Joseph Lachance - Publications

Affiliations: 
 
Area:
Human evolutionary genomics, population genetics
Website:
https://popgen.gatech.edu

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Janivara R, Chen WC, Hazra U, Baichoo S, Agalliu I, Kachambwa P, Simonti CN, Brown LM, Tambe SP, Kim MS, Harlemon M, Jalloh M, Muzondiwa D, Naidoo D, Ajayi OO, ... ... Lachance J, et al. Heterogeneous genetic architectures of prostate cancer susceptibility in sub-Saharan Africa. Nature Genetics. PMID 39358599 DOI: 10.1038/s41588-024-01931-3  0.34
2024 Pfennig A, Lachance J. The evolutionary fate of Neanderthal DNA in 30,780 admixed genomes with recent African-like ancestry. Biorxiv : the Preprint Server For Biology. PMID 39091830 DOI: 10.1101/2024.07.25.605203  0.338
2024 Brown LM, Elbon MC, Bharadwaj A, Damle G, Lachance J. Does effective population size govern evolutionary differences in telomere length? Genome Biology and Evolution. PMID 38771124 DOI: 10.1093/gbe/evae111  0.325
2024 Janivara R, Hazra U, Pfennig A, Harlemon M, Kim MS, Eaaswarkhanth M, Chen WC, Ogunbiyi A, Kachambwa P, Petersen LN, Jalloh M, Mensah JE, Adjei AA, Adusei B, Joffe M, ... ... Lachance J, et al. Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men. Biorxiv : the Preprint Server For Biology. PMID 38293167 DOI: 10.1101/2024.01.12.575396  0.423
2023 Rebbeck T, Janivara R, Chen W, Hazra U, Baichoo S, Agalliu I, Kachambwa P, Simonti C, Brown L, Tambe S, Kim M, Harlemon M, Jalloh M, Muzondiwa D, Naidoo D, ... ... Lachance J, et al. Heterogeneous genetic architectures and evolutionary genomics of prostate cancer in Sub-Saharan Africa. Research Square. PMID 37886553 DOI: 10.21203/rs.3.rs-3378303/v1  0.425
2023 Pfennig A, Petersen LN, Kachambwa P, Lachance J. Evolutionary genetics and admixture in African populations. Genome Biology and Evolution. PMID 36987563 DOI: 10.1093/gbe/evad054  0.455
2022 Dyson CJ, Pfennig A, Ariano-Sánchez D, Lachance J, Mendelson Iii JR, Goodisman MAD. Genome of the endangered Guatemalan Beaded Lizard, Heloderma charlesbogerti, reveals evolutionary relationships of squamates and declines in effective population sizes. G3 (Bethesda, Md.). 12. PMID 36226801 DOI: 10.1093/g3journal/jkac276  0.359
2022 Pfennig A, Lachance J. Hybrid fitness effects modify fixation probabilities of introgressed alleles. G3 (Bethesda, Md.). PMID 35536195 DOI: 10.1093/g3journal/jkac113  0.357
2021 Quiver MH, Lachance J. Adaptive eQTLs reveal the evolutionary impacts of pleiotropy and tissue-specificity while contributing to health and disease. Hgg Advances. 3: 100083. PMID 35047867 DOI: 10.1016/j.xhgg.2021.100083  0.31
2021 Lachance J. Beyond Stamp Collecting: Evolutionary and Functional Genomics Advance Our Understanding of Cancer Biology. Cancer Research. 81: 1637-1638. PMID 34003790 DOI: 10.1158/0008-5472.CAN-21-0146  0.306
2020 Harlemon M, Ajayi O, Kachambwa P, Kim MS, Simonti CN, Quiver MH, Petersen DC, Mittal A, Fernandez PW, Hsing AW, Baichoo S, Agalliu I, Jalloh M, Gueye SM, Snyper NYF, ... ... Lachance J, et al. A custom genotyping array reveals population-level heterogeneity for the genetic risks of prostate cancer and other cancers in Africa. Cancer Research. PMID 32393663 DOI: 10.1158/0008-5472.CAN-19-2165  0.411
