01288-0 |
0.318 |
|
| 1999 |
Marquez VE, Russ P, Alonso R, Siddiqui MA, Shin K, George C, Nicklaus MC, Dai F, Ford H. Conformationally restricted nucleosides. The reaction of adenosine deaminase with substrates built on a bicyclo[3.1.0]hexane template. Nucleosides, Nucleotides & Nucleic Acids. 18: 521-530. PMID 10432643 DOI: 10.1080/15257779908041487 |
0.306 |
|
| 1999 |
Monaco V, Formaggio F, Crisma M, Toniolo C, Hanson P, Millhauser G, George C, Deschamps JR, Flippen-Anderson JL. Determining the occurrence of a 310-helix and an α-helix in two different segments of a lipopeptaibol antibiotic using TOAC, a nitroxide spin-labeled C(α)-tetrasubstituted α-aminoacid Bioorganic and Medicinal Chemistry. 7: 119-131. PMID 10199662 DOI: 10.1016/S0968-0896(98)00220-X |
0.335 |
|
| 1999 |
Marquez V, Russ P, Alonso R, Siddiqui M, Hernandez S, George C, Nicklaus M, Dai F, Ford, Jr. H. Synthesis of Conformationally Restricted Carbocyclic Nucleosides: The Role of the O(4′)-Atom in the Key Hydration Step of Adenosine Deaminase Helvetica Chimica Acta. 82: 2119-2129. DOI: 10.1002/(Sici)1522-2675(19991215)82:12<2119::Aid-Hlca2119>3.0.Co;2-Y |
0.338 |
|
| 1998 |
Froimowitz M, George C. Conformational analysis and a crystal structure of bupropion, an antidepressant with dopamine reuptake blocking activity. Journal of Chemical Information and Computer Sciences. 38: 506-10. PMID 9611786 DOI: 10.1021/Ci980401M |
0.345 |
|
| 1998 |
Kozikowski AP, Araldi GL, Boja J, Meil WM, Johnson KM, Flippen-Anderson JL, George C, Saiah E. Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton. Journal of Medicinal Chemistry. 41: 1962-9. PMID 9599245 DOI: 10.1021/Jm980028+ |
0.357 |
|
| 1998 |
Southan GJ, Srinivasan A, Keefer LK, George C, Fales HM. N-Nitrosated N-hydroxyguanidines are nitric oxide-releasing diazeniumdiolates Chemical Communications. 1191-1192. DOI: 10.1039/A801543K |
0.301 |
|
| 1998 |
Froimowitz M, Wu K, George C, VanDerveer D, Shi Q, Deutsch HM. Crystal Structures of Analogs of threo-Methylphenidate Structural Chemistry. 9: 295-303. DOI: 10.1023/A:1022435131188 |
0.338 |
|
| 1998 |
Deschamps JR, George C, Flippen-Anderson JL, DeMilo AB, Bordás B. Journal of Chemical Crystallography. 28: 453-459. DOI: 10.1023/A:1021768622056 |
0.326 |
|
| 1998 |
Glaser R, Adin I, Shiftan D, Shi Q, Deutsch HM, George C, Wu K, Froimowitz M. Solution and Solid-State Conformational and Structural Analysis of theN-Methyl Derivatives of (±)-threo-Methylphenidate, (±)-erythro-Methylphenidate, and (±)-threo-p-Methyl-methylphenidate Hydrochloride Salts The Journal of Organic Chemistry. 63: 1785-1794. DOI: 10.1021/Jo971063B |
0.346 |
|
| 1998 |
Smith MP, George C, Kozikowski AP. The synthesis of tricyclic cocaine analogs via the 1,3-dipolar cycloaddition of oxidopyridinium betaines Tetrahedron Letters. 39: 197-200. DOI: 10.1016/S0040-4039(97)10524-X |
0.342 |
|
| 1998 |
Deschamps JR, George C, Flippen-Anderson JL. The relationship between structure and activity among opioid peptides Letters in Peptide Science. 5: 337-340. DOI: 10.1007/Bf02443482 |
0.322 |
|
| 1997 |
