Akiko Iwasaki - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Immunology, Microbiology Biology, Virology Biology
Website:
https://medicine.yale.edu/profile/akiko_iwasaki/

195 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Tabachnikova A, Iwasaki A. SARS-CoV-2 reprograms murine alveolar macrophages to dampen flu. Trends in Immunology. 45: 925-927. PMID 39580310 DOI: 10.1016/j.it.2024.11.002  0.37
2024 Peña-Hernández MA, Alfajaro MM, Filler RB, Moriyama M, Keeler EL, Ranglin ZE, Kong Y, Mao T, Menasche BL, Mankowski MC, Zhao Z, Vogels CBF, Hahn AM, Kalinich CC, Zhang S, ... ... Iwasaki A, et al. SARS-CoV-2-related bat viruses evade human intrinsic immunity but lack efficient transmission capacity. Nature Microbiology. PMID 39075235 DOI: 10.1038/s41564-024-01765-z  0.324
2024 Medzhitov R, Iwasaki A. Exploring new perspectives in immunology. Cell. 187: 2079-2094. PMID 38670066 DOI: 10.1016/j.cell.2024.03.038  0.307
2023 Moriyama M, Lucas C, Monteiro VS, Iwasaki A. Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221652120. PMID 37036977 DOI: 10.1073/pnas.2221652120  0.308
2023 Weizman OE, Luyten S, Krykbaeva I, Song E, Mao T, Bosenberg M, Iwasaki A. Type 2 Dendritic Cells Orchestrate a Local Immune Circuit to Confer Antimetastatic Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 36881866 DOI: 10.4049/jimmunol.2200697  0.33
2022 Asashima H, Mohanty S, Comi M, Ruff WE, Hoehn KB, Wong P, Klein J, Lucas C, Cohen I, Coffey S, Lele N, Greta L, Raddassi K, Chaudhary O, Unterman A, ... ... Iwasaki A, et al. PD-1CXCR5CD4 peripheral helper T cells promote CXCR3 plasmablasts in human acute viral infection. Cell Reports. 111895. PMID 36596303 DOI: 10.1016/j.celrep.2022.111895  0.337
2022 Moriyama M, Lucas C, Monteiro VS, Iwasaki A. SARS-CoV-2 variants do not evolve to promote further escape from MHC-I recognition. Biorxiv : the Preprint Server For Biology. PMID 35547852 DOI: 10.1101/2022.05.04.490614  0.324
2022 Sefik E, Qu R, Junqueira C, Kaffe E, Mirza H, Zhao J, Brewer JR, Han A, Steach HR, Israelow B, Blackburn HN, Velazquez S, Chen YG, Halene S, Iwasaki A, et al. Inflammasome activation in infected macrophages drives COVID-19 pathology. Nature. PMID 35483404 DOI: 10.1038/s41586-022-04802-1  0.316
2022 Unterman A, Sumida TS, Nouri N, Yan X, Zhao AY, Gasque V, Schupp JC, Asashima H, Liu Y, Cosme C, Deng W, Chen M, Raredon MSB, Hoehn KB, Wang G, ... ... Iwasaki A, et al. Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19. Nature Communications. 13: 440. PMID 35064122 DOI: 10.1038/s41467-021-27716-4  0.364
2022 Mao T, Israelow B, Lucas C, Vogels CBF, Gomez-Calvo ML, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M, Wilen CB, Landry ML, Grubaugh ND, Pyle AM, ... Iwasaki A, et al. A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice. The Journal of Experimental Medicine. 219. PMID 34757384 DOI: 10.1084/jem.20211818  0.308
2021 Israelow B, Mao T, Klein J, Song E, Menasche B, Omer SB, Iwasaki A. Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2. Science Immunology. 6: eabl4509. PMID 34623900 DOI: 10.1126/sciimmunol.abl4509  0.313
2021 Sefik E, Qu R, Kaffe E, Zhao J, Junqueira C, Mirza H, Brewer R, Han A, Steach H, Israelow B, Chen YG, Halene S, Iwasaki A, Meffre E, Nussenzweig M, et al. Viral replication in human macrophages enhances an inflammatory cascade and interferon driven chronic COVID-19 in humanized mice. Biorxiv : the Preprint Server For Biology. PMID 34611663 DOI: 10.1101/2021.09.27.461948  0.309
2021 Mao T, Israelow B, Lucas C, Vogels CBF, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M, Wilen CB, Landry ML, Grubaugh ND, Pyle AM, Iwasaki A. A stem-loop RNA RIG-I agonist confers prophylactic and therapeutic protection against acute and chronic SARS-CoV-2 infection in mice. Biorxiv : the Preprint Server For Biology. PMID 34159330 DOI: 10.1101/2021.06.16.448754  0.335
2021 Israelow B, Mao T, Klein J, Song E, Menasche B, Omer SB, Iwasaki A. Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 34031656 DOI: 10.1101/2021.05.19.444825  0.338
2021 Klein J, Brito A, Trubin P, Lu P, Wong P, Alpert T, Pena-Hernandez M, Haynes W, Kamath K, Liu F, Vogels C, Fauver J, Lucas C, Oh JE, Mao T, ... ... Iwasaki A, et al. Longitudinal immune profiling of a SARS-CoV-2 reinfection in a solid organ transplant recipient. Research Square. PMID 34013255 DOI: 10.21203/rs.3.rs-405958/v1  0.304
2021 Wang EY, Mao T, Klein J, Dai Y, Huck JD, Jaycox JR, Liu F, Zhou T, Israelow B, Wong P, Coppi A, Lucas C, Silva J, Oh JE, Song E, ... ... Iwasaki A, et al. Diverse Functional Autoantibodies in Patients with COVID-19. Nature. PMID 34010947 DOI: 10.1038/s41586-021-03631-y  0.336
2021 Klein J, Brito AF, Trubin P, Lu P, Wong P, Alpert T, Peña-Hernández MA, Haynes W, Kamath K, Liu F, Vogels CBF, Fauver JR, Lucas C, Oh J, Mao T, ... ... Iwasaki A, et al. Case Study: Longitudinal immune profiling of a SARS-CoV-2 reinfection in a solid organ transplant recipient. Medrxiv : the Preprint Server For Health Sciences. PMID 33791729 DOI: 10.1101/2021.03.24.21253992  0.323
2021 Sefik E, Israelow B, Zhao J, Qu R, Song E, Mirza H, Kaffe E, Halene S, Meffre E, Kluger Y, Nussenzweig M, Wilen C, Iwasaki A, Flavell RA. A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options. Research Square. PMID 33758831 DOI: 10.21203/rs.3.rs-279341/v1  0.329
2021 Ravindra NG, Alfajaro MM, Gasque V, Huston NC, Wan H, Szigeti-Buck K, Yasumoto Y, Greaney AM, Habet V, Chow RD, Chen JS, Wei J, Filler RB, Wang B, Wang G, ... ... Iwasaki A, et al. Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes. Plos Biology. 19: e3001143. PMID 33730024 DOI: 10.1371/journal.pbio.3001143  0.332
