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Gregory Fairn - Publications

Affiliations: 
2012-2020 St. Michael's Hospital, University of Toronto 
 2021- Dalhousie University, Halifax, Nova Scotia, Canada 
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Montaño-Rendón F, Walpole GFW, Krause M, Hammond GRV, Grinstein S, Fairn GD. PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages. The Journal of Cell Biology. 221. PMID 36165850 DOI: 10.1083/jcb.202207042  0.521
2022 Walpole GFW, Pacheco J, Chauhan N, Clark J, Anderson KE, Abbas YM, Brabant-Kirwan D, Montaño-Rendón F, Liu Z, Zhu H, Brumell JH, Deiters A, Stephens LR, Hawkins PT, Hammond GRV, ... ... Fairn GD, et al. Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase. Nature Cell Biology. PMID 35484249 DOI: 10.1038/s41556-022-00895-y  0.643
2022 Cabral-Dias R, Lucarelli S, Zak K, Rahmani S, Judge G, Abousawan J, DiGiovanni LF, Vural D, Anderson KE, Sugiyama MG, Genc G, Hong W, Botelho RJ, Fairn GD, Kim PK, et al. Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling. The Journal of Cell Biology. 221. PMID 35238864 DOI: 10.1083/jcb.201808181  0.595
2021 Sugiyama MG, Cui H, Redka DS, Karimzadeh M, Rujas E, Maan H, Hayat S, Cheung K, Misra R, McPhee JB, Viirre RD, Haller A, Botelho RJ, Karshafian R, Sabatinos SA, ... Fairn GD, et al. Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease. Scientific Reports. 11: 23315. PMID 34857794 DOI: 10.1038/s41598-021-02432-7  0.54
2019 Lu Y, Zheng Y, Coyaud É, Zhang C, Selvabaskaran A, Yu Y, Xu Z, Weng X, Chen JS, Meng Y, Warner N, Cheng X, Liu Y, Yao B, Hu H, ... ... Fairn GD, et al. Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Science (New York, N.Y.). 366: 460-467. PMID 31649195 DOI: 10.1126/Science.Aau6391  0.576
2019 Yang Y, Park M, Maekawa M, Fairn GD. Enforced expression of phosphatidylinositol 4-phosphate 5-kinase homolog alters PtdIns(4,5)P distribution and the localization of small G-proteins. Scientific Reports. 9: 14789. PMID 31616009 DOI: 10.1038/s41598-019-51272-z  0.365
2019 Levin-Konigsberg R, Montaño-Rendón F, Keren-Kaplan T, Li R, Ego B, Mylvaganam S, DiCiccio JE, Trimble WS, Bassik MC, Bonifacino JS, Fairn GD, Grinstein S. Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling. Nature Cell Biology. PMID 31570833 DOI: 10.1038/S41556-019-0394-2  0.468
2019 Ostrowski PP, Freeman SA, Fairn G, Grinstein S. Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides. Developmental Cell. PMID 31231039 DOI: 10.1016/J.Devcel.2019.05.028  0.661
2018 Tan JMJ, Mellouk N, Osborne SE, Ammendolia DA, Dyer DN, Li R, Brunen D, van Rijn JM, Huang J, Czuczman MA, Cemma MA, Won AM, Yip CM, Xavier RJ, MacDuff DA, ... ... Fairn GD, et al. An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread. Nature Microbiology. 3: 1472-1485. PMID 30478389 DOI: 10.1038/S41564-018-0293-5  0.588
2018 Truong D, Boddy KC, Canadien V, Brabant D, Fairn GD, D'Costa VM, Coyaud E, Raught B, Perez-Sala D, Park WS, Do Heo W, Grinstein S, Brumell JH. Salmonella exploits host Rho GTPase signalling pathways through the phosphatase activity of SopB. Cellular Microbiology. e12938. PMID 30010242 DOI: 10.1111/Cmi.12938  0.637
2018 Lu SM, Fairn GD. 7-Ketocholesterol Impairs Phagocytosis and Efferocytosis via Dysregulation of Phosphatidylinositol 4,5-bisphosphate. Traffic (Copenhagen, Denmark). PMID 29693767 DOI: 10.1111/tra.12576  0.362
2018 Yang Y, Lee M, Fairn GD. Phospholipid Subcellular Localization and Dynamics. The Journal of Biological Chemistry. PMID 29588369 DOI: 10.1074/jbc.R117.000582  0.341
2018 Sohn M, Korzeniowski M, Zewe JP, Wills RC, Hammond GRV, Humpolickova J, Vrzal L, Chalupska D, Veverka V, Fairn GD, Boura E, Balla T. PI(4,5)Pcontrols plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites. The Journal of Cell Biology. PMID 29472386 DOI: 10.1083/Jcb.201710095  0.329
2017 Hirama T, Lu SM, Kay JG, Maekawa M, Kozlov MM, Grinstein S, Fairn GD. Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis. Nature Communications. 8: 1393. PMID 29123120 DOI: 10.1038/S41467-017-01554-9  0.497
2017 Hirama T, Das R, Yang Y, Ferguson C, Won A, Yip CM, Kay JG, Grinstein S, Parton RG, Fairn GD. Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane. The Journal of Biological Chemistry. PMID 28698382 DOI: 10.1074/Jbc.M117.791400  0.546
2017 Hua R, Cheng D, Coyaud É, Freeman S, Di Pietro E, Wang Y, Vissa A, Yip CM, Fairn GD, Braverman N, Brumell JH, Trimble WS, Raught B, Kim PK. VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis. The Journal of Cell Biology. PMID 28108526 DOI: 10.1083/Jcb.201608128  0.675
