Alice Prince - Publications

Columbia University, New York, NY 
Immunology, Pharmacology, Microbiology Biology, Cell Biology

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Hook JL, Islam MN, Parker D, Prince AS, Bhattacharya S, Bhattacharya J. Disruption of staphylococcal aggregation protects against lethal lung injury. The Journal of Clinical Investigation. PMID 29431734 DOI: 10.1172/JCI95823  0.56
2017 Wickersham M, Wachtel S, Wong Fok Lung T, Soong G, Jacquet R, Richardson A, Parker D, Prince A. Metabolic Stress Drives Keratinocyte Defenses against Staphylococcus aureus Infection. Cell Reports. 18: 2742-2751. PMID 28297676 DOI: 10.1016/j.celrep.2017.02.055  0.56
2016 Ahn D, Peñaloza H, Wang Z, Wickersham M, Parker D, Patel P, Koller A, Chen EI, Bueno SM, Uhlemann AC, Prince A. Acquired resistance to innate immune clearance promotes Klebsiella pneumoniae ST258 pulmonary infection. Jci Insight. 1: e89704. PMID 27777978 DOI: 10.1172/jci.insight.89704  0.56
2016 Parker D, Prince A. Immunoregulatory effects of necroptosis in bacterial infections. Cytokine. 88: 274-275. PMID 27710879 DOI: 10.1016/j.cyto.2016.09.024  0.56
2016 Prince A, Wang H, Kitur K, Parker D. Humanized mice exhibit increased susceptibility to Staphylococcus aureus pneumonia. The Journal of Infectious Diseases. PMID 27638942 DOI: 10.1093/infdis/jiw425  0.56
2016 Kitur K, Wachtel S, Brown A, Wickersham M, Paulino F, Peñaloza HF, Soong G, Bueno S, Parker D, Prince A. Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling. Cell Reports. PMID 27524612 DOI: 10.1016/j.celrep.2016.07.039  0.96
2016 Parker D, Prince A. A new approach to toxin neutralization in Staphylococcus aureus therapy. Embo Reports. 17: 284-5. PMID 26882555 DOI: 10.15252/embr.201642015  0.56
2016 Planet PJ, Parker D, Cohen TS, Smith H, Leon JD, Ryan C, Hammer TJ, Fierer N, Chen EI, Prince AS. Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection. Mbio. 7. PMID 26861017 DOI: 10.1128/mBio.01939-15  0.96
2016 Parker D, Ahn D, Cohen T, Prince A. Innate Immune Signaling Activated by MDR Bacteria in the Airway. Physiological Reviews. 96: 19-53. PMID 26582515 DOI: 10.1152/physrev.00009.2015  0.96
2015 Soong G, Paulino F, Wachtel S, Parker D, Wickersham M, Zhang D, Brown A, Lauren C, Dowd M, West E, Horst B, Planet P, Prince A. Methicillin-resistant Staphylococcus aureus adaptation to human keratinocytes. Mbio. 6. PMID 25900653 DOI: 10.1128/mBio.00289-15  0.96
2015 Kitur K, Parker D, Nieto P, Ahn DS, Cohen TS, Chung S, Wachtel S, Bueno S, Prince A. Toxin-induced necroptosis is a major mechanism of Staphylococcus aureus lung damage. Plos Pathogens. 11: e1004820. PMID 25880560 DOI: 10.1371/journal.ppat.1004820  0.96
2015 Amaral FE, Parker D, Randis TM, Kulkarni R, Prince AS, Shirasu-Hiza MM, Ratner AJ. Rational manipulation of mRNA folding free energy allows rheostat control of pneumolysin production by Streptococcus pneumoniae. Plos One. 10: e0119823. PMID 25798590 DOI: 10.1371/journal.pone.0119823  0.56
2015 Parker D, Ryan CL, Alonzo F, Torres VJ, Planet PJ, Prince AS. CD4+ T cells promote the pathogenesis of Staphylococcus aureus pneumonia. The Journal of Infectious Diseases. 211: 835-45. PMID 25240171 DOI: 10.1093/infdis/jiu525  0.96
2015 Parker D, Planet P, Cohen T, Smith H, Leon J, Ryan C, Hammer T, Fierer N, Cheng E, Prince A. ID: 248 Cytokine. 76: 111. DOI: 10.1016/j.cyto.2015.08.251  0.56
2014 Parker D, Narechania A, Sebra R, Deikus G, Larussa S, Ryan C, Smith H, Prince A, Mathema B, Ratner AJ, Kreiswirth B, Planet PJ. Genome Sequence of Bacterial Interference Strain Staphylococcus aureus 502A. Genome Announcements. 2. PMID 24723721 DOI: 10.1128/genomeA.00284-14  0.56
2014 Parker D, Planet PJ, Soong G, Narechania A, Prince A. Induction of type I interferon signaling determines the relative pathogenicity of Staphylococcus aureus strains. Plos Pathogens. 10: e1003951. PMID 24586160 DOI: 10.1371/journal.ppat.1003951  0.96