2020 Wang EY, Mao T, Klein J, Dai Y, Huck JD, Liu F, Zheng NS, Zhou T, Israelow B, Wong P, Lucas C, Silva J, Oh JE, Song E, Perotti ES, ... ... Iwasaki A, et al. Diverse Functional Autoantibodies in Patients with COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 33330894 DOI: 10.1101/2020.12.10.20247205  0.325
2020 Stefan KL, Kim MV, Iwasaki A, Kasper DL. Commensal Microbiota Modulation of Natural Resistance to Virus Infection. Cell. PMID 33212011 DOI: 10.1016/j.cell.2020.10.047  0.343
2020 Kim DJ, Khoury-Hanold W, Jain PC, Klein J, Kong Y, Pope SD, Ge W, Medzhitov R, Iwasaki A. RUNX binding sites are enriched in herpesvirus genomes and RUNX1 overexpression leads to HSV-1 suppression. Journal of Virology. PMID 32878886 DOI: 10.1128/Jvi.00943-20  0.37
2020 Takahashi T, Ellingson MK, Wong P, Israelow B, Lucas C, Klein J, Silva J, Mao T, Oh JE, Tokuyama M, Lu P, Venkataraman A, Park A, Liu F, Meir A, ... ... Iwasaki A, et al. Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature. PMID 32846427 DOI: 10.1038/S41586-020-2700-3  0.344
2020 Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A. Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling. The Journal of Experimental Medicine. 217. PMID 32750141 DOI: 10.1084/Jem.20201241  0.407
2020 Lu-Culligan A, Iwasaki A. The Role of Immune Factors in Shaping Fetal Neurodevelopment. Annual Review of Cell and Developmental Biology. PMID 32722920 DOI: 10.1146/Annurev-Cellbio-021120-033518  0.376
2020 Lucas C, Wong P, Klein J, Castro TBR, Silva J, Sundaram M, Ellingson MK, Mao T, Oh JE, Israelow B, Takahashi T, Tokuyama M, Lu P, Venkataraman A, Park A, ... ... Iwasaki A, et al. Longitudinal analyses reveal immunological misfiring in severe COVID-19. Nature. PMID 32717743 DOI: 10.1038/S41586-020-2588-Y  0.37
2020 Ravindra NG, Alfajaro MM, Gasque V, Wei J, Filler RB, Huston NC, Wan H, Szigeti-Buck K, Wang B, Montgomery RR, Eisenbarth SC, Williams A, Pyle AM, Iwasaki A, Horvath TL, et al. Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells. Biorxiv : the Preprint Server For Biology. PMID 32511382 DOI: 10.1101/2020.05.06.081695  0.333
2020 Gao Y, Vasic R, Song Y, Teng R, Liu C, Gbyli R, Biancon G, Nelakanti R, Lobben K, Kudo E, Liu W, Ardasheva A, Fu X, Wang X, Joshi P, ... ... Iwasaki A, et al. mA Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development. Immunity. PMID 32497523 DOI: 10.1016/J.Immuni.2020.05.003  0.415
2020 Yap JKY, Moriyama M, Iwasaki A. Inflammasomes and Pyroptosis as Therapeutic Targets for COVID-19. Journal of Immunology (Baltimore, Md. : 1950). PMID 32493814 DOI: 10.4049/Jimmunol.2000513  0.348
2020 Park A, Iwasaki A. Type I and Type III Interferons - Induction, Signaling, Evasion, and Application to Combat COVID-19. Cell Host & Microbe. PMID 32464097 DOI: 10.1016/J.Chom.2020.05.008  0.385
2020 Yockey LJ, Lucas C, Iwasaki A. Contributions of maternal and fetal antiviral immunity in congenital disease. Science (New York, N.Y.). 368: 608-612. PMID 32381717 DOI: 10.1126/Science.Aaz1960  0.389
2020 Iwasaki A, Grubaugh ND. Why does Japan have so few cases of COVID-19? Embo Molecular Medicine. e12481. PMID 32275804 DOI: 10.15252/Emmm.202012481  0.321
2020 Moriyama M, Hugentobler WJ, Iwasaki A. Seasonality of Respiratory Viral Infections. Annual Review of Virology. PMID 32196426 DOI: 10.1146/Annurev-Virology-012420-022445  0.401
2020 Gopinath S, Lu P, Iwasaki A. Cutting Edge: The Use of Topical Aminoglycosides as an Effective Pull in "Prime and Pull" Vaccine Strategy. Journal of Immunology (Baltimore, Md. : 1950). PMID 32122994 DOI: 10.4049/Jimmunol.1900462  0.45
2020 Song E, Mao T, Dong H, Boisserand LSB, Antila S, Bosenberg M, Alitalo K, Thomas JL, Iwasaki A. VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours. Nature. PMID 31942068 DOI: 10.1038/S41586-019-1912-X  0.375
2019 Ren X, Linehan MM, Iwasaki A, Pyle AM. RIG-I Recognition of RNA Targets: The Influence of Terminal Base Pair Sequence and Overhangs on Affinity and Signaling. Cell Reports. 29: 3807-3815.e3. PMID 31851914 DOI: 10.1016/J.Celrep.2019.11.052  0.329
2019 Goldberg EL, Molony RD, Kudo E, Sidorov S, Kong Y, Dixit VD, Iwasaki A. Ketogenic diet activates protective γδ T cell responses against influenza virus infection. Science Immunology. 4. PMID 31732517 DOI: 10.1126/Sciimmunol.Aav2026  0.416
2019 Jiang X, Muthusamy V, Fedorova O, Kong Y, Kim DJ, Bosenberg M, Pyle AM, Iwasaki A. Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses. The Journal of Experimental Medicine. PMID 31601678 DOI: 10.1084/Jem.20190801  0.357
2019 Amezcua Vesely MC, Pallis P, Bielecki P, Low JS, Zhao J, Harman CCD, Kroehling L, Jackson R, Bailis W, Licona-Limón P, Xu H, Iijima N, Pillai PS, Kaplan DH, Weaver CT, ... ... Iwasaki A, et al. Effector T17 Cells Give Rise to Long-Lived T Cells that Are Essential for an Immediate Response against Bacterial Infection. Cell. 178: 1176-1188.e15. PMID 31442406 DOI: 10.1016/J.Cell.2019.07.032  0.396
2019 Pi R, Iwasaki A, Sewald X, Mothes W, Uchil PD. Murine Leukemia Virus exploits innate sensing by TLR7 in B-1 cells to establish infection and local spread in mice. Journal of Virology. PMID 31434732 DOI: 10.1128/Jvi.00930-19  0.491
2019 Treger RS, Tokuyama M, Dong H, Salas-Briceno K, Ross SR, Kong Y, Iwasaki A. Human APOBEC3G prevents emergence of infectious endogenous retrovirus in mice. Journal of Virology. PMID 31341050 DOI: 10.1128/Jvi.00728-19  0.34
2019 Oh JE, Iijima N, Song E, Lu P, Klein J, Jiang R, Kleinstein SH, Iwasaki A. Migrant memory B cells secrete luminal antibody in the vagina. Nature. PMID 31189952 DOI: 10.1038/S41586-019-1285-1  0.394
2019 Kudo E, Song E, Yockey LJ, Rakib T, Wong PW, Homer RJ, Iwasaki A. Low ambient humidity impairs barrier function and innate resistance against influenza infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 31085641 DOI: 10.1073/Pnas.1902840116  0.447
