Akiko Iwasaki - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Immunology, Microbiology Biology, Virology Biology

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Amezcua Vesely MC, Pallis P, Bielecki P, Low JS, Zhao J, Harman CCD, Kroehling L, Jackson R, Bailis W, Licona-Limón P, Xu H, Iijima N, Pillai PS, Kaplan DH, Weaver CT, ... ... Iwasaki A, et al. Effector T17 Cells Give Rise to Long-Lived T Cells that Are Essential for an Immediate Response against Bacterial Infection. Cell. 178: 1176-1188.e15. PMID 31442406 DOI: 10.1016/j.cell.2019.07.032  1
2019 Treger RS, Tokuyama M, Dong H, Salas-Briceno K, Ross SR, Kong Y, Iwasaki A. Human APOBEC3G prevents emergence of infectious endogenous retrovirus in mice. Journal of Virology. PMID 31341050 DOI: 10.1128/JVI.00728-19  1
2019 Oh JE, Iijima N, Song E, Lu P, Klein J, Jiang R, Kleinstein SH, Iwasaki A. Migrant memory B cells secrete luminal antibody in the vagina. Nature. PMID 31189952 DOI: 10.1038/s41586-019-1285-1  1
2019 Ren X, Linehan MM, Iwasaki A, Pyle AM. RIG-I Selectively Discriminates against 5'-Monophosphate RNA. Cell Reports. 26: 2019-2027.e4. PMID 30784585 DOI: 10.1016/j.celrep.2019.01.107  1
2019 Treger RS, Pope SD, Kong Y, Tokuyama M, Taura M, Iwasaki A. The Lupus Susceptibility Locus Sgp3 Encodes the Suppressor of Endogenous Retrovirus Expression SNERV. Immunity. PMID 30709743 DOI: 10.1016/j.immuni.2018.12.022  1
2018 Tokuyama M, Kong Y, Song E, Jayewickreme T, Kang I, Iwasaki A. ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses. Proceedings of the National Academy of Sciences of the United States of America. PMID 30455304 DOI: 10.1073/pnas.1814589115  1
2018 Mihaylova VT, Kong Y, Fedorova O, Sharma L, Dela Cruz CS, Pyle AM, Iwasaki A, Foxman EF. Regional Differences in Airway Epithelial Cells Reveal Tradeoff between Defense against Oxidative Stress and Defense against Rhinovirus. Cell Reports. 24: 3000-3007.e3. PMID 30208323 DOI: 10.1016/j.celrep.2018.08.033  1
2018 Orzalli MH, Smith A, Jurado KA, Iwasaki A, Garlick JA, Kagan JC. An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication. Molecular Cell. PMID 30100266 DOI: 10.1016/j.molcel.2018.07.009  1
2018 Wu L, Cao J, Cai WL, Lang SM, Horton JR, Jansen DJ, Liu ZZ, Chen JF, Zhang M, Mott BT, Pohida K, Rai G, Kales SC, Henderson MJ, Hu X, ... ... Iwasaki A, et al. KDM5 histone demethylases repress immune response via suppression of STING. Plos Biology. 16: e2006134. PMID 30080846 DOI: 10.1371/journal.pbio.2006134  1
2018 Hayashi K, Taura M, Iwasaki A. The interaction between IKKα and LC3 promotes type I interferon production through the TLR9-containing LAPosome. Science Signaling. 11. PMID 29717061 DOI: 10.1126/scisignal.aan4144  1
2018 Linehan MM, Dickey TH, Molinari ES, Fitzgerald ME, Potapova O, Iwasaki A, Pyle AM. A minimal RNA ligand for potent RIG-I activation in living mice. Science Advances. 4: e1701854. PMID 29492454 DOI: 10.1126/sciadv.1701854  1
2018 Yockey LJ, Jurado KA, Arora N, Millet A, Rakib T, Milano KM, Hastings AK, Fikrig E, Kong Y, Horvath TL, Weatherbee S, Kliman HJ, Coyne CB, Iwasaki A. Type I interferons instigate fetal demise after Zika virus infection. Science Immunology. 3. PMID 29305462 DOI: 10.1126/sciimmunol.aao1680  1
2017 Molony RD, Nguyen JT, Kong Y, Montgomery RR, Shaw AC, Iwasaki A. Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes. Science Signaling. 10. PMID 29233916 DOI: 10.1126/scisignal.aan2392  1
