| Year |
Citation |
Score |
| 2024 |
Lékó AH, Gregory-Flores A, Marchette RCN, Gomez JL, Vendruscolo JCM, Repunte-Canonigo V, Choung V, Deschaine SL, Whiting KE, Jackson SN, Cornejo MP, Perello M, You ZB, Eckhaus M, Rasineni K, ... Janda KD, et al. Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Communications Biology. 7: 632. PMID 38796563 DOI: 10.1038/s42003-024-06303-5 |
0.304 |
|
| 2024 |
Lee JC, Shirey RJ, Turner LD, Park H, Lairson LL, Janda KD. Discovery of PLD4 modulators by high-throughput screening and kinetic analysis. Results in Chemistry. 7. PMID 38560090 DOI: 10.1016/j.rechem.2024.101349 |
0.756 |
|
| 2023 |
Leggio L, Leko A, Gregory-Flores A, Marchette R, Gomez J, Vendruscolo J, Repunte-Canonigo V, Chuong V, Deschaine S, Whiting K, Jackson S, Cornejo M, Perello M, You ZB, Eckhaus M, ... Janda K, et al. Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Research Square. PMID 37886546 DOI: 10.21203/rs.3.rs-3236045/v1 |
0.303 |
|
| 2023 |
Richardson RS, Sulima A, Rice KC, Kucharczk JA, Janda KD, Nisbett KE, Koob GF, Vendruscolo LF, Leggio L. Pharmacological GHSR (ghrelin receptor) blockade reduces alcohol binge-like drinking in male and female mice. Neuropharmacology. 109643. PMID 37369277 DOI: 10.1016/j.neuropharm.2023.109643 |
0.314 |
|
| 2023 |
Lin L, Patel EN, Nielsen AL, Turner LD, Tepp WH, Nguyen K, Pellett S, Janda K. Transformation of a Metal Chelate into a "Catch and Anchor" Inhibitor of Botulinum A Protease. International Journal of Molecular Sciences. 24. PMID 36901734 DOI: 10.3390/ijms24054303 |
0.782 |
|
| 2022 |
Lee JC, Eubanks LM, Zhou B, Janda KD. Development of an Effective Monoclonal Antibody against Heroin and Its Metabolites Reveals Therapies Have Mistargeted 6-Monoacetylmorphine and Morphine over Heroin. Acs Central Science. 8: 1464-1470. PMID 36313156 DOI: 10.1021/acscentsci.2c00977 |
0.78 |
|
| 2022 |
Patel EN, Lin L, Sneller MM, Eubanks LM, Tepp WH, Pellett S, Janda KD. Investigation of Salicylanilides as Botulinum Toxin Antagonists. Acs Infectious Diseases. PMID 35877209 DOI: 10.1021/acsinfecdis.2c00230 |
0.789 |
|
| 2022 |
Patel EN, Turner LD, Hixon MS, Janda KD. Identification of Slow-Binding Inhibitors of the BoNT/A Protease. Acs Medicinal Chemistry Letters. 13: 742-747. PMID 35450355 DOI: 10.1021/acsmedchemlett.2c00028 |
0.776 |
|
| 2022 |
Lee JC, Park H, Eubanks LM, Ellis B, Zhou B, Janda KD. A Vaccine against Benzimidazole-Derived New Psychoactive Substances That Are More Potent Than Fentanyl. Journal of Medicinal Chemistry. PMID 34994550 DOI: 10.1021/acs.jmedchem.1c01967 |
0.754 |
|
| 2021 |
Lee JC, Janda KD. Development of effective therapeutics for polysubstance use disorders. Current Opinion in Chemical Biology. 66: 102105. PMID 34936944 DOI: 10.1016/j.cbpa.2021.102105 |
0.767 |
|
| 2021 |
Staples MC, Herman MA, Lockner JW, Avchalumov Y, Kharidia KM, Janda KD, Roberto M, Mandyam CD. Isoxazole-9 reduces enhanced fear responses and retrieval in ethanol-dependent male rats. Journal of Neuroscience Research. PMID 34496069 DOI: 10.1002/jnr.24932 |
0.729 |
|
| 2021 |
Lin M, Lee JC, Blake S, Ellis B, Eubanks LM, Janda KD. Broadly Neutralizing Synthetic Cannabinoid Vaccines. Jacs Au. 1: 31-40. PMID 34467269 DOI: 10.1021/jacsau.0c00057 |
0.785 |
|
| 2021 |
Lee JC, Janda KD. Immunopharmacotherapeutic advancements in addressing methamphetamine abuse. Rsc Chemical Biology. 2: 77-93. PMID 34458776 DOI: 10.1039/d0cb00165a |
0.767 |
|
| 2021 |
Turner LD, Nielsen AL, Lin L, Campedelli AJ, Silvaggi NR, Chen JS, Wakefield AE, Allen KN, Janda KD. Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease. Acs Medicinal Chemistry Letters. 12: 1318-1324. PMID 34413962 DOI: 10.1021/acsmedchemlett.1c00325 |
0.718 |
|
| 2021 |
Turner LD, Nielsen AL, Lin L, Pellett S, Sugane T, Olson ME, Johnson EA, Janda KD. Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach. Rsc Medicinal Chemistry. 12: 960-969. PMID 34223161 DOI: 10.1039/d1md00089f |
0.726 |
|
| 2021 |
Shirey RJ, Hart JR, Sridharan B, Novick SJ, Turner LD, Zhou B, Nielsen AL, Eubanks LM, Ueno L, Hixon MS, Lairson LL, Spicer TP, Scampavia LD, Griffin PR, Vogt PK, ... Janda KD, et al. Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay. Bioorganic & Medicinal Chemistry. 42: 116246. PMID 34130216 DOI: 10.1016/j.bmc.2021.116246 |
0.723 |
|
| 2021 |
Turner LD, Nielsen AL, Lin L, Pellett S, Sugane T, Olson ME, Janda KD. COVALENT INHIBITION OF BOTULINUM NEUROTOXIN A - EXPLORATION OF WARHEAD REACTIVITY AND FUNCTION USING A BIFUNCTIONAL APPROACH. Toxicon : Official Journal of the International Society On Toxinology. 190: S72-S73. PMID 34103769 |
0.708 |
|
| 2021 |
Park H, Lee JC, Eubanks LM, Ellis B, Zhou B, Janda KD. Improvements on a chemically contiguous hapten for a vaccine to address fentanyl-contaminated heroin. Bioorganic & Medicinal Chemistry. 41: 116225. PMID 34034147 DOI: 10.1016/j.bmc.2021.116225 |
0.769 |
|
| 2021 |
Rayo J, Gregor R, Jacob NT, Dandela R, Dubinsky L, Yashkin A, Aranovich A, Thangaraj M, Ernst O, Barash E, Malitsky S, Florea BI, Krom BP, Wiemer EAC, Kickhoefer VA, ... ... Janda KD, et al. Immunoediting role for major vault protein in apoptotic signaling induced by bacterial -acyl homoserine lactones. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33723037 DOI: 10.1073/pnas.2012529118 |
0.353 |
|
| 2020 |
Kyzer JL, McGuire M, Park H, Belz TF, Bonakdar R, Janda KD, Wenthur CJ. Anti-Opioid Antibodies in Individuals Using Chronic Opioid Therapy for Lower Back Pain. Acs Pharmacology & Translational Science. 3: 896-906. PMID 33073189 DOI: 10.1021/acsptsci.0c00057 |
0.676 |
|
| 2020 |
Lin L, Olson ME, Sugane T, Turner LD, Tararina MA, Nielsen AL, Kurbanov EK, Pellett S, Johnson EA, Cohen SM, Allen KN, Janda KD. A Catch and Anchor Approach to Combat both Toxicity and Longevity of Botulinum Toxin A. Journal of Medicinal Chemistry. PMID 32886509 DOI: 10.1021/Acs.Jmedchem.0C01006 |
0.739 |
|
| 2020 |
Belz TF, Bremer PT, Zhou B, Blake S, Ellis B, Eubanks LM, Janda KD. Sulfonate-isosteric replacement examined within heroin-hapten vaccine design. Bioorganic & Medicinal Chemistry Letters. 30: 127388. PMID 32738981 DOI: 10.1016/J.Bmcl.2020.127388 |
0.323 |
|
| 2020 |
Belz TF, Bremer PT, Zhou B, Ellis B, Eubanks LM, Janda KD. Enhancement of a Heroin Vaccine Through Hapten Deuteration. Journal of the American Chemical Society. PMID 32700530 DOI: 10.1021/Jacs.0C05219 |
0.351 |
|
| 2020 |
Wang J, Ellis B, Zhou B, Eubanks LM, Blake S, Janda KD. A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1-3Gal epitope. Chemical Communications (Cambridge, England). PMID 32396160 DOI: 10.1039/D0Cc02107E |
0.364 |
|
| 2020 |
Townsend EA, Bremer P, Faunce K, Negus SS, Jaster A, Robinson H, Janda KD, Banks ML. Evaluation of a dual fentanyl/heroin vaccine on the antinociceptive and reinforcing effects of a fentanyl/heroin mixture in male and female rats. Acs Chemical Neuroscience. PMID 32271538 DOI: 10.1021/Acschemneuro.0C00064 |
0.32 |
|
| 2020 |
Lee JC, Kim HY, Lee S, Shin J, Kim HV, Kim K, Baek S, Lee D, Jeon H, Kim D, Yang SH, Han G, Park K, Choi J, Park J, ... ... Janda KD, et al. Discovery of chemicals to clear or indicate amyloid aggregates by targeting memory-impairing anti-parallel Aβ dimers. Angewandte Chemie (International Ed. in English). PMID 32233096 DOI: 10.1002/Anie.202002574 |
0.762 |
|
| 2020 |
Natori Y, Janda KD. Synthesis of Drug Vaccine against Heroin Contaminated with Fentanyl and Their Biological Evaluation Journal of Synthetic Organic Chemistry Japan. 78: 875-885. DOI: 10.5059/Yukigoseikyokaishi.78.875 |
0.316 |
|
| 2019 |
Olson ME, Sugane T, Zhou B, Janda KD. Consequence of Hapten Stereochemistry: An Efficacious Methamphetamine Vaccine. Journal of the American Chemical Society. 141: 14089-14092. PMID 31479256 DOI: 10.1021/Jacs.9B07294 |
0.365 |
|
| 2019 |
Tenney RD, Blake S, Bremer PT, Zhou B, Hwang CS, Poklis JL, Janda KD, Banks ML. Vaccine blunts fentanyl potency in male rhesus monkeys. Neuropharmacology. 107730. PMID 31369740 DOI: 10.1016/J.Neuropharm.2019.107730 |
0.324 |
|
| 2019 |
Lin L, Olson ME, Eubanks LM, Janda KD. Strategies to Counteract Botulinum Neurotoxin A: Nature's Deadliest Biomolecule. Accounts of Chemical Research. PMID 31322847 DOI: 10.1021/Acs.Accounts.9B00261 |
0.325 |
|
| 2019 |
Smith LC, Bremer PT, Hwang CS, Zhou B, Ellis B, Hixon MS, Janda KD. Monoclonal Antibodies for Combating Synthetic Opioid Intoxication. Journal of the American Chemical Society. PMID 31187995 DOI: 10.1021/Jacs.9B04872 |
0.323 |
|
| 2019 |
Hwang CS, Smith LC, Wenthur CJ, Ellis B, Zhou B, Janda KD. Heroin vaccine: Using titer, affinity, and antinociception as metrics when examining sex and strain differences. Vaccine. PMID 31176539 DOI: 10.1016/J.Vaccine.2019.05.061 |
0.698 |
|
| 2019 |
Natori Y, Hwang CS, Lin L, Smith LC, Zhou B, Janda KD. A chemically contiguous hapten approach for a heroin-fentanyl vaccine. Beilstein Journal of Organic Chemistry. 15: 1020-1031. PMID 31164940 DOI: 10.3762/Bjoc.15.100 |
0.356 |
|
| 2019 |
Wenthur CJ, Gautam R, Zhou B, Vendruscolo LF, Leggio L, Janda KD. Ghrelin Receptor Influence on Cocaine Reward is Not Directly Dependent on Peripheral Acyl-Ghrelin. Scientific Reports. 9: 1841. PMID 30755699 DOI: 10.1038/S41598-019-38549-Z |
0.772 |
|
| 2019 |
Lavey BJ, Janda KD. Catalytic Antibody Mediated Hydrolysis of Paraoxon. The Journal of Organic Chemistry. 61: 7633-7636. PMID 11667704 DOI: 10.1021/Jo960629D |
0.336 |
|
| 2019 |
Wenthur CJ, Bonakdar R, Janda KD. Investigation of Immunologic Responses Following Chronic Opioid Use to Treat Lower Back Pain The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.Lb8 |
0.66 |
|
| 2018 |
Hwang CS, Ellis B, Zhou B, Janda KD. Heat shock proteins: A dual carrier-adjuvant for an anti-drug vaccine against heroin. Bioorganic & Medicinal Chemistry. PMID 30497790 DOI: 10.1016/J.Bmc.2018.11.027 |
0.379 |
|
| 2018 |
Smith LC, Lin L, Hwang CS, Zhou B, Kubitz DM, Wang H, Janda KD. Lateral Flow Assessment and Unanticipated Toxicity of Kratom. Chemical Research in Toxicology. PMID 30380840 DOI: 10.1021/Acs.Chemrestox.8B00218 |
0.337 |
|
| 2018 |
Shirey R, Globisch D, Eubanks LM, Hixon MS, Janda KD. Non-Invasive Urine Biomarker Lateral Flow Immunoassay for Monitoring Active Onchocerciasis. Acs Infectious Diseases. PMID 30141624 DOI: 10.1021/Acsinfecdis.8B00163 |
0.643 |
|
| 2018 |
Jacob NT, Miranda PO, Shirey RJ, Gautam R, Zhou B, de Orbe Izquierdo ME, Hixon MS, Hart JR, Ueno L, Vogt PK, Janda KD. Synthetic molecules for disruption of the MYC protein-protein interface. Bioorganic & Medicinal Chemistry. PMID 30037753 DOI: 10.1016/J.Bmc.2018.07.019 |
0.599 |
|
| 2018 |
Nguyen JD, Hwang CS, Grant Y, Janda KD, Taffe MA. Prophylactic vaccination protects against the development of oxycodone self-administration. Neuropharmacology. PMID 29936242 DOI: 10.1016/J.Neuropharm.2018.06.026 |
0.326 |
|
| 2018 |
Kimishima A, Olson ME, Natori Y, Janda KD. Efficient Syntheses of Cocaine Vaccines and Their Evaluation. Acs Medicinal Chemistry Letters. 9: 411-416. PMID 29795751 DOI: 10.1021/Acsmedchemlett.8B00051 |
0.799 |
|
| 2018 |
Hwang CS, Smith LC, Natori Y, Ellis B, Zhou B, Janda KD. An efficacious vaccine against heroin contaminated with fentanyl. Acs Chemical Neuroscience. PMID 29558798 DOI: 10.1021/Acschemneuro.8B00079 |
0.332 |
|
| 2018 |
Hwang CS, Bremer PT, Wenthur CJ, Ho SO, Chiang S, Ellis B, Zhou B, Fujii G, Janda KD. Enhancing Efficacy and Stability of an Anti-Heroin Vaccine: Examination of Antinociception, Opioid Binding Profile, and Lethality. Molecular Pharmaceutics. PMID 29420901 DOI: 10.1021/Acs.Molpharmaceut.7B00933 |
0.707 |
|
| 2018 |
Miranda PO, Cubitt B, Jacob NT, Janda KD, Carlos de la Torre J. Mining a Kröhnke Pyridine Library for Anti-Arenavirus Activity. Acs Infectious Diseases. PMID 29405696 DOI: 10.1021/Acsinfecdis.7B00236 |
0.343 |
|
| 2018 |
Ferri GM, Harvey CM, Globisch D, Janda K, Allen KN. Using M. marinum T6PP as a Model for M. tuberculosis Inhibitor Design The Faseb Journal. 32. DOI: 10.1096/Fasebj.2018.32.1_Supplement.674.16 |
0.611 |
|
| 2017 |
Kimishima A, Olson ME, Janda KD. Investigations into the efficacy of multi-component cocaine vaccines. Bioorganic & Medicinal Chemistry Letters. PMID 29317163 DOI: 10.1016/J.Bmcl.2017.12.043 |
0.797 |
|
| 2017 |
Olson ME, Janda KD. Vaccines to combat the opioid crisis: Vaccines that prevent opioids and other substances of abuse from entering the brain could effectively treat addiction and abuse. Embo Reports. PMID 29237715 DOI: 10.15252/Embr.201745322 |
0.322 |
|
| 2017 |
Wenthur CJ, Zhou B, Janda KD. Vaccine-driven pharmacodynamic dissection and mitigation of fenethylline psychoactivity. Nature. PMID 28813419 DOI: 10.1038/Nature23464 |
0.713 |
|
| 2017 |
Wenthur CJ, Cai X, Ellis BA, Janda KD. Augmenting the efficacy of anti-cocaine catalytic antibodies through chimeric hapten design and combinatorial vaccination. Bioorganic & Medicinal Chemistry Letters. PMID 28709828 DOI: 10.1016/J.Bmcl.2017.07.014 |
0.737 |
|
| 2017 |
Jacob NT, Anraku K, Kimishima A, Zhou B, Collins KC, Lockner JW, Ellis BA, Janda KD. A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior. Chemical Communications (Cambridge, England). PMID 28677711 DOI: 10.1039/C7Cc04055E |
0.791 |
|
| 2017 |
Bremer PT, Janda KD. Conjugate Vaccine Immunotherapy for Substance Use Disorder. Pharmacological Reviews. 69: 298-315. PMID 28634286 DOI: 10.1124/Pr.117.013904 |
0.367 |
|
| 2017 |
