Hung-Wen Li, Ph.D. - Publications

Affiliations: 
Chemistry National Taiwan University, Taipei, Taipei City, Taiwan 

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Peng JC, Chang HY, Sun YL, Prentiss M, Li HW, Chi P. Hop2-Mnd1 functions as a DNA sequence fidelity switch in Dmc1-mediated DNA recombination. Nature Communications. 15: 9266. PMID 39463417 DOI: 10.1038/s41467-024-53641-3  0.443
2024 Wei CD, Chang HY, Lu CH, Chang CC, Furukohri A, Mwaniki S, Shinohara A, Chi P, Li HW. Mei5-Sae3 stabilizes Dmc1 nucleating clusters for efficient Dmc1 assembly on RPA-coated single-stranded DNA. Nucleic Acids Research. PMID 39275989 DOI: 10.1093/nar/gkae780  0.4
2023 Guh CL, Lei KH, Chen YA, Jiang YZ, Chang HY, Liaw H, Li HW, Yen HY, Chi P. RAD51 paralogs synergize with RAD51 to protect reversed forks from cellular nucleases. Nucleic Acids Research. PMID 37843130 DOI: 10.1093/nar/gkad856  0.39
2023 Lee W, Iwasaki H, Tsubouchi H, Li HW. Hop2-Mnd1 and Swi5-Sfr1 stimulate Dmc1 filament assembly using distinct mechanisms. Nucleic Acids Research. PMID 37395447 DOI: 10.1093/nar/gkad561  0.468
2021 Lei KH, Yang HL, Chang HY, Yeh HY, Nguyen DD, Lee TY, Lyu X, Chastain M, Chai W, Li HW, Chi P. Crosstalk between CST and RPA regulates RAD51 activity during replication stress. Nature Communications. 12: 6412. PMID 34741010 DOI: 10.1038/s41467-021-26624-x  0.303
2021 Lee TY, Li YC, Lin MG, Hsiao CD, Li HW. Single-molecule binding characterization of primosomal protein PriA involved in replication restart. Physical Chemistry Chemical Physics : Pccp. 23: 13745-13751. PMID 34159970 DOI: 10.1039/d1cp00638j  0.449
2021 Lu CH, Lan WH, Li HW. Single-Molecule Tethered Particle Motion Studies on the DNA Recombinase Filament Assembly and Disassembly. Methods in Molecular Biology (Clifton, N.J.). 2281: 135-149. PMID 33847956 DOI: 10.1007/978-1-0716-1290-3_8  0.739
2021 Lin YY, Li MH, Chang YC, Fu PY, Ohniwa RL, Li HW, Lin JJ. Dynamic DNA Shortening by Telomere-Binding Protein Cdc13. Journal of the American Chemical Society. PMID 33831300 DOI: 10.1021/jacs.1c00820  0.47
2021 Luo SC, Yeh HY, Lan WH, Wu YM, Yang CH, Chang HY, Su GC, Lee CY, Wu WJ, Li HW, Ho MC, Chi P, Tsai MD. Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures. Nature Communications. 12: 115. PMID 33446654 DOI: 10.1038/s41467-020-20258-1  0.41
2020 Chang HY, Lee CY, Lu CH, Lee W, Yang HL, Yeh HY, Li HW, Chi P. Microcephaly family protein MCPH1 stabilizes RAD51 filaments. Nucleic Acids Research. PMID 32735676 DOI: 10.1093/Nar/Gkaa636  0.722
2020 Tirtom NE, Hsu Y, Li HW. Polyamines stimulate RecA-mediated recombination by condensing duplex DNA and stabilizing intermediates. Physical Chemistry Chemical Physics : Pccp. PMID 32432615 DOI: 10.1039/d0cp01061h  0.45
2020 Lan WH, Lin SY, Kao CY, Chang WH, Yeh HY, Chang HY, Chi P, Li HW. Rad51 facilitates filament assembly of meiosis-specific Dmc1 recombinase. Proceedings of the National Academy of Sciences of the United States of America. PMID 32404423 DOI: 10.1073/Pnas.1920368117  0.566
2019 Lin YH, Chu CC, Fan HF, Wang PY, Cox MM, Li HW. A 5'-to-3' strand exchange polarity is intrinsic to RecA nucleoprotein filaments in the absence of ATP hydrolysis. Nucleic Acids Research. PMID 30916331 DOI: 10.1093/Nar/Gkz189  0.475
2018 Lu CH, Yeh HY, Su GC, Ito K, Kurokawa Y, Iwasaki H, Chi P, Li HW. Swi5-Sfr1 stimulates Rad51 recombinase filament assembly by modulating Rad51 dissociation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30297419 DOI: 10.1073/Pnas.1812753115  0.734
2017 Lu CH, Chang TT, Cho CC, Lin HC, Li HW. Stable Nuclei of Nucleoprotein Filament and High ssDNA Binding Affinity Contribute to Enhanced RecA E38K Recombinase Activity. Scientific Reports. 7: 14964. PMID 29097773 DOI: 10.1038/S41598-017-15088-Z  0.704
2017 Cho CC, Chung C, Li HW. How Chi Sequence Modifies RecBCD Single-Stranded DNA Translocase Activities. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 29032606 DOI: 10.1002/Cphc.201700840  0.507