2017 Sasai M, Sakaguchi N, Ma JS, Nakamura S, Kawabata T, Bando H, Lee Y, Saitoh T, Akira S, Iwasaki A, Standley DM, Yoshimori T, Yamamoto M. Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense. Nature Immunology. PMID 28604719 DOI: 10.1038/ni.3767  1
2017 Uraki R, Jurado KA, Hwang J, Szigeti-Buck K, Horvath T, Iwasaki A, Fikrig E. Sexual transmission of ZIKV causes fetal growth restriction in mice. The Journal of Infectious Diseases. PMID 28472297 DOI: 10.1093/infdis/jix204  1
2017 Hastings AK, Yockey LJ, Jagger BW, Hwang J, Uraki R, Gaitsch HF, Parnell LA, Cao B, Mysorekar IU, Rothlin CV, Fikrig E, Diamond MS, Iwasaki A. TAM Receptors Are Not Required for Zika Virus Infection in Mice. Cell Reports. 19: 558-568. PMID 28423319 DOI: 10.1016/j.celrep.2017.03.058  1
2017 Goldberg EL, Asher JL, Molony RD, Shaw AC, Zeiss CJ, Wang C, Morozova-Roche LA, Herzog RI, Iwasaki A, Dixit VD. β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares. Cell Reports. 18: 2077-2087. PMID 28249154 DOI: 10.1016/j.celrep.2017.02.004  1
2016 Iwasaki A, Foxman EF, Molony RD. Early local immune defences in the respiratory tract. Nature Reviews. Immunology. PMID 27890913 DOI: 10.1038/nri.2016.117  1
2016 Shin H, Kumamoto Y, Gopinath S, Iwasaki A. CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2. Nature Communications. 7: 13346. PMID 27827367 DOI: 10.1038/ncomms13346  0.32
2016 Kumamoto Y, Hirai T, Wong PW, Kaplan DH, Iwasaki A. CD301b(+) dendritic cells suppress T follicular helper cells and antibody responses to protein antigens. Elife. 5. PMID 27657168 DOI: 10.7554/eLife.17979  1
2016 Kumamoto Y, Camporez JP, Jurczak MJ, Shanabrough M, Horvath T, Shulman GI, Iwasaki A. CD301b(+) Mononuclear Phagocytes Maintain Positive Energy Balance through Secretion of Resistin-like Molecule Alpha. Immunity. PMID 27566941 DOI: 10.1016/j.immuni.2016.08.002  0.32
2016 Yockey LJ, Varela L, Rakib T, Khoury-Hanold W, Fink SL, Stutz B, Szigeti-Buck K, Van den Pol A, Lindenbach BD, Horvath TL, Iwasaki A. Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection. Cell. 166: 1247-1256.e4. PMID 27565347 DOI: 10.1016/j.cell.2016.08.004  1
2016 Foxman EF, Storer JA, Vanaja K, Levchenko A, Iwasaki A. Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature. Proceedings of the National Academy of Sciences of the United States of America. PMID 27402752 DOI: 10.1073/pnas.1601942113  1
2016 Schmid ET, Pang IK, Carrera Silva EA, Bosurgi L, Miner JJ, Diamond MS, Iwasaki A, Rothlin CV. AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity. Elife. 5. PMID 27350258 DOI: 10.7554/eLife.12414  1
2016 Shook B, Xiao E, Kumamoto Y, Iwasaki A, Horsley V. CD301b+ macrophages are essential for effective skin wound healing. The Journal of Investigative Dermatology. PMID 27287183 DOI: 10.1016/j.jid.2016.05.107  0.32
2016 Khoury-Hanold W, Yordy B, Kong P, Kong Y, Ge W, Szigeti-Buck K, Ralevski A, Horvath TL, Iwasaki A. Viral Spread to Enteric Neurons Links Genital HSV-1 Infection to Toxic Megacolon and Lethality. Cell Host & Microbe. 19: 788-99. PMID 27281569 DOI: 10.1016/j.chom.2016.05.008  1
2016 Iijima N, Iwasaki A. Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help. Nature. 533: 552-6. PMID 27225131 DOI: 10.1038/nature17979  1
2016 Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, ... ... Iwasaki A, et al. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science (New York, N.Y.). 352: 463-6. PMID 27102485 DOI: 10.1126/science.aaf3926  1
2016 Gopinath S, Kumamoto Y, Iwasaki A. O-linked sugars sound the alarm. Nature Immunology. 17: 119-20. PMID 26784258 DOI: 10.1038/ni.3364  0.32