2019 Lachance J, Harlemon M, Kachambwa P, Ajayi O, Kim M, Adams M, Pugh E, Peterson L, Rebbeck T. Abstract 2410: Development of a custom genotyping platform and genetic prediction of prostate cancer risks in sub-Saharan Africa Epidemiology. DOI: 10.1158/1538-7445.Sabcs18-2410  0.323
2019 Lachance J. Echoes of the neutralist‐selectionist debate in an era of population genomics Evolution. 73: 860-861. DOI: 10.1111/Evo.13703  0.442
2018 Kim MS, Patel KP, Teng AK, Berens AJ, Lachance J. Genetic disease risks can be misestimated across global populations. Genome Biology. 19: 179. PMID 30424772 DOI: 10.1186/s13059-018-1561-7  0.491
2018 Hey J, Chung Y, Sethuraman A, Lachance J, Tishkoff S, Sousa VC, Wang Y. Phylogeny Estimation by Integration over Isolation with Migration Models. Molecular Biology and Evolution. PMID 30137463 DOI: 10.1093/Molbev/Msy162  0.626
2018 Rishishwar L, Wang L, Wang J, Yi SV, Lachance J, King Jordan I. Evidence for positive selection on recent human transposable element insertions. Gene. PMID 29953920 DOI: 10.1016/J.Gene.2018.06.077  0.519
2018 Lachance J, Berens AJ, Hansen MEB, Teng AK, Tishkoff SA, Rebbeck TR. Genetic hitchhiking and population bottlenecks contribute to prostate cancer disparities in men of African descent. Cancer Research. PMID 29438991 DOI: 10.1158/0008-5472.Can-17-1550  0.658
2017 Berens AJ, Cooper TL, Lachance J. The Genomic Health of Ancient Hominins. Human Biology. 89: 7-19. PMID 29285967 DOI: 10.13110/humanbiology.89.1.01  0.436
2017 Lachance J, Berens A, Hansen M, Teng A, Tishkoff S, Rebbeck T. Abstract A33: Population and evolutionary genomics of prostate cancer-associated variants: implications for health disparities in men of African descent Cancer Research. 77. DOI: 10.1158/1538-7445.Newfront17-A33  0.634
2016 Pagani L, Lawson DJ, Jagoda E, Mörseburg A, Eriksson A, Mitt M, Clemente F, Hudjashov G, DeGiorgio M, Saag L, Wall JD, Cardona A, Mägi R, Sayres MA, Kaewert S, ... ... Lachance J, et al. Genomic analyses inform on migration events during the peopling of Eurasia. Nature. PMID 27654910 DOI: 10.1038/Nature19792  0.681
2016 Hsieh P, Woerner AE, Wall JD, Lachance J, Tishkoff SA, Gutenkunst RN, Hammer MF. Corrigendum: Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies. Genome Research. 26: 717.1. PMID 27197244 DOI: 10.1101/Gr.206524.116  0.603
2016 Hsieh P, Woerner AE, Wall JD, Lachance J, Tishkoff SA, Gutenkunst RN, Hammer MF. Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies. Genome Research. PMID 26888264 DOI: 10.1101/Gr.196634.115  0.673
2016 Hsieh P, Veeramah KR, Lachance J, Tishkoff SA, Wall JD, Hammer MF, Gutenkunst RN. Whole-genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under positive natural selection. Genome Research. PMID 26888263 DOI: 10.1101/Gr.192971.115  0.666
2015 Karmin M, Saag L, Vicente M, Wilson Sayres MA, Järve M, Talas UG, Rootsi S, Ilumäe AM, Mägi R, Mitt M, Pagani L, Puurand T, Faltyskova Z, Clemente F, Cardona A, ... ... Lachance J, et al. A recent bottleneck of Y chromosome diversity coincides with a global change in culture. Genome Research. 25: 459-66. PMID 25770088 DOI: 10.1101/Gr.186684.114  0.612
2014 Lachance J, Tishkoff SA. Biased gene conversion skews allele frequencies in human populations, increasing the disease burden of recessive alleles. American Journal of Human Genetics. 95: 408-20. PMID 25279983 DOI: 10.1016/J.Ajhg.2014.09.008  0.687