Globisch D, Eubanks LM, Shirey RJ, Pfarr KM, Wanji S, Debrah AY, Hoerauf A, Janda KD. Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG). Bioorganic & Medicinal Chemistry Letters. PMID 28600214 DOI: 10.1016/J.Bmcl.2017.05.082 |
0.632 |
|
| 2017 |
Bremer PT, Schlosburg JE, Banks ML, Steele FF, Zhou B, Poklis JL, Janda KD. Development of a Clinically-Viable Heroin Vaccine. Journal of the American Chemical Society. PMID 28574716 DOI: 10.1021/Jacs.7B03334 |
0.709 |
|
| 2017 |
Nguyen JD, Bremer PT, Hwang CS, Vandewater SA, Collins KC, Creehan KM, Janda KD, Taffe MA. Effective active vaccination against methamphetamine in female rats. Drug and Alcohol Dependence. 175: 179-186. PMID 28437722 DOI: 10.1016/J.Drugalcdep.2017.03.005 |
0.302 |
|
| 2017 |
Galinato MH, Lockner JW, Fannon-Pavlich MJ, Sobieraj JC, Staples MC, Somkuwar SS, Ghofranian A, Chaing S, Navarro AI, Joea A, Luikart BW, Janda KD, Heyser C, Koob GF, Mandyam CD. A synthetic small-molecule Isoxazole-9 protects against methamphetamine relapse. Molecular Psychiatry. PMID 28348387 DOI: 10.1038/Mp.2017.46 |
0.777 |
|
| 2017 |
Anraku K, Sato S, Jacob NT, Eubanks LM, Ellis BA, Janda KD. The design and synthesis of an α-Gal trisaccharide epitope that provides a highly specific anti-Gal immune response. Organic & Biomolecular Chemistry. PMID 28294277 DOI: 10.1039/C7Ob00448F |
0.376 |
|
| 2017 |
Kimishima A, Wenthur CJ, Zhou B, Janda KD. An Advance in Prescription Opioid Vaccines: Overdose Mortality Reduction and Extraordinary Alteration of Drug Half-Life. Acs Chemical Biology. 12: 36-40. PMID 28103678 DOI: 10.1021/Acschembio.6B00977 |
0.793 |
|
| 2016 |
Bremer PT, Adler M, Phung CH, Singh AK, Janda KD. Newly Designed Quinolinol Inhibitors Mitigate the Effects of Botulinum Neurotoxin A in Enzymatic, Cell-Based and Ex Vivo Assays. Journal of Medicinal Chemistry. PMID 27966961 DOI: 10.1021/Acs.Jmedchem.6B01393 |
0.301 |
|
| 2016 |
Gooyit MD, Miranda PO, Wenthur CJ, Ducime A, Janda KD. Influencing antibody-mediated attenuation of methamphetamine CNS distribution through vaccine linker design. Acs Chemical Neuroscience. PMID 27958709 DOI: 10.1021/Acschemneuro.6B00389 |
0.806 |
|
| 2016 |
Nguyen JD, Bremer PT, Ducime A, Creehan KM, Kisby BR, Taffe MA, Janda KD. Active vaccination attenuates the psychostimulant effects of α-PVP and MDPV in rats. Neuropharmacology. PMID 27956054 DOI: 10.1016/J.Neuropharm.2016.12.005 |
0.315 |
|
| 2016 |
Kimishima A, Wenthur CJ, Eubanks LM, Sato S, Janda KD. Cocaine Vaccine Development: Evaluation of Carrier and Adjuvant Combinations that Activate Multiple Toll-like Receptors. Molecular Pharmaceutics. PMID 27717287 DOI: 10.1021/Acs.Molpharmaceut.6B00682 |
0.795 |
|
| 2016 |
Evans SM, Foltin RW, Hicks MJ, Rosenberg JB, De BP, Janda KD, Kaminsky SM, Crystal RG. Efficacy of an adenovirus-based anti-cocaine vaccine to reduce cocaine self-administration and Reacqusition using a choice procedure in rhesus macaques. Pharmacology, Biochemistry, and Behavior. PMID 27697554 DOI: 10.1016/J.Pbb.2016.09.008 |
0.323 |
|
| 2016 |
Gooyit M, Janda KD. Reprofiled anthelmintics abate hypervirulent stationary-phase Clostridium difficile. Scientific Reports. 6: 33642. PMID 27633064 DOI: 10.1038/Srep33642 |
0.719 |
|
| 2016 |
Gooyit MD, Janda KD. Modulation of the Surface-Layer Protein of Clostridium difficile through Cwp84 Inhibition. Acs Infectious Diseases. 2: 465-70. PMID 27626098 DOI: 10.1021/Acsinfecdis.6B00061 |
0.721 |
|
| 2016 |
Zhou B, Eubanks LM, Jacob NT, Ellis B, Roberts AJ, Janda KD. Studies towards the improvement of an anti-cocaine monoclonal antibody for treatment of acute overdose. Bioorganic & Medicinal Chemistry Letters. PMID 27599743 DOI: 10.1016/J.Bmcl.2016.08.081 |
0.347 |
|
| 2016 |
Collins KC, Schlosburg JE, Bremer PT, Janda KD. Methamphetamine Vaccines: Improvement through Hapten Design. Journal of Medicinal Chemistry. PMID 27054372 DOI: 10.1021/Acs.Jmedchem.6B00084 |
0.693 |
|
| 2016 |
Jacob NT, Lockner JW, Schlosburg JE, Ellis BA, Eubanks LM, Janda KD. Investigations of Enantiopure Nicotine Haptens using an Adjuvanting Carrier in Anti-Nicotine Vaccine Development. Journal of Medicinal Chemistry. PMID 26918428 DOI: 10.1021/Acs.Jmedchem.5B01676 |
0.795 |
|
| 2016 |
Harris TL, Wenthur CJ, Diego-Taboada A, Mackenzie G, Corbitt TS, Janda KD. Lycopodium clavatum exine microcapsules enable safe oral delivery of 3,4-diaminopyridine for treatment of botulinum neurotoxin A intoxication. Chemical Communications (Cambridge, England). PMID 26906286 DOI: 10.1039/C6Cc00615A |
0.669 |
|
| 2016 |
Tsuchikama K, Gooyit M, Harris TL, Zhu J, Globisch D, Kaufmann GF, Janda KD. Glycation Reactivity of a Quorum-Sensing Signaling Molecule. Angewandte Chemie (International Ed. in English). PMID 26890076 DOI: 10.1002/Anie.201511911 |
0.776 |
|
| 2016 |
Bremer PT, Kimishima A, Schlosburg JE, Zhou B, Collins KC, Janda KD. Combatting Synthetic Designer Opioids: A Conjugate Vaccine Ablates Lethal Doses of Fentanyl Class Drugs. Angewandte Chemie (International Ed. in English). PMID 26879590 DOI: 10.1002/Anie.201511654 |
0.798 |
|
| 2016 |
Hart JR, Weinberg MS, Morris KV, Roberts TC, Janda KD, Garner AL, Vogt PK. MINCR is not a MYC-induced lncRNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 26811502 DOI: 10.1073/Pnas.1519903113 |
0.55 |
|
| 2015 |
Gooyit M, Harris TL, Tricoche N, Javor S, Lustigman S, Janda KD. Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping. Acs Infectious Diseases. 1: 198-202. PMID 27622649 DOI: 10.1021/Acsinfecdis.5B00017 |
0.726 |
|
| 2015 |
Globisch D, Specht S, Pfarr KM, Eubanks LM, Hoerauf A, Janda KD. Litomosoides sigmodontis: A jird urine metabolome study. Bioorganic & Medicinal Chemistry Letters. 25: 5804-7. PMID 26573416 DOI: 10.1016/J.Bmcl.2015.10.037 |
0.623 |
|
| 2015 |
Xue S, Schlosburg JE, Janda KD. A New Strategy for Smoking Cessation: Characterization of a Bacterial Enzyme for the Degradation of Nicotine. Journal of the American Chemical Society. 137: 10136-9. PMID 26237398 DOI: 10.1021/Jacs.5B06605 |
0.648 |
|
| 2015 |
Miller ML, Aarde SM, Moreno AY, Creehan KM, Janda KD, Taffe MA. Effects of active anti-methamphetamine vaccination on intravenous self-administration in rats. Drug and Alcohol Dependence. PMID 26118833 DOI: 10.1016/J.Drugalcdep.2015.06.014 |
0.769 |
|
| 2015 |
Zhu J, Cai X, Harris TL, Gooyit M, Wood M, Lardy M, Janda KD. Disarming Pseudomonas aeruginosa virulence factor LasB by leveraging a Caenorhabditis elegans infection model. Chemistry & Biology. 22: 483-91. PMID 25892201 DOI: 10.1016/J.Chembiol.2015.03.012 |
0.728 |
|
| 2015 |
Gooyit M, Tricoche N, Javor S, Lustigman S, Janda KD. Exploiting the Polypharmacology of ß-Carbolines to Disrupt O. volvulus Molting. Acs Medicinal Chemistry Letters. 6: 339-43. PMID 25815157 DOI: 10.1021/Ml500516R |
0.724 |
|
| 2015 |
Lockner JW, Eubanks LM, Choi JL, Lively JM, Schlosburg JE, Collins KC, Globisch D, Rosenfeld-Gunn RJ, Wilson IA, Janda KD. Flagellin as carrier and adjuvant in cocaine vaccine development. Molecular Pharmaceutics. 12: 653-62. PMID 25531528 DOI: 10.1021/Mp500520R |
0.801 |
|
| 2015 |
Lockner JW, Lively JM, Collins KC, Vendruscolo JC, Azar MR, Janda KD. A conjugate vaccine using enantiopure hapten imparts superior nicotine-binding capacity. Journal of Medicinal Chemistry. 58: 1005-11. PMID 25493909 DOI: 10.1021/Jm501625J |
0.773 |
|
| 2015 |
Pippione AC, Dosio F, Ducime A, Federico A, Martina K, Sainas S, Frølund B, Gooyit M, Janda KD, Boschi D, Lolli ML. Substituted 4-hydroxy-1,2,3-triazoles: synthesis, characterization and first drug design applications through bioisosteric modulation and scaffold hopping approaches Medchemcomm. 6: 1285-1292. DOI: 10.1039/C5Md00182J |
0.737 |
|
| 2015 |
Gooyit M, Harris TL, Tricoche N, Javor S, Lustigman S, Janda KD. Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping Acs Infectious Diseases. 1: 198-202. DOI: 10.1021/acsinfecdis.5b00017 |
0.709 |
|
| 2015 |
Cai X, Globisch D, Thompson P, Lin J, Toader D, Dimasi N, Gao C, Janda KD. Corrigendum to "A chemoenzymatic approach toward the preparation of site-specific antibody-drug conjugates" [Tetrahedron Lett. 56 (2015) 3172-3175] Tetrahedron Letters. DOI: 10.1016/J.Tetlet.2015.06.088 |
0.73 |
|
| 2015 |
Cai X, Janda KD. A chemoenzymatic approach toward the preparation of site-specific antibody-drug conjugates Tetrahedron Letters. 56: 3172-3175. DOI: 10.1016/J.Tetlet.2014.12.025 |
0.353 |
|
| 2014 |
Eubanks LM, Ellis BA, Cai X, Schlosburg JE, Janda KD. A human recombinant monoclonal antibody to cocaine: Preparation, characterization and behavioral studies. Bioorganic & Medicinal Chemistry Letters. 24: 4664-6. PMID 25205191 DOI: 10.1016/J.Bmcl.2014.08.035 |
0.701 |
|
| 2014 |
Hart JR, Garner AL, Yu J, Ito Y, Sun M, Ueno L, Rhee JK, Baksh MM, Stefan E, Hartl M, Bister K, Vogt PK, Janda KD. Inhibitor of MYC identified in a Kröhnke pyridine library. Proceedings of the National Academy of Sciences of the United States of America. 111: 12556-61. PMID 25114221 DOI: 10.1073/Pnas.1319488111 |
0.595 |
|
| 2014 |
Harris TL, Lowery CA, Hixon MS, Janda KD. A platform stratifying a sequestering agent and a pharmacological antagonist as a means to negate botulinum neurotoxicity. Acs Chemical Neuroscience. 5: 632-6. PMID 25000171 DOI: 10.1021/Cn500135H |
0.302 |
|
| 2014 |
Bremer PT, Hixon MS, Janda KD. Benzoquinones as inhibitors of botulinum neurotoxin serotype A. Bioorganic & Medicinal Chemistry. 22: 3971-81. PMID 24984937 DOI: 10.1016/J.Bmc.2014.06.004 |
0.301 |
|
| 2014 |
Gooyit M, Tricoche N, Lustigman S, Janda KD. Dual protonophore-chitinase inhibitors dramatically affect O. volvulus molting. Journal of Medicinal Chemistry. 57: 5792-9. PMID 24918716 DOI: 10.1021/Jm5006435 |
0.732 |
|
| 2014 |
Jacob NT, Lockner JW, Kravchenko VV, Janda KD. Pharmacophore reassignment for induction of the immunosurveillance cytokine TRAIL. Angewandte Chemie (International Ed. in English). 53: 6628-31. PMID 24838721 DOI: 10.1002/Anie.201402133 |
0.748 |
|
| 2014 |
Hicks MJ, Kaminsky SM, De BP, Rosenberg JB, Evans SM, Foltin RW, Andrenyak DM, Moody DE, Koob GF, Janda KD, Ricart Arbona RJ, Lepherd ML, Crystal RG. Fate of systemically administered cocaine in nonhuman primates treated with the dAd5GNE anticocaine vaccine. Human Gene Therapy. Clinical Development. 25: 40-9. PMID 24649839 DOI: 10.1089/Humc.2013.231 |
0.477 |
|
| 2014 |
Collins KC, Schlosburg JE, Lockner JW, Bremer PT, Ellis BA, Janda KD. Lipid tucaresol as an adjuvant for methamphetamine vaccine development. Chemical Communications (Cambridge, England). 50: 4079-81. PMID 24615284 DOI: 10.1039/C4Cc00682H |
0.782 |
|
| 2014 |
Hicks MJ, Kaminsky SM, De BP, Rosenberg JB, Evans SM, Foltin RW, Andrenyak DM, Moody DE, Koob GF, Janda KD, Ricart Arbona RJ, Lepherd M, Crystal RG. Fate of Systemically Administered Cocaine in Nonhuman Primates Treated with the dAd5GNE Anti-cocaine Vaccine. Human Gene Therapy. Clinical Development. PMID 24548017 DOI: 10.1089/hum.2013.231 |
0.398 |
|
| 2014 |
Collins KC, Janda KD. Investigating hapten clustering as a strategy to enhance vaccines against drugs of abuse. Bioconjugate Chemistry. 25: 593-600. PMID 24521489 DOI: 10.1021/Bc500016K |
0.35 |
|
| 2014 |
Bremer PT, Schlosburg JE, Lively JM, Janda KD. Injection route and TLR9 agonist addition significantly impact heroin vaccine efficacy. Molecular Pharmaceutics. 11: 1075-80. PMID 24517171 DOI: 10.1021/Mp400631W |
0.7 |
|
| 2014 |
Miller ML, Moreno A, Aarde S, Creehan K, Janda K, Taffe MA. Active vaccination inhibits the acquisition of methamphetamine self-administration in rats Drug and Alcohol Dependence. 140: e151. DOI: 10.1016/J.Drugalcdep.2014.02.426 |
0.766 |
|
| 2013 |
Cai X, Whitfield T, Moreno AY, Grant Y, Hixon MS, Koob GF, Janda KD. Probing the effects of hapten stability on cocaine vaccine immunogenicity. Molecular Pharmaceutics. 10: 4176-84. PMID 23927436 DOI: 10.1021/Mp400214W |
0.803 |
|
| 2013 |
Lowery CA, Matamouros S, Niessen S, Zhu J, Scolnick J, Lively JM, Cravatt BF, Miller SI, Kaufmann GF, Janda KD. A chemical biology approach to interrogate quorum-sensing regulated behaviors at the molecular and cellular level. Chemistry & Biology. 20: 903-11. PMID 23890008 DOI: 10.1016/J.Chembiol.2013.05.009 |
0.446 |
|
| 2013 |
Garner AL, Kim SK, Zhu J, Struss AK, Watkins R, Feske BD, Kaufmann GF, Janda KD. Retraction: Stereochemical insignificance discovered in Acinetobacter baumannii quorum sensing (PLoS ONE) Plos One. 8. PMID 23853689 DOI: 10.1371/annotation/8f2ddf91-3499-4627-9a91-449b78465f9d |
0.518 |
|
| 2013 |
Garner AL, Fullagar JL, Day JA, Cohen SM, Janda KD. Development of a high-throughput screen and its use in the discovery of Streptococcus pneumoniae immunoglobulin A1 protease inhibitors. Journal of the American Chemical Society. 135: 10014-7. PMID 23808771 DOI: 10.1021/Ja404180X |
0.605 |
|
| 2013 |
Garner AL, Kim SK, Zhu J, Struss AK, Watkins R, Feske BD, Kaufmann GF, Janda KD. Retraction: Stereochemical Insignificance Discovered in Acinetobacter baumannii Quorum Sensing Plos One. 8. PMID 23690906 DOI: 10.1371/Annotation/1345F9B0-016E-4123-9E72-6Ccc4Fa17Ba2 |
0.589 |
|
| 2013 |
Zhu J, Hixon MS, Globisch D, Kaufmann GF, Janda KD. Mechanistic insights into the LsrK kinase required for autoinducer-2 quorum sensing activation. Journal of the American Chemical Society. 135: 7827-30. PMID 23672516 DOI: 10.1021/Ja4024989 |
0.641 |
|
| 2013 |
Maoz A, Hicks MJ, Vallabhjosula S, Synan M, Kothari PJ, Dyke JP, Ballon DJ, Kaminsky SM, De BP, Rosenberg JB, Martinez D, Koob GF, Janda KD, Crystal RG. Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2170-8. PMID 23660705 DOI: 10.1038/Npp.2013.114 |