2016 Khoury-Hanold W, Iwasaki A. Autophagy Snuffs a Macrophage's Inner Fire. Cell Host & Microbe. 19: 9-11. PMID 26764592 DOI: 10.1016/j.chom.2015.12.015  1
2015 Iijima N, Iwasaki A. Tissue instruction for migration and retention of TRM cells. Trends in Immunology. 36: 556-64. PMID 26282885 DOI: 10.1016/j.it.2015.07.002  1
2015 Hayashi K, Sasai M, Iwasaki A. Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity. International Immunology. PMID 25925170 DOI: 10.1093/intimm/dxv021  1
2015 Iwasaki A, Medzhitov R. Control of adaptive immunity by the innate immune system. Nature Immunology. 16: 343-53. PMID 25789684 DOI: 10.1038/ni.3123  1
2015 Kashem SW, Igyártó BZ, Gerami-Nejad M, Kumamoto Y, Mohammed J, Jarrett E, Drummond RA, Zurawski SM, Zurawski G, Berman J, Iwasaki A, Brown GD, Kaplan DH. Candida albicans morphology and dendritic cell subsets determine T helper cell differentiation. Immunity. 42: 356-66. PMID 25680275 DOI: 10.1016/j.immuni.2015.01.008  1
2015 West AP, Khoury-Hanold W, Staron M, Tal MC, Pineda CM, Lang SM, Bestwick M, Duguay BA, Raimundo N, MacDuff DA, Kaech SM, Smiley JR, Means RE, Iwasaki A, Shadel GS. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 520: 553-7. PMID 25642965 DOI: 10.1038/nature14156  1
2015 Foxman EF, Storer JA, Fitzgerald ME, Wasik BR, Hou L, Zhao H, Turner PE, Pyle AM, Iwasaki A. Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 827-32. PMID 25561542 DOI: 10.1073/pnas.1411030112  1
2014 Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA. Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. Cell. 159: 1563-77. PMID 25525875 DOI: 10.1016/j.cell.2014.11.037  1
2014 Iijima N, Iwasaki A. T cell memory. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells. Science (New York, N.Y.). 346: 93-8. PMID 25170048 DOI: 10.1126/science.1257530  1
2014 Khan S, Toyoda H, Linehan M, Iwasaki A, Nomoto A, Bernhardt G, Cello J, Wimmer E. Poliomyelitis in transgenic mice expressing CD155 under the control of the Tage4 promoter after oral and parenteral poliovirus inoculation. The Journal of General Virology. 95: 1668-76. PMID 24784416 DOI: 10.1099/vir.0.064535-0  1
2014 Iwasaki A, Pillai PS. Innate immunity to influenza virus infection. Nature Reviews. Immunology. 14: 315-28. PMID 24762827 DOI: 10.1038/nri3665  0.64
2014 Guo YE, Riley KJ, Iwasaki A, Steitz JA. Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function. Molecular Cell. 54: 67-79. PMID 24725595 DOI: 10.1016/j.molcel.2014.03.025  1
2014 Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC. A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction. Cell. 156: 705-16. PMID 24529375 DOI: 10.1016/j.cell.2014.01.019  1
2014 Ding S, Khoury-Hanold W, Iwasaki A, Robek MD. Epigenetic reprogramming of the type III interferon response potentiates antiviral activity and suppresses tumor growth. Plos Biology. 12: e1001758. PMID 24409098 DOI: 10.1371/journal.pbio.1001758  1
2013 You F, Wang P, Yang L, Yang G, Zhao YO, Qian F, Walker W, Sutton R, Montgomery R, Lin R, Iwasaki A, Fikrig E. ELF4 is critical for induction of type I interferon and the host antiviral response. Nature Immunology. 14: 1237-46. PMID 24185615 DOI: 10.1038/ni.2756  1
2013 Kumamoto Y, Linehan M, Weinstein JS, Laidlaw BJ, Craft JE, Iwasaki A. CD301b⁺ dermal dendritic cells drive T helper 2 cell-mediated immunity. Immunity. 39: 733-43. PMID 24076051 DOI: 10.1016/j.immuni.2013.08.029  1