2013 Lachance J, Tishkoff SA. Population Genomics of Human Adaptation. Annual Review of Ecology, Evolution, and Systematics. 44: 123-143. PMID 25383060 DOI: 10.1146/Annurev-Ecolsys-110512-135833  0.643
2013 Wang S, Lachance J, Tishkoff SA, Hey J, Xing J. Apparent variation in Neanderthal admixture among African populations is consistent with gene flow from Non-African populations. Genome Biology and Evolution. 5: 2075-81. PMID 24162011 DOI: 10.1093/Gbe/Evt160  0.651
2013 Lachance J, Jung L, True JR. Genetic background and GxE interactions modulate the penetrance of a naturally occurring wing mutation in Drosophila melanogaster. G3 (Bethesda, Md.). 3: 1893-901. PMID 24002866 DOI: 10.1534/g3.113.007831  0.652
2013 Lachance J, Tishkoff SA. SNP ascertainment bias in population genetic analyses: why it is important, and how to correct it. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 780-6. PMID 23836388 DOI: 10.1002/Bies.201300014  0.648
2012 Pickrell JK, Patterson N, Barbieri C, Berthold F, Gerlach L, Güldemann T, Kure B, Mpoloka SW, Nakagawa H, Naumann C, Lipson M, Loh PR, Lachance J, Mountain J, Bustamante CD, et al. The genetic prehistory of southern Africa. Nature Communications. 3: 1143. PMID 23072811 DOI: 10.1038/Ncomms2140  0.684
2012 Johnson NA, Lachance J. The genetics of sex chromosomes: evolution and implications for hybrid incompatibility. Annals of the New York Academy of Sciences. 1256: E1-22. PMID 23025408 DOI: 10.1111/j.1749-6632.2012.06748.x  0.308
2012 Lachance J, Vernot B, Elbers CC, Ferwerda B, Froment A, Bodo JM, Lema G, Fu W, Nyambo TB, Rebbeck TR, Zhang K, Akey JM, Tishkoff SA. Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers. Cell. 150: 457-69. PMID 22840920 DOI: 10.1016/J.Cell.2012.07.009  0.672
2011 Lachance J, Johnson NA, True JR. The population genetics of X-autosome synthetic lethals and steriles. Genetics. 189: 1011-27. PMID 21900269 DOI: 10.1534/genetics.111.131276  0.664
2010 Lachance J. Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations. Bmc Medical Genomics. 3: 57. PMID 21143973 DOI: 10.1186/1755-8794-3-57  0.401
2010 Lachance J, True JR. X-autosome incompatibilities in Drosophila melanogaster: tests of Haldane's rule and geographic patterns within species. Evolution; International Journal of Organic Evolution. 64: 3035-46. PMID 20455929 DOI: 10.1111/j.1558-5646.2010.01028.x  0.668
2009 Lachance J. Inbreeding, pedigree size, and the most recent common ancestor of humanity. Journal of Theoretical Biology. 261: 238-47. PMID 19679139 DOI: 10.1016/j.jtbi.2009.08.006  0.414
2009 Lachance J. Detecting selection-induced departures from Hardy-Weinberg proportions. Genetics, Selection, Evolution : Gse. 41: 15. PMID 19284519 DOI: 10.1186/1297-9686-41-15  0.415
2008 Lachance J. A fundamental relationship between genotype frequencies and fitnesses. Genetics. 180: 1087-93. PMID 18780726 DOI: 10.1534/genetics.108.093518  0.404
2008 Yukilevich R, Lachance J, Aoki F, True JR. Long-term adaptation of epistatic genetic networks. Evolution; International Journal of Organic Evolution. 62: 2215-35. PMID 18564374 DOI: 10.1111/j.1558-5646.2008.00445.x  0.723
2008 Yukilevich R, Lachance J, Aoki F, 1 JR. Long-term adaptation of epistatic genetic networks (Evolution (2008)) Evolution. 62: 2951. DOI: 10.1111/j.1558-5646.2008.00512.x  0.691
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