Charles A. Scanga, Ph.D. - Publications

Affiliations: 
2000 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Microbiology Biology, Immunology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hartman AL, Nambulli S, McMillen CM, White AG, Tilston-Lunel NL, Albe JR, Cottle E, Dunn MD, Frye LJ, Gilliland TH, Olsen EL, O'Malley KJ, Schwarz MM, Tomko JA, Walker RC, ... ... Scanga CA, et al. SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts. Plos Pathogens. 16: e1008903. PMID 32946524 DOI: 10.1371/journal.ppat.1008903  0.92
2020 Kim S, Scanga CA, Miranda Silva C, Zimmerman M, Causgrove C, Stein B, Dartois V, Peloquin CA, Graham E, Louie A, Flynn JL, Schmidt S, Drusano GL. Pharmacokinetics of tedizolid, sutezolid, and sutezolid-M1 in non-human primates. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105421. PMID 32531349 DOI: 10.1016/j.ejps.2020.105421  0.92
2020 Ellis AL, Balgeman AJ, Larson EC, Rodgers MA, Ameel C, Baranowski T, Kannal N, Maiello P, Juno JA, Scanga CA, O'Connor SL. MAIT cells are functionally impaired in a Mauritian cynomolgus macaque model of SIV and Mtb co-infection. Plos Pathogens. 16: e1008585. PMID 32433713 DOI: 10.1371/journal.ppat.1008585  0.4
2020 Darrah PA, Zeppa JJ, Maiello P, Hackney JA, Wadsworth MH, Hughes TK, Pokkali S, Swanson PA, Grant NL, Rodgers MA, Kamath M, Causgrove CM, Laddy DJ, Bonavia A, Casimiro D, ... ... Scanga CA, et al. Prevention of tuberculosis in macaques after intravenous BCG immunization. Nature. 577: 95-102. PMID 31894150 DOI: 10.1038/s41586-019-1817-8  0.92
2019 Darrah PA, DiFazio RM, Maiello P, Gideon HP, Myers AJ, Rodgers MA, Hackney JA, Lindenstrom T, Evans T, Scanga CA, Prikhodko V, Andersen P, Lin PL, Laddy D, Roederer M, et al. Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques. Npj Vaccines. 4: 21. PMID 31149352 DOI: 10.1038/s41541-019-0113-9  0.92
2018 Rodgers MA, Ameel C, Ellis-Connell AL, Balgeman AJ, Maiello P, Barry GL, Friedrich TC, Klein E, O'Connor SL, Scanga CA. Pre-existing SIV Infection Increases Susceptibility to Tuberculosis in Mauritian Cynomolgus Macaques. Infection and Immunity. PMID 30224552 DOI: 10.1128/IAI.00565-18  0.4
2018 Mellors TR, Nasir M, Franchina FA, Smolinska A, Blanchet L, Flynn J, Tomko JA, O'Malley MJ, Scanga CA, Lin PL, Wagner J, Hill JE. Identification of Mycobacterium tuberculosis using volatile biomarkers in culture and exhaled breath. Journal of Breath Research. PMID 29910196 DOI: 10.1088/1752-7163/aacd18  0.4
2017 Maiello P, DiFazio RM, Cadena AM, Rodgers MA, Lin PL, Scanga CA, Flynn JL. Rhesus macaques are more susceptible to progressive tuberculosis than cynomolgus macaques: A quantitative comparison. Infection and Immunity. PMID 28947646 DOI: 10.1128/IAI.00505-17  0.92
2017 White AG, Maiello P, Coleman MT, Tomko JA, Frye LJ, Scanga CA, Lin PL, Flynn JL. Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates. Journal of Visualized Experiments : Jove. PMID 28930979 DOI: 10.3791/56375  0.92
2017 Mattila JT, Beaino W, Maiello P, Coleman MT, White AG, Scanga CA, Flynn JL, Anderson CJ. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1-Expressing Immune Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 28592427 DOI: 10.4049/jimmunol.1700231  0.92
2017 Rockwood N, Costa DL, Amaral EP, Du Bruyn E, Kubler A, Gil-Santana L, Fukutani KF, Scanga CA, Flynn JL, Jackson SH, Wilkinson KA, Bishai WR, Sher A, Wilkinson RJ, Andrade BB. Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes. Frontiers in Immunology. 8: 542. PMID 28553288 DOI: 10.3389/fimmu.2017.00542  0.92
