Michael Emerman - Publications

Affiliations: 
Fred Hutchinson Cancer Research Center, Seattle, WA, United States 

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Geiger RA, Khera D, Tenthorey JL, Kochs G, Graf L, Emerman M, Malik HS. Heterozygous and generalist MxA super-restrictors overcome breadth-specificity tradeoffs in antiviral restriction. Biorxiv : the Preprint Server For Biology. PMID 39416221 DOI: 10.1101/2024.10.10.617484  0.615
2024 Gray CN, Ashokkumar M, Janssens DH, Kirchherr J, Allard B, Hsieh E, Hafer TL, Archin NM, Browne EP, Emerman M. Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal. Biorxiv : the Preprint Server For Biology. PMID 39257755 DOI: 10.1101/2024.08.30.610517  0.362
2024 Kulsuptrakul J, Emerman M, Mitchell PS. CARD8 inflammasome activation during HIV-1 cell-to-cell transmission. Biorxiv : the Preprint Server For Biology. PMID 39229127 DOI: 10.1101/2024.08.21.608981  0.568
2024 Bhattacharya T, Alleman EM, Noyola AC, Emerman M, Malik HS. A conserved opal termination codon optimizes a temperature-dependent tradeoff between protein production and processing in alphaviruses. Biorxiv : the Preprint Server For Biology. PMID 39229031 DOI: 10.1101/2024.08.21.609082  0.556
2024 Ashokkumar M, Hafer TL, Felton A, Archin NM, Margolis DM, Emerman M, Browne EP. A targeted CRISPR screen identifies ETS1 as a regulator of HIV latency. Biorxiv : the Preprint Server For Biology. PMID 39211204 DOI: 10.1101/2024.08.03.606477  0.394
2024 Langley CA, Dietzen PA, Emerman M, Tenthorey JL, Malik HS. Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes. Biorxiv : the Preprint Server For Biology. PMID 39149278 DOI: 10.1101/2024.08.06.606855  0.593
2024 Tenthorey JL, Del Banco S, Ramzan I, Klingenberg H, Liu C, Emerman M, Malik HS. Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations. Biorxiv : the Preprint Server For Biology. PMID 38765965 DOI: 10.1101/2024.05.07.592993  0.581
2024 Twentyman J, Emerman M, Ohainle M. Capsid-dependent lentiviral restrictions. Journal of Virology. 98: e0030824. PMID 38497663 DOI: 10.1128/jvi.00308-24  0.802
2023 Hafer TL, Felton A, Delgado Y, Srinivasan H, Emerman M. A CRISPR Screen of HIV Dependency Factors Reveals That Is Non-Essential in T Cells but Required for HIV-1 Reactivation from Latency. Viruses. 15. PMID 37766271 DOI: 10.3390/v15091863  0.368
2023 Twentyman J, Khalifeh A, Felton AL, Emerman M, Ohainle M. Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor. Retrovirology. 20: 15. PMID 37608289 DOI: 10.1186/s12977-023-00629-4  0.828
2023 Hafer TL, Felton A, Delgado Y, Srinivasan H, Emerman M. A CRISPR screen of HIV dependency factors reveals is non-essential in T cells but required for HIV-1 reactivation from latency. Biorxiv : the Preprint Server For Biology. PMID 37546973 DOI: 10.1101/2023.07.28.551016  0.368
2023 Kulsuptrakul J, Turcotte EA, Emerman M, Mitchell PS. A human-specific motif facilitates CARD8 inflammasome activation after HIV-1 infection. Elife. 12. PMID 37417868 DOI: 10.7554/eLife.84108  0.59
2023 Twentyman J, Khalifeh A, Felton AL, Emerman M, OhAinle M. Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor. Biorxiv : the Preprint Server For Biology. PMID 36993223 DOI: 10.1101/2023.03.24.534139  0.828
2023 Li YL, Langley CA, Azumaya CM, Echeverria I, Chesarino NM, Emerman M, Cheng Y, Gross JD. The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature. PMID 36754086 DOI: 10.1038/s41586-023-05779-1  0.389
2023 Montoya VR, Ready TM, Felton A, Fine SR, OhAinle M, Emerman M. A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 Strains. Mbio. e0000923. PMID 36744886 DOI: 10.1128/mbio.00009-23  0.807
2023 Hsieh E, Janssens DH, Paddison PJ, Browne EP, Henikoff S, OhAinle M, Emerman M. A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency. Plos Pathogens. 19: e1011101. PMID 36706161 DOI: 10.1371/journal.ppat.1011101  0.78
2022 Tenthorey JL, Emerman M, Malik HS. Evolutionary Landscapes of Host-Virus Arms Races. Annual Review of Immunology. PMID 35080919 DOI: 10.1146/annurev-immunol-072621-084422  0.612
2021 Chesarino NM, Emerman M. HIV-1 Vif gained breadth in APOBEC3G specificity after cross-species transmission of its precursors. Journal of Virology. JVI0207121. PMID 34908448 DOI: 10.1128/JVI.02071-21  0.33
2020 Tenthorey JL, Young C, Sodeinde A, Emerman M, Malik HS. Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races. Elife. 9. PMID 32930662 DOI: 10.7554/eLife.59988  0.568
