Christine A. Biron - Publications

Affiliations: 
Brown University, Providence, RI 
Area:
Immunology, Microbiology Biology

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Biron CA. Innate Immunity: Recognizing and Responding to Foreign Invaders-No Training Needed Viral Pathogenesis: From Basics to Systems Biology: Third Edition. 41-55. DOI: 10.1016/B978-0-12-800964-2.00004-5  0.92
2015 Biron CA, Tarrio ML. Immunoregulatory cytokine networks: 60 years of learning from murine cytomegalovirus. Medical Microbiology and Immunology. 204: 345-54. PMID 25850988 DOI: 10.1007/s00430-015-0412-3  0.92
2014 Suarez-Ramirez JE, Tarrio ML, Kim K, Demers DA, Biron CA. CD8 T cells in innate immune responses: using STAT4-dependent but antigen-independent pathways to gamma interferon during viral infection. Mbio. 5: e01978-14. PMID 25336459 DOI: 10.1128/mBio.01978-14  0.92
2014 Donnelly RP, Loftus RM, Keating SE, Liou KT, Biron CA, Gardiner CM, Finlay DK. mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function. Journal of Immunology (Baltimore, Md. : 1950). 193: 4477-84. PMID 25261477 DOI: 10.4049/jimmunol.1401558  0.92
2014 Wynne C, Lazzari E, Smith S, McCarthy EM, Ní Gabhann J, Kallal LE, Higgs R, Greco A, Cryan SA, Biron CA, Jefferies CA. TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems. Plos One. 9: e101503. PMID 24999993 DOI: 10.1371/journal.pone.0101503  0.92
2014 Tarrio ML, Lee SH, Fragoso MF, Sun HW, Kanno Y, O'Shea JJ, Biron CA. Proliferation conditions promote intrinsic changes in NK cells for an IL-10 response. Journal of Immunology (Baltimore, Md. : 1950). 193: 354-63. PMID 24907347 DOI: 10.4049/jimmunol.1302999  0.92
2013 Mace EM, Hsu AP, Monaco-Shawver L, Makedonas G, Rosen JB, Dropulic L, Cohen JI, Frenkel EP, Bagwell JC, Sullivan JL, Biron CA, Spalding C, Zerbe CS, Uzel G, Holland SM, et al. Mutations in GATA2 cause human NK cell deficiency with specific loss of the CD56(bright) subset. Blood. 121: 2669-77. PMID 23365458 DOI: 10.1182/blood-2012-09-453969  0.92
2012 Gil MP, Ploquin MJ, Watford WT, Lee SH, Kim K, Wang X, Kanno Y, O'Shea JJ, Biron CA. Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function. Blood. 120: 3718-28. PMID 22968462 DOI: 10.1182/blood-2012-05-428672  0.92
2012 Lee SH, Fragoso MF, Biron CA. Cutting edge: a novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 2712-6. PMID 22888135 DOI: 10.4049/jimmunol.1201528  0.92
2012 Biron CA. Yet another role for natural killer cells: cytotoxicity in immune regulation and viral persistence. Proceedings of the National Academy of Sciences of the United States of America. 109: 1814-5. PMID 22308452 DOI: 10.1073/pnas.1120528109  0.92
2011 Biron CA, Rice CM. Innate immunity: trolling, responding and protecting against viral infections. Current Opinion in Virology. 1: 443-6. PMID 22440907 DOI: 10.1016/j.coviro.2011.11.006  0.92
2011 Vidal SM, Khakoo SI, Biron CA. Natural killer cell responses during viral infections: flexibility and conditioning of innate immunity by experience. Current Opinion in Virology. 1: 497-512. PMID 22180766 DOI: 10.1016/j.coviro.2011.10.017  0.92
2011 Mack EA, Kallal LE, Demers DA, Biron CA. Type 1 interferon induction of natural killer cell gamma interferon production for defense during lymphocytic choriomeningitis virus infection. Mbio. 2. PMID 21828218 DOI: 10.1128/mBio.00169-11  0.92
2010 Biron CA, Casadevall A. On immunologists and microbiologists: ground zero in the battle for interdisciplinary knowledge. Mbio. 1. PMID 21103040 DOI: 10.1128/mBio.00260-10  0.92
2010 Biron CA. More things in heaven and earth: defining innate and adaptive immunity. Nature Immunology. 11: 1080-2. PMID 21079631 DOI: 10.1038/ni1210-1080  0.92