2017 Ellis A, Balgeman A, Rodgers M, Updike C, Tomko J, Maiello P, Scanga CA, O'Connor SL. Characterization of T cells specific for CFP-10 and ESAT-6 in M. tuberculosis-infected Mauritian Cynomolgus Macaques. Infection and Immunity. PMID 28115506 DOI: 10.1128/IAI.01009-16  0.4
2017 Wonderlich ER, Swan ZD, Bissel SJ, Hartman AL, Carney JP, O'Malley KJ, Obadan AO, Santos J, Walker R, Sturgeon TJ, Frye LJ, Maiello P, Scanga CA, Bowling JD, Bouwer AL, et al. Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques. Journal of Immunology (Baltimore, Md. : 1950). PMID 28062701 DOI: 10.4049/jimmunol.1601770  0.92
2017 Mellors TR, Blanchet L, Flynn JL, Tomko J, O'Malley M, Scanga CA, Lin PL, Hill JE. A new method to evaluate macaque health using exhaled breath: A case study of M. tuberculosis in a BSL-3 setting. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00888.2016. PMID 28057819 DOI: 10.1152/japplphysiol.00888.2016  0.92
2015 Levine DM, Dutta NK, Eckels J, Scanga C, Stein C, Mehra S, Kaushal D, Karakousis PC, Salamon H. A tuberculosis ontology for host systems biology. Tuberculosis (Edinburgh, Scotland). 95: 570-4. PMID 26190839 DOI: 10.1016/j.tube.2015.05.012  0.92
2014 Coleman MT, Chen RY, Lee M, Lin PL, Dodd LE, Maiello P, Via LE, Kim Y, Marriner G, Dartois V, Scanga C, Janssen C, Wang J, Klein E, Cho SN, et al. PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis. Science Translational Medicine. 6: 265ra167. PMID 25473035 DOI: 10.1126/scitranslmed.3009500  0.92
2014 Scanga CA, Flynn JL. Modeling tuberculosis in nonhuman primates. Cold Spring Harbor Perspectives in Medicine. 4: a018564. PMID 25213189 DOI: 10.1101/cshperspect.a018564  0.92
2014 Darrah PA, Bolton DL, Lackner AA, Kaushal D, Aye PP, Mehra S, Blanchard JL, Didier PJ, Roy CJ, Rao SS, Hokey DA, Scanga CA, Sizemore DR, Sadoff JC, Roederer M, et al. Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge. Journal of Immunology (Baltimore, Md. : 1950). 193: 1799-811. PMID 25024382 DOI: 10.4049/jimmunol.1400676  0.92
2014 Scanga CA, Lopresti BJ, Tomko J, Frye LJ, Coleman TM, Fillmore D, Carney JP, Lin PL, Flynn JL, Gardner CL, Sun C, Klimstra WB, Ryman KD, Reed DS, Fisher DJ, et al. In vivo imaging in an ABSL-3 regional biocontainment laboratory. Pathogens and Disease. 71: 207-12. PMID 24838691 DOI: 10.1111/2049-632X.12186  0.92
2013 Lin PL, Coleman T, Carney JP, Lopresti BJ, Tomko J, Fillmore D, Dartois V, Scanga C, Frye LJ, Janssen C, Klein E, Barry CE, Flynn JL. Radiologic responses in cynomolgous macaques for assessing tuberculosis chemotherapy regimens. Antimicrobial Agents and Chemotherapy. PMID 23796926 DOI: 10.1128/AAC.00277-13  0.92
2012 Rahman S, Magalhaes I, Rahman J, Ahmed RK, Sizemore DR, Scanga CA, Weichold F, Verreck F, Kondova I, Sadoff J, Thorstensson R, Spångberg M, Svensson M, Andersson J, Maeurer M, et al. Prime-boost vaccination with rBCG/rAd35 enhances CD8⁺ cytolytic T-cell responses in lesions from Mycobacterium tuberculosis-infected primates. Molecular Medicine (Cambridge, Mass.). 18: 647-58. PMID 22396020 DOI: 10.2119/molmed.2011.00222  0.92
2010 Scanga CA, Flynn JL. Mycobacterial infections and the inflammatory seesaw. Cell Host & Microbe. 7: 177-9. PMID 20227659 DOI: 10.1016/j.chom.2010.03.003  0.92
