| Year |
Citation |
Score |
| 2024 |
Kelly RDW, Stengel KR, Chandru A, Johnson LC, Hiebert SW, Cowley SM. Histone deacetylases maintain expression of the pluripotent gene network via recruitment of RNA polymerase II to coding and noncoding loci. Genome Research. PMID 38290976 DOI: 10.1101/gr.278050.123 |
0.331 |
|
| 2023 |
Sroka MW, Skopelitis D, Vermunt MW, Preall JB, El Demerdash O, de Almeida LMN, Chang K, Utama R, Gryder B, Caligiuri G, Ren D, Nalbant B, Milazzo JP, Tuveson DA, Dobin A, ... Hiebert SW, et al. Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303859120. PMID 37639593 DOI: 10.1073/pnas.2303859120 |
0.326 |
|
| 2022 |
Zhang S, Wang J, Liu Q, McDonald WH, Bomber ML, Layden HM, Ellis J, Borinstein SC, Hiebert SW, Stengel KR. PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, and RNA polymerase pause release at select gene targets. Molecular Cell. PMID 36395771 DOI: 10.1016/j.molcel.2022.10.025 |
0.307 |
|
| 2022 |
Brown RE, Jacobse J, Anant SA, Blunt KM, Chen B, Vega PN, Jones CT, Pilat JM, Revetta F, Gorby AH, Stengel KR, Choksi YA, Palin K, Piazuelo MB, Washington MK, ... ... Hiebert SW, et al. MTG16 (CBFA2T3) regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors. Jci Insight. PMID 35503250 DOI: 10.1172/jci.insight.153045 |
0.315 |
|
| 2020 |
Stengel KR, Ellis JD, Spielman CL, Bomber ML, Hiebert SW. Definition of a small core transcriptional circuit regulated by AML1-ETO. Molecular Cell. PMID 33382982 DOI: 10.1016/j.molcel.2020.12.005 |
0.37 |
|
| 2020 |
Johnston G, Ramsey H, Liu Q, Wang J, Stengel KR, Sampathi S, Acharya P, Arrate M, Stubbs MC, Burn T, Savona MR, Hiebert SW. Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia. Gene. 144758. PMID 32422235 DOI: 10.1016/J.Gene.2020.144758 |
0.454 |
|
| 2020 |
Brown RE, Anant SA, Parang B, Short SP, Revetta FL, Choksi YA, Lau KS, Washington K, Brandt SJ, Davé UP, Hiebert S, Williams CS. 1108 A SINGLE RESIDUE IN MYELOID TRANSLOCATION GENE ON CHROMOSOME 16 (MTG16P209T) REGULATES EPITHELIAL RESPONSE TO INJURY AND INFLAMMATORY TUMORIGENESIS Gastroenterology. 158: S-215-S-216. DOI: 10.1016/S0016-5085(20)31230-0 |
0.331 |
|
| 2019 |
Dávalos-Salas M, Montgomery MK, Reehorst CM, Nightingale R, Ng I, Anderton H, Al-Obaidi S, Lesmana A, Scott CM, Ioannidis P, Kalra H, Keerthikumar S, Tögel L, Rigopoulos A, Gong SJ, ... ... Hiebert S, et al. Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity. Nature Communications. 10: 5291. PMID 31757939 DOI: 10.1038/S41467-019-13180-8 |
0.382 |
|
| 2019 |
Stengel KR, Bhaskara S, Wang J, Liu Q, Ellis JD, Sampathi S, Hiebert SW. Histone deacetylase 3 controls a transcriptional network required for B cell maturation. Nucleic Acids Research. PMID 31586401 DOI: 10.1093/Nar/Gkz816 |
0.441 |
|
| 2019 |
Aho ER, Wang J, Gogliotti RD, Howard GC, Phan J, Acharya P, Macdonald JD, Cheng K, Lorey SL, Lu B, Wenzel S, Foshage AM, Alvarado J, Wang F, Shaw JG, ... ... Hiebert SW, et al. Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Reports. 26: 2916-2928.e13. PMID 30865883 DOI: 10.1016/J.Celrep.2019.02.047 |
0.365 |
|
| 2019 |
Short SP, Barrett CW, Stengel KR, Revetta FL, Choksi YA, Coburn LA, Lintel MK, McDonough EM, Washington MK, Wilson KT, Prokhortchouk E, Chen X, Hiebert SW, Reynolds AB, Williams CS. Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma. Oncogene. PMID 30858547 DOI: 10.1038/S41388-019-0777-7 |
0.407 |
|
| 2019 |
Sampathi S, Acharya P, Zhao Y, Wang J, Stengel KR, Liu Q, Savona MR, Hiebert SW. The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5' and 3' ends of genes. Nucleic Acids Research. PMID 30805632 DOI: 10.1093/Nar/Gkz127 |
0.361 |
|
| 2019 |
Brown RE, Parang B, Short SP, Thompson JJ, Pilat JM, Vachharajani NB, Anant SA, Mittal MK, Bradley AM, Acharya P, Revetta FL, Washington K, Piazuelo MB, Shroyer NF, Lau KS, ... ... Hiebert S, et al. 993 – Myeloid Translocation Gene on Chromosome 16 (MTG16) is a Transcriptional Co-Repressor that Regulates Epithelial Response to Injury Via Homology Regions Nhr1 and Nhr3 Gastroenterology. 156: S-211. DOI: 10.1016/S0016-5085(19)37325-1 |
0.386 |
|
| 2018 |
Zhang S, Zhao Y, Heaster TM, Fischer MA, Stengel KR, Zhou X, Ramsey H, Zhou MM, Savona MR, Skala MC, Hiebert SW. BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML. Journal of Cellular Biochemistry. PMID 30417424 DOI: 10.1002/Jcb.28005 |
0.444 |
|
| 2018 |
Wang J, Zhao Y, Zhou X, Hiebert SW, Liu Q, Shyr Y. Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation. Bmc Genomics. 19: 633. PMID 30139328 DOI: 10.1186/S12864-018-5016-Z |
0.357 |
|
| 2018 |
Ramsey H, Zhang S, Zhao Y, Fischer MA, Gorska AE, Arrate M, Fuller L, Greenwood D, Stubbs MC, Liu P, Rathmell JC, Hiebert S, Savona MR. The BET Inhibitor INCB054329 Primes AML Cells for Venetoclax-Induced Apoptosis Blood. 132: 4074-4074. DOI: 10.1182/Blood-2018-99-111393 |
0.432 |
|
| 2017 |
McDonough EM, Barrett CW, Parang B, Mittal MK, Smith JJ, Bradley AM, Choksi YA, Coburn LA, Short SP, Thompson JJ, Zhang B, Poindexter SV, Fischer MA, Chen X, Li J, ... ... Hiebert SW, et al. MTG16 is a tumor suppressor in colitis-associated carcinoma. Jci Insight. 2. PMID 28814670 DOI: 10.1172/Jci.Insight.78210 |
0.371 |
|
| 2017 |
Kim HG, LeGrand J, Swindle CS, Nick HJ, Oster RA, Chen D, Purohit-Ghelani S, Cotta CV, Ko R, Gartland L, Reddy V, Hiebert SW, Friedman AD, Klug CA. The assembly competence domain is essential for inv(16)-associated acute myeloid leukemia. Leukemia. PMID 28751774 DOI: 10.1038/Leu.2017.236 |
0.33 |
|
| 2017 |
Stengel KR, Barnett KR, Wang J, Liu Q, Hodges E, Hiebert SW, Bhaskara S. Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739911 DOI: 10.1073/Pnas.1701610114 |
0.419 |
|
| 2017 |
Ferrari A, Longo R, Fiorino E, Silva R, Mitro N, Cermenati G, Gilardi F, Desvergne B, Andolfo A, Magagnotti C, Caruso D, Fabiani E, Hiebert SW, Crestani M. HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning. Nature Communications. 8: 93. PMID 28733645 DOI: 10.1038/S41467-017-00182-7 |