2010 Biron CA. Expansion, maintenance, and memory in NK and T cells during viral infections: responding to pressures for defense and regulation. Plos Pathogens. 6: e1000816. PMID 20361055 DOI: 10.1371/journal.ppat.1000816  0.92
2010 Lee SH, Biron CA. Here today--not gone tomorrow: roles for activating receptors in sustaining NK cells during viral infections. European Journal of Immunology. 40: 923-32. PMID 20209503 DOI: 10.1002/eji.201040304  0.92
2010 Miyagi T, Lee SH, Biron CA. Intracellular staining for analysis of the expression and phosphorylation of signal transducers and activators of transcription (STATs) in NK cells. Methods in Molecular Biology (Clifton, N.J.). 612: 159-75. PMID 20033640 DOI: 10.1007/978-1-60761-362-6_11  0.92
2009 Lee SH, Kim KS, Fodil-Cornu N, Vidal SM, Biron CA. Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection. The Journal of Experimental Medicine. 206: 2235-51. PMID 19720840 DOI: 10.1084/jem.20082387  0.92
2008 Fodil-Cornu N, Lee SH, Belanger S, Makrigiannis AP, Biron CA, Buller RM, Vidal SM. Ly49h-deficient C57BL/6 mice: a new mouse cytomegalovirus-susceptible model remains resistant to unrelated pathogens controlled by the NK gene complex. Journal of Immunology (Baltimore, Md. : 1950). 181: 6394-405. PMID 18941230  0.92
2007 Miyagi T, Gil MP, Wang X, Louten J, Chu WM, Biron CA. High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells. The Journal of Experimental Medicine. 204: 2383-96. PMID 17846149 DOI: 10.1084/jem.20070401  0.92
2007 Contractor N, Louten J, Kim L, Biron CA, Kelsall BL. Cutting edge: Peyer's patch plasmacytoid dendritic cells (pDCs) produce low levels of type I interferons: possible role for IL-10, TGFbeta, and prostaglandin E2 in conditioning a unique mucosal pDC phenotype. Journal of Immunology (Baltimore, Md. : 1950). 179: 2690-4. PMID 17709480  0.92
2007 Ivanov S, Dragoi AM, Wang X, Dallacosta C, Louten J, Musco G, Sitia G, Yap GS, Wan Y, Biron CA, Bianchi ME, Wang H, Chu WM. A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood. 110: 1970-81. PMID 17548579 DOI: 10.1182/blood-2006-09-044776  0.92
2007 Lee SH, Miyagi T, Biron CA. Keeping NK cells in highly regulated antiviral warfare. Trends in Immunology. 28: 252-9. PMID 17466596 DOI: 10.1016/j.it.2007.04.001  0.92
2007 Ryman KD, Gardner CL, Meier KC, Biron CA, Johnston RE, Klimstra WB. Early restriction of alphavirus replication and dissemination contributes to age-dependent attenuation of systemic hyperinflammatory disease. The Journal of General Virology. 88: 518-29. PMID 17251570 DOI: 10.1099/vir.0.82359-0  0.92
2006 Louten J, van Rooijen N, Biron CA. Type 1 IFN deficiency in the absence of normal splenic architecture during lymphocytic choriomeningitis virus infection. Journal of Immunology (Baltimore, Md. : 1950). 177: 3266-72. PMID 16920967  0.92
2006 Sjölin H, Robbins SH, Bessou G, Hidmark A, Tomasello E, Johansson M, Hall H, Charifi F, Karlsson Hedestam GB, Biron CA, Kärre K, Höglund P, Vivier E, Dalod M. DAP12 signaling regulates plasmacytoid dendritic cell homeostasis and down-modulates their function during viral infection. Journal of Immunology (Baltimore, Md. : 1950). 177: 2908-16. PMID 16920926  0.92
2006 Allman D, Dalod M, Asselin-Paturel C, Delale T, Robbins SH, Trinchieri G, Biron CA, Kastner P, Chan S. Ikaros is required for plasmacytoid dendritic cell differentiation. Blood. 108: 4025-34. PMID 16912230 DOI: 10.1182/blood-2006-03-007757  0.92
2006 García-Sastre A, Biron CA. Type 1 interferons and the virus-host relationship: a lesson in détente . Science (New York, N.Y.). 312: 879-82. PMID 16690858 DOI: 10.1126/science.1125676  0.92