2019 Uraki R, Hastings AK, Marin-Lopez A, Sumida T, Takahashi T, Grover JR, Iwasaki A, Hafler DA, Montgomery RR, Fikrig E. Aedes aegypti AgBR1 antibodies modulate early Zika virus infection of mice. Nature Microbiology. PMID 30858571 DOI: 10.1038/S41564-019-0385-X  0.421
2019 Gao Y, Vasic R, Song Y, Teng R, Gbyli R, Biancon G, Nelakanti R, Kudo E, Liu W, Ardasheva A, Fu X, Wang X, Joshi P, Dura B, Lee V, ... ... Iwasaki A, et al. Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Innate Immune Response and Hematopoietic Failure Blood. 134: 450-450. DOI: 10.1182/Blood-2019-130442  0.378
2019 Yockey L, Jurado K, Condiff E, Iwasaki A. Hematopoietic type I interferon signaling controls Zika virus viremia after intravaginal exposure American Journal of Obstetrics and Gynecology. 221: 675. DOI: 10.1016/J.Ajog.2019.10.094  0.341
2018 Yockey LJ, Iwasaki A. Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development. Immunity. 49: 397-412. PMID 30231982 DOI: 10.1016/J.Immuni.2018.07.017  0.328
2018 Mihaylova VT, Kong Y, Fedorova O, Sharma L, Dela Cruz CS, Pyle AM, Iwasaki A, Foxman EF. Regional Differences in Airway Epithelial Cells Reveal Tradeoff between Defense against Oxidative Stress and Defense against Rhinovirus. Cell Reports. 24: 3000-3007.e3. PMID 30208323 DOI: 10.1016/J.Celrep.2018.08.033  0.421
2018 Orzalli MH, Smith A, Jurado KA, Iwasaki A, Garlick JA, Kagan JC. An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication. Molecular Cell. PMID 30100266 DOI: 10.1016/J.Molcel.2018.07.009  0.453
2018 Lucas CGO, Kitoko JZ, Ferreira FM, Suzart VG, Papa MP, Coelho SVA, Cavazzoni CB, Paula-Neto HA, Olsen PC, Iwasaki A, Pereira RM, Pimentel-Coelho PM, Vale AM, de Arruda LB, Bozza MT. Critical role of CD4 T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection. Nature Communications. 9: 3136. PMID 30087337 DOI: 10.1038/S41467-018-05519-4  0.424
2018 Wu L, Cao J, Cai WL, Lang SM, Horton JR, Jansen DJ, Liu ZZ, Chen JF, Zhang M, Mott BT, Pohida K, Rai G, Kales SC, Henderson MJ, Hu X, ... ... Iwasaki A, et al. KDM5 histone demethylases repress immune response via suppression of STING. Plos Biology. 16: e2006134. PMID 30080846 DOI: 10.1371/Journal.Pbio.2006134  0.422
2018 Hayashi K, Taura M, Iwasaki A. The interaction between IKKα and LC3 promotes type I interferon production through the TLR9-containing LAPosome. Science Signaling. 11. PMID 29717061 DOI: 10.1126/Scisignal.Aan4144  0.393
2018 Gopinath S, Kim MV, Rakib T, Wong PW, van Zandt M, Barry NA, Kaisho T, Goodman AL, Iwasaki A. Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner. Nature Microbiology. PMID 29632368 DOI: 10.1038/S41564-018-0138-2  0.463
2018 Linehan MM, Dickey TH, Molinari ES, Fitzgerald ME, Potapova O, Iwasaki A, Pyle AM. A minimal RNA ligand for potent RIG-I activation in living mice. Science Advances. 4: e1701854. PMID 29492454 DOI: 10.1126/Sciadv.1701854  0.369
2018 Yockey LJ, Jurado KA, Arora N, Millet A, Rakib T, Milano KM, Hastings AK, Fikrig E, Kong Y, Horvath TL, Weatherbee S, Kliman HJ, Coyne CB, Iwasaki A. Type I interferons instigate fetal demise after Zika virus infection. Science Immunology. 3. PMID 29305462 DOI: 10.1126/Sciimmunol.Aao1680  0.415
2018 Han P, Hanlon D, Filler R, Robinson E, Zhang K, Fan R, Iwasaki A, Fahmy T, Edelson R. 111 Role of platelets in the differentiation of monocytes into dendritic cell-like antigen presenting cells Journal of Investigative Dermatology. 138: S19. DOI: 10.1016/J.Jid.2018.03.115  0.358
2017 Molony RD, Nguyen JT, Kong Y, Montgomery RR, Shaw AC, Iwasaki A. Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes. Science Signaling. 10. PMID 29233916 DOI: 10.1126/Scisignal.Aan2392  0.4
2017 Jurado KA, Yockey LJ, Wong PW, Lee S, Huttner AJ, Iwasaki A. Antiviral CD8 T cells induce Zika-virus-associated paralysis in mice. Nature Microbiology. PMID 29158604 DOI: 10.1038/S41564-017-0060-Z  0.436
2017 Jurado KA, Iwasaki A. Zika virus targets blood monocytes. Nature Microbiology. 2: 1460-1461. PMID 29070824 DOI: 10.1038/S41564-017-0049-7  0.391
2017 Gibb DR, Liu J, Santhanakrishnan M, Natarajan P, Madrid DJ, Patel S, Eisenbarth SC, Tormey CA, Stowell SR, Iwasaki A, Hendrickson JE. B cells require Type 1 interferon to produce alloantibodies to transfused KEL-expressing red blood cells in mice. Transfusion. PMID 28836263 DOI: 10.1111/Trf.14288  0.371
2017 Wong P, Iwasaki A. RAB15 empowers dendritic cells to drive antiviral immunity. Science Immunology. 2. PMID 28783705 DOI: 10.1126/Sciimmunol.Aan6448  0.45
2017 Gibb DR, Liu J, Natarajan P, Santhanakrishnan M, Madrid DJ, Eisenbarth SC, Zimring JC, Iwasaki A, Hendrickson JE. Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 28630094 DOI: 10.4049/Jimmunol.1700401  0.356
2017 Chen YG, Kim MV, Chen X, Batista PJ, Aoyama S, Wilusz JE, Iwasaki A, Chang HY. Sensing Self and Foreign Circular RNAs by Intron Identity. Molecular Cell. PMID 28625551 DOI: 10.1016/J.Molcel.2017.05.022  0.361
2017 Sasai M, Sakaguchi N, Ma JS, Nakamura S, Kawabata T, Bando H, Lee Y, Saitoh T, Akira S, Iwasaki A, Standley DM, Yoshimori T, Yamamoto M. Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense. Nature Immunology. PMID 28604719 DOI: 10.1038/Ni.3767  0.406
2017 Fink SL, Jayewickreme TR, Molony RD, Iwawaki T, Landis CS, Lindenbach BD, Iwasaki A. IRE1α promotes viral infection by conferring resistance to apoptosis. Science Signaling. 10. PMID 28588082 DOI: 10.1126/Scisignal.Aai7814  0.426
2017 Hastings AK, Yockey LJ, Jagger BW, Hwang J, Uraki R, Gaitsch HF, Parnell LA, Cao B, Mysorekar IU, Rothlin CV, Fikrig E, Diamond MS, Iwasaki A. TAM Receptors Are Not Required for Zika Virus Infection in Mice. Cell Reports. 19: 558-568. PMID 28423319 DOI: 10.1016/J.Celrep.2017.03.058  0.395