2014 Westphalen K, Gusarova GA, Islam MN, Subramanian M, Cohen TS, Prince AS, Bhattacharya J. Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity. Nature. 506: 503-6. PMID 24463523 DOI: 10.1038/nature12902  0.96
2013 Planet PJ, LaRussa SJ, Dana A, Smith H, Xu A, Ryan C, Uhlemann AC, Boundy S, Goldberg J, Narechania A, Kulkarni R, Ratner AJ, Geoghegan JA, Kolokotronis SO, Prince A. Emergence of the epidemic methicillin-resistant Staphylococcus aureus strain USA300 coincides with horizontal transfer of the arginine catabolic mobile element and speG-mediated adaptations for survival on skin. Mbio. 4: e00889-13. PMID 24345744 DOI: 10.1128/mBio.00889-13  0.96
2013 Cohen TS, Prince AS. Bacterial pathogens activate a common inflammatory pathway through IFNλ regulation of PDCD4. Plos Pathogens. 9: e1003682. PMID 24098127 DOI: 10.1371/journal.ppat.1003682  0.96
2013 Parker D, Prince A. Epithelial uptake of flagella initiates proinflammatory signaling. Plos One. 8: e59932. PMID 23527288 DOI: 10.1371/journal.pone.0059932  0.96
2013 Cohen TS, Prince AS. Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia. The Journal of Clinical Investigation. 123: 1630-7. PMID 23478406 DOI: 10.1172/JCI66142  0.96
2012 Recinos DA, Sekedat MD, Hernandez A, Cohen TS, Sakhtah H, Prince AS, Price-Whelan A, Dietrich LE. Redundant phenazine operons in Pseudomonas aeruginosa exhibit environment-dependent expression and differential roles in pathogenicity. Proceedings of the National Academy of Sciences of the United States of America. 109: 19420-5. PMID 23129634 DOI: 10.1073/pnas.1213901109  0.96
2012 Prince A. The bitter taste of infection. The Journal of Clinical Investigation. 122: 3847-9. PMID 23041625 DOI: 10.1172/JCI66182  0.96
2012 Parker D, Prince A. Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9. Journal of Immunology (Baltimore, Md. : 1950). 189: 4040-6. PMID 22962685 DOI: 10.4049/jimmunol.1201055  0.96
2012 Garofalo A, Giai C, Lattar S, Gardella N, Mollerach M, Kahl BC, Becker K, Prince AS, Sordelli DO, Gómez MI. The length of the Staphylococcus aureus protein A polymorphic region regulates inflammation: impact on acute and chronic infection. The Journal of Infectious Diseases. 206: 81-90. PMID 22535996 DOI: 10.1093/infdis/jis311  0.96
2012 Cohen TS, Prince A. Cystic fibrosis: a mucosal immunodeficiency syndrome. Nature Medicine. 18: 509-19. PMID 22481418 DOI: 10.1038/nm.2715  0.96
2012 Soong G, Chun J, Parker D, Prince A. Staphylococcus aureus activation of caspase 1/calpain signaling mediates invasion through human keratinocytes. The Journal of Infectious Diseases. 205: 1571-9. PMID 22457275 DOI: 10.1093/infdis/jis244  0.96
2012 Parker D, Prince A. Immunopathogenesis of Staphylococcus aureus pulmonary infection. Seminars in Immunopathology. 34: 281-97. PMID 22037948 DOI: 10.1007/s00281-011-0291-7  0.56
2012 Parker D, Cohen TS, Alhede M, Harfenist BS, Martin FJ, Prince A. Induction of type I interferon signaling by Pseudomonas aeruginosa is diminished in cystic fibrosis epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 46: 6-13. PMID 21778412 DOI: 10.1165/rcmb.2011-0080OC  0.96
2011 Parker D, Prince A. Type I interferon response to extracellular bacteria in the airway epithelium. Trends in Immunology. 32: 582-8. PMID 21996313 DOI: 10.1016/  0.56
2011 Soong G, Martin FJ, Chun J, Cohen TS, Ahn DS, Prince A. Staphylococcus aureus protein A mediates invasion across airway epithelial cells through activation of RhoA GTPase signaling and proteolytic activity. The Journal of Biological Chemistry. 286: 35891-8. PMID 21878647 DOI: 10.1074/jbc.M111.295386  0.96