2017 Bone LN, Dayam RM, Lee M, Kono N, Fairn GD, Arai H, Botelho RJ, Antonescu CN. The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic. Molecular Biology of the Cell. 28: 161-172. PMID 28035047 DOI: 10.1091/Mbc.E16-09-0668  0.654
2017 Levin R, Hammond GR, Balla T, De Camilli P, Fairn GD, Grinstein S. Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis. Molecular Biology of the Cell. 28: 128-140. PMID 28035045 DOI: 10.1091/Mbc.E16-06-0451  0.515
2017 Lu SM, Grinstein S, Fairn GD. Quantitative Live-Cell Fluorescence Microscopy During Phagocytosis. Methods in Molecular Biology (Clifton, N.J.). 1519: 79-91. PMID 27815874 DOI: 10.1007/978-1-4939-6581-6_6  0.465
2016 Ostrowski PP, Fairn GD, Grinstein S, Johnson DE. Cresyl violet: a superior fluorescent lysosomal marker. Traffic (Copenhagen, Denmark). PMID 27621028 DOI: 10.1111/Tra.12447  0.419
2016 Schlam D, Canton J, Carreño M, Kopinski H, Freeman SA, Grinstein S, Fairn GD. Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis. Mbio. 7. PMID 27048806 DOI: 10.1128/Mbio.02242-15  0.692
2016 Maekawa M, Yang Y, Fairn GD. Perfringolysin O Theta Toxin as a Tool to Monitor the Distribution and Inhomogeneity of Cholesterol in Cellular Membranes. Toxins. 8. PMID 27005662 DOI: 10.3390/toxins8030067  0.311
2015 Schlam D, Bagshaw RD, Freeman SA, Collins RF, Pawson T, Fairn GD, Grinstein S. Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins. Nature Communications. 6: 8623. PMID 26465210 DOI: 10.1038/Ncomms9623  0.665
2013 Mukherjee D, Sen A, Boettner DR, Fairn GD, Schlam D, Bonilla Valentin FJ, Michael McCaffery J, Hazbun T, Staiger CJ, Grinstein S, Lemmon SK, Claudio Aguilar R. Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes. Journal of Cell Science. 126: 4560-71. PMID 23943876 DOI: 10.1242/Jcs.117663  0.532
2013 Strijbis K, Tafesse FG, Fairn GD, Witte MD, Dougan SK, Watson N, Spooner E, Esteban A, Vyas VK, Fink GR, Grinstein S, Ploegh HL. Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. Plos Pathogens. 9: e1003446. PMID 23825946 DOI: 10.1371/Journal.Ppat.1003446  0.484
2013 Schlam D, Bohdanowicz M, Chatgilialoglu A, Chatilialoglu A, Steinberg BE, Ueyama T, Du G, Grinstein S, Fairn GD. Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. The Journal of Biological Chemistry. 288: 23090-104. PMID 23814057 DOI: 10.1074/Jbc.M113.457606  0.46
2013 Bohdanowicz M, Schlam D, Hermansson M, Rizzuti D, Fairn GD, Ueyama T, Somerharju P, Du G, Grinstein S. Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Molecular Biology of the Cell. 24: 1700-12, S1-7. PMID 23576545 DOI: 10.1091/Mbc.E12-11-0789  0.544
2012 Fairn GD, Grinstein S. Cell biology. Precursor or charge supplier? Science (New York, N.Y.). 337: 653-4. PMID 22879491 DOI: 10.1126/science.1227096  0.366
2012 Fairn GD, Grinstein S. How nascent phagosomes mature to become phagolysosomes. Trends in Immunology. 33: 397-405. PMID 22560866 DOI: 10.1016/j.it.2012.03.003  0.529
2012 Liu J, Fairn GD, Ceccarelli DF, Sicheri F, Wilde A. Cleavage furrow organization requires PIP 2-mediated recruitment of anillin Current Biology. 22: 64-69. PMID 22197245 DOI: 10.1016/J.Cub.2011.11.040  0.339
2011 Fairn GD, Hermansson M, Somerharju P, Grinstein S. Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity. Nature Cell Biology. 13: 1424-30. PMID 21964439 DOI: 10.1038/Ncb2351  0.451
2011 Carraro-Lacroix LR, Jaumouillé V, Fairn GD, Grinstein S. A weak base-generating system suitable for selective manipulation of lysosomal pH. Traffic (Copenhagen, Denmark). 12: 1490-500. PMID 21819499 DOI: 10.1111/J.1600-0854.2011.01266.X  0.384
2011 Fairn GD, Schieber NL, Ariotti N, Murphy S, Kuerschner L, Webb RI, Grinstein S, Parton RG. High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. The Journal of Cell Biology. 194: 257-75. PMID 21788369 DOI: 10.1083/Jcb.201012028  0.488
2009 Fairn GD, Ogata K, Botelho RJ, Stahl PD, Anderson RA, De Camilli P, Meyer T, Wodak S, Grinstein S. An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. The Journal of Cell Biology. 187: 701-14. PMID 19951917 DOI: 10.1085/Jgp1351Oia1  0.684
2009 Yeung T, Heit B, Dubuisson JF, Fairn GD, Chiu B, Inman R, Kapus A, Swanson M, Grinstein S. Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. The Journal of Cell Biology. 185: 917-28. PMID 19487458 DOI: 10.1085/Jgp1341Oia1  0.527
2008 Fairn GD, Grinstein S. Cell biology. A one-sided signal. Science (New York, N.Y.). 320: 458-60. PMID 18436763 DOI: 10.1126/Science.1158173  0.478
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