Agoston GE, Wu JH, Izenwasser S, George C, Katz J, Kline RH, Newman AH. Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine transporter. Journal of Medicinal Chemistry. 40: 4329-39. PMID 9435902 DOI: 10.1021/Jm970525A |
0.345 |
|
| 1997 |
Flippen-Anderson JL, Deschamps JR, George C, Reddy PA, Lewin AH, Brine GA, Sheldrick G, Nikiforovich G. X-ray structure of Tyr-D-Tic-Phe-Phe-NH2 (D-TIPP-NH2), a highly potent mu-receptor selective opioid agonist. Comparison with proposed model structures. The Journal of Peptide Research : Official Journal of the American Peptide Society. 49: 384-93. PMID 9211219 DOI: 10.1111/J.1399-3011.1997.Tb00890.X |
0.324 |
|
| 1997 |
Marquez VE, Ezzitouni A, Siddiqui MA, Russ P, Ikeda H, George C. Conformational Analysis of Nucleosides Constructed on a Bicyclo[3.1.0]hexane Template. Structure-Antiviral Activity Analysis for the Northern and Southern Hemispheres of the Pseudorotational Cycle Nucleosides and Nucleotides. 16: 1431-1434. DOI: 10.1080/07328319708006199 |
0.301 |
|
| 1997 |
Gilardi R, Flippen-Anderson J, George C, Butcher RJ. A New Class of Flexible Energetic Salts: The Crystal Structures of the Ammonium, Lithium, Potassium, and Cesium Salts of Dinitramide Journal of the American Chemical Society. 119: 9411-9416. DOI: 10.1021/Ja9709280 |
0.351 |
|
| 1997 |
Froimowitz M, Deutsh HM, Shi Q, Wu K, Glaser R, Adin I, George C, Schweri MM. Further evidence for a dopamine reuptake pharmacophore. The effect of N-methylation on Threo-methylphenidate and its analogs Bioorganic & Medicinal Chemistry Letters. 7: 1213-1218. DOI: 10.1016/S0960-894X(97)00193-5 |
0.33 |
|
| 1997 |
Crisma M, Monaco V, Formaggio F, Toniolo C, George C, Flippen-Anderson JL. Crystallographic structure of a helical lipopeptaibol antibiotic analogue Letters in Peptide Science. 4: 213-218. DOI: 10.1007/Bf02442878 |
0.358 |
|
| 1996 |
Deschamps JR, George C, Flippen-Anderson JL. [D-Ala2,D-Leu5]-enkephalin hydrochloride. Acta Crystallographica. Section C, Crystal Structure Communications. 52: 1583-5. PMID 8766899 DOI: 10.1107/S0108270196000534 |
0.319 |
|
| 1996 |
Flippen-Anderson JL, George C, Valle G, Valente E, Bianco A, Formaggio F, Crisma M, Toniolo C. Crystallographic characterization of geometry and conformation of TOAC, a nitroxide spin-labelled C alpha,alpha-disubstituted glycine, in simple derivatives and model peptides. International Journal of Peptide and Protein Research. 47: 231-8. PMID 8738647 DOI: 10.1111/J.1399-3011.1996.Tb01350.X |
0.338 |
|
| 1996 |
Lee J, Sharma R, Wang S, Milne GW, Lewin NE, Szallasi Z, Blumberg PM, George C, Marquez VE. Conformationally constrained analogues of diacylglycerol. 12. Ultrapotent protein kinase C ligands based on a chiral 4,4-disubstituted heptono-1,4-lactone template. Journal of Medicinal Chemistry. 39: 36-45. PMID 8568825 DOI: 10.1021/Jm950278F |
0.35 |
|
| 1996 |
Deschamps JR, George C, Flippen-Anderson JL. Structural studies of opioid peptides: a review of recent progress in x-ray diffraction studies. Biopolymers. 40: 121-39. PMID 8541444 DOI: 10.1002/Bip.360400102 |
0.306 |
|
| 1996 |
Deschamps JR, George C, Gilardi RD, Gagnon JL, Zajac Jnr WW. cis-1,5-Dimethyl-2,4-dinitro-2,4-diazabicyclo[3.2.0]heptan-3-one and cis-1,5-Dimethyl-2,4-dinitro-2,4-diazabicyclo[3.1.0]hexan-3-one Acta Crystallographica Section C Crystal Structure Communications. 52: 993-995. DOI: 10.1107/S010827019501393X |