2013 Pang IK, Pillai PS, Iwasaki A. Efficient influenza A virus replication in the respiratory tract requires signals from TLR7 and RIG-I. Proceedings of the National Academy of Sciences of the United States of America. 110: 13910-5. PMID 23918369 DOI: 10.1073/pnas.1303275110  1
2013 Iijima N, Goodwin EC, Dimaio D, Iwasaki A. High-risk human papillomavirus E6 inhibits monocyte differentiation to Langerhans cells. Virology. 444: 257-62. PMID 23871219 DOI: 10.1016/j.virol.2013.06.020  1
2013 Mattei LM, Cotmore SF, Tattersall P, Iwasaki A. Parvovirus evades interferon-dependent viral control in primary mouse embryonic fibroblasts. Virology. 442: 20-7. PMID 23676303 DOI: 10.1016/j.virol.2013.03.020  1
2013 Sellers SL, Iwasaki A, Payne GW. Nitric oxide and TNFα are critical regulators of reversible lymph node vascular remodeling and adaptive immune response. Plos One. 8: e60741. PMID 23573281 DOI: 10.1371/journal.pone.0060741  1
2013 Hayashi K, Iwasaki A. Different routes to the same destination. Elife. 2: e00572. PMID 23426937 DOI: 10.7554/eLife.00572  1
2013 Pang IK, Ichinohe T, Iwasaki A. IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8⁺ T cell responses to influenza A virus. Nature Immunology. 14: 246-53. PMID 23314004 DOI: 10.1038/ni.2514  1
2013 Mattei LM, Cotmore SF, Li L, Tattersall P, Iwasaki A. Toll-like receptor 9 in plasmacytoid dendritic cells fails to detect parvoviruses. Journal of Virology. 87: 3605-8. PMID 23302877 DOI: 10.1128/JVI.03155-12  1
2013 Yordy B, Iwasaki A. Cell type-dependent requirement of autophagy in HSV-1 antiviral defense. Autophagy. 9: 236-8. PMID 23095715 DOI: 10.4161/auto.22506  1
2013 Yordy B, Tal MC, Hayashi K, Arojo O, Iwasaki A. Autophagy and selective deployment of Atg proteins in antiviral defense. International Immunology. 25: 1-10. PMID 23042773 DOI: 10.1093/intimm/dxs101  1
2012 Henault J, Martinez J, Riggs JM, Tian J, Mehta P, Clarke L, Sasai M, Latz E, Brinkmann MM, Iwasaki A, Coyle AJ, Kolbeck R, Green DR, Sanjuan MA. Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes. Immunity. 37: 986-97. PMID 23219390 DOI: 10.1016/j.immuni.2012.09.014  1
2012 Hoshi N, Schenten D, Nish SA, Walther Z, Gagliani N, Flavell RA, Reizis B, Shen Z, Fox JG, Iwasaki A, Medzhitov R. MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice. Nature Communications. 3: 1120. PMID 23047678 DOI: 10.1038/ncomms2113  1
2012 Yordy B, Iijima N, Huttner A, Leib D, Iwasaki A. A neuron-specific role for autophagy in antiviral defense against herpes simplex virus. Cell Host & Microbe. 12: 334-45. PMID 22980330 DOI: 10.1016/j.chom.2012.07.013  1
2012 Kumamoto Y, Iwasaki A. Unique features of antiviral immune system of the vaginal mucosa. Current Opinion in Immunology. 24: 411-6. PMID 22673876 DOI: 10.1016/j.coi.2012.05.006  0.32
2012 Kagan JC, Iwasaki A. Phagosome as the organelle linking innate and adaptive immunity. Traffic (Copenhagen, Denmark). 13: 1053-61. PMID 22577865 DOI: 10.1111/j.1600-0854.2012.01377.x  1
2012 Mantegazza AR, Guttentag SH, El-Benna J, Sasai M, Iwasaki A, Shen H, Laufer TM, Marks MS. Adaptor protein-3 in dendritic cells facilitates phagosomal toll-like receptor signaling and antigen presentation to CD4(+) T cells. Immunity. 36: 782-94. PMID 22560444 DOI: 10.1016/j.immuni.2012.02.018  1
2012 Pang IK, Iwasaki A. Control of antiviral immunity by pattern recognition and the microbiome. Immunological Reviews. 245: 209-26. PMID 22168422 DOI: 10.1111/j.1600-065X.2011.01073.x  1
2011 Yordy B, Iwasaki A. Autophagy in the control and pathogenesis of viral infection. Current Opinion in Virology. 1: 196-203. PMID 21927636 DOI: 10.1016/j.coviro.2011.05.016  1