2011 Parker D, Martin FJ, Soong G, Harfenist BS, Aguilar JL, Ratner AJ, Fitzgerald KA, Schindler C, Prince A. Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract. Mbio. 2: e00016-11. PMID 21586648 DOI: 10.1128/mBio.00016-11  0.92
2011 Martin FJ, Parker D, Harfenist BS, Soong G, Prince A. Participation of CD11c(+) leukocytes in methicillin-resistant Staphylococcus aureus clearance from the lung. Infection and Immunity. 79: 1898-904. PMID 21402768 DOI: 10.1128/IAI.01299-10  0.92
2011 Parker D, Prince A. Innate immunity in the respiratory epithelium. American Journal of Respiratory Cell and Molecular Biology. 45: 189-201. PMID 21330463 DOI: 10.1165/rcmb.2011-0011RT  0.56
2010 Lee MH, Arrecubieta C, Martin FJ, Prince A, Borczuk AC, Lowy FD. A postinfluenza model of Staphylococcus aureus pneumonia. The Journal of Infectious Diseases. 201: 508-15. PMID 20078212 DOI: 10.1086/650204  0.92
2009 Chun J, Prince A. Ca2+ signaling in airway epithelial cells facilitates leukocyte recruitment and transepithelial migration. Journal of Leukocyte Biology. 86: 1135-44. PMID 19605699 DOI: 10.1189/jlb.0209072  1
2009 Martin FJ, Gomez MI, Wetzel DM, Memmi G, O'Seaghdha M, Soong G, Schindler C, Prince A. Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A. The Journal of Clinical Investigation. 119: 1931-9. PMID 19603548 DOI: 10.1172/JCI35879  0.96
2009 Parker D, Soong G, Planet P, Brower J, Ratner AJ, Prince A. The NanA neuraminidase of Streptococcus pneumoniae is involved in biofilm formation. Infection and Immunity. 77: 3722-30. PMID 19564377 DOI: 10.1128/IAI.00228-09  0.56
2009 Hsiao YS, Parker D, Ratner AJ, Prince A, Tong L. Crystal structures of respiratory pathogen neuraminidases. Biochemical and Biophysical Research Communications. 380: 467-71. PMID 19284989 DOI: 10.1016/j.bbrc.2009.01.108  0.96
2009 Chun J, Prince A. TLR2-induced calpain cleavage of epithelial junctional proteins facilitates leukocyte transmigration. Cell Host & Microbe. 5: 47-58. PMID 19154987 DOI: 10.1016/j.chom.2008.11.009  0.96
2008 Martin FJ, Prince AS. TLR2 regulates gap junction intercellular communication in airway cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 4986-93. PMID 18354224  0.96
2008 Soong G, Parker D, Magargee M, Prince AS. The type III toxins of Pseudomonas aeruginosa disrupt epithelial barrier function. Journal of Bacteriology. 190: 2814-21. PMID 18165298 DOI: 10.1128/JB.01567-07  0.56
2007 Waters VJ, Gómez MI, Soong G, Amin S, Ernst RK, Prince A. Immunostimulatory properties of the emerging pathogen Stenotrophomonas maltophilia. Infection and Immunity. 75: 1698-703. PMID 17220304 DOI: 10.1128/IAI.01469-06  0.56
2006 Soong G, Muir A, Gomez MI, Waks J, Reddy B, Planet P, Singh PK, Kaneko Y, Kanetko Y, Wolfgang MC, Hsiao YS, Tong L, Prince A. Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production. The Journal of Clinical Investigation. 116: 2297-2305. PMID 16862214 DOI: 10.1172/JCI27920  0.96
2006 Chun J, Prince A. Activation of Ca2+-dependent signaling by TLR2. Journal of Immunology (Baltimore, Md. : 1950). 177: 1330-7. PMID 16818794 DOI: 10.4049/jimmunol.177.2.1330  1
2006 Gómez MI, O'Seaghdha M, Magargee M, Foster TJ, Prince AS. Staphylococcus aureus protein A activates TNFR1 signaling through conserved IgG binding domains. The Journal of Biological Chemistry. 281: 20190-6. PMID 16709567 DOI: 10.1074/jbc.M601956200  0.96
2005 Wagner T, Soong G, Sokol S, Saiman L, Prince A. Effects of azithromycin on clinical isolates of Pseudomonas aeruginosa from cystic fibrosis patients. Chest. 128: 912-9. PMID 16100186 DOI: 10.1378/chest.128.2.912  0.96
2005 Gómez MI, Sokol SH, Muir AB, Soong G, Bastien J, Prince AS. Bacterial induction of TNF-alpha converting enzyme expression and IL-6 receptor alpha shedding regulates airway inflammatory signaling. Journal of Immunology (Baltimore, Md. : 1950). 175: 1930-6. PMID 16034137 DOI: 10.4049/jimmunol.175.3.1930  0.96