0.358 |
|
| 1996 |
Siddiqui MA, Ford H, George C, Marquez VE. Synthesis, Conformational Analysis, and Biological Activity of a Rigid Carbocyclic Analogue of 2′-Deoxy Aristeromycin Built on a Bicyclo[3.1.0]hexane Template Nucleosides and Nucleotides. 15: 235-250. DOI: 10.1080/07328319608002382 |
0.384 |
|
| 1996 |
Collins N, Flippen-Anderson JL, Haaseth RC, Deschamps JR, George C, Kövér K, Hruby VJ. Conformational Determinants of Agonist versus Antagonist Properties of [d-Pen2,d-Pen5]Enkephalin (DPDPE) Analogs at Opioid Receptors. Comparison of X-ray Crystallographic Structure, Solution1H NMR Data, and Molecular Dynamic Simulations of [l-Ala3]DPDPE and [d-Ala3]DPDPE Journal of the American Chemical Society. 118: 2143-2152. DOI: 10.1021/Ja9531081 |
0.341 |
|
| 1996 |
Butcher RJ, Gilardi RD, George C, Flippen-Anderson J. Distortions in nitramine substituted cubanes: The structures of N,N′-dinitro-1,4-diaminocubane, N,N′-dinitro-N,N′-(2-pyridyl)-1,4-diaminocubane, and 1,2,4,7-tetrakis(N-methoxycarbonylnitramino)cubane Journal of Chemical Crystallography. 26: 381-388. DOI: 10.1007/Bf01665815 |
0.353 |
|
| 1995 |
Newman AH, Kline RH, Allen AC, Izenwasser S, George C, Katz JL. Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors. Journal of Medicinal Chemistry. 38: 3933-40. PMID 7562926 DOI: 10.1021/Jm00020A006 |
0.303 |
|
| 1995 |
Burke TR, Barchi JJ, George C, Wolf G, Shoelson SE, Yan X. Conformationally constrained phosphotyrosyl mimetics designed as monomeric Src homology 2 domain inhibitors. Journal of Medicinal Chemistry. 38: 1386-96. PMID 7537333 DOI: 10.1021/Jm00008A017 |
0.307 |
|
| 1995 |
George C, Gilardi RD, Zajac Jnr WW, Buzby JH, Walters TR. 3,7-Dinitronoradamantane, C9H12N2O4, and 3,7,9-Trinitronoradamantane, C9H11N3O6 Acta Crystallographica Section C Crystal Structure Communications. 51: 703-706. DOI: 10.1107/S0108270194011868 |
0.322 |
|
| 1995 |
Forohar F, Dave PR, Axenrod T, Bedford CD, Gilardi R, George C. SYNTHESIS OF ETHYLENEDINITRAMINE DERIVATIVES OF FLUOROCYCLOTRIPHOSPHAZENES Phosphorus, Sulfur, and Silicon and the Related Elements. 101: 161-166. DOI: 10.1080/10426509508042512 |
0.401 |
|
| 1994 |
Flippen-Anderson JL, George C, Deschamps JR. Methyl N,N-diallyl-O-tert-butyltyrosyl-alpha-aminoisobutyrl-alpha- aminoisobutyrate, C28H43N3O5. Acta Crystallographica. Section C, Crystal Structure Communications. 50: 1095-7. PMID 8074811 DOI: 10.1107/S0108270193012387 |
0.332 |
|
| 1994 |
Pizzonero M, L. Flippen-Anderson J, George C, M. Bertha C, C. Rice K. X-Ray Crystal Structures of Potent Receptor Ligands: Etonitazene, cis-(+)-3-Methylfentanyl, Etorphine, Diprenorphine, and Buprenorphine Heterocycles. 39: 751. DOI: 10.3987/Com-94-S(B)70 |
0.323 |
|
| 1994 |
George C, Lahti PM, Modarelli DA, Inceli A. Substituted diphenyl oxalates Acta Crystallographica Section C Crystal Structure Communications. 50: 1308-1312. DOI: 10.1107/S0108270193012235 |
0.37 |
|
| 1994 |