2020 Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, O'Meara MJ, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, ... ... Emerman M, et al. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. Biorxiv : the Preprint Server For Biology. PMID 32511329 DOI: 10.1101/2020.03.22.002386  0.687
2020 Yang L, Emerman M, Malik HS, McLaughlin RN. Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates. Elife. 9. PMID 32479260 DOI: 10.7554/eLife.58436  0.626
2020 Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Huettenhain R, Kaake RM, Richards AL, Tutuncuoglu B, ... ... Emerman M, et al. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. PMID 32353859 DOI: 10.1038/S41586-020-2286-9  0.672
2020 McDonnell MM, Crawford KHD, Dingens AS, Bloom JD, Emerman M. APOBEC3C Tandem Domain Proteins Create Super Restriction Factors against HIV-1. Mbio. 11. PMID 32345636 DOI: 10.1128/mBio.00737-20  0.452
2020 Ohainle M, Kim K, Komurlu Keceli S, Felton A, Campbell E, Luban J, Emerman M. TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner. Plos Pathogens. 16: e1008507. PMID 32282853 DOI: 10.1371/Journal.Ppat.1008507  0.8
2020 Chesarino NM, Emerman M. Polymorphisms in Human APOBEC3H Differentially Regulate Ubiquitination and Antiviral Activity. Viruses. 12. PMID 32235597 DOI: 10.3390/v12040378  0.328
2020 Yang L, Emerman M, Malik HS, Jnr RNM. Author response: Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates Elife. DOI: 10.7554/Elife.58436.Sa2  0.572
2020 Planelles V, Emerman M. Decision letter: HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137 Elife. DOI: 10.7554/Elife.55806.Sa1  0.449
2019 Binning JM, Chesarino NM, Emerman M, Gross JD. Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism. Cell Host & Microbe. 26: 739-747.e4. PMID 31830442 DOI: 10.1016/J.Chom.2019.10.014  0.421
2019 Colón-Thillet R, Hsieh E, Graf L, McLaughlin RN, Young JM, Kochs G, Emerman M, Malik HS. Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins. Plos Biology. 17: e3000181. PMID 31574080 DOI: 10.1371/Journal.Pbio.3000181  0.618
2019 Sharma A, McLaughlin RN, Basom RS, Kikawa C, OhAinle M, Yount JS, Emerman M, Overbaugh J. Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner. Plos Pathogens. 15: e1007925. PMID 31260493 DOI: 10.1371/Journal.Ppat.1007925  0.836
2019 Emerman M, Freed E. Decision letter: KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides Elife. DOI: 10.7554/Elife.46767.021  0.397
2018 OhAinle M, Helms L, Vermeire J, Roesch F, Humes D, Basom R, Delrow JJ, Overbaugh J, Emerman M. A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV. Elife. 7. PMID 30520725 DOI: 10.7554/Elife.39823  0.805
2018 Garcia EI, Emerman M. Recurrent Loss of APOBEC3H Activity during Primate Evolution. Journal of Virology. PMID 29925657 DOI: 10.1128/Jvi.00971-18  0.5
2018 Roesch F, OhAinle M, Emerman M. A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery. Retrovirology. 15: 26. PMID 29554922 DOI: 10.1186/S12977-018-0409-2  0.822
2018 OhAinle M, Helms L, Vermeire J, Roesch F, Humes D, Basom R, Delrow JJ, Overbaugh J, Emerman M. Author response: A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV Elife. DOI: 10.7554/Elife.39823.034  0.803
2017 Baldauf HM, Stegmann L, Schwarz SM, Ambiel I, Trotard M, Martin M, Burggraf M, Lenzi GM, Lejk H, Pan X, Fregoso OI, Lim ES, Abraham L, Nguyen LA, Rutsch F, ... ... Emerman M, et al. Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28228523 DOI: 10.1073/Pnas.1613635114  0.817
2017 Adolph MB, Ara A, Feng Y, Wittkopp CJ, Emerman M, Fraser JS, Chelico L. Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization. Nucleic Acids Research. PMID 28158858 DOI: 10.1093/Nar/Gkx066  0.41
2016 Wittkopp CJ, Adolph MB, Wu LI, Chelico L, Emerman M. A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses. Plos Pathogens. 12: e1005865. PMID 27732658 DOI: 10.1371/Journal.Ppat.1005865  0.504
2016 Fregoso OI, Emerman M. Activation of the DNA Damage Response Is a Conserved Function of HIV-1 and HIV-2 Vpr That Is Independent of SLX4 Recruitment. Mbio. 7. PMID 27624129 DOI: 10.1128/Mbio.01433-16  0.786
2016 McLaughlin RN, Gable JT, Wittkopp CJ, Emerman M, Malik HS. Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution. Molecular Biology and Evolution. PMID 27189538 DOI: 10.1093/Molbev/Msw070  0.627