2009 Sun R, Skeiky YA, Izzo A, Dheenadhayalan V, Imam Z, Penn E, Stagliano K, Haddock S, Mueller S, Fulkerson J, Scanga C, Grover A, Derrick SC, Morris S, Hone DM, et al. Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis. Vaccine. 27: 4412-23. PMID 19500523 DOI: 10.1016/j.vaccine.2009.05.048  0.92
2008 Magalhaes I, Sizemore DR, Ahmed RK, Mueller S, Wehlin L, Scanga C, Weichold F, Schirru G, Pau MG, Goudsmit J, Kühlmann-Berenzon S, Spångberg M, Andersson J, Gaines H, Thorstensson R, et al. rBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector. Plos One. 3: e3790. PMID 19023426 DOI: 10.1371/journal.pone.0003790  0.92
2007 Lee KS, Scanga CA, Bachelder EM, Chen Q, Snapper CM. TLR2 synergizes with both TLR4 and TLR9 for induction of the MyD88-dependent splenic cytokine and chemokine response to Streptococcus pneumoniae. Cellular Immunology. 245: 103-10. PMID 17521621 DOI: 10.1016/j.cellimm.2007.04.003  0.92
2007 Scanga CA, Bafica A, Sher A. Viral gene expression in HIV transgenic mice is activated by Mycobacterium tuberculosis and suppressed after antimycobacterial chemotherapy. The Journal of Infectious Diseases. 195: 246-54. PMID 17191170 DOI: 10.1086/510244  0.92
2005 Bafica A, Scanga CA, Feng CG, Leifer C, Cheever A, Sher A. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. The Journal of Experimental Medicine. 202: 1715-24. PMID 16365150 DOI: 10.1084/jem.20051782  0.92
2005 Bafica A, Scanga CA, Serhan C, Machado F, White S, Sher A, Aliberti J. Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production. The Journal of Clinical Investigation. 115: 1601-6. PMID 15931391 DOI: 10.1172/JCI23949  0.92
2005 Feng CG, Jankovic D, Kullberg M, Cheever A, Scanga CA, Hieny S, Caspar P, Yap GS, Sher A. Maintenance of pulmonary Th1 effector function in chronic tuberculosis requires persistent IL-12 production. Journal of Immunology (Baltimore, Md. : 1950). 174: 4185-92. PMID 15778379  0.92
2004 Báfica A, Scanga CA, Schito M, Chaussabel D, Sher A. Influence of coinfecting pathogens on HIV expression: evidence for a role of Toll-like receptors. Journal of Immunology (Baltimore, Md. : 1950). 172: 7229-34. PMID 15187096  0.92
2004 Scanga CA, Bafica A, Feng CG, Cheever AW, Hieny S, Sher A. MyD88-deficient mice display a profound loss in resistance to Mycobacterium tuberculosis associated with partially impaired Th1 cytokine and nitric oxide synthase 2 expression. Infection and Immunity. 72: 2400-4. PMID 15039368 DOI: 10.1128/IAI.72.4.2400-2404.2004  0.92
2004 Báfica A, Scanga CA, Equils O, Sher A. The induction of Toll-like receptor tolerance enhances rather than suppresses HIV-1 gene expression in transgenic mice. Journal of Leukocyte Biology. 75: 460-6. PMID 14657211 DOI: 10.1189/jlb.0803388  0.92
2003 Lazarevic V, Myers AJ, Scanga CA, Flynn JL. CD40, but not CD40L, is required for the optimal priming of T cells and control of aerosol M. tuberculosis infection. Immunity. 19: 823-35. PMID 14670300 DOI: 10.1016/S1074-7613(03)00324-8  0.92
2003 Feng CG, Scanga CA, Collazo-Custodio CM, Cheever AW, Hieny S, Caspar P, Sher A. Mice lacking myeloid differentiation factor 88 display profound defects in host resistance and immune responses to Mycobacterium avium infection not exhibited by Toll-like receptor 2 (TLR2)- and TLR4-deficient animals. Journal of Immunology (Baltimore, Md. : 1950). 171: 4758-64. PMID 14568952  0.92
2003 Báfica A, Scanga CA, Schito ML, Hieny S, Sher A. Cutting edge: in vivo induction of integrated HIV-1 expression by mycobacteria is critically dependent on Toll-like receptor 2. Journal of Immunology (Baltimore, Md. : 1950). 171: 1123-7. PMID 12874196  0.92