0.46 |
|
| 2013 |
Schlosburg JE, Vendruscolo LF, Bremer PT, Lockner JW, Wade CL, Nunes AA, Stowe GN, Edwards S, Janda KD, Koob GF. Dynamic vaccine blocks relapse to compulsive intake of heroin. Proceedings of the National Academy of Sciences of the United States of America. 110: 9036-41. PMID 23650354 DOI: 10.1073/Pnas.1219159110 |
0.803 |
|
| 2013 |
Cai X, Whitfield T, Hixon MS, Grant Y, Koob GF, Janda KD. Probing active cocaine vaccination performance through catalytic and noncatalytic hapten design. Journal of Medicinal Chemistry. 56: 3701-9. PMID 23627877 DOI: 10.1021/Jm400228W |
0.498 |
|
| 2013 |
Matyas GR, Mayorov AV, Rice KC, Jacobson AE, Cheng K, Iyer MR, Li F, Beck Z, Janda KD, Alving CR. Liposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs. Vaccine. 31: 2804-10. PMID 23624097 DOI: 10.1016/J.Vaccine.2013.04.027 |
0.695 |
|
| 2013 |
Rosenberg JB, De BP, Hicks MJ, Janda KD, Kaminsky SM, Worgall S, Crystal RG. Suppression of nicotine-induced pathophysiology by an adenovirus hexon-based antinicotine vaccine. Human Gene Therapy. 24: 595-603. PMID 23611296 DOI: 10.1089/Hum.2012.245 |
0.322 |
|
| 2013 |
Kravchenko V, Garner AL, Mathison J, Seit-Nebi A, Yu J, Gileva IP, Ulevitch R, Janda KD. Facilitating cytokine-mediated cancer cell death by proteobacterial N-acylhomoserine lactones. Acs Chemical Biology. 8: 1117-20. PMID 23517377 DOI: 10.1021/Cb4000184 |
0.571 |
|
| 2013 |
Fullagar JL, Garner AL, Struss AK, Day JA, Martin DP, Yu J, Cai X, Janda KD, Cohen SM. Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: tropolones as inhibitors of P. aeruginosa elastase. Chemical Communications (Cambridge, England). 49: 3197-9. PMID 23482955 DOI: 10.1039/C3Cc41191E |
0.6 |
|
| 2013 |
Globisch D, Moreno AY, Hixon MS, Nunes AA, Denery JR, Specht S, Hoerauf A, Janda KD. Onchocerca volvulus-neurotransmitter tyramine is a biomarker for river blindness. Proceedings of the National Academy of Sciences of the United States of America. 110: 4218-23. PMID 23440222 DOI: 10.1073/Pnas.1221969110 |
0.762 |
|
| 2013 |
Cai X, Tsuchikama K, Janda KD. Modulating cocaine vaccine potency through hapten fluorination. Journal of the American Chemical Society. 135: 2971-4. PMID 23398531 DOI: 10.1021/Ja400356G |
0.347 |
|
| 2013 |
Struss AK, Nunes A, Waalen J, Lowery CA, Pullanikat P, Denery JR, Conrad DJ, Kaufmann GF, Janda KD. Toward implementation of quorum sensing autoinducers as biomarkers for infectious disease states. Analytical Chemistry. 85: 3355-62. PMID 23391272 DOI: 10.1021/Ac400032A |
0.764 |
|
| 2013 |
Šilhár P, Silvaggi NR, Pellett S, Čapková K, Johnson EA, Allen KN, Janda KD. Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: synthesis, crystallography, modeling, kinetic and cellular based studies. Bioorganic & Medicinal Chemistry. 21: 1344-8. PMID 23340139 DOI: 10.1016/J.Bmc.2012.12.001 |
0.302 |
|
| 2013 |
Garner AL, Yu J, Struss AK, Kaufmann GF, Kravchenko VV, Janda KD. Immunomodulation and the quorum sensing molecule 3-oxo-C12-homoserine lactone: the importance of chemical scaffolding for probe development. Chemical Communications (Cambridge, England). 49: 1515-7. PMID 23328974 DOI: 10.1039/C3Cc38851D |
0.593 |
|
| 2013 |
Lockner JW, Ho SO, McCague KC, Chiang SM, Do TQ, Fujii G, Janda KD. Enhancing nicotine vaccine immunogenicity with liposomes. Bioorganic & Medicinal Chemistry Letters. 23: 975-8. PMID 23313243 DOI: 10.1016/J.Bmcl.2012.12.048 |
0.773 |
|
| 2013 |
De BP, Pagovich OE, Hicks MJ, Rosenberg JB, Moreno AY, Janda KD, Koob GF, Worgall S, Kaminsky SM, Sondhi D, Crystal RG. Disrupted adenovirus-based vaccines against small addictive molecules circumvent anti-adenovirus immunity. Human Gene Therapy. 24: 58-66. PMID 23140508 DOI: 10.1089/Hum.2012.163 |
0.8 |
|
| 2013 |
Miller ML, Moreno AY, Aarde SM, Creehan KM, Vandewater SA, Vaillancourt BD, Wright MJ, Janda KD, Taffe MA. A methamphetamine vaccine attenuates methamphetamine-induced disruptions in thermoregulation and activity in rats. Biological Psychiatry. 73: 721-8. PMID 23098894 DOI: 10.1016/J.Biopsych.2012.09.010 |
0.781 |
|
| 2012 |
Garner AL, Struss AK, Fullagar JL, Agrawal A, Moreno AY, Cohen SM, Janda KD. 3-Hydroxy-1-alkyl-2-methylpyridine-4(1H)-thiones: Inhibition of the Pseudomonas aeruginosa Virulence Factor LasB. Acs Medicinal Chemistry Letters. 3: 668-672. PMID 23181168 DOI: 10.1021/Ml300128F |
0.771 |
|
| 2012 |
Bremer PT, Janda KD. Investigating the effects of a hydrolytically stable hapten and a Th1 adjuvant on heroin vaccine performance. Journal of Medicinal Chemistry. 55: 10776-80. PMID 23134263 DOI: 10.1021/Jm301262Z |
0.31 |
|
| 2012 |
Moreno AY, Azar MR, Koob GF, Janda KD. Probing the protective effects of a conformationally constrained nicotine vaccine. Vaccine. 30: 6665-70. PMID 22963803 DOI: 10.1016/J.Vaccine.2012.08.064 |
0.802 |
|
| 2012 |
Garner AL, Kim SK, Zhu J, Struss AK, Watkins R, Feske BD, Kaufmann GF, Janda KD. Stereochemical insignificance discovered in Acinetobacter baumannii quorum sensing. Plos One. 7: e37102. PMID 22629354 DOI: 10.1371/Journal.Pone.0037102 |
0.599 |
|
| 2012 |
Rosenberg JB, Hicks MJ, De BP, Pagovich O, Frenk E, Janda KD, Wee S, Koob GF, Hackett NR, Kaminsky SM, Worgall S, Tignor N, Mezey JG, Crystal RG. AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior. Human Gene Therapy. 23: 451-9. PMID 22486244 DOI: 10.1089/Hum.2011.178 |
0.479 |
|
| 2012 |
Treweek JB, Janda KD. An antidote for acute cocaine toxicity. Molecular Pharmaceutics. 9: 969-78. PMID 22380623 DOI: 10.1021/Mp200588V |
0.358 |
|
| 2012 |
Globisch D, Lowery CA, McCague KC, Janda KD. Uncharacterized 4,5-dihydroxy-2,3-pentanedione (DPD) molecules revealed through NMR spectroscopy: implications for a greater signaling diversity in bacterial species. Angewandte Chemie (International Ed. in English). 51: 4204-8. PMID 22378693 DOI: 10.1002/Anie.201109149 |
0.631 |
|
| 2012 |
Janda KD, Treweek JB. Vaccines targeting drugs of abuse: is the glass half-empty or half-full? Nature Reviews. Immunology. 12: 67-72. PMID 22173478 DOI: 10.1038/Nri3130 |
0.323 |
|
| 2012 |
Zakhari JS, Zorrilla EP, Zhou B, Mayorov AV, Janda KD. Oligoclonal antibody targeting ghrelin increases energy expenditure and reduces food intake in fasted mice. Molecular Pharmaceutics. 9: 281-9. PMID 22149064 DOI: 10.1021/Mp200376C |
0.688 |
|
| 2012 |
Wee S, Hicks MJ, De BP, Rosenberg JB, Moreno AY, Kaminsky SM, Janda KD, Crystal RG, Koob GF. Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1083-91. PMID 21918504 DOI: 10.1038/Npp.2011.200 |
0.793 |
|
| 2012 |
Globisch D, Lowery CA, McCague KC, Janda KD. Inside Back Cover: Uncharacterized 4,5-Dihydroxy-2,3-Pentanedione (DPD) Molecules Revealed Through NMR Spectroscopy: Implications for a Greater Signaling Diversity in Bacterial Species (Angew. Chem. Int. Ed. 17/2012) Angewandte Chemie International Edition. 51: 4239-4239. DOI: 10.1002/Anie.201201407 |
0.614 |
|
| 2012 |
Globisch D, Lowery CA, McCague KC, Janda KD. Innenrücktitelbild: Uncharacterized 4,5-Dihydroxy-2,3-Pentanedione (DPD) Molecules Revealed Through NMR Spectroscopy: Implications for a Greater Signaling Diversity in Bacterial Species (Angew. Chem. 17/2012) Angewandte Chemie. 124: 4313-4313. DOI: 10.1002/Ange.201201407 |
0.614 |
|
| 2011 |
Koob G, Hicks MJ, Wee S, Rosenberg JB, De BP, Kaminsky SM, Moreno A, Janda KD, Crystal RG. Anti-cocaine vaccine based on coupling a cocaine analog to a disrupted adenovirus. Cns & Neurological Disorders Drug Targets. 10: 899-904. PMID 22229312 DOI: 10.2174/187152711799219334 |
0.79 |
|
| 2011 |
Stowe GN, Schlosburg JE, Vendruscolo LF, Edwards S, Misra KK, Schulteis G, Zakhari JS, Koob GF, Janda KD. Developing a vaccine against multiple psychoactive targets: a case study of heroin. Cns & Neurological Disorders Drug Targets. 10: 865-75. PMID 22229311 DOI: 10.2174/187152711799219316 |
0.733 |
|
| 2011 |
Li Z, Garner AL, Gloeckner C, Janda KD, Carlow CK. Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy. Plos Neglected Tropical Diseases. 5: e1411. PMID 22140592 DOI: 10.1371/Journal.Pntd.0001411 |
0.615 |
|
| 2011 |
Moreno AY, Janda KD. Current challenges for the creation of effective vaccines against drugs of abuse. Expert Review of Vaccines. 10: 1637-9. PMID 22085165 DOI: 10.1586/Erv.11.145 |
0.768 |
|
| 2011 |
Zakhari JS, Kinoyama I, Hixon MS, Di Mola A, Globisch D, Janda KD. Formulating a new basis for the treatment against botulinum neurotoxin intoxication: 3,4-Diaminopyridine prodrug design and characterization. Bioorganic & Medicinal Chemistry. 19: 6203-9. PMID 21975066 DOI: 10.1016/J.Bmc.2011.09.019 |
0.646 |
|
| 2011 |
Eubanks LM, Stowe GN, De Lamo Marin S, Mayorov AV, Hixon MS, Janda KD. Identification of α2 macroglobulin as a major serum ghrelin esterase. Angewandte Chemie (International Ed. in English). 50: 10699-702. PMID 21928452 DOI: 10.1002/Anie.201104512 |
0.646 |
|
| 2011 |
Garner AL, Park J, Zakhari JS, Lowery CA, Struss AK, Sawada D, Kaufmann GF, Janda KD. A multivalent probe for AI-2 quorum-sensing receptors. Journal of the American Chemical Society. 133: 15934-7. PMID 21913711 DOI: 10.1021/Ja207556D |
0.577 |
|
| 2011 |
Stowe GN, Vendruscolo LF, Edwards S, Schlosburg JE, Misra KK, Schulteis G, Mayorov AV, Zakhari JS, Koob GF, Janda KD. A vaccine strategy that induces protective immunity against heroin. Journal of Medicinal Chemistry. 54: 5195-204. PMID 21692508 DOI: 10.1021/Jm200461M |
0.809 |
|
| 2011 |
Garner AL, Janda KD. A small molecule antagonist of ghrelin O-acyltransferase (GOAT). Chemical Communications (Cambridge, England). 47: 7512-4. PMID 21594284 DOI: 10.1039/C1Cc11817J |
0.602 |
|
| 2011 |
Garner AL, Gloeckner C, Tricoche N, Zakhari JS, Samje M, Cho-Ngwa F, Lustigman S, Janda KD. Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus. Journal of Medicinal Chemistry. 54: 3963-72. PMID 21534605 DOI: 10.1021/Jm200364N |
0.614 |
|
| 2011 |
Uckun FM, Qazi S, Ozer Z, Garner AL, Pitt J, Ma H, Janda KD. Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network. British Journal of Haematology. 153: 741-52. PMID 21517817 DOI: 10.1111/J.1365-2141.2011.08671.X |
0.599 |
|
| 2011 |
Moreno AY, Mayorov AV, Janda KD. Impact of distinct chemical structures for the development of a methamphetamine vaccine. Journal of the American Chemical Society. 133: 6587-95. PMID 21473576 DOI: 10.1021/Ja108807J |
0.813 |
|
| 2011 |
Kirchdoerfer RN, Garner AL, Flack CE, Mee JM, Horswill AR, Janda KD, Kaufmann GF, Wilson IA. Structural basis for ligand recognition and discrimination of a quorum-quenching antibody. The Journal of Biological Chemistry. 286: 17351-8. PMID 21454495 DOI: 10.1074/Jbc.M111.231258 |
0.626 |
|
| 2011 |
Šilhár P, Alakurtti S, ?apková K, Xiaochuan F, Shoemaker CB, Yli-Kauhaluoma J, Janda KD. Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease. Bioorganic & Medicinal Chemistry Letters. 21: 2229-31. PMID 21421315 DOI: 10.1016/J.Bmcl.2011.02.115 |
0.544 |
|
| 2011 |
Treweek JB, Roberts AJ, Janda KD. Immunopharmacotherapeutic manifolds and modulation of cocaine overdose. Pharmacology, Biochemistry, and Behavior. 98: 474-84. PMID 21356233 DOI: 10.1016/J.Pbb.2011.02.020 |
0.34 |
|
| 2011 |
Garner AL, Janda KD. Protein-protein interactions and cancer: targeting the central dogma. Current Topics in Medicinal Chemistry. 11: 258-80. PMID 21320057 DOI: 10.2174/156802611794072614 |
0.581 |
|
| 2011 |
Garner AL, Janda KD. Shedding light on the ghrelin/GOAT metabolism saga. Chembiochem : a European Journal of Chemical Biology. 12: 523-5. PMID 21254317 DOI: 10.1002/Cbic.201000777 |
0.571 |
|
| 2011 |
Hicks MJ, De BP, Rosenberg JB, Davidson JT, Moreno AY, Janda KD, Wee S, Koob GF, Hackett NR, Kaminsky SM, Worgall S, Toth M, Mezey JG, Crystal RG. Cocaine analog coupled to disrupted adenovirus: a vaccine strategy to evoke high-titer immunity against addictive drugs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 612-9. PMID 21206484 DOI: 10.1038/Mt.2010.280 |
0.805 |
|
| 2011 |
Garner AL, Yu J, Struss AK, Lowery CA, Zhu J, Kim SK, Park J, Mayorov AV, Kaufmann GF, Kravchenko VV, Janda KD. Synthesis of 'clickable' acylhomoserine lactone quorum sensing probes: unanticipated effects on mammalian cell activation. Bioorganic & Medicinal Chemistry Letters. 21: 2702-5. PMID 21190852 DOI: 10.1016/J.Bmcl.2010.11.122 |
0.751 |
|
| 2011 |
Kaufmann GF, Park J, Mayorov AV, Kubitz DM, Janda KD. Generation of quorum quenching antibodies. Methods in Molecular Biology (Clifton, N.J.). 692: 299-311. PMID 21031321 DOI: 10.1007/978-1-60761-971-0_22 |
0.679 |
|
| 2011 |
Uckun FM, Qazi S, Garner A, Ma H, Ozer Z, Pitt J, Janda K. Abstract LB-365: Unfolded protein response regulator BIP/HSPA5 as a chemoresistance biomarker and molecular target in acute lymphoblastic leukemia Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-365 |
0.598 |
|
| 2010 |
Eubanks LM, Silhár P, Salzameda NT, Zakhari JS, Xiaochuan F, Barbieri JT, Shoemaker CB, Hixon MS, Janda KD. Identification of a Natural Product Antagonist against the Botulinum Neurotoxin Light Chain Protease. Acs Medicinal Chemistry Letters. 1: 268-272. PMID 20959871 DOI: 10.1021/Ml100074S |
0.319 |
|
| 2010 |
Denery JR, Nunes AA, Hixon MS, Dickerson TJ, Janda KD. Metabolomics-based discovery of diagnostic biomarkers for onchocerciasis. Plos Neglected Tropical Diseases. 4. PMID 20957145 DOI: 10.1371/Journal.Pntd.0000834 |
0.766 |
|
| 2010 |