2005 Waters V, Sokol S, Reddy B, Soong G, Chun J, Prince A. The effect of cyclosporin A on airway cell proinflammatory signaling and pneumonia. American Journal of Respiratory Cell and Molecular Biology. 33: 138-44. PMID 15879161 DOI: 10.1165/rcmb.2005-0005OC  0.96
2004 Gómez MI, Lee A, Reddy B, Muir A, Soong G, Pitt A, Cheung A, Prince A. Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1. Nature Medicine. 10: 842-8. PMID 15247912 DOI: 10.1038/nm1079  0.56
2004 Soong G, Reddy B, Sokol S, Adamo R, Prince A. TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells. The Journal of Clinical Investigation. 113: 1482-9. PMID 15146246 DOI: 10.1172/JCI20773  0.96
2004 Muir A, Soong G, Sokol S, Reddy B, Gomez MI, Van Heeckeren A, Prince A. Toll-like receptors in normal and cystic fibrosis airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 30: 777-83. PMID 14656745 DOI: 10.1165/rcmb.2003-0329OC  0.96
2004 Adamo R, Sokol S, Soong G, Gomez MI, Prince A. Pseudomonas aeruginosa flagella activate airway epithelial cells through asialoGM1 and toll-like receptor 2 as well as toll-like receptor 5. American Journal of Respiratory Cell and Molecular Biology. 30: 627-34. PMID 14607814 DOI: 10.1165/rcmb.2003-0260OC  0.96
2002 Saba S, Soong G, Greenberg S, Prince A. Bacterial stimulation of epithelial G-CSF and GM-CSF expression promotes PMN survival in CF airways. American Journal of Respiratory Cell and Molecular Biology. 27: 561-7. PMID 12397015 DOI: 10.1165/rcmb.2002-0019OC  0.56
2002 Heyer G, Saba S, Adamo R, Rush W, Soong G, Cheung A, Prince A. Staphylococcus aureus agr and sarA functions are required for invasive infection but not inflammatory responses in the lung. Infection and Immunity. 70: 127-33. PMID 11748173 DOI: 10.1128/IAI.70.1.127-133.2002  0.56
2001 Rastogi D, Ratner AJ, Prince A. Host-bacterial interactions in the initiation of inflammation. Paediatric Respiratory Reviews. 2: 245-52. PMID 12052326 DOI: 10.1053/prrv.2001.0147  0.96
2001 Weber AJ, Soong G, Bryan R, Saba S, Prince A. Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L71-8. PMID 11404248 DOI: 10.1152/ajplung.2001.281.1.L71  0.56
2000 Pearson JP, Feldman M, Iglewski BH, Prince A. Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infection Infection and Immunity. 68: 4331-4334. PMID 10858254 DOI: 10.1128/IAI.68.7.4331-4334.2000  0.96
1999 Worgall S, Bezdicek P, Kim MK, Park JG, Singh R, Christofidou-Solomidou M, Prince A, Kovesdi I, Schreiber AD, Crystal RG. Augmentation of pulmonary host defense against Pseudomonas by FcgammaRIIA cDNA transfer to the respiratory epithelium. The Journal of Clinical Investigation. 104: 409-18. PMID 10449433 DOI: 10.1172/JCI5432  0.96
1999 Bryan R, Feldman M, Jawetz SC, Rajan S, DiMango E, Tang HB, Scheffler L, Speert DP, Prince A. The effects of aerosolized dextran in a mouse model of Pseudomonas aeruginosa pulmonary infection Journal of Infectious Diseases. 179: 1449-1458. PMID 10228067 DOI: 10.1086/314755  0.96
1995 Imundo L, Barasch J, Prince A, Al-Awqati Q. Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface Proceedings of the National Academy of Sciences of the United States of America. 92: 3019-3023. PMID 7708767 DOI: 10.1073/pnas.92.7.3019  0.96
1995 Zar H, Saiman L, Quittell L, Prince A. Binding of Pseudomonas aeruginosa to respiratory epithelial cells from patients with various mutations in the cystic fibrosis transmembrane regulator. The Journal of Pediatrics. 126: 230-3. PMID 7531240 DOI: 10.1016/S0022-3476(95)70549-X  0.96
1990 Saiman L, Ishimoto K, Lory S, Prince A. The effect of piliation and exoproduct expression on the adherence of Pseudomonas aeruginosa to respiratory epithelial monolayers Journal of Infectious Diseases. 161: 541-548. PMID 1968936 DOI: 10.1093/infdis/161.3.541  0.96
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