0.309 |
|
| 2016 |
Jiang Y, Ortega-Molina A, Geng H, Ying HY, Hatzi K, Parsa S, McNally D, Wang L, Doane AS, Agirre Ena X, Teater M, Meydan C, Li Z, Poloway D, Wang S, ... ... Hiebert SW, et al. CREBBP Inactivation Promotes the Development of HDAC3 Dependent Lymphomas. Cancer Discovery. PMID 27733359 DOI: 10.1158/2159-8290.Cd-16-0975 |
0.435 |
|
| 2016 |
Cho SH, Raybuck AL, Stengel K, Wei M, Beck TC, Volanakis E, Thomas JW, Hiebert S, Haase VH, Boothby MR. Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system. Nature. PMID 27501247 DOI: 10.1038/Nature19334 |
0.372 |
|
| 2016 |
Zhao Y, Liu Q, Acharya P, Stengel KR, Sheng Q, Zhou X, Kwak H, Fischer MA, Bradner JE, Strickland SA, Mohan SR, Savona MR, Venters BJ, Zhou MM, Lis JT, ... Hiebert SW, et al. High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML. Cell Reports. PMID 27498870 DOI: 10.1016/J.Celrep.2016.07.032 |
0.435 |
|
| 2016 |
Parang B, Bradley AM, Mittal MK, Short SP, Thompson JJ, Barrett CW, Naik RD, Bilotta AJ, Washington MK, Revetta FL, Smith JJ, Chen X, Wilson KT, Hiebert SW, Williams CS. Myeloid translocation genes differentially regulate colorectal cancer programs. Oncogene. PMID 27270437 DOI: 10.1038/Onc.2016.167 |
0.446 |
|
| 2016 |
Adams CM, Hiebert SW, Eischen CM. Abstract A24: HDAC inhibition unmasks a microRNA-mediated mechanism of tumor suppression Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-A24 |
0.36 |
|
| 2015 |
Adams CM, Hiebert SW, Eischen CM. Myc induces miRNA-mediated apoptosis in response to HDAC inhibition in hematologic malignancies. Cancer Research. PMID 26676759 DOI: 10.1158/0008-5472.Can-15-1751 |
0.376 |
|
| 2015 |
Stengel KR, Zhao Y, Klus NJ, Kaiser JF, Gordy LE, Joyce S, Hiebert SW, Summers AR. Histone Deacetylase 3 Is Required for Efficient T Cell Development. Molecular and Cellular Biology. 35: 3854-65. PMID 26324326 DOI: 10.1128/Mcb.00706-15 |
0.37 |
|
| 2015 |
Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW. FOXP3⁺ regulatory T cell development and function require histone/protein deacetylase 3. The Journal of Clinical Investigation. 125: 3304. PMID 26237045 DOI: 10.1172/JCI83084 |
0.318 |
|
| 2015 |
Hsu FC, Belmonte PJ, Constans MM, Chen MW, McWilliams DC, Hiebert SW, Shapiro VS. Histone Deacetylase 3 Is Required for T Cell Maturation. Journal of Immunology (Baltimore, Md. : 1950). PMID 26163592 DOI: 10.4049/Jimmunol.1500435 |
0.382 |
|
| 2015 |
Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, ... ... Hiebert SW, et al. Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells. Cell Stem Cell. 16: 477-87. PMID 25957903 DOI: 10.1016/J.Stem.2015.04.008 |
0.337 |
|
| 2015 |
Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW. FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3. The Journal of Clinical Investigation. 125: 1111-23. PMID 25642770 DOI: 10.1172/Jci77088 |
0.386 |
|
| 2015 |
Poindexter SV, Reddy VK, Mittal MK, Williams AM, Washington MK, Harris E, Mah A, Hiebert SW, Singh K, Chaturvedi R, Wilson KT, Lund PK, Williams CS. Transcriptional corepressor MTG16 regulates small intestinal crypt proliferation and crypt regeneration after radiation-induced injury. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G562-71. PMID 25573176 DOI: 10.1152/Ajpgi.00253.2014 |
0.391 |
|
| 2015 |
Parang B, Rosenblatt D, Williams AD, Washington MK, Revetta F, Short SP, Reddy VK, Hunt A, Shroyer NF, Engel ME, Hiebert SW, Williams CS. The transcriptional corepressor MTGR1 regulates intestinal secretory lineage allocation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 786-95. PMID 25398765 DOI: 10.1096/Fj.14-254284 |
0.801 |
|
| 2015 |
Stengel KR, Hiebert SW. Class I HDACs Affect DNA Replication, Repair, and Chromatin Structure: Implications for Cancer Therapy. Antioxidants & Redox Signaling. 23: 51-65. PMID 24730655 DOI: 10.1089/Ars.2014.5915 |
0.354 |
|
| 2015 |
Zhao Y, Liu P, Scherle P, Huber R, Savona MR, Hiebert S. High Resolution Mapping of Active RNA Polymerases Identifies KIT As a Target of BET Inhibitors in t(8;21) AML Blood. 126: 1225-1225. DOI: 10.1182/Blood.V126.23.1225.1225 |
0.457 |
|
| 2015 |
Acharya P, Hiebert SW. Abstract A26: Cancer-associated mutations impair the functional association of ETO/MTG family members with E proteins. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A26 |
0.451 |
|
| 2014 |
Ha K, Fiskus W, Choi DS, Bhaskara S, Cerchietti L, Devaraj SG, Shah B, Sharma S, Chang JC, Melnick AM, Hiebert S, Bhalla KN. Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells. Oncotarget. 5: 5637-50. PMID 25026298 DOI: 10.18632/Oncotarget.2154 |
0.374 |
|
| 2014 |
Ghosh HS, Ceribelli M, Matos I, Lazarovici A, Bussemaker HJ, Lasorella A, Hiebert SW, Liu K, Staudt LM, Reizis B. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2. The Journal of Experimental Medicine. 211: 1623-35. PMID 24980046 DOI: 10.1084/Jem.20132121 |
0.411 |
|
| 2013 |
Yan L, Womack B, Wotton D, Guo Y, Shyr Y, Davé U, Li C, Hiebert S, Brandt S, Hamid R. Tgif1 regulates quiescence and self-renewal of hematopoietic stem cells. Molecular and Cellular Biology. 33: 4824-33. PMID 24100014 DOI: 10.1128/Mcb.01076-13 |
0.392 |
|
| 2013 |
Summers AR, Fischer MA, Stengel KR, Zhao Y, Kaiser JF, Wells CE, Hunt A, Bhaskara S, Luzwick JW, Sampathi S, Chen X, Thompson MA, Cortez D, Hiebert SW. HDAC3 is essential for DNA replication in hematopoietic progenitor cells. The Journal of Clinical Investigation. 123: 3112-23. PMID 23921131 DOI: 10.1172/Jci60806 |
0.789 |
|
| 2013 |
Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM, Kormaksson M, MacKerell AD, Xue F, Mason CE, Hiebert SW, et al. A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters. Cell Reports. 4: 578-88. PMID 23911289 DOI: 10.1016/J.Celrep.2013.06.016 |
0.458 |
|
| 2013 |