2016 Zurnic I, Hütter S, Lehmann U, Stanke N, Reh J, Kern T, Lindel F, Gerresheim G, Hamann M, Müllers E, Lesbats P, Cherepanov P, Serrao E, Engelman A, Lindemann D, ... ... Emerman M, et al. Proceedings of the Frontiers of Retrovirology Conference 2016 Retrovirology. 13. DOI: 10.1186/S12977-016-0294-5  0.745
2015 Mitchell PS, Young JM, Emerman M, Malik HS. Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction. Plos Pathogens. 11: e1005304. PMID 26658285 DOI: 10.1371/Journal.Ppat.1005304  0.768
2015 Etienne L, Bibollet-Ruche F, Sudmant PH, Wu LI, Hahn BH, Emerman M. The Role of the Antiviral APOBEC3 Gene Family in Protecting Chimpanzees against Lentiviruses from Monkeys. Plos Pathogens. 11: e1005149. PMID 26394054 DOI: 10.1371/Journal.Ppat.1005149  0.557
2014 Refsland EW, Hultquist JF, Luengas EM, Ikeda T, Shaban NM, Law EK, Brown WL, Reilly C, Emerman M, Harris RS. Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity. Plos Genetics. 10: e1004761. PMID 25411794 DOI: 10.1371/Journal.Pgen.1004761  0.583
2014 Matsen FA, Small CT, Soliven K, Engel GA, Feeroz MM, Wang X, Craig KL, Hasan MK, Emerman M, Linial ML, Jones-Engel L. A novel Bayesian method for detection of APOBEC3-mediated hypermutation and its application to zoonotic transmission of simian foamy viruses. Plos Computational Biology. 10: e1003493. PMID 24586139 DOI: 10.1371/Journal.Pcbi.1003493  0.432
2013 Spragg CJ, Emerman M. Antagonism of SAMHD1 is actively maintained in natural infections of simian immunodeficiency virus. Proceedings of the National Academy of Sciences of the United States of America. 110: 21136-41. PMID 24324150 DOI: 10.1073/Pnas.1316839110  0.595
2013 Malfavon-Borja R, Sawyer SL, Wu LI, Emerman M, Malik HS. An evolutionary screen highlights canonical and noncanonical candidate antiviral genes within the primate TRIM gene family. Genome Biology and Evolution. 5: 2141-54. PMID 24158625 DOI: 10.1093/Gbe/Evt163  0.751
2013 Etienne L, Emerman M. The mongoose, the pheasant, the pox, and the retrovirus. Plos Biology. 11: e1001641. PMID 24013523 DOI: 10.1371/Journal.Pbio.1001641  0.457
2013 Compton AA, Malik HS, Emerman M. Host gene evolution traces the evolutionary history of ancient primate lentiviruses. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120496. PMID 23938749 DOI: 10.1098/Rstb.2012.0496  0.791
2013 Fregoso OI, Ahn J, Wang C, Mehrens J, Skowronski J, Emerman M. Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1. Plos Pathogens. 9: e1003496. PMID 23874202 DOI: 10.1371/Journal.Ppat.1003496  0.817
2013 Etienne L, Hahn BH, Sharp PM, Matsen FA, Emerman M. Gene loss and adaptation to hominids underlie the ancient origin of HIV-1. Cell Host & Microbe. 14: 85-92. PMID 23870316 DOI: 10.1016/J.Chom.2013.06.002  0.572
2013 Duggal NK, Fu W, Akey JM, Emerman M. Identification and antiviral activity of common polymorphisms in the APOBEC3 locus in human populations. Virology. 443: 329-37. PMID 23755966 DOI: 10.1016/J.Virol.2013.05.016  0.661
2013 Mitchell PS, Emerman M, Malik HS. An evolutionary perspective on the broad antiviral specificity of MxA. Current Opinion in Microbiology. 16: 493-9. PMID 23725670 DOI: 10.1016/J.Mib.2013.04.005  0.722
2013 Compton AA, Emerman M. Convergence and divergence in the evolution of the APOBEC3G-Vif interaction reveal ancient origins of simian immunodeficiency viruses. Plos Pathogens. 9: e1003135. PMID 23359341 DOI: 10.1371/Journal.Ppat.1003135  0.702
2013 Malfavon-Borja R, Wu LI, Emerman M, Malik HS. Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes. Proceedings of the National Academy of Sciences of the United States of America. 110: E583-92. PMID 23319649 DOI: 10.1073/Pnas.1216542110  0.659
2012 Mitchell PS, Patzina C, Emerman M, Haller O, Malik HS, Kochs G. Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA. Cell Host & Microbe. 12: 598-604. PMID 23084925 DOI: 10.1016/J.Chom.2012.09.005  0.713
2012 Duggal NK, Emerman M. Evolutionary conflicts between viruses and restriction factors shape immunity. Nature Reviews. Immunology. 12: 687-95. PMID 22976433 DOI: 10.1038/Nri3295  0.679
2012 Lim ES, Wu LI, Malik HS, Emerman M. The function and evolution of the restriction factor Viperin in primates was not driven by lentiviruses. Retrovirology. 9: 55. PMID 22734835 DOI: 10.1186/1742-4690-9-55  0.797
2012 Lim ES, Fregoso OI, McCoy CO, Matsen FA, Malik HS, Emerman M. The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. Cell Host & Microbe. 11: 194-204. PMID 22284954 DOI: 10.1016/J.Chom.2012.01.004  0.814