Dave PR, Forohar F, Axenrod T, Bedford CD, Chaykovsky M, Rho M, Gilardi R, George C. Novel Spiro Substituted Cyclotriphosphazenes Incorporating Ethylenedinitramine Units Phosphorus, Sulfur, and Silicon and the Related Elements. 90: 175-184. DOI: 10.1080/10426509408016400 |
0.322 |
|
| 1994 |
Flippen-Anderson JL, Hruby VJ, Collins N, George C, Cudney B. X-ray Structure of [D-Pen2,D-Pen5]enkephalin, a Highly Potent, .delta. Opioid Receptor-Selective Compound: Comparisons with Proposed Solution Conformations Journal of the American Chemical Society. 116: 7523-7531. DOI: 10.1021/Ja00096A008 |
0.324 |
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| 1994 |
Flippen-Anderson JL, George C, Deschamps JR, Reddy PA, Lewin AH, Brine GA. X-ray structures of the ? opioid antagonist TIPP and a protected derivative of the ? opioid antagonist ICI 174,864 Letters in Peptide Science. 1: 107-115. DOI: 10.1007/Bf00128528 |
0.403 |
|
| 1993 |
Linders JTM, Monn JA, Mattson MV, George C, Jacobson AE, Rice KC. Synthesis and binding properties of MK-801 isothiocyanates; (+)-3-isothiocyanato-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrochloride: a new, potent and selective electrophilic affinity ligand for the NMDA receptor-coupled phencyclidine binding site Journal of Medicinal Chemistry. 36: 2499-2507. PMID 8355251 DOI: 10.1021/Jm00069A008 |
0.306 |
|
| 1993 |
Glassco W, Suchocki J, George C, Martin BR, May EL. Synthesis, optical resolution, absolute configuration, and preliminary pharmacology of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H- pyrrolo-[3,2-h]isoquinoline, a structural analog of nicotine. Journal of Medicinal Chemistry. 36: 3381-5. PMID 8230128 DOI: 10.1021/Jm00074A019 |
0.316 |
|
| 1993 |
Gilardi R, George C, Kane J, Eaton PE, Rao M. Azidocarbonyl-substituted cubanoureas Journal of Heterocyclic Chemistry. 30: 1389-1391. DOI: 10.1002/Jhet.5570300535 |
0.376 |
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| 1993 |
Gilardi R, George C, Karle J, Eaton PE, Fisher AM. Aza-analogues of cage compounds: Potential precursors to azacubanes and 1- azahomocubanes Journal of Heterocyclic Chemistry. 30: 1385-1388. DOI: 10.1002/Jhet.5570300534 |
0.355 |
|
| 1992 |
George C, Gilardi R, Flippen-Anderson JL. Structure of an acetone solvate of 7,9-diacetyl-2,5-dinitro-2,5,7,9-tetraazabicyclo[4.3.0]nonane Acta Crystallographica Section C Crystal Structure Communications. 48: 1699-1701. DOI: 10.1107/S0108270192000933 |
0.343 |
|
| 1992 |
Gilardi R, George C, Flippen-Anderson JL. Structure of 3-nitrato-1-nitroazetidine Acta Crystallographica Section C Crystal Structure Communications. 48: 1679-1680. DOI: 10.1107/S0108270192000696 |
0.336 |
|
| 1992 |
Flippen-Anderson JL, George C, Gilardi R. Structure of 2,4,6-trinitro-8,10-dipropionyl-2,4,6,8,10-pentaazabicyclo[5.3.0]decane Acta Crystallographica Section C Crystal Structure Communications. 48: 1530-1531. DOI: 10.1107/S0108270191015123 |
0.345 |
|
| 1992 |
George C, Gilardi R, Flippen-Anderson JL. Structure of 7-acetyl-2,5,9-trinitro-2,5,7,9-tetraazabicyclo[4.3.0]nonan-8-one Acta Crystallographica Section C Crystal Structure Communications. 48: 1527-1528. DOI: 10.1107/S0108270191014956 |
0.342 |
|
| 1992 |