Wells CE, Bhaskara S, Stengel KR, Zhao Y, Sirbu B, Chagot B, Cortez D, Khabele D, Chazin WJ, Cooper A, Jacques V, Rusche J, Eischen CM, McGirt LY, Hiebert SW. Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. Plos One. 8: e68915. PMID 23894374 DOI: 10.1371/Journal.Pone.0068915 |
0.424 |
|
| 2013 |
Thapa P, Das J, McWilliams D, Shapiro M, Sundsbak R, Nelson-Holte M, Tangen S, Anderson J, Desiderio S, Hiebert S, Sant'angelo DB, Shapiro VS. The transcriptional repressor NKAP is required for the development of iNKT cells. Nature Communications. 4: 1582. PMID 23481390 DOI: 10.1038/Ncomms2580 |
0.399 |
|
| 2013 |
Ziesché E, Kettner-Buhrow D, Weber A, Wittwer T, Jurida L, Soelch J, Müller H, Newel D, Kronich P, Schneider H, Dittrich-Breiholz O, Bhaskara S, Hiebert SW, Hottiger MO, Li H, et al. The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB. Nucleic Acids Research. 41: 90-109. PMID 23087373 DOI: 10.1093/Nar/Gks916 |
0.412 |
|
| 2013 |
Williams CS, Bradley AM, Chaturvedi R, Singh K, Piazuelo MB, Chen X, McDonough EM, Schwartz DA, Brown CT, Allaman MM, Coburn LA, Horst SN, Beaulieu DB, Choksi YA, Washington MK, ... ... Hiebert SW, et al. MTG16 contributes to colonic epithelial integrity in experimental colitis. Gut. 62: 1446-55. PMID 22833394 DOI: 10.1136/Gutjnl-2011-301439 |
0.357 |
|
| 2013 |
Chatzi K, Jiang Y, Huang C, Zumbo P, Bhaskara S, MacKerell AD, Xue F, Mason CE, Hiebert SW, Cerchietti L, Bardwell VJ, Elemento O, Ari M. Abstract B14: A biochemical basis for toggling enhancers from the active to poised state in B-cells Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B14 |
0.468 |
|
| 2013 |
Khabele D, Wilson AJ, Saskowski J, Hiebert SW. Abstract B52: The bromodomain inhibitor JQ1 enhances cisplatin-mediated cytotoxicity in ovarian cancer cells Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-B52 |
0.362 |
|
| 2013 |
Parang B, Reddy VK, Rosenblatt D, Williams A, Hunt A, Revetta F, Lo Y, Washington K, Engel M, Hiebert SW, Shroyer NF, Williams CS. 130 MTGR1 Is Required for Gsi-Induced Paneth Cell Differentiation Gastroenterology. 144: S-31. DOI: 10.1016/S0016-5085(13)60110-9 |
0.768 |
|
| 2012 |
Barrett CW, Smith JJ, Lu LC, Markham N, Stengel KR, Short SP, Zhang B, Hunt AA, Fingleton BM, Carnahan RH, Engel ME, Chen X, Beauchamp RD, Wilson KT, Hiebert SW, et al. Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters. Plos One. 7: e51205. PMID 23251453 DOI: 10.1371/Journal.Pone.0051205 |
0.803 |
|
| 2012 |
Chen X, Barozzi I, Termanini A, Prosperini E, Recchiuti A, Dalli J, Mietton F, Matteoli G, Hiebert S, Natoli G. Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 109: E2865-74. PMID 22802645 DOI: 10.1073/Pnas.1121131109 |
0.4 |
|
| 2012 |
Fischer MA, Moreno-Miralles I, Hunt A, Chyla BJ, Hiebert SW. Myeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence. The Embo Journal. 31: 1494-505. PMID 22266796 DOI: 10.1038/Emboj.2011.500 |
0.792 |
|
| 2012 |
Ghosh HS, Liu K, Hiebert S, Reizis B. Eto2/MTG16 Regulates E-Protein Activity and Subset Specification in Dendritic Cell Development Blood. 120: 1229-1229. DOI: 10.1182/Blood.V120.21.1229.1229 |
0.48 |
|
| 2011 |
Wilson AJ, Holson E, Wagner F, Zhang YL, Fass DM, Haggarty SJ, Bhaskara S, Hiebert SW, Schreiber SL, Khabele D. The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells. Cancer Biology & Therapy. 12: 484-93. PMID 21738006 DOI: 10.4161/Cbt.12.6.15956 |
0.322 |
|
| 2011 |
Sirbu BM, Couch FB, Feigerle JT, Bhaskara S, Hiebert SW, Cortez D. Analysis of protein dynamics at active, stalled, and collapsed replication forks. Genes & Development. 25: 1320-7. PMID 21685366 DOI: 10.1101/Gad.2053211 |
0.386 |
|
| 2011 |
Hunt A, Fischer M, Engel ME, Hiebert SW. Mtg16/Eto2 contributes to murine T-cell development. Molecular and Cellular Biology. 31: 2544-51. PMID 21536648 DOI: 10.1128/Mcb.01458-10 |
0.798 |
|
| 2011 |
Bhaskara S, Hiebert SW. Role for histone deacetylase 3 in maintenance of genome stability. Cell Cycle (Georgetown, Tex.). 10: 727-8. PMID 21311228 DOI: 10.4161/Cc.10.5.14866 |
0.476 |
|
| 2011 |
Barrett CW, Fingleton B, Williams A, Ning W, Fischer MA, Washington MK, Chaturvedi R, Wilson KT, Hiebert SW, Williams CS. MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model. Cancer Research. 71: 1302-12. PMID 21303973 DOI: 10.1158/0008-5472.Can-10-3317 |
0.407 |
|
| 2010 |
Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S, Yenamandra A, Locke K, Yuan JL, Bonine-Summers AR, Wells CE, Kaiser JF, Washington MK, Zhao Z, Wagner FF, ... ... Hiebert SW, et al. Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell. 18: 436-47. PMID 21075309 DOI: 10.1016/J.Ccr.2010.10.022 |
0.732 |
|
| 2010 |
Razidlo DF, Whitney TJ, Casper ME, McGee-Lawrence ME, Stensgard BA, Li X, Secreto FJ, Knutson SK, Hiebert SW, Westendorf JJ. Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat. Plos One. 5: e11492. PMID 20628553 DOI: 10.1371/Journal.Pone.0011492 |
0.711 |
|
| 2010 |
Huang F, Chandrasekharan MB, Chen YC, Bhaskara S, Hiebert SW, Sun ZW. The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation. The Journal of Biological Chemistry. 285: 24548-61. PMID 20538609 DOI: 10.1074/Jbc.M110.117333 |
0.437 |
|
| 2010 |
Compton LA, Hiebert SW. Anticancer therapy SMRT-ens up: targeting the BCL6-SMRT interaction in B cell lymphoma. Cancer Cell. 17: 315-6. PMID 20385356 DOI: 10.1016/J.Ccr.2010.03.012 |
0.365 |
|
| 2010 |
Engel ME, Hiebert SW. Proleukemic RUNX1 and CBFbeta mutations in the pathogenesis of acute leukemia. Cancer Treatment and Research. 145: 127-47. PMID 20306249 DOI: 10.1007/978-0-387-69259-3_8 |
0.412 |
|
| 2010 |
Engel ME, Nguyen HN, Mariotti J, Hunt A, Hiebert SW. Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification. Molecular and Cellular Biology. 30: 1852-63. PMID 20123979 DOI: 10.1128/Mcb.01342-09 |
0.806 |
|
| 2010 |