2012 Compton AA, Hirsch VM, Emerman M. The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict. Cell Host & Microbe. 11: 91-8. PMID 22264516 DOI: 10.1016/J.Chom.2011.11.010  0.714
2011 Yu SF, Lujan P, Jackson DL, Emerman M, Linial ML. The DEAD-box RNA helicase DDX6 is required for efficient encapsidation of a retroviral genome. Plos Pathogens. 7: e1002303. PMID 22022269 DOI: 10.1371/Journal.Ppat.1002303  0.361
2011 Patel MR, Emerman M, Malik HS. Paleovirology - ghosts and gifts of viruses past. Current Opinion in Virology. 1: 304-9. PMID 22003379 DOI: 10.1016/J.Coviro.2011.06.007  0.661
2011 Duggal NK, Malik HS, Emerman M. The breadth of antiviral activity of Apobec3DE in chimpanzees has been driven by positive selection. Journal of Virology. 85: 11361-71. PMID 21835794 DOI: 10.1128/Jvi.05046-11  0.783
2011 Lim ES, Emerman M. HIV: Going for the watchman. Nature. 474: 587-8. PMID 21720361 DOI: 10.1038/474587A  0.708
2011 Li MM, Emerman M. Polymorphism in human APOBEC3H affects a phenotype dominant for subcellular localization and antiviral activity. Journal of Virology. 85: 8197-207. PMID 21653666 DOI: 10.1128/Jvi.00624-11  0.558
2011 Tareen SU, Emerman M. Trim5 TAKes on pattern recognition. Cell Host & Microbe. 9: 349-50. PMID 21575904 DOI: 10.1016/J.Chom.2011.05.003  0.785
2011 Tareen SU, Emerman M. Human Trim5α has additional activities that are uncoupled from retroviral capsid recognition. Virology. 409: 113-20. PMID 21035162 DOI: 10.1016/J.Virol.2010.09.018  0.805
2011 Emerman M. The little book of viruses Plos Biology. 9. DOI: 10.1371/Journal.Pbio.1001139  0.515
2010 Lim ES, Malik HS, Emerman M. Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses. Journal of Virology. 84: 7124-34. PMID 20444900 DOI: 10.1128/Jvi.00468-10  0.783
2010 Emerman M, Malik HS. Paleovirology--modern consequences of ancient viruses. Plos Biology. 8: e1000301. PMID 20161719 DOI: 10.1371/Journal.Pbio.1000301  0.685
2010 Li MM, Wu LI, Emerman M. The range of human APOBEC3H sensitivity to lentiviral Vif proteins. Journal of Virology. 84: 88-95. PMID 19828612 DOI: 10.1128/Jvi.01344-09  0.657
2009 Lim ES, Emerman M. Simian immunodeficiency virus SIVagm from African green monkeys does not antagonize endogenous levels of African green monkey tetherin/BST-2. Journal of Virology. 83: 11673-81. PMID 19726508 DOI: 10.1128/Jvi.00569-09  0.688
2009 Yamashita M, Emerman M. Cellular restriction targeting viral capsids perturbs human immunodeficiency virus type 1 infection of nondividing cells. Journal of Virology. 83: 9835-43. PMID 19625401 DOI: 10.1128/Jvi.01084-09  0.51
2009 Voronin Y, Holte S, Overbaugh J, Emerman M. Genetic drift of HIV populations in culture. Plos Genetics. 5: e1000431. PMID 19300501 DOI: 10.1371/Journal.Pgen.1000431  0.447
2009 Tareen SU, Sawyer SL, Malik HS, Emerman M. An expanded clade of rodent Trim5 genes. Virology. 385: 473-83. PMID 19147168 DOI: 10.1016/J.Virol.2008.12.018  0.794
2009 LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, et al. Guidelines for naming nonprimate APOBEC3 genes and proteins. Journal of Virology. 83: 494-7. PMID 18987154 DOI: 10.1128/Jvi.01976-08  0.544
2008 Diehl WE, Stansell E, Kaiser SM, Emerman M, Hunter E. Identification of postentry restrictions to Mason-Pfizer monkey virus infection in New World monkey cells. Journal of Virology. 82: 11140-51. PMID 18799582 DOI: 10.1128/Jvi.00269-08  0.701
2008 OhAinle M, Kerns JA, Li MM, Malik HS, Emerman M. Antiretroelement activity of APOBEC3H was lost twice in recent human evolution. Cell Host & Microbe. 4: 249-59. PMID 18779051 DOI: 10.1016/J.Chom.2008.07.005  0.82
2008 Lin TY, Emerman M. Determinants of cyclophilin A-dependent TRIM5 alpha restriction against HIV-1. Virology. 379: 335-41. PMID 18678385 DOI: 10.1016/J.Virol.2008.06.037  0.622
2008 Malim MH, Emerman M. HIV-1 accessory proteins--ensuring viral survival in a hostile environment. Cell Host & Microbe. 3: 388-98. PMID 18541215 DOI: 10.1016/J.Chom.2008.04.008  0.537
2008 Kerns JA, Emerman M, Malik HS. Positive selection and increased antiviral activity associated with the PARP-containing isoform of human zinc-finger antiviral protein. Plos Genetics. 4: e21. PMID 18225958 DOI: 10.1371/Journal.Pgen.0040021  0.7
2007 Sawyer SL, Emerman M, Malik HS. Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals. Plos Pathogens. 3: e197. PMID 18159944 DOI: 10.1371/Journal.Ppat.0030197  0.756