2006 Huang D, Shi FD, Jung S, Pien GC, Wang J, Salazar-Mather TP, He TT, Weaver JT, Ljunggren HG, Biron CA, Littman DR, Ransohoff RM. The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 896-905. PMID 16675847 DOI: 10.1096/fj.05-5465com  0.92
2006 Gil MP, Salomon R, Louten J, Biron CA. Modulation of STAT1 protein levels: a mechanism shaping CD8 T-cell responses in vivo. Blood. 107: 987-93. PMID 16210337 DOI: 10.1182/blood-2005-07-2834  0.92
2005 Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE, Kastner P, Chan S, Akira S, Vicari A, Biron CA, Trinchieri G, Brière F. MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo. Journal of Immunology (Baltimore, Md. : 1950). 175: 6723-32. PMID 16272328  0.92
2005 Silverman MN, Pearce BD, Biron CA, Miller AH. Immune modulation of the hypothalamic-pituitary-adrenal (HPA) axis during viral infection. Viral Immunology. 18: 41-78. PMID 15802953 DOI: 10.1089/vim.2005.18.41  0.92
2005 Morra M, Barrington RA, Abadia-Molina AC, Okamoto S, Julien A, Gullo C, Kalsy A, Edwards MJ, Chen G, Spolski R, Leonard WJ, Huber BT, Borrow P, Biron CA, Satoskar AR, et al. Defective B cell responses in the absence of SH2D1A. Proceedings of the National Academy of Sciences of the United States of America. 102: 4819-23. PMID 15774582 DOI: 10.1073/pnas.0408681102  0.92
2005 Hokeness KL, Kuziel WA, Biron CA, Salazar-Mather TP. Monocyte chemoattractant protein-1 and CCR2 interactions are required for IFN-alpha/beta-induced inflammatory responses and antiviral defense in liver. Journal of Immunology (Baltimore, Md. : 1950). 174: 1549-56. PMID 15661915  0.92
2004 Townsend MJ, Weinmann AS, Matsuda JL, Salomon R, Farnham PJ, Biron CA, Gapin L, Glimcher LH. T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity. 20: 477-94. PMID 15084276 DOI: 10.1016/S1074-7613(04)00076-7  0.92
2004 Silverman MN, Miller AH, Biron CA, Pearce BD. Characterization of an interleukin-6- and adrenocorticotropin-dependent, immune-to-adrenal pathway during viral infection. Endocrinology. 145: 3580-9. PMID 15044377 DOI: 10.1210/en.2003-1421  0.92
2003 Serbina NV, Salazar-Mather TP, Biron CA, Kuziel WA, Pamer EG. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity. 19: 59-70. PMID 12871639 DOI: 10.1016/S1074-7613(03)00171-7  0.92
2003 Dalod M, Hamilton T, Salomon R, Salazar-Mather TP, Henry SC, Hamilton JD, Biron CA. Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta. The Journal of Experimental Medicine. 197: 885-98. PMID 12682109 DOI: 10.1084/jem.20021522  0.92
2002 Pien GC, Nguyen KB, Malmgaard L, Satoskar AR, Biron CA. A unique mechanism for innate cytokine promotion of T cell responses to viral infections. Journal of Immunology (Baltimore, Md. : 1950). 169: 5827-37. PMID 12421964  0.92
2002 Nguyen KB, Salazar-Mather TP, Dalod MY, Van Deusen JB, Wei XQ, Liew FY, Caligiuri MA, Durbin JE, Biron CA. Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection. Journal of Immunology (Baltimore, Md. : 1950). 169: 4279-87. PMID 12370359  0.92
2002 Nguyen KB, Watford WT, Salomon R, Hofmann SR, Pien GC, Morinobu A, Gadina M, O'Shea JJ, Biron CA. Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection. Science (New York, N.Y.). 297: 2063-6. PMID 12242445 DOI: 10.1126/science.1074900  0.92
2002 Salazar-Mather TP, Lewis CA, Biron CA. Type I interferons regulate inflammatory cell trafficking and macrophage inflammatory protein 1alpha delivery to the liver. The Journal of Clinical Investigation. 110: 321-30. PMID 12163451 DOI: 10.1172/JCI15376  0.92
2002 Kelsall BL, Biron CA, Sharma O, Kaye PM. Dendritic cells at the host-pathogen interface. Nature Immunology. 3: 699-702. PMID 12145651 DOI: 10.1038/ni0802-699  0.92