Wilson AJ, Holson E, Bhaskara S, Carlise J, Schreiber SL, Hiebert SW, Khabele D. Abstract 2985: DNA-damage related histone marks can distinguish the anti-tumor effects of established and novel histone deacetylase inhibitors in ovarian cancer cells Cancer Research. 70: 2985-2985. DOI: 10.1158/1538-7445.Am10-2985 |
0.341 |
|
| 2009 |
Cai Y, Xu Z, Xie J, Ham AJ, Koury MJ, Hiebert SW, Brandt SJ. Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors. Biochemical and Biophysical Research Communications. 390: 295-301. PMID 19799863 DOI: 10.1016/J.Bbrc.2009.09.111 |
0.523 |
|
| 2009 |
Yan M, Ahn EY, Hiebert SW, Zhang DE. RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis. Blood. 113: 883-6. PMID 19036704 DOI: 10.1182/Blood-2008-04-153742 |
0.474 |
|
| 2009 |
Engel ME, Nguyen H, Mariotti J, Hunt AA, Hiebert S. Myeloid Translocation Gene (MTG)-16 Binds Intracellular Domains of Notch Receptors to Coordinate Notch-Dependent Cell Fate Specification. Blood. 114: 257-257. DOI: 10.1182/Blood.V114.22.257.257 |
0.807 |
|
| 2008 |
Chyla BJ, Moreno-Miralles I, Steapleton MA, Thompson MA, Bhaskara S, Engel M, Hiebert SW. Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation. Molecular and Cellular Biology. 28: 6234-47. PMID 18710942 DOI: 10.1128/Mcb.00404-08 |
0.485 |
|
| 2008 |
Farmer TE, Williams CS, Washington MK, Hiebert SW. Inactivation of the p19(ARF) tumor suppressor affects intestinal epithelial cell proliferation and integrity. Journal of Cellular Biochemistry. 104: 2228-40. PMID 18442038 DOI: 10.1002/Jcb.21779 |
0.779 |
|
| 2008 |
Bhaskara S, Chyla BJ, Amann JM, Knutson SK, Cortez D, Sun ZW, Hiebert SW. Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control. Molecular Cell. 30: 61-72. PMID 18406327 DOI: 10.1016/J.Molcel.2008.02.030 |
0.739 |
|
| 2008 |
Knutson SK, Chyla BJ, Amann JM, Bhaskara S, Huppert SS, Hiebert SW. Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks. The Embo Journal. 27: 1017-28. PMID 18354499 DOI: 10.1038/Emboj.2008.51 |
0.737 |
|
| 2008 |
Moore AC, Amann JM, Williams CS, Tahinci E, Farmer TE, Martinez JA, Yang G, Luce KS, Lee E, Hiebert SW. Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription. Molecular and Cellular Biology. 28: 977-87. PMID 18039847 DOI: 10.1128/Mcb.01242-07 |
0.815 |
|
| 2008 |
Hanson CA, Wood LD, Hiebert SW. Cellular stress triggers TEL nuclear export via two genetically separable pathways. Journal of Cellular Biochemistry. 104: 488-98. PMID 18022807 DOI: 10.1002/Jcb.21637 |
0.335 |
|
| 2008 |
Steapleton MA, Moreno I, Chyla B, Hiebert S. MTG16, a Target of the T(16;21) in Acute Myeloid Leukemia, Is Required for Hematopoietic Stem and Progenitor Cell Functions Blood. 112: 609-609. DOI: 10.1182/blood.v112.11.609.609 |
0.335 |
|
| 2008 |
Hunt AA, Steapleton MA, Moreno I, Hiebert S. Myeloid Translocation Gene 16 (MTG16) Regulates Lymphopoiesis Blood. 112: 2466-2466. DOI: 10.1182/blood.v112.11.2466.2466 |
0.8 |
|
| 2007 |
Yang G, Thompson MA, Brandt SJ, Hiebert SW. Histone deacetylase inhibitors induce the degradation of the t(8;21) fusion oncoprotein. Oncogene. 26: 91-101. PMID 16799637 DOI: 10.1038/Sj.Onc.1209760 |
0.413 |
|
| 2006 |
Martinez JA, Williams CS, Amann JM, Ellis TC, Moreno-Miralles I, Washington MK, Gregoli P, Hiebert SW. Deletion of Mtgr1 sensitizes the colonic epithelium to dextran sodium sulfate-induced colitis. Gastroenterology. 131: 579-88. PMID 16890610 DOI: 10.1053/J.Gastro.2006.06.009 |
0.346 |
|
| 2006 |
Reed-Inderbitzin E, Moreno-Miralles I, Vanden-Eynden SK, Xie J, Lutterbach B, Durst-Goodwin KL, Luce KS, Irvin BJ, Cleary ML, Brandt SJ, Hiebert SW. RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription Oncogene. 25: 5777-5786. PMID 16652147 DOI: 10.1038/Sj.Onc.1209591 |
0.515 |
|
| 2005 |
Amann JM, Chyla BJ, Ellis TC, Martinez A, Moore AC, Franklin JL, McGhee L, Meyers S, Ohm JE, Luce KS, Ouelette AJ, Washington MK, Thompson MA, King D, Gautam S, ... ... Hiebert SW, et al. Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine. Molecular and Cellular Biology. 25: 9576-85. PMID 16227606 DOI: 10.1128/Mcb.25.21.9576-9585.2005 |
0.503 |
|
| 2005 |
Moreno-Miralles I, Pan L, Keates-Baleeiro J, Durst-Goodwin K, Yang C, Kim HG, Thompson MA, Klug CA, Cleveland JL, Hiebert SW. The inv(16) cooperates with ARF haploinsufficiency to induce acute myeloid leukemia. The Journal of Biological Chemistry. 280: 40097-103. PMID 16199529 DOI: 10.1074/Jbc.M506855200 |
0.404 |
|
| 2005 |
Linggi BE, Brandt SJ, Sun ZW, Hiebert SW. Translating the histone code into leukemia. Journal of Cellular Biochemistry. 96: 938-50. PMID 16167339 DOI: 10.1002/Jcb.20604 |
0.754 |
|
| 2005 |
Ice RJ, Wildonger J, Mann RS, Hiebert SW. Comment on "Nervy links protein kinase A to plexin-mediated semaphorin repulsion". Science (New York, N.Y.). 309: 558; author reply 55. PMID 16040690 DOI: 10.1126/Science.1108719 |
0.33 |
|
| 2005 |
Yang G, Khalaf W, van de Locht L, Jansen JH, Gao M, Thompson MA, van der Reijden BA, Gutmann DH, Delwel R, Clapp DW, Hiebert SW. Transcriptional repression of the Neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein. Molecular and Cellular Biology. 25: 5869-79. PMID 15988004 DOI: 10.1128/Mcb.25.14.5869-5879.2005 |
0.445 |
|
| 2005 |
Zhang L, D’Costa J, Kummalue T, Moreno I, Civin CI, Hiebert SW, Friedman AD. Mutational Analysis of the CBFβ-SMMHC Assembly Competence Domain Identifies a Surface Critical for Multimerization and Inhibition of RUNX1/AML1. Blood. 106: 2853-2853. DOI: 10.1182/Blood.V106.11.2853.2853 |
0.372 |
|
| 2005 |
Xie J, Hiebert SW, Koury MJ, Brandt SJ. RUNX1 Directly Regulates Band 3 Transcription. Blood. 106: 1735-1735. DOI: 10.1182/Blood.V106.11.1735.1735 |
0.47 |
|
| 2004 |
Durst KL, Hiebert SW. Role of RUNX family members in transcriptional repression and gene silencing. Oncogene. 23: 4220-4. PMID 15156176 DOI: 10.1038/Sj.Onc.1207122 |
0.822 |
|
| 2004 |