Gilardi R, George C, Flippen-Anderson JL. Structures of (I) 6-nitro-2,4-dipropionyl-8-oxa-2,4,6-triazabicyclo[3.3.0]octane and (II) 2,4-diacetyl-6-nitro-8-oxa-2,4,6-triazabicyclo[3.3.0]octane Acta Crystallographica Section C Crystal Structure Communications. 48: 1528-1530. DOI: 10.1107/S0108270191014944 |
0.347 |
|
| 1992 |
Costa Bd, George C, Dominguez C. Synthesis of isothiocyanato-1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidines, potential irreversible ligands at the dopamine re-uptake site Journal of the Chemical Society-Perkin Transactions 1. 1671-1680. DOI: 10.1039/P19920001671 |
0.317 |
|
| 1992 |
Hendershot DG, Pazik JC, George C, Berry AD. Synthesis and characterization of neopentyl- and [(trimethylsilyl)methyl]antimony compounds. Molecular structures of (Me3CCH2)3Sb, (Me3CCH2)3SbI2, (Me3SiCH2)3Sb, and (Me3SiCH2)3SbI2 Organometallics. 11: 2163-2168. DOI: 10.1021/Om00042A033 |
0.354 |
|
| 1992 |
Willer RL, Day RS, Gilardi R, George C. Synthesis and properties of methylene-bis-(nitraminofurazans) Journal of Heterocyclic Chemistry. 29: 1835-1839. DOI: 10.1002/Jhet.5570290726 |
0.357 |
|
| 1992 |
Hinshaw JC, Edwards WW, George C, Gilardi R. Synthesis of 2,3,4,5‐tetranitropyrrole Journal of Heterocyclic Chemistry. 29: 1721-1724. DOI: 10.1002/Jhet.5570290708 |
0.324 |
|
| 1991 |
Pabuccuoglu V, Rozwadowska MD, Brossi A, Clark A, Hufford CD, George C, Flippen-Anderson JL. Oxoaporphine alkaloids: conversion of lysicamine into liriodendronine and its 2-O-methyl ether, and antifungal activity. Archiv Der Pharmazie. 324: 29-33. PMID 2043039 DOI: 10.1002/Ardp.19913240109 |
0.352 |
|
| 1991 |
Suchocki JA, May EL, Martin TJ, George C, Martin BR. Synthesis of 2-exo- and 2-endo-mecamylamine analogues. Structure-activity relationships for nicotinic antagonism in the central nervous system. Journal of Medicinal Chemistry. 34: 1003-10. PMID 2002445 DOI: 10.1021/Jm00107A019 |
0.371 |
|
| 1991 |
Iorio MA, Tomassini L, Mattson MV, George C, Jacobson AE. Synthesis, stereochemistry, and biological activity of the 1-(1-phenyl-2-methylcyclohexyl)piperidines and the 1-(1-phenyl-4-methylcyclohexyl)piperidines. Absolute configuration of the potent trans-(-)-1-(1-phenyl-2-methylcyclohexyl)piperidine. Journal of Medicinal Chemistry. 34: 2615-2623. PMID 1875352 DOI: 10.1021/Jm00112A041 |
0.361 |
|
| 1991 |
Flippen-Anderson JL, George C, Gilardi R, Zajac Jnr WW, Walters TR, Marchand A, Dave PR, Arney Jnr BE. Five 8,11-substituted pentacyclo[5.4.0.02,6.03,10.05,9]undecanes Acta Crystallographica Section C Crystal Structure Communications. 47: 813-817. DOI: 10.1107/S0108270190008563 |
0.327 |
|
| 1991 |
Gilardi R, Flippen-Anderson JL, George C. Structure of 2,2-dinitro-1,3-propanediyl bis[(N-pentafluorosulfanyl)carbamate] (I) and 2-fluoro-2,2-dinitroethyl (N-pentafluorosulfanyl)carbamate (II) Acta Crystallographica Section C Crystal Structure Communications. 47: 442-445. DOI: 10.1107/S0108270190006977 |
0.346 |
|
| 1991 |
Deschamps JR, George C, Flippen-Anderson JL, Musallam HA. Imidazolium chloride organophosphate antidotes Journal of Chemical Crystallography. 27: 541-548. DOI: 10.1007/Bf02576445 |
0.349 |
|
| 1990 |