2011 Iwasaki A, Medzhitov R. A new shield for a cytokine storm. Cell. 146: 861-2. PMID 21925310 DOI: 10.1016/j.cell.2011.08.027  1
2011 Tal MC, Iwasaki A. Mitoxosome: a mitochondrial platform for cross-talk between cellular stress and antiviral signaling. Immunological Reviews. 243: 215-34. PMID 21884179 DOI: 10.1111/j.1600-065X.2011.01038.x  1
2011 Sasai M, Iwasaki A. Love triangle between Unc93B1, TLR7, and TLR9 prevents fatal attraction. Immunity. 35: 3-5. PMID 21777792 DOI: 10.1016/j.immuni.2011.07.006  1
2011 Kumamoto Y, Mattei LM, Sellers S, Payne GW, Iwasaki A. CD4+ T cells support cytotoxic T lymphocyte priming by controlling lymph node input. Proceedings of the National Academy of Sciences of the United States of America. 108: 8749-54. PMID 21555577 DOI: 10.1073/pnas.1100567108  0.44
2011 Foxman EF, Iwasaki A. Genome-virome interactions: examining the role of common viral infections in complex disease. Nature Reviews. Microbiology. 9: 254-64. PMID 21407242 DOI: 10.1038/nrmicro2541  1
2011 Ichinohe T, Pang IK, Kumamoto Y, Peaper DR, Ho JH, Murray TS, Iwasaki A. Microbiota regulates immune defense against respiratory tract influenza A virus infection. Proceedings of the National Academy of Sciences of the United States of America. 108: 5354-9. PMID 21402903 DOI: 10.1073/pnas.1019378108  1
2011 Iijima N, Mattei LM, Iwasaki A. Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue. Proceedings of the National Academy of Sciences of the United States of America. 108: 284-9. PMID 21173243 DOI: 10.1073/pnas.1005201108  1
2011 Pang IK, Iwasaki A. Inflammasomes as mediators of immunity against influenza virus. Trends in Immunology. 32: 34-41. PMID 21147034 DOI: 10.1016/j.it.2010.11.004  1
2010 Sasai M, Linehan MM, Iwasaki A. Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3. Science (New York, N.Y.). 329: 1530-4. PMID 20847273 DOI: 10.1126/science.1187029  1
2010 Lindsay RW, Darrah PA, Quinn KM, Wille-Reece U, Mattei LM, Iwasaki A, Kasturi SP, Pulendran B, Gall JG, Spies AG, Seder RA. CD8+ T cell responses following replication-defective adenovirus serotype 5 immunization are dependent on CD11c+ dendritic cells but show redundancy in their requirement of TLR and nucleotide-binding oligomerization domain-like receptor signaling. Journal of Immunology (Baltimore, Md. : 1950). 185: 1513-21. PMID 20610651 DOI: 10.4049/jimmunol.1000338  1
2010 Ichinohe T, Pang IK, Iwasaki A. Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nature Immunology. 11: 404-10. PMID 20383149 DOI: 10.1038/ni.1861  1
2010 Lee HK, Mattei LM, Steinberg BE, Alberts P, Lee YH, Chervonsky A, Mizushima N, Grinstein S, Iwasaki A. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 32: 227-39. PMID 20171125 DOI: 10.1016/j.immuni.2009.12.006  1
2010 Iwasaki A, Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science (New York, N.Y.). 327: 291-5. PMID 20075244 DOI: 10.1126/science.1183021  1
2009 Ichinohe T, Iwasaki A. [Inflammasomes in viral infection]. Uirusu. 59: 13-21. PMID 19927984  0.52
2009 Tal MC, Iwasaki A. Autophagy and innate recognition systems. Current Topics in Microbiology and Immunology. 335: 107-21. PMID 19802562 DOI: 10.1007/978-3-642-00302-8_5  1
2009 Wang Z, Kumamoto Y, Wang P, Gan X, Lehmann D, Smrcka AV, Cohn L, Iwasaki A, Li L, Wu D. Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5. The Journal of Biological Chemistry. 284: 28599-606. PMID 19713215 DOI: 10.1074/jbc.M109.047282  0.32