van Wijnen AJ, Stein GS, Gergen JP, Groner Y, Hiebert SW, Ito Y, Liu P, Neil JC, Ohki M, Speck N. Nomenclature for Runt-related (RUNX) proteins. Oncogene. 23: 4209-10. PMID 15156174 DOI: 10.1038/Sj.Onc.1207758 |
0.444 |
|
| 2004 |
Yang G, Khalaf W, van de Locht L, Jansen JH, van der Reijden BA, Müller-Tidow C, Delwel HR, Serve H, Clapp DW, Hiebert SW. Epigenetic regulation of tumor suppressors in t(8:21)-containing AML. Annals of Hematology. 83: 329-30. PMID 15052372 DOI: 10.1007/S00277-003-0841-8 |
0.507 |
|
| 2004 |
Müller-Tidow C, Steffen B, Cauvet T, Tickenbrock L, Ji P, Diederichs S, Sargin B, Köhler G, Stelljes M, Puccetti E, Ruthardt M, deVos S, Hiebert SW, Koeffler HP, Berdel WE, et al. Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells. Molecular and Cellular Biology. 24: 2890-904. PMID 15024077 DOI: 10.1128/Mcb.24.7.2890-2904.2004 |
0.517 |
|
| 2004 |
Moreno I, Pan L, Keates J, Kim H, Klug C, Hiebert S. Establishment of a Retroviral Mouse Model for inv(16)-Mediated Acute Myeloid Leukemia Suggests That the p14ARF Tumor Suppressor Is a Transcriptional Target for Repression by the inv(16) Fusion Protein. Blood. 104: 547-547. DOI: 10.1182/Blood.V104.11.547.547 |
0.487 |
|
| 2004 |
Cai Y, Xu Z, Xie J, Koury MJ, Hiebert SW, Brandt SJ. Proteomic Identification of TAL1/SCL-Interacting Proteins: ETO-2 and MTGR1 Interact with TAL1 in Erythroid Progenitors. Blood. 104: 357-357. DOI: 10.1182/Blood.V104.11.357.357 |
0.501 |
|
| 2004 |
Moore A, Tahinci E, Lee E, Hiebert S. RUNX1-ETO Stimulates Wnt Signaling by Inhibiting the Function of ETO Family Member Proteins. Blood. 104: 2554-2554. DOI: 10.1182/Blood.V104.11.2554.2554 |
0.452 |
|
| 2004 |
Yang G, Khalaf W, Clapp WD, Hiebert SW. Neurofibromatosis Type 1 (NF1), a Tumor Suppressor Gene, Is Synergistically Activated by RUNX1, C/EBPαa and ETS2 and Specifically Repressed by the T(8;21) Fusion Protein in Acute Myeloid Leukemia. Blood. 104: 2551-2551. DOI: 10.1182/Blood.V104.11.2551.2551 |
0.426 |
|
| 2004 |
Zhang L, Hiebert SW, Friedman AD. Multimerization and Corepression Mediated by the CBFβ-SMMHC Assembly Competence Domain Are Partially Separable and Corepression Is Required to Inhibit Core Binding Factor Activities. Blood. 104: 1972-1972. DOI: 10.1182/Blood.V104.11.1972.1972 |
0.46 |
|
| 2003 |
Irvin BJ, Wood LD, Wang L, Fenrick R, Sansam CG, Packham G, Kinch M, Yang E, Hiebert SW. TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL. The Journal of Biological Chemistry. 278: 46378-86. PMID 12960174 DOI: 10.1074/Jbc.M305189200 |
0.487 |
|
| 2003 |
Steffen B, Serve H, Berdel WE, Agrawal S, Linggi B, Büchner T, Hiebert SW, Müller-Tidow C. Specific protein redirection as a transcriptional therapy approach for t(8;21) leukemia. Proceedings of the National Academy of Sciences of the United States of America. 100: 8448-53. PMID 12819347 DOI: 10.1073/Pnas.1330293100 |
0.804 |
|
| 2003 |
Hiebert SW, Reed-Inderbitzin EF, Amann J, Irvin B, Durst K, Linggi B. The t(8;21) fusion protein contacts co-repressors and histone deacetylases to repress the transcription of the p14ARF tumor suppressor. Blood Cells, Molecules & Diseases. 30: 177-83. PMID 12732181 DOI: 10.1016/S1079-9796(03)00021-4 |
0.802 |
|
| 2003 |
Wood LD, Irvin BJ, Nucifora G, Luce KS, Hiebert SW. Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 100: 3257-62. PMID 12626745 DOI: 10.1073/Pnas.0637114100 |
0.485 |
|
| 2003 |
Durst KL, Lutterbach B, Kummalue T, Friedman AD, Hiebert SW. The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain. Molecular and Cellular Biology. 23: 607-19. PMID 12509458 DOI: 10.1128/Mcb.23.2.607-619.2003 |
0.814 |
|
| 2002 |
Barseguian K, Lutterbach B, Hiebert SW, Nickerson J, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins. Proceedings of the National Academy of Sciences of the United States of America. 99: 15434-9. PMID 12427969 DOI: 10.1073/Pnas.242588499 |
0.478 |
|
| 2002 |
King D, Yang G, Thompson MA, Hiebert SW. Loss of neurofibromatosis-1 and p19(ARF) cooperate to induce a multiple tumor phenotype. Oncogene. 21: 4978-82. PMID 12118376 DOI: 10.1038/Sj.Onc.1205632 |
0.31 |
|
| 2002 |
de Guzman CG, Warren AJ, Zhang Z, Gartland L, Erickson P, Drabkin H, Hiebert SW, Klug CA. Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation. Molecular and Cellular Biology. 22: 5506-17. PMID 12101243 DOI: 10.1128/Mcb.22.15.5506-5517.2002 |
0.407 |
|
| 2002 |
Linggi B, Müller-Tidow C, van de Locht L, Hu M, Nip J, Serve H, Berdel WE, van der Reijden B, Quelle DE, Rowley JD, Cleveland J, Jansen JH, Pandolfi PP, Hiebert SW. The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia. Nature Medicine. 8: 743-50. PMID 12091906 DOI: 10.1038/Nm726 |
0.781 |
|
| 2001 |
Eischen CM, Packham G, Nip J, Fee BE, Hiebert SW, Zambetti GP, Cleveland JL. Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1 Oncogene. 20: 6983-6993. PMID 11704823 DOI: 10.1038/Sj.Onc.1204892 |
0.391 |
|
| 2001 |
Hiebert SW, Lutterbach B, Durst K, Wang L, Linggi B, Wu S, Wood L, Amann J, King D, Hou Y. Mechanisms of transcriptional repression by the t(8;21)-, t(12;21)-, and inv(16)-encoded fusion proteins Cancer Chemotherapy and Pharmacology. 48. PMID 11587363 DOI: 10.1007/S002800100302 |
0.815 |
|
| 2001 |
Hiebert SW, Lutterbach B, Amann J. Role of co-repressors in transcriptional repression mediated by the t(8;21), t(16;21), t(12;21), and inv(16) fusion proteins Current Opinion in Hematology. 8: 197-200. PMID 11561155 DOI: 10.1097/00062752-200107000-00003 |
0.431 |
|
| 2001 |
Amann JM, Nip J, Strom DK, Lutterbach B, Harada H, Lenny N, Downing JR, Meyers S, Hiebert SW. ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain Molecular and Cellular Biology. 21: 6470-6483. PMID 11533236 DOI: 10.1128/Mcb.21.19.6470-6483.2001 |
0.509 |
|
| 2001 |
Wang L, Hiebert SW. TEL contacts multiple co-repressors and specifically associates with histone deacetylase-3 Oncogene. 20: 3716-3725. PMID 11439334 DOI: 10.1038/Sj.Onc.1204479 |
0.486 |
|
| 2001 |