2017 Wu HY, Lu CH, Li HW. RecA-SSB Interaction Modulates RecA Nucleoprotein Filament Formation on SSB-Wrapped DNA. Scientific Reports. 7: 11876. PMID 28928411 DOI: 10.1038/S41598-017-12213-W  0.741
2017 Lu CH, Li HW. DNA with Different Local Torsional States Affects RecA-Mediated Recombination Progression. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. PMID 28054431 DOI: 10.1002/Cphc.201601281  0.742
2017 Kao W, Li H. An Efficient Bead‐captured Denaturation Method for Preparing Long Single‐stranded DNA Journal of the Chinese Chemical Society. 64: 1065-1070. DOI: 10.1002/Jccs.201700142  0.52
2016 Chen YF, Lu CY, Lin YC, Yu TY, Chang CP, Li JR, Li HW, Lin JJ. Modulation of yeast telomerase activity by Cdc13 and Est1 in vitro. Scientific Reports. 6: 34104. PMID 27659693 DOI: 10.1038/Srep34104  0.517
2016 Carter AR, Seaberg MH, Fan HF, Sun G, Wilds CJ, Li HW, Perkins TT. Sequence-dependent nanometer-scale conformational dynamics of individual RecBCD-DNA complexes. Nucleic Acids Research. PMID 27220465 DOI: 10.1093/Nar/Gkw445  0.453
2016 Li JR, Lu CY, Lin JJ, Li HW. Multiple Pif1 helicases are required to sequentially disrupt G-quadruplex structure and unwind duplex DNA. Biochemical and Biophysical Research Communications. PMID 27079238 DOI: 10.1016/J.Bbrc.2016.04.046  0.45
2016 Wang CC, Wu SM, Li HW, Chang HT. Biomedical Applications of DNA-Conjugated Gold Nanoparticles. Chembiochem : a European Journal of Chemical Biology. PMID 26864481 DOI: 10.1002/Cbic.201600014  0.335
2015 Xu J, Wu ZS, Shen W, Xu H, Li H, Jia L. Cascade DNA nanomachine and exponential amplification biosensing. Biosensors & Bioelectronics. 73: 19-25. PMID 26042874 DOI: 10.1016/j.bios.2015.05.045  0.408
2015 Piechura JR, Tseng TL, Hsu HF, Byrne RT, Windgassen TA, Chitteni-Pattu S, Battista JR, Li HW, Cox MM. Biochemical characterization of RecA variants that contribute to extreme resistance to ionizing radiation. Dna Repair. 26: 30-43. PMID 25559557 DOI: 10.1016/J.Dnarep.2014.12.001  0.476
2014 Li JR, Yu TY, Chien IC, Lu CY, Lin JJ, Li HW. Pif1 regulates telomere length by preferentially removing telomerase from long telomere ends. Nucleic Acids Research. 42: 8527-36. PMID 24981509 DOI: 10.1093/Nar/Gku541  0.441
2014 Yuan Z, Chen YC, Li HW, Chang HT. Fluorescent silver nanoclusters stabilized by DNA scaffolds. Chemical Communications (Cambridge, England). 50: 9800-15. PMID 24901353 DOI: 10.1039/C4Cc02981J  0.413
2014 Wu HY, Li HW. Crowding alters the dynamics and the length of RecA nucleoprotein filaments in RecA-mediated strand exchange. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 15: 80-4. PMID 24281991 DOI: 10.1002/Cphc.201300835  0.403
2014 Su GC, Chung CI, Liao CY, Lin SW, Tsai CT, Huang T, Li HW, Chi P. Enhancement of ADP release from the RAD51 presynaptic filament by the SWI5-SFR1 complex. Nucleic Acids Research. 42: 349-58. PMID 24078249 DOI: 10.1093/Nar/Gkt879  0.536
2014 Chung C, Li H. RecBCD Fails to Bypass the 5'-To-3' Single-Stranded DNA Gap After Translocating Along Individual Chi-Containing Duplex DNA Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.473  0.563
2014 Huang T, Chang T, Li H. Effect of G-Quadruplex Stabilizing Compound on the Folding and Unfolding Pathway of Human Telomeric DNA Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.2233  0.446
2014 Li J, Chien Y, Lin J, Li H. Pif1 Regulates Telomere Length by Removing Telomerase from Telomere Ends Biophysical Journal. 106: 3-4. DOI: 10.1016/J.Bpj.2013.11.2227  0.432
2013 Lu YW, Huang T, Tsai CT, Chang YY, Li HW, Hsu CH, Fan HF. Using single-molecule approaches to study archaeal DNA-binding protein Alba1. Biochemistry. 52: 7714-22. PMID 24093364 DOI: 10.1021/Bi4010478  0.553
2013 Chung C, Li HW. Direct observation of RecBCD helicase as single-stranded DNA translocases. Journal of the American Chemical Society. 135: 8920-5. PMID 23718269 DOI: 10.1021/Ja401626T  0.55