2007 Yamashita M, Perez O, Hope TJ, Emerman M. Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells. Plos Pathogens. 3: 1502-10. PMID 17967060 DOI: 10.1371/Journal.Ppat.0030156  0.455
2007 Voronin Y, Chohan B, Emerman M, Overbaugh J. Primary isolates of human immunodeficiency virus type 1 are usually dominated by the major variants found in blood. Journal of Virology. 81: 10232-41. PMID 17652386 DOI: 10.1128/Jvi.01035-07  0.459
2007 Kaiser SM, Malik HS, Emerman M. Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein. Science (New York, N.Y.). 316: 1756-8. PMID 17588933 DOI: 10.1126/Science.1140579  0.819
2006 Lin TY, Emerman M. Cyclophilin A interacts with diverse lentiviral capsids. Retrovirology. 3: 70. PMID 17038183 DOI: 10.1186/1742-4690-3-70  0.615
2006 Lewinski MK, Yamashita M, Emerman M, Ciuffi A, Marshall H, Crawford G, Collins F, Shinn P, Leipzig J, Hannenhalli S, Berry CC, Ecker JR, Bushman FD. Retroviral DNA integration: viral and cellular determinants of target-site selection. Plos Pathogens. 2: e60. PMID 16789841 DOI: 10.1371/Journal.Ppat.0020060  0.516
2006 OhAinle M, Kerns JA, Malik HS, Emerman M. Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H. Journal of Virology. 80: 3853-62. PMID 16571802 DOI: 10.1128/Jvi.80.8.3853-3862.2006  0.83
2006 Emerman M. How TRIM5alpha defends against retroviral invasions. Proceedings of the National Academy of Sciences of the United States of America. 103: 5249-50. PMID 16567650 DOI: 10.1073/Pnas.0601373103  0.508
2006 Sawyer SL, Wu LI, Akey JM, Emerman M, Malik HS. High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans. Current Biology : Cb. 16: 95-100. PMID 16401428 DOI: 10.1016/J.Cub.2005.11.045  0.767
2006 Kaiser SM, Emerman M. Uracil DNA glycosylase is dispensable for human immunodeficiency virus type 1 replication and does not contribute to the antiviral effects of the cytidine deaminase Apobec3G. Journal of Virology. 80: 875-82. PMID 16378989 DOI: 10.1128/Jvi.80.2.875-882.2006  0.777
2006 Yamashita M, Emerman M. Retroviral infection of non-dividing cells: old and new perspectives. Virology. 344: 88-93. PMID 16364740 DOI: 10.1016/J.Virol.2005.09.012  0.454
2005 Voronin Y, Overbaugh J, Emerman M. Simian immunodeficiency virus variants that differ in pathogenicity differ in fitness under rapid cell turnover conditions. Journal of Virology. 79: 15091-8. PMID 16306580 DOI: 10.1128/Jvi.79.24.15091-15098.2005  0.412
2005 Yamashita M, Emerman M. The cell cycle independence of HIV infections is not determined by known karyophilic viral elements. Plos Pathogens. 1: e18. PMID 16292356 DOI: 10.1371/Journal.Ppat.0010018  0.533
2005 Sawyer SL, Wu LI, Emerman M, Malik HS. Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proceedings of the National Academy of Sciences of the United States of America. 102: 2832-7. PMID 15689398 DOI: 10.1073/Pnas.0409853102  0.785
2004 Sawyer SL, Emerman M, Malik HS. Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G. Plos Biology. 2: E275. PMID 15269786 DOI: 10.1371/Journal.Pbio.0020275  0.789
2004 Yamashita M, Emerman M. Capsid is a dominant determinant of retrovirus infectivity in nondividing cells. Journal of Virology. 78: 5670-8. PMID 15140964 DOI: 10.1128/Jvi.78.11.5670-5678.2004  0.494
2004 Kaiser SM, Emerman M. Controlling lentiviruses: single amino acid changes can determine specificity. Proceedings of the National Academy of Sciences of the United States of America. 101: 3725-6. PMID 15010528 DOI: 10.1073/Pnas.0400929101  0.752
2004 Goh WC, Manel N, Emerman M. The human immunodeficiency virus Vpr protein binds Cdc25C: implications for G2 arrest. Virology. 318: 337-49. PMID 14972559 DOI: 10.1016/J.Virol.2003.10.007  0.413
2003 Gummuluru S, Rogel M, Stamatatos L, Emerman M. Binding of human immunodeficiency virus type 1 to immature dendritic cells can occur independently of DC-SIGN and mannose binding C-type lectin receptors via a cholesterol-dependent pathway. Journal of Virology. 77: 12865-74. PMID 14610207 DOI: 10.1128/Jvi.77.23.12865-12874.2003  0.433
2002 Gummuluru S, Emerman M. Advances in HIV molecular biology. Aids (London, England). 16: S17-23. PMID 12698995 DOI: 10.1097/00002030-200216004-00003  0.392
2002 McDonald D, Vodicka MA, Lucero G, Svitkina TM, Borisy GG, Emerman M, Hope TJ. Visualization of the intracellular behavior of HIV in living cells. The Journal of Cell Biology. 159: 441-52. PMID 12417576 DOI: 10.1083/Jcb.200203150  0.455