Nip J, Strom DK, Eischen CM, Cleveland JL, Zambetti GP, Hiebert SW. E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation Oncogene. 20: 910-920. PMID 11314026 DOI: 10.1038/Sj.Onc.1204171 |
0.324 |
|
| 2001 |
Hiebert S. Differentiation or leukemia: is C/EBPalpha the answer? Nature Medicine. 7: 407-8. PMID 11283659 DOI: 10.1038/86461 |
0.382 |
|
| 2000 |
Meyers S, Hiebert SW. Alterations in subnuclear trafficking of nuclear regulatory factors in acute leukemia Journal of Cellular Biochemistry. Supplement. 93-98. PMID 11389537 DOI: 10.1002/1097-4644(2000)79:35+<93::Aid-Jcb1131>3.0.Co;2-4 |
0.481 |
|
| 2000 |
Nip J, Hiebert SW. Topoisomerase IIα mediates E2F-1-induced chemosensitivity and is a target for p53-mediated transcriptional repression Cell Biochemistry and Biophysics. 33: 199-207. PMID 11325040 DOI: 10.1385/Cbb:33:2:199 |
0.382 |
|
| 2000 |
Melnick A, Carlile GW, McConnell MJ, Polinger A, Hiebert SW, Licht JD. AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein. Blood. 96: 3939-47. PMID 11090081 DOI: 10.1182/Blood.V96.12.3939.H8003939_3939_3947 |
0.54 |
|
| 2000 |
Fenrick R, Wang L, Nip J, Amann JM, Rooney RJ, Walker-Daniels J, Crawford HC, Hulboy DL, Kinch MS, Matrisian LM, Hiebert SW. TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1. Molecular and Cellular Biology. 20: 5828-39. PMID 10913166 DOI: 10.1128/Mcb.20.16.5828-5839.2000 |
0.414 |
|
| 2000 |
Lutterbach B, Hiebert SW. Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation Gene. 245: 223-235. PMID 10717473 DOI: 10.1016/S0378-1119(00)00014-7 |
0.497 |
|
| 2000 |
Melnick AM, Westendorf JJ, Polinger A, Carlile GW, Arai S, Ball HJ, Lutterbach B, Hiebert SW, Licht JD. The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein Molecular and Cellular Biology. 20: 2075-2086. PMID 10688654 DOI: 10.1128/Mcb.20.6.2075-2086.2000 |
0.544 |
|
| 2000 |
Strom DK, John N, Westendorf JJ, Linggi B, Lutterbach B, Downing JR, Lenny N, Hiebert SW. Expression of the AML-1 oncogene shortens the G1 phase of the cell cycle Journal of Biological Chemistry. 275: 3438-3445. PMID 10652337 DOI: 10.1074/Jbc.275.5.3438 |
0.45 |
|
| 2000 |
Lutterbach B, Westendorf JJ, Linggi B, Isaac S, Seto E, Hiebert SW. A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia Journal of Biological Chemistry. 275: 651-656. PMID 10617663 DOI: 10.1074/Jbc.275.1.651 |
0.786 |
|
| 2000 |
McNeil S, Zeng C, Harrington KS, Hiebert S, Lian JB, Stein JL, van Wijnen AJ, Stein GS. The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 96: 14882-7. PMID 10611307 DOI: 10.1073/Pnas.96.26.14882 |
0.472 |
|
| 2000 |
Melnick AM, Carlile G, Hiebert SW, Licht JD. The eto protein is a corepressor for several wild-type and oncogenic hematopoietic transcription factors Blood. 96. |
0.453 |
|
| 1999 |
Westendorf JJ, Hiebert SW. Mammalian runt-domain proteins and their roles in hematopoiesis, osteogenesis, and leukemia Journal of Cellular Biochemistry. 76: 51-58. PMID 10629103 DOI: 10.1002/(Sici)1097-4644(1999)75:32+<51::Aid-Jcb7>3.0.Co;2-S |
0.5 |
|
| 1999 |
Tang L, Guo B, Javed A, Choi JY, Hiebert S, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Zhou GW. Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2. The Journal of Biological Chemistry. 274: 33580-6. PMID 10559245 DOI: 10.1074/Jbc.274.47.33580 |
0.448 |
|
| 1999 |
Lutterbach B, Hou Y, Durst KL, Hiebert SW. The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor. Proceedings of the National Academy of Sciences of the United States of America. 96: 12822-7. PMID 10536006 DOI: 10.1073/Pnas.96.22.12822 |
0.813 |
|
| 1999 |
Fenrick R, Amann JM, Lutterbach B, Wang L, Westendorf JJ, Downing JR, Hiebert SW. Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein Molecular and Cellular Biology. 19: 6566-6574. PMID 10490596 DOI: 10.1128/Mcb.19.10.6566 |
0.465 |
|
| 1999 |
Westendorf JJ, Mernaugh R, Hiebert SW. Identification and characterization of a protein containing formin homology (FH1/FH2) domains Gene. 232: 173-182. PMID 10352228 DOI: 10.1016/S0378-1119(99)00127-4 |
0.39 |
|
| 1998 |
Fenrick R, Hiebert SW. Role of histone deacetylases in acute leukemia. Journal of Cellular Biochemistry. 72: 194-202. PMID 29345812 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<194::Aid-Jcb24>3.0.Co;2-H |
0.525 |
|
| 1998 |
Fenrick R, Hiebert SW. Role of histone deacetylases in acute leukemia Journal of Cellular Biochemistry. Supplement. 30: 194-202. PMID 9893271 |
0.422 |
|
| 1998 |
Lutterbach B, Westendorf JJ, Linggi B, Patten A, Moniwa M, Davie JR, Huynh KD, Bardwell VJ, Lavinsky RM, Rosenfeld MG, Glass C, Seto E, Hiebert SW. ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Molecular and Cellular Biology. 18: 7176-84. PMID 9819404 DOI: 10.1128/Mcb.18.12.7176 |
0.79 |
|
| 1998 |
Petrovick MS, Hiebert SW, Friedman AD, Hetherington CJ, Tenen DG, Zhang DE. Multiple functional domains of AML1: PU.1 and C/EBPα synergize with different regions of AML1 Molecular and Cellular Biology. 18: 3915-3925. PMID 9632776 DOI: 10.1128/Mcb.18.7.3915 |
0.407 |
|
| 1998 |
Lutterbach B, Sun D, Schuetz J, Hiebert SW. The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein Molecular and Cellular Biology. 18: 3604-3611. PMID 9584201 DOI: 10.1128/Mcb.18.6.3604 |
0.509 |
|
| 1998 |
Ji C, Casinghino S, Chang DJ, Chen Y, Javed A, Ito Y, Hiebert SW, Lian JB, Stein GS, McCarthy TL, Centrella M. CBFa(AML/PEBP2)-related elements in the TGF-β type I receptor promoter and expression with osteoblast differentiation Journal of Cellular Biochemistry. 69: 353-363. PMID 9581873 DOI: 10.1002/(Sici)1097-4644(19980601)69:3<353::Aid-Jcb12>3.0.Co;2-D |
0.38 |
|
| 1998 |
Zeng C, McNeil S, Pockwinse S, Nickerson J, Shopland L, Lawrence JB, Penman S, Hiebert S, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains. Proceedings of the National Academy of Sciences of the United States of America. 95: 1585-9. PMID 9465059 DOI: 10.1073/Pnas.95.4.1585 |