2013 Liu SW, Chu JF, Tsai CT, Fang HC, Chang TC, Li HW. Assaying the binding strength of G-quadruplex ligands using single-molecule TPM experiments. Analytical Biochemistry. 436: 101-8. PMID 23376016 DOI: 10.1016/J.Ab.2013.01.021  0.413
2013 Chung C, Li H. 2P146 Observing RecBCD Translocation along Individual Chi-Containing Gapped DNA(11. Molecular motor,Poster) Seibutsu Butsuri. 53. DOI: 10.2142/Biophys.53.S183_2  0.394
2013 Chung C, Li H. Direct Observation of Recbcd Helicase as ssDNA Translocases Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.988  0.548
2013 Liao S, Wu H, Li H. Salt‐Dependence of Homology Searching Step by RecA Nucleoprotein Filaments Journal of the Chinese Chemical Society. 60: 695-698. DOI: 10.1002/Jccs.201300102  0.532
2012 Liao S, Chen Y, Li H. Studying RecA Homology Search Mechanism using Single-Molecule Methods Biophysical Journal. 102: 281a. DOI: 10.1016/J.Bpj.2011.11.1551  0.503
2011 Lo YH, Liu SW, Sun YJ, Li HW, Lizz HW, Hsiao CD. Mutations altering the interplay between GkDnaC helicase and DNA reveal an insight into helicase unwinding. Plos One. 6: e29016. PMID 22174946 DOI: 10.1371/Journal.Pone.0029016  0.551
2011 Hsu HF, Ngo KV, Chitteni-Pattu S, Cox MM, Li HW. Investigating Deinococcus radiodurans RecA protein filament formation on double-stranded DNA by a real-time single-molecule approach. Biochemistry. 50: 8270-80. PMID 21853996 DOI: 10.1021/Bi200423T  0.575
2011 Fan HF, Cox MM, Li HW. Developing single-molecule TPM experiments for direct observation of successful RecA-mediated strand exchange reaction. Plos One. 6: e21359. PMID 21765895 DOI: 10.1371/Journal.Pone.0021359  0.552
2011 Liu S, Lo Y, Li H, Hsiao C. Direct Observation of Replicative Helicase DnaC by Single-Molecule Tethered Particle Motion (TPM) Experiments Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.602  0.561
2011 Fan H, Cox MM, Li H. PlatformsPLATFORM AB: Protein-Nucleic Acid InteractionUsing Real-Time, Single-Molecule Experiments to Monitor Reca-Mediated Pairing and Strand Exchange Reactions at Various Nucleotide States Biophysical Journal. DOI: 10.1016/J.Bpj.2010.12.1262  0.368
2010 Chu JF, Chang TC, Li HW. Single-molecule TPM studies on the conversion of human telomeric DNA. Biophysical Journal. 98: 1608-16. PMID 20409481 DOI: 10.1016/J.Bpj.2009.12.4328  0.445
2010 Perkins TT, Li HW. Single-molecule studies of RecBCD. Methods in Molecular Biology (Clifton, N.J.). 587: 155-72. PMID 20225148 DOI: 10.1007/978-1-60327-355-8_11  0.393
2010 Chang J, Li H. Intersubunit Regulation Between Nuclease and Helicase Domains of Recbcd Enzyme Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.405  0.457
2010 Fan H, Cox MM, Li H. Using Real-Time, Single-Molecule Experiments To Monitor RecA-Mediated Pairing and Strand Exchange Reactions in Various Nucleotide States Biophysical Journal. 98: 71a. DOI: 10.1016/J.Bpj.2009.12.404  0.5
2010 Hosotani M, Carter AR, Fan H, Li H, Perkins TT. Conformational Dynamics of Single RecBCD Molecules Biophysical Journal. 98: 65a. DOI: 10.1016/J.Bpj.2009.12.371  0.535
2010 Hsu H, Li H, Cox MM. Investigating the Nucleation and Extension Rates of E.coli and Deinococcus RecA Along Duplex DNA Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.354  0.571
2010 Chu J, Wang Z, Li H, Chang∗ T. Does the Unfolding State of the Human Telomere Exist Upon Ion Exchange Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.1443  0.304
2009 Fan HF, Li HW. Studying RecBCD helicase translocation along Chi-DNA using tethered particle motion with a stretching force. Biophysical Journal. 96: 1875-83. PMID 19254546 DOI: 10.1016/J.Bpj.2008.11.048  0.524
2009 Chu J, Chang T, Li H. Structure Conversion Of Human Telomeric Sequence Studied By Single-molecule Tethered Particle Motion Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1726  0.374
2004 Perkins TT, Li HW, Dalal RV, Gelles J, Block SM. Forward and reverse motion of single RecBCD molecules on DNA. Biophysical Journal. 86: 1640-8. PMID 14990491 DOI: 10.1016/S0006-3495(04)74232-0  0.67
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