Brossi A, Boyé O, Muzaffar A, Yeh HJC, Toome V, Wegrzynski B, George C. aS,7S‐absolute configuration of natural (−)‐colchicine and allocongeners Febs Letters. 262: 5-7. PMID 2318312 DOI: 10.1016/0014-5793(90)80139-A |
0.353 |
|
| 1990 |
Gilardi R, Flippen-Anderson JL, George C. Structures of 1,3,5-trinitro-2-oxo-1,3,5-triazacyclohexane (I) and 1,4-dinitro-2,5-dioxo-1,4-diazacyclohexane (II) Acta Crystallographica Section C Crystal Structure Communications. 46: 706-708. DOI: 10.1107/S0108270189012114 |
0.324 |
|
| 1990 |
George C, Flippen-Anderson JL, Gilardi R. Structure of 1,3-dinitro-1,3-diazacyclopentan-2-one Acta Crystallographica Section C Crystal Structure Communications. 46: 703-704. DOI: 10.1107/S0108270189011273 |
0.342 |
|
| 1990 |
Archibald TG, Gilardi R, Baum K, George C. Synthesis and x-ray crystal structure of 1,3,3-trinitroazetidine The Journal of Organic Chemistry. 55: 2920-2924. DOI: 10.1021/Jo00296A066 |
0.33 |
|
| 1990 |
Marchand AP, Annapurna P, Taylor RW, Simmons DL, Watson WH, Nagl A, Flippen-Anderson JL, Gilardi R, George C. Unusual behavior of 34:10,11-bis(2',3'-quinolino)tricyclo-[6.3.0.02,6] undecane upon attempted monoprotonation with triflic acid Tetrahedron. 46: 5077-5084. DOI: 10.1016/S0040-4020(01)87814-5 |
0.374 |
|
| 1989 |
Kim CH, Rothman RB, Jacobson AE, Mattson MV, Bykov V, Streaty RA, Klee WA, George C, Long JB, Rice KC. Probes for narcotic receptor mediated phenomena. 15. (3S,4S)-(+)-trans-3-methylfentanyl isothiocyanate, a potent site-directed acylating agent for the delta opioid receptors in vitro. Journal of Medicinal Chemistry. 32: 1392-8. PMID 2542560 DOI: 10.1021/Jm00126A040 |
0.322 |
|
| 1989 |
Gilardi R, George C. Structure of 2,4,6-trinitro-9-oxo-2,4,6,8-tetraaza-1-decanyl acetate Acta Crystallographica Section C Crystal Structure Communications. 45: 1262-1263. DOI: 10.1107/S0108270189003161 |
0.358 |
|
| 1989 |
Flippen-Anderson JL, Gilardi R, George C, Marchand AP, Dave PR. Structure of a cage dimer (I) and a dimer ketone (II) formed via thermal reaction of ethyl 3-phenyl-2-norbornadienecarboxylate with pentacarbonyliron Acta Crystallographica Section C Crystal Structure Communications. 45: 1171-1174. DOI: 10.1107/S0108270189000557 |
0.325 |
|
| 1989 |
Flippen-Anderson JL, Gilardi R, George C. Structures of two cyano nitramines (I): 1‐benzylnitrocyanamide and (II): 1,4‐nitrocyanamidylbutane Acta Crystallographica Section C-Crystal Structure Communications. 45: 1121-1122. DOI: 10.1107/S0108270189000272 |
0.326 |
|
| 1989 |
Marchand AP, Dave PR, Rajapaksa D, Arney BE, Flippen-Anderson JL, Gilardi R, George C. Synthesis of 4,4,8,8,11,11-hexanitropentacyclo[5.4.0.02,6.03,10.05,9]undecane The Journal of Organic Chemistry. 54: 1769-1771. DOI: 10.1021/Jo00268A056 |
0.417 |
|
| 1989 |
Itoh Y, Brossi A, Hamel E, Flippen-Anderson JL, George C. Colchicine models: Synthesis and Antitubulin Activity of 2?-Monosubstituted and 2?, 5-Disubstituted 2,3,4,4?-Tetramethoxy-1,1?-biphenyls. Synthesis of 4,4?, 5?, 6?-tetramethoxy-1,1?-biphenyl-2,3?-dicarboxylic acid Helvetica Chimica Acta. 72: 196-204. DOI: 10.1002/Hlca.19890720203 |
0.32 |
|
| 1988 |