0.428 |
|
| 1998 |
Legare RD, Lu D, Gallagher M, Ho C, Tan X, Barker G, Shimizu K, Ohki M, Lenny N, Hiebert S, Gilliland DG. CBFA2, frequently rearranged in leukemia, is not responsible for a familial leukemia syndrome. Leukemia. 11: 2111-9. PMID 9447828 DOI: 10.1038/Sj.Leu.2400852 |
0.342 |
|
| 1998 |
Westendorf JJ, Yamamoto CM, Lenny N, Downing JR, Selsted ME, Hiebert SW. The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-α, inhibits C/EBP-α-dependent transcription, and blocks granulocytic differentiation Molecular and Cellular Biology. 18: 322-333. PMID 9418879 DOI: 10.1128/Mcb.18.1.322 |
0.412 |
|
| 1997 |
Lenny N, Westendorf JJ, Hiebert SW. Transcriptional regulation during myelopoiesis Molecular Biology Reports. 24: 157-168. PMID 9291089 DOI: 10.1023/A:1006859700409 |
0.489 |
|
| 1997 |
Lindenmuth DM, van Wijnen AJ, Hiebert S, Stein JL, Lian JB, Stein GS. Subcellular partitioning of transcription factors during osteoblast differentiation: developmental association of the AML/CBF alpha/PEBP2 alpha-related transcription factor-NMP-2 with the nuclear matrix. Journal of Cellular Biochemistry. 66: 123-32. PMID 9215534 DOI: 10.1002/(Sici)1097-4644(19970701)66:1<123::Aid-Jcb13>3.0.Co;2-K |
0.441 |
|
| 1997 |
Banerjee C, McCabe LR, Choi JY, Hiebert SW, Stein JL, Stein GS, Lian JB. Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex Journal of Cellular Biochemistry. 66: 1-8. PMID 9215522 DOI: 10.1002/(Sici)1097-4644(19970701)66:1<1::Aid-Jcb1>3.0.Co;2-V |
0.473 |
|
| 1997 |
Zeng C, van Wijnen AJ, Stein JL, Meyers S, Sun W, Shopland L, Lawrence JB, Penman S, Lian JB, Stein GS, Hiebert SW. Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 94: 6746-51. PMID 9192636 DOI: 10.1073/Pnas.94.13.6746 |
0.467 |
|
| 1997 |
Nip J, Strom DK, Fee BE, Zambetti G, Cleveland JL, Hiebert SW. E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis Molecular and Cellular Biology. 17: 1049-1056. PMID 9032231 DOI: 10.1128/Mcb.17.3.1049 |
0.363 |
|
| 1996 |
Rhoades KL, Hetherington CJ, Rowley JD, Hiebert SW, Nucifora G, Tenen DG, Zhang DE. Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis Proceedings of the National Academy of Sciences of the United States of America. 93: 11895-11900. PMID 8876234 DOI: 10.1073/Pnas.93.21.11895 |
0.377 |
|
| 1996 |
Meyers S, Lenny N, Sun W, Hiebert SW. AML-2 is a potential target for transcriptional regulation by the t(8;21) and t(12;21) fusion proteins in acute leukemia Oncogene. 13: 303-312. PMID 8710369 |
0.44 |
|
| 1996 |
Hiebert SW, Sun W, Davis JN, Golub T, Shurtleff S, Buijs A, Downing JR, Grosveld G, Roussell MF, Gilliland DG, Lenny N, Meyers S. The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription. Molecular and Cellular Biology. 16: 1349-55. PMID 8657108 DOI: 10.1128/Mcb.16.4.1349 |
0.465 |
|
| 1996 |
Banerjee C, Hiebert SW, Stein JL, Lian JB, Stein GS. An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin gene Proceedings of the National Academy of Sciences of the United States of America. 93: 4968-4973. PMID 8643513 DOI: 10.1073/Pnas.93.10.4968 |
0.506 |
|
| 1996 |
Zhang DE, Hetherington CJ, Meyers S, Rhoades KL, Larson CJ, Chen - HM, Hiebert SW, Tenen DG. CCAAT enhancer-binding protein (C/EBP) and AML1 (CBFα2) synergistically activate the macrophage colony-stimulating factor receptor promoter Molecular and Cellular Biology. 16: 1231-1240. PMID 8622667 DOI: 10.1128/Mcb.16.3.1231 |
0.459 |
|
| 1996 |
Hitomi M, Shu J, Strom D, Hiebert SW, Harter ML, Stacey DW. Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation Journal of Biological Chemistry. 271: 9376-9383. PMID 8621603 DOI: 10.1074/Jbc.271.16.9376 |
0.322 |
|
| 1996 |
Hiebert SW, Downing JR, Lenny N, Meyers S. Transcriptional regulation by the t(8;21) fusion protein, AML-1/ETO Current Topics in Microbiology and Immunology. 211: 253-258. PMID 8585956 DOI: 10.1007/978-3-642-85232-9_25 |
0.385 |
|
| 1996 |
Zent C, Kim N, Hiebert S, Zhang DE, Tenen DG, Rowley JD, Nucifora G. Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties. Current Topics in Microbiology and Immunology. 211: 243-52. PMID 8585955 DOI: 10.1007/978-3-642-85232-9_24 |
0.522 |
|
| 1996 |
Okuda T, Van Deursen J, Hiebert SW, Grosveld G, Downing JR. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis Cell. 84: 321-330. PMID 8565077 DOI: 10.1016/S0092-8674(00)80986-1 |
0.418 |
|
| 1995 |
Meyers S, Hiebert SW. Indirect and direct disruption of transcriptional regulation in cancer: E2F and AML-1 Critical Reviews in Eukaryotic Gene Expression. 5: 365-383. PMID 8834231 DOI: 10.1615/Critreveukargeneexpr.V5.I3-4.70 |
0.515 |
|
| 1995 |
Frank R, Zhang J, Uchida H, Meyers S, Hiebert SW, Nimer SD. The AML1/ETO fusion protein blocks transactivation of the GM-CSF promoter by AML1B Oncogene. 11: 2666-2674. PMID 8545124 |
0.357 |
|
| 1995 |
Hiebert SW, Packham G, Strom DK, Haffner R, Oren M, Zambetti G, Cleveland JL. E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis Molecular and Cellular Biology. 15: 6864-6874. PMID 8524253 DOI: 10.1128/Mcb.15.12.6864 |
0.364 |
|
| 1995 |
Meyers S, Lenny N, Hiebert SW. The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation Molecular and Cellular Biology. 15: 1974-1982. PMID 7891692 DOI: 10.1128/Mcb.15.4.1974 |
0.505 |
|
| 1995 |
Shurtleff SA, Meyers S, Hiebert SW, Raimondi SC, Head DR, Willman CL, Wolman S, Slovak ML, Carroll AJ, Behm F, Hulshof MG, Motroni TA, Okuda T, Liu P, Collins FS, et al. Heterogeneity in CBFβ/MYH11 fusion messages encoded by the inv(16)(p13q22) and the t(16;16)(p13;q22) in acute myelogenous leukemia Blood. 85: 3695-3703. PMID 7780153 |
0.32 |
|
| 1995 |
Golub TR, Barker GF, Bohlander SK, Hiebert SW, Ward DC, Bray-Ward P, Morgan E, Raimondi SC, Rowley JD, Gilliland DG. Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 92: 4917-21. PMID 7761424 DOI: 10.1073/Pnas.92.11.4917 |
0.479 |
|
| 1995 |