Mayorov AV, Willis B, Di Mola A, Adler D, Borgia J, Jackson O, Wang J, Luo Y, Tang L, Knapp RJ, Natarajan C, Goodnough MC, Zilberberg N, Simpson LL, Janda KD. Symptomatic relief of botulinum neurotoxin/a intoxication with aminopyridines: a new twist on an old molecule. Acs Chemical Biology. 5: 1183-91. PMID 20936877 DOI: 10.1021/Cb1002366 |
0.654 |
|
| 2010 |
Garner AL, Janda KD. cat-ELCCA: a robust method to monitor the fatty acid acyltransferase activity of ghrelin O-acyltransferase (GOAT). Angewandte Chemie (International Ed. in English). 49: 9630-4. PMID 20845345 DOI: 10.1002/Anie.201003387 |
0.592 |
|
| 2010 |
Staflin K, Krueger JS, Hachmann J, Forsyth JS, Lorger M, Steiniger SC, Mee J, Pop C, Salvesen GS, Janda KD, Felding-Habermann B. Targeting activated integrin alphavbeta3 with patient-derived antibodies impacts late-stage multiorgan metastasis. Clinical & Experimental Metastasis. 27: 217-31. PMID 20225083 DOI: 10.1007/S10585-010-9320-5 |
0.336 |
|
| 2010 |
Gloeckner C, Garner AL, Mersha F, Oksov Y, Tricoche N, Eubanks LM, Lustigman S, Kaufmann GF, Janda KD. Repositioning of an existing drug for the neglected tropical disease Onchocerciasis. Proceedings of the National Academy of Sciences of the United States of America. 107: 3424-9. PMID 20142509 DOI: 10.1073/Pnas.0915125107 |
0.617 |
|
| 2010 |
Moreno AY, Azar MR, Warren NA, Dickerson TJ, Koob GF, Janda KD. A critical evaluation of a nicotine vaccine within a self-administration behavioral model. Molecular Pharmaceutics. 7: 431-41. PMID 20104903 DOI: 10.1021/Mp900213U |
0.792 |
|
| 2010 |
Nakai Y, Pellett S, Tepp WH, Johnson EA, Janda KD. Toosendanin: synthesis of the AB-ring and investigations of its anti-botulinum properties (Part II). Bioorganic & Medicinal Chemistry. 18: 1280-7. PMID 20044261 DOI: 10.1016/J.Bmc.2009.12.030 |
0.302 |
|
| 2010 |
Fukuchi K, Steiniger SC, Deryugina E, Liu Y, Lowery CA, Gloeckner C, Zhou B, Kaufmann GF, Quigley JP, Janda KD. Inhibition of tumor metastasis: functional immune modulation of the CUB domain containing protein 1. Molecular Pharmaceutics. 7: 245-53. PMID 19916495 DOI: 10.1021/Mp900236T |
0.315 |
|
| 2010 |
Han H, Yoon J, Janda KD. ChemInform Abstract: Azatides as Peptidomimetics. Solution and Liquid Phase Syntheses Cheminform. 31: no-no. DOI: 10.1002/CHIN.200030276 |
0.327 |
|
| 2010 |
Yoon J, Han H, Janda KD. ChemInform Abstract: Solution and Soluble Polymer Syntheses of Azatides and Aza Peptides Cheminform. 31: no-no. DOI: 10.1002/CHIN.200015248 |
0.344 |
|
| 2010 |
Taylor MJ, Yli-Kauhaluoma JT, Ashley JA, Wirsching P, Lerner RA, Janda KD. ChemInform Abstract: The α-Ketoamide Group: A New Motif for the Elicitation of Catalytic Antibodies for Acyl-Transfer Reactions. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199938222 |
0.494 |
|
| 2010 |
Taylor MJ, Hoffman TZ, Yli-Kauhaluoma JT, Lerner RA, Janda KD. ChemInform Abstract: A Light-Activated Antibody Catalyst. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199917044 |
0.482 |
|
| 2010 |
Yoon J, Cho C, Han H, Janda KD. ChemInform Abstract: Solution and Soluble Polymer Syntheses of 3-Aminoimidazoline-2,4-diones. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199913153 |
0.334 |
|
| 2010 |
YLI-KAUHALUOMA JT, HARWIG CW, WENTWORTH PJ, JANDA KD. ChemInform Abstract: Unexpected 1,3-Oxazolidine Formation in the Attempted Oxidation of N-Aryl-N-methyl Substituted β-Amino Alcohols Using Pyridinium Dichromate. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199829101 |
0.43 |
|
| 2010 |
LI T, LERNER RA, JANDA KD. ChemInform Abstract: Antibody-Catalyzed Cationic Reactions: Rerouting of Chemical Transformations via Antibody Catalysis Cheminform. 28: no-no. DOI: 10.1002/chin.199727296 |
0.444 |
|
| 2010 |
YLI-KAUHALUOMA JT, JANDA KD. ChemInform Abstract: An Expedient Synthesis of Isopropyl Anisoles and Veratroles. Cheminform. 25: no-no. DOI: 10.1002/CHIN.199446109 |
0.444 |
|
| 2010 |
REYMOND J, JANDA KD, LERNER RA. ChemInform Abstract: Highly Enantioselective Protonation Catalyzed by an Antibody. Cheminform. 23: no-no. DOI: 10.1002/chin.199227073 |
0.437 |
|
| 2010 |
REYMOND J, JANDA KD, LERNER RA. ChemInform Abstract: Antibody Catalysis of Glycosidic Bond Hydrolysis. Cheminform. 23: no-no. DOI: 10.1002/chin.199210071 |
0.416 |
|
| 2010 |
JANDA KD, ASHLEY JA, JONES TM, MCLEOD DA, SCHLOEDER DM, WEINHOUSE MI, LERNER RA, GIBBS RA, BENKOVIC PA, HILHORST R, BENKOVIC SJ. ChemInform Abstract: Catalytic Antibodies with Acyl-Transfer Capabilities: Mechanistic and Kinetic Investigations. Cheminform. 22: no-no. DOI: 10.1002/chin.199115055 |
0.435 |
|
| 2009 |
Frederick MO, De Lamo Marin S, Janda KD, Nicolaou KC, Dickerson TJ. Monoclonal antibodies with orthogonal azaspiracid epitopes. Chembiochem : a European Journal of Chemical Biology. 10: 1625-9. PMID 19492388 DOI: 10.1002/Cbic.200900201 |
0.633 |
|
| 2009 |
Moreno AY, Janda KD. Immunopharmacotherapy: vaccination strategies as a treatment for drug abuse and dependence. Pharmacology, Biochemistry, and Behavior. 92: 199-205. PMID 19350728 DOI: 10.1016/J.Pbb.2009.01.015 |
0.778 |
|
| 2009 |
Treweek JB, Dickerson TJ, Janda KD. Drugs of abuse that mediate advanced glycation end product formation: a chemical link to disease pathology. Accounts of Chemical Research. 42: 659-69. PMID 19275211 DOI: 10.1021/Ar800247D |
0.633 |
|
| 2009 |
Fischer A, Nakai Y, Eubanks LM, Clancy CM, Tepp WH, Pellett S, Dickerson TJ, Johnson EA, Janda KD, Montal M. Bimodal modulation of the botulinum neurotoxin protein-conducting channel. Proceedings of the National Academy of Sciences of the United States of America. 106: 1330-5. PMID 19164566 DOI: 10.1073/Pnas.0812839106 |
0.593 |
|
| 2009 |
Nakai Y, Tepp WH, Dickerson TJ, Johnson EA, Janda KD. Function-oriented synthesis applied to the anti-botulinum natural product toosendanin. Bioorganic & Medicinal Chemistry. 17: 1152-7. PMID 19131252 DOI: 10.1016/J.Bmc.2008.12.042 |
0.623 |
|
| 2009 |
Zhou H, Zhou B, Pellett S, Johnson EA, Janda KD. Selection and characterization of a human monoclonal neutralizing antibody for Clostridium Botulinum neurotoxin serotype B. Bioorganic & Medicinal Chemistry Letters. 19: 662-4. PMID 19112017 DOI: 10.1016/J.Bmcl.2008.12.055 |
0.334 |
|
| 2009 |
Treweek JB, Moreno AY, Janda KD. SLEEPLESS-ness and insomnia in fruit flies. Angewandte Chemie (International Ed. in English). 48: 438-40. PMID 19072956 DOI: 10.1002/Anie.200804552 |
0.724 |
|
| 2009 |
Treweek J, Moreno A, Janda K. Schlaflose Fruchtfliegen durch SLEEPLESS-Verlust Angewandte Chemie. 121: 446-448. DOI: 10.1002/Ange.200804552 |
0.717 |
|
| 2008 |
Mayorov AV, Amara N, Chang JY, Moss JA, Hixon MS, Ruiz DI, Meijler MM, Zorrilla EP, Janda KD. Catalytic antibody degradation of ghrelin increases whole-body metabolic rate and reduces refeeding in fasting mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 17487-92. PMID 18981425 DOI: 10.1073/Pnas.0711808105 |
0.755 |
|
| 2008 |
Treweek JB, Sun C, Mayorov AV, Qi L, Levy CL, Roberts AJ, Dickerson TJ, Janda KD. Prevention of drug-induced memory impairment by immunopharmacotherapy. Journal of Medicinal Chemistry. 51: 6866-75. PMID 18921991 DOI: 10.1021/Jm800506V |
0.779 |
|
| 2008 |
Willis B, Eubanks LM, Dickerson TJ, Janda KD. The strange case of the botulinum neurotoxin: using chemistry and biology to modulate the most deadly poison. Angewandte Chemie (International Ed. in English). 47: 8360-79. PMID 18844202 DOI: 10.1002/Anie.200705531 |
0.632 |
|
| 2008 |
Park J, Dickerson TJ, Janda KD. Major sperm protein as a diagnostic antigen for onchocerciasis. Bioorganic & Medicinal Chemistry. 16: 7206-9. PMID 18632276 DOI: 10.1016/J.Bmc.2008.06.038 |
0.637 |
|
| 2008 |
Lowery CA, Dickerson TJ, Janda KD. Interspecies and interkingdom communication mediated by bacterial quorum sensing. Chemical Society Reviews. 37: 1337-46. PMID 18568160 DOI: 10.1039/B702781H |
0.577 |
|
| 2008 |
Zhou B, Pellett S, Tepp WH, Zhou H, Johnson EA, Janda KD. Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects. Febs Letters. 582: 1526-31. PMID 18396167 DOI: 10.1016/J.Febslet.2008.03.047 |
0.305 |
|
| 2008 |
Debler EW, Kaufmann GF, Meijler MM, Heine A, Mee JM, Pljevaljcic G, Di Bilio AJ, Schultz PG, Millar DP, Janda KD, Wilson IA, Gray HB, Lerner RA. Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex. Science (New York, N.Y.). 319: 1232-5. PMID 18309081 DOI: 10.1126/Science.1153445 |
0.47 |
|
| 2008 |
Kaufmann GF, Park J, Mee JM, Ulevitch RJ, Janda KD. The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone. Molecular Immunology. 45: 2710-4. PMID 18304641 DOI: 10.1016/J.Molimm.2008.01.010 |
0.316 |
|
| 2008 |
Zarebski LM, Vaughan K, Sidney J, Peters B, Grey H, Janda KD, Casadevall A, Sette A. Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum. Expert Review of Vaccines. 7: 55-74. PMID 18251694 DOI: 10.1586/14760584.7.1.55 |
0.333 |
|
| 2008 |
Willis B, Eubanks LM, Wood MR, Janda KD, Dickerson TJ, Lerner RA. Biologically templated organic polymers with nanoscale order. Proceedings of the National Academy of Sciences of the United States of America. 105: 1416-9. PMID 18216240 DOI: 10.1073/Pnas.0711308105 |
0.656 |
|
| 2008 |
Richardson HN, Zhao Y, Fekete EM, Funk CK, Wirsching P, Janda KD, Zorrilla EP, Koob GF. MPZP: a novel small molecule corticotropin-releasing factor type 1 receptor (CRF1) antagonist. Pharmacology, Biochemistry, and Behavior. 88: 497-510. PMID 18031798 DOI: 10.1016/j.pbb.2007.10.008 |
0.324 |
|
| 2008 |
Zhou B, Carney C, Janda KD. Selection and characterization of human antibodies neutralizing Bacillus anthracis toxin. Bioorganic & Medicinal Chemistry. 16: 1903-13. PMID 18023190 DOI: 10.1016/J.Bmc.2007.11.001 |
0.372 |
|
| 2008 |
Brogan AP, Dickerson TJ, Janda KD. ChemInform Abstract: Nornicotine-Organocatalyzed Aqueous Reduction of α,β-Unsaturated Aldehydes. Cheminform. 39. DOI: 10.1002/chin.200812079 |
0.524 |
|
| 2008 |
Willis B, Eubanks L, Dickerson T, Janda K. Der seltsame Fall des Botulinum-Neurotoxins: chemische und biologische Modulierung des tödlichsten aller Gifte Angewandte Chemie. 120: 8488-8507. DOI: 10.1002/Ange.200705531 |
0.563 |
|
| 2007 |
Brogan AP, Dickerson TJ, Janda KD. Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes. Chemical Communications (Cambridge, England). 4952-4. PMID 18361380 DOI: 10.1039/B713273E |
0.573 |
|
| 2007 |
Park J, Jagasia R, Kaufmann GF, Mathison JC, Ruiz DI, Moss JA, Meijler MM, Ulevitch RJ, Janda KD. Infection control by antibody disruption of bacterial quorum sensing signaling. Chemistry & Biology. 14: 1119-27. PMID 17961824 DOI: 10.1016/J.Chembiol.2007.08.013 |
0.606 |
|
| 2007 |
Capková K, Yoneda Y, Dickerson TJ, Janda KD. Synthesis and structure-activity relationships of second-generation hydroxamate botulinum neurotoxin A protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 6463-6. PMID 17951059 DOI: 10.1016/J.Bmcl.2007.09.103 |
0.597 |
|
| 2007 |
Zhou H, Zhou B, Ma H, Carney C, Janda KD. Selection and characterization of human monoclonal antibodies against Abrin by phage display. Bioorganic & Medicinal Chemistry Letters. 17: 5690-2. PMID 17764932 DOI: 10.1016/J.Bmcl.2007.07.053 |
0.329 |
|
| 2007 |
Dickerson TJ, McKenzie KM, Hoyt AS, Wood MR, Janda KD, Brenner SB, Lerner RA. Phage escape libraries for checkmate analysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12703-8. PMID 17646645 DOI: 10.1073/Pnas.0705362104 |
0.682 |
|
| 2007 |
Treweek J, Wee S, Koob GF, Dickerson TJ, Janda KD. Self-vaccination by methamphetamine glycation products chemically links chronic drug abuse and cardiovascular disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 11580-4. PMID 17592122 DOI: 10.1073/Pnas.0701328104 |
0.693 |
|
| 2007 |
Ino A, Dickerson TJ, Janda KD. Positional linker effects in haptens for cocaine immunopharmacotherapy. Bioorganic & Medicinal Chemistry Letters. 17: 4280-3. PMID 17531484 DOI: 10.1016/J.Bmcl.2007.05.032 |
0.637 |
|
| 2007 |
Debler EW, Kaufmann GF, Kirchdoerfer RN, Mee JM, Janda KD, Wilson IA. Crystal structures of a quorum-quenching antibody. Journal of Molecular Biology. 368: 1392-402. PMID 17400249 DOI: 10.1016/J.Jmb.2007.02.081 |
0.331 |
|
| 2007 |
Liu Y, Steiniger SC, Kim Y, Kaufmann GF, Felding-Habermann B, Janda KD. Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery. Molecular Pharmaceutics. 4: 435-47. PMID 17373820 DOI: 10.1021/Mp060122J |
0.449 |
|
| 2007 |
Xu Y, Hixon MS, Yamamoto N, McAllister LA, Wentworth AD, Wentworth P, Janda KD. Antibody-catalyzed anaerobic destruction of methamphetamine. Proceedings of the National Academy of Sciences of the United States of America. 104: 3681-6. PMID 17360412 DOI: 10.1073/Pnas.0611094104 |
0.354 |
|
| 2007 |
Brogan AP, Eubanks LM, Koob GF, Dickerson TJ, Janda KD. Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol. Journal of the American Chemical Society. 129: 3698-702. PMID 17335216 DOI: 10.1021/Ja070022M |
0.683 |
|
| 2007 |
Eubanks LM, Dickerson TJ, Janda KD. Technological advancements for the detection of and protection against biological and chemical warfare agents. Chemical Society Reviews. 36: 458-70. PMID 17325785 DOI: 10.1039/B615227A |
0.592 |
|
| 2007 |
McAllister LA, Hixon MS, Schwartz R, Kubitz DS, Janda KD. Synthesis and application of a novel ligand for affinity chromatography based removal of endotoxin from antibodies. Bioconjugate Chemistry. 18: 559-66. PMID 17315943 DOI: 10.1021/Bc0602984 |
0.308 |
|
| 2007 |
Eubanks LM, Hixon MS, Jin W, Hong S, Clancy CM, Tepp WH, Baldwin MR, Malizio CJ, Goodnough MC, Barbieri JT, Johnson EA, Boger DL, Dickerson TJ, Janda KD. An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists. Proceedings of the National Academy of Sciences of the United States of America. 104: 2602-7. PMID 17293454 DOI: 10.1073/Pnas.0611213104 |