2017 Uraki R, Hwang J, Jurado KA, Householder S, Yockey LJ, Hastings AK, Homer RJ, Iwasaki A, Fikrig E. Zika virus causes testicular atrophy. Science Advances. 3: e1602899. PMID 28261663 DOI: 10.1126/Sciadv.1602899  0.41
2017 Goldberg EL, Asher JL, Molony RD, Shaw AC, Zeiss CJ, Wang C, Morozova-Roche LA, Herzog RI, Iwasaki A, Dixit VD. β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares. Cell Reports. 18: 2077-2087. PMID 28249154 DOI: 10.1016/J.Celrep.2017.02.004  0.309
2017 Iwasaki A. Immune Regulation of Antibody Access to Neuronal Tissues. Trends in Molecular Medicine. PMID 28185790 DOI: 10.1016/J.Molmed.2017.01.004  0.421
2016 Iwasaki A, Foxman EF, Molony RD. Early local immune defences in the respiratory tract. Nature Reviews. Immunology. PMID 27890913 DOI: 10.1038/Nri.2016.117  0.444
2016 Shin H, Kumamoto Y, Gopinath S, Iwasaki A. CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2. Nature Communications. 7: 13346. PMID 27827367 DOI: 10.1038/Ncomms13346  0.423
2016 Kumamoto Y, Hirai T, Wong PW, Kaplan DH, Iwasaki A. CD301b(+) dendritic cells suppress T follicular helper cells and antibody responses to protein antigens. Elife. 5. PMID 27657168 DOI: 10.7554/Elife.17979  0.357
2016 Yockey LJ, Varela L, Rakib T, Khoury-Hanold W, Fink SL, Stutz B, Szigeti-Buck K, Van den Pol A, Lindenbach BD, Horvath TL, Iwasaki A. Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection. Cell. 166: 1247-1256.e4. PMID 27565347 DOI: 10.1016/J.Cell.2016.08.004  0.391
2016 Foxman EF, Storer JA, Vanaja K, Levchenko A, Iwasaki A. Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature. Proceedings of the National Academy of Sciences of the United States of America. PMID 27402752 DOI: 10.1073/Pnas.1601942113  0.419
2016 Schmid ET, Pang IK, Carrera Silva EA, Bosurgi L, Miner JJ, Diamond MS, Iwasaki A, Rothlin CV. AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity. Elife. 5. PMID 27350258 DOI: 10.7554/Elife.12414  0.831
2016 Khoury-Hanold W, Yordy B, Kong P, Kong Y, Ge W, Szigeti-Buck K, Ralevski A, Horvath TL, Iwasaki A. Viral Spread to Enteric Neurons Links Genital HSV-1 Infection to Toxic Megacolon and Lethality. Cell Host & Microbe. 19: 788-99. PMID 27281569 DOI: 10.1016/J.Chom.2016.05.008  0.798
2016 Iijima N, Iwasaki A. Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help. Nature. 533: 552-6. PMID 27225131 DOI: 10.1038/Nature17979  0.398
2016 Iwasaki A. Exploiting Mucosal Immunity for Antiviral Vaccines. Annual Review of Immunology. 34: 575-608. PMID 27168245 DOI: 10.1146/Annurev-Immunol-032414-112315  0.396
2016 Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, ... ... Iwasaki A, et al. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science (New York, N.Y.). 352: 463-6. PMID 27102485 DOI: 10.1126/Science.Aaf3926  0.795
2016 Gopinath S, Kumamoto Y, Iwasaki A. O-linked sugars sound the alarm. Nature Immunology. 17: 119-20. PMID 26784258 DOI: 10.1038/Ni.3364  0.479
2016 Khoury-Hanold W, Iwasaki A. Autophagy Snuffs a Macrophage's Inner Fire. Cell Host & Microbe. 19: 9-11. PMID 26764592 DOI: 10.1016/J.Chom.2015.12.015  0.374
2016 Kumamoto Y, Hirai T, Wong PW, Kaplan DH, Iwasaki A. Author response: CD301b+ dendritic cells suppress T follicular helper cells and antibody responses to protein antigens Elife. DOI: 10.7554/Elife.17979.022  0.379
2016 Schmid ET, Pang IK, Silva EAC, Bosurgi L, Miner JJ, Diamond MS, Iwasaki A, Rothlin CV. Author response: AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity Elife. DOI: 10.7554/Elife.12414.023  0.798
2016 Gibb DR, Natarajan P, Liu J, Santhanakrishnan M, Iwasaki A, Hendrickson JE. Type 1 Interferon Regulates Inflammation Associated RBC Alloimmunization By Promoting Monocyte-Derived Dendritic Cell Erythrophagocytosis in Mice Blood. 128: 19-19. DOI: 10.1182/Blood.V128.22.19.19  0.313
2015 Iijima N, Iwasaki A. Tissue instruction for migration and retention of TRM cells. Trends in Immunology. 36: 556-64. PMID 26282885 DOI: 10.1016/J.It.2015.07.002  0.401
2015 Hayashi K, Sasai M, Iwasaki A. Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity. International Immunology. PMID 25925170 DOI: 10.1093/Intimm/Dxv021  0.422
2015 Saglam O, Samayoa E, Somasekar S, Naccache S, Iwasaki A, Chiu CY. No viral association found in a set of differentiated vulvar intraepithelial neoplasia cases by human papillomavirus and pan-viral microarray testing. Plos One. 10: e0125292. PMID 25894343 DOI: 10.1371/Journal.Pone.0125292  0.309
2015 Iwasaki A, Medzhitov R. Control of adaptive immunity by the innate immune system. Nature Immunology. 16: 343-53. PMID 25789684 DOI: 10.1038/Ni.3123  0.467
2015 Lipovsky A, Zhang W, Iwasaki A, DiMaio D. Application of the proximity-dependent assay and fluorescence imaging approaches to study viral entry pathways. Methods in Molecular Biology (Clifton, N.J.). 1270: 437-51. PMID 25702134 DOI: 10.1007/978-1-4939-2309-0_30  0.397
2015 Kashem SW, Igyártó BZ, Gerami-Nejad M, Kumamoto Y, Mohammed J, Jarrett E, Drummond RA, Zurawski SM, Zurawski G, Berman J, Iwasaki A, Brown GD, Kaplan DH. Candida albicans morphology and dendritic cell subsets determine T helper cell differentiation. Immunity. 42: 356-66. PMID 25680275 DOI: 10.1016/J.Immuni.2015.01.008  0.447
2015 West AP, Khoury-Hanold W, Staron M, Tal MC, Pineda CM, Lang SM, Bestwick M, Duguay BA, Raimundo N, MacDuff DA, Kaech SM, Smiley JR, Means RE, Iwasaki A, Shadel GS. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 520: 553-7. PMID 25642965 DOI: 10.1038/Nature14156  0.767
2015 Foxman EF, Storer JA, Fitzgerald ME, Wasik BR, Hou L, Zhao H, Turner PE, Pyle AM, Iwasaki A. Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 827-32. PMID 25561542 DOI: 10.1073/Pnas.1411030112  0.38