2002 Vivier E, Biron CA. Immunology. A pathogen receptor on natural killer cells. Science (New York, N.Y.). 296: 1248-9. PMID 12016296 DOI: 10.1126/science.1072447  0.92
2002 Biron CA, Nguyen KB, Pien GC. Innate immune responses to LCMV infections: natural killer cells and cytokines. Current Topics in Microbiology and Immunology. 263: 7-27. PMID 11987821  0.92
2002 Malmgaard L, Salazar-Mather TP, Lewis CA, Biron CA. Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways. Journal of Virology. 76: 4520-5. PMID 11932417 DOI: 10.1128/JVI.76.9.4520-4525.2002  0.92
2002 Robbins SH, Nguyen KB, Takahashi N, Mikayama T, Biron CA, Brossay L. Cutting edge: inhibitory functions of the killer cell lectin-like receptor G1 molecule during the activation of mouse NK cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 2585-9. PMID 11884419  0.92
2002 Dalod M, Salazar-Mather TP, Malmgaard L, Lewis C, Asselin-Paturel C, Brière F, Trinchieri G, Biron CA. Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo. The Journal of Experimental Medicine. 195: 517-28. PMID 11854364 DOI: 10.1084/jem.20011672  0.92
2001 Su HC, Nguyen KB, Salazar-Mather TP, Ruzek MC, Dalod MY, Biron CA. NK cell functions restrain T cell responses during viral infections. European Journal of Immunology. 31: 3048-55. PMID 11592081 DOI: 10.1002/1521-4141(2001010)31:10<3048::AID-IMMU3048>3.0.CO;2-1  0.92
2001 Biron CA, Brossay L. NK cells and NKT cells in innate defense against viral infections Current Opinion in Immunology. 13: 458-464. PMID 11498302 DOI: 10.1016/S0952-7915(00)00241-7  0.92
2001 Pearce BD, Biron CA, Miller AH. Neuroendocrine-immune interactions during viral infections Advances in Virus Research. 56: 469-513. PMID 11450310  0.92
2001 Biron CA. Interferons α and β as immune regulators - A new look Immunity. 14: 661-664. PMID 11420036 DOI: 10.1016/S1074-7613(01)00154-6  0.92
2001 Wu C, Nguyen KB, Pien GC, Wang N, Gullo C, Howie D, Sosa MR, Edwards MJ, Borrow P, Satoskar AR, Sharpe AH, Biron CA, Terhorst C. SAP controls T cell responses to virus and terminal differentiation of TH2 cells. Nature Immunology. 2: 410-4. PMID 11323694 DOI: 10.1038/87713  0.92
2001 Doughty LA, Nguyen KB, Durbin JE, Biron CA. A role for IFN-αβ in virus infection-induced sensitization to endotoxin Journal of Immunology. 166: 2658-2664. PMID 11160329  0.92
2000 Sayós J, Nguyen KB, Wu C, Stepp SE, Howie D, Schatzle JD, Kumar V, Biron CA, Terhorst C. Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B4. International Immunology. 12: 1749-57. PMID 11099315  0.92
2000 Pien GC, Satoskar AR, Takeda K, Akira S, Biron CA. Cutting edge: selective IL-18 requirements for induction of compartmental IFN-gamma responses during viral infection. Journal of Immunology (Baltimore, Md. : 1950). 165: 4787-91. PMID 11046000  0.92
2000 Nguyen KB, Cousens LP, Doughty LA, Pien GC, Durbin JE, Biron CA. Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox. Nature Immunology. 1: 70-6. PMID 10881178 DOI: 10.1038/76940  0.92
2000 Salazar-Mather TP, Hamilton TA, Biron CA. A chemokine-to-cytokine-to-chemokine cascade critical in antiviral defense Journal of Clinical Investigation. 105: 985-993. PMID 10749577  0.92
2000 Ryman KD, Klimstra WB, Nguyen KB, Biron CA, Johnston RE. Alpha/beta interferon protects adult mice from fatal Sindbis virus infection and is an important determinant of cell and tissue tropism. Journal of Virology. 74: 3366-78. PMID 10708454 DOI: 10.1128/JVI.74.7.3366-3378.2000  0.92