0.627 |
|
| 2007 |
De Lamo Marin S, Xu Y, Meijler MM, Janda KD. Antibody catalyzed hydrolysis of a quorum sensing signal found in Gram-negative bacteria. Bioorganic & Medicinal Chemistry Letters. 17: 1549-52. PMID 17254784 DOI: 10.1016/J.Bmcl.2006.12.118 |
0.336 |
|
| 2007 |
Steiniger SC, Altobell LJ, Zhou B, Janda KD. Selection of human antibodies against cell surface-associated oligomeric anthrax protective antigen. Molecular Immunology. 44: 2749-55. PMID 17210180 DOI: 10.1016/J.Molimm.2006.11.011 |
0.356 |
|
| 2007 |
McKenzie KM, Mee JM, Rogers CJ, Hixon MS, Kaufmann GF, Janda KD. Identification and characterization of single chain anti-cocaine catalytic antibodies. Journal of Molecular Biology. 365: 722-31. PMID 17084858 DOI: 10.1016/J.Jmb.2006.10.031 |
0.354 |
|
| 2006 |
Dickerson TJ, Janda KD. The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication. Acs Chemical Biology. 1: 359-69. PMID 17163773 DOI: 10.1021/Cb600179D |
0.619 |
|
| 2006 |
Eubanks LM, Rogers CJ, Beuscher AE, Koob GF, Olson AJ, Dickerson TJ, Janda KD. A molecular link between the active component of marijuana and Alzheimer's disease pathology. Molecular Pharmaceutics. 3: 773-7. PMID 17140265 DOI: 10.1021/Mp060066M |
0.648 |
|
| 2006 |
Rogers CJ, Eubanks LM, Dickerson TJ, Janda KD. Unexpected acetylcholinesterase activity of cocaine esterases. Journal of the American Chemical Society. 128: 15364-5. PMID 17131989 DOI: 10.1021/JA066241+ |
0.61 |
|
| 2006 |
Brogan AP, Dickerson TJ, Janda KD. Enamine-based aldol organocatalysis in water: are they really "all wet"? Angewandte Chemie (International Ed. in English). 45: 8100-2. PMID 17001595 DOI: 10.1002/Anie.200601392 |
0.561 |
|
| 2006 |
Zorrilla EP, Iwasaki S, Moss JA, Chang J, Otsuji J, Inoue K, Meijler MM, Janda KD. Vaccination against weight gain. Proceedings of the National Academy of Sciences of the United States of America. 103: 13226-31. PMID 16891413 DOI: 10.1073/Pnas.0605376103 |
0.614 |
|
| 2006 |
Kim Y, Lillo AM, Steiniger SC, Liu Y, Ballatore C, Anichini A, Mortarini R, Kaufmann GF, Zhou B, Felding-Habermann B, Janda KD. Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand. Biochemistry. 45: 9434-44. PMID 16878978 DOI: 10.1021/Bi060264J |
0.439 |
|
| 2006 |
Xu Y, Lu H, Kennedy JP, Yan X, McAllister LA, Yamamoto N, Moss JA, Boldt GE, Jiang S, Janda KD. Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formation. Journal of Combinatorial Chemistry. 8: 531-9. PMID 16827565 DOI: 10.1021/Cc0600167 |
0.591 |
|
| 2006 |
Boldt GE, Kennedy JP, Hixon MS, McAllister LA, Barbieri JT, Tzipori S, Janda KD. Synthesis, characterization and development of a high-throughput methodology for the discovery of botulinum neurotoxin a inhibitors. Journal of Combinatorial Chemistry. 8: 513-21. PMID 16827563 DOI: 10.1021/Cc060010H |
0.316 |
|
| 2006 |
Ma H, Zhou B, Kim Y, Janda KD. A cyclic peptide-polymer probe for the detection of Clostridium botulinum neurotoxin serotype A. Toxicon : Official Journal of the International Society On Toxinology. 47: 901-8. PMID 16730044 DOI: 10.1016/J.Toxicon.2006.03.003 |
0.44 |
|
| 2006 |
Moss JA, Stokols S, Hixon MS, Ashley FT, Chang JY, Janda KD. Solid-phase synthesis and kinetic characterization of fluorogenic enzyme-degradable hydrogel cross-linkers. Biomacromolecules. 7: 1011-6. PMID 16602715 DOI: 10.1021/Bm051001S |
0.597 |
|
| 2006 |
McAllister LA, Hixon MS, Kennedy JP, Dickerson TJ, Janda KD. Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: a new wrinkle in botulinum neurotoxin. Journal of the American Chemical Society. 128: 4176-7. PMID 16568962 DOI: 10.1021/Ja057699Z |
0.617 |
|
| 2006 |
Boldt GE, Dickerson TJ, Janda KD. Emerging chemical and biological approaches for the preparation of discovery libraries. Drug Discovery Today. 11: 143-8. PMID 16533712 DOI: 10.1016/S1359-6446(05)03697-4 |
0.619 |
|
| 2006 |
Kaufmann GF, Sartorio R, Lee SH, Mee JM, Altobell LJ, Kujawa DP, Jeffries E, Clapham B, Meijler MM, Janda KD. Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing. Journal of the American Chemical Society. 128: 2802-3. PMID 16506750 DOI: 10.1021/Ja0578698 |
0.313 |
|
| 2006 |
Zhu X, Dickerson TJ, Rogers CJ, Kaufmann GF, Mee JM, McKenzie KM, Janda KD, Wilson IA. Complete reaction cycle of a cocaine catalytic antibody at atomic resolution. Structure (London, England : 1993). 14: 205-16. PMID 16472740 DOI: 10.1016/J.Str.2005.10.014 |
0.637 |
|
| 2006 |
Xu Y, Shi J, Yamamoto N, Moss JA, Vogt PK, Janda KD. A credit-card library approach for disrupting protein-protein interactions. Bioorganic & Medicinal Chemistry. 14: 2660-73. PMID 16384710 DOI: 10.1016/J.Bmc.2005.11.052 |
0.58 |
|
| 2006 |
Shigenaga A, Moss JA, Ashley FT, Kaufmann GF, Janda KD. Solid-phase synthesis and cyclative cleavage of quorum sensing depsipeptide analogues by acylphenyldiazene activation Synlett. 551-554. DOI: 10.1055/S-2006-932468 |
0.608 |
|
| 2006 |
Rogers CJ, Dickerson TJ, Janda KD. Kinetic isotope and thermodynamic analysis of the nornicotine-catalyzed aqueous aldol reaction Tetrahedron. 62: 352-356. DOI: 10.1016/J.Tet.2005.09.094 |
0.602 |
|
| 2005 |
Dickerson TJ, Janda KD. Retraction note to: Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy Aaps Journal. 14: 542-542. PMID 22585345 DOI: 10.1208/S12248-012-9365-2 |
0.62 |
|
| 2005 |
Matsushita H, Yamamoto N, Meijler MM, Wirsching P, Lerner RA, Matsushita M, Janda KD. Chiral sensing using a blue fluorescent antibody. Molecular Biosystems. 1: 303-6. PMID 16880995 DOI: 10.1039/B511408J |
0.478 |
|
| 2005 |
Dickerson TJ, Janda KD. Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy. The Aaps Journal. 7: E579-86. PMID 16353936 DOI: 10.1208/aapsj070359 |
0.62 |
|
| 2005 |
Kim Y, Lillo A, Moss JA, Janda KD. A contiguous stretch of methionine residues mediates the energy-dependent internalization mechanism of a cell-penetrating peptide. Molecular Pharmaceutics. 2: 528-35. PMID 16323960 DOI: 10.1021/Mp050035B |
0.628 |
|
| 2005 |
Shute TS, Matsushita M, Dickerson TJ, La Clair JJ, Janda KD, Burkart MD. A site-specific bifunctional protein labeling system for affinity and fluorescent analysis. Bioconjugate Chemistry. 16: 1352-5. PMID 16287229 DOI: 10.1021/Bc050213J |
0.616 |
|
| 2005 |
Qi L, Yamamoto N, Meijler MM, Altobell LJ, Koob GF, Wirsching P, Janda KD. Delta9-tetrahydrocannabinol immunochemical studies: haptens, monoclonal antibodies, and a convenient synthesis of radiolabeled delta9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 48: 7389-99. PMID 16279798 DOI: 10.1021/Jm050442R |
0.508 |
|
| 2005 |
Toker JD, Tremblay MR, Yli-Kauhaluoma J, Wentworth AD, Zhou B, Wentworth P, Janda KD. Exploring the scope of the 29G12 antibody catalyzed 1,3-dipolar cycloaddition reaction. The Journal of Organic Chemistry. 70: 7810-5. PMID 16277300 DOI: 10.1021/Jo050410B |
0.766 |
|
| 2005 |
Dickerson TJ, Beuscher AE, Rogers CJ, Hixon MS, Yamamoto N, Xu Y, Olson AJ, Janda KD. Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library. Biochemistry. 44: 14845-53. PMID 16274232 DOI: 10.1021/Bi051613X |
0.607 |
|
| 2005 |
Matsushita M, Meijler MM, Wirsching P, Lerner RA, Janda KD. A blue fluorescent antibody-cofactor sensor for mercury. Organic Letters. 7: 4943-6. PMID 16235928 DOI: 10.1021/Ol051919W |
0.477 |
|
| 2005 |
Eubanks LM, Dickerson TJ, Janda KD. Vitamin B2-mediated cellular photoinhibition of botulinum neurotoxin A. Febs Letters. 579: 5361-4. PMID 16198354 DOI: 10.1016/J.Febslet.2005.08.072 |
0.601 |
|
| 2005 |
Xu Y, Yamamoto N, Ruiz DI, Kubitz DS, Janda KD. Squaric monoamide monoester as a new class of reactive immunization hapten for catalytic antibodies Bioorganic and Medicinal Chemistry Letters. 15: 4304-4307. PMID 16046128 DOI: 10.1016/J.Bmcl.2005.06.052 |
0.344 |
|
| 2005 |
Brogan AP, Dickerson TJ, Boldt GE, Janda KD. Altered retinoid homeostasis catalyzed by a nicotine metabolite: implications in macular degeneration and normal development. Proceedings of the National Academy of Sciences of the United States of America. 102: 10433-8. PMID 16014706 DOI: 10.1073/Pnas.0504721102 |
0.591 |
|
| 2005 |
Rogers CJ, Mee JM, Kaufmann GF, Dickerson TJ, Janda KD. Toward cocaine esterase therapeutics. Journal of the American Chemical Society. 127: 10016-7. PMID 16011362 DOI: 10.1021/Ja053086A |
0.614 |
|
| 2005 |
Carrera MR, Trigo JM, Wirsching P, Roberts AJ, Janda KD. Evaluation of the anticocaine monoclonal antibody GNC92H2 as an immunotherapy for cocaine overdose. Pharmacology, Biochemistry, and Behavior. 81: 709-14. PMID 16005948 DOI: 10.1016/J.Pbb.2005.04.018 |
0.537 |
|
| 2005 |
Dickerson TJ, Kaufmann GF, Janda KD. Bacteriophage-mediated protein delivery into the central nervous system and its application in immunopharmacotherapy. Expert Opinion On Biological Therapy. 5: 773-81. PMID 15952908 DOI: 10.1517/14712598.5.6.773 |
0.624 |
|
| 2005 |
Rogers CJ, Dickerson TJ, Brogan AP, Janda KD. Hammett correlation of nornicotine analogues in the aqueous aldol reaction: implications for green organocatalysis. The Journal of Organic Chemistry. 70: 3705-8. PMID 15845010 DOI: 10.1021/Jo050161R |
0.599 |
|
| 2005 |
Kaufmann GF, Meijler MM, Sun C, Chen DW, Kujawa DP, Mee JM, Hoffman TZ, Wirsching P, Lerner RA, Janda KD. Enzymatic incorporation of an antibody-activated blue fluorophore into DNA. Angewandte Chemie (International Ed. in English). 44: 2144-8. PMID 15742317 DOI: 10.1002/Anie.200461143 |
0.48 |
|
| 2005 |
Reed NN, Dickerson TJ, Boldt GE, Janda KD. Enantioreversal in the sharpless asymmetric epoxidation reaction controlled by the molecular weight of a covalently appended achiral polymer. The Journal of Organic Chemistry. 70: 1728-31. PMID 15730294 DOI: 10.1021/Jo048009X |
0.601 |
|
| 2005 |
Meijler MM, Kaufmann GF, Qi L, Mee JM, Coyle AR, Moss JA, Wirsching P, Matsushita M, Janda KD. Fluorescent cocaine probes: a tool for the selection and engineering of therapeutic antibodies. Journal of the American Chemical Society. 127: 2477-84. PMID 15725002 DOI: 10.1021/Ja043935E |
0.628 |
|
| 2005 |
Moss JA, Lillo A, Kim YS, Gao C, Ditzel H, Janda KD. A dimerization "switch" in the internalization mechanism of a cell-penetrating peptide. Journal of the American Chemical Society. 127: 538-9. PMID 15643874 DOI: 10.1021/Ja0443171 |
0.66 |
|
| 2005 |
Kaufmann GF, Sartorio R, Lee SH, Rogers CJ, Meijler MM, Moss JA, Clapham B, Brogan AP, Dickerson TJ, Janda KD. Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones. Proceedings of the National Academy of Sciences of the United States of America. 102: 309-14. PMID 15623555 DOI: 10.1073/Pnas.0408639102 |
0.717 |
|
| 2005 |
Xu Y, Yamamoto N, Janda KD. Catalytic antibodies: hapten design strategies and screening methods. Bioorganic & Medicinal Chemistry. 12: 5247-68. PMID 15388154 DOI: 10.1016/J.Bmc.2004.03.077 |
0.347 |
|
| 2005 |
Debler EW, Kaufmann GF, Di Bilio A, Gray HB, Lerner RA, Janda KD, Wilson IA. Structural basis for blue and purple fluorescence of antibody-stilbene complexes Acta Crystallographica Section a Foundations of Crystallography. 61: c229-c230. DOI: 10.1107/S0108767305090227 |
0.474 |
|
| 2005 |
Rogers CJ, Dickerson TJ, Wentworth P, Janda KD. A high-swelling reagent scaffold suitable for use in aqueous and organic solvents Tetrahedron. 61: 12140-12144. DOI: 10.1055/S-2006-931979 |
0.585 |
|
| 2005 |
Reed NN, Dickerson TJ, oldt GEB, Janda KD. Molecular Weight Induced Enantioreversal in Sharpless Asymmetric Epoxidation Synfacts. 2005: 44-44. DOI: 10.1055/S-2005-869913 |
0.572 |
|
| 2004 |
Meijler MM, Matsushita M, Wirsching P, Janda KD. Development of immunopharmacotherapy against drugs of abuse. Current Drug Discovery Technologies. 1: 77-89. PMID 16472221 DOI: 10.2174/1570163043484851 |
0.326 |
|
| 2004 |
Dickerson TJ, Reed NN, LaClair JJ, Janda KD. A precipitator for the detection of thiophilic metals in aqua. Journal of the American Chemical Society. 126: 16582-6. PMID 15600364 DOI: 10.1021/Ja045798R |
0.59 |
|
| 2004 |
Felding-Habermann B, Lerner RA, Lillo A, Zhuang S, Weber MR, Arrues S, Gao C, Mao S, Saven A, Janda KD. Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America. 101: 17210-5. PMID 15563590 DOI: 10.1073/Pnas.0407869101 |
0.646 |
|
| 2004 |
Kim YS, Moss JA, Janda KD. Biological tuning of synthetic tactics in solid-phase synthesis: application to A beta(1-42). The Journal of Organic Chemistry. 69: 7776-8. PMID 15498016 DOI: 10.1021/Jo048922Y |
0.576 |
|
| 2004 |
Dickerson TJ, Lovell T, Meijler MM, Noodleman L, Janda KD. Nornicotine aqueous aldol reactions: synthetic and theoretical investigations into the origins of catalysis. The Journal of Organic Chemistry. 69: 6603-9. PMID 15387581 DOI: 10.1021/Jo048894J |
0.614 |
|
| 2004 |
Dickerson TJ, Yamamoto N, Ruiz DI, Janda KD. Immunological consequences of methamphetamine protein glycation. Journal of the American Chemical Society. 126: 11446-7. PMID 15366884 DOI: 10.1021/Ja047690H |
0.642 |
|
| 2004 |
Carrera MR, Meijler MM, Janda KD. Cocaine pharmacology and current pharmacotherapies for its abuse. Bioorganic & Medicinal Chemistry. 12: 5019-30. PMID 15351386 DOI: 10.1016/J.Bmc.2004.06.018 |
0.547 |
|
| 2004 |
Dickerson TJ, Yamamoto N, Janda KD. Antibody-catalyzed oxidative degradation of nicotine using riboflavin. Bioorganic & Medicinal Chemistry. 12: 4981-7. PMID 15336277 DOI: 10.1016/J.Bmc.2004.07.006 |
0.628 |
|
| 2004 |