Merriman HL, Van Wijnen AJ, Hiebert S, Bidwell JP, Fey E, Lian J, Stein J, Stein GS. The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: Interactions with the osteocalcin gene promoter Biochemistry. 34: 13125-13132. PMID 7548073 DOI: 10.1021/Bi00040A025 |
0.485 |
|
| 1995 |
Lenny N, Meyers S, Hiebert SW. Functional domains of the t(8;21) fusion protein, AML-1/ETO Oncogene. 11: 1760-1769. PMID 7478604 |
0.311 |
|
| 1995 |
Shurtleff S, Meyers S, Hiebert S, Raimondi S, Willman C, Wolman S, Slovak M, Carroll A, Behm F. Heterogeneity in CBF beta/MYH11 fusion messages encoded by the inv(16)(p13q22) and the t(16;16)(p13;q22) in acute myelogenous leukemia. Blood. 85: 3695-3703. DOI: 10.1182/Blood.V85.12.3695.Bloodjournal85123695 |
0.359 |
|
| 1994 |
Dobrowolski SF, Stacey DW, Harter ML, Stine JT, Hiebert SW. An E2F dominant negative mutant blocks E1A induced cell cycle progression Oncogene. 9: 2605-2612. PMID 8058324 |
0.364 |
|
| 1994 |
Nuchprayoon I, Meyers S, Scott LM, Suzow J, Hiebert S, Friedman AD. PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells. Molecular and Cellular Biology. 14: 5558-68. PMID 8035830 DOI: 10.1128/Mcb.14.8.5558 |
0.377 |
|
| 1993 |
Hiebert SW. Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter reppression and pRb-mediated growth suppression Molecular and Cellular Biology. 13: 3384-3391. PMID 8497257 DOI: 10.1128/Mcb.13.6.3384 |
0.414 |
|
| 1993 |
Kato J, Matsushime H, Hiebert SW, Ewen ME, Sherr CJ. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4 Genes and Development. 7: 331-342. PMID 8449399 DOI: 10.1101/Gad.7.3.331 |
0.316 |
|
| 1993 |
Meyers S, Downing JR, Hiebert SW. Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: The runt homology domain is required for DNA binding and protein-protein interactions Molecular and Cellular Biology. 13: 6336-6345. PMID 8413232 DOI: 10.1128/Mcb.13.10.6336 |
0.447 |
|
| 1992 |
Hiebert SW, Chellappan SP, Horowitz JM, Nevins JR. The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F Genes and Development. 6: 177-185. PMID 1531329 DOI: 10.1101/Gad.6.2.177 |
0.456 |
|
| 1991 |
Nevins JR, Chellappan SP, Mudryj M, Hiebert S, Devoto S, Horowitz J, Hunter T, Pines J. E2F transcription factor is a target for the RB protein and the cyclin A protein Cold Spring Harbor Symposia On Quantitative Biology. 56: 157-162. PMID 1840249 DOI: 10.1101/Sqb.1991.056.01.020 |
0.394 |
|
| 1991 |
Mudryj M, Devoto SH, Hiebert SW, Hunter T, Pines J, Nevins JR. Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A Cell. 65: 1243-1253. PMID 1829647 DOI: 10.1016/0092-8674(91)90019-U |
0.363 |
|
| 1991 |
Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins JR. The E2F transcription factor is a cellular target for the RB protein Cell. 65: 1053-1061. PMID 1828392 DOI: 10.1016/0092-8674(91)90557-F |
0.444 |
|
| 1991 |
Hiebert SW, Blake M, Azizkhan J, Nevins JR. Role of E2F transcription factor in E1A-mediated trans activation of cellular genes Journal of Virology. 65: 3547-3552. PMID 1828272 DOI: 10.1128/Jvi.65.7.3547-3552.1991 |
0.395 |
|
| 1990 |
Ng DT, Hiebert SW, Lamb RA. Different roles of individual N-linked oligosaccharide chains in folding, assembly, and transport of the simian virus 5 hemagglutinin-neuraminidase. Molecular and Cellular Biology. 10: 1989-2001. PMID 2183015 DOI: 10.1128/Mcb.10.5.1989 |
0.729 |
|
| 1990 |
Mudryj M, Hiebert SW, Nevins JR. A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway Embo Journal. 9: 2179-2184. PMID 2141565 DOI: 10.1002/J.1460-2075.1990.Tb07387.X |
0.469 |
|
| 1989 |
Hiebert SW, Lipp M, Nevins JR. E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor Proceedings of the National Academy of Sciences of the United States of America. 86: 3594-3598. PMID 2524830 DOI: 10.1073/Pnas.86.10.3594 |
0.418 |
|
| 1988 |
Hiebert SW, Lamb RA. Cell surface expression of glycosylated, nonglycosylated, and truncated forms of a cytoplasmic protein pyruvate kinase. The Journal of Cell Biology. 107: 865-76. PMID 3047152 DOI: 10.1083/Jcb.107.3.865 |
0.553 |
|
| 1988 |
Hiebert SW, Richardson CD, Lamb RA. Cell surface expression and orientation in membranes of the 44-amino-acid SH protein of simian virus 5. Journal of Virology. 62: 2347-57. PMID 2836617 DOI: 10.1128/Jvi.62.7.2347-2357.1988 |
0.533 |
|
| 1988 |
Lamb RA, Hiebert SW, Hull J, Ng D, Williams MA, Zebedee SL. Structure, modification, intracellular transport and function of influenza and paramyxovirus integral membrane proteins Virus Research. 11: 10. DOI: 10.1016/0168-1702(88)90116-5 |
0.709 |
|
| 1986 |
Hiebert SW, Williams MA, Lamb RA. Nucleotide sequence of RNA segment 7 of influenza B/Singapore/222/79: maintenance of a second large open reading frame. Virology. 155: 747-51. PMID 3788064 DOI: 10.1016/0042-6822(86)90237-0 |
0.477 |
|
| 1985 |
Hiebert SW, Paterson RG, Lamb RA. Identification and predicted sequence of a previously unrecognized small hydrophobic protein, SH, of the paramyxovirus simian virus 5. Journal of Virology. 55: 744-51. PMID 4020965 DOI: 10.1128/Jvi.55.3.744-751.1985 |
0.536 |
|
| 1985 |
Hiebert SW, Paterson RG, Lamb RA. Hemagglutinin-neuraminidase protein of the paramyxovirus simian virus 5: nucleotide sequence of the mRNA predicts an N-terminal membrane anchor. Journal of Virology. 54: 1-6. PMID 3973974 DOI: 10.1128/Jvi.54.1.1-6.1985 |
0.499 |
|
| 1985 |
Paterson RG, Hiebert SW, Lamb RA. Expression at the cell surface of biologically active fusion and hemagglutinin/neuraminidase proteins of the paramyxovirus simian virus 5 from cloned cDNA. Proceedings of the National Academy of Sciences of the United States of America. 82: 7520-4. PMID 3865176 DOI: 10.1073/Pnas.82.22.7520 |
0.533 |
|
| 1985 |
Paterson RG, Hiebert SW, Lamb RA. Expression of biologically active F and HN proteins of the paramyxovirus SV5 from cloned cDNA Virus Research. 3: 6. DOI: 10.1016/0168-1702(85)90265-5 |
0.503 |
|
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