2000 Taylor GA, Collazo CM, Yap GS, Nguyen K, Gregorio TA, Taylor LS, Eagleson B, Secrest L, Southon EA, Reid SW, Tessarollo L, Bray M, McVicar DW, Komschlies KL, Young HA, ... Biron CA, et al. Pathogen-specific loss of host resistance in mice lacking the IFN-γ- inducible gene IGTP Proceedings of the National Academy of Sciences of the United States of America. 97: 751-755. PMID 10639151 DOI: 10.1073/pnas.97.2.751  0.92
2000 Karp CL, Biron CA, Irani DN. Interferon β in multiple sclerosis: Is IL-12 suppression the key? Immunology Today. 21: 24-28. PMID 10637555 DOI: 10.1016/S0167-5699(99)01541-8  0.92
2000 Pien GC, Biron CA. Compartmental differences in NK cell responsiveness to IL-12 during lymphocytic choriomeningitis virus infection. Journal of Immunology (Baltimore, Md. : 1950). 164: 994-1001. PMID 10623849  0.92
1999 Klimstra WB, Ryman KD, Bernard KA, Nguyen KB, Biron CA, Johnston RE. Infection of neonatal mice with sindbis virus results in a systemic inflammatory response syndrome. Journal of Virology. 73: 10387-98. PMID 10559357  0.92
1999 Biron CA. Initial and innate responses to viral infections - Pattern setting in immunity or disease Current Opinion in Microbiology. 2: 374-381. PMID 10458991 DOI: 10.1016/S1369-5274(99)80066-6  0.92
1999 Hanson LK, Slater JS, Karabekian Z, Virgin IV HW, Biron CA, Ruzek MC, Van Rooijen N, Ciavarra RP, Stenberg RM, Campbell AE. Replication of murine cytomegalovirus in differentiated macrophages as a determinant of viral pathogenesis Journal of Virology. 73: 5970-5980. PMID 10364349  0.92
1999 Biron CA, Nguyen KB, Pien GC, Cousens LP, Salazar-Mather TP. Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annual Review of Immunology. 17: 189-220. PMID 10358757 DOI: 10.1146/annurev.immunol.17.1.189  0.92
1999 Jian S, Ruzek MC, Velupillai P, De Aos I, Wang B, Harn DA, Sancho J, Biron CA, Terhorst C. Generation of antigen-specific cytotoxic T lymphocytes and regulation of cytokine production takes place in the absence of CD3ζ International Immunology. 11: 845-858. PMID 10330289 DOI: 10.1093/intimm/11.5.845  0.92
1999 Nguyen KB, Biron CA. Synergism for cytokine-mediated disease during concurrent endotoxin and viral challenges: roles for NK and T cell IFN-gamma production. Journal of Immunology (Baltimore, Md. : 1950). 162: 5238-46. PMID 10227998  0.92
1999 Cousens LP, Peterson R, Hsu S, Dorner A, Altman JD, Ahmed R, Biron CA. Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection. The Journal of Experimental Medicine. 189: 1315-28. PMID 10209048 DOI: 10.1084/jem.189.8.1315  0.92
1999 Ruzek MC, Pearce BD, Miller AH, Biron CA. Endogenous glucocorticoids protect against cytokine-mediated lethality during viral infection Journal of Immunology. 162: 3527-3533. PMID 10092810  0.92
1999 Doughty LA, Nguyen KB, Biron CA. A pathway for virus-induced sensitization to endotoxin challenge Critical Care Medicine. 27.  0.92
1998 Biron CA, Cousens LP, Ruzek MC, Su HC, Salazar-Mather TP. Early cytokine responses to viral infections and their roles in shaping endogenous cellular immunity Advances in Experimental Medicine and Biology. 452: 143-149. PMID 9889967  0.92
1998 Biron CA. Role of early cytokines, including alpha and beta interferons (IFN-α/β), in innate and adaptive immune responses to viral infections Seminars in Immunology. 10: 383-390. PMID 9799713 DOI: 10.1006/smim.1998.0138  0.92
1998 Su HC, Cousens LP, Fast LD, Slifka MK, Bungiro RD, Ahmed R, Biron CA. CD4+ and CD8+ T cell interactions in IFN-γ and IL-4 responses to viral infections: Requirements for IL-2 Journal of Immunology. 160: 5007-5017. PMID 9590250  0.92
1998 Salazar-Mather TP, Orange JS, Biron CA. Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1α (MIP-1α)-dependent pathways Journal of Experimental Medicine. 187: 1-14. PMID 9419206 DOI: 10.1084/jem.187.1.1  0.92
