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Luz D. Orozco, Ph.D. - Publications

Affiliations: 
2011 University of California, Los Angeles, Los Angeles, CA 
Area:
Genetics, Bioinformatics Biology, Systematic Biology
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Bhetraratana M, Orozco LD, Bennett BJ, Luna K, Yang X, Lusis AJ, Araujo JA. Diesel exhaust particle extract elicits an oxPAPC-like transcriptomic profile in macrophages across multiple mouse strains. Environmental Pollution (Barking, Essex : 1987). 124415. PMID 38908672 DOI: 10.1016/j.envpol.2024.124415  0.691
2022 den Hollander AI, Mullins RF, Orozco LD, Voigt AP, Chen HH, Strunz T, Grassmann F, Haines JL, Kuiper JJW, Tumminia SJ, Allikmets R, Hageman GS, Stambolian D, Klaver CCW, Boeke JD, et al. Systems genomics in age-related macular degeneration. Experimental Eye Research. 109248. PMID 36108770 DOI: 10.1016/j.exer.2022.109248  0.379
2019 Bhetraratana M, Orozco LD, Hong J, Diamante G, Majid S, Bennett BJ, Ahn IS, Yang X, Lusis AJ, Araujo JA. Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies. Archives of Biochemistry and Biophysics. 108116. PMID 31568751 DOI: 10.1016/J.Abb.2019.108116  0.704
2018 Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, et al. Epigenome-wide association in adipose tissue from the METSIM cohort. Human Molecular Genetics. PMID 29893869 DOI: 10.1093/Hmg/Ddy205  0.418
2018 Orozco LD, Farrell C, Hale C, Rbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, et al. Epigenome-wide association in adipose tissue from the METSIM cohort. Human Molecular Genetics. PMID 29566149 DOI: 10.1093/Hmg/Ddy093  0.515
2017 Lupu DS, Orozco LD, Wang Y, Cullen JM, Pellegrini M, Zeisel SH. Altered methylation of specific DNA loci in the liver of Bhmt-null mice results in repression of Iqgap2 and F2rl2 and is associated with development of preneoplastic foci. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28179424 DOI: 10.1096/Fj.201601169R  0.457
2016 Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Mäkinen VP, Yang X. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems. Bmc Genomics. 17: 874. PMID 27814671 DOI: 10.1186/S12864-016-3198-9  0.429
2016 Meng Q, Ying Z, Noble E, Zhao Y, Agrawal R, Mikhail A, Zhuang Y, Tyagi E, Zhang Q, Lee JH, Morselli M, Orozco L, Guo W, Kilts TM, Zhu J, et al. Systems Nutrigenomics Reveals Brain Gene Networks Linking Metabolic and Brain Disorders. Ebiomedicine. 7: 157-166. PMID 27322469 DOI: 10.1016/J.Ebiom.2016.04.008  0.375
2016 Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Sevag Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, et al. Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. Plos Genetics. 12: e1005913. PMID 26934746 DOI: 10.1371/journal.pgen.1005913  0.495
2016 Chen H, Orozco LD, Wang J, Rau CD, Rubbi L, Ren S, Wang Y, Pellegrini M, Lusis AJ, Vondriska TM. DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States. Circulation Research. PMID 26838786 DOI: 10.1161/Circresaha.115.305298  0.659
2015 Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, et al. Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. Plos Genetics. 11: e1005711. PMID 26694027 DOI: 10.1371/Journal.Pgen.1005711  0.645
2015 Orozco LD, Morselli M, Rubbi L, Guo W, Go J, Shi H, Lopez D, Furlotte NA, Bennett BJ, Farber CR, Ghazalpour A, Zhang MQ, Bahous R, Rozen R, Lusis AJ, et al. Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice. Cell Metabolism. 21: 905-17. PMID 26039453 DOI: 10.1016/J.Cmet.2015.04.025  0.748
2014 Orozco LD, Rubbi L, Martin LJ, Fang F, Hormozdiari F, Che N, Smith AD, Lusis AJ, Pellegrini M. Intergenerational genomic DNA methylation patterns in mouse hybrid strains. Genome Biology. 15: R68. PMID 24887417 DOI: 10.1186/Gb-2014-15-5-R68  0.57
2014 Ghazalpour A, Bennett BJ, Shih D, Che N, Orozco L, Pan C, Hagopian R, He A, Kayne P, Yang WP, Kirchgessner T, Lusis AJ. Genetic regulation of mouse liver metabolite levels. Molecular Systems Biology. 10: 730. PMID 24860088 DOI: 10.15252/Msb.20135004  0.769