2002 Brennan PJ, Terwilliger T, Barry CE, Manca C, Su H, Reed M, Rutter K, Domenech P, Kaplan G, Li YJ, Wagner D, Bermudez LE, Bodnar K, Flynn J, Campos-Neto A, ... ... Scanga C, et al. The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th annual research conference, New Orleans, Louisiana, USA, 15-17 July 2001 Tuberculosis. 82: 113-135. PMID 12408170 DOI: 10.1054/tube.2002.0329  0.92
2002 Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A. Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 5997-6001. PMID 12055206  0.92
2001 Scanga CA, Mohan VP, Tanaka K, Alland D, Flynn JL, Chan J. The inducible nitric oxide synthase locus confers protection against aerogenic challenge of both clinical and laboratory strains of Mycobacterium tuberculosis in mice. Infection and Immunity. 69: 7711-7. PMID 11705952 DOI: 10.1128/IAI.69.12.7711-7717.2001  0.92
2001 Mohan VP, Scanga CA, Yu K, Scott HM, Tanaka KE, Tsang E, Tsai MM, Flynn JL, Chan J. Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology. Infection and Immunity. 69: 1847-55. PMID 11179363 DOI: 10.1128/IAI.69.3.1847-1855.2001  0.92
2000 Scanga CA, Mohan VP, Yu K, Joseph H, Tanaka K, Chan J, Flynn JL. Depletion of CD4(+) T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon gamma and nitric oxide synthase 2. The Journal of Experimental Medicine. 192: 347-58. PMID 10934223 DOI: 10.1084/jem.192.3.347  0.92
2000 Serbina NV, Liu CC, Scanga CA, Flynn JL. CD8+ CTL from lungs of Mycobacterium tuberculosis-infected mice express perforin in vivo and lyse infected macrophages. Journal of Immunology (Baltimore, Md. : 1950). 165: 353-63. PMID 10861072  0.92
1999 Scanga CA, Mohan VP, Joseph H, Yu K, Chan J, Flynn JL. Reactivation of latent tuberculosis: variations on the Cornell murine model. Infection and Immunity. 67: 4531-8. PMID 10456896  0.92
1998 Flynn JL, Scanga CA, Tanaka KE, Chan J. Effects of aminoguanidine on latent murine tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 160: 1796-803. PMID 9469439  0.92
1996 Gagneten S, Scanga CA, Dveksler GS, Beauchemin N, Percy D, Holmes KV. Attachment glycoproteins and receptor specificity of rat coronaviruses Laboratory Animal Science. 46: 159-166. PMID 8723231  0.92
1996 Dveksler GS, Gagneten SE, Scanga CA, Cardellichio CB, Holmes KV. Expression of the recombinant anchorless N-terminal domain of mouse hepatitis virus (MHV) receptor makes hamster or human cells susceptible to MHV infection Journal of Virology. 70: 4142-4145. PMID 8648757  0.92
1995 Levis R, Cardellichio CB, Scanga CA, Compton SR, Holmes KV. Multiple receptor-dependent steps determine the species specificity of HCV-229E infection Advances in Experimental Medicine and Biology. 380: 337-343. PMID 8830504  0.92
1995 Montali RJ, Connolly BM, Armstrong DL, Scanga CA, Holmes KV. Pathology and immunohistochemistry of callitrichid hepatitis, an emerging disease of captive New World primates caused by lymphocytic choriomeningitis virus. The American Journal of Pathology. 147: 1441-9. PMID 7485406  0.92
1993 Scanga CA, Holmes KV, Montali RJ. Serologic evidence of infection with lymphocytic choriomeningitis virus, the agent of callitrichid hepatitis, in primates in zoos, primate research centers, and a natural reserve J.Zoo Wildl.Med.. 24: 469-474.  0.92
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