2015 Iwasaki A. ID: 8 Cytokine. 76: 58. DOI: 10.1016/J.Cyto.2015.08.012  0.451
2014 Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA. Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. Cell. 159: 1563-77. PMID 25525875 DOI: 10.1016/J.Cell.2014.11.037  0.806
2014 Iijima N, Iwasaki A. T cell memory. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells. Science (New York, N.Y.). 346: 93-8. PMID 25170048 DOI: 10.1126/Science.1257530  0.371
2014 Khan S, Toyoda H, Linehan M, Iwasaki A, Nomoto A, Bernhardt G, Cello J, Wimmer E. Poliomyelitis in transgenic mice expressing CD155 under the control of the Tage4 promoter after oral and parenteral poliovirus inoculation. The Journal of General Virology. 95: 1668-76. PMID 24784416 DOI: 10.1099/Vir.0.064535-0  0.335
2014 Iwasaki A, Pillai PS. Innate immunity to influenza virus infection. Nature Reviews. Immunology. 14: 315-28. PMID 24762827 DOI: 10.1038/Nri3665  0.487
2014 Guo YE, Riley KJ, Iwasaki A, Steitz JA. Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function. Molecular Cell. 54: 67-79. PMID 24725595 DOI: 10.1016/J.Molcel.2014.03.025  0.328
2014 Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC. A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction. Cell. 156: 705-16. PMID 24529375 DOI: 10.1016/J.Cell.2014.01.019  0.4
2014 Ding S, Khoury-Hanold W, Iwasaki A, Robek MD. Epigenetic reprogramming of the type III interferon response potentiates antiviral activity and suppresses tumor growth. Plos Biology. 12: e1001758. PMID 24409098 DOI: 10.1371/Journal.Pbio.1001758  0.417
2013 You F, Wang P, Yang L, Yang G, Zhao YO, Qian F, Walker W, Sutton R, Montgomery R, Lin R, Iwasaki A, Fikrig E. ELF4 is critical for induction of type I interferon and the host antiviral response. Nature Immunology. 14: 1237-46. PMID 24185615 DOI: 10.1038/Ni.2756  0.459
2013 Kumamoto Y, Linehan M, Weinstein JS, Laidlaw BJ, Craft JE, Iwasaki A. CD301b⁺ dermal dendritic cells drive T helper 2 cell-mediated immunity. Immunity. 39: 733-43. PMID 24076051 DOI: 10.1016/J.Immuni.2013.08.029  0.463
2013 Shin H, Iwasaki A. Generating protective immunity against genital herpes. Trends in Immunology. 34: 487-94. PMID 24012144 DOI: 10.1016/J.It.2013.08.001  0.378
2013 Shin H, Iwasaki A. Tissue-resident memory T cells. Immunological Reviews. 255: 165-81. PMID 23947354 DOI: 10.1111/Imr.12087  0.359
2013 Pang IK, Pillai PS, Iwasaki A. Efficient influenza A virus replication in the respiratory tract requires signals from TLR7 and RIG-I. Proceedings of the National Academy of Sciences of the United States of America. 110: 13910-5. PMID 23918369 DOI: 10.1073/Pnas.1303275110  0.835
2013 Mattei LM, Cotmore SF, Tattersall P, Iwasaki A. Parvovirus evades interferon-dependent viral control in primary mouse embryonic fibroblasts. Virology. 442: 20-7. PMID 23676303 DOI: 10.1016/J.Virol.2013.03.020  0.762
2013 Sellers SL, Iwasaki A, Payne GW. Nitric oxide and TNFα are critical regulators of reversible lymph node vascular remodeling and adaptive immune response. Plos One. 8: e60741. PMID 23573281 DOI: 10.1371/Journal.Pone.0060741  0.4
2013 Hayashi K, Iwasaki A. Different routes to the same destination. Elife. 2: e00572. PMID 23426937 DOI: 10.7554/Elife.00572  0.364
2013 Pang IK, Ichinohe T, Iwasaki A. IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8⁺ T cell responses to influenza A virus. Nature Immunology. 14: 246-53. PMID 23314004 DOI: 10.1038/Ni.2514  0.831
2013 Mattei LM, Cotmore SF, Li L, Tattersall P, Iwasaki A. Toll-like receptor 9 in plasmacytoid dendritic cells fails to detect parvoviruses. Journal of Virology. 87: 3605-8. PMID 23302877 DOI: 10.1128/Jvi.03155-12  0.713
2013 Yordy B, Iwasaki A. Cell type-dependent requirement of autophagy in HSV-1 antiviral defense. Autophagy. 9: 236-8. PMID 23095715 DOI: 10.4161/Auto.22506  0.821
2013 Yordy B, Tal MC, Hayashi K, Arojo O, Iwasaki A. Autophagy and selective deployment of Atg proteins in antiviral defense. International Immunology. 25: 1-10. PMID 23042773 DOI: 10.1093/Intimm/Dxs101  0.795
2012 Henault J, Martinez J, Riggs JM, Tian J, Mehta P, Clarke L, Sasai M, Latz E, Brinkmann MM, Iwasaki A, Coyle AJ, Kolbeck R, Green DR, Sanjuan MA. Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes. Immunity. 37: 986-97. PMID 23219390 DOI: 10.1016/J.Immuni.2012.09.014  0.417
2012 Shin H, Iwasaki A. A vaccine strategy that protects against genital herpes by establishing local memory T cells. Nature. 491: 463-7. PMID 23075848 DOI: 10.1038/Nature11522  0.395
2012 Hoshi N, Schenten D, Nish SA, Walther Z, Gagliani N, Flavell RA, Reizis B, Shen Z, Fox JG, Iwasaki A, Medzhitov R. MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice. Nature Communications. 3: 1120. PMID 23047678 DOI: 10.1038/Ncomms2113  0.384
2012 Iwasaki A. Innate immune recognition of HIV-1. Immunity. 37: 389-98. PMID 22999945 DOI: 10.1016/J.Immuni.2012.08.011  0.321
2012 Iwasaki A. A virological view of innate immune recognition. Annual Review of Microbiology. 66: 177-96. PMID 22994491 DOI: 10.1146/Annurev-Micro-092611-150203  0.473
2012 Yordy B, Iijima N, Huttner A, Leib D, Iwasaki A. A neuron-specific role for autophagy in antiviral defense against herpes simplex virus. Cell Host & Microbe. 12: 334-45. PMID 22980330 DOI: 10.1016/J.Chom.2012.07.013  0.812
2012 Kumamoto Y, Iwasaki A. Unique features of antiviral immune system of the vaginal mucosa. Current Opinion in Immunology. 24: 411-6. PMID 22673876 DOI: 10.1016/J.Coi.2012.05.006  0.398
2012 Kagan JC, Iwasaki A. Phagosome as the organelle linking innate and adaptive immunity. Traffic (Copenhagen, Denmark). 13: 1053-61. PMID 22577865 DOI: 10.1111/J.1600-0854.2012.01377.X  0.443