1998 Cousens LP, Biron CA. Roles for innate cytokine pathways in regulating adaptive T cell responses to viral infections Faseb Journal. 12.  0.92
1997 Orange JS, Salazar-Mather TP, Opal SM, Biron CA. Mechanisms for virus-induced liver disease: Tumor necrosis factor- mediated pathology independent of natural killer and T cells during murine cytomegalovirus infection Journal of Virology. 71: 9248-9258. PMID 9371583  0.92
1997 Miller AH, Spencer RL, Pearce BD, Pisell TL, Tanapat P, Leung JJ, Dhabhar FS, McEwen BS, Biron CA. 1996 Curt P. Richter Award. Effects of viral infection on corticosterone secretion and glucocorticoid receptor binding in immune tissues. Psychoneuroendocrinology. 22: 455-74. PMID 9364623 DOI: 10.1016/S0306-4530(97)00028-0  0.92
1997 Biron CA. Natural killer cell regulation during viral infection Biochemical Society Transactions. 25: 687-690. PMID 9191183  0.92
1997 Ruzek MC, Miller AH, Opal SM, Pearce BD, Biron CA. Characterization of early cytokine responses and an interleukin (IL)-6- dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection Journal of Experimental Medicine. 185: 1185-1192. PMID 9104805 DOI: 10.1084/jem.185.7.1185  0.92
1997 McEwen BS, Biron CA, Brunson KW, Bulloch K, Chambers WH, Dhabhar FS, Goldfarb RH, Kitson RP, Miller AH, Spencer RL, Weiss JM. The role of adrenocorticoids as modulators of immune function in health and disease: neural, endocrine and immune interactions. Brain Research. Brain Research Reviews. 23: 79-133. PMID 9063588 DOI: 10.1016/S0165-0173(96)00012-4  0.92
1997 Biron CA. Activation and function of natural killer cell responses during viral infections Current Opinion in Immunology. 9: 24-34. PMID 9039782 DOI: 10.1016/S0952-7915(97)80155-0  0.92
1997 Bonyadi M, Rusholme SAB, Cousins FM, Su HC, Biron CA, Farrall M, Akhurst RJ. Mapping of a major genetic modifier of embryonic lethality in TGFβ1 knockout mice Nature Genetics. 15: 207-211. PMID 9020852 DOI: 10.1038/ng0297-207  0.92
1997 Cousens LP, Orange JS, Su HC, Biron CA. Interferon-α/β inhibition of interleukin 12 and interferon-γ production in vitro and endogenously during viral infection Proceedings of the National Academy of Sciences of the United States of America. 94: 634-639. PMID 9012836 DOI: 10.1073/pnas.94.2.634  0.92
1996 Salazar-Mather TP, Ishikawa R, Biron CA. NK Cell Trafficking and Cytokine Expression in Splenic Compartments after IFN Induction and Viral Infection Journal of Immunology. 157: 3054-3064. PMID 8816415  0.92
1996 Wang B, Holländer GA, Nichogiannopoulou A, Simpson SJ, Orange JS, Gutierrez-Ramos JC, Burakoff SJ, Biron CA, Terhorst C. Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny International Immunology. 8: 939-949. PMID 8671683 DOI: 10.1093/intimm/8.6.939  0.92
1996 Orange JS, Biron CA. Characterization of early IL-12, IFN-αβ, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection Journal of Immunology. 156: 4746-4756. PMID 8648121  0.92
1996 Orange JS, Biron CA. An absolute and restricted requirement for IL-12 in natural killer cell IFN-γ production and antiviral defense: Studies of natural killer and T cell responses in contrasting viral infections Journal of Immunology. 156: 1138-1142. PMID 8557990  0.92
1996 Biron CA, Su HC, Orange JS. Function and regulation of natural killer (NK) cells during viral infections: Characterization of responses in vivo Methods: a Companion to Methods in Enzymology. 9: 379-393. DOI: 10.1006/meth.1996.0043  0.92
1996 Su C, Kulkarni AB, Karlsson S, Biron CA. Aberrant NK cell responses in TGF-β1-deficient mice Faseb Journal. 10.  0.92
1996 Cousens LP, Orange JS, Su HC, Biron CA. IFN-a/β inhibition of IL-12 and IFN-y production Faseb Journal. 10.  0.92