Lillo AM, Sun C, Gao C, Ditzel H, Parrish J, Gauss CM, Moss J, Felding-Habermann B, Wirsching P, Boger DL, Janda KD. A human single-chain antibody specific for integrin alpha3beta1 capable of cell internalization and delivery of antitumor agents. Chemistry & Biology. 11: 897-906. PMID 15271348 DOI: 10.1016/J.Chembiol.2004.04.018 |
0.703 |
|
| 2004 |
Carrera MR, Kaufmann GF, Mee JM, Meijler MM, Koob GF, Janda KD. Treating cocaine addiction with viruses. Proceedings of the National Academy of Sciences of the United States of America. 101: 10416-21. PMID 15226496 DOI: 10.1073/Pnas.0403795101 |
0.609 |
|
| 2004 |
Meijler MM, Hom LG, Kaufmann GF, McKenzie KM, Sun C, Moss JA, Matsushita M, Janda KD. Synthesis and biological validation of a ubiquitous quorum-sensing molecule. Angewandte Chemie (International Ed. in English). 43: 2106-8. PMID 15083457 DOI: 10.1002/Anie.200353150 |
0.572 |
|
| 2004 |
Ahn JM, Wentworth P, Janda KD. Probing lipase/esterase libraries for lipid A hydrolases--discovery of biocatalysts for the detoxification of bacterially-expressed recombinant protein. Chemical Communications (Cambridge, England). 364-5. PMID 14765210 DOI: 10.1039/B312662E |
0.53 |
|
| 2004 |
Carrera MR, Ashley JA, Hoffman TZ, Isomura S, Wirsching P, Koob GF, Janda KD. Investigations using immunization to attenuate the psychoactive effects of nicotine. Bioorganic & Medicinal Chemistry. 12: 563-70. PMID 14738965 DOI: 10.1016/J.Bmc.2003.11.029 |
0.605 |
|
| 2004 |
Kim YS, Moss JA, Janda KD. P1-175 Development of conformation-specific antibodies for neutralization of β-amyloid oligomers Neurobiology of Aging. 25: S145. DOI: 10.1016/S0197-4580(04)80488-3 |
0.596 |
|
| 2003 |
Matsushita M, Yoshida K, Yamamoto N, Wirsching P, Lerner RA, Janda KD. High-throughput screening by using a blue-fluorescent antibody sensor. Angewandte Chemie (International Ed. in English). 42: 5984-7. PMID 14679549 DOI: 10.1002/Anie.200352793 |
0.466 |
|
| 2003 |
Dickerson TJ, Tremblay MR, Hoffman TZ, Ruiz DI, Janda KD. Catalysis of the photo-Fries reaction: antibody-mediated stabilization of high energy states. Journal of the American Chemical Society. 125: 15395-401. PMID 14664584 DOI: 10.1021/Ja038016N |
0.648 |
|
| 2003 |
Wentworth P, Nieva J, Takeuchi C, Galve R, Wentworth AD, Dilley RB, DeLaria GA, Saven A, Babior BM, Janda KD, Eschenmoser A, Lerner RA. Evidence for ozone formation in human atherosclerotic arteries. Science (New York, N.Y.). 302: 1053-6. PMID 14605372 DOI: 10.1126/Science.1089525 |
0.438 |
|
| 2003 |
Moss JA, Coyle AR, Ahn JM, Meijler MM, Offer J, Janda KD. Tandem IMAC-HPLC purification of a cocaine-binding scFv antibody. Journal of Immunological Methods. 281: 143-8. PMID 14580888 DOI: 10.1016/J.Jim.2003.07.010 |
0.704 |
|
| 2003 |
Dickerson TJ, Janda KD. Glycation of the amyloid beta-protein by a nicotine metabolite: a fortuitous chemical dynamic between smoking and Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 8182-7. PMID 12815102 DOI: 10.1073/Pnas.1332847100 |
0.598 |
|
| 2003 |
Meijler MM, Matsushita M, Altobell LJ, Wirsching P, Janda KD. A new strategy for improved nicotine vaccines using conformationally constrained haptens. Journal of the American Chemical Society. 125: 7164-5. PMID 12797775 DOI: 10.1021/Ja034805T |
0.321 |
|
| 2003 |
Zhu X, Heine A, Monnat F, Houk KN, Janda KD, Wilson IA. Structural basis for antibody catalysis of a cationic cyclization reaction. Journal of Molecular Biology. 329: 69-83. PMID 12742019 DOI: 10.1016/S0022-2836(03)00406-6 |
0.325 |
|
| 2003 |
Gambs C, Dickerson TJ, Mahajan S, Pasternack LB, Janda KD. High-resolution diffusion-ordered spectroscopy to probe the microenvironment of JandaJel and Merrifield resins. The Journal of Organic Chemistry. 68: 3673-8. PMID 12713377 DOI: 10.1021/Jo034152Z |
0.594 |
|
| 2003 |
Redwan el-RM, Larsen NA, Zhou B, Wirsching P, Janda KD, Wilson IA. Expression and characterization of a humanized cocaine-binding antibody. Biotechnology and Bioengineering. 82: 612-8. PMID 12652485 DOI: 10.1002/Bit.10598 |
0.341 |
|
| 2003 |
Ahn JM, Wentworth P, Janda KD. Soluble polymer-supported convergent parallel library synthesis. Chemical Communications (Cambridge, England). 480-1. PMID 12638959 DOI: 10.1039/B210696E |
0.518 |
|
| 2003 |
Gao C, Mao S, Ronca F, Zhuang S, Quaranta V, Wirsching P, Janda KD. De novo identification of tumor-specific internalizing human antibody-receptor pairs by phage-display methods. Journal of Immunological Methods. 274: 185-97. PMID 12609544 DOI: 10.1016/S0022-1759(02)00522-7 |
0.504 |
|
| 2003 |
Cannizzaro CE, Ashley JA, Janda KD, Houk KN. Experimental determination of the absolute enantioselectivity of an antibody-catalyzed Diels-Alder reaction and theoretical explorations of the origins of stereoselectivity. Journal of the American Chemical Society. 125: 2489-506. PMID 12603137 DOI: 10.1021/Ja020879D |
0.32 |
|
| 2003 |
Wentworth P, Wentworth AD, Zhu X, Wilson IA, Janda KD, Eschenmoser A, Lerner RA. Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens. Proceedings of the National Academy of Sciences of the United States of America. 100: 1490-3. PMID 12576548 DOI: 10.1073/Pnas.0437831100 |
0.509 |
|
| 2003 |
Wang Q, Raja KS, Janda KD, Lin T, Finn MG. Blue fluorescent antibodies as reporters of steric accessibility in virus conjugates. Bioconjugate Chemistry. 14: 38-43. PMID 12526690 DOI: 10.1021/Bc025587G |
0.314 |
|
| 2003 |
Isomura S, Ashley JA, Wirsching P, Janda KD. Antibody-catalyzed cleavage of the D-Ala-D-Lac depsipeptide: an immunological approach to the problem of vancomycin resistance. Bioorganic & Medicinal Chemistry Letters. 12: 861-4. PMID 11958980 DOI: 10.1016/S0960-894X(02)00047-1 |
0.316 |
|
| 2002 |
Jones LH, Altobell LJ, MacDonald MT, Boyle NA, Wentworth P, Lerner RA, Janda KD. Active immunization with a glycolipid transition state analogue protects against endotoxic shock. Angewandte Chemie (International Ed. in English). 41: 4241-4. PMID 12434351 DOI: 10.1002/1521-3773(20021115)41:22<4241::Aid-Anie4241>3.0.Co;2-N |
0.45 |
|
| 2002 |
Wentworth P, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD, Babior BM, Eschenmoser A, Lerner RA. Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation. Science (New York, N.Y.). 298: 2195-9. PMID 12434011 DOI: 10.1126/Science.1077642 |
0.716 |
|
| 2002 |
Gao C, Mao S, Ditzel HJ, Farnaes L, Wirsching P, Lerner RA, Janda KD. A cell-penetrating peptide from a novel pVII-pIX phage-displayed random peptide library. Bioorganic & Medicinal Chemistry. 10: 4057-65. PMID 12413859 DOI: 10.1016/S0968-0896(02)00340-1 |
0.594 |
|
| 2002 |
Dickerson TJ, Janda KD. A previously undescribed chemical link between smoking and metabolic disease. Proceedings of the National Academy of Sciences of the United States of America. 99: 15084-8. PMID 12403823 DOI: 10.1073/Pnas.222561699 |
0.608 |
|
| 2002 |
Lee KJ, Mao S, Sun C, Gao C, Blixt O, Arrues S, Hom LG, Kaufmann GF, Hoffman TZ, Coyle AR, Paulson J, Felding-Habermann B, Janda KD. Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen. Journal of the American Chemical Society. 124: 12439-46. PMID 12381184 DOI: 10.1021/Ja020737J |
0.508 |
|
| 2002 |
Dickerson TJ, Reed NN, Janda KD. Soluble polymers as scaffolds for recoverable catalysts and reagents. Chemical Reviews. 102: 3325-44. PMID 12371887 DOI: 10.1021/Cr010335E |
0.581 |
|
| 2002 |
Ahn JM, Boyle NA, MacDonald MT, Janda KD. Peptidomimetics and peptide backbone modifications. Mini Reviews in Medicinal Chemistry. 2: 463-73. PMID 12370047 DOI: 10.2174/1389557023405828 |
0.489 |
|
| 2002 |
Gao C, Mao S, Kaufmann G, Wirsching P, Lerner RA, Janda KD. A method for the generation of combinatorial antibody libraries using pIX phage display. Proceedings of the National Academy of Sciences of the United States of America. 99: 12612-6. PMID 12239343 DOI: 10.1073/Pnas.192467999 |
0.797 |
|
| 2002 |
Sun C, Wirsching P, Janda KD. Syntheses of dendritic linkers containing chlorambucil residues for the preparation of antibody-multidrug immunoconjugates. Bioorganic & Medicinal Chemistry Letters. 12: 2213-5. PMID 12127540 DOI: 10.1016/S0960-894X(02)00361-X |
0.359 |
|
| 2002 |
Delgado M, Lee KJ, Altobell L, Spanka C, Wentworth P, Janda KD. A parallel approach to the discovery of carrier delivery vehicles to enhance antigen immunogenicity. Journal of the American Chemical Society. 124: 4946-7. PMID 11982344 DOI: 10.1021/Ja025715B |
0.339 |
|
| 2002 |
Zhou B, Wirsching P, Janda KD. Human antibodies against spores of the genus Bacillus: a model study for detection of and protection against anthrax and the bioterrorist threat. Proceedings of the National Academy of Sciences of the United States of America. 99: 5241-6. PMID 11959974 DOI: 10.1073/Pnas.082121599 |
0.32 |
|
| 2002 |
Isomura S, Hoffman TZ, Wirsching P, Janda KD. Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration. Journal of the American Chemical Society. 124: 3661-8. PMID 11929256 DOI: 10.1021/Ja012376Y |
0.319 |
|
| 2002 |
Dickerson TJ, Janda KD. Aqueous aldol catalysis by a nicotine metabolite. Journal of the American Chemical Society. 124: 3220-1. PMID 11916401 DOI: 10.1021/Ja017774F |
0.603 |
|
| 2002 |
Wentworth P, Janda KD. Catalytic antibodies: structure and function. Cell Biochemistry and Biophysics. 35: 63-87. PMID 11898856 DOI: 10.1385/Cbb:35:1:63 |
0.329 |
|
| 2002 |
Kim GT, Wenz M, Park JI, Hasserodt J, Janda KD. Polyene substrates with unusual methylation patterns to probe the active sites of three catalytic antibodies. Bioorganic & Medicinal Chemistry. 10: 1249-62. PMID 11886788 DOI: 10.1016/S0968-0896(01)00402-3 |
0.352 |
|
| 2002 |
Moss JA, Dickerson TJ, Janda KD. Solid phase peptide synthesis on JandaJel™ resin Tetrahedron Letters. 43: 37-40. DOI: 10.1016/S0040-4039(01)02076-7 |
0.712 |
|
| 2001 |
Kozlov IA, Mao S, Xu Y, Huang X, Lee L, Sears PS, Gao C, Coyle AR, Janda KD, Wong CH. Synthesis of solid-supported mirror-image sugars: a novel method for selecting receptors for cellular-surface carbohydrates. Chembiochem : a European Journal of Chemical Biology. 2: 741-6. PMID 11948856 DOI: 10.1002/1439-7633(20011001)2:10<741::Aid-Cbic741>3.0.Co;2-B |
0.508 |
|
| 2001 |
Wentworth P, Jones LH, Wentworth AD, Zhu X, Larsen NA, Wilson IA, Xu X, Goddard WA, Janda KD, Eschenmoser A, Lerner RA. Antibody catalysis of the oxidation of water. Science (New York, N.Y.). 293: 1806-11. PMID 11546867 DOI: 10.1126/Science.1062722 |
0.487 |
|
| 2001 |
Córdova A, Janda KD. Synthesis and catalytic antibody functionalization of dendrimers Journal of the American Chemical Society. 123: 8248-8259. PMID 11516276 DOI: 10.1021/Ja001819F |
0.57 |
|
| 2001 |
Córdova A, Tremblay MR, Clapham B, Janda KD. A sequential application of kinetic resolution and polymer-supported scavenging for the isolation of chiral secondary alcohols. The Journal of Organic Chemistry. 66: 5645-8. PMID 11485501 DOI: 10.1021/Jo010529U |
0.476 |
|
| 2001 |
Jones LH, Harwig CW, Wentworth P, Simeonov A, Wentworth AD, Py S, Ashley JA, Lerner RA, Janda KD. Conversion of enediynes into quinones by antibody catalysis and in aqueous buffers: implications for an alternative enediyne therapeutic mechanism. Journal of the American Chemical Society. 123: 3607-8. PMID 11472138 DOI: 10.1021/Ja005864Z |
0.517 |
|
| 2001 |
Larsen NA, Zhou B, Heine A, Wirsching P, Janda KD, Wilson IA. Crystal structure of a cocaine-binding antibody. Journal of Molecular Biology. 311: 9-15. PMID 11469854 DOI: 10.1006/Jmbi.2001.4839 |
0.311 |
|
| 2001 |
Dickerson TJ, Reed NN, Janda KD. Regio-reactive resin: a platform for orthogonal loading using the polymer backbone and cross-linker. Bioorganic & Medicinal Chemistry Letters. 11: 1507-9. PMID 11412970 DOI: 10.1016/S0960-894X(01)00152-4 |
0.604 |
|
| 2001 |
Córdova A, Janda KD. A highly chemo- and stereoselective synthesis of β-keto esters via a polymer-supported lipase catalyzed transesterfication Journal of Organic Chemistry. 66: 1906-1909. PMID 11262145 DOI: 10.1021/Jo001478O |
0.488 |
|
| 2001 |
Chen DW, Beuscher AE, Stevens RC, Wirsching P, Lerner RA, Janda KD. Preparation of stilbene-tethered nonnatural nucleosides for use with blue-fluorescent antibodies. The Journal of Organic Chemistry. 66: 1725-32. PMID 11262119 DOI: 10.1021/Jo001676F |
0.514 |
|
| 2001 |
Matsushita M, Hoffman TZ, Ashley JA, Zhou B, Wirsching P, Janda KD. Cocaine catalytic antibodies: the primary importance of linker effects. Bioorganic & Medicinal Chemistry Letters. 11: 87-90. PMID 11206477 DOI: 10.1016/S0960-894X(00)00659-4 |
0.344 |
|
| 2001 |
Carrera MR, Ashley JA, Wirsching P, Koob GF, Janda KD. A second-generation vaccine protects against the psychoactive effects of cocaine. Proceedings of the National Academy of Sciences of the United States of America. 98: 1988-92. PMID 11172063 DOI: 10.1073/Pnas.98.4.1988 |
0.615 |
|
| 2001 |
Toy PH, Reger TS, Garibay P, Garno JC, Malikayil JA, Liu GY, Janda KD. Polytetrahydrofuran cross-linked polystyrene resins for solid-phase organic synthesis Journal of Combinatorial Chemistry. 3: 117-124. PMID 11148072 DOI: 10.1021/Cc000083F |
0.583 |
|
| 2001 |
Chen D, Kubiak RJ, Ashley JA, Janda KD. Reactive immunization elicits catalytic antibodies for polyester hydrolysis Journal of the Chemical Society-Perkin Transactions 1. 2796-2803. DOI: 10.1039/B105412K |
0.333 |
|
| 2001 |
Brümmer O, Hoffman TZ, Chen D, Janda KD. Antibody-catalyzed hydrolysis of oligomeric esters: a model for the degradation of polymeric materials Chemical Communications. 19-20. DOI: 10.1039/B008065I |
0.305 |
|
| 2001 |