2009 Tal MC, Iwasaki A. Autophagic control of RLR signaling. Autophagy. 5: 749-50. PMID 19571662 DOI: 10.4161/auto.5.5.8789  1
2009 la Sala A, He J, Laricchia-Robbio L, Gorini S, Iwasaki A, Braun M, Yap GS, Sher A, Ozato K, Kelsall B. Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function. The Journal of Experimental Medicine. 206: 1227-35. PMID 19487420 DOI: 10.1084/jem.20080912  1
2009 Tal MC, Sasai M, Lee HK, Yordy B, Shadel GS, Iwasaki A. Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proceedings of the National Academy of Sciences of the United States of America. 106: 2770-5. PMID 19196953 DOI: 10.1073/pnas.0807694106  1
2009 Iijima N, Iwasaki A. [Mucosal immune defense against sexually transmitted diseases]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 67: 2-4. PMID 19177745  1
2009 Lee HK, Zamora M, Linehan MM, Iijima N, Gonzalez D, Haberman A, Iwasaki A. Differential roles of migratory and resident DCs in T cell priming after mucosal or skin HSV-1 infection. The Journal of Experimental Medicine. 206: 359-70. PMID 19153243 DOI: 10.1084/jem.20080601  1
2009 Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A. Inflammasome recognition of influenza virus is essential for adaptive immune responses. The Journal of Experimental Medicine. 206: 79-87. PMID 19139171 DOI: 10.1084/jem.20081667  0.52
2008 Kumamoto Y, Iwasaki A. [MHC class II-presentation of antigen by autophagy]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 53: 2286-91. PMID 21038623  0.32
2008 Iijima N, Linehan MM, Zamora M, Butkus D, Dunn R, Kehry MR, Laufer TM, Iwasaki A. Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus. The Journal of Experimental Medicine. 205: 3041-52. PMID 19047439 DOI: 10.1084/jem.20082039  1
2008 Ichinohe T, Iwasaki A, Hasegawa H. Innate sensors of influenza virus: clues to developing better intranasal vaccines. Expert Review of Vaccines. 7: 1435-45. PMID 18980544 DOI: 10.1586/14760584.7.9.1435  0.52
2008 Yap GS, Iwasaki A. Securing mucosal borders--migrant monocytes to the rescue. Cell Host & Microbe. 4: 192-4. PMID 18779043 DOI: 10.1016/j.chom.2008.08.005  1
2008 Thompson JM, Nicholson MG, Whitmore AC, Zamora M, West A, Iwasaki A, Staats HF, Johnston RE. Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node. Journal of Immunology (Baltimore, Md. : 1950). 181: 574-85. PMID 18566424  1
2008 Lee HK, Iwasaki A. Autophagy and antiviral immunity. Current Opinion in Immunology. 20: 23-9. PMID 18262399 DOI: 10.1016/j.coi.2008.01.001  0.44
2008 Miller BC, Zhao Z, Stephenson LM, Cadwell K, Pua HH, Lee HK, Mizushima NN, Iwasaki A, He YW, Swat W, Virgin HW. The autophagy gene ATG5 plays an essential role in B lymphocyte development. Autophagy. 4: 309-14. PMID 18188005  1
2008 Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, ... ... Iwasaki A, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 4: 151-75. PMID 18188003  1
2007 Iijima N, Linehan MM, Saeland S, Iwasaki A. Vaginal epithelial dendritic cells renew from bone marrow precursors. Proceedings of the National Academy of Sciences of the United States of America. 104: 19061-6. PMID 18006657 DOI: 10.1073/pnas.0707179104  1
2007 Lee HK, Iwasaki A. Innate control of adaptive immunity: dendritic cells and beyond. Seminars in Immunology. 19: 48-55. PMID 17276695 DOI: 10.1016/j.smim.2006.12.001  0.44
2007 Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science (New York, N.Y.). 315: 1398-401. PMID 17272685 DOI: 10.1126/science.1136880  1