1995 Biron CA, Orange JS. IL 12 in acute viral infectious disease Research in Immunology. 146: 590-600. PMID 8839166 DOI: 10.1016/0923-2494(96)83036-7  0.92
1995 Orange JS, Salazar-Mather TP, Opal SM, Spencer RL, Miller AH, McEwen BS, Biron CA. Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids. The Journal of Experimental Medicine. 181: 901-14. PMID 7869050 DOI: 10.1084/jem.181.3.901  0.92
1995 Orange JS, Wang B, Terhorst C, Biron CA. Requirement for natural killer cell-produced interferon γ in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration Journal of Experimental Medicine. 182: 1045-1056. PMID 7561678 DOI: 10.1084/jem.182.4.1045  0.92
1995 Cousens LP, Orange JS, Biron CA. Endogenous IL-2 contributes to T cell expansion and IFN-γ production during lymphocytic choriomeningitis virus infection Journal of Immunology. 155: 5690-5699. PMID 7499855  0.92
1995 Biron CA, Gazzinelli RT. Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease outcome Current Opinion in Immunology. 7: 485-496. PMID 7495512 DOI: 10.1016/0952-7915(95)80093-X  0.92
1994 Su HC, Orange JS, Fast LD, Chan AT, Simpson SJ, Terhorst C, Biron CA. IL-2-dependent NK cell responses discovered in virus-infected β2-microglobulin-deficient mice Journal of Immunology. 153: 5674-5681. PMID 7989765  0.92
1994 Biron CA. Cytokines in the generation of immune responses to, and resolution of, virus infection Current Opinion in Immunology. 6: 530-538. PMID 7946039 DOI: 10.1016/0952-7915(94)90137-6  0.92
1994 Orange JS, Wolf SF, Biron CA. Effects of IL-12 on the response and susceptibility to experimental viral infections Journal of Immunology. 152: 1253-1264. PMID 7905500  0.92
1993 Su HC, Ishikawa R, Biron CA. Transforming growth factor-β expression and natural killer cell responses during virus infection of normal, nude, and SCID mice Journal of Immunology. 151: 4874-4890. PMID 8409446  0.92
1993 Ishikawa R, Biron CA. IFN induction and associated changes in splenic leukocyte distribution Journal of Immunology. 150: 3713-3727. PMID 7682583  0.92
1992 Moyer CF, Huggins E, Sarantopoulos S, Lewis JC, Sajuthi D, Biron CA, Reinisch CL. Cloned endothelium derived from autoimmune vascular disease retain structural and functional characteristics of normal endothelial cells. Experimental Cell Research. 199: 63-73. PMID 1735462 DOI: 10.1016/0014-4827(92)90462-H  0.92
1991 Su HC, Leite-Morris KA, Braun L, Biron CA. A role for transforming growth factor-β1 in regulating natural killer cell and T lymphocyte proliferative responses during acute infection with lymphocytic choriomeningitis virus Journal of Immunology. 147: 2717-2727. PMID 1918986  0.92
1991 Kasaian MT, Leite-Morris KA, Biron CA. The role of CD4+ cells in sustaining lymphocyte proliferation during lymphocytic choriomeningitis virus infection Journal of Immunology. 146: 1955-1963. PMID 1672337  0.92
1990 Kasaian MT, Biron CA. Effects of cyclosporin A on IL-2 production and lymphocyte proliferation during infection of mice with lymphocytic choriomeningitis virus Journal of Immunology. 144: 299-306. PMID 1967265  0.92
1990 Kasaian MT, Biron CA. Cyclosporin A inhibition of interleukin 2 gene expression, but not natural killer cell proliferation, after interferon induction in vivo Journal of Experimental Medicine. 171: 745-762. PMID 1689761  0.92
1990 Biron CA, Young HA, Kasaian MT. Interleukin 2-induced proliferation of murine natural killer cells in vivo Journal of Experimental Medicine. 171: 173-188. PMID 1688606  0.92
1989 Kasaian MT, Biron CA. The activation of IL-2 transcription in L3T4+ and LYT-2+ lymphocytes during virus infection in vivo Journal of Immunology. 142: 1287-1292. PMID 2783708  0.92