Tremblay M, Dickerson T, Janda K. Advances in Antibody Catalysis of Cycloaddition Reactions Advanced Synthesis & Catalysis. 343: 577-585. DOI: 10.1002/1615-4169(200108)343:6/7<577::Aid-Adsc577>3.0.Co;2-Z |
0.618 |
|
| 2001 |
Tremblay MR, Dickerson TJ, Janda KD. Advances in Antibody Catalysis of Cycloaddition Reactions Advanced Synthesis and Catalysis. 343: 577-585. |
0.593 |
|
| 2000 |
Simeonov A, Matsushita M, Juban EA, Thompson EH, Hoffman TZ, Beuscher AE, Taylor MJ, Wirsching P, Rettig W, McCusker JK, Stevens RC, Millar DP, Schultz PG, Lerner RA, Janda KD. Blue-fluorescent antibodies. Science (New York, N.Y.). 290: 307-13. PMID 11030644 DOI: 10.1126/Science.290.5490.307 |
0.515 |
|
| 2000 |
Wentworth AD, Jones LH, Wentworth P, Janda KD, Lerner RA. Antibodies have the intrinsic capacity to destroy antigens. Proceedings of the National Academy of Sciences of the United States of America. 97: 10930-5. PMID 11005865 DOI: 10.1073/Pnas.97.20.10930 |
0.526 |
|
| 2000 |
Toy PH, Janda KD. Soluble polymer-supported organic synthesis Accounts of Chemical Research. 33: 546-554. PMID 10955985 DOI: 10.1021/Ar990140H |
0.574 |
|
| 2000 |
Toy PH, Reger TS, Janda KD. Soluble polymer bound cleavage reagents: a multipolymer strategy for the cleavage of tertiary amines from REM resin. Organic Letters. 2: 2205-7. PMID 10930244 DOI: 10.1021/Ol0059403 |
0.584 |
|
| 2000 |
Hasserodt J, Janda KD, Lerner RA. A class of 4-aza-lithocholic acid-derived haptens for the generation of catalytic antibodies with steroid synthase capabilities. Bioorganic & Medicinal Chemistry. 8: 995-1003. PMID 10882011 DOI: 10.1016/S0968-0896(00)00036-5 |
0.502 |
|
| 2000 |
Harwig CW, Hoffman TZ, Wentworth AD, Janda KD. A one-pot multistep approach to alpha-azido-phosphonate and phosphonothioate diesters: key intermediates in the synthesis of haptens for the generation of antibody ligases. Bioorganic & Medicinal Chemistry Letters. 10: 915-8. PMID 10853659 DOI: 10.1016/S0960-894X(00)00137-2 |
0.317 |
|
| 2000 |
Carrera MR, Ashley JA, Zhou B, Wirsching P, Koob GF, Janda KD. Cocaine vaccines: antibody protection against relapse in a rat model. Proceedings of the National Academy of Sciences of the United States of America. 97: 6202-6. PMID 10823960 DOI: 10.1073/Pnas.97.11.6202 |
0.623 |
|
| 2000 |
Toker JD, Wentworth P, Hu Y, Houk KN, Janda KD. Antibody-catalysis of a bimolecular asymmetric 1,3-dipolar cycloaddition reaction [15] Journal of the American Chemical Society. 122: 3244-3245. DOI: 10.1021/Ja994423G |
0.787 |
|
| 2000 |
Hasserodt J, Janda KD, Lerner RA. Antibodies mimic natural oxidosqualene-cyclase action in steroid ring a formation Journal of the American Chemical Society. 122: 40-45. DOI: 10.1021/Ja993054L |
0.515 |
|
| 2000 |
Toy PH, Janda KD. ChemInform Abstract: Soluble Polymer-Supported Organic Synthesis Cheminform. 31: no-no. DOI: 10.1002/CHIN.200044261 |
0.519 |
|
| 1999 |
Sieber F, Wentworth P, Toker JD, Wentworth AD, Metz WA, Reed NN, Janda KD. Development and Application of a Poly(ethylene glycol)-Supported Triarylphosphine Reagent: Expanding the Sphere of Liquid-Phase Organic Synthesis. The Journal of Organic Chemistry. 64: 5188-5192. PMID 34237880 DOI: 10.1021/jo9903712 |
0.777 |
|
| 1999 |
Paschall CM, Hasserodt J, Jones T, Lerner RA, Janda KD, Christianson DW. Convergence of Catalytic Antibody and Terpene Cyclase Mechanisms: Polyene Cyclization Directed by Carbocation-π Interactions. Angewandte Chemie (International Ed. in English). 38: 1743-1747. PMID 29711206 DOI: 10.1002/(Sici)1521-3773(19990614)38:12<1743::Aid-Anie1743>3.0.Co;2-3 |
0.503 |
|
| 1999 |
Ashley JA, Lin CH, Wirsching P, Janda KD. Monitoring Chemical Warfare Agents: A New Method for the Detection of Methylphosphonic Acid. Angewandte Chemie (International Ed. in English). 38: 1793-1795. PMID 29711182 DOI: 10.1002/(Sici)1521-3773(19990614)38:12<1793::Aid-Anie1793>3.0.Co;2-U |
0.307 |
|
| 1999 |
Córdova A, Reed NN, Ashley JA, Janda KD. Convenient synthesis of L-proline benzyl ester. Bioorganic & Medicinal Chemistry Letters. 9: 3119-22. PMID 10560736 DOI: 10.1016/S0960-894X(99)00546-6 |
0.494 |
|
| 1999 |
Spivak DA, Hoffman TZ, Moore AH, Taylor MJ, Janda KD. A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis. Bioorganic & Medicinal Chemistry. 7: 1145-50. PMID 10428386 DOI: 10.1016/S0968-0896(99)00026-7 |
0.324 |
|
| 1999 |
Mao S, Gao C, Lo CH, Wirsching P, Wong CH, Janda KD. Phage-display library selection of high-affinity human single-chain antibodies to tumor-associated carbohydrate antigens sialyl Lewisx and Lewisx. Proceedings of the National Academy of Sciences of the United States of America. 96: 6953-8. PMID 10359820 DOI: 10.1073/Pnas.96.12.6953 |
0.557 |
|
| 1999 |
Gao C, Mao S, Lo CH, Wirsching P, Lerner RA, Janda KD. Making artificial antibodies: a format for phage display of combinatorial heterodimeric arrays. Proceedings of the National Academy of Sciences of the United States of America. 96: 6025-30. PMID 10339535 DOI: 10.1073/Pnas.96.11.6025 |
0.634 |
|
| 1999 |
Janda KD, Wentworth AD. A Merging of Chemistry and Biology in Terms of Antibody Catalysis Phosphorus, Sulfur, and Silicon and the Related Elements. 144: 117-120. DOI: 10.1080/10426509908546196 |
0.333 |
|
| 1999 |
Wentworth P, Janda KD. Antibody catalysis of phosphodiester hydrolysis a survey of hapten strategies Phosphorus Sulfur and Silicon and the Related Elements. 144: 247-250. DOI: 10.1080/10426509908039543 |
0.34 |
|
| 1999 |
Garibay P, Toy PH, Hoeg-Jensen T, Janda KD. Application of a New Solid-Phase Resin: Benzamide ortho-Lithiation and the Synthesis of a Phthalide Library Synlett. 1999: 1438-1440. DOI: 10.1055/S-1999-2863 |
0.573 |
|
| 1999 |
Taylor MJ, Yli-Kauhaluoma JT, Ashley JA, Wirsching P, Lerner RA, Janda KD. The α-ketoamide group: A new motif for the elicitation of catalytic antibodies for acyl-transfer reactions Journal of the Chemical Society - Perkin Transactions 1. 1133-1134. DOI: 10.1039/A902475A |
0.646 |
|
| 1999 |
Sieber F, Wentworth P, Toker JD, Wentworth AD, Metz WA, Reed NN, Janda KD. Development and application of a poly(ethylene glycol)-supported triarylphosphine reagent: Expanding the sphere of liquid-phase organic synthesis Journal of Organic Chemistry. 64: 5188-5192. DOI: 10.1021/Jo9903712 |
0.775 |
|
| 1999 |
Datta A, Wentworth, P, Shaw JP, Simeonov A, Janda KD. Catalytically Distinct Antibodies Prepared by the Reactive Immunization versus Transition State Analogue Hapten Manifolds Journal of the American Chemical Society. 121: 10461-10467. DOI: 10.1021/Ja991274T |
0.312 |
|
| 1999 |
Gao C, Brümmer O, Mao S, Janda KD. Selection of Human Metalloantibodies from a Combinatorial Phage Single-Chain Antibody Library Journal of the American Chemical Society. 121: 6517-6518. DOI: 10.1021/Ja990966E |
0.533 |
|
| 1999 |
Brümmer O, Wentworth P, Weiner DP, Janda KD. Phosphorodithioates: synthesis and evaluation of new haptens for the generation of antibody acyl transferases Tetrahedron Letters. 40: 7307-7310. DOI: 10.1016/S0040-4039(99)01501-4 |
0.31 |
|
| 1999 |
Toy PH, Janda KD. New supports for solid-phase organic synthesis: Development of polystyrene resins containing tetrahydrofuran derived cross-linkers Tetrahedron Letters. 40: 6329-6332. DOI: 10.1016/S0040-4039(99)01251-4 |
0.577 |
|
| 1999 |
Brümmer O, Gao C, Mao S, Weiner DP, Janda KD. Design, synthesis and characterization of panning agents for the selection of metalloantibodies Letters in Peptide Science. 6: 295-302. DOI: 10.1007/Bf02443425 |
0.511 |
|
| 1999 |
Paschall CM, Hasserodt J, Jones T, Lerner RA, Janda KD, Christianson DW. Convergence of catalytic antibody and terpene cyclase mechanisms: Polyene cyclization directed by carbocation - π interactions Angewandte Chemie - International Edition. 38: 1743-1747. DOI: 10.1002/(SICI)1521-3773(19990614)38:12<1743::AID-ANIE1743>3.0.CO;2-3 |
0.427 |
|
| 1999 |
Paschall CM, Hasserodt J, Jones T, Lerner RA, Janda KD, Christianson DW. Konvergenz der Mechanismen eines katalytischen Antikörpers und einer Terpen-Cyclase: eine durch Carbokation-π-Elektronen-Wechselwirkung gesteuerte Polyencyclisierung Angewandte Chemie. 111: 1859-1864. DOI: 10.1002/(Sici)1521-3757(19990614)111:12<1859::Aid-Ange1859>3.0.Co;2-F |
0.407 |
|
| 1998 |
Wentworth P, Liu Y, Wentworth AD, Fan P, Foley MJ, Janda KD. A bait and switch hapten strategy generates catalytic antibodies for phosphodiester hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 95: 5971-5. PMID 9600901 DOI: 10.1073/Pnas.95.11.5971 |
0.345 |
|
| 1998 |
Heine A, Stura EA, Yli-Kauhaluoma JT, Gao C, Deng Q, Beno BR, Houk KN, Janda KD, Wilson IA. An antibody exo Diels-Alderase inhibitor complex at 1.95 angstrom resolution. Science (New York, N.Y.). 279: 1934-40. PMID 9506943 DOI: 10.1126/Science.279.5358.1934 |
0.679 |
|
| 1998 |
Yoon J, Cho CW, Han H, Janda KD. Solution and soluble polymer syntheses of 3-aminoimidazoline-2,4-diones Chemical Communications. 2703-2704. DOI: 10.1039/A807067I |
0.434 |
|
| 1998 |
Han H, Yoon J, Janda KD. An Efficient Asymmetric Route to 2,3-Diaminobutanoic Acids The Journal of Organic Chemistry. 63: 2045-2048. DOI: 10.1021/Jo9720391 |
0.453 |
|
| 1998 |
Taylor MJ, Hoffman TZ, Yli-Kauhaluoma JT, Lerner RA, Janda KD. A light-activated antibody catalyst Journal of the American Chemical Society. 120: 12783-12790. DOI: 10.1021/Ja982711R |
0.659 |
|
| 1998 |
Gao C, Lavey BJ, Lo CL, Datta A, Wentworth P, Janda KD. Direct Selection for Catalysis from Combinatorial Antibody Libraries Using a Boronic Acid Probe: Primary Amide Bond Hydrolysis Journal of the American Chemical Society. 120: 2211-2217. DOI: 10.1021/Ja9720220 |
0.546 |
|
| 1998 |
Yli-Kauhaluoma JT, Harwig CW, Wentworth P, Janda KD. Unexpected 1,3-oxazolidine formation in the attempted oxidation of N-aryl-N-methyl substituted β-amino alcohols using pyridinium dichromate Tetrahedron Letters. 39: 2269-2272. DOI: 10.1016/S0040-4039(98)00289-5 |
0.497 |
|
| 1997 |
Gao C, Lin CH, Lo CH, Mao S, Wirsching P, Lerner RA, Janda KD. Making chemistry selectable by linking it to infectivity. Proceedings of the National Academy of Sciences of the United States of America. 94: 11777-82. PMID 9342313 DOI: 10.1073/Pnas.94.22.11777 |
0.636 |
|
| 1997 |
Lin CH, Hoffman TZ, Wirsching P, Barbas CF, Janda KD, Lerner RA. On roads not taken in the evolution of protein catalysts: antibody steroid isomerases that use an enamine mechanism. Proceedings of the National Academy of Sciences of the United States of America. 94: 11773-6. PMID 9342312 DOI: 10.1073/Pnas.94.22.11773 |
0.52 |
|
| 1997 |
Janda KD, Lo LC, Lo CH, Sim MM, Wang R, Wong CH, Lerner RA. Chemical selection for catalysis in combinatorial antibody libraries. Science (New York, N.Y.). 275: 945-8. PMID 9020070 DOI: 10.1126/Science.275.5302.945 |
0.511 |
|
| 1997 |
Lo CL, Wentworth P, Jung KW, Yoon J, Ashley JA, Janda KD. Reactive Immunization Strategy Generates Antibodies with High Catalytic Proficiencies Journal of the American Chemical Society. 119: 10251-10252. DOI: 10.1021/Ja971442M |
0.504 |
|
| 1997 |
Hasserodt J, Janda KD, Lerner RA. Formation of bridge-methylated decalins by antibody-catalyzed tandem cationic cyclization Journal of the American Chemical Society. 119: 5993-5998. DOI: 10.1021/Ja970675A |
0.513 |
|
| 1997 |
Li T, Lerner RA, Janda KD. Antibody-Catalyzed Cationic Reactions: Rerouting of Chemical Transformations via Antibody Catalysis Accounts of Chemical Research. 30: 115-121. DOI: 10.1021/Ar960172U |
0.51 |
|
| 1997 |
Hasserodt J, Janda KD. Syntheses of octahydroquinoline-N-oxides: Haptens designed to elicit catalytic antibodies that control a terpenoid-like cascade cyclisation Tetrahedron. 53: 11237-11256. DOI: 10.1016/S0040-4020(97)00715-1 |
0.321 |
|
| 1996 |
Li T, Janda KD, Lerner RA. Cationic cyclopropanation by antibody catalysis Nature. 379: 326-327. PMID 8552185 DOI: 10.1038/379326a0 |
0.451 |
|
| 1996 |
Heine A, Stura EA, Janda KD, Barbas III CF, Lerner RA, Wilson IA. Structural studies of catalytic antibodies Acta Crystallographica Section a Foundations of Crystallography. 52: C220-C220. DOI: 10.1107/S0108767396090587 |
0.317 |
|
| 1996 |
Hasserodt J, Janda KD, Lerner RA. Antibody catalyzed terpenoid cyclization Journal of the American Chemical Society. 118: 11654-11655. DOI: 10.1021/Ja954316W |
0.516 |
|
| 1996 |
Yli-Kauhaluoma JT, Ashley JA, Lo CL, Coakley J, Wirsching P, Janda KD. Catalytic Antibodies with Peptidyl−Prolyl Cis−Trans Isomerase Activity Journal of the American Chemical Society. 118: 5496-5497. DOI: 10.1021/Ja954206P |
0.564 |
|
| 1996 |
Sakurai M, Wirsching P, Janda KD. Design and synthesis of a cocaine-diamide hapten for vaccine development Tetrahedron Letters. 37: 5479-5482. DOI: 10.1016/0040-4039(96)01170-7 |
0.315 |
|
| 1996 |
Lo CHL, Gao C, Mao S, Matsui K, Lerner RA, Janda KD. Chain shuffling: Investigations into the specificity and selectivity of antibody catalysis Israel Journal of Chemistry. 36: 195-198. DOI: 10.1002/Ijch.199600026 |
0.652 |
|
| 1995 |
Wirsching P, Ashley JA, Lo CHL, Janda KD, Lerner RA. Reactive immunization Science. 270: 1775-1782. PMID 8525366 |
0.449 |
|
| 1995 |
Fenniri H, Janda KD, Lerner RA. Encoded reaction cassette for the highly sensitive detection of the making and breaking of chemical bonds Proceedings of the National Academy of Sciences of the United States of America. 92: 2278-2282. PMID 7892261 DOI: 10.1073/Pnas.92.6.2278 |
0.478 |
|
| 1995 |
Lerner RA, Janda KD. Catalytic antibodies: evolution of protein function in real time Exs. 73: 121-138. PMID 7579971 |
0.451 |
|
| 1995 |