2002 Dvorin JD, Bell P, Maul GG, Yamashita M, Emerman M, Malim MH. Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import. Journal of Virology. 76: 12087-96. PMID 12414950 DOI: 10.1128/Jvi.76.23.12087-12096.2002  0.528
2002 Gummuluru S, KewalRamani VN, Emerman M. Dendritic cell-mediated viral transfer to T cells is required for human immunodeficiency virus type 1 persistence in the face of rapid cell turnover. Journal of Virology. 76: 10692-701. PMID 12368311 DOI: 10.1128/Jvi.76.21.10692-10701.2002  0.461
2002 Somasundaran M, Sharkey M, Brichacek B, Luzuriaga K, Emerman M, Sullivan JL, Stevenson M. Evidence for a cytopathogenicity determinant in HIV-1 Vpr. Proceedings of the National Academy of Sciences of the United States of America. 99: 9503-8. PMID 12093916 DOI: 10.1073/Pnas.142313699  0.52
2002 Lewinsohn DA, Lines R, Lewinsohn DM, Riddell SR, Greenberg PD, Emerman M, Bartz SR. HIV-1 Vpr does not inhibit CTL-mediated apoptosis of HIV-1 infected cells. Virology. 294: 13-21. PMID 11886261 DOI: 10.1006/Viro.2001.1294  0.466
2001 Bouyac-Bertoia M, Dvorin JD, Fouchier RA, Jenkins Y, Meyer BE, Wu LI, Emerman M, Malim MH. HIV-1 infection requires a functional integrase NLS. Molecular Cell. 7: 1025-35. PMID 11389849 DOI: 10.1016/S1097-2765(01)00240-4  0.514
2001 Malim MH, Emerman M. HIV-1 sequence variation: drift, shift, and attenuation. Cell. 104: 469-72. PMID 11239404 DOI: 10.1016/S0092-8674(01)00234-3  0.48
2000 Gummuluru S, Kinsey CM, Emerman M. An in vitro rapid-turnover assay for human immunodeficiency virus type 1 replication selects for cell-to-cell spread of virus. Journal of Virology. 74: 10882-91. PMID 11069982 DOI: 10.1128/Jvi.74.23.10882-10891.2000  0.438
2000 Harrington R, Wu L, Pullen H, Emerman M. Direct detection of infectious HIV-1 in blood using a centrifugation-indicator cell assay. Journal of Virological Methods. 88: 111-5. PMID 10921848 DOI: 10.1016/S0166-0934(00)00181-6  0.453
2000 Holtea S, Emerman M. A competition model for viral inhibition of host cell proliferation. Mathematical Biosciences. 166: 69-84. PMID 10882800 DOI: 10.1016/S0025-5564(00)00020-1  0.479
2000 Emerman M. Learning from lentiviruses. Nature Genetics. 24: 8-9. PMID 10615115 DOI: 10.1038/71740  0.484
1999 Gummuluru S, Emerman M. Cell cycle- and Vpr-mediated regulation of human immunodeficiency virus type 1 expression in primary and transformed T-cell lines. Journal of Virology. 73: 5422-30. PMID 10364289 DOI: 10.1128/Jvi.73.7.5422-5430.1999  0.483
1999 Bartz SR, Emerman M. Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8. Journal of Virology. 73: 1956-63. PMID 9971775 DOI: 10.1128/Jvi.73.3.1956-1963.1999  0.461
1999 Goh WC, Markee J, Akridge RE, Meldorf M, Musey L, Karchmer T, Krone M, Collier A, Corey L, Emerman M, McElrath MJ. Protection against human immunodeficiency virus type 1 infection in persons with repeated exposure: evidence for T cell immunity in the absence of inherited CCR5 coreceptor defects. The Journal of Infectious Diseases. 179: 548-57. PMID 9952360 DOI: 10.1086/314632  0.5
1999 Gummuluru S, Emerman M. Cell Cycle- and Vpr-Mediated Regulation of Human Immunodeficiency Virus Type 1 Expression in Primary and Transformed T-Cell Lines Journal of Virology. 73: 5422-5430. DOI: 10.1128/jvi.73.7.5422-5430.1999  0.382
1998 Emerman M, Malim MH. HIV-1 regulatory/accessory genes: keys to unraveling viral and host cell biology. Science (New York, N.Y.). 280: 1880-4. PMID 9632380 DOI: 10.1126/Science.280.5371.1880  0.562
1998 Agosto M, Allan J, Benson C, Berger EA, Blumenthal R, Burton D, Clements J, Coffin J, Connor R, Cullen B, Desrosiers R, Dimitrov D, Doms R, Emerman M, Feinberg M, et al. AIDS vaccine development. Science (New York, N.Y.). 280: 803, 804-5. PMID 9599148 DOI: 10.1126/Science.280.5365.803C  0.364
1998 Vodicka MA, Koepp DM, Silver PA, Emerman M. HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection. Genes & Development. 12: 175-85. PMID 9436978 DOI: 10.1101/Gad.12.2.175  0.414
1998 Goh WC, Rogel ME, Kinsey CM, Michael SF, Fultz PN, Nowak MA, Hahn BH, Emerman M. HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo. Nature Medicine. 4: 65-71. PMID 9427608 DOI: 10.1038/Nm0198-065  0.526
1997 Vodicka MA, Goh WC, Wu LI, Rogel ME, Bartz SR, Schweickart VL, Raport CJ, Emerman M. Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses. Virology. 233: 193-8. PMID 9201229 DOI: 10.1006/Viro.1997.8606  0.458