2013 Heinz S, Romanoski CE, Benner C, Allison KA, Kaikkonen MU, Orozco LD, Glass CK. Effect of natural genetic variation on enhancer selection and function. Nature. 503: 487-92. PMID 24121437 DOI: 10.1038/Nature12615  0.686
2013 Chen PY, Ganguly A, Rubbi L, Orozco LD, Morselli M, Ashraf D, Jaroszewicz A, Feng S, Jacobsen SE, Nakano A, Devaskar SU, Pellegrini M. Intrauterine calorie restriction affects placental DNA methylation and gene expression. Physiological Genomics. 45: 565-76. PMID 23695884 DOI: 10.1152/Physiolgenomics.00034.2013  0.44
2013 Rau CD, Wisniewski N, Orozco LD, Bennett B, Weiss J, Lusis AJ. Maximal information component analysis: a novel non-linear network analysis method. Frontiers in Genetics. 4: 28. PMID 23487572 DOI: 10.3389/Fgene.2013.00028  0.646
2013 Davis RC, van Nas A, Bennett B, Orozco L, Pan C, Rau CD, Eskin E, Lusis AJ. Genome-wide association mapping of blood cell traits in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 105-18. PMID 23417284 DOI: 10.1007/S00335-013-9448-0  0.781
2012 Calabrese G, Bennett BJ, Orozco L, Kang HM, Eskin E, Dombret C, De Backer O, Lusis AJ, Farber CR. Systems genetic analysis of osteoblast-lineage cells. Plos Genetics. 8: e1003150. PMID 23300464 DOI: 10.1371/Journal.Pgen.1003150  0.582
2012 Orozco LD, Bennett BJ, Farber CR, Ghazalpour A, Pan C, Che N, Wen P, Qi HX, Mutukulu A, Siemers N, Neuhaus I, Yordanova R, Gargalovic P, Pellegrini M, Kirchgessner T, et al. Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages. Cell. 151: 658-70. PMID 23101632 DOI: 10.1016/J.Cell.2012.08.043  0.753
2012 Kim JB, Deluna A, Mungrue IN, Vu C, Pouldar D, Civelek M, Orozco L, Wu J, Wang X, Charugundla S, Castellani LW, Rusek M, Jakubowski H, Jakobowski H, Lusis AJ. Effect of 9p21.3 coronary artery disease locus neighboring genes on atherosclerosis in mice. Circulation. 126: 1896-906. PMID 22952318 DOI: 10.1161/Circulationaha.111.064881  0.555
2012 Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, et al. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 680-92. PMID 22892838 DOI: 10.1007/S00335-012-9411-5  0.749
2012 Bennett BJ, Orozco L, Kostem E, Erbilgin A, Dallinga M, Neuhaus I, Guan B, Wang X, Eskin E, Lusis AJ. High-resolution association mapping of atherosclerosis loci in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1790-8. PMID 22723443 DOI: 10.1161/Atvbaha.112.253864  0.782
2011 Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG, et al. Comparative analysis of proteome and transcriptome variation in mouse. Plos Genetics. 7: e1001393. PMID 21695224 DOI: 10.1371/Journal.Pgen.1001393  0.732
2011 Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, et al. Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. Plos Genetics. 7: e1002038. PMID 21490954 DOI: 10.1371/Journal.Pgen.1002038  0.754
2011 Barajas B, Che N, Yin F, Rowshanrad A, Orozco LD, Gong KW, Wang X, Castellani LW, Reue K, Lusis AJ, Araujo JA. NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 58-66. PMID 20947826 DOI: 10.1161/Atvbaha.110.210906  0.61
2010 Bennett BJ, Farber CR, Orozco L, Kang HM, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, et al. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Research. 20: 281-90. PMID 20054062 DOI: 10.1101/Gr.099234.109  0.76
2009 Orozco LD, Cokus SJ, Ghazalpour A, Ingram-Drake L, Wang S, van Nas A, Che N, Araujo JA, Pellegrini M, Lusis AJ. Copy number variation influences gene expression and metabolic traits in mice. Human Molecular Genetics. 18: 4118-29. PMID 19648292 DOI: 10.1093/Hmg/Ddp360  0.748
2007 Orozco LD, Kapturczak MH, Barajas B, Wang X, Weinstein MM, Wong J, Deshane J, Bolisetty S, Shaposhnik Z, Shih DM, Agarwal A, Lusis AJ, Araujo JA. Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis. Circulation Research. 100: 1703-11. PMID 17495224 DOI: 10.1161/Circresaha.107.151720  0.647
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