2012 Shin H, Iwasaki A. Skin T(RM) mediates distributed border patrol. Cell Research. 22: 1325-7. PMID 22565287 DOI: 10.1038/Cr.2012.75  0.338
2012 Mantegazza AR, Guttentag SH, El-Benna J, Sasai M, Iwasaki A, Shen H, Laufer TM, Marks MS. Adaptor protein-3 in dendritic cells facilitates phagosomal toll-like receptor signaling and antigen presentation to CD4(+) T cells. Immunity. 36: 782-94. PMID 22560444 DOI: 10.1016/J.Immuni.2012.02.018  0.419
2012 Pang IK, Iwasaki A. Control of antiviral immunity by pattern recognition and the microbiome. Immunological Reviews. 245: 209-26. PMID 22168422 DOI: 10.1111/J.1600-065X.2011.01073.X  0.818
2011 Yordy B, Iwasaki A. Autophagy in the control and pathogenesis of viral infection. Current Opinion in Virology. 1: 196-203. PMID 21927636 DOI: 10.1016/J.Coviro.2011.05.016  0.823
2011 Iwasaki A, Medzhitov R. A new shield for a cytokine storm. Cell. 146: 861-2. PMID 21925310 DOI: 10.1016/J.Cell.2011.08.027  0.399
2011 Tal MC, Iwasaki A. Mitoxosome: a mitochondrial platform for cross-talk between cellular stress and antiviral signaling. Immunological Reviews. 243: 215-34. PMID 21884179 DOI: 10.1111/J.1600-065X.2011.01038.X  0.757
2011 Sasai M, Iwasaki A. Love triangle between Unc93B1, TLR7, and TLR9 prevents fatal attraction. Immunity. 35: 3-5. PMID 21777792 DOI: 10.1016/J.Immuni.2011.07.006  0.363
2011 Kumamoto Y, Mattei LM, Sellers S, Payne GW, Iwasaki A. CD4+ T cells support cytotoxic T lymphocyte priming by controlling lymph node input. Proceedings of the National Academy of Sciences of the United States of America. 108: 8749-54. PMID 21555577 DOI: 10.1073/Pnas.1100567108  0.713
2011 Foxman EF, Iwasaki A. Genome-virome interactions: examining the role of common viral infections in complex disease. Nature Reviews. Microbiology. 9: 254-64. PMID 21407242 DOI: 10.1038/Nrmicro2541  0.341
2011 Ichinohe T, Pang IK, Kumamoto Y, Peaper DR, Ho JH, Murray TS, Iwasaki A. Microbiota regulates immune defense against respiratory tract influenza A virus infection. Proceedings of the National Academy of Sciences of the United States of America. 108: 5354-9. PMID 21402903 DOI: 10.1073/Pnas.1019378108  0.84
2011 Iijima N, Mattei LM, Iwasaki A. Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue. Proceedings of the National Academy of Sciences of the United States of America. 108: 284-9. PMID 21173243 DOI: 10.1073/Pnas.1005201108  0.762
2011 Pang IK, Iwasaki A. Inflammasomes as mediators of immunity against influenza virus. Trends in Immunology. 32: 34-41. PMID 21147034 DOI: 10.1016/J.It.2010.11.004  0.815
2010 Sasai M, Linehan MM, Iwasaki A. Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3. Science (New York, N.Y.). 329: 1530-4. PMID 20847273 DOI: 10.1126/Science.1187029  0.411
2010 Iwasaki A. Antiviral immune responses in the genital tract: clues for vaccines. Nature Reviews. Immunology. 10: 699-711. PMID 20829886 DOI: 10.1038/Nri2836  0.39
2010 Lindsay RW, Darrah PA, Quinn KM, Wille-Reece U, Mattei LM, Iwasaki A, Kasturi SP, Pulendran B, Gall JG, Spies AG, Seder RA. CD8+ T cell responses following replication-defective adenovirus serotype 5 immunization are dependent on CD11c+ dendritic cells but show redundancy in their requirement of TLR and nucleotide-binding oligomerization domain-like receptor signaling. Journal of Immunology (Baltimore, Md. : 1950). 185: 1513-21. PMID 20610651 DOI: 10.4049/Jimmunol.1000338  0.745
2010 Ichinohe T, Pang IK, Iwasaki A. Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nature Immunology. 11: 404-10. PMID 20383149 DOI: 10.1038/Ni.1861  0.793
2010 Lee HK, Mattei LM, Steinberg BE, Alberts P, Lee YH, Chervonsky A, Mizushima N, Grinstein S, Iwasaki A. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 32: 227-39. PMID 20171125 DOI: 10.1016/J.Immuni.2009.12.006  0.711
2010 Iwasaki A, Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science (New York, N.Y.). 327: 291-5. PMID 20075244 DOI: 10.1126/Science.1183021  0.465
2009 Ichinohe T, Iwasaki A. [Inflammasomes in viral infection]. Uirusu. 59: 13-21. PMID 19927984 DOI: 10.2222/Jsv.59.13  0.467
2009 Nakanishi Y, Lu B, Gerard C, Iwasaki A. CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help. Nature. 462: 510-3. PMID 19898495 DOI: 10.1038/Nature08511  0.387
2009 Tal MC, Iwasaki A. Autophagy and innate recognition systems. Current Topics in Microbiology and Immunology. 335: 107-21. PMID 19802562 DOI: 10.1007/978-3-642-00302-8_5  0.793
2009 Wang Z, Kumamoto Y, Wang P, Gan X, Lehmann D, Smrcka AV, Cohn L, Iwasaki A, Li L, Wu D. Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5. The Journal of Biological Chemistry. 284: 28599-606. PMID 19713215 DOI: 10.1074/Jbc.M109.047282  0.393
2009 Tal MC, Iwasaki A. Autophagic control of RLR signaling. Autophagy. 5: 749-50. PMID 19571662 DOI: 10.4161/Auto.5.5.8789  0.79
2009 la Sala A, He J, Laricchia-Robbio L, Gorini S, Iwasaki A, Braun M, Yap GS, Sher A, Ozato K, Kelsall B. Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function. The Journal of Experimental Medicine. 206: 1227-35. PMID 19487420 DOI: 10.1084/Jem.20080912  0.615
2009 Iwasaki A. Local advantage: skin DCs prime; skin memory T cells protect. Nature Immunology. 10: 451-3. PMID 19381136 DOI: 10.1038/Ni0509-451  0.411
2009 Tal MC, Sasai M, Lee HK, Yordy B, Shadel GS, Iwasaki A. Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proceedings of the National Academy of Sciences of the United States of America. 106: 2770-5. PMID 19196953 DOI: 10.1073/Pnas.0807694106  0.796
2009 Lee HK, Zamora M, Linehan MM, Iijima N, Gonzalez D, Haberman A, Iwasaki A. Differential roles of migratory and resident DCs in T cell priming after mucosal or skin HSV-1 infection. The Journal of Experimental Medicine. 206: 359-70. PMID 19153243 DOI: 10.1084/Jem.20080601  0.442