1997 Gu J, Emerman M, Sandmeyer S. Small heat shock protein suppression of Vpr-induced cytoskeletal defects in budding yeast. Molecular and Cellular Biology. 17: 4033-42. PMID 9199338 DOI: 10.1128/Mcb.17.7.4033  0.363
1997 Selig L, Benichou S, Rogel ME, Wu LI, Vodicka MA, Sire J, Benarous R, Emerman M. Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest. Journal of Virology. 71: 4842-6. PMID 9151883 DOI: 10.1128/Jvi.71.6.4842-4846.1997  0.528
1997 Stivahtis GL, Soares MA, Vodicka MA, Hahn BH, Emerman M. Conservation and host specificity of Vpr-mediated cell cycle arrest suggest a fundamental role in primate lentivirus evolution and biology. Journal of Virology. 71: 4331-8. PMID 9151821 DOI: 10.1128/Jvi.71.6.4331-4338.1997  0.53
1996 Emerman M. From curse to cure: HIV for gene therapy? Nature Biotechnology. 14: 943. PMID 9631028 DOI: 10.1038/Nbt0896-943  0.414
1996 Fletcher TM, Brichacek B, Sharova N, Newman MA, Stivahtis G, Sharp PM, Emerman M, Hahn BH, Stevenson M. Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM). The Embo Journal. 15: 6155-65. PMID 8947037 DOI: 10.1002/J.1460-2075.1996.Tb01003.X  0.545
1996 Sharp PM, Bailes E, Stevenson M, Emerman M, Hahn BH. Gene acquisition in HIV and SIV. Nature. 383: 586-7. PMID 8857532 DOI: 10.1038/383586A0  0.455
1996 Emerman M. HIV-1, Vpr and the cell cycle. Current Biology : Cb. 6: 1096-103. PMID 8805364 DOI: 10.1016/S0960-9822(02)00676-0  0.513
1996 Bartz SR, Rogel ME, Emerman M. Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control. Journal of Virology. 70: 2324-31. PMID 8642659 DOI: 10.1128/Jvi.70.4.2324-2331.1996  0.472
1996 Kewalramani VN, Emerman M. Vpx association with mature core structures of HIV-2. Virology. 218: 159-68. PMID 8615019 DOI: 10.1006/Viro.1996.0176  0.446
1996 Kewalramani VN, Park CS, Gallombardo PA, Emerman M. Protein stability influences human immunodeficiency virus type 2 Vpr virion incorporation and cell cycle effect. Virology. 218: 326-34. PMID 8610459 DOI: 10.1006/Viro.1996.0201  0.476
1995 Rogel ME, Wu LI, Emerman M. The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection. Journal of Virology. 69: 882-8. PMID 7815556 DOI: 10.1128/Jvi.69.2.882-888.1995  0.503
1995 Stevenson M, Brichacek B, Heinzinger N, Swindells S, Pirruccello S, Janoff E, Emerman M. Molecular basis of cell cycle dependent HIV-1 replication. Implications for control of virus burden. Advances in Experimental Medicine and Biology. 374: 33-45. PMID 7572399 DOI: 10.1007/978-1-4615-1995-9_4  0.511
1995 Deminie CA, Emerman M. [12] Quantitation of virus stocks produced from cloned human immunodeficiency virus DNA Methods in Molecular Genetics. 7: 195-208. DOI: 10.1016/S1067-2389(06)80044-0  0.31
1994 Lewis PF, Emerman M. Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus. Journal of Virology. 68: 510-6. PMID 8254763 DOI: 10.1128/Jvi.68.1.510-516.1994  0.44
1994 Deminie CA, Emerman M. Functional exchange of an oncoretrovirus and a lentivirus matrix protein. Journal of Virology. 68: 4442-9. PMID 8207817 DOI: 10.1128/Jvi.68.7.4442-4449.1994  0.534
1994 Adams M, Sharmeen L, Kimpton J, Romeo JM, Garcia JV, Peterlin BM, Groudine M, Emerman M. Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts. Proceedings of the National Academy of Sciences of the United States of America. 91: 3862-6. PMID 8171003 DOI: 10.1073/Pnas.91.9.3862  0.497
1994 Heinzinger NK, Bukrinsky MI, Haggerty SA, Ragland AM, Kewalramani V, Lee MA, Gendelman HE, Ratner L, Stevenson M, Emerman M. The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 7311-5. PMID 8041786 DOI: 10.1073/Pnas.91.15.7311  0.546
1994 Emerman M, Bukrinsky M, Stevenson M. HIV-1 infection of non-dividing cells Nature. 369: 108-108. DOI: 10.1038/369108A0  0.429
1994 Emerman M, Bukrinsky M, Stevenson M. HIV-1 infection of non-dividing cells [6] Nature. 369: 108.  0.316
1993 Deminie CA, Emerman M. Incorporation of human immunodeficiency virus type 1 Gag proteins into murine leukemia virus virions. Journal of Virology. 67: 6499-506. PMID 8411353 DOI: 10.1128/Jvi.67.11.6499-6506.1993  0.515
1993 Bukrinsky MI, Haggerty S, Dempsey MP, Sharova N, Adzhubel A, Spitz L, Lewis P, Goldfarb D, Emerman M, Stevenson M. A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells. Nature. 365: 666-9. PMID 8105392 DOI: 10.1038/365666A0  0.504
1992 Paulous S, Emerman M, Keller R, Montagnier L, Cordonnier A. Functional mapping of the rev-responsive element of human immunodeficiency virus type 2 (HIV-2): influence of HIV-2 envelope-encoding sequences on HIV-1 gp120 expression in the presence or absence of Rev. The Journal of General Virology. 73: 1773-80. PMID 1629702 DOI: 10.1099/0022-1317-73-7-1773  0.503
