Mark J. Koenigsknecht, Ph.D. - Publications

Affiliations: 
2011 University of Wisconsin, Madison, Madison, WI 
Area:
Microbiology Biology, Genetics, Biochemistry

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yu A, Koenigsknecht MJ, Hens B, Baker JR, Wen B, Jackson TL, Pai MP, Hasler W, Amidon GL, Sun D. Mechanistic Deconvolution of Oral Absorption Model with Dynamic Gastrointestinal Fluid to Predict Regional Rate and Extent of GI Drug Dissolution. The Aaps Journal. 22: 3. PMID 31712917 DOI: 10.1208/S12248-019-0385-Z  0.317
2018 Paixão P, Bermejo M, Hens B, Tsume Y, Dickens J, Shedden K, Salehi N, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Wysocki J, Wen B, Lee A, et al. Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State. Molecular Pharmaceutics. PMID 30417648 DOI: 10.1021/Acs.Molpharmaceut.8B00736  0.347
2018 Bermejo M, Paixão P, Hens B, Tsume Y, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Dickens J, Shedden KA, Wen B, Wysocki J, Löbenberg R, Lee A, et al. Linking the Gastrointestinal Behavior of Ibuprofen with The Systemic Exposure Between and Within Humans - Part 1: Fasted State. Molecular Pharmaceutics. PMID 30372084 DOI: 10.1021/Acs.Molpharmaceut.8B00515  0.337
2018 Paixão P, Bermejo M, Hens B, Tsume Y, Dickens J, Shedden K, Salehi N, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Wysocki J, Wen B, Lee A, et al. Gastric Emptying and Intestinal Appearance of Nonabsorbable Drugs Phenol Red and Paromomycin in Human Subjects: A Multi-Compartment Stomach Approach. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29857136 DOI: 10.1016/J.Ejpb.2018.05.033  0.314
2017 Sun D, Baker JR, Wen B, Frances A, Zhang H, Yu A, Zhao T, Tsume Y, Pai M, Bleske B, Zhang X, Lionberger R, Lee A, Amidon G, Hasler WL, ... Koenigsknecht M, et al. In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract Under Fed and Fasted Conditions. Molecular Pharmaceutics. PMID 28937221 DOI: 10.1021/Acs.Molpharmaceut.7B00425  0.323
2017 Hens B, Tsume Y, Bermejo M, Paixao P, Koenigsknecht M, Baker JR, Hasler WL, Lionberger R, Fan J, Dickens J, Shedden KA, Wen B, Wysocki J, Löbenberg R, Lee A, et al. Low Buffer Capacity and Alternating Motility Along The Human Gastrointestinal Tract: Implications for In Vivo Dissolution and Absorption of Ionizable Drugs. Molecular Pharmaceutics. PMID 28737409 DOI: 10.1021/Acs.Molpharmaceut.7B00426  0.338
2017 Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP. NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nature Immunology. PMID 28288099 DOI: 10.1038/Ni.3690  0.312
2017 Dahl JU, Gray MJ, Bazopoulou D, Beaufay F, Lempart J, Koenigsknecht MJ, Wang Y, Baker JR, Hasler WL, Young VB, Sun D, Jakob U. The anti-inflammatory drug mesalamine targets bacterial polyphosphate accumulation. Nature Microbiology. 2: 16267. PMID 28112760 DOI: 10.1038/Nmicrobiol.2016.267  0.332
2017 Koenigsknecht M, Baker J, Fioritto AF, Tsume Y, Wen B, Dickens J, Yu A, Wysocki J, Shedden K, Bleske B, Lee A, Hasler WL, Amidon G, Sun D. Gastrointestinal Motility and Luminal pH Influence in Vivo Dissolution and Systemic Absorption of Drug Product in Human Gastrointestinal Tract Under Fed and Fasted Conditions Gastroenterology. 152: S206. DOI: 10.1016/S0016-5085(17)30994-0  0.326