de Costa BR, George C, Burke TR, Rafferty MF, Contreras PC, Mick SJ, Jacobson AE, Rice KC. Synthesis, configuration, and evaluation of two conformationally restrained analogues of phencyclidine. Journal of Medicinal Chemistry. 31: 1571-5. PMID 3397994 DOI: 10.1021/Jm00403A014 |
0.343 |
|
| 1988 |
Flippen-Anderson JL, Gilardi R, George C, Marchand AP, Jin P, Deshpande MN. Structure of a novel C22H24cage dimer Acta Crystallographica Section C Crystal Structure Communications. 44: 1617-1619. DOI: 10.1107/S0108270188005062 |
0.315 |
|
| 1988 |
Gilardi R, George C, Flippen-Anderson JL. Structure of a diamino-s-tetrazine Acta Crystallographica Section C Crystal Structure Communications. 44: 1686-1687. DOI: 10.1107/S0108270188005050 |
0.316 |
|
| 1988 |
Gessner W, Brossi A, Flippen-anderson JL, George C. C(9)-Butylated Lactams Related to Perhydrohistrionicotoxin Synthetic Communications. 18: 1371-1377. DOI: 10.1080/00397918808078805 |
0.311 |
|
| 1988 |
Sussangkarn K, Fodor G, Karle I, George C. Ascorbic Acid as a Michael Donor Tetrahedron. 44: 7047-7054. DOI: 10.1016/S0040-4020(01)86073-7 |
0.345 |
|
| 1987 |
DeCosta B, George C, Rothman RB, Jacobson AE, Rice KC. Synthesis and absolute configuration of optically pure enantiomers of a ϰ‐opioid receptor selective agonist Febs Letters. 223: 335-339. PMID 2822490 DOI: 10.1016/0014-5793(87)80315-0 |
0.312 |
|
| 1987 |
Arnold R, Fodor G, George C, Karle I. The Michael adduct of L-ascorbic acid to methyl vinyl ketone: its remarkable self-condensation and other reactions Canadian Journal of Chemistry. 65: 131-136. DOI: 10.1139/V87-021 |
0.326 |
|
| 1987 |
Flippen-Anderson JL, Gilardi R, George C. Structure of 6-hydroxy-2,5-dinitro-2,5-diazacyclohexyl acetate Acta Crystallographica Section C Crystal Structure Communications. 43: 2022-2023. DOI: 10.1107/S0108270187089170 |
0.32 |
|
| 1987 |
Marchand AP, Jin P, Flippen-Anderson JL, Gilardi R, George C. A novel rearrangement in a 1,3-bishomocubyl ring system Journal of the Chemical Society, Chemical Communications. 14: 1108-1109. DOI: 10.1039/C39870001108 |
0.356 |
|
| 1987 |
Koppes WM, Chaykovsky M, Adolph HG, Gilardi R, George C. Synthesis and structure of some peri-substituted 2,4,6,8-tetraazabicyclo[3.3.0]octanes The Journal of Organic Chemistry. 52: 1113-1119. DOI: 10.1021/Jo00382A025 |
0.342 |
|
| 1986 |
Flippen-Anderson JL, Gilardi R, George C. Neurotoxins producing Parkinson's syndrome Acta Crystallographica Section C Crystal Structure Communications. 42: 1185-1189. DOI: 10.1107/S0108270186092946 |
0.321 |
|
| 1986 |
Gleason FK, Porwoll J, Flippen-Anderson JL, George C. X-ray structure determination of the naturally occurring isomer of cyanobacterin The Journal of Organic Chemistry. 51: 1615-1616. DOI: 10.1021/Jo00359A050 |
0.309 |
|
| 1986 |
GLEASON FK, PORWOLL J, FLIPPEN-ANDERSON JL, GEORGE C. ChemInform Abstract: X-Ray Structure Determination of the Naturally Occurring Isomer of Cyanobacterin. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198650066 |
0.316 |
|
| 1984 |
George C, Gilardi R. Structure of 1,3,5,7-tetranitroadamantane, C10H12N4O8 Acta Crystallographica Section C Crystal Structure Communications. 40: 674-676. DOI: 10.1107/S010827018400528X |
0.369 |
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