1992 Kimpton J, Emerman M. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene. Journal of Virology. 66: 2232-9. PMID 1548759 DOI: 10.1128/Jvi.66.4.2232-2239.1992  0.468
1992 Lewis P, Hensel M, Emerman M. Human immunodeficiency virus infection of cells arrested in the cell cycle. The Embo Journal. 11: 3053-8. PMID 1322294 DOI: 10.1002/J.1460-2075.1992.Tb05376.X  0.487
1992 Kewalramani VN, Panganiban AT, Emerman M. Spleen necrosis virus, an avian immunosuppressive retrovirus, shares a receptor with the type D simian retroviruses. Journal of Virology. 66: 3026-31. PMID 1313915 DOI: 10.1128/Jvi.66.5.3026-3031.1992  0.395
1991 Peden K, Emerman M, Montagnier L. Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI. Virology. 185: 661-72. PMID 1683726 DOI: 10.1016/0042-6822(91)90537-L  0.507
1990 Rocancourt D, Bonnerot C, Jouin H, Emerman M, Nicolas JF. Activation of a beta-galactosidase recombinant provirus: application to titration of human immunodeficiency virus (HIV) and HIV-infected cells. Journal of Virology. 64: 2660-8. PMID 2110596 DOI: 10.1128/Jvi.64.6.2660-2668.1990  0.486
1989 Chakrabarti L, Emerman M, Tiollais P, Sonigo P. The cytoplasmic domain of simian immunodeficiency virus transmembrane protein modulates infectivity. Journal of Virology. 63: 4395-403. PMID 2778881 DOI: 10.1128/Jvi.63.10.4395-4403.1989  0.459
1989 Guyader M, Emerman M, Montagnier L, Peden K. VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytes. The Embo Journal. 8: 1169-75. PMID 2743977 DOI: 10.1002/J.1460-2075.1989.Tb03488.X  0.499
1989 Emerman M, Vazeux R, Peden K. The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization. Cell. 57: 1155-65. PMID 2736624 DOI: 10.1016/0092-8674(89)90053-6  0.348
1989 Cordonnier A, Rivière Y, Montagnier L, Emerman M. Effects of mutations in hyperconserved regions of the extracellular glycoprotein of human immunodeficiency virus type 1 on receptor binding. Journal of Virology. 63: 4464-8. PMID 2550679 DOI: 10.1128/Jvi.63.10.4464-4468.1989  0.38
1989 Cordonnier A, Montagnier L, Emerman M. Single amino-acid changes in HIV envelope affect viral tropism and receptor binding. Nature. 340: 571-4. PMID 2475780 DOI: 10.1038/340571A0  0.447
1987 Rhode BW, Emerman M, Temin HM. Instability of large direct repeats in retrovirus vectors. Journal of Virology. 61: 925-7. PMID 3806800 DOI: 10.1128/Jvi.61.3.925-927.1987  0.578
1987 Guyader M, Emerman M, Sonigo P, Clavel F, Montagnier L, Alizon M. Genome organization and transactivation of the human immunodeficiency virus type 2. Nature. 326: 662-9. PMID 3031510 DOI: 10.1038/326662A0  0.496
1987 Emerman M, Guyader M, Montagnier L, Baltimore D, Muesing MA. The specificity of the human immunodeficiency virus type 2 transactivator is different from that of human immunodeficiency virus type 1. The Embo Journal. 6: 3755-60. PMID 2828036 DOI: 10.1002/J.1460-2075.1987.Tb02710.X  0.471
1986 Emerman M, Temin HM. Comparison of promoter suppression in avian and murine retrovirus vectors. Nucleic Acids Research. 14: 9381-96. PMID 3025812 DOI: 10.1093/Nar/14.23.9381  0.608
1986 Emerman M, Temin HM. Quantitative analysis of gene suppression in integrated retrovirus vectors. Molecular and Cellular Biology. 6: 792-800. PMID 3022130 DOI: 10.1128/Mcb.6.3.792  0.593
1986 Emerman M, Temin HM. Comparison of promoter suppression in avian and murine retrovirus vectors Nucleic Acids Research. 14: 9381-9396. DOI: 10.1093/nar/14.23.9381  0.516
1985 Emerman M, Panganiban AT, Temin HM. Insertion of genes into retrovirus genomes and of retrovirus DNA into cell genomes. Progress in Medical Virology. Fortschritte Der Medizinischen Virusforschung. ProgrèS En Virologie MéDicale. 32: 174-88. PMID 3895298  0.498
1984 Emerman M, Temin HM. High-frequency deletion in recovered retrovirus vectors containing exogenous DNA with promoters. Journal of Virology. 50: 42-9. PMID 6321798 DOI: 10.1128/Jvi.50.1.42-49.1984  0.6
1984 Emerman M, Temin HM. Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism. Cell. 39: 449-67. PMID 6096005 DOI: 10.1016/0092-8674(84)90453-7  0.534
1984 Emerman M, Temin HM. Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism Cell. 39: 459-467. DOI: 10.1016/0092-8674(84)90453-7  0.582
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