2006 Lund JM, Linehan MM, Iijima N, Iwasaki A. Cutting Edge: Plasmacytoid dendritic cells provide innate immune protection against mucosal viral infection in situ. Journal of Immunology (Baltimore, Md. : 1950). 177: 7510-4. PMID 17114418  1
2005 Soderberg KA, Payne GW, Sato A, Medzhitov R, Segal SS, Iwasaki A. Innate control of adaptive immunity via remodeling of lymph node feed arteriole. Proceedings of the National Academy of Sciences of the United States of America. 102: 16315-20. PMID 16260739 DOI: 10.1073/pnas.0506190102  1
2004 Fleeton M, Contractor N, Leon F, He J, Wetzel D, Dermody T, Iwasaki A, Kelsall B. Involvement of dendritic cell subsets in the induction of oral tolerance and immunity. Annals of the New York Academy of Sciences. 1029: 60-5. PMID 15681744 DOI: 10.1196/annals.1309.008  1
2004 Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nature Immunology. 5: 987-95. PMID 15454922 DOI: 10.1038/ni1112  1
2004 Soderberg KA, Linehan MM, Ruddle NH, Iwasaki A. MAdCAM-1 expressing sacral lymph node in the lymphotoxin beta-deficient mouse provides a site for immune generation following vaginal herpes simplex virus-2 infection. Journal of Immunology (Baltimore, Md. : 1950). 173: 1908-13. PMID 15265924  1
2004 Lund JM, Alexopoulou L, Sato A, Karow M, Adams NC, Gale NW, Iwasaki A, Flavell RA. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proceedings of the National Academy of Sciences of the United States of America. 101: 5598-603. PMID 15034168 DOI: 10.1073/pnas.0400937101  1
2004 Linehan MM, Richman S, Krummenacher C, Eisenberg RJ, Cohen GH, Iwasaki A. In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosa. Journal of Virology. 78: 2530-6. PMID 14963155 DOI: 10.1128/JVI.78.5.2530-2536.2004  1
2003 Zhao X, Sato A, Dela Cruz CS, Linehan M, Luegering A, Kucharzik T, Shirakawa AK, Marquez G, Farber JM, Williams I, Iwasaki A. CCL9 is secreted by the follicle-associated epithelium and recruits dome region Peyer's patch CD11b+ dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 2797-803. PMID 12960300  1
2003 Lund J, Sato A, Akira S, Medzhitov R, Iwasaki A. Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. The Journal of Experimental Medicine. 198: 513-20. PMID 12900525 DOI: 10.1084/jem.20030162  1
2003 Zhao X, Deak E, Soderberg K, Linehan M, Spezzano D, Zhu J, Knipe DM, Iwasaki A. Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2. The Journal of Experimental Medicine. 197: 153-62. PMID 12538655 DOI: 10.1084/jem.20021109  1
2002 Iwasaki A, Welker R, Mueller S, Linehan M, Nomoto A, Wimmer E. Immunofluorescence analysis of poliovirus receptor expression in Peyer's patches of humans, primates, and CD155 transgenic mice: implications for poliovirus infection. The Journal of Infectious Diseases. 186: 585-92. PMID 12195344 DOI: 10.1086/342682  1
2002 Park MK, Amichay D, Love P, Wick E, Liao F, Grinberg A, Rabin RL, Zhang HH, Gebeyehu S, Wright TM, Iwasaki A, Weng Y, DeMartino JA, Elkins KL, Farber JM. The CXC chemokine murine monokine induced by IFN-gamma (CXC chemokine ligand 9) is made by APCs, targets lymphocytes including activated B cells, and supports antibody responses to a bacterial pathogen in vivo. Journal of Immunology (Baltimore, Md. : 1950). 169: 1433-43. PMID 12133969  1
2002 Jameson B, Baribaud F, Pöhlmann S, Ghavimi D, Mortari F, Doms RW, Iwasaki A. Expression of DC-SIGN by dendritic cells of intestinal and genital mucosae in humans and rhesus macaques. Journal of Virology. 76: 1866-75. PMID 11799181 DOI: 10.1128/JVI.76.4.1866-1875.2002  1
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