2016 Yu A, Baker JR, Fioritto AF, Wang Y, Luo R, Li S, Wen B, Bly M, Tsume Y, Koenigsknecht MJ, Zhang X, Lionberger R, Amidon GL, Hasler WL, Sun D. Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract. Molecular Pharmaceutics. PMID 28009518 DOI: 10.1021/Acs.Molpharmaceut.6B00641  0.317
2016 Mathewson ND, Jenq R, Mathew AV, Koenigsknecht M, Hanash A, Toubai T, Oravecz-Wilson K, Wu SR, Sun Y, Rossi C, Fujiwara H, Byun J, Shono Y, Lindemans C, Calafiore M, et al. Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease. Nature Immunology. PMID 26998764 DOI: 10.1038/Ni.3400  0.334
2016 Fioritto AF, Yu A, Baker J, Collins K, Wen B, Wang Y, Luo R, Li S, Bleske B, Johnson M, Koenigsknecht M, Hasler WL, Sun D. Mo1318 Direct Comparison of In Vivo Drug Release Profiles of Three Locally-Acting Drug Products of Mesalamine in the Gastrointestinal Tract and Correlation With Systemic Exposure and Fecal Concentrations in Healthy Humans Gastroenterology. 150: S696. DOI: 10.1016/S0016-5085(16)32375-7  0.308
2015 Koenigsknecht MJ, Theriot CM, Bergin IL, Schumacher CA, Schloss PD, Young VB. Dynamics and establishment of Clostridium difficile infection in the murine gastrointestinal tract. Infection and Immunity. 83: 934-41. PMID 25534943 DOI: 10.1128/Iai.02768-14  0.323
2015 Fioritto AF, Baker J, Collins K, Wen B, Wang Y, Luo R, Bleske B, Johnson M, Koenigsknecht M, Hasler WL, Sun D. Mo1224 Contrasting Regional Availability of Different Mesalamine Products in the Gastrointestinal Tract in Healthy Humans Using a Novel Multi-Port Luminal Aspiration System and Correlation With Systemic Absorption Gastroenterology. 148: S-642-S-643. DOI: 10.1016/S0016-5085(15)32169-7  0.3
2014 Theriot CM, Koenigsknecht MJ, Carlson PE, Hatton GE, Nelson AM, Li B, Huffnagle GB, Z Li J, Young VB. Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection. Nature Communications. 5: 3114. PMID 24445449 DOI: 10.1038/Ncomms4114  0.372
2012 Koenigsknecht MJ, Lambrecht JA, Fenlon LA, Downs DM. Perturbations in histidine biosynthesis uncover robustness in the metabolic network of Salmonella enterica. Plos One. 7: e48207. PMID 23133571 DOI: 10.1371/Journal.Pone.0048207  0.551
2012 Reeves AE, Koenigsknecht MJ, Bergin IL, Young VB. Suppression of Clostridium difficile in the gastrointestinal tracts of germfree mice inoculated with a murine isolate from the family Lachnospiraceae. Infection and Immunity. 80: 3786-94. PMID 22890996 DOI: 10.1128/Iai.00647-12  0.306
2010 Koenigsknecht MJ, Downs DM. Thiamine biosynthesis can be used to dissect metabolic integration. Trends in Microbiology. 18: 240-7. PMID 20382023 DOI: 10.1016/J.Tim.2010.03.003  0.532
2010 Koenigsknecht MJ, Fenlon LA, Downs DM. Phosphoribosylpyrophosphate synthetase (PrsA) variants alter cellular pools of ribose 5-phosphate and influence thiamine synthesis in Salmonella enterica. Microbiology (Reading, England). 156: 950-9. PMID 19959576 DOI: 10.1099/Mic.0.033050-0  0.557
2007 Koenigsknecht MJ, Ramos I, Downs DM. Glutamine phosphoribosylpyrophosphate amidotransferase-independent phosphoribosyl amine synthesis from ribose 5-phosphate and glutamine or asparagine. The Journal of Biological Chemistry. 282: 28379-84. PMID 17686772 DOI: 10.1074/Jbc.M704024200  0.538
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