2009 Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A. Inflammasome recognition of influenza virus is essential for adaptive immune responses. The Journal of Experimental Medicine. 206: 79-87. PMID 19139171 DOI: 10.1084/Jem.20081667  0.545
2009 Ramanathan B, Iwasaki A. Innate recognition of viral infection and the involvement of autophagy Rna Viruses: Host Gene Responses to Infections. 209-228. DOI: 10.1142/9789812833808_0009  0.432
2009 La Sala A, He J, Laricchia-Robbio L, Gorini S, Iwasaki A, Braun M, Yap GS, Sher A, Ozato K, Kelsall B. Cholera toxin inhibits IL-12 production and CD8α+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function (Journal of Experimental Medicine (2009) 206, 6, (1227-1235)) Journal of Experimental Medicine. 206: 1635. DOI: 10.1084/Jem.2008091262209C  0.598
2008 Iijima N, Thompson JM, Iwasaki A. Dendritic cells and macrophages in the genitourinary tract. Mucosal Immunology. 1: 451-9. PMID 19079212 DOI: 10.1038/Mi.2008.57  0.453
2008 Iijima N, Linehan MM, Zamora M, Butkus D, Dunn R, Kehry MR, Laufer TM, Iwasaki A. Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus. The Journal of Experimental Medicine. 205: 3041-52. PMID 19047439 DOI: 10.1084/Jem.20082039  0.502
2008 Ichinohe T, Iwasaki A, Hasegawa H. Innate sensors of influenza virus: clues to developing better intranasal vaccines. Expert Review of Vaccines. 7: 1435-45. PMID 18980544 DOI: 10.1586/14760584.7.9.1435  0.453
2008 Yap GS, Iwasaki A. Securing mucosal borders--migrant monocytes to the rescue. Cell Host & Microbe. 4: 192-4. PMID 18779043 DOI: 10.1016/J.Chom.2008.08.005  0.379
2008 Thompson JM, Nicholson MG, Whitmore AC, Zamora M, West A, Iwasaki A, Staats HF, Johnston RE. Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node. Journal of Immunology (Baltimore, Md. : 1950). 181: 574-85. PMID 18566424 DOI: 10.4049/Jimmunol.181.1.574  0.464
2008 Thompson JM, Iwasaki A. Toll-like receptors regulation of viral infection and disease. Advanced Drug Delivery Reviews. 60: 786-94. PMID 18280610 DOI: 10.1016/J.Addr.2007.11.003  0.488
2008 Lee HK, Iwasaki A. Autophagy and antiviral immunity. Current Opinion in Immunology. 20: 23-9. PMID 18262399 DOI: 10.1016/J.Coi.2008.01.001  0.537
2007 Iijima N, Linehan MM, Saeland S, Iwasaki A. Vaginal epithelial dendritic cells renew from bone marrow precursors. Proceedings of the National Academy of Sciences of the United States of America. 104: 19061-6. PMID 18006657 DOI: 10.1073/Pnas.0707179104  0.368
2007 Iwasaki A. Role of autophagy in innate viral recognition. Autophagy. 3: 354-6. PMID 17404496 DOI: 10.4161/Auto.4114  0.503
2007 Iwasaki A. Mucosal dendritic cells. Annual Review of Immunology. 25: 381-418. PMID 17378762 DOI: 10.1146/Annurev.Immunol.25.022106.141634  0.437
2007 Iwasaki A. Division of labor by dendritic cells. Cell. 128: 435-6. PMID 17289563 DOI: 10.1016/J.Cell.2007.01.024  0.341
2007 Lee HK, Iwasaki A. Innate control of adaptive immunity: dendritic cells and beyond. Seminars in Immunology. 19: 48-55. PMID 17276695 DOI: 10.1016/J.Smim.2006.12.001  0.489
2007 Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science (New York, N.Y.). 315: 1398-401. PMID 17272685 DOI: 10.1126/Science.1136880  0.487
2006 Lund JM, Linehan MM, Iijima N, Iwasaki A. Cutting Edge: Plasmacytoid dendritic cells provide innate immune protection against mucosal viral infection in situ. Journal of Immunology (Baltimore, Md. : 1950). 177: 7510-4. PMID 17114418 DOI: 10.4049/Jimmunol.177.11.7510  0.548
2006 Sato A, Linehan MM, Iwasaki A. Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 17343-8. PMID 17085599 DOI: 10.1073/Pnas.0605102103  0.453
2006 Iwasaki A. The use of bone marrow-chimeric mice in elucidating immune mechanisms. Methods in Molecular Medicine. 127: 281-92. PMID 16988461 DOI: 10.1385/1-59745-168-1:281  0.338
2006 Shen H, Iwasaki A. A crucial role for plasmacytoid dendritic cells in antiviral protection by CpG ODN-based vaginal microbicide. The Journal of Clinical Investigation. 116: 2237-43. PMID 16878177 DOI: 10.1172/Jci28681  0.504
2006 Colonna M, Pulendran B, Iwasaki A. Dendritic cells at the host-pathogen interface. Nature Immunology. 7: 117-20. PMID 16424884 DOI: 10.1038/Ni0206-117  0.421
2005 Soderberg KA, Payne GW, Sato A, Medzhitov R, Segal SS, Iwasaki A. Innate control of adaptive immunity via remodeling of lymph node feed arteriole. Proceedings of the National Academy of Sciences of the United States of America. 102: 16315-20. PMID 16260739 DOI: 10.1073/Pnas.0506190102  0.773
2005 Sato A, Iwasaki A. Peyer's patch dendritic cells as regulators of mucosal adaptive immunity. Cellular and Molecular Life Sciences : Cmls. 62: 1333-8. PMID 15971108 DOI: 10.1007/s00018-005-5037-z  0.35
2004 Fleeton M, Contractor N, Leon F, He J, Wetzel D, Dermody T, Iwasaki A, Kelsall B. Involvement of dendritic cell subsets in the induction of oral tolerance and immunity. Annals of the New York Academy of Sciences. 1029: 60-5. PMID 15681744 DOI: 10.1196/Annals.1309.008  0.7
2004 Sato A, Iwasaki A. Induction of antiviral immunity requires Toll-like receptor signaling in both stromal and dendritic cell compartments. Proceedings of the National Academy of Sciences of the United States of America. 101: 16274-9. PMID 15534227 DOI: 10.1073/Pnas.0406268101  0.533
2004 Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nature Immunology. 5: 987-95. PMID 15454922 DOI: 10.1038/Ni1112  0.477
2004 Soderberg KA, Linehan MM, Ruddle NH, Iwasaki A. MAdCAM-1 expressing sacral lymph node in the lymphotoxin beta-deficient mouse provides a site for immune generation following vaginal herpes simplex virus-2 infection. Journal of Immunology (Baltimore, Md. : 1950). 173: 1908-13. PMID 15265924 DOI: 10.4049/Jimmunol.173.3.1908  0.744