1989 Biron CA, Byron KS, Sullivan JL. Severe herpesvirus infections in an adolescent without natural killer cells New England Journal of Medicine. 320: 1731-1735. PMID 2543925  0.92
1988 McIntyre KW, Natuk RJ, Biron CA, Kase K, Greenberger J, Welsh RM. Blastogenesis of large granular lymphocytes in nonlymphoid organs Journal of Leukocyte Biology. 43: 492-501. PMID 2837525  0.92
1987 Biron CA, van Den Elsen P, Tutt MM, Medveczky P, Kumar V, Terhorst C. Murine natural killer cells stimulated in vivo do not express the T cell receptor α, β, γ, T3δ, or T3ε genes Journal of Immunology. 139: 1704-1710. PMID 3497976  0.92
1987 Biron CA, Pedersen KF, Welsh RM. Aberrant T cells in beige mutant mice Journal of Immunology. 138: 2050-2056. PMID 3494057  0.92
1986 Woda BA, Biron CA. Natural killer cell number and function in the spontaneously diabetic BB/W rat Journal of Immunology. 137: 1860-1866. PMID 3745917  0.92
1986 Biron CA, Pedersen KF, Welsh RM. Purification and target cell range of in vivo elicited blast natural killer cells Journal of Immunology. 137: 463-471. PMID 3722814  0.92
1986 Like AA, Biron CA, Weringer EJ, Byman K, Sroczynski E, Guberski DL. Prevention of diabetes in BioBreeding/Worcester rats with monoclonal antibodies that recognize T lymphocytes or natural killer cells Journal of Experimental Medicine. 164: 1145-1152. PMID 3531381  0.92
1986 Biron CA, Natuk RJ, Welsh RM. Generation of large granular T lymphocytes in vivo during viral infection Journal of Immunology. 136: 2280-2286. PMID 3485144  0.92
1985 Biron CA, Welsh RM. Blastogenesis of natural killer cell in vivo results in progeny cells with the capacity for continued proliferation Federation Proceedings. 44.  0.92
1984 Biron CA, Habu S, Okumura K, Welsh RM. Lysis of uninfected and virus-infected cells in vivo: A rejection mechanism in addition to that mediated by natural killer cells Journal of Virology. 50: 698-707. PMID 6374165  0.92
1984 Biron CA, Sonnenfeld G, Welsh RM. Interferon induces natural killer cell blastogenesis in vivo Journal of Leukocyte Biology. 35: 31-37. PMID 6200554  0.92
1984 LeBlanc PA, Biron CA. Mononuclear phagocyte maturation: A cytotoxic monoclonal antibody reactive with postmonoblast stages Cellular Immunology. 83: 242-254. PMID 6198098 DOI: 10.1016/0008-8749(84)90303-4  0.92
1984 Welsh RM, Biron CA, Bukowski JF, McIntyre KW, Yang H. Role of natural killer cells in virus infections of mice Survey and Synthesis of Pathology Research. 3: 409-431. PMID 6084280  0.92
1984 Biron CA, Welsh RM. Two mechanisms of in vivo lysis activated in the lungs during viral infection Federation Proceedings. 43.  0.92
1983 Biron CA, Turgiss LR, Welsh RM. Increase in NK cell number and turnover rate during acute viral infection Journal of Immunology. 131: 1539-1545. PMID 6886424  0.92
1983 Bukowski JF, Biron CA, Welsh RM. Elevated natural killer cell-mediated cytotoxicity, plasma interferon, and tumor cell rejection in mice persistently infected with lymphocytic choriomeningitis virus Journal of Immunology. 131: 991-996. PMID 6190947  0.92
1982 Biron CA, Welsh RM. Blastogenesis of natural killer cells during viral infection in vivo Journal of Immunology. 129: 2788-2795. PMID 7142707  0.92
1982 Biron CA, Welsh RM. Activation and role of natural killer cells in virus infections Medical Microbiology and Immunology. 170: 155-172. PMID 6176843 DOI: 10.1007/BF02298196  0.92
1981 Biron CA, Hutt-Fletcher LM, Wertz GT, Pagano JS. Interferon production and activation of non-specific effector cells by stimulation with lymphoblastoid cell lines in vitro International Journal of Cancer. 27: 185-190. PMID 6169656  0.92
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