| Year |
Citation |
Score |
| 2024 |
Rachwalski K, Madden SJ, Ritchie N, French S, Bhando T, Girgis-Gabardo A, Tu M, Gordzevich R, Ives R, Guo ABY, Johnson JW, Xu Y, Kapadia SB, Magolan J, Brown ED. A screen for cell envelope stress uncovers an inhibitor of prolipoprotein diacylglyceryl transferase, Lgt, in . Iscience. 27: 110894. PMID 39376497 DOI: 10.1016/j.isci.2024.110894 |
0.772 |
|
| 2024 |
Kieliszek AM, Mobilio D, Bassey-Archibong BI, Johnson JW, Piotrowski ML, de Araujo ED, Sedighi A, Aghaei N, Escudero L, Ang P, Gwynne WD, Zhang C, Quaile A, McKenna D, Subapanditha M, et al. De novo GTP synthesis is a metabolic vulnerability for the interception of brain metastases. Cell Reports. Medicine. 101755. PMID 39366383 DOI: 10.1016/j.xcrm.2024.101755 |
0.73 |
|
| 2024 |
French S, Guo ABY, Ellis MJ, Deisinger JP, Johnson JW, Rachwalski K, Piquette ZA, Lluka T, Zary M, Gamage S, Magolan J, Brown ED. A platform for predicting mechanism of action based on bacterial transcriptional responses identifies an unusual DNA gyrase inhibitor. Cell Reports. 43: 114053. PMID 38578824 DOI: 10.1016/j.celrep.2024.114053 |
0.777 |
|
| 2024 |
Puumala E, Sychantha D, Lach E, Reeves S, Nabeela S, Fogal M, Nigam A, Johnson JW, Aspuru-Guzik A, Shapiro RS, Uppuluri P, Kalyaanamoorthy S, Magolan J, Whitesell L, Robbins N, et al. Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology. PMID 38402621 DOI: 10.1016/j.chembiol.2024.01.010 |
0.747 |
|
| 2023 |
Cook MA, Pallant D, Ejim L, Sutherland AD, Wang X, Johnson JW, McCusker S, Chen X, George M, Chou S, Koteva K, Wang W, Hobson C, Hackenberger D, Waglechner N, et al. Lessons from assembling a microbial natural product and pre-fractionated extract library in an academic laboratory. Journal of Industrial Microbiology & Biotechnology. PMID 38052426 DOI: 10.1093/jimb/kuad042 |
0.535 |
|
| 2022 |
Klobucar K, Jardine E, Farha MA, MacKinnon MR, Fragis M, Nkonge B, Bhando T, Borrillo L, Tsai CN, Johnson JW, Coombes BK, Magolan J, Brown ED. Genetic and Chemical Screening Reveals Targets and Compounds to Potentiate Gram-Positive Antibiotics against Gram-Negative Bacteria. Acs Infectious Diseases. PMID 36098580 DOI: 10.1021/acsinfecdis.2c00357 |
0.676 |
|
| 2022 |
Johnson JW, Ellis MJ, Piquette ZA, MacNair C, Carfrae L, Bhando T, Ritchie NE, Saliba P, Brown ED, Magolan J. Antibacterial Activity of Metergoline Analogues: Revisiting the Ergot Alkaloid Scaffold for Antibiotic Discovery. Acs Medicinal Chemistry Letters. 13: 284-291. PMID 35178184 DOI: 10.1021/acsmedchemlett.1c00648 |
0.779 |
|
| 2021 |
Alder A, Struck NS, Xu M, Johnson JW, Wang W, Pallant D, Cook MA, Rambow J, Lemcke S, Gilberger TW, Wright GD. A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity. Cell Chemical Biology. PMID 34710358 DOI: 10.1016/j.chembiol.2021.10.005 |
0.488 |
|
| 2021 |
Klobucar K, Côté JP, French S, Borrillo L, Guo ABY, Serrano-Wu MH, Lee KK, Hubbard B, Johnson JW, Gaulin JL, Magolan J, Hung DT, Brown ED. Chemical Screen for Vancomycin Antagonism Uncovers Probes of the Gram-Negative Outer Membrane. Acs Chemical Biology. PMID 33974796 DOI: 10.1021/acschembio.1c00179 |
0.767 |
|
| 2021 |
Sguazzin MA, Johnson JW, Magolan J. Hexafluoroisopropyl Sulfamate: A Useful Reagent for the Synthesis of Sulfamates and Sulfamides. Organic Letters. 23: 3373-3378. PMID 33861615 DOI: 10.1021/acs.orglett.1c00855 |
0.709 |
|
| 2019 |
Ellis MJ, Tsai CN, Johnson JW, French S, Elhenawy W, Porwollik S, Andrews-Polymenis H, McClelland M, Magolan J, Coombes BK, Brown ED. A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium. Nature Communications. 10: 197. PMID 30643129 DOI: 10.1038/S41467-018-08190-X |
0.768 |
|
| 2017 |
Abboud MI, Kosmopoulou M, Krismanich A, Johnson JW, Hinchliffe P, Brem J, Claridge TDW, Spencer J, Schofield C, Dmitrienko GI. Cyclobutanone Mimics of Intermediates in Metallo-β-Lactamase Catalysis. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29250863 DOI: 10.1002/Chem.201705886 |
0.566 |
|
| 2016 |
Pawlowski AC, Johnson JW, Wright GD. Evolving medicinal chemistry strategies in antibiotic discovery. Current Opinion in Biotechnology. 42: 108-117. PMID 27116217 DOI: 10.1016/J.Copbio.2016.04.006 |
0.51 |
|
| 2013 |
Otero LH, Rojas-Altuve A, Llarrull LI, Carrasco-López C, Kumarasiri M, Lastochkin E, Fishovitz J, Dawley M, Hesek D, Lee M, Johnson JW, Fisher JF, Chang M, Mobashery S, Hermoso JA. How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function. Proceedings of the National Academy of Sciences of the United States of America. 110: 16808-13. PMID 24085846 DOI: 10.1073/Pnas.1300118110 |
0.521 |
|
| 2013 |
Johnson JW, Fisher JF, Mobashery S. Bacterial cell-wall recycling. Annals of the New York Academy of Sciences. 1277: 54-75. PMID 23163477 DOI: 10.1111/J.1749-6632.2012.06813.X |
0.526 |
|
| 2010 |
Johnson JW, Gretes M, Goodfellow VJ, Marrone L, Heynen ML, Strynadka NC, Dmitrienko GI. Cyclobutanone analogues of beta-lactams revisited: insights into conformational requirements for inhibition of serine- and metallo-beta-lactamases. Journal of the American Chemical Society. 132: 2558-60. PMID 20141132 DOI: 10.1021/ja9086374 |
0.591 |
|
| 2008 |
Johnson JW, Evanoff DP, Savard ME, Lange G, Ramadhar TR, Assoud A, Taylor NJ, Dmitrienko GI. Cyclobutanone mimics of penicillins: effects of substitution on conformation and hemiketal stability. The Journal of Organic Chemistry. 73: 6970-82. PMID 18710291 DOI: 10.1021/Jo801274M |
0.557 |
|
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