2004 Lund JM, Alexopoulou L, Sato A, Karow M, Adams NC, Gale NW, Iwasaki A, Flavell RA. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proceedings of the National Academy of Sciences of the United States of America. 101: 5598-603. PMID 15034168 DOI: 10.1073/Pnas.0400937101  0.503
2004 Linehan MM, Richman S, Krummenacher C, Eisenberg RJ, Cohen GH, Iwasaki A. In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosa. Journal of Virology. 78: 2530-6. PMID 14963155 DOI: 10.1128/Jvi.78.5.2530-2536.2004  0.413
2003 Iwasaki A. The role of dendritic cells in immune responses against vaginal infection by herpes simplex virus type 2. Microbes and Infection / Institut Pasteur. 5: 1221-30. PMID 14623018 DOI: 10.1016/J.Micinf.2003.09.006  0.531
2003 Sato A, Hashiguchi M, Toda E, Iwasaki A, Hachimura S, Kaminogawa S. CD11b+ Peyer's patch dendritic cells secrete IL-6 and induce IgA secretion from naive B cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 3684-90. PMID 14500666 DOI: 10.4049/Jimmunol.171.7.3684  0.353
2003 Zhao X, Sato A, Dela Cruz CS, Linehan M, Luegering A, Kucharzik T, Shirakawa AK, Marquez G, Farber JM, Williams I, Iwasaki A. CCL9 is secreted by the follicle-associated epithelium and recruits dome region Peyer's patch CD11b+ dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 2797-803. PMID 12960300 DOI: 10.4049/Jimmunol.171.6.2797  0.345
2003 Lund J, Sato A, Akira S, Medzhitov R, Iwasaki A. Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. The Journal of Experimental Medicine. 198: 513-20. PMID 12900525 DOI: 10.1084/Jem.20030162  0.435
2003 Iwasaki A. The importance of CD11b+ dendritic cells in CD4+ T cell activation in vivo: with help from interleukin 1. The Journal of Experimental Medicine. 198: 185-90. PMID 12860934 DOI: 10.1084/Jem.20030737  0.399
2003 Zhao X, Deak E, Soderberg K, Linehan M, Spezzano D, Zhu J, Knipe DM, Iwasaki A. Vaginal submucosal dendritic cells, but not Langerhans cells, induce protective Th1 responses to herpes simplex virus-2. The Journal of Experimental Medicine. 197: 153-62. PMID 12538655 DOI: 10.1084/Jem.20021109  0.81
2003 FLEETON M, IWASAKI A, CONTRACTOR N, LEON F, HE J, WETZEL D, DERMODY T, KELSALL B. The role of dendritic cells in the induction of oral tolerance and immunity Japanese Journal of Clinical Immunology. 26: 200-200. DOI: 10.2177/Jsci.26.200  0.667
2002 Iwasaki A, Welker R, Mueller S, Linehan M, Nomoto A, Wimmer E. Immunofluorescence analysis of poliovirus receptor expression in Peyer's patches of humans, primates, and CD155 transgenic mice: implications for poliovirus infection. The Journal of Infectious Diseases. 186: 585-92. PMID 12195344 DOI: 10.1086/342682  0.327
2002 Park MK, Amichay D, Love P, Wick E, Liao F, Grinberg A, Rabin RL, Zhang HH, Gebeyehu S, Wright TM, Iwasaki A, Weng Y, DeMartino JA, Elkins KL, Farber JM. The CXC chemokine murine monokine induced by IFN-gamma (CXC chemokine ligand 9) is made by APCs, targets lymphocytes including activated B cells, and supports antibody responses to a bacterial pathogen in vivo. Journal of Immunology (Baltimore, Md. : 1950). 169: 1433-43. PMID 12133969 DOI: 10.4049/Jimmunol.169.3.1433  0.46
2002 Jameson B, Baribaud F, Pöhlmann S, Ghavimi D, Mortari F, Doms RW, Iwasaki A. Expression of DC-SIGN by dendritic cells of intestinal and genital mucosae in humans and rhesus macaques. Journal of Virology. 76: 1866-75. PMID 11799181 DOI: 10.1128/Jvi.76.4.1866-1875.2002  0.352
2001 Iwasaki A, Kelsall BL. Unique functions of CD11b+, CD8 alpha+, and double-negative Peyer's patch dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 166: 4884-90. PMID 11290765 DOI: 10.4049/Jimmunol.166.8.4884  0.637
2000 Iwasaki A, Barber BH. The use of bone marrow-chimeric mice in determining the MHC restriction of epitope-specific cytotoxic T lymphocytes. Methods in Molecular Medicine. 29: 133-44. PMID 21374316 DOI: 10.1385/1-59259-688-6:133  0.635
2000 He J, Gurunathan S, Iwasaki A, Ash-Shaheed B, Kelsall BL. Primary role for Gi protein signaling in the regulation of interleukin 12 production and the induction of T helper cell type 1 responses Journal of Experimental Medicine. 191: 1605-1610. PMID 10790434 DOI: 10.1084/Jem.191.9.1605  0.64
2000 Iwasaki A, Kelsall BL. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3alpha, MIP-3beta, and secondary lymphoid organ chemokine. The Journal of Experimental Medicine. 191: 1381-94. PMID 10770804 DOI: 10.1084/Jem.191.8.1381  0.633
1999 Iwasaki A, Kelsall BL. Freshly isolated Peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. The Journal of Experimental Medicine. 190: 229-39. PMID 10432286 DOI: 10.1084/Jem.190.2.229  0.656
1999 Iwasaki A, Kelsall BL. Mucosal immunity and inflammation. I. Mucosal dendritic cells: their specialized role in initiating T cell responses. The American Journal of Physiology. 276: G1074-8. PMID 10329996 DOI: 10.1152/Ajpgi.1999.276.5.G1074  0.66
1999 Iwasaki A, Dela Cruz CS, Young AR, Barber BH. Epitope-specific cytotoxic T lymphocyte induction by minigene DNA immunization. Vaccine. 17: 2081-8. PMID 10217610 DOI: 10.1016/s0264-410x(98)00411-3  0.648
1998 Porgador A, Irvine KR, Iwasaki A, Barber BH, Restifo NP, Germain RN. Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization Journal of Experimental Medicine. 188: 1075-1082. PMID 9743526 DOI: 10.1084/Jem.188.6.1075  0.685
1998 Iwasaki A, Barber BH. Induction by DNA immunization of a protective antitumor cytotoxic T lymphocyte response against a minimal-epitope-expressing tumor. Cancer Immunology, Immunotherapy : Cii. 45: 273-9. PMID 9439651 DOI: 10.1007/s002620050443  0.652
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