Han H, Wolfe MM, Brenner S, Janda KD. Liquid-phase combinatorial synthesis Proceedings of the National Academy of Sciences of the United States of America. 92: 6419-6423. PMID 7541541 DOI: 10.1073/Pnas.92.14.6419 |
0.323 |
|
| 1995 |
Carrera MR, Ashley JA, Parsons LH, Wirsching P, Koob GF, Janda KD. Suppression of psychoactive effects of cocaine by active immunization. Nature. 378: 727-30. PMID 7501020 DOI: 10.1038/378727A0 |
0.601 |
|
| 1995 |
Yli-Kauhaluoma JT, Ashley JA, Lo C, Tucker L, Wolfe MM, Janda KD. Anti-Metallocene Antibodies: A New Approach to Enantioselective Catalysis of the Diels-Alder Reaction Journal of the American Chemical Society. 117: 7041-7047. DOI: 10.1021/Ja00132A001 |
0.567 |
|
| 1995 |
Janda KD, Shevlin CG, Lerner RA. Oxepane synthesis along a disfavored pathway: The rerouting of a chemical reaction using a catalytic antibody Journal of the American Chemical Society. 117: 2659-2660. DOI: 10.1021/Ja00114A035 |
0.511 |
|
| 1995 |
Li T, Janda KD, Hilton S, Lerner RA. An antibody-catalyzed nucleophilic substitution reaction at a primary carbon that appears to proceed by an ionization mechanism Journal of the American Chemical Society. 117: 2367-2368. DOI: 10.1021/Ja00113A033 |
0.484 |
|
| 1995 |
Li T, Hilton S, Janda KD. The Potential Application of Catalytic Antibodies to Protecting Group Removal: Catalytic Antibodies with Broad Substrate Tolerance Journal of the American Chemical Society. 117: 2123-2127. DOI: 10.1021/Ja00113A001 |
0.335 |
|
| 1995 |
Rosenblum JS, Lo LC, Li T, Janda KD, Lerner RA. Antibody-catalyzed phosphate triester hydrolysis Angewandte Chemie (International Edition in English). 34: 2275-2277. DOI: 10.1002/Anie.199522751 |
0.51 |
|
| 1995 |
Rosenblum JS, Lo L, Li T, Janda KD, Lerner RA. Antikörper-katalysierte Hydrolyse von Phosphorsäuretriestern Angewandte Chemie. 107: 2448-2450. DOI: 10.1002/Ange.19951072023 |
0.407 |
|
| 1994 |
Li T, Janda KD, Ashley JA, Lerner RA. Antibody catalyzed cationic cyclization Science. 264: 1289-1293. PMID 8191282 DOI: 10.1126/Science.8191282 |
0.507 |
|
| 1994 |
Janda KD, Lo CHL, Li T, Barbas CF, Wirsching P, Lerner RA. Direct selection for a catalytic mechanism from combinatorial antibody libraries Proceedings of the National Academy of Sciences of the United States of America. 91: 2532-2536. PMID 8146149 DOI: 10.1073/Pnas.91.7.2532 |
0.512 |
|
| 1994 |
Erb E, Janda KD, Brenner S. Recursive deconvolution of combinatorial chemical libraries. Proceedings of the National Academy of Sciences of the United States of America. 91: 11422-6. PMID 7972077 DOI: 10.1073/Pnas.91.24.11422 |
0.311 |
|
| 1994 |
Yli-Kauhaluoma J, Janda KD. Twisted α-keto amides as transition-state analogues for acyl-transfer reactions: Synthesis of the immunoconjugates Bioorganic and Medicinal Chemistry. 2: 521-528. PMID 7528089 DOI: 10.1016/0968-0896(94)80022-7 |
0.57 |
|
| 1994 |
Janda KD. Catalytic antibodies and enzyme inhibitors Pure and Applied Chemistry. 66: 703-708. DOI: 10.1351/Pac199466040703 |
0.338 |
|
| 1994 |
Cravatt BF, Ashley JA, Janda KD, Boger DL, Lerner RA. Crossing Extreme Mechanistic Barriers by Antibody Catalysis: Syn Elimination to a Cis Olefin Journal of the American Chemical Society. 116: 6013-6014. DOI: 10.1021/Ja00092A080 |
0.581 |
|
| 1994 |
Shevlin CG, Hilton S, Janda KD. Automation of antibody catalysis: a practical methodology for the use of catalytic antibodies in organic synthesis Bioorganic & Medicinal Chemistry Letters. 4: 297-302. DOI: 10.1016/S0960-894X(01)80132-3 |
0.343 |
|
| 1994 |
Yli-Kauhaluoma JT, Janda KD. An expedient synthesis of isopropyl anisoles and veratroles Tetrahedron Letters. 35: 4509-4510. DOI: 10.1016/S0040-4039(00)60713-X |
0.516 |
|
| 1994 |
Janda KD, Jack CY-. Chemical and Biological Approaches to Catalytic Antibodies Handbook of Experimental Pharmacology. 113: 209-241. DOI: 10.1007/978-3-642-78432-3_9 |
0.308 |
|
| 1994 |
Nielsen J, Janda KD. Toward Chemical Implementation of Encoded Combinatorial Libraries Methods. 6: 361-371. DOI: 10.1006/Meth.1994.1036 |
0.545 |
|
| 1993 |
Janda KD, Shevlin CG, Lerner RA. Antibody catalysis of a disfavored chemical transformation Science. 259: 490-493. PMID 8424171 DOI: 10.1126/Science.8424171 |
0.512 |
|
| 1993 |
Gouverneur VE, Houk KN, de Pascual-Teresa B, Beno B, Janda KD, Lerner RA. Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis. Science (New York, N.Y.). 262: 204-8. PMID 8211138 DOI: 10.1126/Science.8211138 |
0.635 |
|
| 1993 |
Janda KD. Catalytic antibodies: The rerouting of chemical reactions Biochemical Society Transactions. 21: 1090-1095. PMID 8131905 DOI: 10.1042/Bst0211090 |
0.32 |
|
| 1993 |
IKEDA S, Janda KD. Recent Development on the Research of Catalytic Antibodies and Their Applications. Journal of Synthetic Organic Chemistry, Japan. 51: 284-297. DOI: 10.5059/Yukigoseikyokaishi.51.284 |
0.34 |
|
| 1993 |
Nielsen J, Brenner S, Janda KD. Synthetic methods for the implementation of encoded combinatorial chemistry Journal of the American Chemical Society. 115: 9812-9813. DOI: 10.1021/Ja00074A063 |
0.507 |
|
| 1993 |
Na J, Houk KN, Shevlin CG, Janda KD, Lerner RA. The energetic advantage of 5-exo versus 6-endo epoxide openings: a preference overwhelmed by antibody catalysis Journal of the American Chemical Society. 115: 8453-8454. DOI: 10.1021/Ja00071A067 |
0.51 |
|
| 1993 |
Wade WS, Ashley JA, Jahangiri GK, McElhaney G, Janda KD, Lerner RA. A highly specific metal-activated catalytic antibody Journal of the American Chemical Society. 115: 4906-4907. DOI: 10.1021/Ja00064A068 |
0.492 |
|
| 1993 |
Ashley JA, Lo CHL, McElhaney GP, Wirsching P, Janda KD. Catalytic antibody model for PLP-dependent decarboxylases Journal of the American Chemical Society. 115: 2515-2516. DOI: 10.1021/Ja00059A061 |
0.314 |
|
| 1993 |
Jack Chen YC, Danon T, Sastry L, Mubaraki M, Janda KD, Lerner RA. Catalytic antibodies from combinatorial libraries Journal of the American Chemical Society. 115: 357-358. DOI: 10.1021/Ja00054A058 |
0.741 |
|
| 1992 |
Benkovic SJ, Adams J, Janda KD, Lerner RA. A catalytic antibody uses a multistep kinetic sequence. Ciba Foundation Symposium. 159: 4-9; discussion 9-12. PMID 1959451 DOI: 10.1002/9780470514108.ch2 |
0.405 |
|
| 1992 |
Hein MB, Tang Y, McLeod DA, Janda KD, Hiatt A. Evaluation of immunoglobulins from plant cells. Biotechnology Progress. 7: 455-61. PMID 1367994 DOI: 10.1021/Bp00011A011 |
0.317 |
|
| 1992 |
Fernholz E, Schloeder D, Liu KKC, Bradshaw CW, Huang H, Janda K, Lerner RA, Wong CH. Specificity of antibody-catalyzed transesterifications using enol esters: A comparison with lipase reactions Journal of Organic Chemistry. 57: 4756-4761. DOI: 10.1021/Jo00043A042 |
0.509 |
|
| 1992 |
Gibbs RA, Benkovic PA, Janda KD, Lerner RA, Benkovic SJ. Substituent effects of an antibody-catalyzed hydrolysis of phenyl esters: further evidence for an acyl-antibody intermediate Journal of the American Chemical Society. 114: 3528-3534. DOI: 10.1021/Ja00035A057 |
0.507 |
|
| 1992 |
Reymond JL, Janda KD, Lerner RA. Highly enantioselective protonation catalyzed by an antibody Journal of the American Chemical Society. 114: 2257-2258. DOI: 10.1021/Ja00032A050 |
0.509 |
|
| 1991 |
Wirsching P, Ashley JA, Benkovic SJ, Janda KD, Lerner RA. An unexpectedly efficient catalytic antibody operating by ping-pong and induced fit mechanisms. Science (New York, N.Y.). 252: 680-5. PMID 2024120 DOI: 10.1126/Science.2024120 |
0.532 |
|
| 1991 |
Kang AS, Barbas CF, Janda KD, Benkovic SJ, Lerner RA. Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces. Proceedings of the National Academy of Sciences of the United States of America. 88: 4363-6. PMID 1903540 DOI: 10.1073/Pnas.88.10.4363 |
0.511 |
|
| 1991 |
Sastry L, Mubaraki M, Janda KD, Benkovic SJ, Lerner RA. Screening combinatorial antibody libraries for catalytic acyl transfer reactions. Ciba Foundation Symposium. 159: 145-51; discussion 1. PMID 1835693 DOI: 10.1002/9780470514108.ch10 |
0.724 |
|
| 1991 |
Fujii I, Lerner RA, Janda KD. Enantiofacial protonation by catalytic antibodies Journal of the American Chemical Society. 113: 8528-8529. DOI: 10.1021/Ja00022A054 |
0.5 |
|
| 1991 |
Ikeda S, Weinhouse MI, Janda KD, Lerner RA, Danishefsky SJ. Asymmetric induction via a catalytic antibody Journal of the American Chemical Society. 113: 7763-7764. DOI: 10.1021/Ja00020A049 |
0.513 |
|
| 1991 |
Janda KD, Weinhouse MI, Danon T, Pacelli KA, Schloeder DM. Antibody bait and switch catalysis: a survey of antigens capable of inducing abzymes with acyl-transfer properties Journal of the American Chemical Society. 113: 5427-5434. DOI: 10.1021/Ja00014A039 |
0.304 |
|
| 1991 |
Janda KD, Ashley JA, Jones TM, McLeod DA, Schloeder DM, Weinhouse MI, Lerner RA, Gibbs RA, Benkovic PA. Catalytic antibodies with acyl-transfer capabilities: mechanistic and kinetic investigations Journal of the American Chemical Society. 113: 291-297. DOI: 10.1021/Ja00001A042 |
0.503 |
|
| 1991 |
Janda KD, Benkovic SJ, McLeod DA, Schloeder DM, Lerner RA. Substrate attenuation: An approach to improve antibody catalysis Tetrahedron. 47: 2503-2506. DOI: 10.1016/S0040-4020(01)81784-1 |
0.519 |
|
| 1991 |
Reymond J, Janda KD, Lerner RA. Antibody Catalysis of Glycosidic Bond Hydrolysis Angewandte Chemie International Edition in English. 30: 1711-1713. DOI: 10.1002/Anie.199117111 |
0.486 |
|
| 1991 |
Reymond J, Janda KD, Lerner RA. Antikörper-katalysierte Hydrolyse glycosidischer Bindungen Angewandte Chemie. 103: 1690-1692. DOI: 10.1002/Ange.19911031226 |
0.417 |
|
| 1990 |
Benkovic SJ, Adams JA, Borders CL, Janda KD, Lerner RA. The enzymic nature of antibody catalysis: development of multistep kinetic processing. Science (New York, N.Y.). 250: 1135-9. PMID 2251500 DOI: 10.1126/Science.2251500 |
0.525 |
|
| 1990 |
Janda KD. New strategies for the design of catalytic antibodies Biotechnology Progress. 6: 178-181. PMID 1366610 DOI: 10.1021/Bp00003A002 |
0.328 |
|
| 1990 |
Janda KD, Ashley JA, Jones TM, McLeod DA, Schloeder DM, Weinhouse MI. Immobilized catalytic antibodies in aqueous and organic solvents Journal of the American Chemical Society. 112: 8886-8888. DOI: 10.1021/Ja00180A035 |
0.301 |
|
| 1990 |
Janda KD, Weinhouse MI, Schloeder DM, Lerner RA, Benkovic SJ. Bait and switch strategy for obtaining catalytic antibodies with acyl-transfer capabilities Journal of the American Chemical Society. 112: 1274-1275. DOI: 10.1021/Ja00159A074 |
0.493 |
|
| 1989 |
Janda KD, Benkovic SJ, Lerner RA. Catalytic antibodies with lipase activity and R or S substrate selectivity. Science (New York, N.Y.). 244: 437-40. PMID 2717936 DOI: 10.1126/Science.2717936 |
0.499 |
|
| 1989 |
Sastry L, Alting-Mees M, Huse WD, Short JM, Sorge JA, Hay BN, Janda KD, Benkovic SJ, Lerner RA. Cloning of the immunological repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: construction of a heavy chain variable region-specific cDNA library. Proceedings of the National Academy of Sciences of the United States of America. 86: 5728-32. PMID 2503822 DOI: 10.1073/Pnas.86.15.5728 |
0.745 |
|
| 1988 |
Janda KD, Schloeder D, Benkovic SJ, Lerner RA. Induction of an antibody that catalyzes the hydrolysis of an amide bond. Science (New York, N.Y.). 241: 1188-91. PMID 3413482 DOI: 10.1126/Science.3413482 |
0.509 |
|
| 1988 |
Janda KD, Lerner RA, Tramontano A. Antibody catalysis of bimolecular amide formation Journal of the American Chemical Society. 110: 4835-4837. DOI: 10.1021/Ja00222A056 |
0.439 |
|
| 1988 |
JANDA KD, LERNER RA, TRAMONTANO A. ChemInform Abstract: Antibody Catalysis of Bimolecular Amide Formation. Cheminform. 19. DOI: 10.1002/chin.198845122 |
0.443 |
|
| 1986 |
Tramontano A, Janda KD, Lerner RA. Chemical reactivity at an antibody binding site elicited by mechanistic design of a synthetic antigen. Proceedings of the National Academy of Sciences of the United States of America. 83: 6736-40. PMID 3462723 DOI: 10.1073/Pnas.83.18.6736 |
0.537 |
|
| 1985 |
Bates RB, Janda KD, Wright ME. N-Isobutyrylbenzamide, C11H13NO2 Acta Crystallographica Section C Crystal Structure Communications. 41: 263-264. DOI: 10.1107/S0108270185003559 |
0.444 |
|
| 1985 |
BATES RB, FLETCHER FA, JANDA KD, MILLER WA. ChemInform Abstract: A CONVENIENT SYNTHESIS OF UNSYMMETRICAL ACYCLIC IMIDES Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198502163 |
0.413 |
|
| 1984 |
Bates RB, Janda KD. A Convenient Synthesis of α-Acylamino Alcohols from Azlactones Synthesis. 1984: 310-311. DOI: 10.1055/S-1984-30820 |
0.458 |
|
| 1984 |
Bates RB, Fletcher FA, Janda KD, Miller WA. A convenient synthesis of unsymmetrical acyclic imides The Journal of Organic Chemistry. 49: 3038-3038. DOI: 10.1002/Chin.198502163 |
0.481 |
|
| 1984 |
BATES RB, GIN SL, HASSEN MA, HRUBY VJ, JANDA KD, KRIEK GR, MICHAUD J, VINE DB. ChemInform Abstract: SYNTHESIS OF CYCLO-N-METHYL-L-TYR-N-METHYL-L-TYR-D-ALA-L-ALA-O,N-DIMETHYL-L-TYR-L-ALA, A CYCLIC HEXAPEPTIDE RELATED TO THE ANTITUMOR AGENT DEOXYBOUVARDIN Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198440222 |
0.539 |
|
| 1984 |
BATES RB, JANDA KD. ChemInform Abstract: A CONVENIENT SYNTHESIS OF α-ACYLAMINO ALCOHOLS FROM AZLACTONES Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198436151 |
0.391 |
|
| 1983 |
BATES RB, JANDA KD. ChemInform Abstract: HIGH-YIELD BENZYNE SYNTHESIS OF DIARYL ETHERS Chemischer Informationsdienst. 14. DOI: 10.1002/CHIN.198311133 |
0.414 |
|
| 1982 |
Bates RB, Janda KD. High-yield benzyne synthesis of diaryl ethers The Journal of Organic Chemistry. 47: 4374-4376. DOI: 10.1021/Jo00143A051 |
0.482 |
|
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